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RA CAPITAL MANAGEMENT, L.P.

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13F filer, CIK 1346824, BOSTON, MA

RA CAPITAL MANAGEMENT, L.P. reported $8,115,527,458 across 67 holdings for the quarter ended 2025-09-30, in a 13F-HR filed 2025-11-14. Its ten largest share positions make up 63.91% of the portfolio.

Filed (acceptance time not in the bulk data set), ingested 13F-HR 0001104659-25-112469

Period
2025-09-30
Reported value
$8.12B
Holdings
67
Top 10 weight
63.91%
New
16
Sold out
12

Part of the filer group RA CAPITAL MANAGEMENT, L.P.

How groups are built

Stakes and trades reported after 2025-09-30

13D, 13G and Form 4 filings by this filer's group, dated after the 13F period, on securities the quarter does not hold as shares.

  • WVE WAVE LIFE SCIENCES INC: Form 4 granted 10,700 shares on 2026-10-05, 0001231919-26-001433Timeline
    Accepted , ingested
  • CRBP CORBUS PHARMACEUTICALS HLDGS: 13G 1,914,788 shares, 9.9% of the class, 13G filed 2026-09-30, 0001346824-26-000243Timeline
    Accepted , ingested

Largest buys vs the previous quarter

SecurityShares changeApprox. value
NUVLnew+1,246,456$108M
VORnew+1,982,301$96.6M
BLTEnew+875,000$64.8M
RNAMadded+1,375,000$59.9M
MLYSadded+1,176,470$44.6M

Ranked by the share change valued at this quarter's implied price (value over shares in the 13F). A position sold out is valued at the previous quarter's price, its last report.

Largest sells vs the previous quarter

SecurityShares changeApprox. value
DYNexited-9,714,392-$92.5M
VOR BIOPHARMA INCexited-39,646,039-$64.2M
RXSTexited-3,702,967-$48.1M
Tourmaline Bio Incexited-2,538,925-$40.6M
ELVNexited-848,986-$17M

Ranked by the share change valued at this quarter's implied price (value over shares in the 13F). A position sold out is valued at the previous quarter's price, its last report.

Holdings, Q3 2025

Share positions as resolved from 13F-HR 0001104659-25-112469, largest first. % of portfolio is the value over $8,115,527,458, the sum of the share positions whose value is usable for ratios (method).

SecurityHistorySharesValue% of portfolioChangeLatest eventTimeline
ASNDASCENDIS PHARMA A/SQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 9,710,428 shares; 2024Q4: 10,112,744 shares; 2025Q1: 10,281,496 shares; 2025Q2: 10,281,496 shares; 2025Q3: 10,281,496 shares 10,281,496$2.04B25.19%0Timeline
RYTMRHYTHM PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 6,084,412 shares; 2024Q4: 6,084,412 shares; 2025Q1: 6,084,412 shares; 2025Q2: 5,561,359 shares; 2025Q3: 5,681,359 shares 5,681,359$574M7.07%+120,000Timeline
PCVXVAXCYTE INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 8,689,190 shares; 2024Q4: 8,689,190 shares; 2025Q1: 12,189,149 shares; 2025Q2: 11,965,991 shares; 2025Q3: 11,965,991 shares 11,965,991$431M5.31%0Timeline
RNAMAVIDITY BIOSCIENCES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 6,300,408 shares; 2024Q4: 6,300,408 shares; 2025Q1: 6,300,408 shares; 2025Q2: 7,266,031 shares; 2025Q3: 8,641,031 shares 8,641,031$376M4.64%+1,375,000Timeline
CDTXCIDARA THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 703,080 shares; 2024Q4: 1,092,796 shares; 2025Q1: 1,092,796 shares; 2025Q2: 3,365,523 shares; 2025Q3: 3,365,523 shares 3,365,523$322M3.97%0Timeline
SIONSIONNA THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: 10,445,322 shares; 2025Q2: 10,445,322 shares; 2025Q3: 10,445,322 shares 10,445,322$307M3.79%0Timeline
89BIO INC89BIO INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 14,175,398 shares; 2024Q4: 14,175,398 shares; 2025Q1: 19,889,683 shares; 2025Q2: 19,889,683 shares; 2025Q3: 19,889,683 shares 19,889,683$292M3.6%0
NAMSNEWAMSTERDAM PHARMA COMPANYQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 8,064,000 shares; 2024Q4: 8,845,000 shares; 2025Q1: 10,138,938 shares; 2025Q2: 10,138,938 shares; 2025Q3: 10,138,938 shares 10,138,938$288M3.55%0Timeline
MLYSMINERALYS THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 4,850,984 shares; 2024Q4: 4,850,984 shares; 2025Q1: 6,147,280 shares; 2025Q2: 6,147,280 shares; 2025Q3: 7,323,750 shares 7,323,750$278M3.42%+1,176,470Timeline
JANXJANUX THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 9,165,652 shares; 2024Q4: 10,365,652 shares; 2025Q1: 11,189,693 shares; 2025Q2: 11,189,693 shares; 2025Q3: 11,189,693 shares 11,189,693$273M3.37%0Timeline
ACLXARCELLX INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 1,851,479 shares; 2024Q4: 2,787,327 shares; 2025Q1: 3,036,527 shares; 2025Q2: 3,036,527 shares; 2025Q3: 3,036,527 shares 3,036,527$249M3.07%0Timeline
LENZLENZ THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 4,178,823 shares; 2024Q4: 4,178,823 shares; 2025Q1: 4,178,823 shares; 2025Q2: 4,178,823 shares; 2025Q3: 4,178,823 shares 4,178,823$195M2.4%0Timeline
TYRATYRA BIOSCIENCES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 10,416,609 shares; 2024Q4: 10,637,290 shares; 2025Q1: 10,637,290 shares; 2025Q2: 12,198,625 shares; 2025Q3: 12,198,625 shares 12,198,625$171M2.1%0Timeline
EWTXEDGEWISE THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 8,909,091 shares; 2024Q4: 8,909,091 shares; 2025Q1: 8,909,091 shares; 2025Q2: 9,902,633 shares; 2025Q3: 10,428,437 shares 10,428,437$169M2.08%+525,804Timeline
WVEWAVE LIFE SCIENCES LTDQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 18,202,009 shares; 2024Q4: 18,202,009 shares; 2025Q1: 18,202,009 shares; 2025Q2: 18,202,009 shares; 2025Q3: 18,202,009 shares 18,202,009$133M1.64%0Timeline
SEPNSEPTERNA INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: 6,995,858 shares; 2025Q1: 6,995,858 shares; 2025Q2: 6,995,858 shares; 2025Q3: 6,995,858 shares 6,995,858$132M1.62%0Timeline
DNTHDIANTHUS THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 2,333,000 shares; 2024Q4: 1,866,400 shares; 2025Q1: 2,866,733 shares; 2025Q2: 2,866,733 shares; 2025Q3: 2,866,733 shares 2,866,733$113M1.39%0Timeline
BCAXBICARA THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 6,955,993 shares; 2024Q4: 6,955,993 shares; 2025Q1: 6,955,993 shares; 2025Q2: 6,955,993 shares; 2025Q3: 6,955,993 shares 6,955,993$110M1.35%0Timeline
GHRSGH RESEARCH PLCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 6,686,689 shares; 2024Q4: 6,686,689 shares; 2025Q1: 6,944,648 shares; 2025Q2: 7,676,697 shares; 2025Q3: 7,676,697 shares 7,676,697$110M1.35%0Timeline
SPRYARS PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 10,860,977 shares; 2024Q4: 10,860,977 shares; 2025Q1: 10,860,977 shares; 2025Q2: 10,860,977 shares; 2025Q3: 10,860,977 shares 10,860,977$109M1.34%0Timeline
NUVLNUVALENT INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 176,281 shares; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 1,246,456 shares 1,246,456$108M1.33%newTimeline
IRONDISC MEDICINE INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: 1,577,106 shares; 2025Q2: 1,577,106 shares; 2025Q3: 1,577,106 shares 1,577,106$104M1.28%0Timeline
VORVOR BIOPHARMA INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 1,982,301 shares 1,982,301$96.6M1.19%newTimeline
FULCFULCRUM THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 10,229,099 shares; 2024Q4: 10,229,099 shares; 2025Q1: 10,229,099 shares; 2025Q2: 10,229,099 shares; 2025Q3: 10,229,099 shares 10,229,099$94.1M1.16%0Timeline
PEPGPEPGEN INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 10,689,545 shares; 2024Q4: 10,689,545 shares; 2025Q1: 10,689,545 shares; 2025Q2: 10,689,545 shares; 2025Q3: 20,064,545 shares 20,064,545$92.7M1.14%+9,375,000Timeline
GERNGERON CORPQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 32,285,755 shares; 2024Q4: 30,009,536 shares; 2025Q1: 60,379,366 shares; 2025Q2: 60,379,366 shares; 2025Q3: 60,379,366 shares 60,379,366$82.7M1.02%0Timeline
TSHATAYSHA GENE THERAPIES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 10,872,503 shares; 2024Q4: 10,872,503 shares; 2025Q1: 10,872,503 shares; 2025Q2: 23,555,648 shares; 2025Q3: 23,555,648 shares 23,555,648$77M0.95%0Timeline
BLTEBELITE BIO INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 875,000 shares 875,000$64.8M0.8%newTimeline
CLYMCLIMB BIO INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 31,419,267 shares; 2024Q4: 31,419,267 shares; 2025Q1: 31,419,267 shares; 2025Q2: 31,419,267 shares; 2025Q3: 31,419,267 shares 31,419,267$63.2M0.78%0Timeline
SRRKSCHOLAR ROCK HLDG CORPQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: 17,616 shares; 2025Q1: 1,136,453 shares; 2025Q2: 1,136,453 shares; 2025Q3: 1,166,788 shares 1,166,788$43.5M0.54%+30,335Timeline
GPCRSTRUCTURE THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 1,896,772 shares; 2024Q4: 1,517,418 shares; 2025Q1: 1,517,418 shares; 2025Q2: 1,517,418 shares; 2025Q3: 1,517,418 shares 1,517,418$42.5M0.52%0Timeline
MNPRMONOPAR THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: 511,207 shares; 2025Q1: 511,207 shares; 2025Q2: 511,207 shares; 2025Q3: 511,207 shares 511,207$41.8M0.51%0Timeline
FDMT4D MOLECULAR THERAPEUTICS INQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 5,098,211 shares; 2024Q4: 4,563,211 shares; 2025Q1: 4,563,211 shares; 2025Q2: 4,563,211 shares; 2025Q3: 4,563,211 shares 4,563,211$39.7M0.49%0Timeline
SLDBSOLID BIOSCIENCES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 4,330,446 shares; 2024Q4: 4,330,446 shares; 2025Q1: 4,330,446 shares; 2025Q2: 5,811,323 shares; 2025Q3: 5,811,423 shares 5,811,423$35.9M0.44%+100Timeline
MTSRMETSERA INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: 675,525 shares; 2025Q2: 675,525 shares; 2025Q3: 675,525 shares 675,525$35.4M0.44%0Timeline
ARTVARTIVA BIOTHERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 9,853,302 shares; 2024Q4: 9,853,302 shares; 2025Q1: 9,853,302 shares; 2025Q2: 9,853,302 shares; 2025Q3: 9,853,302 shares 9,853,302$28.3M0.35%0Timeline
LBRXLB PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 1,776,958 shares 1,776,958$28.1M0.35%newTimeline
TVTXTRAVERE THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: 1,150,000 shares; 2025Q1: 1,150,000 shares; 2025Q2: 1,150,000 shares; 2025Q3: 1,150,000 shares 1,150,000$27.5M0.34%0Timeline
ASMBASSEMBLY BIOSCIENCES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 1,020,410 shares 1,020,410$26.1M0.32%newTimeline
ABOSACUMEN PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 14,932,063 shares; 2024Q4: 14,932,063 shares; 2025Q1: 14,932,063 shares; 2025Q2: 14,932,063 shares; 2025Q3: 14,932,063 shares 14,932,063$25.5M0.31%0Timeline
CTNMCONTINEUM THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 2,122,000 shares 2,122,000$24.9M0.31%newTimeline
NKTXNKARTA INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 10,805,129 shares; 2024Q4: 10,805,129 shares; 2025Q1: 10,805,129 shares; 2025Q2: 10,805,129 shares; 2025Q3: 10,805,129 shares 10,805,129$22.4M0.28%0Timeline
LRMRLARIMAR THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 6,045,351 shares; 2024Q4: 6,045,351 shares; 2025Q1: 6,045,351 shares; 2025Q2: 6,045,351 shares; 2025Q3: 6,045,351 shares 6,045,351$19.5M0.24%0Timeline
IVVDINVIVYD INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 17,119,096 shares 17,119,096$18.8M0.23%newTimeline
TNGXTANGO THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 2,000,000 shares; 2025Q3: 2,000,000 shares 2,000,000$16.8M0.21%0Timeline
PRMEPRIME MEDICINE INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 3,000,000 shares 3,000,000$16.6M0.2%newTimeline
RCUSARCUS BIOSCIENCES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: 1,136,364 shares; 2025Q2: 1,136,364 shares; 2025Q3: 1,136,364 shares 1,136,364$15.5M0.19%0Timeline
ACRVACRIVON THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 8,340,508 shares; 2024Q4: 8,340,508 shares; 2025Q1: 8,340,508 shares; 2025Q2: 8,340,508 shares; 2025Q3: 8,340,508 shares 8,340,508$15.1M0.19%0Timeline
HOWLWEREWOLF THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 6,144,881 shares; 2024Q4: 6,144,881 shares; 2025Q1: 6,144,881 shares; 2025Q2: 6,681,307 shares; 2025Q3: 6,681,307 shares 6,681,307$13.2M0.16%0Timeline
QUREUNIQURE NVQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 200,000 shares 200,000$11.7M0.14%newTimeline
ELDNELEDON PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: 3,566,338 shares; 2025Q1: 3,566,338 shares; 2025Q2: 3,566,338 shares; 2025Q3: 3,566,338 shares 3,566,338$9.24M0.11%0Timeline
JBIOJADE BIOSCIENCES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 1,062,326 shares; 2025Q3: 1,062,326 shares 1,062,326$9.17M0.11%0Timeline
SABSSAB BIOTHERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 4,401,500 shares 4,401,500$8.85M0.11%newTimeline
INSPINSPIRE MED SYS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 114,901 shares 114,901$8.53M0.11%newTimeline
CTMXCYTOMX THERAPEUTICS INC.Quarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: 1,000,000 shares; 2025Q2: 2,661,331 shares; 2025Q3: 2,661,331 shares 2,661,331$8.49M0.1%0Timeline
AVTXAVALO THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 967,000 shares; 2024Q4: 967,000 shares; 2025Q1: 967,000 shares; 2025Q2: 932,973 shares; 2025Q3: 662,968 shares 662,968$8.43M0.1%-270,005Timeline
FRNMPERCEPTIVE CAP SOLUTIONS CORQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 750,000 shares; 2024Q4: 750,000 shares; 2025Q1: 750,000 shares; 2025Q2: 750,000 shares; 2025Q3: 750,000 shares 750,000$7.95M0.1%0Timeline
SRZNSURROZEN INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 282,580 shares; 2024Q4: 282,580 shares; 2025Q1: 679,130 shares; 2025Q2: 602,626 shares; 2025Q3: 602,626 shares 602,626$7.76M0.1%0Timeline
WGSGENEDX HOLDINGS CORPQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 58,044 shares; 2025Q3: 58,044 shares 58,044$6.25M0.08%0Timeline
ADICET BIO INCADICET BIO INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 7,541,000 shares; 2024Q4: 7,541,000 shares; 2025Q1: 7,541,000 shares; 2025Q2: 7,541,000 shares; 2025Q3: 7,541,000 shares 7,541,000$6.11M0.08%0
NAMSWNEWAMSTERDAM PHARMA COMPANYQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 333,333 shares; 2024Q4: 333,333 shares; 2025Q1: 333,333 shares; 2025Q2: 333,333 shares; 2025Q3: 333,333 shares 333,333$5.7M0.07%0Timeline
EVHEVOLENT HEALTH INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 8,514,862 shares; 2024Q4: 3,577,197 shares; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 579,052 shares 579,052$4.9M0.06%newTimeline
GKOSGLAUKOS CORPQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: 190,256 shares; 2025Q2: not reported; 2025Q3: 54,180 shares 54,180$4.42M0.05%newTimeline
DSGNDESIGN THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 475,699 shares 475,699$3.58M0.04%newTimeline
EXASEXACT SCIENCES CORPQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 54,939 shares 54,939$3.01M0.04%newTimeline
IFRXINFLARX NVQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 1,973,233 shares; 2025Q3: 1,973,233 shares 1,973,233$2.64M0.03%0Timeline
PGNYPROGYNY INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 96,628 shares 96,628$2.08M0.03%newTimeline

Sold out in Q3 2025

Positions in the previous quarter's report that this quarter's report no longer lists.

SecurityShares beforeValue beforeType
DYNDYNE THERAPEUTICS INC9,714,392$92.5Mshares
VOR BIOPHARMA INCVOR BIOPHARMA INC39,646,039$64.2Mshares
RXSTRXSIGHT INC3,702,967$48.1Mshares
Tourmaline Bio IncTourmaline Bio Inc2,538,925$40.6Mshares
ELVNENLIVEN THERAPEUTICS INC848,986$17Mshares
HNGEHINGE HEALTH INC300,000$15.5Mshares
OMDAOMADA HEALTH INC400,000$7.32Mshares
BBNXBETA BIONICS INC500,000$7.28Mshares
TXG10X GENOMICS INC475,343$5.5Mshares
MBXMBX BIOSCIENCES INC377,841$4.31Mshares
TARAPROTARA THERAPEUTICS INC1,039,295$3.15Mshares
ACHCACADIA HEALTHCARE COMPANY IN89,262$2.03Mshares

How Q3 2025 was built

Available 13F filings of this filer for the quarter and their roles: the base report is the latest original or restatement, NEW HOLDINGS amendments filed after it are added (method).

FilingRoleAmendmentFiledAcceptedIngested
13F-HR 0001104659-25-112469 base2025-11-14acceptance time not in the bulk data set