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BAKER BROS. ADVISORS LP

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13F filer, CIK 1263508, NEW YORK, NY

BAKER BROS. ADVISORS LP reported $19,955,238,553 across 84 holdings for the quarter ended 2026-06-30, in a 13F-HR filed 2026-08-14. Its ten largest share positions make up 72.82% of the portfolio.

Filed (acceptance time not in the bulk data set), ingested 13F-HR 0001104659-26-097191

Period
2026-06-30
Reported value
$20B
Holdings
84
Top 10 weight
72.82%
New
9
Sold out
9

Part of the filer group BAKER BROS. ADVISORS LP

How groups are built

Largest buys vs the previous quarter

SecurityShares changeApprox. value
RVMDadded+1,888,000$354M
INSMadded+1,375,000$147M
IDYAadded+1,063,515$39.6M
FTHnew+1,286,411$32.2M
RLAYadded+1,666,666$31.2M

Ranked by the share change valued at this quarter's implied price (value over shares in the 13F). A position sold out is valued at the previous quarter's price, its last report.

Largest sells vs the previous quarter

SecurityShares changeApprox. value
EWTXreduced-2,874,221-$117M
ABVXexited-875,796-$97.5M
CELCUITY INCexited-30,750,000-$74.9M
SMMTreduced-3,604,715-$52.5M
SYREexited-1,000,000-$50.4M

Ranked by the share change valued at this quarter's implied price (value over shares in the 13F). A position sold out is valued at the previous quarter's price, its last report.

Holdings, Q2 2026

Share positions as resolved from 13F-HR 0001104659-26-097191, largest first. % of portfolio is the value over $19,955,238,553, the sum of the share positions whose value is usable for ratios (method).

SecurityHistorySharesValue% of portfolioChangeLatest eventTimeline
INCYINCYTE CORPQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: 30,739,020 shares; 2024Q4: 30,739,466 shares; 2025Q1: 30,739,953 shares; 2025Q2: 30,743,275 shares; 2025Q3: 30,743,663 shares; 2025Q4: 30,743,991 shares; 2026Q1: 30,744,412 shares; 2026Q2: 30,762,330 shares 30,762,330$3.49B17.48%+17,918Timeline
ONCBEONE MEDICINES LTDQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: 10,568,897 shares; 2024Q4: 9,531,880 shares; 2025Q1: 8,799,053 shares; 2025Q2: 8,799,053 shares; 2025Q3: 8,799,053 shares; 2025Q4: 8,799,053 shares; 2026Q1: 8,799,053 shares; 2026Q2: 8,801,567 shares 8,801,567$2.51B12.57%+2,514Timeline
RVMDREVOLUTION MEDICINES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: 7,569,090 shares; 2024Q4: 7,936,972 shares; 2025Q1: 7,936,972 shares; 2025Q2: 9,364,972 shares; 2025Q3: 9,455,357 shares; 2025Q4: 9,455,357 shares; 2026Q1: 9,555,357 shares; 2026Q2: 11,443,357 shares 11,443,357$2.14B10.74%+1,888,000Timeline
MDGLMADRIGAL PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: 1,974,590 shares; 2024Q4: 1,974,590 shares; 2025Q1: 1,974,590 shares; 2025Q2: 1,976,018 shares; 2025Q3: 2,141,701 shares; 2025Q4: 2,141,701 shares; 2026Q1: 2,141,701 shares; 2026Q2: 2,143,131 shares 2,143,131$1.15B5.77%+1,430Timeline
ACADACADIA PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: 42,877,916 shares; 2024Q4: 42,877,916 shares; 2025Q1: 42,877,916 shares; 2025Q2: 42,896,690 shares; 2025Q3: 42,896,690 shares; 2025Q4: 42,896,690 shares; 2026Q1: 42,896,690 shares; 2026Q2: 42,912,904 shares 42,912,904$1.09B5.44%+16,214Timeline
KYMRKYMERA THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: 5,995,929 shares; 2024Q4: 5,995,929 shares; 2025Q1: 5,995,929 shares; 2025Q2: 6,651,429 shares; 2025Q3: 6,651,429 shares; 2025Q4: 8,657,242 shares; 2026Q1: 8,657,242 shares; 2026Q2: 8,657,242 shares 8,657,242$993M4.97%0Timeline
INSMINSMED INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: 4,415,918 shares; 2024Q4: 5,006,863 shares; 2025Q1: 5,380,626 shares; 2025Q2: 7,712,900 shares; 2025Q3: 6,703,484 shares; 2025Q4: 6,592,746 shares; 2026Q1: 7,421,111 shares; 2026Q2: 8,796,111 shares 8,796,111$938M4.7%+1,375,000Timeline
CELCCELCUITY INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: 1,874,978 shares; 2024Q4: 2,678,553 shares; 2025Q1: 4,257,735 shares; 2025Q2: 5,450,445 shares; 2025Q3: 7,915,792 shares; 2025Q4: 7,915,792 shares; 2026Q1: 7,915,792 shares; 2026Q2: 7,915,792 shares 7,915,792$828M4.15%0Timeline
KODKODIAK SCIENCES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: 17,310,490 shares; 2024Q4: 17,310,490 shares; 2025Q1: 17,310,490 shares; 2025Q2: 17,310,490 shares; 2025Q3: 17,310,490 shares; 2025Q4: 19,919,186 shares; 2026Q1: 19,919,186 shares; 2026Q2: 19,919,186 shares 19,919,186$776M3.89%02026-09-28, 13D/A: 22,049,297 shares, 35% of the class, 13D/A filed 2026-09-30 Timeline
RYTMRHYTHM PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: 6,398,366 shares; 2024Q4: 6,084,249 shares; 2025Q1: 5,604,483 shares; 2025Q2: 5,604,483 shares; 2025Q3: 5,604,483 shares; 2025Q4: 5,604,483 shares; 2026Q1: 5,604,483 shares; 2026Q2: 5,604,483 shares 5,604,483$622M3.12%0Timeline
PRAXPRAXIS PRECISION MEDICINES IQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: 323,105 shares; 2024Q4: 331,533 shares; 2025Q1: 331,533 shares; 2025Q2: 689,488 shares; 2025Q3: 689,488 shares; 2025Q4: 1,126,488 shares; 2026Q1: 1,753,198 shares; 2026Q2: 1,753,198 shares 1,753,198$587M2.94%0Timeline
ALKSALKERMES PLCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: 4,181,751 shares; 2024Q4: 4,181,751 shares; 2025Q1: 4,483,285 shares; 2025Q2: 6,410,603 shares; 2025Q3: 8,091,351 shares; 2025Q4: 10,012,267 shares; 2026Q1: 10,012,267 shares; 2026Q2: 10,012,267 shares 10,012,267$525M2.63%0Timeline
SMMTSUMMIT THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: 24,424,865 shares; 2024Q4: 24,424,865 shares; 2025Q1: 24,424,865 shares; 2025Q2: 33,722,974 shares; 2025Q3: 33,722,974 shares; 2025Q4: 36,391,063 shares; 2026Q1: 36,391,063 shares; 2026Q2: 32,786,348 shares 32,786,348$478M2.39%-3,604,715Timeline
GRALGRAIL INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: not reported; 2024Q4: 1,630,125 shares; 2025Q1: 1,630,125 shares; 2025Q2: 1,630,125 shares; 2025Q3: 1,630,125 shares; 2025Q4: 2,085,333 shares; 2026Q1: 4,028,614 shares; 2026Q2: 4,028,614 shares 4,028,614$275M1.38%0Timeline
ABCLABCELLERA BIOLOGICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: 27,525,640 shares; 2024Q4: 27,525,640 shares; 2025Q1: 27,525,640 shares; 2025Q2: 27,525,640 shares; 2025Q3: 27,525,640 shares; 2025Q4: 27,525,640 shares; 2026Q1: 30,275,938 shares; 2026Q2: 33,012,138 shares 33,012,138$259M1.3%+2,736,200Timeline
IMVTIMMUNOVANT INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: 1,225,410 shares; 2024Q4: 1,707,881 shares; 2025Q1: 5,457,881 shares; 2025Q2: 5,457,881 shares; 2025Q3: 5,457,881 shares; 2025Q4: 5,457,881 shares; 2026Q1: 5,457,881 shares; 2026Q2: 5,435,220 shares 5,435,220$209M1.05%-22,661Timeline
IDYAIDEAYA BIOSCIENCES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: 1,062,123 shares; 2024Q4: 1,062,123 shares; 2025Q1: 1,062,123 shares; 2025Q2: 2,118,728 shares; 2025Q3: 3,275,444 shares; 2025Q4: 3,618,826 shares; 2026Q1: 3,946,515 shares; 2026Q2: 5,010,030 shares 5,010,030$187M0.94%+1,063,515Timeline
KNSAKINIKSA PHARMACEUTICALS INTLQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: 2,818,323 shares; 2024Q4: 2,818,323 shares; 2025Q1: 2,818,323 shares; 2025Q2: 2,824,669 shares; 2025Q3: 2,824,669 shares; 2025Q4: 2,826,246 shares; 2026Q1: 2,826,246 shares; 2026Q2: 2,834,643 shares 2,834,643$181M0.91%+8,397Timeline
ROIVROIVANT SCIENCES LTDQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: 2,798,716 shares; 2024Q4: 3,767,773 shares; 2025Q1: 3,767,773 shares; 2025Q2: 3,767,773 shares; 2025Q3: 3,767,773 shares; 2025Q4: 5,555,017 shares; 2026Q1: 4,867,723 shares; 2026Q2: 4,716,831 shares 4,716,831$167M0.84%-150,892Timeline
ARWRARROWHEAD PHARMACEUTICALS INQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 939,174 shares; 2025Q3: 1,670,762 shares; 2025Q4: 2,175,645 shares; 2026Q1: 1,992,783 shares; 2026Q2: 1,992,783 shares 1,992,783$162M0.81%0Timeline
IONSIONIS PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: 223,470 shares; 2024Q4: 357,915 shares; 2025Q1: 357,915 shares; 2025Q2: not reported; 2025Q3: 566,798 shares; 2025Q4: 1,791,841 shares; 2026Q1: 2,047,727 shares; 2026Q2: 2,047,727 shares 2,047,727$162M0.81%0Timeline
EWTXEDGEWISE THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: 5,840,059 shares; 2024Q4: 6,155,940 shares; 2025Q1: 6,155,940 shares; 2025Q2: 7,305,940 shares; 2025Q3: 7,305,940 shares; 2025Q4: 6,575,940 shares; 2026Q1: 6,575,940 shares; 2026Q2: 3,701,719 shares 3,701,719$150M0.75%-2,874,221Timeline
REPLREPLIMUNE GROUP INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: 11,045,336 shares; 2024Q4: 11,045,336 shares; 2025Q1: 11,045,336 shares; 2025Q2: 11,045,336 shares; 2025Q3: 11,045,336 shares; 2025Q4: 11,045,336 shares; 2026Q1: 11,045,336 shares; 2026Q2: 11,045,336 shares 11,045,336$122M0.61%0Timeline
NRIXNURIX THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: 3,882,125 shares; 2024Q4: 3,882,125 shares; 2025Q1: 3,882,125 shares; 2025Q2: 3,882,125 shares; 2025Q3: 3,882,125 shares; 2025Q4: 4,658,556 shares; 2026Q1: 4,658,556 shares; 2026Q2: 4,658,556 shares 4,658,556$113M0.57%0Timeline
STOKSTOKE THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: 4,368,443 shares; 2024Q4: 4,633,838 shares; 2025Q1: 4,633,838 shares; 2025Q2: 4,633,838 shares; 2025Q3: 4,633,838 shares; 2025Q4: 3,336,697 shares; 2026Q1: 3,336,697 shares; 2026Q2: 3,336,697 shares 3,336,697$109M0.55%0Timeline
GLUEMONTE ROSA THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: 4,916,095 shares; 2024Q4: 4,916,095 shares; 2025Q1: 4,916,095 shares; 2025Q2: 4,916,095 shares; 2025Q3: 4,916,095 shares; 2025Q4: 4,345,736 shares; 2026Q1: 4,345,736 shares; 2026Q2: 4,345,736 shares 4,345,736$105M0.53%0Timeline
IMTXIMMATICS N.VQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: 6,443,398 shares; 2024Q4: 7,275,830 shares; 2025Q1: 7,275,830 shares; 2025Q2: 10,168,901 shares; 2025Q3: 12,094,094 shares; 2025Q4: 12,094,094 shares; 2026Q1: 10,916,693 shares; 2026Q2: 9,508,565 shares 9,508,565$96.3M0.48%-1,408,128Timeline
DNLIDENALI THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: 3,731,695 shares; 2024Q4: 3,731,695 shares; 2025Q1: 3,731,695 shares; 2025Q2: 3,731,695 shares; 2025Q3: 3,731,695 shares; 2025Q4: 3,731,695 shares; 2026Q1: 3,731,695 shares; 2026Q2: 3,734,336 shares 3,734,336$96M0.48%+2,641Timeline
CRNXCRINETICS PHARMACEUTICALS INQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: 103,927 shares; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 280,000 shares; 2025Q3: 280,000 shares; 2025Q4: 1,648,869 shares; 2026Q1: 2,351,465 shares; 2026Q2: 2,351,465 shares 2,351,465$88M0.44%0Timeline
DNTHDIANTHUS THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 789,759 shares; 2025Q3: 789,759 shares; 2025Q4: 789,759 shares; 2026Q1: 852,164 shares; 2026Q2: 852,164 shares 852,164$83.1M0.42%0Timeline
GPCRSTRUCTURE THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: 85,500 shares; 2024Q4: 361,565 shares; 2025Q1: 361,565 shares; 2025Q2: 2,508,767 shares; 2025Q3: 1,556,109 shares; 2025Q4: 1,432,529 shares; 2026Q1: 1,432,529 shares; 2026Q2: 1,432,529 shares 1,432,529$76.9M0.39%0Timeline
RAPPRAPPORT THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 550,090 shares; 2025Q3: 1,547,090 shares; 2025Q4: 1,547,090 shares; 2026Q1: 1,547,090 shares; 2026Q2: 1,547,090 shares 1,547,090$64.5M0.32%0Timeline
ALMSALUMIS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: 1,562,500 shares; 2024Q4: 1,562,500 shares; 2025Q1: 1,562,500 shares; 2025Q2: 1,562,500 shares; 2025Q3: 1,562,500 shares; 2025Q4: 1,562,500 shares; 2026Q1: 2,012,500 shares; 2026Q2: 2,012,500 shares 2,012,500$56.6M0.28%0Timeline
PRLDPRELUDE THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: 10,123,824 shares; 2024Q4: 10,123,824 shares; 2025Q1: 10,123,824 shares; 2025Q2: 10,123,824 shares; 2025Q3: 10,123,824 shares; 2025Q4: 10,123,824 shares; 2026Q1: 10,123,824 shares; 2026Q2: 10,123,824 shares 10,123,824$54M0.27%0Timeline
RLAYRELAY THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: 1,160,117 shares; 2024Q4: 1,160,117 shares; 2025Q1: 1,160,117 shares; 2025Q2: 1,160,117 shares; 2025Q3: 1,160,117 shares; 2025Q4: 1,160,117 shares; 2026Q1: 1,160,117 shares; 2026Q2: 2,826,783 shares 2,826,783$52.9M0.27%+1,666,666Timeline
MIRMMIRUM PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: 190,476 shares; 2024Q4: 190,476 shares; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: not reported; 2026Q1: 445,975 shares; 2026Q2: 445,975 shares 445,975$52.2M0.26%0Timeline
BCYCBICYCLE THERAPEUTICS PLCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: 9,399,960 shares; 2024Q4: 10,885,357 shares; 2025Q1: 10,885,357 shares; 2025Q2: 10,885,357 shares; 2025Q3: 10,885,357 shares; 2025Q4: 10,885,357 shares; 2026Q1: 10,885,357 shares; 2026Q2: 10,885,357 shares 10,885,357$46.2M0.23%0Timeline
ELVNENLIVEN THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: 114,833 shares; 2024Q4: 114,833 shares; 2025Q1: 114,833 shares; 2025Q2: 114,833 shares; 2025Q3: 114,833 shares; 2025Q4: 271,406 shares; 2026Q1: 905,191 shares; 2026Q2: 905,191 shares 905,191$45.9M0.23%0Timeline
CLDXCELLDEX THERAPEUTICS INC NEWQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: 247,644 shares; 2024Q4: 247,644 shares; 2025Q1: 247,644 shares; 2025Q2: 665,370 shares; 2025Q3: 665,370 shares; 2025Q4: 665,370 shares; 2026Q1: 665,370 shares; 2026Q2: 1,182,611 shares 1,182,611$44M0.22%+517,241Timeline
VRDNVIRIDIAN THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 1,744,406 shares; 2025Q3: 1,744,406 shares; 2025Q4: 1,971,678 shares; 2026Q1: 1,971,678 shares; 2026Q2: 2,383,025 shares 2,383,025$43.8M0.22%+411,347Timeline
DSGNDESIGN THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: 1,743,725 shares; 2024Q4: 1,743,725 shares; 2025Q1: 1,743,725 shares; 2025Q2: 1,712,882 shares; 2025Q3: 1,712,882 shares; 2025Q4: 2,233,099 shares; 2026Q1: 2,585,978 shares; 2026Q2: 2,678,430 shares 2,678,430$38.8M0.19%+92,452Timeline
TRDAENTRADA THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: 4,865,819 shares; 2024Q4: 4,865,819 shares; 2025Q1: 4,865,819 shares; 2025Q2: 4,865,819 shares; 2025Q3: 4,865,819 shares; 2025Q4: 5,072,730 shares; 2026Q1: 5,072,730 shares; 2026Q2: 5,072,730 shares 5,072,730$37.3M0.19%0Timeline
FTHFAETH THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: not reported; 2026Q1: not reported; 2026Q2: 1,286,411 shares 1,286,411$32.2M0.16%newTimeline
AKTSAKTIS ONCOLOGY INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: not reported; 2026Q1: 996,351 shares; 2026Q2: 996,351 shares 996,351$32.1M0.16%0Timeline
NGNENEUROGENE INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: 456,015 shares; 2024Q4: 674,450 shares; 2025Q1: 1,486,200 shares; 2025Q2: 991,691 shares; 2025Q3: 991,691 shares; 2025Q4: 991,691 shares; 2026Q1: 991,691 shares; 2026Q2: 991,691 shares 991,691$31.2M0.16%0Timeline
JBIOJADE BIOSCIENCES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 1,641,137 shares; 2026Q1: 1,641,137 shares; 2026Q2: 1,230,426 shares 1,230,426$27.3M0.14%-410,711Timeline
TSHATAYSHA GENE THERAPIES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: 4,004,756 shares; 2024Q4: 4,004,756 shares; 2025Q1: 4,004,756 shares; 2025Q2: 4,004,756 shares; 2025Q3: 4,004,756 shares; 2025Q4: 4,004,756 shares; 2026Q1: 4,004,756 shares; 2026Q2: 4,004,756 shares 4,004,756$27.3M0.14%0Timeline
RCUSARCUS BIOSCIENCES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 270,000 shares; 2026Q1: 415,621 shares; 2026Q2: 844,816 shares 844,816$26M0.13%+429,195Timeline
IRONDISC MEDICINE INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: not reported; 2024Q4: 77,050 shares; 2025Q1: 77,050 shares; 2025Q2: 337,050 shares; 2025Q3: 337,050 shares; 2025Q4: 337,050 shares; 2026Q1: 349,657 shares; 2026Q2: 349,657 shares 349,657$25.6M0.13%0Timeline
ABSIABSCI CORPORATIONQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 2,134,803 shares; 2026Q1: 2,134,803 shares; 2026Q2: 2,134,803 shares 2,134,803$24.7M0.12%0Timeline
GENBGENERATE BIOMEDICINES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: not reported; 2026Q1: 1,423,602 shares; 2026Q2: 1,423,602 shares 1,423,602$24M0.12%0Timeline
DBVTDBV TECHNOLOGIES S AQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: not reported; 2024Q4: 1,461,425 shares; 2025Q1: 1,461,425 shares; 2025Q2: 1,461,425 shares; 2025Q3: 1,461,425 shares; 2025Q4: 1,461,425 shares; 2026Q1: 1,461,425 shares; 2026Q2: 1,461,425 shares 1,461,425$24M0.12%0Timeline
XENEXENON PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: 993,679 shares; 2024Q4: 993,679 shares; 2025Q1: 347,408 shares; 2025Q2: 370,208 shares; 2025Q3: 370,208 shares; 2025Q4: 370,208 shares; 2026Q1: 370,208 shares; 2026Q2: 370,208 shares 370,208$22.3M0.11%0Timeline
TECXTECTONIC THERAPEUTIC INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: 100,000 shares; 2025Q2: 100,000 shares; 2025Q3: 100,000 shares; 2025Q4: 903,400 shares; 2026Q1: 607,788 shares; 2026Q2: 607,788 shares 607,788$20.9M0.1%0Timeline
CERSCERUS CORPQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: 19,477,339 shares; 2024Q4: 19,477,339 shares; 2025Q1: 19,351,087 shares; 2025Q2: 12,883,844 shares; 2025Q3: 10,008,345 shares; 2025Q4: 10,008,345 shares; 2026Q1: 10,008,345 shares; 2026Q2: 6,395,431 shares 6,395,431$18.7M0.09%-3,612,914Timeline
CTMXCYTOMX THERAPEUTICS INC.Quarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 3,484,226 shares; 2025Q3: 4,250,826 shares; 2025Q4: 4,250,826 shares; 2026Q1: 4,975,826 shares; 2026Q2: 4,975,826 shares 4,975,826$18.7M0.09%0Timeline
DYNDYNE THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: 672,096 shares; 2024Q4: 672,096 shares; 2025Q1: 672,096 shares; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 813,449 shares; 2026Q1: 813,449 shares; 2026Q2: 813,449 shares 813,449$18.1M0.09%0Timeline
CYTKCYTOKINETICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: not reported; 2026Q1: not reported; 2026Q2: 211,267 shares 211,267$18M0.09%newTimeline
XNCRXENCOR INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: 670,431 shares; 2024Q4: 670,431 shares; 2025Q1: 670,431 shares; 2025Q2: 670,431 shares; 2025Q3: 1,102,106 shares; 2025Q4: 1,102,106 shares; 2026Q1: 1,102,106 shares; 2026Q2: 1,102,106 shares 1,102,106$17.7M0.09%0Timeline
SIONSIONNA THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: 400,000 shares; 2025Q2: 400,000 shares; 2025Q3: 400,000 shares; 2025Q4: 400,000 shares; 2026Q1: 400,000 shares; 2026Q2: 400,000 shares 400,000$17.6M0.09%0Timeline
NTLAINTELLIA THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: not reported; 2024Q4: 644,116 shares; 2025Q1: 644,116 shares; 2025Q2: 2,675,674 shares; 2025Q3: 2,746,674 shares; 2025Q4: not reported; 2026Q1: not reported; 2026Q2: 930,232 shares 930,232$15.7M0.08%newTimeline
PBLSPARABILIS MEDICINES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: not reported; 2026Q1: not reported; 2026Q2: 500,000 shares 500,000$13.7M0.07%newTimeline
MPLTMAPLIGHT THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 364,705 shares; 2026Q1: 364,705 shares; 2026Q2: 364,705 shares 364,705$13.1M0.07%0Timeline
AVLNAVALYN PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: not reported; 2026Q1: not reported; 2026Q2: 350,000 shares 350,000$11.5M0.06%newTimeline
EVMNEVOMMUNE INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: not reported; 2026Q1: 847,390 shares; 2026Q2: 847,390 shares 847,390$11.3M0.06%0Timeline
BNTXBIONTECH SEQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: not reported; 2024Q4: 45,031 shares; 2025Q1: 45,031 shares; 2025Q2: 368,923 shares; 2025Q3: 368,923 shares; 2025Q4: 368,923 shares; 2026Q1: 119,743 shares; 2026Q2: 119,743 shares 119,743$11.1M0.06%0Timeline
TNGXTANGO THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: 750,000 shares; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: not reported; 2026Q1: not reported; 2026Q2: 333,333 shares 333,333$10.4M0.05%newTimeline
AVTXAVALO THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: not reported; 2026Q1: not reported; 2026Q2: 550,000 shares 550,000$10.2M0.05%newTimeline
SERASERA PROGNOSTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: 5,434,399 shares; 2024Q4: 5,434,399 shares; 2025Q1: 5,498,170 shares; 2025Q2: 5,498,170 shares; 2025Q3: 5,498,170 shares; 2025Q4: 5,498,170 shares; 2026Q1: 5,498,170 shares; 2026Q2: 5,498,170 shares 5,498,170$10M0.05%0Timeline
VSTMVERASTEM INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: not reported; 2026Q1: 584,757 shares; 2026Q2: 2,499,338 shares 2,499,338$9.55M0.05%+1,914,581Timeline
SGMTSAGIMET BIOSCIENCES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: 1,381,898 shares; 2024Q4: 952,996 shares; 2025Q1: 952,996 shares; 2025Q2: 952,996 shares; 2025Q3: 952,996 shares; 2025Q4: 952,996 shares; 2026Q1: 952,996 shares; 2026Q2: 952,996 shares 952,996$7.37M0.04%0Timeline
EIKNEIKON THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: not reported; 2026Q1: 555,555 shares; 2026Q2: 555,555 shares 555,555$7.25M0.04%0Timeline
LBRXLB PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 200,000 shares; 2025Q4: 200,000 shares; 2026Q1: 200,000 shares; 2026Q2: 200,000 shares 200,000$6.49M0.03%0Timeline
VTVTVTV THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: 97,314 shares; 2024Q4: 97,314 shares; 2025Q1: 97,314 shares; 2025Q2: 97,314 shares; 2025Q3: 148,314 shares; 2025Q4: 148,314 shares; 2026Q1: 148,314 shares; 2026Q2: 148,314 shares 148,314$5.58M0.03%0Timeline
WVEWAVE LIFE SCIENCES LTDQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: 344,063 shares; 2024Q4: 344,063 shares; 2025Q1: 344,063 shares; 2025Q2: 344,063 shares; 2025Q3: 344,063 shares; 2025Q4: 344,063 shares; 2026Q1: 822,638 shares; 2026Q2: 822,638 shares 822,638$4.78M0.02%0Timeline
TARAPROTARA THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: 536,832 shares; 2024Q4: 536,832 shares; 2025Q1: 536,832 shares; 2025Q2: 536,832 shares; 2025Q3: 536,832 shares; 2025Q4: 971,614 shares; 2026Q1: 971,614 shares; 2026Q2: 971,614 shares 971,614$3.71M0.02%0Timeline
TCRXTSCAN THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: 2,784,792 shares; 2024Q4: 2,784,792 shares; 2025Q1: 2,784,792 shares; 2025Q2: 2,784,792 shares; 2025Q3: 2,784,792 shares; 2025Q4: 2,784,792 shares; 2026Q1: 2,784,792 shares; 2026Q2: 2,784,792 shares 2,784,792$2.73M0.01%0Timeline
IMNMIMMUNOME INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: not reported; 2026Q1: not reported; 2026Q2: 55,306 shares 55,306$1.17M0.01%newTimeline
SKYESKYE BIOSCIENCE INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: 1,434,634 shares; 2024Q4: 1,450,638 shares; 2025Q1: 1,450,638 shares; 2025Q2: 1,450,638 shares; 2025Q3: 1,450,638 shares; 2025Q4: 1,450,638 shares; 2026Q1: 1,575,243 shares; 2026Q2: 1,575,243 shares 1,575,243$1.09M0.01%0Timeline
SANASANA BIOTECHNOLOGY INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: 2,380,949 shares; 2024Q4: 2,380,949 shares; 2025Q1: 2,030,949 shares; 2025Q2: 2,030,949 shares; 2025Q3: 2,030,949 shares; 2025Q4: 310,483 shares; 2026Q1: 310,483 shares; 2026Q2: 310,483 shares 310,483$1.08M0.01%0Timeline
ALGSALIGOS THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: 83,055 shares; 2024Q4: 83,055 shares; 2025Q1: 83,055 shares; 2025Q2: 83,055 shares; 2025Q3: 83,055 shares; 2025Q4: 83,055 shares; 2026Q1: 83,055 shares; 2026Q2: 83,055 shares 83,055$479K<0.01%0Timeline
TYRATYRA BIOSCIENCES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: 10,607 shares; 2024Q4: 10,607 shares; 2025Q1: 10,607 shares; 2025Q2: 10,607 shares; 2025Q3: 10,607 shares; 2025Q4: 10,607 shares; 2026Q1: 10,607 shares; 2026Q2: 10,607 shares 10,607$339K<0.01%0Timeline
SRZNWSURROZEN INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q3: 833,333 shares; 2024Q4: 833,333 shares; 2025Q1: 833,333 shares; 2025Q2: 833,333 shares; 2025Q3: 833,333 shares; 2025Q4: 833,333 shares; 2026Q1: 833,333 shares; 2026Q2: 833,333 shares 833,333$13.8K<0.01%0Timeline

Principal amounts

Notes and convertibles filed as a face amount (PRN). A face amount is never added to a share count (H6).

SecurityTypeAmountValueChange
CELCUITY INCCELCUITY INC NOTE 2.750% 8/0principal30,750,000$69.2Mnew

Sold out in Q2 2026

Positions in the previous quarter's report that this quarter's report no longer lists.

SecurityShares beforeValue beforeType
ABVXABIVAX SA875,796$97.5Mshares
CELCUITY INCCELCUITY INC30,750,000$74.9Mshares
SYRESPYRE THERAPEUTICS INC1,000,000$50.4Mshares
CNTACENTESSA PHARMACEUTICALS PLC670,751$26.6Mshares
IMCRIMMUNOCORE HLDGS PLC734,397$22.1Mshares
CTNMCONTINEUM THERAPEUTICS INC1,420,838$18.6Mshares
ARGXARGENX SE25,174$18.4Mshares
CMPSCOMPASS PATHWAYS PLC2,344,720$13Mshares
PHVSPHARVARIS N V375,000$10.6Mshares

How Q2 2026 was built

Available 13F filings of this filer for the quarter and their roles: the base report is the latest original or restatement, NEW HOLDINGS amendments filed after it are added (method).

FilingRoleAmendmentFiledAcceptedIngested
13F-HR 0001104659-26-097191 base2026-08-14acceptance time not in the bulk data set

Filings

Every filing of this filer: 13F reports and notices, the 13D and 13G it filed or is a reporting person of, and Forms 3, 4 and 5 it reported as an owner.

FilingSubjectFiledAcceptedIngested
Form 4 0001193125-26-412653 INCYTE CORP2026-10-02
13D/A 0001104659-26-112371 KOD2026-09-30
Form 4 0001193125-26-409127 Kodiak Sciences Inc.2026-09-30
Form 4 0001193125-26-409118 Kodiak Sciences Inc.2026-09-30
Form 4 0001193125-26-409116 Kodiak Sciences Inc.2026-09-30
13F-HR 0001104659-26-097191 Quarter ended 2026-06-302026-08-14acceptance time not in the bulk data set
13F-HR 0001104659-26-062547 Quarter ended 2026-03-312026-05-15acceptance time not in the bulk data set
13F-HR 0001104659-26-016374 Quarter ended 2025-12-312026-02-17acceptance time not in the bulk data set
13F-HR 0001104659-25-112595 Quarter ended 2025-09-302025-11-14acceptance time not in the bulk data set
13F-HR 0001104659-25-078573 Quarter ended 2025-06-302025-08-14acceptance time not in the bulk data set
13F-HR 0001104659-25-049518 Quarter ended 2025-03-312025-05-15acceptance time not in the bulk data set
13F-HR 0001104659-25-014085 Quarter ended 2024-12-312025-02-14acceptance time not in the bulk data set
13F-HR 0001104659-24-118899 Quarter ended 2024-09-302024-11-14acceptance time not in the bulk data set
13F-HR 0001104659-24-089606 Quarter ended 2024-06-302024-08-14acceptance time not in the bulk data set
13F-HR 0001104659-24-061996 Quarter ended 2024-03-312024-05-15acceptance time not in the bulk data set
13F-HR 0001104659-24-024053 Quarter ended 2023-12-312024-02-14acceptance time not in the bulk data set
13F-HR 0001104659-23-118157 Quarter ended 2023-09-302023-11-14acceptance time not in the bulk data set
13F-HR 0001104659-23-091343 Quarter ended 2023-06-302023-08-14acceptance time not in the bulk data set
13F-HR 0001104659-23-060720 Quarter ended 2023-03-312023-05-15acceptance time not in the bulk data set
13F-HR 0001104659-23-021551 Quarter ended 2022-12-312023-02-14acceptance time not in the bulk data set
13F-HR 0001104659-22-118527 Quarter ended 2022-09-302022-11-14acceptance time not in the bulk data set
13F-HR 0001104659-22-091286 Quarter ended 2022-06-302022-08-15acceptance time not in the bulk data set
13F-HR 0001104659-22-061288 Quarter ended 2022-03-312022-05-16acceptance time not in the bulk data set
13F-HR 0001104659-22-022725 Quarter ended 2021-12-312022-02-14acceptance time not in the bulk data set
13F-HR 0001104659-21-139109 Quarter ended 2021-09-302021-11-15acceptance time not in the bulk data set
13F-HR 0001104659-21-106314 Quarter ended 2021-06-302021-08-16acceptance time not in the bulk data set
13F-HR 0001104659-21-068025 Quarter ended 2021-03-312021-05-17acceptance time not in the bulk data set
13F-HR 0001104659-21-023833 Quarter ended 2020-12-312021-02-16acceptance time not in the bulk data set
13F-HR 0001104659-20-125767 Quarter ended 2020-09-302020-11-16acceptance time not in the bulk data set
13F-HR 0001104659-20-095518 Quarter ended 2020-06-302020-08-14acceptance time not in the bulk data set
13F-HR 0001104659-20-062575 Quarter ended 2020-03-312020-05-15acceptance time not in the bulk data set
13F-HR 0001104659-20-021838 Quarter ended 2019-12-312020-02-14acceptance time not in the bulk data set
13F-HR 0001104659-19-064169 Quarter ended 2019-09-302019-11-14acceptance time not in the bulk data set
13F-HR 0001144204-19-040033 Quarter ended 2019-06-302019-08-14acceptance time not in the bulk data set
13F-HR 0001144204-19-026555 Quarter ended 2019-03-312019-05-15acceptance time not in the bulk data set
13F-HR 0001144204-19-007156 Quarter ended 2018-12-312019-02-13acceptance time not in the bulk data set
13F-HR 0001144204-18-059891 Quarter ended 2018-09-302018-11-14acceptance time not in the bulk data set
13F-HR 0001144204-18-044607 Quarter ended 2018-06-302018-08-14acceptance time not in the bulk data set
13F-HR 0001144204-18-028818 Quarter ended 2018-03-312018-05-15acceptance time not in the bulk data set
13F-HR 0001144204-18-008839 Quarter ended 2017-12-312018-02-14acceptance time not in the bulk data set
13F-HR 0001144204-17-058963 Quarter ended 2017-09-302017-11-14acceptance time not in the bulk data set
13F-HR 0001144204-17-043086 Quarter ended 2017-06-302017-08-14acceptance time not in the bulk data set
13F-HR 0001144204-17-027430 Quarter ended 2017-03-312017-05-15acceptance time not in the bulk data set
13F-HR 0001144204-17-008836 Quarter ended 2016-12-312017-02-14acceptance time not in the bulk data set
13F-HR 0001144204-16-134352 Quarter ended 2016-09-302016-11-14acceptance time not in the bulk data set
13F-HR 0001144204-16-119409 Quarter ended 2016-06-302016-08-15acceptance time not in the bulk data set
13F-HR 0001144204-16-102596 Quarter ended 2016-03-312016-05-16acceptance time not in the bulk data set
13F-HR 0001144204-16-082790 Quarter ended 2015-12-312016-02-16acceptance time not in the bulk data set
13F-HR 0001144204-15-065993 Quarter ended 2015-09-302015-11-16acceptance time not in the bulk data set
13F-HR 0001144204-15-049845 Quarter ended 2015-06-302015-08-14acceptance time not in the bulk data set
13F-HR 0001144204-15-031569 Quarter ended 2015-03-312015-05-15acceptance time not in the bulk data set
13F-HR 0001144204-15-010112 Quarter ended 2014-12-312015-02-17acceptance time not in the bulk data set
13F-HR 0001144204-14-068894 Quarter ended 2014-09-302014-11-14acceptance time not in the bulk data set
13F-HR 0001144204-14-050184 Quarter ended 2014-06-302014-08-14acceptance time not in the bulk data set
13F-HR 0001144204-14-031196 Quarter ended 2014-03-312014-05-15acceptance time not in the bulk data set
13F-HR 0001144204-14-009842 Quarter ended 2013-12-312014-02-14acceptance time not in the bulk data set
13F-HR 0001144204-13-061913 Quarter ended 2013-09-302013-11-14acceptance time not in the bulk data set
13F-HR 0001144204-13-045967 Quarter ended 2013-06-302013-08-14acceptance time not in the bulk data set