RA CAPITAL MANAGEMENT, L.P. in group RA CAPITAL MANAGEMENT, L.P. More: the full row for RA CAPITAL MANAGEMENT, L.P. 28,933,371 $792M 6.88% new 13F-HR Timeline Group FMR LLC in group FMR LLC More: the full row for FMR LLC 10,292,735 $282M 0.01% new 13F-HR Timeline Group ARCH Venture Management, LLC More: the full row for ARCH Venture Management, LLC 6,412,780 $176M 15.95% new 13F-HR Timeline venBio Partners LLC More: the full row for venBio Partners LLC 5,266,697 $144M 27.75% new 13F-HR Timeline Alphabet Inc. in group Alphabet Inc. More: the full row for Alphabet Inc. 4,919,498 $135M 0.14% new 13F-HR Timeline Group Nextech Invest Ltd. More: the full row for Nextech Invest Ltd. 4,663,176 $128M 6.06% new 13F-HR Timeline Cormorant Asset Management, LP More: the full row for Cormorant Asset Management, LP 4,615,612 $126M 6.47% new 13F-HR Timeline REGENERON PHARMACEUTICALS, INC. More: the full row for REGENERON PHARMACEUTICALS, INC. 4,166,666 $114M 64.35% new 13F-HR Timeline Siren, L.L.C. in group Siren, L.L.C. More: the full row for Siren, L.L.C. 2,992,259 $81.9M 1.66% new 13F-HR Timeline Group VANGUARD GROUP INC group of 4 filers holding More: the full row for VANGUARD GROUP INC 2,498,970 $68.4M new Timeline FARALLON CAPITAL MANAGEMENT, L.L.C. More: the full row for FARALLON CAPITAL MANAGEMENT, L.L.C. 2,368,200 $64.8M 0.38% new 13F-HR Timeline Jupiter Topco LLC in group Janus Henderson More: the full row for Jupiter Topco LLC 2,296,547 $62.7M 0.03% 13F-HR Timeline Group Frazier Life Sciences Management, L.P. More: the full row for Frazier Life Sciences Management, L.P. 1,920,805 $52.6M 1.14% new 13F-HR Timeline DEERFIELD MANAGEMENT COMPANY, L.P. in group DEERFIELD MANAGEMENT COMPANY,… More: the full row for DEERFIELD MANAGEMENT COMPANY, L.P. 1,880,704 $51.5M 0.54% new 13F-HR Timeline Group General Catalyst Group Management, LLC More: the full row for General Catalyst Group Management, LLC 1,600,937 $43.8M 23.24% new 13F-HR Timeline GENERAL ATLANTIC, L.P. More: the full row for GENERAL ATLANTIC, L.P. 1,538,461 $42.1M 1.45% new 13F-HR Timeline Soleus Capital Management, L.P. More: the full row for Soleus Capital Management, L.P. 1,465,070 $40.1M 1.38% new 13F-HR Timeline JPMORGAN CHASE & CO in group JPMORGAN CHASE & CO More: the full row for JPMORGAN CHASE & CO 1,042,772 $30.4M <0.01% new 13F-HR Timeline Group Foresite Capital Management VI LLC in group Foresite Capital Management V… More: the full row for Foresite Capital Management VI LLC 999,044 $27.3M 4.26% new 13F-HR Timeline Group Catalio Capital Management, LP More: the full row for Catalio Capital Management, LP 824,043 $22.6M 4.24% new 13F-HR Timeline ALLIANCEBERNSTEIN L.P. More: the full row for ALLIANCEBERNSTEIN L.P. 810,279 $22.2M 0.01% new 13F-HR Timeline PRICE T ROWE ASSOCIATES INC /MD/ More: the full row for PRICE T ROWE ASSOCIATES INC /MD/ 751,947 $20.6M <0.01% new 13F-HR Timeline Casdin Capital, LLC More: the full row for Casdin Capital, LLC 645,690 $17.7M 0.88% new 13F-HR Timeline Venrock Adviser, LLC More: the full row for Venrock Adviser, LLC 625,000 $17.1M 0.52% new 13F-HR Timeline Rock Springs Capital Management LP More: the full row for Rock Springs Capital Management LP 578,028 $15.8M 0.77% new 13F-HR Timeline SAMSARA BIOCAPITAL, LLC More: the full row for SAMSARA BIOCAPITAL, LLC 556,044 $15.2M 1.25% new 13F-HR Timeline Logos Global Management LP More: the full row for Logos Global Management LP 525,000 $14.4M 0.62% new 13F-HR Timeline BAKER BROS. ADVISORS LP in group BAKER BROS. ADVISORS LP More: the full row for BAKER BROS. ADVISORS LP 500,000 $13.7M 0.07% new 13F-HR Timeline Group Bellevue Group AG in group Bellevue Group AG More: the full row for Bellevue Group AG 500,000 $13.7M 0.29% new 13F-HR Timeline Group MARSHALL WACE, LLP in group MARSHALL WACE, LLP More: the full row for MARSHALL WACE, LLP 445,359 $12.2M 0.01% new 13F-HR Timeline Group FRANKLIN RESOURCES INC in group Franklin Resources More: the full row for FRANKLIN RESOURCES INC 381,487 $10.4M <0.01% new 13F-HR Timeline Group ICONIQ Capital, LLC in group ICONIQ Capital, LLC More: the full row for ICONIQ Capital, LLC 350,000 $9.58M 0.28% new 13F-HR Timeline Group MASSACHUSETTS FINANCIAL SERVICES CO /MA/ in group MASSACHUSETTS FINANCIAL SERVI… More: the full row for MASSACHUSETTS FINANCIAL SERVICES CO /MA/ 295,962 $8.1M <0.01% new 13F-HR Timeline Group Kynam Capital Management, LP More: the full row for Kynam Capital Management, LP 250,000 $6.84M 0.38% new 13F-HR Timeline FEDERATED HERMES, INC. in group FEDERATED HERMES, INC. More: the full row for FEDERATED HERMES, INC. 246,200 $6.74M 0.01% new 13F-HR Timeline Group AMERIPRISE FINANCIAL INC in group AMERIPRISE FINANCIAL INC More: the full row for AMERIPRISE FINANCIAL INC 174,773 $4.78M <0.01% new 13F-HR Timeline Group Driehaus Capital Management LLC More: the full row for Driehaus Capital Management LLC 100,000 $2.74M 0.02% new 13F-HR Timeline GEODE CAPITAL MANAGEMENT, LLC in group GEODE CAPITAL MANAGEMENT, LLC More: the full row for GEODE CAPITAL MANAGEMENT, LLC 99,358 $2.72M <0.01% new 13F-HR Timeline Group TD Asset Management Inc More: the full row for TD Asset Management Inc 76,982 $2.11M <0.01% new 13F-HR Timeline Squarepoint Ops LLC in group Squarepoint Ops LLC More: the full row for Squarepoint Ops LLC 48,484 $1.33M <0.01% new 13F-HR Timeline Group TUDOR INVESTMENT CORP ET AL More: the full row for TUDOR INVESTMENT CORP ET AL 44,045 $1.21M <0.01% new 13F-HR Timeline UBS Group AG in group UBS Group AG More: the full row for UBS Group AG 38,698 $1.06M <0.01% new 13F-HR Timeline Group WINTON GROUP Ltd in group WINTON GROUP Ltd More: the full row for WINTON GROUP Ltd 34,900 $955K 0.03% new 13F-HR Timeline Group Balyasny Asset Management L.P. in group Balyasny Asset Management More: the full row for Balyasny Asset Management L.P. 24,264 $664K <0.01% new 13F-HR Timeline Group Hudson Bay Capital Management LP in group Hudson Bay Capital Management… More: the full row for Hudson Bay Capital Management LP 22,690 $621K <0.01% new 13F-HR Timeline Group Brevan Howard Capital Management LP in group Brevan Howard Capital Managem… More: the full row for Brevan Howard Capital Management LP 22,565 $618K 0.01% new 13F-HR Timeline Group Ghisallo Capital Management LLC More: the full row for Ghisallo Capital Management LLC 20,000 $547K 0.01% new 13F-HR Timeline Mitsubishi UFJ Asset Management Co., Lt… in group Mitsubishi UFJ Trust & Bankin… More: the full row for Mitsubishi UFJ Asset Management Co., Ltd. 19,200 $526K <0.01% new 13F-HR Timeline Group Alyeska Investment Group, L.P. in group Alyeska Investment Group, L.P. More: the full row for Alyeska Investment Group, L.P. 10,000 $274K <0.01% new 13F-HR Timeline Group Burkehill Global Management, LP More: the full row for Burkehill Global Management, LP 10,000 $274K 0.01% new 13F-HR Timeline SEVEN GRAND MANAGERS, LLC More: the full row for SEVEN GRAND MANAGERS, LLC 10,000 $274K 0.01% new 13F-HR Timeline ExodusPoint Capital Management, LP More: the full row for ExodusPoint Capital Management, LP 9,691 $265K <0.01% new 13F-HR Timeline Scientech Research LLC More: the full row for Scientech Research LLC 9,564 $262K 0.21% new 13F-HR Timeline TWO SIGMA INVESTMENTS, LP in group TWO SIGMA INVESTMENTS, LP More: the full row for TWO SIGMA INVESTMENTS, LP 8,741 $239K <0.01% new 13F-HR Timeline Group GOLDMAN SACHS GROUP INC in group GOLDMAN SACHS GROUP INC More: the full row for GOLDMAN SACHS GROUP INC 8,253 $226K <0.01% new 13F-HR Timeline Group Persistent Asset Partners Ltd More: the full row for Persistent Asset Partners Ltd 4,130 $113K 0.04% new 13F-HR Timeline Tower Research Capital LLC (TRC) in group Tower Research Capital LLC (T… More: the full row for Tower Research Capital LLC (TRC) 2,070 $56.7K <0.01% new 13F-HR Timeline Group CITIGROUP INC in group CITIGROUP INC More: the full row for CITIGROUP INC 1,869 $51.2K <0.01% new 13F-HR Timeline Group China Universal Asset Management Co., L… More: the full row for China Universal Asset Management Co., Ltd. 1,600 $43.8K <0.01% new 13F-HR Timeline WELLS FARGO & COMPANY/MN in group WELLS FARGO & COMPANY/MN More: the full row for WELLS FARGO & COMPANY/MN 1,152 $31.5K <0.01% new 13F-HR Timeline Group OSAIC HOLDINGS, INC. in group OSAIC HOLDINGS, INC. More: the full row for OSAIC HOLDINGS, INC. 920 $25.2K <0.01% new 13F-HR Timeline Group Parallel Advisors, LLC More: the full row for Parallel Advisors, LLC 550 $15.1K <0.01% new 13F-HR Timeline Rialto Wealth Management, LLC More: the full row for Rialto Wealth Management, LLC 508 $13.9K <0.01% new 13F-HR Timeline Longaeva Partners L.P. More: the full row for Longaeva Partners L.P. 500 $13.7K <0.01% new 13F-HR Timeline Bell Investment Advisors, Inc More: the full row for Bell Investment Advisors, Inc 451 $12.3K <0.01% new 13F-HR Timeline EverSource Wealth Advisors, LLC in group EverSource Wealth Advisors, L… More: the full row for EverSource Wealth Advisors, LLC 261 $7.14K <0.01% new 13F-HR Timeline Group MORGAN STANLEY in group MORGAN STANLEY More: the full row for MORGAN STANLEY 200 $5.47K <0.01% new 13F-HR Timeline Group Atlantic Union Bankshares Corp in group Atlantic Union Bankshares Corp More: the full row for Atlantic Union Bankshares Corp 180 $4.93K <0.01% new 13F-HR Timeline Group JONES FINANCIAL COMPANIES LLLP in group JONES FINANCIAL COMPANIES LLLP More: the full row for JONES FINANCIAL COMPANIES LLLP 103 $2.97K <0.01% new 13F-HR Timeline Group Allworth Financial LP More: the full row for Allworth Financial LP 100 $2.74K <0.01% new 13F-HR Timeline FIFTH THIRD BANCORP in group FIFTH THIRD BANK, NATIONAL AS… More: the full row for FIFTH THIRD BANCORP 60 $1.64K <0.01% new 13F-HR Timeline Group Physician Wealth Advisors, Inc. More: the full row for Physician Wealth Advisors, Inc. 59 $1.61K <0.01% new 13F-HR Timeline North Star Investment Management Corp. More: the full row for North Star Investment Management Corp. 52 $1.42K <0.01% new 13F-HR Timeline Avion Wealth More: the full row for Avion Wealth 69 $1K <0.01% new 13F-HR Timeline Cornerstone Financial Management LLC More: the full row for Cornerstone Financial Management LLC 29 $794 <0.01% new 13F-HR/A Timeline Bogart Wealth, LLC More: the full row for Bogart Wealth, LLC 19 $520 <0.01% new 13F-HR Timeline