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Disclosery

DSGN DESIGN THERAPEUTICS INC

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COM (common), issuer CIK 1807120

130 managers (137 13F filers) reported a position in DSGN shares at 2026-06-30, 43,301,255 shares in all. 28 filers opened a position and 16 filers sold out during the quarter.

Managers
130
13F filers
137
New
28
Added
61
Reduced
32
Sold out
16
Shares held by filers
43,301,255

Shares held by filers adds up every 13F filer's report, so a share reported by a parent and by its subsidiary counts twice (H9). Managers counts each filer group once.

13D and 13G filers

No 13D or 13G on this security in the data. Structured 13D/G data starts 2024-12-18.

Insider trades

No Form 4 transaction on this security in the data.

13F holders, Q2 2026

Filers in the available 13F reports with a share position at 2026-06-30, filer groups collapsed to one row (method), largest first. Options and principal amounts are left out. A group row states no % of portfolio, since each member reports its own portfolio: the members' percents are listed under it. A value about 1,000 times or 1/1,000 of the price other filers imply is shown as filed but neither ranks the row nor enters a sum.

HolderSharesValue% of portfolioChangeSource
SR One Capital Management, LP6,526,476$94.4M9.09%013F-HRTimeline
Logos Global Management LP3,000,000$43.4M1.87%+1,050,00013F-HRTimeline
BAKER BROS. ADVISORS LPin group BAKER BROS. ADVISORS LP2,678,430$38.8M0.19%+92,45213F-HRTimelineGroup
Driehaus Capital Management LLC2,661,115$38.5M0.22%+916,12813F-HRTimeline
BlackRock, Inc.in group BlackRock, Inc.2,660,024$38.5M<0.01%+526,26013F-HRTimelineGroup
Point72 Asset Management, L.P.in group Point72 Asset Management, L.P.2,366,453$34.2M0.05%-356,30113F-HRTimelineGroup
VANGUARD GROUP INCgroup of 4 filers holding2,088,200$30.2M+392,288Timeline
Trails Edge Capital Partners, LP2,001,282$29M4.6%+1,149,26913F-HRTimeline
Frazier Life Sciences Management, L.P.1,809,854$26.2M0.57%new13F-HRTimeline
Vivo Capital, LLC1,612,903$23.3M2.13%013F-HRTimeline
Caption Management, LLC1,118,098$16.2M0.57%+1,031,39013F-HRTimeline
Almitas Capital LLC1,026,893$14.9M3.56%-503,44213F-HRTimeline
GEODE CAPITAL MANAGEMENT, LLCin group GEODE CAPITAL MANAGEMENT, LLC958,417$13.9M<0.01%+265,89913F-HRTimelineGroup
Sofinnova Investments, Inc.865,135$12.5M0.67%new13F-HRTimeline
FMR LLCin group FMR LLC776,462$11.2M<0.01%-21,94913F-HRTimelineGroup
MORGAN STANLEYin group MORGAN STANLEY765,425$11.1M<0.01%+108,86013F-HRTimelineGroup
STATE STREET CORPin group STATE STREET CORP736,221$10.7M<0.01%+76,64613F-HRTimelineGroup
Woodline Partners LP700,354$10.1M0.03%-261,14713F-HRTimeline
DIMENSIONAL FUND ADVISORS LPin group DIMENSIONAL FUND ADVISORS LP694,743$10.1M<0.01%+262,90313F-HRTimelineGroup
GOLDMAN SACHS GROUP INCin group GOLDMAN SACHS GROUP INC656,584$9.5M<0.01%+151,86613F-HRTimelineGroup
JACOBS LEVY EQUITY MANAGEMENT, INC565,597$8.18M0.03%+276,21213F-HRTimeline
ACADIAN ASSET MANAGEMENT LLCin group ACADIAN ASSET MANAGEMENT LLC537,479$7.77M0.01%-79,00213F-HRTimelineGroup
Siren, L.L.C.in group Siren, L.L.C.523,212$7.57M0.15%new13F-HRTimelineGroup
Qube Research & Technologies Ltd437,079$6.32M0.01%+402,89613F-HRTimeline
RENAISSANCE TECHNOLOGIES LLC387,913$5.61M0.01%-20,28713F-HRTimeline
KENNEDY CAPITAL MANAGEMENT LLC384,036$5.56M0.1%+112,48213F-HRTimeline
NORTHERN TRUST CORPin group NORTHERN TRUST CORP353,197$5.11M<0.01%+52,91813F-HRTimelineGroup
ALGERT GLOBAL LLC296,085$4.28M0.05%+91,34613F-HRTimeline
ACUTA CAPITAL PARTNERS, LLC282,564$4.09M2.85%+136,66413F-HRTimeline
CHARLES SCHWAB INVESTMENT MANAGEMENT INCin group Charles Schwab Trust Co271,264$3.93M<0.01%+29,77913F-HRTimelineGroup
PRUDENTIAL FINANCIAL INCin group PRUDENTIAL FINANCIAL INC224,170$3.24M<0.01%+178,36013F-HRTimelineGroup
D. E. Shaw & Co., Inc.in group D. E. Shaw & Co., Inc.195,645$2.83M<0.01%-274,62513F-HRTimelineGroup
Eversept Partners, LP190,000$2.75M0.15%new13F-HRTimeline
KVP Capital Advisors, LP185,000$2.68M1.96%new13F-HRTimeline
J. Goldman & Co LP176,770$2.56M0.09%new13F-HRTimeline
MILLENNIUM MANAGEMENT LLCin group MILLENNIUM MANAGEMENT LLC147,714$2.14M<0.01%+38,78613F-HRTimelineGroup
RAYMOND JAMES FINANCIAL INCin group RAYMOND JAMES FINANCIAL INC138,521$2M<0.01%+30,07213F-HRTimelineGroup
Balyasny Asset Management L.P.in group Balyasny Asset Management111,103$1.61M<0.01%new13F-HRTimelineGroup
Elmind Capital, LP107,900$1.56M0.39%-100,00013F-HRTimeline
Nuveen, LLCin group TIAA104,734$1.52M<0.01%-22,08113F-HRTimelineGroup
DAFNA Capital Management LLC102,600$1.48M0.28%new13F-HRTimeline
Bank of New York Mellon Corpin group Bank of New York Mellon Corp92,069$1.33M<0.01%+12,42413F-HRTimelineGroup
China Universal Asset Management Co., L…89,940$1.3M0.08%+54,83113F-HRTimeline
CITADEL ADVISORS LLCin group CITADEL ADVISORS LLC81,971$1.19M<0.01%-149,54213F-HRTimelineGroup
SummitTX Capital, L.P.80,663$1.17M0.03%new13F-HRTimeline
AMERICAN CENTURY COMPANIES INCin group AMERICAN CENTURY COMPANIES INC76,825$1.11M<0.01%+11,18713F-HRTimelineGroup
Palumbo Wealth Management LLC71,744$1.04M0.22%+33613F-HRTimeline
AQR CAPITAL MANAGEMENT LLCin group AQR CAPITAL MANAGEMENT LLC71,114$1.03M<0.01%+45,15713F-HRTimelineGroup
AMERIPRISE FINANCIAL INCin group AMERIPRISE FINANCIAL INC67,598$978K<0.01%+32,60813F-HRTimelineGroup
Russell Investments Group, Ltd.in group Russell Investments Group, Lt…66,859$967K<0.01%+41,42213F-HRTimelineGroup
ALPS ADVISORS INC63,391$917K<0.01%+13,18213F-HRTimeline
SUSQUEHANNA INTERNATIONAL GROUP, LLPgroup of 3 filers holding61,578$891KnewTimeline
STATE OF WISCONSIN INVESTMENT BOARD59,249$857K<0.01%+10,03513F-HRTimeline
STRS OHIO50,500$731K<0.01%+5,80013F-HRTimeline
Verdad Advisers, LP47,557$688K0.66%-44,75313F-HRTimeline
BANK OF AMERICA CORP /DE/in group BANK OF AMERICA CORP /DE/43,728$633K<0.01%+20,46413F-HRTimelineGroup
ExodusPoint Capital Management, LP41,286$597K0.01%new13F-HRTimeline
RHUMBLINE ADVISERS38,132$552K<0.01%+3,27213F-HRTimeline
UBS Group AGgroup of 2 filers holding35,904$520K+17,670Timeline
TWO SIGMA INVESTMENTS, LPin group TWO SIGMA INVESTMENTS, LP32,925$476K<0.01%+16,62513F-HRTimelineGroup
CANADA PENSION PLAN INVESTMENT BOARD32,600$472K<0.01%-27,80013F-HRTimeline
OPPENHEIMER & CO INCin group OPPENHEIMER ASSET MANAGEMENT …32,087$464K<0.01%new13F-HRTimelineGroup
ALLIANCEBERNSTEIN L.P.43,230$460K<0.01%-2,89013F-HRTimeline
DEUTSCHE BANK AG\in group DEUTSCHE BANK AG\30,613$443K<0.01%+9,96913F-HRTimelineGroup
Virtus Investment Advisers, LLCin group Virtus Investment Advisers, L…29,827$432K0.1%new13F-HRTimelineGroup
Squarepoint Ops LLCin group Squarepoint Ops LLC29,630$429K<0.01%-56,48713F-HRTimelineGroup
Trexquant Investment LP28,150$407K<0.01%-88,96113F-HRTimeline
WELLS FARGO & COMPANY/MNin group WELLS FARGO & COMPANY/MN28,072$406K<0.01%+19,04513F-HRTimelineGroup
Corient Private Wealth LPin group Corient Private Wealth LP27,169$393K<0.01%013F-HR/ATimelineGroup
BRIDGEWAY CAPITAL MANAGEMENT, LLC27,000$391K0.01%-25,00013F-HRTimeline
Quantinno Capital Management LP26,901$389K<0.01%+12,77313F-HRTimeline
PRICE T ROWE ASSOCIATES INC /MD/25,606$371K<0.01%+9,23613F-HRTimeline
SEI INVESTMENTS COin group SEI INVESTMENTS CO22,740$329K<0.01%-110,46313F-HRTimelineGroup
XTX Topco Ltdin group XTX Topco Ltd22,383$324K<0.01%-38,55613F-HRTimelineGroup
AlphaCentric Advisors LLC21,537$312K0.26%+30613F-HRTimeline
Invesco Ltd.in group Invesco Ltd.21,429$310K<0.01%-120,49113F-HRTimelineGroup
PUBLIC EMPLOYEES RETIREMENT SYSTEM OF O…20,700$300K<0.01%+5,50713F-HRTimeline
MetLife Investment Management, LLCin group MetLife Investment Management…20,609$298K<0.01%+5,36013F-HRTimelineGroup
WELLINGTON MANAGEMENT GROUP LLPin group WELLINGTON MANAGEMENT GROUP L…19,400$281K<0.01%new13F-HRTimelineGroup
Mirae Asset Global Investments Co., Ltd.group of 2 filers holding16,964$245K+2,630Timeline
JPMORGAN CHASE & COin group JPMORGAN CHASE & CO16,904$241K<0.01%+2,77013F-HRTimelineGroup
CITIGROUP INCin group CITIGROUP INC15,880$230K<0.01%+11,61713F-HRTimelineGroup
Creative Planningin group Creative Planning15,844$229K<0.01%new13F-HRTimelineGroup
NISA INVESTMENT ADVISORS, LLC14,824$215K<0.01%013F-HRTimeline
Y-Intercept (Hong Kong) Ltd12,910$187K<0.01%new13F-HRTimeline
ROYAL BANK OF CANADAin group ROYAL BANK OF CANADA12,254$178K<0.01%+88813F-HRTimelineGroup
BARCLAYS PLCin group BARCLAYS PLC11,707$169K<0.01%-44,08313F-HRTimelineGroup
NEW YORK STATE COMMON RETIREMENT FUND10,826$157K<0.01%+8,80013F-HRTimeline
GSA CAPITAL PARTNERS LLP10,328$149K0.01%new13F-HRTimeline
Police & Firemen's Retirement System of…9,849$143K<0.01%+3,25113F-HRTimeline
BNP PARIBAS FINANCIAL MARKETSin group BNP PARIBAS FINANCIAL MARKETS5,751$83.2K<0.01%-44,52113F-HRTimelineGroup
Clearstead Advisors, LLC5,610$81.2K<0.01%+5,00013F-HRTimeline
Tower Research Capital LLC (TRC)in group Tower Research Capital LLC (T…4,908$71K<0.01%+3,36313F-HRTimelineGroup
Rockefeller Capital Management L.P.in group Rockefeller Capital Managemen…3,684$53.3K<0.01%013F-HRTimelineGroup
CAZ INVESTMENTS LP3,500$50.6K0.02%013F-HR/ATimeline
Zurcher Kantonalbank (Zurich Cantonalba…3,025$43.8K<0.01%+1,43113F-HRTimeline
Legal & General Group Plcin group Legal & General Group Plc2,987$43.2K<0.01%+91013F-HRTimelineGroup
Ameritas Investment Partners, Inc.in group Ameritas Investment Partners,…2,793$40.4K<0.01%+22313F-HRTimelineGroup
State of Wyoming2,566$37.1K<0.01%new13F-HRTimeline
PNC Financial Services Group, Inc.in group PNC Financial Services Group,…1,816$26.3K<0.01%013F-HRTimelineGroup
GAMMA Investing LLC1,450$21K<0.01%-2213F-HRTimeline
Caitong International Asset Management …1,259$18.2K<0.01%+1,25813F-HRTimeline
GF FUND MANAGEMENT CO. LTD.1,209$17.5K<0.01%-6213F-HRTimeline
Allied Private Wealth LLC880$13.4K0.01%13F-HRTimeline
Private Wealth Management Group, LLC533$7.71K<0.01%013F-HRTimeline
CALIFORNIA STATE TEACHERS RETIREMENT SY…335$4.85K<0.01%-95713F-HR/ATimeline
Physician Wealth Advisors, Inc.268$3.88K<0.01%013F-HRTimeline
MassMutual Private Wealth & Trust, FSB239$3.46K<0.01%013F-HRTimeline
Stone House Investment Management, LLC239$3.46K<0.01%013F-HRTimeline
OSAIC HOLDINGS, INC.in group OSAIC HOLDINGS, INC.225$3.25K<0.01%-8113F-HRTimelineGroup
Larson Financial Group LLC181$2.62K<0.01%013F-HRTimeline
Arax Advisory Partners180$2.61K<0.01%new13F-HRTimeline
SIMPLEX TRADING, LLC172$2.49K<0.01%new13F-HRTimeline
Optiver Holding B.V.in group Optiver Holding B.V.160$2.31K<0.01%-6413F-HRTimelineGroup
Sterling Capital Management LLC108$1.56K<0.01%-68313F-HRTimeline
Allworth Financial LP96$1.39K<0.01%-3413F-HRTimeline
Versant Capital Management, Inc86$1.24K<0.01%new13F-HRTimeline
NATIONAL BANK OF CANADA /FI/in group NATIONAL BANK OF CANADA /FI/83$1.2K<0.01%+7413F-HRTimelineGroup
Silver Grove Financial Group, Inc.58$839<0.01%new13F-HRTimeline
Quarry LP31$449<0.01%new13F-HRTimeline
Integrated Wealth Concepts LLC27$390<0.01%new13F-HRTimeline
US BANCORP \DE\in group US BANCORP \DE\26$376<0.01%-3513F-HRTimelineGroup
EverSource Wealth Advisors, LLCin group EverSource Wealth Advisors, L…25$362<0.01%+1513F-HRTimelineGroup
ROTHSCHILD INVESTMENT LLC22$318<0.01%-113F-HRTimeline
Farther Finance Advisors, LLC20$289<0.01%-36613F-HRTimeline
True Wealth Design, LLC18$261<0.01%+1713F-HRTimeline
SBI Securities Co., Ltd.10$145<0.01%new13F-HRTimeline
SJS Investment Consulting Inc.4$58<0.01%new13F-HRTimeline
Essential Partners LLC1$14<0.01%013F-HRTimeline
Capital Advisors, Ltd. LLC12$00%013F-HRTimelineValue filed as zero, left out of ratios.