Lynx1 Capital Management LP in group Lynx1 Capital Management LP More: the full row for Lynx1 Capital Management LP 13,263,288 $357M 41.19% +2,500,000 13F-HR/A Timeline Group BVF INC/IL in group BVF INC/IL More: the full row for BVF INC/IL 8,650,158 $233M 5.95% 0 13F-HR Timeline Group RA CAPITAL MANAGEMENT, L.P. in group RA CAPITAL MANAGEMENT, L.P. More: the full row for RA CAPITAL MANAGEMENT, L.P. 7,636,813 $205M 1.78% -39,884 13F-HR Timeline Group FMR LLC in group FMR LLC More: the full row for FMR LLC 5,977,045 $161M 0.01% +841,000 13F-HR Timeline Group RTW INVESTMENTS, LP More: the full row for RTW INVESTMENTS, LP 5,933,815 $160M 1.36% 0 13F-HR Timeline Deep Track Capital, LP More: the full row for Deep Track Capital, LP 3,333,334 $89.6M 1.32% new 13F-HR Timeline Avoro Capital Advisors LLC More: the full row for Avoro Capital Advisors LLC 1,800,000 $48.4M 0.43% 0 13F-HR Timeline Foresite Capital Management VI LLC in group Foresite Capital Management V… More: the full row for Foresite Capital Management VI LLC 940,493 $25.3M 3.93% +625,001 13F-HR Timeline Group Jefferies Financial Group Inc. in group Jefferies Financial Group Inc. More: the full row for Jefferies Financial Group Inc. 712,300 $19.1M 0.18% 0 13F-HR Timeline Group BlackRock, Inc. in group BlackRock, Inc. More: the full row for BlackRock, Inc. 480,287 $12.9M <0.01% +24,669 13F-HR Timeline Group UBS Group AG in group UBS Group AG More: the full row for UBS Group AG 477,408 $12.8M <0.01% +64,992 13F-HR Timeline Group MILLENNIUM MANAGEMENT LLC in group MILLENNIUM MANAGEMENT LLC More: the full row for MILLENNIUM MANAGEMENT LLC 323,399 $8.69M 0.01% -614,499 13F-HR Timeline Group BRAIDWELL LP More: the full row for BRAIDWELL LP 207,240 $5.57M 0.21% new 13F-HR Timeline BOOTHBAY FUND MANAGEMENT, LLC More: the full row for BOOTHBAY FUND MANAGEMENT, LLC 202,103 $5.43M 0.1% -80,788 13F-HR Timeline JANE STREET GROUP, LLC in group JANE STREET GROUP, LLC More: the full row for JANE STREET GROUP, LLC 169,951 $4.57M <0.01% new 13F-HR Timeline Group HighVista Strategies LLC More: the full row for HighVista Strategies LLC 158,770 $4.27M 0.97% -54,442 13F-HR Timeline Trexquant Investment LP More: the full row for Trexquant Investment LP 153,767 $4.13M 0.03% +83,959 13F-HR Timeline GOLDMAN SACHS GROUP INC in group GOLDMAN SACHS GROUP INC More: the full row for GOLDMAN SACHS GROUP INC 148,673 $4M <0.01% +103,878 13F-HR Timeline Group XTX Topco Ltd in group XTX Topco Ltd More: the full row for XTX Topco Ltd 86,986 $2.34M 0.03% +34,896 13F-HR Timeline Group CITADEL ADVISORS LLC in group CITADEL ADVISORS LLC More: the full row for CITADEL ADVISORS LLC 85,952 $2.31M <0.01% +20,488 13F-HR Timeline Group AdvisorShares Investments LLC More: the full row for AdvisorShares Investments LLC 71,267 $1.92M 0.23% +4,233 13F-HR Timeline CenterBook Partners LP More: the full row for CenterBook Partners LP 69,436 $1.87M 0.09% -147,138 13F-HR Timeline HRT FINANCIAL LP More: the full row for HRT FINANCIAL LP 65,375 $1.76M <0.01% new 13F-HR Timeline MORGAN STANLEY in group MORGAN STANLEY More: the full row for MORGAN STANLEY 52,218 $1.4M <0.01% +26,388 13F-HR Timeline Group Point72 Asset Management, L.P. in group Point72 Asset Management, L.P. More: the full row for Point72 Asset Management, L.P. 50,882 $1.37M <0.01% new 13F-HR Timeline Group MARSHALL WACE, LLP in group MARSHALL WACE, LLP More: the full row for MARSHALL WACE, LLP 46,697 $1.26M <0.01% -44,411 13F-HR Timeline Group Qube Research & Technologies Ltd More: the full row for Qube Research & Technologies Ltd 43,948 $1.18M <0.01% new 13F-HR Timeline GEODE CAPITAL MANAGEMENT, LLC in group GEODE CAPITAL MANAGEMENT, LLC More: the full row for GEODE CAPITAL MANAGEMENT, LLC 40,483 $1.09M <0.01% 0 13F-HR Timeline Group Axxion S.A. More: the full row for Axxion S.A. 36,170 $972K 0.07% 13F-HR Timeline TUDOR INVESTMENT CORP ET AL More: the full row for TUDOR INVESTMENT CORP ET AL 34,278 $921K <0.01% +15,718 13F-HR Timeline NORTHERN TRUST CORP in group NORTHERN TRUST CORP More: the full row for NORTHERN TRUST CORP 31,844 $856K <0.01% -841 13F-HR Timeline Group D. E. Shaw & Co., Inc. in group D. E. Shaw & Co., Inc. More: the full row for D. E. Shaw & Co., Inc. 25,345 $681K <0.01% new 13F-HR Timeline Group Quadrature Capital Ltd in group Quadrature Capital Ltd More: the full row for Quadrature Capital Ltd 21,117 $568K <0.01% new 13F-HR Timeline Group JPMORGAN CHASE & CO in group JPMORGAN CHASE & CO More: the full row for JPMORGAN CHASE & CO 18,778 $535K <0.01% -75 13F-HR Timeline Group Squarepoint Ops LLC in group Squarepoint Ops LLC More: the full row for Squarepoint Ops LLC 18,430 $495K <0.01% new 13F-HR Timeline Group Virtus Investment Advisers, LLC in group Virtus Investment Advisers, L… More: the full row for Virtus Investment Advisers, LLC 15,492 $416K 0.1% -5,428 13F-HR Timeline Group LETKO, BROSSEAU & ASSOCIATES INC More: the full row for LETKO, BROSSEAU & ASSOCIATES INC 15,425 $415K 0.01% new 13F-HR Timeline China Universal Asset Management Co., L… More: the full row for China Universal Asset Management Co., Ltd. 13,419 $361K 0.02% -88 13F-HR Timeline HighTower Advisors, LLC More: the full row for HighTower Advisors, LLC 12,700 $341K <0.01% -2,900 13F-HR Timeline STATE STREET CORP in group STATE STREET CORP More: the full row for STATE STREET CORP 11,163 $300K <0.01% +114 13F-HR Timeline Group Lion Point Capital, LP More: the full row for Lion Point Capital, LP 10,200 $274K 1.31% 0 13F-HR Timeline Eversept Partners, LP More: the full row for Eversept Partners, LP 8,672 $233K 0.01% new 13F-HR Timeline HSBC HOLDINGS PLC in group HSBC HOLDINGS PLC More: the full row for HSBC HOLDINGS PLC 7,847 $216K <0.01% new 13F-HR Timeline Group BARCLAYS PLC in group BARCLAYS PLC More: the full row for BARCLAYS PLC 5,977 $161K <0.01% +1,583 13F-HR Timeline Group ROYAL BANK OF CANADA in group ROYAL BANK OF CANADA More: the full row for ROYAL BANK OF CANADA 5,877 $158K <0.01% +3,287 13F-HR Timeline Group OSAIC HOLDINGS, INC. in group OSAIC HOLDINGS, INC. More: the full row for OSAIC HOLDINGS, INC. 5,775 $155K <0.01% -150 13F-HR Timeline Group SIMPLEX TRADING, LLC More: the full row for SIMPLEX TRADING, LLC 4,739 $127K <0.01% +4,656 13F-HR Timeline Mirae Asset Global Investments Co., Ltd. in group Mirae Asset Global Investment… More: the full row for Mirae Asset Global Investments Co., Ltd. 3,068 $82.5K <0.01% -167 13F-HR Timeline Group North Star Investment Management Corp. More: the full row for North Star Investment Management Corp. 2,200 $59.1K <0.01% 0 13F-HR Timeline BNP PARIBAS FINANCIAL MARKETS in group BNP PARIBAS FINANCIAL MARKETS More: the full row for BNP PARIBAS FINANCIAL MARKETS 1,697 $45.6K <0.01% +387 13F-HR Timeline Group CITIGROUP INC in group CITIGROUP INC More: the full row for CITIGROUP INC 1,614 $43.4K <0.01% -119 13F-HR Timeline Group GF FUND MANAGEMENT CO. LTD. More: the full row for GF FUND MANAGEMENT CO. LTD. 1,315 $35.3K <0.01% -69 13F-HR Timeline WELLS FARGO & COMPANY/MN in group WELLS FARGO & COMPANY/MN More: the full row for WELLS FARGO & COMPANY/MN 1,250 $33.6K <0.01% 0 13F-HR Timeline Group JONES FINANCIAL COMPANIES LLLP in group JONES FINANCIAL COMPANIES LLLP More: the full row for JONES FINANCIAL COMPANIES LLLP 775 $21.9K <0.01% new 13F-HR Timeline Group HARBOUR INVESTMENTS, INC. More: the full row for HARBOUR INVESTMENTS, INC. 800 $21.5K <0.01% new 13F-HR Timeline Tower Research Capital LLC (TRC) in group Tower Research Capital LLC (T… More: the full row for Tower Research Capital LLC (TRC) 515 $13.8K <0.01% -150 13F-HR Timeline Group SBI Securities Co., Ltd. More: the full row for SBI Securities Co., Ltd. 411 $11K <0.01% +391 13F-HR Timeline Ancora Advisors LLC in group Ancora Advisors LLC More: the full row for Ancora Advisors LLC 284 $7.63K <0.01% 0 13F-HR Timeline Group HOLLENCREST CAPITAL MANAGEMENT More: the full row for HOLLENCREST CAPITAL MANAGEMENT 250 $6.72K <0.01% new 13F-HR Timeline Federation des caisses Desjardins du Qu… More: the full row for Federation des caisses Desjardins du Quebec 205 $5.51K <0.01% new 13F-HR Timeline Farther Finance Advisors, LLC More: the full row for Farther Finance Advisors, LLC 100 $2.69K <0.01% 0 13F-HR Timeline Cornerstone Financial Management LLC More: the full row for Cornerstone Financial Management LLC 32 $860 <0.01% 0 13F-HR/A Timeline Caitong International Asset Management … More: the full row for Caitong International Asset Management Co., Ltd 19 $511 <0.01% new 13F-HR Timeline