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Disclosery

TSHA TAYSHA GENE THERAPIES INC

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COMMON STOCK (common), issuer CIK 1806310

201 managers (209 13F filers) reported a position in TSHA shares at 2026-06-30, 299,577,796 shares in all. 41 filers opened a position and 22 filers sold out during the quarter.

Managers
201
13F filers
209
New
41
Added
98
Reduced
41
Sold out
22
Shares held by filers
299,577,796

Shares held by filers adds up every 13F filer's report, so a share reported by a parent and by its subsidiary counts twice (H9). Managers counts each filer group once.

13D and 13G filers

No 13D or 13G on this security in the data. Structured 13D/G data starts 2024-12-18.

Insider trades

No Form 4 transaction on this security in the data.

13F holders, Q2 2026

Filers in the available 13F reports with a share position at 2026-06-30, filer groups collapsed to one row (method), largest first. Options and principal amounts are left out. A group row states no % of portfolio, since each member reports its own portfolio: the members' percents are listed under it. A value about 1,000 times or 1/1,000 of the price other filers imply is shown as filed but neither ranks the row nor enters a sum.

HolderSharesValue% of portfolioChangeSource
Avoro Capital Advisors LLC23,888,888$163M1.46%+2,188,88813F-HRTimeline
RA CAPITAL MANAGEMENT, L.P.in group RA CAPITAL MANAGEMENT, L.P.23,555,648$160M1.39%013F-HRTimelineGroup
GOLDMAN SACHS GROUP INCin group GOLDMAN SACHS GROUP INC22,713,118$155M0.02%+343,47313F-HRTimelineGroup
BlackRock, Inc.in group BlackRock, Inc.20,691,927$141M<0.01%+2,326,31913F-HRTimelineGroup
Vestal Point Capital, LP19,415,000$132M3.09%+1,415,00013F-HRTimeline
VANGUARD GROUP INCgroup of 7 filers holding17,835,379$121M+3,794,894Timeline
MORGAN STANLEYin group MORGAN STANLEY16,487,479$112M0.01%-1,477,89213F-HRTimelineGroup
RTW INVESTMENTS, LP13,560,258$92.3M0.79%-119,99013F-HRTimeline
FMR LLCin group FMR LLC13,336,413$90.8M<0.01%-984,84213F-HRTimelineGroup
STATE STREET CORPin group STATE STREET CORP11,421,920$77.8M<0.01%+212,84213F-HRTimelineGroup
Siren, L.L.C.in group Siren, L.L.C.9,846,579$67.1M1.36%+1,016,66613F-HRTimelineGroup
Octagon Capital Advisors LP9,693,244$66M6.06%+833,33313F-HRTimeline
GEODE CAPITAL MANAGEMENT, LLCin group GEODE CAPITAL MANAGEMENT, LLC6,560,394$44.7M<0.01%+1,028,43913F-HRTimelineGroup
Polar Capital Holdings Plcin group Polar Capital Holdings Plc5,117,133$34.8M0.1%-537,20713F-HRTimelineGroup
MPM BIOIMPACT LLC4,500,000$30.6M1.87%new13F-HRTimeline
D. E. Shaw & Co., Inc.in group D. E. Shaw & Co., Inc.4,398,652$30M0.02%-28,64913F-HRTimelineGroup
BAKER BROS. ADVISORS LPin group BAKER BROS. ADVISORS LP4,004,756$27.3M0.14%013F-HRTimelineGroup
WELLINGTON MANAGEMENT GROUP LLPin group WELLINGTON MANAGEMENT GROUP L…3,975,605$27.1M<0.01%+3,349,24413F-HRTimelineGroup
HEALTHCARE OF ONTARIO PENSION PLAN TRUS…3,885,501$26.5M0.04%+1,002,20013F-HRTimeline
GordonMD Global Investments LPin group GordonMD Global Investments LP723,185$24.5M11.86%-14,36513F-HRTimelineGroup
Casdin Capital, LLC3,250,000$22.1M1.11%013F-HRTimeline
ADAR1 Capital Management, LLCin group ADAR1 Capital Management, LLC3,040,466$20.7M0.97%+61,03713F-HRTimelineGroup
Pictet Asset Management Holding SAin group Pictet Asset Management Holdi…2,770,701$18.9M0.02%+2,751,38313F-HRTimelineGroup
Aberdeen Group plcin group Aberdeen Group plc2,327,152$15.8M0.02%+1,306,08913F-HRTimelineGroup
FARALLON CAPITAL MANAGEMENT, L.L.C.2,250,000$15.3M0.09%new13F-HRTimeline
NORGES BANK2,233,600$15.2M<0.01%new13F-HRTimeline
NORTHERN TRUST CORPin group NORTHERN TRUST CORP2,226,210$15.2M<0.01%+411,89213F-HRTimelineGroup
CHARLES SCHWAB INVESTMENT MANAGEMENT INCin group Charles Schwab Trust Co2,200,695$15M<0.01%+392,09613F-HRTimelineGroup
MILLENNIUM MANAGEMENT LLCin group MILLENNIUM MANAGEMENT LLC2,126,838$14.5M0.01%-1,154,98213F-HRTimelineGroup
ORBIMED ADVISORS LLCin group ORBIMED ADVISORS LLC2,000,000$13.6M0.26%new13F-HRTimelineGroup
RICE HALL JAMES & ASSOCIATES, LLC1,992,229$13.6M0.66%+47,55813F-HRTimeline
B Group, Inc.1,800,556$12.3M6.96%013F-HRTimeline
Affinity Asset Advisors, LLC1,750,000$11.9M0.58%+750,00013F-HRTimeline
BARCLAYS PLCin group BARCLAYS PLC1,630,659$11.1M<0.01%-1,181,35113F-HRTimelineGroup
CITADEL ADVISORS LLCin group CITADEL ADVISORS LLC1,535,287$10.5M0.01%+1,124,15213F-HRTimelineGroup
HEIGHTS CAPITAL MANAGEMENT, INCin group HEIGHTS CAPITAL MANAGEMENT, I…1,500,000$10.2M2.36%new13F-HRTimelineGroup
Seven Fleet Capital Management LP1,504,400$9.94M1.64%+878,69213F-HRTimeline
Palo Alto Investors LP1,391,382$9.48M1.31%013F-HR/ATimeline
BANK OF AMERICA CORP /DE/in group BANK OF AMERICA CORP /DE/1,372,845$9.35M<0.01%-304,20113F-HRTimelineGroup
Granahan Investment Management, LLC1,305,177$8.89M0.32%+421,93613F-HRTimeline
UBS Group AGgroup of 2 filers holding861,027$5.86M+77,534Timeline
Quantum Private Wealth, LLC812,027$5.53M1.42%-37,18513F-HRTimeline
FIRST TRUST ADVISORS LPin group FIRST TRUST ADVISORS LP791,169$5.39M<0.01%new13F-HRTimelineGroup
JPMORGAN CHASE & COin group JPMORGAN CHASE & CO766,282$5.16M<0.01%+11,50013F-HRTimelineGroup
Sands Capital Alternatives, LLC724,873$4.94M0.8%013F-HRTimeline
Bank of New York Mellon Corpin group Bank of New York Mellon Corp697,971$4.75M<0.01%+89,84813F-HRTimelineGroup
BNP PARIBAS FINANCIAL MARKETSin group BNP PARIBAS FINANCIAL MARKETS640,035$4.36M<0.01%+519,83513F-HRTimelineGroup
PANAGORA ASSET MANAGEMENT INC590,387$4.02M0.01%+408,22313F-HRTimeline
AFFINITY WEALTH MANAGEMENT LLC576,808$3.93M0.51%new13F-HRTimeline
Squarepoint Ops LLCin group Squarepoint Ops LLC569,269$3.88M0.01%+158,98713F-HRTimelineGroup
ACUTA CAPITAL PARTNERS, LLC561,808$3.83M2.67%+122,34413F-HRTimeline
Nuveen, LLCin group TIAA555,693$3.78M<0.01%+6,54013F-HRTimelineGroup
ADAGE CAPITAL PARTNERS GP, L.L.C.in group ADAGE CAPITAL PARTNERS GP, L.…553,000$3.77M0.01%new13F-HRTimelineGroup
DIADEMA PARTNERS LP522,619$3.56M1.26%new13F-HRTimeline
Hennion & Walsh Asset Management, Inc.519,120$3.54M0.1%+127,64413F-HRTimeline
Woodline Partners LP513,828$3.5M0.01%013F-HRTimeline
Holocene Advisors, LP510,000$3.47M0.01%new13F-HRTimeline
Ghisallo Capital Management LLC505,000$3.44M0.07%new13F-HRTimeline
Burkehill Global Management, LP500,000$3.4M0.12%new13F-HRTimeline
POLEN CAPITAL MANAGEMENT LLC489,219$3.33M0.03%+169,47113F-HRTimeline
DIMENSIONAL FUND ADVISORS LPin group DIMENSIONAL FUND ADVISORS LP464,771$3.16M<0.01%-25,70113F-HRTimelineGroup
VOYA INVESTMENT MANAGEMENT LLCin group VOYA INVESTMENT MANAGEMENT LLC425,363$2.9M<0.01%-86,62013F-HRTimelineGroup
Trexquant Investment LP379,577$2.58M0.02%new13F-HRTimeline
Swiss National Bank369,000$2.51M<0.01%+100,20013F-HRTimeline
MOORE CAPITAL MANAGEMENT, LP358,374$2.44M0.06%+29,54313F-HRTimeline
WELLS FARGO & COMPANY/MNin group WELLS FARGO & COMPANY/MN333,314$2.27M<0.01%+149,98013F-HRTimelineGroup
Jefferies Financial Group Inc.in group Jefferies Financial Group Inc.328,800$2.24M0.02%-150,20013F-HRTimelineGroup
CITIGROUP INCin group CITIGROUP INC306,907$2.09M<0.01%+249,82713F-HRTimelineGroup
RHUMBLINE ADVISERS299,975$2.04M<0.01%+41,44513F-HRTimeline
ALPS ADVISORS INC290,543$1.98M0.01%+67,55713F-HRTimeline
Invesco Ltd.in group Invesco Ltd.264,379$1.8M<0.01%-103,64213F-HRTimelineGroup
Ensign Peak Advisors, Inc262,896$1.79M<0.01%-12,21513F-HRTimeline
Qube Research & Technologies Ltd259,605$1.77M<0.01%new13F-HRTimeline
SPHERA FUNDS MANAGEMENT LTD.in group SPHERA FUNDS MANAGEMENT LTD.250,000$1.7M0.24%new13F-HRTimelineGroup
DEUTSCHE BANK AG\in group DEUTSCHE BANK AG\243,379$1.66M<0.01%+61,61013F-HRTimelineGroup
TWO SIGMA INVESTMENTS, LPin group TWO SIGMA INVESTMENTS, LP234,716$1.6M<0.01%-507,36513F-HRTimelineGroup
JANE STREET GROUP, LLCin group JANE STREET GROUP, LLC228,355$1.56M<0.01%new13F-HRTimelineGroup
SG Americas Securities, LLC202,260$1.38M<0.01%-1,974,48213F-HRTimeline
Monashee Investment Management LLC200,000$1.36M2.29%new13F-HRTimeline
PRICE T ROWE ASSOCIATES INC /MD/199,494$1.36M<0.01%+40,54013F-HRTimeline
Privium Fund Management B.V.198,900$1.35M0.25%+17,00013F-HRTimeline
VICTORY CAPITAL MANAGEMENT INC197,578$1.35M<0.01%+1,83313F-HRTimeline
Chicago Partners Investment Group LLC222,347$1.3M0.03%+51,59613F-HRTimeline
Balyasny Asset Management L.P.in group Balyasny Asset Management189,332$1.29M<0.01%+106,31313F-HRTimelineGroup
STATE OF WISCONSIN INVESTMENT BOARD177,089$1.21M<0.01%-86,24313F-HRTimeline
CALIFORNIA STATE TEACHERS RETIREMENT SY…169,374$1.15M<0.01%+32,44113F-HR/ATimeline
RAYMOND JAMES FINANCIAL INCin group RAYMOND JAMES FINANCIAL INC166,042$1.13M<0.01%+144,01113F-HRTimelineGroup
ALLIANCEBERNSTEIN L.P.247,680$1.11M<0.01%+58,44013F-HRTimeline
WEXFORD CAPITAL LP160,654$1.09M0.15%013F-HRTimeline
Rafferty Asset Management, LLC154,706$1.05M<0.01%-145,19713F-HRTimeline
Palumbo Wealth Management LLC149,173$1.02M0.21%+2,46413F-HRTimeline
MetLife Investment Management, LLCin group MetLife Investment Management…140,846$959K<0.01%+20,73013F-HRTimelineGroup
Mirae Asset Global Investments Co., Ltd.group of 2 filers holding140,767$957K+1,750Timeline
Persistent Asset Partners Ltd133,411$909K0.29%new13F-HRTimeline
AQR CAPITAL MANAGEMENT LLCin group AQR CAPITAL MANAGEMENT LLC128,764$877K<0.01%-48,54513F-HRTimelineGroup
Mariner, LLCin group Mariner, LLC116,582$794K<0.01%new13F-HRTimelineGroup
Aquatic Capital Management LLC108,208$737K0.03%+68,35213F-HRTimeline
Legal & General Group Plcin group Legal & General Group Plc108,207$737K<0.01%+3,89913F-HRTimelineGroup
FRANKLIN RESOURCES INCin group Franklin Resources106,290$724K<0.01%-2,10913F-HRTimelineGroup
Engineers Gate Manager LP104,132$709K0.01%new13F-HRTimeline
MANUFACTURERS LIFE INSURANCE COMPANY, T…in group MANUFACTURERS LIFE INSURANCE …104,095$709K<0.01%+4,72413F-HRTimelineGroup
XTX Topco Ltdin group XTX Topco Ltd101,195$689K0.01%+90,86613F-HRTimelineGroup
PRELUDE CAPITAL MANAGEMENT, LLC98,346$670K0.05%new13F-HRTimeline
PROFUND ADVISORS LLC80,200$546K0.02%-54,47113F-HRTimeline
GSA CAPITAL PARTNERS LLP72,573$494K0.03%new13F-HRTimeline
Police & Firemen's Retirement System of…70,719$482K<0.01%+13,55113F-HRTimeline
NEW YORK STATE COMMON RETIREMENT FUND69,300$472K<0.01%+1,80013F-HRTimeline
Jupiter Topco LLCin group Janus Henderson69,000$470K<0.01%13F-HRTimelineGroup
J. Goldman & Co LP67,349$459K0.02%+33,59913F-HRTimeline
RED REEF ADVISORS LLC65,950$449K0.41%013F-HRTimeline
China Universal Asset Management Co., L…65,734$448K0.03%+17,12513F-HRTimeline
Creative Planningin group Creative Planning63,781$434K<0.01%+3,98013F-HRTimelineGroup
COMMONWEALTH EQUITY SERVICES, LLC61,773$421K<0.01%+3,33113F-HRTimeline
Russell Investments Group, Ltd.in group Russell Investments Group, Lt…61,705$420K<0.01%+44,77613F-HRTimelineGroup
OMERS ADMINISTRATION Corp59,100$402K<0.01%new13F-HRTimeline
Virtus Investment Advisers, LLCin group Virtus Investment Advisers, L…57,303$390K0.09%+10,20813F-HRTimelineGroup
LANARK FINANCIAL, INC.55,022$375K0.03%+96413F-HRTimeline
INTECH INVESTMENT MANAGEMENT LLC52,618$358K<0.01%+4,63013F-HRTimeline
Zurcher Kantonalbank (Zurich Cantonalba…49,213$335K<0.01%-31,56613F-HRTimeline
KLP KAPITALFORVALTNING AS47,800$326K<0.01%+18,50013F-HRTimeline
Militia Capital Management LLCin group Militia Capital Management LLC46,500$317K0.06%013F-HRTimelineGroup
State of New Jersey Common Pension Fund…in group State of New Jersey Common Pe…46,443$316K<0.01%-36413F-HRTimelineGroup
Williams & Novak, LLC45,000$306K0.2%013F-HRTimeline
Almanack Investment Partners, LLC.44,950$306K0.04%new13F-HRTimeline
FIRST MANHATTAN CO. LLC.43,500$296K<0.01%013F-HRTimeline
Mitsubishi UFJ Asset Management Co., Lt…in group Mitsubishi UFJ Trust & Bankin…43,191$294K<0.01%-13,38613F-HRTimelineGroup
ProShare Advisors LLC40,817$278K<0.01%-3,45013F-HRTimeline
ARIZONA STATE RETIREMENT SYSTEM39,633$270K<0.01%+2,01413F-HRTimeline
PRUDENTIAL FINANCIAL INCin group PRUDENTIAL FINANCIAL INC39,040$266K<0.01%+5,22013F-HRTimelineGroup
ENVESTNET ASSET MANAGEMENT INCin group ENVESTNET ASSET MANAGEMENT INC37,314$254K<0.01%+3,66013F-HRTimelineGroup
LOS ANGELES CAPITAL MANAGEMENT LLC32,149$219K<0.01%+3,63813F-HRTimeline
Cetera Investment Advisers31,607$215K<0.01%+3,15713F-HRTimeline
GUGGENHEIM CAPITAL LLCin group GUGGENHEIM CAPITAL LLC29,721$202K<0.01%+13,13613F-HRTimelineGroup
Allianz Asset Management GmbHin group Allianz SE42,400$190K<0.01%013F-HRTimelineGroup
SUSQUEHANNA INTERNATIONAL GROUP, LLPin group SUSQUEHANNA INTERNATIONAL GRO…27,164$185K<0.01%-89,13313F-HRTimelineGroup
Quadrature Capital Ltdin group Quadrature Capital Ltd25,753$175K<0.01%+2,25413F-HRTimelineGroup
nVerses Capital, LLC25,152$171K0.26%new13F-HRTimeline
State of Wyoming24,382$166K0.02%new13F-HRTimeline
XPONANCE LLC22,881$156K<0.01%+2,84813F-HRTimeline
E Fund Management Co., Ltd.21,814$149K<0.01%-15,88513F-HRTimeline
Ameritas Investment Partners, Inc.group of 2 filers holding21,761$148K+4,088Timeline
Lee Financial Co20,000$136K0.02%013F-HRTimeline
ALLSTATE CORPin group ALLSTATE CORP19,447$132K<0.01%new13F-HRTimelineGroup
Weiss Asset Management LPin group Weiss Asset Management LP19,144$130K<0.01%new13F-HRTimelineGroupThe filing omitted confidential holdings, a later amendment may add them.
Aster Capital Management (DIFC) Ltd18,553$126K0.03%new13F-HR/ATimeline
PRINCIPAL FINANCIAL GROUP INCin group PRINCIPAL FINANCIAL GROUP INC18,334$125K<0.01%+2,14913F-HRTimelineGroup
TEACHER RETIREMENT SYSTEM OF TEXAS16,736$114K<0.01%-1,04813F-HRTimeline
Cambridge Investment Research Advisors,…15,075$103K<0.01%-7,30513F-HR/ATimeline
Thrivent Financial for Lutheransin group Thrivent Financial for Luther…14,520$98K<0.01%new13F-HRTimelineGroup
ST GERMAIN D J CO INCin group ST GERMAIN D J CO INC14,133$96.2K<0.01%+4,50013F-HRTimelineGroup
SEI INVESTMENTS COin group SEI INVESTMENTS CO13,952$95K<0.01%-37,52013F-HRTimelineGroup
BANK OF MONTREAL /CAN/in group BANK OF MONTREAL /CAN/13,668$93.1K<0.01%013F-HRTimelineGroup
CAPTRUST FINANCIAL ADVISORS13,455$91.6K<0.01%new13F-HRTimeline
SIMPLEX TRADING, LLC13,371$91.1K<0.01%new13F-HRTimeline
CIBC Bancorp USA Inc.in group CIBC Bancorp USA Inc.13,262$90.3K<0.01%+2,14113F-HRTimelineGroup
Ethic Inc.12,512$85.2K<0.01%-47413F-HRTimeline
Tower Research Capital LLC (TRC)in group Tower Research Capital LLC (T…11,530$78.5K<0.01%-14,55413F-HRTimelineGroup
Magnetar Financial LLCin group Magnetar Financial LLC11,475$78.1K<0.01%+6613F-HRTimelineGroup
NEUBERGER BERMAN GROUP LLCin group NEUBERGER BERMAN GROUP LLC11,170$76.1K<0.01%+34713F-HRTimelineGroup
Summit Financial, LLC10,888$74.1K<0.01%-26013F-HRTimeline
CHOREO, LLC10,618$72.3K<0.01%+57413F-HRTimeline
Capital Investment Advisors, LLC10,000$68.1K<0.01%013F-HRTimeline
OSAIC HOLDINGS, INC.in group OSAIC HOLDINGS, INC.8,838$60.2K<0.01%+6,81813F-HRTimelineGroup
ROYAL BANK OF CANADAin group ROYAL BANK OF CANADA7,386$51K<0.01%+7,19513F-HRTimelineGroup
Allworth Financial LP6,978$47.5K<0.01%+1,53513F-HRTimeline
GF FUND MANAGEMENT CO. LTD.5,797$39.5K<0.01%-33113F-HRTimeline
NISA INVESTMENT ADVISORS, LLC5,780$39.4K<0.01%+67313F-HRTimeline
Rockefeller Capital Management L.P.in group Rockefeller Capital Managemen…5,000$34K<0.01%013F-HRTimelineGroup
SBI Securities Co., Ltd.3,065$20.9K<0.01%+3,05013F-HRTimeline
Steward Partners Investment Advisory, L…3,000$20.4K<0.01%new13F-HRTimeline
Pacer Advisors, Inc.2,584$18K<0.01%new13F-HRTimeline
Kemnay Advisory Services Inc.2,582$17.6K<0.01%new13F-HRTimeline
BNP PARIBAS ASSET MANAGEMENT Holding S.…in group BNP PARIBAS ASSET MANAGEMENT …2,099$14.3K<0.01%-35513F-HRTimelineGroup
Chung Wu Investment Group, LLC2,000$13.6K0.01%013F-HRTimeline
INTERNATIONAL ASSETS INVESTMENT MANAGEM…2,000$13.3K<0.01%013F-HRTimeline
GROUP ONE TRADING LLC1,939$13.2K<0.01%new13F-HRTimeline
Caitong International Asset Management …1,855$12.6K<0.01%+92913F-HRTimeline
JONES FINANCIAL COMPANIES LLLPin group JONES FINANCIAL COMPANIES LLLP1,461$9.26K<0.01%+90013F-HRTimelineGroup
Integrated Wealth Concepts LLC1,336$9.1K<0.01%new13F-HRTimeline
US BANCORP \DE\in group US BANCORP \DE\1,152$7.84K<0.01%+14513F-HRTimelineGroup
PNC Financial Services Group, Inc.in group PNC Financial Services Group,…1,053$7.17K<0.01%+1013F-HRTimelineGroup
Sterling Capital Management LLC842$5.73K<0.01%-56913F-HRTimeline
Federation des caisses Desjardins du Qu…500$3.4K<0.01%-4,50013F-HRTimeline
Quarry LP480$3.27K<0.01%new13F-HRTimeline
Larson Financial Group LLC469$3.19K<0.01%+34113F-HRTimeline
Optiver Holding B.V.in group Optiver Holding B.V.443$3.02K<0.01%-42113F-HRTimelineGroup
Arax Advisory Partners360$2.45K<0.01%new13F-HRTimeline
Essential Partners LLC327$2.23K<0.01%013F-HRTimeline
Parallel Advisors, LLC280$1.91K<0.01%-613F-HRTimeline
SIGNATUREFD, LLC266$1.81K<0.01%013F-HRTimeline
GAMMA Investing LLC232$1.58K<0.01%+9713F-HRTimeline
ROTHSCHILD INVESTMENT LLC170$1.16K<0.01%013F-HRTimeline
Covestor Ltd94$1K<0.01%+6713F-HRTimeline
Capital Advisors, Ltd. LLC79$1K<0.01%013F-HRTimeline
EverSource Wealth Advisors, LLCin group EverSource Wealth Advisors, L…141$960<0.01%013F-HRTimelineGroup
NATIONAL BANK OF CANADA /FI/in group NATIONAL BANK OF CANADA /FI/85$578<0.01%new13F-HRTimelineGroup
Farther Finance Advisors, LLC55$375<0.01%013F-HRTimeline
True Wealth Design, LLC30$205<0.01%013F-HRTimeline
Keating Financial Advisory Services, In…26$177<0.01%+1313F-HRTimeline
IFP Advisors, Inc14$95<0.01%013F-HRTimeline