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RA CAPITAL MANAGEMENT, L.P.

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13F filer, CIK 1346824, BOSTON, MA

RA CAPITAL MANAGEMENT, L.P. reported $9,437,744,027 across 85 holdings for the quarter ended 2026-03-31, in a 13F-HR filed 2026-05-15. Its ten largest share positions make up 61.29% of the portfolio.

Filed (acceptance time not in the bulk data set), ingested 13F-HR 0001104659-26-062637

Period
2026-03-31
Reported value
$9.44B
Holdings
85
Top 10 weight
61.29%
New
24
Sold out
10

Part of the filer group RA CAPITAL MANAGEMENT, L.P.

How groups are built

Stakes and trades reported after 2026-03-31

13D, 13G and Form 4 filings by this filer's group, dated after the 13F period, on securities the quarter does not hold as shares.

  • WVE WAVE LIFE SCIENCES INC: Form 4 granted 10,700 shares on 2026-10-05, 0001231919-26-001433Timeline
    Accepted , ingested
  • CRBP CORBUS PHARMACEUTICALS HLDGS: 13G 1,914,788 shares, 9.9% of the class, 13G filed 2026-09-30, 0001346824-26-000243Timeline
    Accepted , ingested

Largest buys vs the previous quarter

SecurityShares changeApprox. value
SGPnew+8,021,117$208M
ZLABnew+5,707,262$107M
SRPTnew+3,902,596$84.9M
DNTHadded+1,000,000$83.9M
NUVLadded+654,088$67M

Ranked by the share change valued at this quarter's implied price (value over shares in the 13F). A position sold out is valued at the previous quarter's price, its last report.

Largest sells vs the previous quarter

SecurityShares changeApprox. value
CDTXexited-3,365,523-$743M
RNAMexited-8,641,031-$623M
ACLXexited-1,267,156-$82.6M
BLTEexited-432,484-$69.2M
IVVDexited-17,119,096-$42.3M

Ranked by the share change valued at this quarter's implied price (value over shares in the 13F). A position sold out is valued at the previous quarter's price, its last report.

Holdings, Q1 2026

Share positions as resolved from 13F-HR 0001104659-26-062637, largest first. % of portfolio is the value over $9,437,744,027, the sum of the share positions whose value is usable for ratios (method).

SecurityHistorySharesValue% of portfolioChangeLatest eventTimeline
ASNDASCENDIS PHARMA A/SQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: 9,710,428 shares; 2024Q4: 10,112,744 shares; 2025Q1: 10,281,496 shares; 2025Q2: 10,281,496 shares; 2025Q3: 10,281,496 shares; 2025Q4: 10,281,496 shares; 2026Q1: 10,281,496 shares 10,281,496$2.35B24.92%0Timeline
PCVXVAXCYTE INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: 8,689,190 shares; 2024Q4: 8,689,190 shares; 2025Q1: 12,189,149 shares; 2025Q2: 11,965,991 shares; 2025Q3: 11,965,991 shares; 2025Q4: 10,724,599 shares; 2026Q1: 11,474,599 shares 11,474,599$667M7.07%+750,000Timeline
RYTMRHYTHM PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: 6,084,412 shares; 2024Q4: 6,084,412 shares; 2025Q1: 6,084,412 shares; 2025Q2: 5,561,359 shares; 2025Q3: 5,681,359 shares; 2025Q4: 6,666,837 shares; 2026Q1: 6,666,837 shares 6,666,837$580M6.14%0Timeline
TYRATYRA BIOSCIENCES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: 10,416,609 shares; 2024Q4: 10,637,290 shares; 2025Q1: 10,637,290 shares; 2025Q2: 12,198,625 shares; 2025Q3: 12,198,625 shares; 2025Q4: 12,198,625 shares; 2026Q1: 12,198,625 shares 12,198,625$467M4.95%0Timeline
SIONSIONNA THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: 10,445,322 shares; 2025Q2: 10,445,322 shares; 2025Q3: 10,445,322 shares; 2025Q4: 9,905,045 shares; 2026Q1: 9,905,045 shares 9,905,045$397M4.21%0Timeline
EWTXEDGEWISE THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: 8,909,091 shares; 2024Q4: 8,909,091 shares; 2025Q1: 8,909,091 shares; 2025Q2: 9,902,633 shares; 2025Q3: 10,428,437 shares; 2025Q4: 10,428,437 shares; 2026Q1: 10,428,437 shares 10,428,437$328M3.48%0Timeline
NAMSNEWAMSTERDAM PHARMA COMPANYQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: 8,064,000 shares; 2024Q4: 8,845,000 shares; 2025Q1: 10,138,938 shares; 2025Q2: 10,138,938 shares; 2025Q3: 10,138,938 shares; 2025Q4: 9,550,191 shares; 2026Q1: 9,550,191 shares 9,550,191$306M3.24%0Timeline
NUVLNUVALENT INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: 176,281 shares; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 1,246,456 shares; 2025Q4: 1,880,057 shares; 2026Q1: 2,534,145 shares 2,534,145$260M2.75%+654,088Timeline
DNTHDIANTHUS THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: 2,333,000 shares; 2024Q4: 1,866,400 shares; 2025Q1: 2,866,733 shares; 2025Q2: 2,866,733 shares; 2025Q3: 2,866,733 shares; 2025Q4: 1,611,733 shares; 2026Q1: 2,611,733 shares 2,611,733$219M2.32%+1,000,000Timeline
MLYSMINERALYS THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: 4,850,984 shares; 2024Q4: 4,850,984 shares; 2025Q1: 6,147,280 shares; 2025Q2: 6,147,280 shares; 2025Q3: 7,323,750 shares; 2025Q4: 7,323,750 shares; 2026Q1: 7,692,750 shares 7,692,750$208M2.21%+369,000Timeline
SGPSPYGLASS PHARMA INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: not reported; 2026Q1: 8,021,117 shares 8,021,117$208M2.2%newTimeline
WVEWAVE LIFE SCIENCES LTDQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: 18,202,009 shares; 2024Q4: 18,202,009 shares; 2025Q1: 18,202,009 shares; 2025Q2: 18,202,009 shares; 2025Q3: 18,202,009 shares; 2025Q4: 18,203,009 shares; 2026Q1: 26,975,505 shares 26,975,505$196M2.07%+8,772,496Timeline
SEPNSEPTERNA INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: 6,995,858 shares; 2025Q1: 6,995,858 shares; 2025Q2: 6,995,858 shares; 2025Q3: 6,995,858 shares; 2025Q4: 6,995,858 shares; 2026Q1: 6,995,858 shares 6,995,858$168M1.78%0Timeline
IRONDISC MEDICINE INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: 1,577,106 shares; 2025Q2: 1,577,106 shares; 2025Q3: 1,577,106 shares; 2025Q4: 1,976,132 shares; 2026Q1: 2,450,221 shares 2,450,221$157M1.66%+474,089Timeline
JANXJANUX THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: 9,165,652 shares; 2024Q4: 10,365,652 shares; 2025Q1: 11,189,693 shares; 2025Q2: 11,189,693 shares; 2025Q3: 11,189,693 shares; 2025Q4: 11,189,693 shares; 2026Q1: 11,189,693 shares 11,189,693$156M1.65%0Timeline
BCRXBIOCRYST PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 15,827,186 shares; 2026Q1: 15,827,186 shares 15,827,186$151M1.6%0Timeline
BCAXBICARA THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: 6,955,993 shares; 2024Q4: 6,955,993 shares; 2025Q1: 6,955,993 shares; 2025Q2: 6,955,993 shares; 2025Q3: 6,955,993 shares; 2025Q4: 6,955,993 shares; 2026Q1: 7,255,993 shares 7,255,993$144M1.53%+300,000Timeline
PRAXPRAXIS PRECISION MEDICINES IQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: 761,955 shares; 2024Q4: 761,955 shares; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 373,787 shares; 2026Q1: 373,787 shares 373,787$120M1.28%0Timeline
GHRSGH RESEARCH PLCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: 6,686,689 shares; 2024Q4: 6,686,689 shares; 2025Q1: 6,944,648 shares; 2025Q2: 7,676,697 shares; 2025Q3: 7,676,697 shares; 2025Q4: 7,676,697 shares; 2026Q1: 7,676,697 shares 7,676,697$108M1.14%0Timeline
ZLABZAI LAB LTDQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: 1,295,040 shares; 2025Q1: 1,295,040 shares; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: not reported; 2026Q1: 5,707,262 shares 5,707,262$107M1.14%newTimeline
TSHATAYSHA GENE THERAPIES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: 10,872,503 shares; 2024Q4: 10,872,503 shares; 2025Q1: 10,872,503 shares; 2025Q2: 23,555,648 shares; 2025Q3: 23,555,648 shares; 2025Q4: 23,555,648 shares; 2026Q1: 23,555,648 shares 23,555,648$105M1.12%0Timeline
VORVOR BIOPHARMA INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 1,982,301 shares; 2025Q4: 5,404,998 shares; 2026Q1: 5,404,998 shares 5,404,998$96.4M1.02%0Timeline
GERNGERON CORPQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: 32,285,755 shares; 2024Q4: 30,009,536 shares; 2025Q1: 60,379,366 shares; 2025Q2: 60,379,366 shares; 2025Q3: 60,379,366 shares; 2025Q4: 63,771,366 shares; 2026Q1: 63,771,366 shares 63,771,366$95M1.01%0Timeline
SPRYARS PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: 10,860,977 shares; 2024Q4: 10,860,977 shares; 2025Q1: 10,860,977 shares; 2025Q2: 10,860,977 shares; 2025Q3: 10,860,977 shares; 2025Q4: 10,860,977 shares; 2026Q1: 10,860,977 shares 10,860,977$87.2M0.92%0Timeline
SRPTSAREPTA THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: not reported; 2026Q1: 3,902,596 shares 3,902,596$84.9M0.9%newTimeline
SYRESPYRE THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 1,621,620 shares; 2026Q1: 1,621,620 shares 1,621,620$81.8M0.87%0Timeline
EVMNEVOMMUNE INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 3,458,770 shares; 2026Q1: 3,494,638 shares 3,494,638$80.3M0.85%+35,868Timeline
CLYMCLIMB BIO INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: 31,419,267 shares; 2024Q4: 31,419,267 shares; 2025Q1: 31,419,267 shares; 2025Q2: 31,419,267 shares; 2025Q3: 31,419,267 shares; 2025Q4: 11,293,828 shares; 2026Q1: 11,300,939 shares 11,300,939$77.4M0.82%+7,111Timeline
SLDBSOLID BIOSCIENCES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: 4,330,446 shares; 2024Q4: 4,330,446 shares; 2025Q1: 4,330,446 shares; 2025Q2: 5,811,323 shares; 2025Q3: 5,811,423 shares; 2025Q4: 5,811,423 shares; 2026Q1: 9,339,978 shares 9,339,978$67.2M0.71%+3,528,555Timeline
ARTVARTIVA BIOTHERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: 9,853,302 shares; 2024Q4: 9,853,302 shares; 2025Q1: 9,853,302 shares; 2025Q2: 9,853,302 shares; 2025Q3: 9,853,302 shares; 2025Q4: 9,853,302 shares; 2026Q1: 9,853,302 shares 9,853,302$63.5M0.67%0Timeline
DMRADAMORA THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: not reported; 2026Q1: 2,399,310 shares 2,399,310$62.1M0.66%newTimeline
XNCRXENCOR INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: 575,000 shares; 2024Q4: 575,000 shares; 2025Q1: 575,000 shares; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: not reported; 2026Q1: 4,897,237 shares 4,897,237$59.1M0.63%newTimeline
LBRXLB PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 1,776,958 shares; 2025Q4: 2,208,604 shares; 2026Q1: 2,208,604 shares 2,208,604$54.5M0.58%0Timeline
JBIOJADE BIOSCIENCES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 1,062,326 shares; 2025Q3: 1,062,326 shares; 2025Q4: 3,671,083 shares; 2026Q1: 3,671,083 shares 3,671,083$51.6M0.55%0Timeline
ABOSACUMEN PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: 14,932,063 shares; 2024Q4: 14,932,063 shares; 2025Q1: 14,932,063 shares; 2025Q2: 14,932,063 shares; 2025Q3: 14,932,063 shares; 2025Q4: 14,932,063 shares; 2026Q1: 20,992,669 shares 20,992,669$49.5M0.52%+6,060,606Timeline
FDMT4D MOLECULAR THERAPEUTICS INQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: 5,098,211 shares; 2024Q4: 4,563,211 shares; 2025Q1: 4,563,211 shares; 2025Q2: 4,563,211 shares; 2025Q3: 4,563,211 shares; 2025Q4: 5,653,211 shares; 2026Q1: 5,049,779 shares 5,049,779$47M0.5%-603,432Timeline
FULCFULCRUM THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: 10,229,099 shares; 2024Q4: 10,229,099 shares; 2025Q1: 10,229,099 shares; 2025Q2: 10,229,099 shares; 2025Q3: 10,229,099 shares; 2025Q4: 6,053,960 shares; 2026Q1: 6,053,960 shares 6,053,960$46.4M0.49%0Timeline
CAPRCAPRICOR THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 1,507,844 shares; 2026Q1: 1,507,844 shares 1,507,844$45.8M0.49%0Timeline
IPSCCENTURY THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: not reported; 2026Q1: 17,754,430 shares 17,754,430$40.1M0.43%newTimeline
OLMAOLEMA PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 2,600,000 shares; 2026Q1: 2,600,000 shares 2,600,000$38.8M0.41%0Timeline
LENZLENZ THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: 4,178,823 shares; 2024Q4: 4,178,823 shares; 2025Q1: 4,178,823 shares; 2025Q2: 4,178,823 shares; 2025Q3: 4,178,823 shares; 2025Q4: 4,178,823 shares; 2026Q1: 4,178,823 shares 4,178,823$38.2M0.41%0Timeline
MNPRMONOPAR THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: 511,207 shares; 2025Q1: 511,207 shares; 2025Q2: 511,207 shares; 2025Q3: 511,207 shares; 2025Q4: 667,207 shares; 2026Q1: 667,207 shares 667,207$36.6M0.39%0Timeline
PEPGPEPGEN INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: 10,689,545 shares; 2024Q4: 10,689,545 shares; 2025Q1: 10,689,545 shares; 2025Q2: 10,689,545 shares; 2025Q3: 20,064,545 shares; 2025Q4: 20,064,545 shares; 2026Q1: 20,064,545 shares 20,064,545$35.5M0.38%0Timeline
DSGNDESIGN THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 475,699 shares; 2025Q4: 1,461,381 shares; 2026Q1: 2,972,973 shares 2,972,973$31.6M0.34%+1,511,592Timeline
MIRMMIRUM PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: not reported; 2026Q1: 318,554 shares 318,554$29.4M0.31%newTimeline
BIOABIOAGE LABS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: 2,210,589 shares; 2024Q4: 1,310,589 shares; 2025Q1: 1,052,494 shares; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: not reported; 2026Q1: 1,650,648 shares 1,650,648$28.9M0.31%newTimeline
LXEOLEXEO THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: 546,554 shares; 2024Q4: 546,554 shares; 2025Q1: 546,554 shares; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 5,000,000 shares; 2026Q1: 5,000,000 shares 5,000,000$28.7M0.3%0Timeline
ASMBASSEMBLY BIOSCIENCES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 1,020,410 shares; 2025Q4: 1,020,410 shares; 2026Q1: 1,020,410 shares 1,020,410$28.3M0.3%0Timeline
RZLTREZOLUTE INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 9,180,000 shares; 2026Q1: 9,180,000 shares 9,180,000$28M0.3%0Timeline
AKTSAKTIS ONCOLOGY INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: not reported; 2026Q1: 1,503,084 shares 1,503,084$26.9M0.28%newTimeline
ALXOALX ONCOLOGY HLDGS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: not reported; 2026Q1: 13,011,849 shares 13,011,849$26.1M0.28%newTimeline
ACRSACLARIS THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: 4,666,667 shares; 2025Q1: 4,666,667 shares; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: not reported; 2026Q1: 6,804,072 shares 6,804,072$25.5M0.27%newTimeline
OVIDOVID THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 10,714,000 shares; 2026Q1: 10,714,000 shares 10,714,000$23.8M0.25%0Timeline
NKTXNKARTA INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: 10,805,129 shares; 2024Q4: 10,805,129 shares; 2025Q1: 10,805,129 shares; 2025Q2: 10,805,129 shares; 2025Q3: 10,805,129 shares; 2025Q4: 10,805,129 shares; 2026Q1: 10,805,129 shares 10,805,129$22.8M0.24%0Timeline
TVTXTRAVERE THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: 1,150,000 shares; 2025Q1: 1,150,000 shares; 2025Q2: 1,150,000 shares; 2025Q3: 1,150,000 shares; 2025Q4: not reported; 2026Q1: 746,841 shares 746,841$22.2M0.24%newTimeline
GRALGRAIL INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 428,266 shares; 2026Q1: 428,266 shares 428,266$22.1M0.23%0Timeline
CCCCC4 THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: 4,878,000 shares; 2024Q4: 4,878,000 shares; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 8,000,000 shares; 2026Q1: 8,000,000 shares 8,000,000$21M0.22%0Timeline
RLMDRELMADA THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: not reported; 2026Q1: 2,947,369 shares 2,947,369$20.5M0.22%newTimeline
BNTCBENITEC BIOPHARMA INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 1,850,000 shares; 2026Q1: 1,850,000 shares 1,850,000$19.7M0.21%0Timeline
DRUGBRIGHT MINDS BIOSCIENCES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: 460,829 shares; 2025Q1: 206,427 shares; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: not reported; 2026Q1: 265,000 shares 265,000$19.3M0.2%newTimeline
STROSUTRO BIOPHARMA INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: not reported; 2026Q1: 715,307 shares 715,307$17.8M0.19%newTimeline
CTNMCONTINEUM THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 2,122,000 shares; 2025Q4: 2,179,711 shares; 2026Q1: 1,296,012 shares 1,296,012$16.9M0.18%-883,699Timeline
SABSSAB BIOTHERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 4,401,500 shares; 2025Q4: 4,401,500 shares; 2026Q1: 4,401,500 shares 4,401,500$16.9M0.18%0Timeline
INSPINSPIRE MED SYS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 114,901 shares; 2025Q4: 141,964 shares; 2026Q1: 325,663 shares 325,663$16.8M0.18%+183,699Timeline
AVRANTERIS TECHNOLOGIES GLOBALQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: not reported; 2026Q1: 3,000,000 shares 3,000,000$16.6M0.18%newTimeline
OKURONKURE THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: not reported; 2026Q1: 3,998,333 shares 3,998,333$16.6M0.18%newTimeline
HNGEHINGE HEALTH INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 300,000 shares; 2025Q3: not reported; 2025Q4: 80,113 shares; 2026Q1: 364,613 shares 364,613$14.1M0.15%+284,500Timeline
WGSGENEDX HOLDINGS CORPQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 58,044 shares; 2025Q3: 58,044 shares; 2025Q4: 58,044 shares; 2026Q1: 209,887 shares 209,887$13.5M0.14%+151,843Timeline
WAYWAYSTAR HLDG CORPQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 144,400 shares; 2026Q1: 529,400 shares 529,400$12.8M0.14%+385,000Timeline
HLXCHELIX ACQUISITION CORP IIIQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: not reported; 2026Q1: 1,250,000 shares 1,250,000$12.7M0.13%newTimeline
PALIPALISADE BIO INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 7,124,116 shares; 2026Q1: 7,124,116 shares 7,124,116$12.5M0.13%0Timeline
ACRVACRIVON THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: 8,340,508 shares; 2024Q4: 8,340,508 shares; 2025Q1: 8,340,508 shares; 2025Q2: 8,340,508 shares; 2025Q3: 8,340,508 shares; 2025Q4: 8,340,508 shares; 2026Q1: 8,340,508 shares 8,340,508$11.6M0.12%0Timeline
RNAATRIUM THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: not reported; 2026Q1: 864,102 shares 864,102$11.6M0.12%newTimeline
KPTIKARYOPHARM THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: not reported; 2026Q1: 1,917,354 shares 1,917,354$10.7M0.11%newTimeline
AVTXAVALO THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: 967,000 shares; 2024Q4: 967,000 shares; 2025Q1: 967,000 shares; 2025Q2: 932,973 shares; 2025Q3: 662,968 shares; 2025Q4: 662,968 shares; 2026Q1: 662,968 shares 662,968$9.9M0.1%0Timeline
FRNMPERCEPTIVE CAP SOLUTIONS CORQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: 750,000 shares; 2024Q4: 750,000 shares; 2025Q1: 750,000 shares; 2025Q2: 750,000 shares; 2025Q3: 750,000 shares; 2025Q4: 750,000 shares; 2026Q1: 750,000 shares 750,000$8.23M0.09%0Timeline
ACETADICET BIO INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 948,249 shares; 2026Q1: 1,182,624 shares 1,182,624$8.05M0.09%+234,375Timeline
NAMSWNEWAMSTERDAM PHARMA COMPANYQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: 333,333 shares; 2024Q4: 333,333 shares; 2025Q1: 333,333 shares; 2025Q2: 333,333 shares; 2025Q3: 333,333 shares; 2025Q4: 333,333 shares; 2026Q1: 333,333 shares 333,333$6.68M0.07%0Timeline
CRVSCORVUS PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: not reported; 2026Q1: 450,000 shares 450,000$6.58M0.07%newTimeline
RANIRANI THERAPEUTICS HLDGS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 8,500,000 shares; 2026Q1: 8,500,000 shares 8,500,000$6.25M0.07%0Timeline
EQEQUILLIUM INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: not reported; 2026Q1: 3,096,336 shares 3,096,336$6.19M0.07%newTimeline
HOWLWEREWOLF THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: 6,144,881 shares; 2024Q4: 6,144,881 shares; 2025Q1: 6,144,881 shares; 2025Q2: 6,681,307 shares; 2025Q3: 6,681,307 shares; 2025Q4: 6,681,307 shares; 2026Q1: 6,681,307 shares 6,681,307$5.56M0.06%0Timeline
MGNXMACROGENICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: not reported; 2026Q1: 1,864,176 shares 1,864,176$5.39M0.06%newTimeline
MPLTMAPLIGHT THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: not reported; 2026Q1: 248,294 shares 248,294$5.05M0.05%newTimeline
PTNPALATIN TECHNOLOGIES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 70,000 shares; 2026Q1: 70,000 shares 70,000$1.22M0.01%0Timeline

Sold out in Q1 2026

Positions in the previous quarter's report that this quarter's report no longer lists.

SecurityShares beforeValue beforeType
CDTXCIDARA THERAPEUTICS INC3,365,523$743Mshares
RNAMAVIDITY BIOSCIENCES INC8,641,031$623Mshares
ACLXARCELLX INC1,267,156$82.6Mshares
BLTEBELITE BIO INC432,484$69.2Mshares
IVVDINVIVYD INC17,119,096$42.3Mshares
MDLNMEDLINE INC335,000$14.1Mshares
PGNYPROGYNY INC96,628$2.48Mshares
QIAGEN N.V.QIAGEN N.V.43,976$2.08Mshares
KIDSORTHOPEDIATRICS CORP109,959$1.95Mshares
HCATHEALTH CATALYST INC793,749$1.9Mshares

How Q1 2026 was built

Available 13F filings of this filer for the quarter and their roles: the base report is the latest original or restatement, NEW HOLDINGS amendments filed after it are added (method).

FilingRoleAmendmentFiledAcceptedIngested
13F-HR 0001104659-26-062637 base2026-05-15acceptance time not in the bulk data set