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Disclosery

SION SIONNA THERAPEUTICS INC

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COMMON STOCK (common), issuer CIK 2036042

140 managers (147 13F filers) reported a position in SION shares at 2026-06-30, 48,084,318 shares in all. 34 filers opened a position and 8 filers sold out during the quarter.

Managers
140
13F filers
147
New
34
Added
58
Reduced
39
Sold out
8
Shares held by filers
48,084,318

Shares held by filers adds up every 13F filer's report, so a share reported by a parent and by its subsidiary counts twice (H9). Managers counts each filer group once.

13D and 13G filers

No 13D or 13G on this security in the data. Structured 13D/G data starts 2024-12-18.

Insider trades

No Form 4 transaction on this security in the data.

13F holders, Q2 2026

Filers in the available 13F reports with a share position at 2026-06-30, filer groups collapsed to one row (method), largest first. Options and principal amounts are left out. A group row states no % of portfolio, since each member reports its own portfolio: the members' percents are listed under it. A value about 1,000 times or 1/1,000 of the price other filers imply is shown as filed but neither ranks the row nor enters a sum.

HolderSharesValue% of portfolioChangeSource
RA CAPITAL MANAGEMENT, L.P.in group RA CAPITAL MANAGEMENT, L.P.9,905,045$436M3.79%013F-HRTimelineGroup
TPG GP A, LLCin group TPG GP A, LLC6,494,962$286M5.71%013F-HRTimelineGroup
VIKING GLOBAL INVESTORS LPin group VIKING GLOBAL INVESTORS LP3,195,181$141M0.4%013F-HRTimelineGroup
Atlas Venture Life Science Advisors, LLC2,995,602$132M14.95%013F-HRTimeline
ORBIMED ADVISORS LLCin group ORBIMED ADVISORS LLC2,555,877$112M2.13%-974,82513F-HRTimelineGroup
ENAVATE SCIENCES GP, LLC2,478,030$109M31.56%013F-HRTimeline
ADAGE CAPITAL PARTNERS GP, L.L.C.in group ADAGE CAPITAL PARTNERS GP, L.…1,600,000$70.4M0.1%+1,450,00013F-HRTimelineGroup
VANGUARD GROUP INCgroup of 6 filers holding1,497,269$65.9M+202,325Timeline
BlackRock, Inc.in group BlackRock, Inc.1,474,769$64.9M<0.01%+178,90213F-HRTimelineGroup
JPMORGAN CHASE & COin group JPMORGAN CHASE & CO1,490,508$64.1M<0.01%+25,49413F-HRTimelineGroup
JENNISON ASSOCIATES LLC1,172,133$51.6M0.03%-279,08713F-HRTimeline
CITADEL ADVISORS LLCin group CITADEL ADVISORS LLC1,147,636$50.5M0.03%-19,29513F-HRTimelineGroup
STATE STREET CORPin group STATE STREET CORP1,021,534$44.9M<0.01%+265,30713F-HRTimelineGroup
PERCEPTIVE ADVISORS LLCin group PERCEPTIVE ADVISORS LLC905,000$39.8M0.62%+246,56113F-HRTimelineGroup
DEERFIELD MANAGEMENT COMPANY, L.P.in group DEERFIELD MANAGEMENT COMPANY,…680,916$30M0.31%-289,67413F-HRTimelineGroup
Siren, L.L.C.in group Siren, L.L.C.610,515$26.9M0.55%+310,51513F-HRTimelineGroup
PRICE T ROWE ASSOCIATES INC /MD/478,016$21M<0.01%-278,36013F-HRTimeline
EVENTIDE ASSET MANAGEMENT, LLC474,981$20.9M0.28%-170,54913F-HRTimeline
GEODE CAPITAL MANAGEMENT, LLCin group GEODE CAPITAL MANAGEMENT, LLC457,145$20.1M<0.01%+67,27313F-HRTimelineGroup
BAKER BROS. ADVISORS LPin group BAKER BROS. ADVISORS LP400,000$17.6M0.09%013F-HRTimelineGroup
Casdin Capital, LLC400,000$17.6M0.88%new13F-HRTimeline
GOLDMAN SACHS GROUP INCin group GOLDMAN SACHS GROUP INC388,810$17.1M<0.01%+125,63613F-HRTimelineGroup
Driehaus Capital Management LLC385,447$17M0.1%+308,81413F-HRTimeline
FRANKLIN RESOURCES INCin group Franklin Resources290,113$12.8M<0.01%+114,63013F-HRTimelineGroup
Aberdeen Group plcin group Aberdeen Group plc284,138$12.5M0.02%-280,03713F-HRTimelineGroup
FMR LLCin group FMR LLC278,292$12.2M<0.01%+196,89713F-HRTimelineGroup
MILLENNIUM MANAGEMENT LLCin group MILLENNIUM MANAGEMENT LLC276,733$12.2M0.01%+136,09213F-HRTimelineGroup
Candriam S.C.A.233,208$10.2M0.05%-3,60513F-HRTimeline
Kalehua Capital Management LLC197,072$8.67M4.98%013F-HR/ATimeline
Longaeva Partners L.P.196,352$8.64M0.25%+183,65913F-HRTimeline
Artisan Partners Limited Partnership189,498$8.34M0.01%new13F-HRTimeline
Ensign Peak Advisors, Inc184,532$8.12M0.01%-71,10413F-HRTimeline
Soleus Capital Management, L.P.177,687$7.82M0.27%-115,81313F-HRTimeline
NORTHERN TRUST CORPin group NORTHERN TRUST CORP154,476$6.8M<0.01%+37,70013F-HRTimelineGroup
MORGAN STANLEYin group MORGAN STANLEY151,047$6.64M<0.01%+18,02413F-HRTimelineGroup
Sofinnova Investments, Inc.144,432$6.35M0.34%new13F-HRTimeline
Qube Research & Technologies Ltd140,309$6.17M0.01%+98,06713F-HRTimeline
Alyeska Investment Group, L.P.in group Alyeska Investment Group, L.P.136,222$5.99M0.02%013F-HRTimelineGroup
GordonMD Global Investments LPin group GordonMD Global Investments LP136,000$5.98M2.89%013F-HRTimelineGroup
CHARLES SCHWAB INVESTMENT MANAGEMENT INCin group Charles Schwab Trust Co129,753$5.71M<0.01%+9,50013F-HRTimelineGroup
Sio Capital Management, LLC127,808$5.62M0.96%-166,53213F-HRTimeline
UBS Group AGgroup of 2 filers holding126,828$5.58M-20,929Timeline
Artia Global Partners LP119,741$5.27M1%013F-HRTimeline
First Turn Management, LLC110,493$4.86M0.52%new13F-HRTimeline
CITIGROUP INCin group CITIGROUP INC110,163$4.85M<0.01%+92,10513F-HRTimelineGroup
D. E. Shaw & Co., Inc.in group D. E. Shaw & Co., Inc.101,644$4.47M<0.01%new13F-HRTimelineGroup
Rock Springs Capital Management LP99,429$4.37M0.21%013F-HRTimeline
Walleye Capital LLCin group Walleye Capital LLC97,347$4.28M0.02%+82,25013F-HRTimelineGroup
Rhenman & Partners Asset Management AB97,100$4.27M0.4%+9,60013F-HRTimeline
BANK OF AMERICA CORP /DE/in group BANK OF AMERICA CORP /DE/88,908$3.91M<0.01%+38,03813F-HRTimelineGroup
AMERIPRISE FINANCIAL INCin group AMERIPRISE FINANCIAL INC82,232$3.62M<0.01%+25813F-HRTimelineGroup
Integral Health Asset Management, LLC75,000$3.3M0.14%+25,00013F-HRTimeline
SUPERSTRING CAPITAL MANAGEMENT LP63,156$2.78M1.75%-77,86813F-HRTimeline
STEMPOINT CAPITAL LP59,426$2.61M0.45%+22,88613F-HRTimeline
DEUTSCHE BANK AG\in group DEUTSCHE BANK AG\53,353$2.35M<0.01%+40,10413F-HRTimelineGroup
SEVEN GRAND MANAGERS, LLC50,000$2.2M0.09%013F-HRTimeline
Point72 Asset Management, L.P.in group Point72 Asset Management, L.P.49,328$2.17M<0.01%-87,22113F-HRTimelineGroup
TD Asset Management Inc47,396$2.08M<0.01%-35,60013F-HRTimeline
ALPS ADVISORS INC45,525$2M0.01%+8,89713F-HRTimeline
SILVERARC CAPITAL MANAGEMENT, LLCin group SILVERARC CAPITAL MANAGEMENT,…42,478$1.87M0.21%+3,06113F-HRTimelineGroup
Russell Investments Group, Ltd.in group Russell Investments Group, Lt…42,258$1.86M<0.01%-6,16113F-HRTimelineGroup
Bank of New York Mellon Corpin group Bank of New York Mellon Corp41,586$1.83M<0.01%+7,80813F-HRTimelineGroup
Nuveen, LLCin group TIAA41,259$1.81M<0.01%+17,52513F-HRTimelineGroup
XTX Topco Ltdin group XTX Topco Ltd38,096$1.68M0.02%+14,54513F-HRTimelineGroup
WELLINGTON MANAGEMENT GROUP LLPin group WELLINGTON MANAGEMENT GROUP L…37,365$1.64M<0.01%-8,71413F-HRTimelineGroup
MUTUAL OF AMERICA CAPITAL MANAGEMENT LLCin group MUTUAL OF AMERICA CAPITAL MAN…35,968$1.58M0.02%new13F-HRTimelineGroup
MANUFACTURERS LIFE INSURANCE COMPANY, T…in group MANUFACTURERS LIFE INSURANCE …35,420$1.56M<0.01%-29,03813F-HRTimelineGroup
BNP PARIBAS FINANCIAL MARKETSin group BNP PARIBAS FINANCIAL MARKETS31,803$1.4M<0.01%-8,76713F-HRTimelineGroup
Ishara Investments LP123,000$1.35M0.99%+73,80013F-HRTimeline
Swiss National Bank27,000$1.19M<0.01%new13F-HRTimeline
Quadrature Capital Ltdin group Quadrature Capital Ltd26,023$1.14M0.01%new13F-HRTimelineGroup
Trexquant Investment LP23,810$1.05M0.01%new13F-HRTimeline
NEW YORK STATE COMMON RETIREMENT FUND23,586$1.04M<0.01%+18,28613F-HRTimeline
ALLIANCEBERNSTEIN L.P.25,450$1.02M<0.01%+9,04013F-HRTimeline
TUDOR INVESTMENT CORP ET AL22,575$993K<0.01%new13F-HRTimeline
RHUMBLINE ADVISERS22,309$981K<0.01%+4,00113F-HRTimeline
Maven Securities LTDin group Maven Securities LTD20,000$880K0.06%-5,00013F-HRTimelineGroup
LOS ANGELES CAPITAL MANAGEMENT LLC18,645$820K<0.01%+14,52913F-HRTimeline
SUSQUEHANNA INTERNATIONAL GROUP, LLPgroup of 2 filers holding18,034$793K+10,724Timeline
Rafferty Asset Management, LLC18,004$792K<0.01%-4,13313F-HRTimeline
Shay Capital LLC18,000$792K0.09%new13F-HRTimeline
WELLS FARGO & COMPANY/MNin group WELLS FARGO & COMPANY/MN16,821$740K<0.01%+10,92713F-HRTimelineGroup
Engineers Gate Manager LP15,603$686K0.01%new13F-HRTimeline
CALIFORNIA STATE TEACHERS RETIREMENT SY…14,852$653K<0.01%+13,98413F-HR/ATimeline
KENNEDY CAPITAL MANAGEMENT LLC12,621$555K0.01%+33713F-HRTimeline
MARSHALL WACE, LLPin group MARSHALL WACE, LLP12,599$554K<0.01%new13F-HRTimelineGroup
Mirae Asset Global Investments Co., Ltd.group of 2 filers holding12,601$552K+1,088Timeline
Invesco Ltd.in group Invesco Ltd.12,418$546K<0.01%+1,63113F-HRTimelineGroup
MetLife Investment Management, LLCin group MetLife Investment Management…10,972$483K<0.01%+2,40713F-HRTimelineGroup
Jump Financial, LLCin group Jump Financial, LLC10,473$461K<0.01%new13F-HRTimelineGroup
PROFUND ADVISORS LLC9,140$402K0.01%-79913F-HRTimeline
Virtus Investment Advisers, LLCin group Virtus Investment Advisers, L…9,109$401K0.09%+2,73513F-HRTimelineGroup
Legal & General Group Plcin group Legal & General Group Plc9,044$398K<0.01%+7,61213F-HRTimelineGroup
China Universal Asset Management Co., L…7,186$316K0.02%-73413F-HRTimeline
Quarry LP6,750$297K0.05%+44613F-HRTimeline
BARCLAYS PLCin group BARCLAYS PLC6,495$286K<0.01%-11,89013F-HRTimelineGroup
VARCOV Co.6,418$282K0.11%-15313F-HRTimeline
Jupiter Topco LLCin group Janus Henderson6,400$281K<0.01%13F-HRTimelineGroup
Police & Firemen's Retirement System of…5,438$239K<0.01%+1,20613F-HRTimeline
Squarepoint Ops LLCin group Squarepoint Ops LLC5,415$238K<0.01%-9,80213F-HRTimelineGroup
INTECH INVESTMENT MANAGEMENT LLC5,218$230K<0.01%-27113F-HRTimeline
STATE BOARD OF ADMINISTRATION OF FLORID…5,215$229K<0.01%new13F-HRTimeline
SEI INVESTMENTS COin group SEI INVESTMENTS CO5,158$227K<0.01%new13F-HRTimelineGroup
AlphaCentric Advisors LLC4,863$214K0.18%+4513F-HRTimeline
Jain Global LLC4,780$210K<0.01%new13F-HRTimeline
AXQ CAPITAL, LP4,597$202K0.02%new13F-HRTimeline
STRS OHIO3,500$154K<0.01%+60013F-HRTimeline
KLP KAPITALFORVALTNING AS3,100$136K<0.01%new13F-HRTimeline
Quantbot Technologies LP1,820$80.1K<0.01%+1,64213F-HRTimeline
Ameritas Investment Partners, Inc.in group Ameritas Investment Partners,…1,673$73.6K<0.01%+37113F-HRTimelineGroup
Tower Research Capital LLC (TRC)in group Tower Research Capital LLC (T…1,279$56.3K<0.01%-1,07313F-HRTimelineGroup
Mitsubishi UFJ Asset Management Co., Lt…in group Mitsubishi UFJ Trust & Bankin…1,000$44K<0.01%new13F-HRTimelineGroup
GF FUND MANAGEMENT CO. LTD.946$41.6K<0.01%-5713F-HRTimeline
State of Wyoming804$35.4K<0.01%new13F-HRTimeline
Zurcher Kantonalbank (Zurich Cantonalba…709$31.2K<0.01%+33813F-HRTimeline
ROYAL BANK OF CANADAin group ROYAL BANK OF CANADA568$25K<0.01%+53813F-HRTimelineGroup
NISA INVESTMENT ADVISORS, LLC385$16.9K<0.01%new13F-HRTimeline
Pacer Advisors, Inc.301$13K<0.01%new13F-HRTimeline
GAMMA Investing LLC244$10.7K<0.01%+613F-HRTimeline
Federation des caisses Desjardins du Qu…210$9.24K<0.01%new13F-HRTimeline
Farther Finance Advisors, LLC196$8.62K<0.01%013F-HRTimeline
Rockefeller Capital Management L.P.in group Rockefeller Capital Managemen…114$5.01K<0.01%-12713F-HRTimelineGroup
Hurley Capital, LLC113$4.97K<0.01%new13F-HRTimeline
US BANCORP \DE\in group US BANCORP \DE\104$4.58K<0.01%+5313F-HRTimelineGroup
Sterling Capital Management LLC65$2.86K<0.01%-4013F-HRTimeline
Arax Advisory Partners41$1.8K<0.01%new13F-HRTimeline
Bare Financial Services, Inc37$1.63K<0.01%new13F-HRTimeline
Caitong International Asset Management …31$1.36K<0.01%-513F-HRTimeline
Hughes Financial Services, LLC25$1.1K<0.01%-113F-HRTimeline
Covestor Ltd12$1K<0.01%+913F-HRTimeline
EverSource Wealth Advisors, LLCin group EverSource Wealth Advisors, L…20$880<0.01%-313F-HRTimelineGroup
Fortitude Family Office, LLC15$660<0.01%013F-HRTimeline
SJS Investment Consulting Inc.9$396<0.01%new13F-HRTimeline
CONTRAVISORY INVESTMENT MANAGEMENT, INC.6$264<0.01%new13F-HRTimeline
Integrated Wealth Concepts LLC6$264<0.01%new13F-HRTimeline
PNC Financial Services Group, Inc.in group PNC Financial Services Group,…5$220<0.01%-1113F-HRTimelineGroup
Steward Partners Investment Advisory, L…4$176<0.01%-25013F-HRTimeline
NATIONAL BANK OF CANADA /FI/in group NATIONAL BANK OF CANADA /FI/2$88<0.01%new13F-HRTimelineGroup
ROTHSCHILD INVESTMENT LLC1$44<0.01%013F-HRTimeline
Allworth Financial LP1$44<0.01%-2813F-HRTimeline