Jupiter Topco LLC in group Janus Henderson More: the full row for Jupiter Topco LLC 1,349,107 $94.8M 0.04% 13F-HR Timeline Group Cormorant Asset Management, LP More: the full row for Cormorant Asset Management, LP 900,000 $63.2M 3.24% -159,331 13F-HR Timeline BlackRock, Inc. in group BlackRock, Inc. More: the full row for BlackRock, Inc. 686,184 $48.2M <0.01% +64,251 13F-HR Timeline Group Vivo Capital, LLC More: the full row for Vivo Capital, LLC 557,172 $39.1M 3.57% 0 13F-HR Timeline Vestal Point Capital, LP More: the full row for Vestal Point Capital, LP 545,000 $38.3M 0.89% +52,681 13F-HR Timeline BRAIDWELL LP More: the full row for BRAIDWELL LP 483,822 $34M 1.26% -55,886 13F-HR Timeline Driehaus Capital Management LLC More: the full row for Driehaus Capital Management LLC 433,377 $30.4M 0.18% +862 13F-HR Timeline Balyasny Asset Management L.P. in group Balyasny Asset Management More: the full row for Balyasny Asset Management L.P. 345,053 $24.2M 0.04% +47,895 13F-HR Timeline Group ADAGE CAPITAL PARTNERS GP, L.L.C. in group ADAGE CAPITAL PARTNERS GP, L.… More: the full row for ADAGE CAPITAL PARTNERS GP, L.L.C. 335,000 $23.5M 0.03% -160,743 13F-HR Timeline Group Point72 Asset Management, L.P. in group Point72 Asset Management, L.P. More: the full row for Point72 Asset Management, L.P. 327,416 $23M 0.04% new 13F-HR Timeline Group DEERFIELD MANAGEMENT COMPANY, L.P. in group DEERFIELD MANAGEMENT COMPANY,… More: the full row for DEERFIELD MANAGEMENT COMPANY, L.P. 283,000 $19.9M 0.21% 0 13F-HR Timeline Group RA CAPITAL MANAGEMENT, L.P. in group RA CAPITAL MANAGEMENT, L.P. More: the full row for RA CAPITAL MANAGEMENT, L.P. 265,000 $18.6M 0.16% 0 13F-HR Timeline Group Parkman Healthcare Partners LLC More: the full row for Parkman Healthcare Partners LLC 205,053 $14.4M 1.48% +164,955 13F-HR Timeline MPM BIOIMPACT LLC More: the full row for MPM BIOIMPACT LLC 202,114 $14.2M 0.87% -10,061 13F-HR Timeline WELLINGTON MANAGEMENT GROUP LLP in group WELLINGTON MANAGEMENT GROUP L… More: the full row for WELLINGTON MANAGEMENT GROUP LLP 171,315 $12M <0.01% +34,638 13F-HR Timeline Group GOLDMAN SACHS GROUP INC in group GOLDMAN SACHS GROUP INC More: the full row for GOLDMAN SACHS GROUP INC 133,689 $9.38M <0.01% +59,320 13F-HR Timeline Group EVENTIDE ASSET MANAGEMENT, LLC More: the full row for EVENTIDE ASSET MANAGEMENT, LLC 130,013 $9.13M 0.12% 0 13F-HR Timeline STATE STREET CORP in group STATE STREET CORP More: the full row for STATE STREET CORP 122,178 $8.58M <0.01% +13,939 13F-HR Timeline Group SEVEN GRAND MANAGERS, LLC More: the full row for SEVEN GRAND MANAGERS, LLC 120,000 $8.42M 0.34% 0 13F-HR Timeline GREAT POINT PARTNERS LLC More: the full row for GREAT POINT PARTNERS LLC 109,603 $7.69M 1.81% -110,397 13F-HR Timeline GEODE CAPITAL MANAGEMENT, LLC in group GEODE CAPITAL MANAGEMENT, LLC More: the full row for GEODE CAPITAL MANAGEMENT, LLC 104,146 $7.31M <0.01% +15,430 13F-HR Timeline Group ORBIMED ADVISORS LLC in group ORBIMED ADVISORS LLC More: the full row for ORBIMED ADVISORS LLC 93,000 $6.53M 0.12% +53,000 13F-HR Timeline Group ACUTA CAPITAL PARTNERS, LLC More: the full row for ACUTA CAPITAL PARTNERS, LLC 92,745 $6.51M 4.54% -19,251 13F-HR Timeline VANGUARD GROUP INC group of 3 filers holding More: the full row for VANGUARD GROUP INC 90,931 $6.38M +21,329 Timeline Ikarian Capital, LLC More: the full row for Ikarian Capital, LLC 88,951 $6.24M 1.02% -77,696 13F-HR Timeline Sio Capital Management, LLC More: the full row for Sio Capital Management, LLC 73,952 $5.19M 0.89% -12,131 13F-HR Timeline Trexquant Investment LP More: the full row for Trexquant Investment LP 70,615 $4.96M 0.03% +63,164 13F-HR Timeline B Group, Inc. More: the full row for B Group, Inc. 67,500 $4.74M 2.69% 0 13F-HR Timeline MILLENNIUM MANAGEMENT LLC in group MILLENNIUM MANAGEMENT LLC More: the full row for MILLENNIUM MANAGEMENT LLC 66,740 $4.69M <0.01% +13,908 13F-HR Timeline Group CITADEL ADVISORS LLC in group CITADEL ADVISORS LLC More: the full row for CITADEL ADVISORS LLC 66,533 $4.67M <0.01% new 13F-HR Timeline Group Schonfeld Strategic Advisors LLC More: the full row for Schonfeld Strategic Advisors LLC 66,277 $4.65M 0.02% +53,033 13F-HR Timeline Walleye Capital LLC in group Walleye Capital LLC More: the full row for Walleye Capital LLC 66,106 $4.64M 0.02% +12,400 13F-HR Timeline Group Woodline Partners LP More: the full row for Woodline Partners LP 45,668 $3.21M 0.01% 0 13F-HR Timeline NORTHERN TRUST CORP in group NORTHERN TRUST CORP More: the full row for NORTHERN TRUST CORP 42,466 $2.98M <0.01% +5,088 13F-HR Timeline Group Artia Global Partners LP More: the full row for Artia Global Partners LP 38,407 $2.7M 0.51% 0 13F-HR Timeline AMERIPRISE FINANCIAL INC in group AMERIPRISE FINANCIAL INC More: the full row for AMERIPRISE FINANCIAL INC 37,902 $2.66M <0.01% -12,125 13F-HR Timeline Group LOS ANGELES CAPITAL MANAGEMENT LLC More: the full row for LOS ANGELES CAPITAL MANAGEMENT LLC 35,747 $2.51M 0.01% new 13F-HR Timeline KVP Capital Advisors, LP More: the full row for KVP Capital Advisors, LP 31,813 $2.23M 1.64% 0 13F-HR Timeline SUPERSTRING CAPITAL MANAGEMENT LP More: the full row for SUPERSTRING CAPITAL MANAGEMENT LP 30,456 $2.14M 1.35% +17,145 13F-HR Timeline ADAR1 Capital Management, LLC in group ADAR1 Capital Management, LLC More: the full row for ADAR1 Capital Management, LLC 30,300 $2.13M 0.1% -3,600 13F-HR Timeline Group BOOTHBAY FUND MANAGEMENT, LLC More: the full row for BOOTHBAY FUND MANAGEMENT, LLC 27,870 $1.96M 0.04% -23,420 13F-HR Timeline BANK OF AMERICA CORP /DE/ in group BANK OF AMERICA CORP /DE/ More: the full row for BANK OF AMERICA CORP /DE/ 26,966 $1.89M <0.01% +7,544 13F-HR Timeline Group AdvisorShares Investments LLC More: the full row for AdvisorShares Investments LLC 24,274 $1.7M 0.21% +11,661 13F-HR Timeline Aquatic Capital Management LLC More: the full row for Aquatic Capital Management LLC 20,831 $1.46M 0.05% +18,786 13F-HR Timeline PLATINUM INVESTMENT MANAGEMENT LTD More: the full row for PLATINUM INVESTMENT MANAGEMENT LTD 19,127 $1.34M 0.33% 0 13F-HR Timeline MORGAN STANLEY in group MORGAN STANLEY More: the full row for MORGAN STANLEY 18,599 $1.31M <0.01% -114,165 13F-HR Timeline Group CHARLES SCHWAB INVESTMENT MANAGEMENT INC in group Charles Schwab Trust Co More: the full row for CHARLES SCHWAB INVESTMENT MANAGEMENT INC 18,032 $1.27M <0.01% +2,714 13F-HR Timeline Group Nuveen, LLC in group TIAA More: the full row for Nuveen, LLC 16,889 $1.19M <0.01% +8,560 13F-HR Timeline Group UBS Group AG in group UBS Group AG More: the full row for UBS Group AG 15,536 $1.09M <0.01% +2,256 13F-HR Timeline Group Bank of New York Mellon Corp in group Bank of New York Mellon Corp More: the full row for Bank of New York Mellon Corp 14,902 $1.05M <0.01% +1,649 13F-HR Timeline Group Exome Asset Management LLC More: the full row for Exome Asset Management LLC 10,110 $710K 0.44% new 13F-HR Timeline TWO SIGMA INVESTMENTS, LP in group TWO SIGMA INVESTMENTS, LP More: the full row for TWO SIGMA INVESTMENTS, LP 9,606 $674K <0.01% new 13F-HR Timeline Group RHUMBLINE ADVISERS More: the full row for RHUMBLINE ADVISERS 8,733 $613K <0.01% +971 13F-HR Timeline TUDOR INVESTMENT CORP ET AL More: the full row for TUDOR INVESTMENT CORP ET AL 8,291 $582K <0.01% new 13F-HR Timeline FRANKLIN RESOURCES INC in group Franklin Resources More: the full row for FRANKLIN RESOURCES INC 8,020 $563K <0.01% new 13F-HR Timeline Group FMR LLC in group FMR LLC More: the full row for FMR LLC 7,851 $551K <0.01% +7,032 13F-HR Timeline Group DEUTSCHE BANK AG\ in group DEUTSCHE BANK AG\ More: the full row for DEUTSCHE BANK AG\ 7,808 $548K <0.01% +1,550 13F-HR Timeline Group ARROWSTREET CAPITAL, LIMITED PARTNERSHIP in group ARROWSTREET CAPITAL, LIMITED … More: the full row for ARROWSTREET CAPITAL, LIMITED PARTNERSHIP 7,199 $505K <0.01% new 13F-HR Timeline Group LPL Financial LLC More: the full row for LPL Financial LLC 6,895 $484K <0.01% +400 13F-HR Timeline WELLS FARGO & COMPANY/MN in group WELLS FARGO & COMPANY/MN More: the full row for WELLS FARGO & COMPANY/MN 6,761 $475K <0.01% +4,229 13F-HR Timeline Group JANE STREET GROUP, LLC in group JANE STREET GROUP, LLC More: the full row for JANE STREET GROUP, LLC 6,400 $449K <0.01% 0 13F-HR Timeline Group Seven Fleet Capital Management LP More: the full row for Seven Fleet Capital Management LP 6,395 $449K 0.07% 0 13F-HR Timeline PRICE T ROWE ASSOCIATES INC /MD/ More: the full row for PRICE T ROWE ASSOCIATES INC /MD/ 6,167 $433K <0.01% +1,220 13F-HR Timeline STATE BOARD OF ADMINISTRATION OF FLORID… More: the full row for STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM 6,091 $428K <0.01% +2,310 13F-HR Timeline ALLIANCEBERNSTEIN L.P. More: the full row for ALLIANCEBERNSTEIN L.P. 5,680 $414K <0.01% new 13F-HR Timeline Engineers Gate Manager LP More: the full row for Engineers Gate Manager LP 5,412 $380K <0.01% new 13F-HR Timeline DNB Asset Management AS in group DNB Asset Management AS More: the full row for DNB Asset Management AS 4,822 $339K <0.01% +381 13F-HR Timeline Group JPMORGAN CHASE & CO in group JPMORGAN CHASE & CO More: the full row for JPMORGAN CHASE & CO 4,778 $331K <0.01% +901 13F-HR Timeline Group MetLife Investment Management, LLC in group MetLife Investment Management… More: the full row for MetLife Investment Management, LLC 4,511 $317K <0.01% +600 13F-HR Timeline Group Invesco Ltd. in group Invesco Ltd. More: the full row for Invesco Ltd. 4,016 $282K <0.01% -2,280 13F-HR Timeline Group CITIGROUP INC in group CITIGROUP INC More: the full row for CITIGROUP INC 3,612 $260K <0.01% +3,315 13F-HR Timeline Group MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. in group Mirae Asset Global Investment… More: the full row for MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 3,412 $240K <0.01% +152 13F-HR Timeline Group STRS OHIO More: the full row for STRS OHIO 3,300 $232K <0.01% +600 13F-HR Timeline BARCLAYS PLC in group BARCLAYS PLC More: the full row for BARCLAYS PLC 3,256 $229K <0.01% +179 13F-HR Timeline Group NEW YORK STATE COMMON RETIREMENT FUND More: the full row for NEW YORK STATE COMMON RETIREMENT FUND 2,600 $183K <0.01% 0 13F-HR Timeline Russell Investments Group, Ltd. in group Russell Investments Group, Lt… More: the full row for Russell Investments Group, Ltd. 2,553 $179K <0.01% +1,671 13F-HR Timeline Group Police & Firemen's Retirement System of… More: the full row for Police & Firemen's Retirement System of New Jersey 2,036 $143K <0.01% 0 13F-HR Timeline BNP PARIBAS FINANCIAL MARKETS in group BNP PARIBAS FINANCIAL MARKETS More: the full row for BNP PARIBAS FINANCIAL MARKETS 1,234 $86.6K <0.01% -337 13F-HR Timeline Group Caitong International Asset Management … More: the full row for Caitong International Asset Management Co., Ltd 1,201 $84.3K 0.01% new 13F-HR Timeline ROYAL BANK OF CANADA in group ROYAL BANK OF CANADA More: the full row for ROYAL BANK OF CANADA 1,133 $80K <0.01% +727 13F-HR Timeline Group Tower Research Capital LLC (TRC) in group Tower Research Capital LLC (T… More: the full row for Tower Research Capital LLC (TRC) 1,011 $71K <0.01% +414 13F-HR Timeline Group Legal & General Group Plc in group Legal & General Group Plc More: the full row for Legal & General Group Plc 718 $50.5K <0.01% +102 13F-HR Timeline Group Ameritas Investment Partners, Inc. in group Ameritas Investment Partners,… More: the full row for Ameritas Investment Partners, Inc. 672 $47.2K <0.01% +202 13F-HR Timeline Group China Universal Asset Management Co., L… More: the full row for China Universal Asset Management Co., Ltd. 600 $42.1K <0.01% +100 13F-HR Timeline State of Wyoming More: the full row for State of Wyoming 479 $33.6K <0.01% new 13F-HR Timeline Pinnacle Wealth Planning Services, Inc. More: the full row for Pinnacle Wealth Planning Services, Inc. 138 $9.69K <0.01% new 13F-HR Timeline CALIFORNIA STATE TEACHERS RETIREMENT SY… More: the full row for CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 98 $6.88K <0.01% -282 13F-HR/A Timeline OSAIC HOLDINGS, INC. in group OSAIC HOLDINGS, INC. More: the full row for OSAIC HOLDINGS, INC. 80 $5.62K <0.01% new 13F-HR Timeline Group Allworth Financial LP More: the full row for Allworth Financial LP 48 $3.37K <0.01% +45 13F-HR Timeline Quarry LP More: the full row for Quarry LP 27 $1.9K <0.01% new 13F-HR Timeline Sterling Capital Management LLC More: the full row for Sterling Capital Management LLC 26 $1.82K <0.01% -19 13F-HR Timeline GAMMA Investing LLC More: the full row for GAMMA Investing LLC 20 $1.4K <0.01% -13 13F-HR Timeline Integrated Wealth Concepts LLC More: the full row for Integrated Wealth Concepts LLC 20 $1.4K <0.01% new 13F-HR Timeline TD Waterhouse Canada Inc. More: the full row for TD Waterhouse Canada Inc. 20 $1.33K <0.01% new 13F-HR Timeline Arax Advisory Partners More: the full row for Arax Advisory Partners 11 $772 <0.01% new 13F-HR Timeline Bell Investment Advisors, Inc More: the full row for Bell Investment Advisors, Inc 6 $422 <0.01% 0 13F-HR Timeline SBI Securities Co., Ltd. More: the full row for SBI Securities Co., Ltd. 5 $351 <0.01% 0 13F-HR Timeline SJS Investment Consulting Inc. More: the full row for SJS Investment Consulting Inc. 5 $351 <0.01% new 13F-HR Timeline