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13F-HR filed by RA CAPITAL MANAGEMENT, L.P.

RA CAPITAL MANAGEMENT, L.P. filed this 13F-HR for the quarter ended 2021-09-30, filed 2021-11-15, with 95 holding rows worth $7,216,742,000.

Accession
0001104659-21-139249
Filed
2021-11-15
Accepted by EDGAR
acceptance time not in the bulk data set
Ingested
Source
SEC quarterly data set

Original filing

13F report for Q3 2021

A holdings report, 95 entries on the cover page, a total value of $7,216,742,000 stated on the cover page (in dollars after the unit check, H1), rows summing to $7,216,744,000 with VALUE read as thousands by filing date, 13F file number 028-12884. The quarter's positions are built on this report. The resolved quarter.

The information table after summing rows of one CUSIP and put or call (H4), with the CUSIP and issuer name as filed. Values in dollars after the unit check (method).

Issuer as filedCUSIPClassAmountValueValue read asType
ASCENDIS PHARMA A/S DKK 1.0 AD04351P101SPONSORED ADR7,387,900$1,177,557,000thousands by filing date
NOVAVAX INC670002401COM NEW2,097,794$434,894,000thousands by filing date
CLIMB BIO INC28658R106COMMON STOCK13,150,849$236,452,000thousands by filing date
INVIVYD INC00534A102COMMON STOCK5,340,130$225,567,000thousands by filing date
FORMA THERAPEUTICS HLDGS INC34633R104SHS9,011,651$208,980,000thousands by filing date
CYTEK BIOSCIENCES INC23285D109COMMON STOCK9,607,028$205,686,000thousands by filing date
ATEA PHARMACEUTICALS INC04683R106COMMON STOCK5,427,655$190,294,000thousands by filing date
JANUX THERAPEUTICS INC47103J105COM8,670,644$187,546,000thousands by filing date
VOR BIOPHARMA INC929033108COM11,120,973$174,377,000thousands by filing date
AEROVATE THERAPEUTICS INC008064107COM8,263,982$173,378,000thousands by filing date
ICOSAVAX INC45114M109COM5,779,347$171,011,000thousands by filing date
DICE THERAPEUTICS INC23345J104COM5,208,911$170,592,000thousands by filing date
CONNECT BIOPHARMA HLDGS LTD207523101SHS6,991,003$169,392,000thousands by filing date
NKARTA INC65487U108COMMON STOCK5,605,129$155,879,000thousands by filing date
ACUMEN PHARMACEUTICALS INC00509G209CMN9,770,773$145,194,000thousands by filing date
TG THERAPEUTICS INC COM88322Q108Stock4,098,332$136,392,000thousands by filing date
TRAVERE THERAPEUTICS INC89422G107COM5,614,428$136,150,000thousands by filing date
TYRA BIOSCIENCES INC90240B106COMMON STOCK7,236,454$127,289,000thousands by filing date
MACROGENICS INC556099109COM5,943,594$124,459,000thousands by filing date
ITEOS THERAPEUTICS INC46565G104COM4,417,259$119,266,000thousands by filing date
Day One Biopharmaceuticals Inc23954D109Common Stock4,965,588$117,833,000thousands by filing date
IMMUNOGEN INC45253H101COMMON STOCK18,417,458$104,427,000thousands by filing date
PHATHOM PHARMACEUTICALS INC71722W107COMMON STOCK3,115,008$99,992,000thousands by filing date
VAXCYTE INC COM92243G108Stock3,896,865$98,863,000thousands by filing date
89BIO INC282559103COM4,965,769$97,279,000thousands by filing date
Instil Bio, Inc.45783C101Common Stock4,870,793$87,065,000thousands by filing date
CELLDEX THERAPEUTICS INC NEW15117B202COM NEW1,600,000$86,384,000thousands by filing date
KINNATE BIOPHARMA INC49705R105COM3,593,052$82,712,000thousands by filing date
WEREWOLF THERAPEUTICS INC95075A107CMN4,291,881$73,649,000thousands by filing date
TENAYA THERAPEUTICS INC87990A106COM3,551,508$73,339,000thousands by filing date
POINT BIOPHARMA GLOBAL INC730541109COM8,856,018$68,103,000thousands by filing date
GH RESEARCH PLC ORDINARY SHARESG3855L106Stock3,013,957$66,488,000thousands by filing date
RHYTHM PHARMACEUTICALS INC76243J105COM4,871,067$63,616,000thousands by filing date
ROCKET PHARMACEUTICALS INC77313F106COM2,107,149$62,983,000thousands by filing date
C4 THERAPEUTICS INC12529R107COM STK1,377,569$61,550,000thousands by filing date
CENTESSA PHARMACEUTICALS PLC152309100SPONSORED ADS3,577,094$59,737,000thousands by filing date
OLEMA PHARMACEUTICALS INC68062P106COM2,150,404$59,265,000thousands by filing date
CYTEIR THERAPEUTICS INC23284P103COMMON3,350,506$58,801,000thousands by filing date
PMV PHARMACEUTICALS INC69353Y103COM1,710,265$50,966,000thousands by filing date
ZOGENIX INC.98978L204Common Stock3,333,700$50,639,000thousands by filing date
DYNE THERAPEUTICS INC COM26818M108Stock2,805,045$45,554,000thousands by filing date
GRAPHITE BIO INC38870X104COM2,698,369$44,226,000thousands by filing date
EDGEWISE THERAPEUTICS INC28036F105COM2,613,623$43,386,000thousands by filing date
VERVE THERAPEUTICS INC92539P101COM880,284$41,373,000thousands by filing date
GERON CORP374163103COM30,126,299$41,273,000thousands by filing date
ACHILLES THERAPEUTICS PL-ADR00449L102COM5,014,687$39,064,000thousands by filing date
RXSIGHT INC78349D107COM3,052,796$38,679,000thousands by filing date
WAVE LIFE SCIENCES LTD SHSY95308105Stock7,775,207$38,099,000thousands by filing date
KALVISTA PHARMACEUTICALS INC483497103COM1,930,322$33,684,000thousands by filing date
DESIGN THERAPEUTICS INC25056L103COM2,186,636$32,122,000thousands by filing date
BOLT BIOTHERAPEUTICS INC097702104COM2,378,325$30,086,000thousands by filing date
SOLID BIOSCIENCES INC COM NEW83422E105Stock12,367,873$29,559,000thousands by filing date
TANGO THERAPEUTICS INC87583X109COM2,250,000$29,093,000thousands by filing date
KALA BIO INC COM483119103Stock10,874,613$28,491,000thousands by filing date
VERONA PHARMA PLC925050106SPONSORED ADS5,100,000$27,948,000thousands by filing date
SATSUMA PHARMACEUTICALS INC80405P107COM5,914,252$27,560,000thousands by filing date
AKOUOS INC00973J101COM2,281,249$26,485,000thousands by filing date
ORCHARD THERAPEUTICS PLC68570P101ADR11,028,722$25,366,000thousands by filing date
EYEPOINT INC COM NEW30233G209Stock2,210,506$23,033,000thousands by filing date
CENTURY THERAPEUTICS INC15673T100COM914,094$22,999,000thousands by filing date
BLACK DIAMOND THERAPEUTICS I09203E105COM2,589,904$21,911,000thousands by filing date
SYNLOGIC INC87166L100COM6,666,666$20,333,000thousands by filing date
SCPHARMACEUTICALS INC810648105COM2,731,170$18,162,000thousands by filing date
CYTOMX THERAPEUTICS INC23284F105COMMON STOCK3,500,000$17,815,000thousands by filing date
LARIMAR THERAPEUTICS INC517125100COM1,515,151$17,470,000thousands by filing date
ARS PHARMACEUTICALS INC82835W108COM1,742,186$17,387,000thousands by filing date
NAUTILUS BIOTECHNOLOGY INC63909J108COM2,436,430$14,960,000thousands by filing date
DA32 LIFE SCNCE TEC ACQSTN C23312M106CLASS A COM1,500,000$14,745,000thousands by filing date
Milestone Pharmaceuticals Inc59935V107COM2,246,503$12,828,000thousands by filing date
BCLS ACQUISITION CORPG0904B105CMN1,250,000$12,450,000thousands by filing date
ASTRIA THERAPEUTICS INC COM04635X102Stock1,262,193$11,158,000thousands by filing date
ENTERA BIO LTDM40527109SHS2,353,000$11,083,000thousands by filing date
Tscan Therapeutics Inc89854M101COM1,255,317$10,469,000thousands by filing date
AVIDITY BIOSCIENCES INC COM05370A108Stock423,616$10,434,000thousands by filing date
WHITEHAWK THERAPEUTICS INC00032Q104CMN347,668$10,211,000thousands by filing date
PARDES BIOSCIENCES INC COM30318F100Stock1,000,000$9,950,000thousands by filing date
CONCERT PHARMACEUTICALS INC206022105COM3,033,603$9,920,000thousands by filing date
ARYA SCIENCES ACQUISITN CORPG31658100CLASS A ORD SHS1,000,000$9,880,000thousands by filing date
FRAZIER LIFESCIENCES ACQU CORP UNIT EXP 120925G3710A121Stock1,000,000$9,820,000thousands by filing date
IKENA ONCOLOGY INC45175G108COM750,000$9,465,000thousands by filing date
PHASEBIO PHARMACEUTICALS INC717224109COM2,850,000$8,864,000thousands by filing date
CUE HEALTH INC229790100COM750,000$8,858,000thousands by filing date
COGENT BIOSCIENCES INC19240Q201COM1,025,641$8,626,000thousands by filing date
CULLINAN THERAPEUTICS INC230031106COM350,000$7,900,000thousands by filing date
OCULAR THERAPEUTIX INC67576A100COM750,000$7,500,000thousands by filing date
5 01 ACQUISITION CORP33836P105CMN750,000$7,365,000thousands by filing date
MOONLAKE IMMUNOTHERAPEUTICSG4444C102COM700,000$6,965,000thousands by filing date
HEALTH SCIENCES ACQ CORP 2G4411D109ORD SHS625,000$6,181,000thousands by filing date
BIOMEA FUSION INC09077A106CMN500,000$5,985,000thousands by filing date
CVRX INC126638105COMMON STOCK275,000$4,549,000thousands by filing date
SYROS PHARMACEUTICALS INC87184Q107COM900,000$4,023,000thousands by filing date
CHEMOCENTRYX INC16383L106COM218,532$3,737,000thousands by filing date
OTONOMY INC68906L105COM1,631,635$3,133,000thousands by filing date
RENEO PHARMACEUTICALS INC75974E103COM62,217$464,000thousands by filing date
VIRIDIAN THERAPEUTICS INC92790C104COM1,034$17,000thousands by filing date

Amendment chain

FilingRoleFiledAcceptedIngested
13F-HR 0001104659-21-139249this filing2021-11-15acceptance time not in the bulk data set