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Disclosery

ORKA ORUKA THERAPEUTICS INC

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Stock (common), issuer CIK 907654

247 managers (257 13F filers) reported a position in ORKA shares at 2026-06-30, 74,134,303 shares in all. 97 filers opened a position and 27 filers sold out during the quarter.

Managers
247
13F filers
257
New
97
Added
94
Reduced
46
Sold out
27
Shares held by filers
74,134,303

Shares held by filers adds up every 13F filer's report, so a share reported by a parent and by its subsidiary counts twice (H9). Managers counts each filer group once.

13D and 13G filers

No 13D or 13G on this security in the data. Structured 13D/G data starts 2024-12-18.

Insider trades

No Form 4 transaction on this security in the data.

13F holders, Q2 2026

Filers in the available 13F reports with a share position at 2026-06-30, filer groups collapsed to one row (method), largest first. Options and principal amounts are left out. A group row states no % of portfolio, since each member reports its own portfolio: the members' percents are listed under it. A value about 1,000 times or 1/1,000 of the price other filers imply is shown as filed but neither ranks the row nor enters a sum.

HolderSharesValue% of portfolioChangeSource
FMR LLCin group FMR LLC9,057,645$862M0.04%+1,626,24213F-HRTimelineGroup
BlackRock, Inc.in group BlackRock, Inc.4,990,181$475M0.01%+1,463,09413F-HRTimelineGroup
Venrock Adviser, LLC4,148,428$395M11.97%013F-HRTimeline
Fairmount Funds Management LLC3,705,262$353M23.31%013F-HRTimeline
Capital World Investors3,401,639$324M0.04%new13F-HRTimeline
VANGUARD GROUP INCgroup of 7 filers holding3,366,890$320M+857,481Timeline
RTW INVESTMENTS, LP3,139,030$299M2.55%+1,080,88213F-HRTimeline
STATE STREET CORPin group STATE STREET CORP2,673,090$254M0.01%+1,059,62913F-HRTimelineGroup
Paradigm Biocapital Advisors LPin group Paradigm Biocapital Advisors …2,144,526$204M3.82%-175,79013F-HRTimelineGroup
Deep Track Capital, LP1,926,000$183M2.7%-108,20313F-HRTimeline
Bellevue Group AGin group Bellevue Group AG1,657,190$158M3.32%+1,150,18213F-HRTimelineGroup
FRANKLIN RESOURCES INCin group Franklin Resources1,621,451$154M0.03%+617,39513F-HRTimelineGroup
Remedium Capital Partners, LLC1,565,661$149M32.99%013F-HRTimeline
RA CAPITAL MANAGEMENT, L.P.in group RA CAPITAL MANAGEMENT, L.P.1,554,597$148M1.29%new13F-HRTimelineGroup
VIKING GLOBAL INVESTORS LPin group VIKING GLOBAL INVESTORS LP1,503,478$143M0.41%-1,163,21213F-HRTimelineGroup
GEODE CAPITAL MANAGEMENT, LLCin group GEODE CAPITAL MANAGEMENT, LLC1,429,954$136M0.01%+475,08713F-HRTimelineGroup
Jupiter Topco LLCin group Janus Henderson1,375,844$131M0.05%13F-HRTimelineGroup
PERCEPTIVE ADVISORS LLCin group PERCEPTIVE ADVISORS LLC1,345,063$128M1.99%-50,43813F-HRTimelineGroup
Polar Capital Holdings Plcin group Polar Capital Holdings Plc1,228,609$117M0.33%+180,91613F-HRTimelineGroup
CITADEL ADVISORS LLCin group CITADEL ADVISORS LLC1,119,011$106M0.06%+111,47413F-HRTimelineGroup
T. Rowe Price Investment Management, In…1,103,743$105M0.07%new13F-HRTimeline
BNP PARIBAS FINANCIAL MARKETSin group BNP PARIBAS FINANCIAL MARKETS1,079,015$103M0.05%+1,068,08713F-HRTimelineGroup
PRICE T ROWE ASSOCIATES INC /MD/838,603$79.8M0.01%+111,15413F-HRTimeline
Avidity Partners Management LP760,424$72.4M11.59%013F-HRTimeline
UBS Group AGgroup of 2 filers holding743,673$70.8M+514,500Timeline
SUMMIT PARTNERS PUBLIC ASSET MANAGEMENT…in group SUMMIT PARTNERS PUBLIC ASSET …658,301$62.7M1.63%new13F-HRTimelineGroup
Aberdeen Group plcin group Aberdeen Group plc646,943$61.6M0.09%+571,26313F-HRTimelineGroup
JPMORGAN CHASE & COin group JPMORGAN CHASE & CO655,027$60.7M<0.01%+632,40713F-HRTimelineGroup
WESTFIELD CAPITAL MANAGEMENT CO LP631,433$60.1M0.2%+318,30313F-HRTimeline
Pictet Asset Management Holding SAin group Pictet Asset Management Holdi…619,076$58.9M0.06%new13F-HRTimelineGroup
Affinity Asset Advisors, LLC590,000$56.2M2.75%+90,32713F-HRTimeline
Cormorant Asset Management, LP533,340$50.8M2.6%013F-HRTimeline
CHARLES SCHWAB INVESTMENT MANAGEMENT INCin group Charles Schwab Trust Co433,405$41.2M0.01%+111,45613F-HRTimelineGroup
NORTHERN TRUST CORPin group NORTHERN TRUST CORP428,891$40.8M<0.01%+129,84713F-HRTimelineGroup
VOYA INVESTMENT MANAGEMENT LLCin group VOYA INVESTMENT MANAGEMENT LLC401,149$38.2M0.03%+334,54913F-HRTimelineGroup
LORD, ABBETT & CO. LLC390,064$37.1M0.11%new13F-HRTimeline
MASSACHUSETTS FINANCIAL SERVICES CO /MA/in group MASSACHUSETTS FINANCIAL SERVI…364,102$34.7M0.01%new13F-HRTimelineGroup
Synergy Asset Management, LLCin group Synergy Asset Management, LLC356,301$33.9M3.2%-119,89513F-HRTimelineGroup
ADAGE CAPITAL PARTNERS GP, L.L.C.in group ADAGE CAPITAL PARTNERS GP, L.…355,003$33.8M0.05%+164,97313F-HRTimelineGroup
BANK OF AMERICA CORP /DE/in group BANK OF AMERICA CORP /DE/352,824$33.6M<0.01%+252,73313F-HRTimelineGroup
SILVERARC CAPITAL MANAGEMENT, LLCin group SILVERARC CAPITAL MANAGEMENT,…352,802$33.6M3.74%+201,89413F-HRTimelineGroup
Candriam S.C.A.352,716$33.5M0.15%-58,29013F-HRTimeline
Holocene Advisors, LP305,951$29.1M0.07%+120,43813F-HRTimeline
JENNISON ASSOCIATES LLC299,257$28.5M0.02%+122,57713F-HRTimeline
Woodline Partners LP285,247$27.1M0.08%-289,63513F-HRTimeline
BRAIDWELL LP278,164$26.5M0.98%new13F-HRTimeline
Siren, L.L.C.in group Siren, L.L.C.250,000$23.8M0.48%new13F-HRTimelineGroup
Nuveen, LLCin group TIAA249,267$23.7M0.01%+162,32913F-HRTimelineGroup
EVENTIDE ASSET MANAGEMENT, LLC240,000$22.8M0.31%new13F-HRTimeline
Blackstone Inc.in group Blackstone Inc.237,108$22.6M0.07%new13F-HRTimelineGroupThe filing omitted confidential holdings, a later amendment may add them.
NOMURA ASSET MANAGEMENT CO LTDgroup of 2 filers holding219,039$20.8MnewTimeline
SEB Asset Management AB196,753$18.7M0.07%new13F-HRTimeline
DEUTSCHE BANK AG\in group DEUTSCHE BANK AG\195,204$18.6M0.01%+54,41513F-HRTimelineGroup
GREAT POINT PARTNERS LLC183,330$17.4M4.11%013F-HRTimeline
GOLDMAN SACHS GROUP INCin group GOLDMAN SACHS GROUP INC179,439$17.1M<0.01%-67,27213F-HRTimelineGroup
Sio Capital Management, LLC177,118$16.9M2.89%+44,62213F-HRTimeline
Handelsbanken Fonder AB160,900$15.3M0.04%new13F-HRTimeline
PFM Health Sciences, LP158,825$15.1M1.31%-15,22713F-HRTimeline
First Turn Management, LLC155,343$14.8M1.58%new13F-HRTimeline
ExodusPoint Capital Management, LP148,212$14.1M0.13%+46,85813F-HRTimeline
Bank of New York Mellon Corpin group Bank of New York Mellon Corp140,870$13.4M<0.01%+33,98713F-HRTimelineGroup
Invesco Ltd.in group Invesco Ltd.124,658$11.9M<0.01%+27,61613F-HRTimelineGroup
VICTORY CAPITAL MANAGEMENT INC124,278$11.8M0.01%+119,60013F-HRTimeline
WELLINGTON MANAGEMENT GROUP LLPin group WELLINGTON MANAGEMENT GROUP L…119,601$11.4M<0.01%-1,62413F-HRTimelineGroup
STEMPOINT CAPITAL LP116,461$11.1M1.92%new13F-HRTimeline
Parkman Healthcare Partners LLC113,188$10.8M1.11%new13F-HRTimeline
DIMENSIONAL FUND ADVISORS LPin group DIMENSIONAL FUND ADVISORS LP113,176$10.8M<0.01%+16713F-HRTimelineGroup
Russell Investments Group, Ltd.in group Russell Investments Group, Lt…112,943$10.7M0.01%+67,48413F-HRTimelineGroup
Apis Capital Advisors, LLC112,000$10.7M1.04%new13F-HRTimeline
SEVEN GRAND MANAGERS, LLC110,000$10.5M0.42%new13F-HRTimeline
KENNEDY CAPITAL MANAGEMENT LLC106,863$10.2M0.18%-19,50313F-HRTimeline
TD Asset Management Inc102,944$9.8M0.01%+27,24813F-HRTimeline
Moody Aldrich Partners LLC101,411$9.65M1.73%-33,65013F-HRTimeline
Atika Capital Management LLCin group Atika Capital Management LLC100,000$9.52M0.94%-129,90013F-HRTimelineGroup
TORONTO DOMINION BANKin group TORONTO DOMINION BANK89,837$8.55M0.01%new13F-HRTimelineGroup
Alyeska Investment Group, L.P.in group Alyeska Investment Group, L.P.87,744$8.35M0.02%-97,11913F-HRTimelineGroup
PRUDENTIAL FINANCIAL INCin group PRUDENTIAL FINANCIAL INC85,895$8.17M0.01%+79,85513F-HRTimelineGroup
Rhenman & Partners Asset Management AB80,000$7.61M0.72%new13F-HRTimeline
MORGAN STANLEYin group MORGAN STANLEY76,360$7.27M<0.01%-99,09413F-HRTimelineGroup
B Group, Inc.75,000$7.14M4.05%013F-HRTimeline
BARCLAYS PLCin group BARCLAYS PLC74,762$7.12M<0.01%-10,97513F-HRTimelineGroup
AMERIPRISE FINANCIAL INCin group AMERIPRISE FINANCIAL INC72,734$6.92M<0.01%new13F-HRTimelineGroup
MANUFACTURERS LIFE INSURANCE COMPANY, T…in group MANUFACTURERS LIFE INSURANCE …68,421$6.51M0.01%-4,14213F-HRTimelineGroup
Fisher Asset Management, LLC67,874$6.46M<0.01%new13F-HRTimeline
Ensign Peak Advisors, Inc67,668$6.44M0.01%-11,71213F-HRTimeline
CITIGROUP INCin group CITIGROUP INC67,101$6.39M<0.01%+56,71413F-HRTimelineGroup
Secure Asset Management, LLC65,899$6.27M0.88%-6,52313F-HRTimeline
Swiss National Bank63,000$6M<0.01%+20,00013F-HRTimeline
ALPS ADVISORS INC61,014$5.81M0.03%+21,61013F-HRTimeline
RHUMBLINE ADVISERS60,784$5.78M<0.01%+14,42813F-HRTimeline
Informed Momentum Co LLC59,014$5.62M0.5%-93213F-HRTimeline
Atle Fund Management AB54,886$5.22M1.41%new13F-HRTimeline
WELLS FARGO & COMPANY/MNin group WELLS FARGO & COMPANY/MN51,924$4.94M<0.01%+37,09313F-HRTimelineGroup
Granahan Investment Management, LLC51,038$4.86M0.17%new13F-HRTimeline
Ghisallo Capital Management LLC50,000$4.76M0.09%new13F-HRTimeline
Burkehill Global Management, LP50,000$4.76M0.17%new13F-HRTimeline
Trexquant Investment LP49,616$4.72M0.03%new13F-HRTimeline
Rafferty Asset Management, LLC43,110$4.1M0.01%+2,62313F-HRTimeline
SECTORAL ASSET MANAGEMENT INC41,987$4M2.79%new13F-HRTimeline
HighVista Strategies LLC41,902$3.99M0.91%-37,00913F-HRTimeline
XTX Topco Ltdin group XTX Topco Ltd40,506$3.85M0.05%+20,32613F-HRTimelineGroup
PRINCIPAL FINANCIAL GROUP INCin group PRINCIPAL FINANCIAL GROUP INC39,776$3.79M<0.01%new13F-HRTimelineGroup
CALIFORNIA STATE TEACHERS RETIREMENT SY…36,020$3.43M<0.01%+14,65013F-HR/ATimeline
Schonfeld Strategic Advisors LLC34,860$3.32M0.02%new13F-HRTimeline
ALLIANCEBERNSTEIN L.P.66,080$3.24M<0.01%+25,68013F-HRTimeline
Palo Alto Investors LP33,546$3.19M0.44%-26,43913F-HR/ATimeline
Artia Global Partners LP33,400$3.18M0.6%new13F-HRTimeline
MILLENNIUM MANAGEMENT LLCin group MILLENNIUM MANAGEMENT LLC32,866$3.13M<0.01%new13F-HRTimelineGroup
LAZARD ASSET MANAGEMENT LLCin group LAZARD ASSET MANAGEMENT LLC32,191$3.06M<0.01%new13F-HRTimelineGroup
Mirae Asset Global Investments Co., Ltd.group of 2 filers holding30,901$2.93M+7,412Timeline
Legal & General Group Plcin group Legal & General Group Plc30,198$2.87M<0.01%+14,28013F-HRTimelineGroup
FEDERATED HERMES, INC.in group FEDERATED HERMES, INC.30,082$2.86M<0.01%new13F-HRTimelineGroup
MetLife Investment Management, LLCin group MetLife Investment Management…29,313$2.79M0.01%+7,95013F-HRTimelineGroup
Harvest Investment Services, LLC29,063$2.77M0.43%new13F-HRTimeline
DIADEMA PARTNERS LP27,799$2.65M0.93%new13F-HRTimeline
MUTUAL OF AMERICA CAPITAL MANAGEMENT LLCin group MUTUAL OF AMERICA CAPITAL MAN…27,733$2.64M0.03%new13F-HRTimelineGroup
DZ BANK AG Deutsche Zentral Genossensch…in group DZ BANK AG Deutsche Zentral G…27,694$2.64M<0.01%new13F-HRTimelineGroup
MARTINGALE ASSET MANAGEMENT L P26,727$2.54M0.06%-16,00513F-HRTimeline
JUPITER ASSET MANAGEMENT LTDin group JUPITER ASSET MANAGEMENT LTD25,236$2.4M0.01%new13F-HRTimelineGroup
Freestone Grove Partners LP22,421$2.13M0.01%new13F-HRTimeline
GLENMEDE TRUST CO NAin group GLENMEDE TRUST CO NA22,096$2.1M0.01%+32413F-HRTimelineGroup
PROFUND ADVISORS LLC22,012$2.09M0.06%+3,67613F-HRTimeline
SCHRODER INVESTMENT MANAGEMENT GROUP21,453$1.98M<0.01%-7,73113F-HRTimeline
ADAR1 Capital Management, LLCin group ADAR1 Capital Management, LLC20,840$1.98M0.09%013F-HRTimelineGroup
STATE OF WISCONSIN INVESTMENT BOARD19,561$1.86M<0.01%+1,46213F-HRTimeline
Empirical Financial Services, LLC d.b.a…19,312$1.84M0.03%+1,08313F-HRTimeline
ENVESTNET ASSET MANAGEMENT INCin group ENVESTNET ASSET MANAGEMENT INC18,857$1.79M<0.01%-4,81013F-HRTimelineGroup
AQR CAPITAL MANAGEMENT LLCin group AQR CAPITAL MANAGEMENT LLC18,697$1.78M<0.01%+14,49013F-HRTimelineGroup
NEW YORK STATE COMMON RETIREMENT FUND17,700$1.68M<0.01%+5,50013F-HRTimeline
SEI INVESTMENTS COin group SEI INVESTMENTS CO16,758$1.59M<0.01%-6,08213F-HRTimelineGroup
Creative Planningin group Creative Planning15,738$1.5M<0.01%+3,00213F-HRTimelineGroup
Atom Investors LP15,521$1.48M0.13%new13F-HRTimeline
LPL Financial LLC15,231$1.45M<0.01%new13F-HRTimeline
Police & Firemen's Retirement System of…14,857$1.41M0.01%+4,65013F-HRTimeline
SG Americas Securities, LLC14,576$1.39M<0.01%new13F-HRTimeline
AXXCESS WEALTH MANAGEMENT, LLC14,515$1.38M0.02%new13F-HRTimeline
OPTIMIZE FINANCIAL INC.13,396$1.27M0.46%-4613F-HRTimeline
Sound Capital Solutions LLC13,396$1.27M0.3%13F-HRTimeline
Brookwood Investment Group LLC12,990$1.24M0.14%-3,00313F-HRTimeline
J. Goldman & Co LP12,356$1.18M0.04%new13F-HRTimeline
STATE BOARD OF ADMINISTRATION OF FLORID…12,149$1.16M<0.01%+5,46213F-HRTimeline
Rock Springs Capital Management LP12,051$1.15M0.06%+7,92813F-HRTimeline
INTECH INVESTMENT MANAGEMENT LLC11,763$1.12M0.01%+10313F-HRTimeline
Balyasny Asset Management L.P.in group Balyasny Asset Management11,586$1.1M<0.01%new13F-HRTimelineGroup
ROYAL BANK OF CANADAin group ROYAL BANK OF CANADA11,123$1.06M<0.01%+7,95113F-HRTimelineGroup
State of New Jersey Common Pension Fund…in group State of New Jersey Common Pe…10,161$967K<0.01%+2,72013F-HRTimelineGroup
Mariner, LLCin group Mariner, LLC10,022$954K<0.01%new13F-HRTimelineGroup
STRS OHIO9,800$933K<0.01%new13F-HRTimeline
Zurcher Kantonalbank (Zurich Cantonalba…9,600$914K<0.01%+9,10413F-HRTimeline
China Universal Asset Management Co., L…9,599$914K0.05%+1,00813F-HRTimeline
Virtus Investment Advisers, LLCgroup of 2 filers holding9,407$895K+373Timeline
STIFEL FINANCIAL CORPin group STIFEL FINANCIAL CORP9,176$873K<0.01%+3,02013F-HRTimelineGroup
Advisory Services Network, LLC8,860$843K0.01%-1,94013F-HRTimeline
ARIZONA STATE RETIREMENT SYSTEM8,671$825K<0.01%+2,69113F-HRTimeline
ProShare Advisors LLC8,570$816K<0.01%+81413F-HRTimeline
Virtu Financial LLCin group Virtu Financial LLC8,456$805K0.03%new13F-HRTimelineGroup
KLP KAPITALFORVALTNING AS8,000$761K<0.01%013F-HRTimeline
Stonepine Capital Management, LLC7,500$714K0.54%new13F-HR/ATimeline
Fieldview Capital Management, LLC7,104$676K0.19%new13F-HRTimeline
Persistent Asset Partners Ltd7,085$674K0.21%new13F-HRTimeline
AlphaCentric Advisors LLC6,531$622K0.53%-4,97513F-HRTimeline
Quantinno Capital Management LP6,401$609K<0.01%+1,22513F-HRTimeline
Arrowpoint Investment Partners (Singapo…in group Arrowpoint Investment Partner…6,315$601K0.18%+1,16813F-HRTimelineGroup
DNB Asset Management ASin group DNB Asset Management AS6,129$583K<0.01%new13F-HRTimelineGroup
E Fund Management Co., Ltd.6,079$579K0.01%+98913F-HRTimeline
Orion Porfolio Solutions, LLC5,825$554K<0.01%-1,40413F-HRTimeline
MML INVESTORS SERVICES, LLC5,801$552K<0.01%-47613F-HRTimeline
ALGERT GLOBAL LLC5,380$512K0.01%+18013F-HRTimeline
AMERICAN CENTURY COMPANIES INCin group AMERICAN CENTURY COMPANIES INC4,948$471K<0.01%-69,43813F-HRTimelineGroup
XPONANCE LLC4,927$469K<0.01%new13F-HRTimeline
Quantbot Technologies LP4,870$463K0.02%new13F-HRTimeline
FIRST TRUST ADVISORS LPin group FIRST TRUST ADVISORS LP4,663$444K<0.01%new13F-HRTimelineGroup
SUSQUEHANNA INTERNATIONAL GROUP, LLPin group SUSQUEHANNA INTERNATIONAL GRO…4,588$437K<0.01%-16,39613F-HRTimelineGroup
Ameritas Investment Partners, Inc.group of 2 filers holding4,572$435K+1,429Timeline
Ground Swell Capital, LLC4,320$411K0.44%new13F-HRTimeline
Quadrature Capital Ltdin group Quadrature Capital Ltd4,290$408K<0.01%new13F-HRTimelineGroup
PNC Financial Services Group, Inc.in group PNC Financial Services Group,…4,225$402K<0.01%+1,03913F-HRTimelineGroup
US BANCORP \DE\in group US BANCORP \DE\4,194$399K<0.01%-67113F-HRTimelineGroup
Allspring Global Investments Holdings, …in group Allspring Global Investments …3,823$357K<0.01%new13F-HRTimelineGroup
Engineers Gate Manager LP3,680$350K<0.01%new13F-HRTimeline
Allianz Asset Management GmbHin group Allianz SE7,100$348K<0.01%013F-HRTimelineGroup
TEACHER RETIREMENT SYSTEM OF TEXAS3,643$347K<0.01%new13F-HRTimeline
Voleon Capital Management LP3,557$339K0.01%-36,98213F-HRTimeline
Belvedere Trading LLC3,531$336K0.03%new13F-HRTimeline
Focus Partners Wealthin group Focus Partners Wealth3,500$333K<0.01%new13F-HRTimelineGroup
PSP Research LLC3,000$286K0.15%-1,96813F-HRTimeline
Ethic Inc.2,965$282K<0.01%new13F-HRTimeline
Gradient Investments LLCin group Gradient Investments LLC2,868$273K<0.01%new13F-HRTimelineGroup
CIBC Bancorp USA Inc.in group CIBC Bancorp USA Inc.2,827$269K<0.01%new13F-HRTimelineGroup
Universal- Beteiligungs- und Serviceges…in group Universal- Beteiligungs- und …2,789$265K<0.01%new13F-HRTimelineGroup
Iron Gate Global Advisors LLC2,750$262K0.03%new13F-HRTimeline
Mitsubishi UFJ Trust & Banking Corpin group Mitsubishi UFJ Trust & Bankin…2,642$251K<0.01%new13F-HRTimelineGroup
COMMONWEALTH EQUITY SERVICES, LLC2,332$222K<0.01%new13F-HRTimeline
FOX RUN MANAGEMENT, L.L.C.2,247$214K0.04%new13F-HRTimeline
State of Wyoming2,242$213K0.02%new13F-HRTimeline
Connor, Clark & Lunn Investment Managem…2,215$211K<0.01%new13F-HRTimeline
NEUBERGER BERMAN GROUP LLCin group NEUBERGER BERMAN GROUP LLC2,210$210K<0.01%new13F-HRTimelineGroup
NATURAL INVESTMENTS, LLC2,125$202K0.04%new13F-HRTimeline
Swiss Life Asset Management Ltdin group Swiss Life Asset Management L…2,122$202K<0.01%new13F-HRTimelineGroup
Tower Research Capital LLC (TRC)in group Tower Research Capital LLC (T…1,933$184K<0.01%-1,51613F-HRTimelineGroup