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Disclosery

SEPN SEPTERNA INC

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Stock (common), issuer CIK 1984086

146 managers (154 13F filers) reported a position in SEPN shares at 2026-06-30, 47,243,280 shares in all. 46 filers opened a position and 16 filers sold out during the quarter.

Managers
146
13F filers
154
New
46
Added
49
Reduced
32
Sold out
16
Shares held by filers
47,243,280

Shares held by filers adds up every 13F filer's report, so a share reported by a parent and by its subsidiary counts twice (H9). Managers counts each filer group once.

13D and 13G filers

No 13D or 13G on this security in the data. Structured 13D/G data starts 2024-12-18.

Insider trades

No Form 4 transaction on this security in the data.

13F holders, Q2 2026

Filers in the available 13F reports with a share position at 2026-06-30, filer groups collapsed to one row (method), largest first. Options and principal amounts are left out. A group row states no % of portfolio, since each member reports its own portfolio: the members' percents are listed under it. A value about 1,000 times or 1/1,000 of the price other filers imply is shown as filed but neither ranks the row nor enters a sum.

HolderSharesValue% of portfolioChangeSource
RA CAPITAL MANAGEMENT, L.P.in group RA CAPITAL MANAGEMENT, L.P.6,995,858$234M2.04%013F-HRTimelineGroup
TRV GP V, LLC6,215,591$208M41.78%013F-HRTimeline
Driehaus Capital Management LLC4,433,058$148M0.86%+37,48613F-HRTimeline
TRV GP VI, LLC4,211,659$141M60.72%013F-HRTimeline
SAMSARA BIOCAPITAL, LLC3,149,128$105M8.66%013F-HRTimeline
GOLDMAN SACHS GROUP INCin group GOLDMAN SACHS GROUP INC3,062,766$103M0.01%+156,33913F-HRTimelineGroup
BlackRock, Inc.in group BlackRock, Inc.1,932,088$64.7M<0.01%+109,91413F-HRTimelineGroup
Siren, L.L.C.in group Siren, L.L.C.1,900,000$63.6M1.29%-100,00013F-HRTimelineGroup
VANGUARD GROUP INCgroup of 6 filers holding1,645,075$55.1M+71,024Timeline
Avoro Capital Advisors LLC1,337,500$44.8M0.4%013F-HRTimeline
Jupiter Topco LLCin group Janus Henderson1,307,500$43.7M0.02%13F-HRTimelineGroup
PRIMECAP MANAGEMENT CO/CA/1,167,382$39.1M0.02%+118,54813F-HRTimeline
First Light Asset Management, LLC963,260$32.3M1.96%+230,40013F-HRTimeline
ADAR1 Capital Management, LLCin group ADAR1 Capital Management, LLC940,747$31.5M1.48%-149,07113F-HRTimelineGroup
GEODE CAPITAL MANAGEMENT, LLCin group GEODE CAPITAL MANAGEMENT, LLC679,163$22.8M<0.01%+34,01713F-HRTimelineGroup
STATE STREET CORPin group STATE STREET CORP652,630$21.9M<0.01%+21,18313F-HRTimelineGroup
LOOMIS SAYLES & CO L Pin group LOOMIS SAYLES & CO L P624,752$20.9M0.03%new13F-HRTimelineGroup
Casdin Capital, LLC553,268$18.5M0.93%013F-HRTimeline
Catalio Capital Management, LP536,152$18M3.37%+241,79213F-HRTimeline
ALGERT GLOBAL LLC397,487$13.3M0.16%+376,45213F-HRTimeline
Balyasny Asset Management L.P.in group Balyasny Asset Management350,442$11.7M0.02%+113,76313F-HRTimelineGroup
Longaeva Partners L.P.298,171$9.99M0.29%+223,60413F-HRTimeline
Soleus Capital Management, L.P.275,000$9.21M0.32%013F-HRTimeline
Universal- Beteiligungs- und Serviceges…in group Universal- Beteiligungs- und …222,702$7.46M0.01%-1,29313F-HRTimelineGroup
TWO SIGMA INVESTMENTS, LPin group TWO SIGMA INVESTMENTS, LP220,885$7.4M0.01%+145,51813F-HRTimelineGroup
NORTHERN TRUST CORPin group NORTHERN TRUST CORP201,131$6.74M<0.01%+36,60113F-HRTimelineGroup
Kalehua Capital Management LLC194,544$6.52M3.75%013F-HR/ATimeline
CHARLES SCHWAB INVESTMENT MANAGEMENT INCin group Charles Schwab Trust Co187,041$6.26M<0.01%+5,46113F-HRTimelineGroup
Woodline Partners LP185,535$6.21M0.02%new13F-HRTimeline
MORGAN STANLEYin group MORGAN STANLEY134,377$4.5M<0.01%+23,84713F-HRTimelineGroup
UBS Group AGgroup of 2 filers holding90,029$3.02M-27,105Timeline
JPMORGAN CHASE & COin group JPMORGAN CHASE & CO85,301$2.96M<0.01%+62713F-HRTimelineGroup
FEDERATED HERMES, INC.in group FEDERATED HERMES, INC.86,753$2.91M<0.01%-2,54813F-HRTimelineGroup
LAZARD ASSET MANAGEMENT LLCin group LAZARD ASSET MANAGEMENT LLC75,425$2.53M<0.01%new13F-HRTimelineGroup
DIMENSIONAL FUND ADVISORS LPin group DIMENSIONAL FUND ADVISORS LP75,309$2.52M<0.01%new13F-HRTimelineGroup
ARROWSTREET CAPITAL, LIMITED PARTNERSHIPin group ARROWSTREET CAPITAL, LIMITED …74,649$2.5M<0.01%new13F-HRTimelineGroup
JACOBS LEVY EQUITY MANAGEMENT, INC68,180$2.28M0.01%+39,74413F-HRTimeline
HUSSMAN STRATEGIC ADVISORS, INC.63,000$2.11M0.49%-42,00013F-HRTimeline
AMERICAN CENTURY COMPANIES INCin group AMERICAN CENTURY COMPANIES INC60,973$2.04M<0.01%-31713F-HRTimelineGroup
Bank of New York Mellon Corpin group Bank of New York Mellon Corp56,176$1.88M<0.01%-2,53313F-HRTimelineGroup
XTX Topco Ltdin group XTX Topco Ltd54,489$1.82M0.02%+17,76613F-HRTimelineGroup
MILLENNIUM MANAGEMENT LLCin group MILLENNIUM MANAGEMENT LLC50,562$1.69M<0.01%-73,53913F-HRTimelineGroup
BARCLAYS PLCin group BARCLAYS PLC49,821$1.67M<0.01%+27,10713F-HRTimelineGroup
Elmind Capital, LP49,444$1.66M0.42%new13F-HRTimeline
Nuveen, LLCin group TIAA48,229$1.62M<0.01%+19,05313F-HRTimelineGroup
Sofinnova Investments, Inc.47,506$1.59M0.08%013F-HRTimeline
D. E. Shaw & Co., Inc.in group D. E. Shaw & Co., Inc.46,483$1.56M<0.01%new13F-HRTimelineGroup
JANE STREET GROUP, LLCin group JANE STREET GROUP, LLC45,552$1.53M<0.01%new13F-HRTimelineGroup
Voleon Capital Management LP44,435$1.49M0.03%new13F-HRTimeline
HRT FINANCIAL LP42,022$1.41M<0.01%new13F-HRTimeline
RENAISSANCE TECHNOLOGIES LLC41,419$1.39M<0.01%+3,71913F-HRTimeline
Russell Investments Group, Ltd.in group Russell Investments Group, Lt…40,209$1.35M<0.01%+28,69413F-HRTimelineGroup
Caption Management, LLC38,006$1.27M0.04%new13F-HRTimeline
BANK OF AMERICA CORP /DE/in group BANK OF AMERICA CORP /DE/35,875$1.2M<0.01%+9,90213F-HRTimelineGroup
PRICE T ROWE ASSOCIATES INC /MD/35,323$1.18M<0.01%+7,24713F-HRTimeline
Alyeska Investment Group, L.P.in group Alyeska Investment Group, L.P.35,000$1.17M<0.01%013F-HRTimelineGroup
Brevan Howard Capital Management LPin group Brevan Howard Capital Managem…29,452$986K0.01%new13F-HRTimelineGroup
HighVista Strategies LLC29,337$982K0.22%new13F-HRTimeline
TUDOR INVESTMENT CORP ET AL28,966$970K<0.01%new13F-HRTimeline
RHUMBLINE ADVISERS27,636$926K<0.01%+1,03213F-HRTimeline
Trexquant Investment LP25,645$859K0.01%-9,65613F-HRTimeline
Invesco Ltd.in group Invesco Ltd.24,094$807K<0.01%-58,77413F-HRTimelineGroup
Logos Global Management LP23,548$789K0.03%013F-HRTimeline
FMR LLCin group FMR LLC23,240$778K<0.01%-20613F-HRTimelineGroup
FOX RUN MANAGEMENT, L.L.C.22,038$738K0.12%new13F-HRTimeline
DEUTSCHE BANK AG\in group DEUTSCHE BANK AG\21,873$733K<0.01%+5,03013F-HRTimelineGroup
ALLIANCEBERNSTEIN L.P.29,900$718K<0.01%+10,30013F-HRTimeline
Squarepoint Ops LLCin group Squarepoint Ops LLC21,219$711K<0.01%+3,13613F-HRTimelineGroup
STRS OHIO21,000$703K<0.01%+3,80013F-HRTimeline
FRED ALGER MANAGEMENT, LLCin group FRED ALGER MANAGEMENT, LLC20,958$702K<0.01%new13F-HRTimelineGroup
ACADIAN ASSET MANAGEMENT LLCin group ACADIAN ASSET MANAGEMENT LLC20,996$701K<0.01%-9,98213F-HRTimelineGroup
Jump Financial, LLCin group Jump Financial, LLC20,200$676K0.01%-32,81113F-HRTimelineGroup
Swiss National Bank19,800$663K<0.01%-2,30013F-HRTimeline
WELLS FARGO & COMPANY/MNin group WELLS FARGO & COMPANY/MN19,684$659K<0.01%+9,81513F-HRTimelineGroup
FRANKLIN RESOURCES INCin group Franklin Resources18,607$623K<0.01%new13F-HRTimelineGroup
CITIGROUP INCin group CITIGROUP INC17,808$596K<0.01%+8,61313F-HRTimelineGroup
Aquatic Capital Management LLC17,427$584K0.02%new13F-HRTimeline
Engineers Gate Manager LP17,350$581K0.01%+82213F-HRTimeline
BNP PARIBAS FINANCIAL MARKETSin group BNP PARIBAS FINANCIAL MARKETS16,946$568K<0.01%+11,58513F-HRTimelineGroup
LOS ANGELES CAPITAL MANAGEMENT LLC16,597$556K<0.01%+2,38313F-HRTimeline
State of Wyoming16,379$549K0.06%new13F-HRTimeline
AQR CAPITAL MANAGEMENT LLCin group AQR CAPITAL MANAGEMENT LLC15,397$516K<0.01%+2213F-HRTimelineGroup
VIRGINIA RETIREMENT SYSTEMS ET Al13,300$445K<0.01%new13F-HRTimeline
Verdad Advisers, LP12,970$434K0.42%new13F-HRTimeline
MetLife Investment Management, LLCin group MetLife Investment Management…12,880$431K<0.01%-80513F-HRTimelineGroup
OSAIC HOLDINGS, INC.in group OSAIC HOLDINGS, INC.12,594$422K<0.01%-10413F-HRTimelineGroup
Mirae Asset Global Investments Co., Ltd.group of 2 filers holding12,209$409K-147Timeline
Man Group plcin group Man Group plc11,469$384K<0.01%-38913F-HRTimelineGroup
CALIFORNIA STATE TEACHERS RETIREMENT SY…10,866$364K<0.01%+9,70913F-HR/ATimeline
China Universal Asset Management Co., L…10,774$361K0.02%-1,17213F-HRTimeline
Legal & General Group Plcin group Legal & General Group Plc10,062$337K<0.01%+4,32713F-HRTimelineGroup
MASSACHUSETTS FINANCIAL SERVICES CO /MA/in group MASSACHUSETTS FINANCIAL SERVI…9,982$334K<0.01%-40013F-HRTimelineGroup
Gotham Asset Management, LLC9,322$312K<0.01%new13F-HRTimeline
Virtus Investment Advisers, LLCin group Virtus Investment Advisers, L…9,102$305K0.07%-1,61713F-HRTimelineGroup
CANADA PENSION PLAN INVESTMENT BOARD8,900$298K<0.01%new13F-HRTimeline
NEW YORK STATE COMMON RETIREMENT FUND8,500$285K<0.01%+2,90013F-HRTimeline
FIRST TRUST ADVISORS LPin group FIRST TRUST ADVISORS LP7,739$259K<0.01%new13F-HRTimelineGroup
Creative Planningin group Creative Planning7,636$256K<0.01%new13F-HRTimelineGroup
Quantinno Capital Management LP7,330$245K<0.01%new13F-HRTimeline
CIBC Bancorp USA Inc.in group CIBC Bancorp USA Inc.7,222$242K<0.01%new13F-HRTimelineGroup
Rangeley Capital, LLC7,200$241K0.22%-32,60013F-HRTimeline
OCCUDO QUANTITATIVE STRATEGIES LP7,191$241K0.01%new13F-HRTimeline
WINTON GROUP Ltdin group WINTON GROUP Ltd7,182$241K0.01%-1,66013F-HRTimelineGroup
Police & Firemen's Retirement System of…6,527$219K<0.01%+1,35213F-HRTimeline
CITADEL ADVISORS LLCin group CITADEL ADVISORS LLC6,350$213K<0.01%new13F-HRTimelineGroup
MANUFACTURERS LIFE INSURANCE COMPANY, T…in group MANUFACTURERS LIFE INSURANCE …6,304$211K<0.01%new13F-HRTimelineGroup
CAPTRUST FINANCIAL ADVISORS6,211$208K<0.01%new13F-HRTimeline
STATE OF WISCONSIN INVESTMENT BOARD6,095$204K<0.01%new13F-HRTimeline
Chung Wu Investment Group, LLC4,800$161K0.11%new13F-HRTimeline
KLP KAPITALFORVALTNING AS2,500$83.7K<0.01%013F-HRTimeline
Covestor Ltd2,123$72K0.04%-13713F-HRTimeline
ROYAL BANK OF CANADAin group ROYAL BANK OF CANADA2,098$70K<0.01%new13F-HRTimelineGroup
Ameritas Investment Partners, Inc.group of 2 filers holding1,962$65.7K+18Timeline
NEW YORK STATE TEACHERS RETIREMENT SYST…1,946$65K<0.01%new13F-HRTimeline
Steward Partners Investment Advisory, L…1,325$44.4K<0.01%new13F-HRTimeline
GAMMA Investing LLC1,119$37.5K<0.01%+913F-HRTimeline
Tower Research Capital LLC (TRC)in group Tower Research Capital LLC (T…1,059$35.5K<0.01%+34213F-HRTimelineGroup
Zurcher Kantonalbank (Zurich Cantonalba…971$32.5K<0.01%+46313F-HRTimeline
SIGNATUREFD, LLC966$32.4K<0.01%013F-HRTimeline
GF FUND MANAGEMENT CO. LTD.950$31.8K<0.01%-5613F-HRTimeline
NISA INVESTMENT ADVISORS, LLC768$25.7K<0.01%-7313F-HRTimeline
Quantbot Technologies LP515$17.2K<0.01%new13F-HRTimeline
Amova Asset Management Americas, Inc.in group Amova Asset Management Americ…507$16.9K<0.01%new13F-HRTimelineGroup
BNP PARIBAS ASSET MANAGEMENT Holding S.…in group BNP PARIBAS ASSET MANAGEMENT …362$12.1K<0.01%new13F-HRTimelineGroup
Pinnacle Wealth Planning Services, Inc.322$10.8K<0.01%013F-HRTimeline
Versant Capital Management, Inc261$8.74K<0.01%013F-HRTimeline
Arax Advisory Partners236$7.9K<0.01%new13F-HRTimeline
US BANCORP \DE\in group US BANCORP \DE\220$7.37K<0.01%+2313F-HRTimelineGroup
Sterling Capital Management LLC200$6.7K<0.01%-51213F-HRTimeline
Larson Financial Group LLC196$6.56K<0.01%-813F-HRTimeline
N.E.W. Advisory Services LLC180$6.03K<0.01%013F-HRTimeline
MassMutual Private Wealth & Trust, FSB104$3.48K<0.01%-3113F-HRTimeline
Aster Capital Management (DIFC) Ltd102$3.42K<0.01%new13F-HR/ATimeline
Caitong International Asset Management …77$2.58K<0.01%+3913F-HRTimeline
EverSource Wealth Advisors, LLCin group EverSource Wealth Advisors, L…64$2.14K<0.01%-413F-HRTimelineGroup
SBI Securities Co., Ltd.55$1.84K<0.01%013F-HRTimeline
Cornerstone Financial Management LLC52$1.74K<0.01%013F-HR/ATimeline
Integrated Wealth Concepts LLC51$1.71K<0.01%new13F-HRTimeline
PNC Financial Services Group, Inc.in group PNC Financial Services Group,…45$1.51K<0.01%+213F-HRTimelineGroup
ROTHSCHILD INVESTMENT LLC30$1K<0.01%013F-HRTimeline
Fortitude Family Office, LLC20$670<0.01%013F-HRTimeline
NATIONAL BANK OF CANADA /FI/in group NATIONAL BANK OF CANADA /FI/7$234<0.01%new13F-HRTimelineGroup
SJS Investment Consulting Inc.6$201<0.01%new13F-HRTimeline
Global Retirement Partners, LLC3$100<0.01%13F-HRTimeline
Allworth Financial LP1$34<0.01%-1613F-HRTimeline
Silver Grove Financial Group, Inc.1$33<0.01%new13F-HRTimeline