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13F-HR filed by RA CAPITAL MANAGEMENT, L.P.

RA CAPITAL MANAGEMENT, L.P. filed this 13F-HR for the quarter ended 2022-03-31, filed 2022-05-16, with 96 holding rows worth $4,583,149,000.

Accession
0001104659-22-061386
Filed
2022-05-16
Accepted by EDGAR
acceptance time not in the bulk data set
Ingested
Source
SEC quarterly data set

Original filing

13F report for Q1 2022

A holdings report, 96 entries on the cover page, a total value of $4,583,149,000 stated on the cover page (in dollars after the unit check, H1), rows summing to $4,583,149,000 with VALUE read as thousands by filing date, 13F file number 028-12884. The quarter's positions are built on this report. The resolved quarter.

The information table after summing rows of one CUSIP and put or call (H4), with the CUSIP and issuer name as filed. Values in dollars after the unit check (method).

Issuer as filedCUSIPClassAmountValueValue read asType
ASCENDIS PHARMA A/S DKK 1.0 AD04351P101SPONSORED ADR7,567,900$888,169,000thousands by filing date
BIOGEN INC COM09062X103Stock727,024$153,111,000thousands by filing date
AEROVATE THERAPEUTICS INC008064107COM8,263,982$151,479,000thousands by filing date
CYTEK BIOSCIENCES INC23285D109COMMON STOCK13,381,054$144,248,000thousands by filing date
ITEOS THERAPEUTICS INC46565G104COM4,417,259$142,147,000thousands by filing date
TRAVERE THERAPEUTICS INC89422G107COM4,922,941$126,864,000thousands by filing date
JANUX THERAPEUTICS INC47103J105COM8,670,644$124,337,000thousands by filing date
VAXCYTE INC COM92243G108Stock4,581,203$110,636,000thousands by filing date
CLIMB BIO INC28658R106COMMON STOCK13,150,849$110,336,000thousands by filing date
IMMUNOGEN INC45253H101COMMON STOCK21,741,458$103,489,000thousands by filing date
DICE THERAPEUTICS INC23345J104COM5,208,911$99,646,000thousands by filing date
GH RESEARCH PLC ORDINARY SHARESG3855L106Stock4,827,330$88,292,000thousands by filing date
FORMA THERAPEUTICS HLDGS INC34633R104SHS9,011,651$83,808,000thousands by filing date
TYRA BIOSCIENCES INC90240B106COMMON STOCK7,236,454$77,430,000thousands by filing date
POINT BIOPHARMA GLOBAL INC730541109COM9,003,018$71,754,000thousands by filing date
CELLDEX THERAPEUTICS INC NEW15117B202COM NEW2,075,000$70,675,000thousands by filing date
BELLUS HEALTH INC NEW07987C204COM10,230,274$70,384,000thousands by filing date
ENANTA PHARMACEUTICALS INC29251M106COM964,212$68,633,000thousands by filing date
VOR BIOPHARMA INC929033108COM11,120,973$67,171,000thousands by filing date
NKARTA INC65487U108COMMON STOCK5,605,129$63,786,000thousands by filing date
MIRATI THERAPEUTICS INC60468T105COM734,343$60,378,000thousands by filing date
Day One Biopharmaceuticals Inc23954D109Common Stock6,060,090$60,116,000thousands by filing date
RHYTHM PHARMACEUTICALS INC76243J105COM4,871,067$56,115,000thousands by filing date
AN2 THERAPEUTICS INC037326105COM3,666,663$55,257,000thousands by filing date
RELMADA THERAPEUTICS INC75955J402COMMON STOCK2,000,000$53,980,000thousands by filing date
MACROGENICS INC556099109COM6,103,594$53,773,000thousands by filing date
NATERA INC COM632307104Stock1,310,289$53,303,000thousands by filing date
Instil Bio, Inc.45783C101Common Stock4,870,793$52,361,000thousands by filing date
NOVAVAX INC670002401COM NEW692,794$51,024,000thousands by filing date
KINNATE BIOPHARMA INC49705R105COM4,264,144$48,014,000thousands by filing date
VERA THERAPEUTICS INC92337R101COMMON STOCK1,966,084$46,183,000thousands by filing date
PARDES BIOSCIENCES INC69945Q105COM6,175,038$44,584,000thousands by filing date
ICOSAVAX INC45114M109COM5,963,565$41,983,000thousands by filing date
TENAYA THERAPEUTICS INC87990A106COM3,551,508$41,837,000thousands by filing date
GERON CORP374163103COM30,126,299$40,972,000thousands by filing date
EYEPOINT INC COM NEW30233G209Stock3,370,506$40,952,000thousands by filing date
AVIDITY BIOSCIENCES INC COM05370A108Stock2,167,391$40,032,000thousands by filing date
ACUMEN PHARMACEUTICALS INC00509G209CMN9,770,773$38,204,000thousands by filing date
RXSIGHT INC78349D107COM3,052,796$37,794,000thousands by filing date
PMV PHARMACEUTICALS INC69353Y103COM1,710,265$35,608,000thousands by filing date
DESIGN THERAPEUTICS INC25056L103COM2,186,636$35,314,000thousands by filing date
ROCKET PHARMACEUTICALS INC77313F106COM2,107,149$33,419,000thousands by filing date
CENTESSA PHARMACEUTICALS PLC152309100SPONSORED ADS3,577,094$32,087,000thousands by filing date
GUARDANT HEALTH INC COM40131M109Stock476,380$31,555,000thousands by filing date
ACLARIS THERAPEUTICS INC COM00461U105Stock1,817,808$31,339,000thousands by filing date
CHEMOCENTRYX INC16383L106COM1,155,964$28,980,000thousands by filing date
KALVISTA PHARMACEUTICALS INC483497103COM1,930,322$28,453,000thousands by filing date
LIANBIO ADR53000N108COM7,655,015$28,400,000thousands by filing date
DYNE THERAPEUTICS INC COM26818M108Stock2,805,045$27,041,000thousands by filing date
VERONA PHARMA PLC925050106SPONSORED ADS5,100,000$25,449,000thousands by filing date
EDGEWISE THERAPEUTICS INC28036F105COM2,613,623$25,352,000thousands by filing date
SATSUMA PHARMACEUTICALS INC80405P107COM5,914,252$22,474,000thousands by filing date
CONNECT BIOPHARMA HLDGS LTD207523101SHS6,991,003$21,113,000thousands by filing date
WEREWOLF THERAPEUTICS INC95075A107CMN4,291,881$18,884,000thousands by filing date
89BIO INC282559103COM4,965,769$18,721,000thousands by filing date
TANGO THERAPEUTICS INC87583X109COM2,250,000$17,055,000thousands by filing date
RELAY THERAPEUTICS INC COM75943R102Stock549,055$16,433,000thousands by filing date
CHINOOK THERAPEUTICS INC16961L106COM1,000,000$16,360,000thousands by filing date
SYNLOGIC INC87166L100COM6,666,666$16,000,000thousands by filing date
WAVE LIFE SCIENCES LTD SHSY95308105Stock7,775,207$15,550,000thousands by filing date
SCPHARMACEUTICALS INC810648105COM2,658,583$15,101,000thousands by filing date
KALA BIO INC COM483119103Stock10,874,613$15,007,000thousands by filing date
SOLID BIOSCIENCES INC COM NEW83422E105Stock12,367,873$14,841,000thousands by filing date
ACHILLES THERAPEUTICS PL-ADR00449L102COM5,014,687$14,743,000thousands by filing date
DA32 LIFE SCNCE TEC ACQSTN C23312M106CLASS A COM1,500,000$14,573,000thousands by filing date
Milestone Pharmaceuticals Inc59935V107COM2,246,503$14,423,000thousands by filing date
Xilio Therapeutics Inc.98422T100COM2,002,217$14,156,000thousands by filing date
GRAPHITE BIO INC38870X104COM2,698,369$13,762,000thousands by filing date
OTONOMY INC68906L105COM5,600,000$13,440,000thousands by filing date
CYTEIR THERAPEUTICS INC23284P103COMMON3,350,506$12,631,000thousands by filing date
BCLS ACQUISITION CORPG0904B105CMN1,250,000$12,338,000thousands by filing date
CENTURY THERAPEUTICS INC15673T100COM914,094$11,508,000thousands by filing date
MORPHIC HLDG INC61775R105COM278,874$11,197,000thousands by filing date
AKOUOS INC00973J101COM2,281,249$10,836,000thousands by filing date
CONCERT PHARMACEUTICALS INC206022105COM3,033,603$10,223,000thousands by filing date
FRAZIER LIFESCIENCES ACQU CORP UNIT EXP 120925G3710A121Stock1,000,000$9,990,000thousands by filing date
IO BIOTECH INC449778109COM1,857,755$9,846,000thousands by filing date
ALLOVIR INC019818103COM1,440,525$9,724,000thousands by filing date
ARYA SCIENCES ACQUISITN CORPG31658100CLASS A ORD SHS1,000,000$9,710,000thousands by filing date
PYXIS ONCOLOGY INC COMMON STOCK747324101Stock2,282,173$9,220,000thousands by filing date
ASTRIA THERAPEUTICS INC COM04635X102Stock1,262,193$8,469,000thousands by filing date
5 01 ACQUISITION CORP33836P105CMN750,000$7,388,000thousands by filing date
BLACK DIAMOND THERAPEUTICS I09203E105COM2,589,904$7,174,000thousands by filing date
VERVE THERAPEUTICS INC92539P101COM310,284$7,081,000thousands by filing date
ORCHARD THERAPEUTICS PLC68570P101ADR9,694,789$6,903,000thousands by filing date
ENTERA BIO LTDM40527109SHS2,353,000$6,753,000thousands by filing date
HEALTH SCIENCES ACQ CORP 2G4411D109ORD SHS625,000$6,194,000thousands by filing date
LARIMAR THERAPEUTICS INC517125100COM1,281,860$5,192,000thousands by filing date
CUE HEALTH INC229790100COM750,000$4,838,000thousands by filing date
PHASEBIO PHARMACEUTICALS INC717224109COM2,850,000$3,762,000thousands by filing date
CULLINAN THERAPEUTICS INC230031106COM350,000$3,665,000thousands by filing date
Tscan Therapeutics Inc89854M101COM1,021,764$2,861,000thousands by filing date
BIOMEA FUSION INC09077A106CMN500,000$2,230,000thousands by filing date
OLEMA PHARMACEUTICALS INC68062P106COM504,505$2,149,000thousands by filing date
CVRX INC126638105COMMON STOCK275,000$1,647,000thousands by filing date
COMPASS THERAPEUTICS INC20454B104COM532,958$730,000thousands by filing date

Amendment chain

FilingRoleFiledAcceptedIngested
13F-HR 0001104659-22-061386this filing2022-05-16acceptance time not in the bulk data set