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RA CAPITAL MANAGEMENT, L.P.

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13F filer, CIK 1346824, BOSTON, MA

RA CAPITAL MANAGEMENT, L.P. reported $11,507,522,068 across 84 holdings for the quarter ended 2026-06-30, in a 13F-HR filed 2026-08-14. Its ten largest share positions make up 60.42% of the portfolio.

Filed (acceptance time not in the bulk data set), ingested 13F-HR 0001104659-26-097251

Period
2026-06-30
Reported value
$11.5B
Holdings
84
Top 10 weight
60.42%
New
17
Sold out
18

Part of the filer group RA CAPITAL MANAGEMENT, L.P.

How groups are built

Stakes and trades reported after 2026-06-30

13D, 13G and Form 4 filings by this filer's group, dated after the 13F period, on securities the quarter does not hold as shares.

  • WVE WAVE LIFE SCIENCES INC: Form 4 granted 10,700 shares on 2026-10-05, 0001231919-26-001433Timeline
    Accepted , ingested
  • CRBP CORBUS PHARMACEUTICALS HLDGS: 13G 1,914,788 shares, 9.9% of the class, 13G filed 2026-09-30, 0001346824-26-000243Timeline
    Accepted , ingested

Largest buys vs the previous quarter

SecurityShares changeApprox. value
ASNDnew+10,281,496$2.74B
PBLSnew+28,933,371$792M
COAGnew+7,808,627$287M
ABVXnew+1,132,557$151M
ORKAnew+1,554,597$148M

Ranked by the share change valued at this quarter's implied price (value over shares in the 13F). A position sold out is valued at the previous quarter's price, its last report.

Largest sells vs the previous quarter

SecurityShares changeApprox. value
ASNDexited-10,281,496-$2.35B
DNTHexited-2,611,733-$219M
NUVLreduced-1,287,689-$159M
PRAXexited-373,787-$120M
SRPTexited-3,902,596-$84.9M

Ranked by the share change valued at this quarter's implied price (value over shares in the 13F). A position sold out is valued at the previous quarter's price, its last report.

Holdings, Q2 2026

Share positions as resolved from 13F-HR 0001104659-26-097251, largest first. % of portfolio is the value over $11,507,522,068, the sum of the share positions whose value is usable for ratios (method).

SecurityHistorySharesValue% of portfolioChangeLatest eventTimeline
ASNDASCENDIS PHARMA A/SQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: not reported; 2026Q1: not reported; 2026Q2: 10,281,496 shares 10,281,496$2.74B23.83%newTimeline
PBLSPARABILIS MEDICINES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: not reported; 2026Q1: not reported; 2026Q2: 28,933,371 shares 28,933,371$792M6.88%newTimeline
RYTMRHYTHM PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: 6,084,412 shares; 2024Q4: 6,084,412 shares; 2025Q1: 6,084,412 shares; 2025Q2: 5,561,359 shares; 2025Q3: 5,681,359 shares; 2025Q4: 6,666,837 shares; 2026Q1: 6,666,837 shares; 2026Q2: 6,666,837 shares 6,666,837$740M6.43%0Timeline
PCVXVAXCYTE INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: 8,689,190 shares; 2024Q4: 8,689,190 shares; 2025Q1: 12,189,149 shares; 2025Q2: 11,965,991 shares; 2025Q3: 11,965,991 shares; 2025Q4: 10,724,599 shares; 2026Q1: 11,474,599 shares; 2026Q2: 11,474,599 shares 11,474,599$667M5.8%0Timeline
SIONSIONNA THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: 10,445,322 shares; 2025Q2: 10,445,322 shares; 2025Q3: 10,445,322 shares; 2025Q4: 9,905,045 shares; 2026Q1: 9,905,045 shares; 2026Q2: 9,905,045 shares 9,905,045$436M3.79%0Timeline
TYRATYRA BIOSCIENCES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: 10,416,609 shares; 2024Q4: 10,637,290 shares; 2025Q1: 10,637,290 shares; 2025Q2: 12,198,625 shares; 2025Q3: 12,198,625 shares; 2025Q4: 12,198,625 shares; 2026Q1: 12,198,625 shares; 2026Q2: 12,198,625 shares 12,198,625$390M3.39%0Timeline
EWTXEDGEWISE THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: 8,909,091 shares; 2024Q4: 8,909,091 shares; 2025Q1: 8,909,091 shares; 2025Q2: 9,902,633 shares; 2025Q3: 10,428,437 shares; 2025Q4: 10,428,437 shares; 2026Q1: 10,428,437 shares; 2026Q2: 8,392,730 shares 8,392,730$341M2.96%-2,035,707Timeline
NAMSNEWAMSTERDAM PHARMA COMPANYQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: 8,064,000 shares; 2024Q4: 8,845,000 shares; 2025Q1: 10,138,938 shares; 2025Q2: 10,138,938 shares; 2025Q3: 10,138,938 shares; 2025Q4: 9,550,191 shares; 2026Q1: 9,550,191 shares; 2026Q2: 9,550,191 shares 9,550,191$324M2.81%0Timeline
COAGHEMAB THERAPEUTICS HLDGS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: not reported; 2026Q1: not reported; 2026Q2: 7,808,627 shares 7,808,627$287M2.49%newTimeline
SEPNSEPTERNA INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: not reported; 2024Q4: 6,995,858 shares; 2025Q1: 6,995,858 shares; 2025Q2: 6,995,858 shares; 2025Q3: 6,995,858 shares; 2025Q4: 6,995,858 shares; 2026Q1: 6,995,858 shares; 2026Q2: 6,995,858 shares 6,995,858$234M2.04%0Timeline
BCAXBICARA THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: 6,955,993 shares; 2024Q4: 6,955,993 shares; 2025Q1: 6,955,993 shares; 2025Q2: 6,955,993 shares; 2025Q3: 6,955,993 shares; 2025Q4: 6,955,993 shares; 2026Q1: 7,255,993 shares; 2026Q2: 7,255,993 shares 7,255,993$215M1.87%0Timeline
MLYSMINERALYS THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: 4,850,984 shares; 2024Q4: 4,850,984 shares; 2025Q1: 6,147,280 shares; 2025Q2: 6,147,280 shares; 2025Q3: 7,323,750 shares; 2025Q4: 7,323,750 shares; 2026Q1: 7,692,750 shares; 2026Q2: 7,692,750 shares 7,692,750$208M1.8%0Timeline
GHRSGH RESEARCH PLCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: 6,686,689 shares; 2024Q4: 6,686,689 shares; 2025Q1: 6,944,648 shares; 2025Q2: 7,676,697 shares; 2025Q3: 7,676,697 shares; 2025Q4: 7,676,697 shares; 2026Q1: 7,676,697 shares; 2026Q2: 7,636,813 shares 7,636,813$205M1.78%-39,884Timeline
IRONDISC MEDICINE INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: 1,577,106 shares; 2025Q2: 1,577,106 shares; 2025Q3: 1,577,106 shares; 2025Q4: 1,976,132 shares; 2026Q1: 2,450,221 shares; 2026Q2: 2,450,221 shares 2,450,221$179M1.56%0Timeline
SGPSPYGLASS PHARMA INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: not reported; 2026Q1: 8,021,117 shares; 2026Q2: 8,021,117 shares 8,021,117$179M1.55%0Timeline
ARTVARTIVA BIOTHERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: 9,853,302 shares; 2024Q4: 9,853,302 shares; 2025Q1: 9,853,302 shares; 2025Q2: 9,853,302 shares; 2025Q3: 9,853,302 shares; 2025Q4: 9,853,302 shares; 2026Q1: 9,853,302 shares; 2026Q2: 17,955,642 shares 17,955,642$174M1.51%+8,102,340Timeline
JANXJANUX THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: 9,165,652 shares; 2024Q4: 10,365,652 shares; 2025Q1: 11,189,693 shares; 2025Q2: 11,189,693 shares; 2025Q3: 11,189,693 shares; 2025Q4: 11,189,693 shares; 2026Q1: 11,189,693 shares; 2026Q2: 11,189,693 shares 11,189,693$172M1.49%0Timeline
TSHATAYSHA GENE THERAPIES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: 10,872,503 shares; 2024Q4: 10,872,503 shares; 2025Q1: 10,872,503 shares; 2025Q2: 23,555,648 shares; 2025Q3: 23,555,648 shares; 2025Q4: 23,555,648 shares; 2026Q1: 23,555,648 shares; 2026Q2: 23,555,648 shares 23,555,648$160M1.39%0Timeline
BCRXBIOCRYST PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 15,827,186 shares; 2026Q1: 15,827,186 shares; 2026Q2: 15,827,186 shares 15,827,186$158M1.38%0Timeline
WVEWAVE LIFE SCIENCES LTDQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: 18,202,009 shares; 2024Q4: 18,202,009 shares; 2025Q1: 18,202,009 shares; 2025Q2: 18,202,009 shares; 2025Q3: 18,202,009 shares; 2025Q4: 18,203,009 shares; 2026Q1: 26,975,505 shares; 2026Q2: 26,975,505 shares 26,975,505$157M1.36%0Timeline
NUVLNUVALENT INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: 176,281 shares; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 1,246,456 shares; 2025Q4: 1,880,057 shares; 2026Q1: 2,534,145 shares; 2026Q2: 1,246,456 shares 1,246,456$154M1.34%-1,287,689Timeline
ABVXABIVAX SAQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: not reported; 2026Q1: not reported; 2026Q2: 1,132,557 shares 1,132,557$151M1.31%newTimeline
ORKAORUKA THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: not reported; 2026Q1: not reported; 2026Q2: 1,554,597 shares 1,554,597$148M1.29%newTimeline
CLYMCLIMB BIO INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: 31,419,267 shares; 2024Q4: 31,419,267 shares; 2025Q1: 31,419,267 shares; 2025Q2: 31,419,267 shares; 2025Q3: 31,419,267 shares; 2025Q4: 11,293,828 shares; 2026Q1: 11,300,939 shares; 2026Q2: 11,300,939 shares 11,300,939$147M1.28%0Timeline
SLDBSOLID BIOSCIENCES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: 4,330,446 shares; 2024Q4: 4,330,446 shares; 2025Q1: 4,330,446 shares; 2025Q2: 5,811,323 shares; 2025Q3: 5,811,423 shares; 2025Q4: 5,811,423 shares; 2026Q1: 9,339,978 shares; 2026Q2: 12,036,126 shares 12,036,126$120M1.04%+2,696,148Timeline
ZLABZAI LAB LTDQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: not reported; 2024Q4: 1,295,040 shares; 2025Q1: 1,295,040 shares; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: not reported; 2026Q1: 5,707,262 shares; 2026Q2: 5,743,533 shares 5,743,533$109M0.95%+36,271Timeline
SPRYARS PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: 10,860,977 shares; 2024Q4: 10,860,977 shares; 2025Q1: 10,860,977 shares; 2025Q2: 10,860,977 shares; 2025Q3: 10,860,977 shares; 2025Q4: 10,860,977 shares; 2026Q1: 10,860,977 shares; 2026Q2: 10,860,977 shares 10,860,977$87M0.76%0Timeline
XNCRXENCOR INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: 575,000 shares; 2024Q4: 575,000 shares; 2025Q1: 575,000 shares; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: not reported; 2026Q1: 4,897,237 shares; 2026Q2: 5,274,274 shares 5,274,274$84.9M0.74%+377,037Timeline
JBIOJADE BIOSCIENCES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 1,062,326 shares; 2025Q3: 1,062,326 shares; 2025Q4: 3,671,083 shares; 2026Q1: 3,671,083 shares; 2026Q2: 3,671,083 shares 3,671,083$81.6M0.71%0Timeline
NTLAINTELLIA THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: not reported; 2026Q1: not reported; 2026Q2: 4,526,926 shares 4,526,926$76.6M0.67%newTimeline
LBRXLB PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 1,776,958 shares; 2025Q4: 2,208,604 shares; 2026Q1: 2,208,604 shares; 2026Q2: 2,208,604 shares 2,208,604$71.7M0.62%0Timeline
DFTXDEFINIUM THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: not reported; 2026Q1: not reported; 2026Q2: 1,500,000 shares 1,500,000$70.6M0.61%newTimeline
ACRSACLARIS THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: not reported; 2024Q4: 4,666,667 shares; 2025Q1: 4,666,667 shares; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: not reported; 2026Q1: 6,804,072 shares; 2026Q2: 12,723,026 shares 12,723,026$67.3M0.58%+5,918,954Timeline
FDMT4D MOLECULAR THERAPEUTICS INQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: 5,098,211 shares; 2024Q4: 4,563,211 shares; 2025Q1: 4,563,211 shares; 2025Q2: 4,563,211 shares; 2025Q3: 4,563,211 shares; 2025Q4: 5,653,211 shares; 2026Q1: 5,049,779 shares; 2026Q2: 5,049,779 shares 5,049,779$67.2M0.58%0Timeline
SANASANA BIOTECHNOLOGY INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: not reported; 2026Q1: not reported; 2026Q2: 18,750,000 shares 18,750,000$65.4M0.57%newTimeline
DMRADAMORA THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: not reported; 2026Q1: 2,399,310 shares; 2026Q2: 2,399,702 shares 2,399,702$62.4M0.54%+392Timeline
MNPRMONOPAR THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: not reported; 2024Q4: 511,207 shares; 2025Q1: 511,207 shares; 2025Q2: 511,207 shares; 2025Q3: 511,207 shares; 2025Q4: 667,207 shares; 2026Q1: 667,207 shares; 2026Q2: 667,207 shares 667,207$61.8M0.54%0Timeline
ABOSACUMEN PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: 14,932,063 shares; 2024Q4: 14,932,063 shares; 2025Q1: 14,932,063 shares; 2025Q2: 14,932,063 shares; 2025Q3: 14,932,063 shares; 2025Q4: 14,932,063 shares; 2026Q1: 20,992,669 shares; 2026Q2: 20,992,669 shares 20,992,669$56.1M0.49%0Timeline
GERNGERON CORPQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: 32,285,755 shares; 2024Q4: 30,009,536 shares; 2025Q1: 60,379,366 shares; 2025Q2: 60,379,366 shares; 2025Q3: 60,379,366 shares; 2025Q4: 63,771,366 shares; 2026Q1: 63,771,366 shares; 2026Q2: 42,809,751 shares 42,809,751$54.8M0.48%-20,961,615Timeline
RZLTREZOLUTE INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 9,180,000 shares; 2026Q1: 9,180,000 shares; 2026Q2: 9,445,039 shares 9,445,039$49.1M0.43%+265,039Timeline
EVMNEVOMMUNE INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 3,458,770 shares; 2026Q1: 3,494,638 shares; 2026Q2: 3,494,638 shares 3,494,638$46.4M0.4%0Timeline
VORVOR BIOPHARMA INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 1,982,301 shares; 2025Q4: 5,404,998 shares; 2026Q1: 5,404,998 shares; 2026Q2: 2,402,095 shares 2,402,095$44.2M0.38%-3,002,903Timeline
IPSCCENTURY THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: not reported; 2026Q1: 17,754,430 shares; 2026Q2: 17,754,430 shares 17,754,430$43.5M0.38%0Timeline
AKTSAKTIS ONCOLOGY INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: not reported; 2026Q1: 1,503,084 shares; 2026Q2: 1,314,405 shares 1,314,405$42.4M0.37%-188,679Timeline
BIOABIOAGE LABS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: 2,210,589 shares; 2024Q4: 1,310,589 shares; 2025Q1: 1,052,494 shares; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: not reported; 2026Q1: 1,650,648 shares; 2026Q2: 1,671,648 shares 1,671,648$41M0.36%+21,000Timeline
CCCCC4 THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: 4,878,000 shares; 2024Q4: 4,878,000 shares; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 8,000,000 shares; 2026Q1: 8,000,000 shares; 2026Q2: 8,000,000 shares 8,000,000$37.4M0.32%0Timeline
MIRMMIRUM PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: not reported; 2026Q1: 318,554 shares; 2026Q2: 318,554 shares 318,554$37.3M0.32%0Timeline
CAPRCAPRICOR THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 1,507,844 shares; 2026Q1: 1,507,844 shares; 2026Q2: 1,507,844 shares 1,507,844$36.3M0.32%0Timeline
PEPGPEPGEN INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: 10,689,545 shares; 2024Q4: 10,689,545 shares; 2025Q1: 10,689,545 shares; 2025Q2: 10,689,545 shares; 2025Q3: 20,064,545 shares; 2025Q4: 20,064,545 shares; 2026Q1: 20,064,545 shares; 2026Q2: 20,064,545 shares 20,064,545$36.1M0.31%0Timeline
PRLDPRELUDE THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: not reported; 2026Q1: not reported; 2026Q2: 6,475,882 shares 6,475,882$34.5M0.3%newTimeline
NKTXNKARTA INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: 10,805,129 shares; 2024Q4: 10,805,129 shares; 2025Q1: 10,805,129 shares; 2025Q2: 10,805,129 shares; 2025Q3: 10,805,129 shares; 2025Q4: 10,805,129 shares; 2026Q1: 10,805,129 shares; 2026Q2: 10,805,129 shares 10,805,129$30.6M0.27%0Timeline
QTTBQ32 BIO INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: not reported; 2026Q1: not reported; 2026Q2: 2,332,457 shares 2,332,457$29.7M0.26%newTimeline
AVRANTERIS TECHNOLOGIES GLOBALQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: not reported; 2026Q1: 3,000,000 shares; 2026Q2: 3,000,000 shares 3,000,000$29.6M0.26%0Timeline
EDITEDITAS MEDICINE INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: not reported; 2026Q1: not reported; 2026Q2: 8,889,000 shares 8,889,000$28.8M0.25%newTimeline
OVIDOVID THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 10,714,000 shares; 2026Q1: 10,714,000 shares; 2026Q2: 10,500,968 shares 10,500,968$28.2M0.25%-213,032Timeline
ASMBASSEMBLY BIOSCIENCES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 1,020,410 shares; 2025Q4: 1,020,410 shares; 2026Q1: 1,020,410 shares; 2026Q2: 1,020,410 shares 1,020,410$28M0.24%0Timeline
ALXOALX ONCOLOGY HLDGS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: not reported; 2026Q1: 13,011,849 shares; 2026Q2: 13,011,849 shares 13,011,849$26.9M0.23%0Timeline
BNTCBENITEC BIOPHARMA INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 1,850,000 shares; 2026Q1: 1,850,000 shares; 2026Q2: 1,850,000 shares 1,850,000$24.8M0.22%0Timeline
LENZLENZ THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: 4,178,823 shares; 2024Q4: 4,178,823 shares; 2025Q1: 4,178,823 shares; 2025Q2: 4,178,823 shares; 2025Q3: 4,178,823 shares; 2025Q4: 4,178,823 shares; 2026Q1: 4,178,823 shares; 2026Q2: 4,178,823 shares 4,178,823$23.7M0.21%0Timeline
LXEOLEXEO THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: 546,554 shares; 2024Q4: 546,554 shares; 2025Q1: 546,554 shares; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 5,000,000 shares; 2026Q1: 5,000,000 shares; 2026Q2: 5,000,000 shares 5,000,000$23.3M0.2%0Timeline
ACRVACRIVON THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: 8,340,508 shares; 2024Q4: 8,340,508 shares; 2025Q1: 8,340,508 shares; 2025Q2: 8,340,508 shares; 2025Q3: 8,340,508 shares; 2025Q4: 8,340,508 shares; 2026Q1: 8,340,508 shares; 2026Q2: 12,229,396 shares 12,229,396$21.8M0.19%+3,888,888Timeline
ALTALTIMMUNE INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: not reported; 2026Q1: not reported; 2026Q2: 6,500,000 shares 6,500,000$19.8M0.17%newTimeline
KPTIKARYOPHARM THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: not reported; 2026Q1: 1,917,354 shares; 2026Q2: 1,917,354 shares 1,917,354$18.7M0.16%0Timeline
DRUGBRIGHT MINDS BIOSCIENCES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: not reported; 2024Q4: 460,829 shares; 2025Q1: 206,427 shares; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: not reported; 2026Q1: 265,000 shares; 2026Q2: 265,000 shares 265,000$18.6M0.16%0Timeline
AVTXAVALO THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: 967,000 shares; 2024Q4: 967,000 shares; 2025Q1: 967,000 shares; 2025Q2: 932,973 shares; 2025Q3: 662,968 shares; 2025Q4: 662,968 shares; 2026Q1: 662,968 shares; 2026Q2: 1,000,000 shares 1,000,000$18.5M0.16%+337,032Timeline
OKURONKURE THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: not reported; 2026Q1: 3,998,333 shares; 2026Q2: 3,998,333 shares 3,998,333$18.2M0.16%0Timeline
FTHFAETH THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: not reported; 2026Q1: not reported; 2026Q2: 722,020 shares 722,020$18.1M0.16%newTimeline
AURAAURA BIOSCIENCES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: not reported; 2026Q1: not reported; 2026Q2: 2,500,000 shares 2,500,000$17.8M0.15%newTimeline
SABSSAB BIOTHERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 4,401,500 shares; 2025Q4: 4,401,500 shares; 2026Q1: 4,401,500 shares; 2026Q2: 4,401,500 shares 4,401,500$17.2M0.15%0Timeline
SPTXSEAPORT THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: not reported; 2026Q1: not reported; 2026Q2: 700,000 shares 700,000$15.2M0.13%newTimeline
PALIPALISADE BIO INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 7,124,116 shares; 2026Q1: 7,124,116 shares; 2026Q2: 7,124,116 shares 7,124,116$14.9M0.13%0Timeline
HLXCHELIX ACQUISITION CORP IIIQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: not reported; 2026Q1: 1,250,000 shares; 2026Q2: 1,250,000 shares 1,250,000$13.3M0.12%0Timeline
WAYWAYSTAR HLDG CORPQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 144,400 shares; 2026Q1: 529,400 shares; 2026Q2: 529,400 shares 529,400$10.9M0.09%0Timeline
EQEQUILLIUM INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: not reported; 2026Q1: 3,096,336 shares; 2026Q2: 3,096,336 shares 3,096,336$9.91M0.09%0Timeline
MGNXMACROGENICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: not reported; 2026Q1: 1,864,176 shares; 2026Q2: 1,864,176 shares 1,864,176$8.61M0.07%0Timeline
FRNMPERCEPTIVE CAP SOLUTIONS CORQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: 750,000 shares; 2024Q4: 750,000 shares; 2025Q1: 750,000 shares; 2025Q2: 750,000 shares; 2025Q3: 750,000 shares; 2025Q4: 750,000 shares; 2026Q1: 750,000 shares; 2026Q2: 750,000 shares 750,000$8.16M0.07%0Timeline
ACETADICET BIO INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 948,249 shares; 2026Q1: 1,182,624 shares; 2026Q2: 932,624 shares 932,624$8.06M0.07%-250,000Timeline
NAMSWNEWAMSTERDAM PHARMA COMPANYQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: 333,333 shares; 2024Q4: 333,333 shares; 2025Q1: 333,333 shares; 2025Q2: 333,333 shares; 2025Q3: 333,333 shares; 2025Q4: 333,333 shares; 2026Q1: 333,333 shares; 2026Q2: 333,333 shares 333,333$7.12M0.06%0Timeline
CRVSCORVUS PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: not reported; 2026Q1: 450,000 shares; 2026Q2: 450,000 shares 450,000$6.72M0.06%0Timeline
RANIRANI THERAPEUTICS HLDGS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 8,500,000 shares; 2026Q1: 8,500,000 shares; 2026Q2: 8,500,000 shares 8,500,000$6.46M0.06%0Timeline
JATTJATT II ACQUISITION CORPQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: not reported; 2026Q1: not reported; 2026Q2: 500,000 shares 500,000$5.68M0.05%newTimeline
AMANAMANAT ACQUISITION CORPQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: not reported; 2026Q1: not reported; 2026Q2: 375,000 shares 375,000$3.81M0.03%newTimeline
HOWLWEREWOLF THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: 6,144,881 shares; 2024Q4: 6,144,881 shares; 2025Q1: 6,144,881 shares; 2025Q2: 6,681,307 shares; 2025Q3: 6,681,307 shares; 2025Q4: 6,681,307 shares; 2026Q1: 6,681,307 shares; 2026Q2: 2,387,744 shares 2,387,744$859K0.01%-4,293,563Timeline
PTNPALATIN TECHNOLOGIES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 70,000 shares; 2026Q1: 70,000 shares; 2026Q2: 62,124 shares 62,124$670K0.01%-7,876Timeline

Sold out in Q2 2026

Positions in the previous quarter's report that this quarter's report no longer lists.

SecurityShares beforeValue beforeType
ASNDASCENDIS PHARMA A/S10,281,496$2.35Bshares
DNTHDIANTHUS THERAPEUTICS INC2,611,733$219Mshares
PRAXPRAXIS PRECISION MEDICINES I373,787$120Mshares
SRPTSAREPTA THERAPEUTICS INC3,902,596$84.9Mshares
SYRESPYRE THERAPEUTICS INC1,621,620$81.8Mshares
FULCFULCRUM THERAPEUTICS INC6,053,960$46.4Mshares
OLMAOLEMA PHARMACEUTICALS INC2,600,000$38.8Mshares
DSGNDESIGN THERAPEUTICS INC2,972,973$31.6Mshares
TVTXTRAVERE THERAPEUTICS INC746,841$22.2Mshares
GRALGRAIL INC428,266$22.1Mshares
RLMDRELMADA THERAPEUTICS INC2,947,369$20.5Mshares
STROSUTRO BIOPHARMA INC715,307$17.8Mshares
CTNMCONTINEUM THERAPEUTICS INC1,296,012$16.9Mshares
INSPINSPIRE MED SYS INC325,663$16.8Mshares
HNGEHINGE HEALTH INC364,613$14.1Mshares
WGSGENEDX HOLDINGS CORP209,887$13.5Mshares
RNAATRIUM THERAPEUTICS INC864,102$11.6Mshares
MPLTMAPLIGHT THERAPEUTICS INC248,294$5.05Mshares

How Q2 2026 was built

Available 13F filings of this filer for the quarter and their roles: the base report is the latest original or restatement, NEW HOLDINGS amendments filed after it are added (method).

FilingRoleAmendmentFiledAcceptedIngested
13F-HR 0001104659-26-097251 base2026-08-14acceptance time not in the bulk data set

Filings

Every filing of this filer: 13F reports and notices, the 13D and 13G it filed or is a reporting person of, and Forms 3, 4 and 5 it reported as an owner.

FilingSubjectFiledAcceptedIngested
Form 4 0001231919-26-001433 Wave Life Sciences, Inc.2026-10-07
Form 4 0001231919-26-001426 Vor Biopharma Inc.2026-10-05
13G 0001346824-26-000243 CRBP2026-09-30
Form 4 0001231919-26-001416 Climb Bio, Inc.2026-09-30
13F-HR 0001104659-26-097251 Quarter ended 2026-06-302026-08-14acceptance time not in the bulk data set
13F-HR 0001104659-26-062637 Quarter ended 2026-03-312026-05-15acceptance time not in the bulk data set
13F-HR 0001104659-26-016482 Quarter ended 2025-12-312026-02-17acceptance time not in the bulk data set
13F-HR 0001104659-25-112469 Quarter ended 2025-09-302025-11-14acceptance time not in the bulk data set
13F-HR 0001104659-25-078691 Quarter ended 2025-06-302025-08-14acceptance time not in the bulk data set
13F-HR 0001104659-25-049549 Quarter ended 2025-03-312025-05-15acceptance time not in the bulk data set
13F-HR 0001104659-25-014181 Quarter ended 2024-12-312025-02-14acceptance time not in the bulk data set
13F-HR 0001104659-24-119034 Quarter ended 2024-09-302024-11-14acceptance time not in the bulk data set
13F-HR 0001104659-24-089629 Quarter ended 2024-06-302024-08-14acceptance time not in the bulk data set
13F-HR/A 0001104659-24-063050 Quarter ended 2024-03-312024-05-17acceptance time not in the bulk data set
13F-HR 0001104659-24-062062 Quarter ended 2024-03-312024-05-15acceptance time not in the bulk data set
13F-HR 0001104659-24-023984 Quarter ended 2023-12-312024-02-14acceptance time not in the bulk data set
13F-HR/A 0001104659-23-118452 Quarter ended 2023-09-302023-11-15acceptance time not in the bulk data set
13F-HR 0001104659-23-118214 Quarter ended 2023-09-302023-11-14acceptance time not in the bulk data set
13F-HR 0001104659-23-091405 Quarter ended 2023-06-302023-08-14acceptance time not in the bulk data set
13F-HR 0001104659-23-060785 Quarter ended 2023-03-312023-05-15acceptance time not in the bulk data set
13F-HR 0001104659-23-021847 Quarter ended 2022-12-312023-02-14acceptance time not in the bulk data set
13F-HR 0001104659-22-118654 Quarter ended 2022-09-302022-11-14acceptance time not in the bulk data set
13F-HR 0001104659-22-091331 Quarter ended 2022-06-302022-08-15acceptance time not in the bulk data set
13F-HR 0001104659-22-061386 Quarter ended 2022-03-312022-05-16acceptance time not in the bulk data set
13F-HR 0001104659-22-022807 Quarter ended 2021-12-312022-02-14acceptance time not in the bulk data set
13F-HR 0001104659-21-139249 Quarter ended 2021-09-302021-11-15acceptance time not in the bulk data set
13F-HR 0001104659-21-106386 Quarter ended 2021-06-302021-08-16acceptance time not in the bulk data set
13F-HR 0001104659-21-068149 Quarter ended 2021-03-312021-05-17acceptance time not in the bulk data set
13F-HR 0001104659-21-024161 Quarter ended 2020-12-312021-02-16acceptance time not in the bulk data set
13F-HR 0001104659-20-125858 Quarter ended 2020-09-302020-11-16acceptance time not in the bulk data set
13F-HR 0001104659-20-095562 Quarter ended 2020-06-302020-08-14acceptance time not in the bulk data set
13F-HR 0001104659-20-062663 Quarter ended 2020-03-312020-05-15acceptance time not in the bulk data set
13F-HR 0001104659-20-021928 Quarter ended 2019-12-312020-02-14acceptance time not in the bulk data set
13F-HR 0001104659-19-064263 Quarter ended 2019-09-302019-11-14acceptance time not in the bulk data set
13F-HR 0001144204-19-040093 Quarter ended 2019-06-302019-08-14acceptance time not in the bulk data set
13F-HR 0001144204-19-026610 Quarter ended 2019-03-312019-05-15acceptance time not in the bulk data set
13F-HR 0001144204-19-008235 Quarter ended 2018-12-312019-02-14acceptance time not in the bulk data set
13F-HR 0001144204-18-059977 Quarter ended 2018-09-302018-11-14acceptance time not in the bulk data set
13F-HR 0001144204-18-044712 Quarter ended 2018-06-302018-08-14acceptance time not in the bulk data set
13F-HR 0001144204-18-028896 Quarter ended 2018-03-312018-05-15acceptance time not in the bulk data set
13F-HR 0001144204-18-008963 Quarter ended 2017-12-312018-02-14acceptance time not in the bulk data set
13F-HR 0001144204-17-059064 Quarter ended 2017-09-302017-11-14acceptance time not in the bulk data set
13F-HR 0001144204-17-043212 Quarter ended 2017-06-302017-08-14acceptance time not in the bulk data set
13F-HR 0001144204-17-027535 Quarter ended 2017-03-312017-05-15acceptance time not in the bulk data set
13F-HR/A 0001144204-17-009568 Quarter ended 2016-12-312017-02-16acceptance time not in the bulk data set
13F-HR/A 0001144204-17-009569 Quarter ended 2016-12-312017-02-16acceptance time not in the bulk data set
13F-HR 0001144204-17-008904 Quarter ended 2016-12-312017-02-14acceptance time not in the bulk data set
13F-HR 0001144204-16-134325 Quarter ended 2016-09-302016-11-14acceptance time not in the bulk data set
13F-HR 0001144204-16-119492 Quarter ended 2016-06-302016-08-15acceptance time not in the bulk data set
13F-HR 0001144204-16-102679 Quarter ended 2016-03-312016-05-16acceptance time not in the bulk data set
13F-HR 0001144204-16-082766 Quarter ended 2015-12-312016-02-16acceptance time not in the bulk data set
13F-HR 0001144204-15-065340 Quarter ended 2015-09-302015-11-13acceptance time not in the bulk data set
13F-HR 0001144204-15-049028 Quarter ended 2015-06-302015-08-13acceptance time not in the bulk data set
13F-HR/A 0001144204-15-041113 Quarter ended 2015-03-312015-07-06acceptance time not in the bulk data set
13F-HR 0001144204-15-031600 Quarter ended 2015-03-312015-05-15acceptance time not in the bulk data set
13F-HR 0001144204-15-010101 Quarter ended 2014-12-312015-02-17acceptance time not in the bulk data set
13F-HR 0001144204-14-068823 Quarter ended 2014-09-302014-11-14acceptance time not in the bulk data set
13F-HR 0001144204-14-050172 Quarter ended 2014-06-302014-08-14acceptance time not in the bulk data set
13F-HR 0001144204-14-031040 Quarter ended 2014-03-312014-05-15acceptance time not in the bulk data set
13F-HR 0001144204-14-009252 Quarter ended 2013-12-312014-02-14acceptance time not in the bulk data set
13F-HR 0001144204-13-061767 Quarter ended 2013-09-302013-11-14acceptance time not in the bulk data set
13F-HR 0001144204-13-045526 Quarter ended 2013-06-302013-08-14acceptance time not in the bulk data set