13F-HR filed by BAKER BROS. ADVISORS LP
BAKER BROS. ADVISORS LP filed this 13F-HR for the quarter ended 2013-12-31, filed 2014-02-14, with 95 holding rows worth $7,095,729,000.
- Accession
- 0001144204-14-009842
- Filer
- CIK 1263508
- Filed
- 2014-02-14
- Accepted by EDGAR
- acceptance time not in the bulk data set
- Ingested
- Source
- SEC quarterly data set
13F report for Q4 2013
A holdings report, 95 entries on the cover page, a total value of $7,095,729,000 stated on the cover page (in dollars after the unit check, H1), rows summing to $7,095,729,000 with VALUE read as thousands by filing date, 13F file number 028-10519. The quarter's positions are built on this report. The resolved quarter.
The information table after summing rows of one CUSIP and put or call (H4), with the CUSIP and issuer name as filed. Values in dollars after the unit check (method).
| Issuer as filed | CUSIP | Class | Amount | Value | Value read as | Type |
|---|---|---|---|---|---|---|
| PHARMACYCLICS INC | 716933106 | COM | 8,719,218 | $922,319,000 | thousands by filing date | |
| SEATTLE GENETICS INC | 812578102 | COM | 20,735,926 | $827,156,000 | thousands by filing date | |
| INCYTE CORP COM | 45337C102 | Stock | 14,810,559 | $749,859,000 | thousands by filing date | |
| SYNAGEVA BIOPHARMA CORP | 87159A103 | COM | 10,273,182 | $664,880,000 | thousands by filing date | |
| ACADIA PHARMACEUTICALS INC | 004225108 | COM | 19,955,126 | $498,679,000 | thousands by filing date | |
| SALIX PHARMACEUTICALS INC SR NT CONV DTD 6/3/2010 2.75% 5/15/2015 | 795435AC0 | CONVERTIBLE | 219,440,000 | $431,748,000 | thousands by filing date | principal |
| GENOMIC HEALTH, INC. | 37244C101 | COM | 13,650,835 | $399,560,000 | thousands by filing date | |
| Incyte Corporation | 45337CAL6 | NOTE 1.25% 11/15/2020 | 274,500,000 | $333,004,000 | thousands by filing date | principal |
| Incyte Corporation | 45337CAK8 | NOTE 0.375% 11/15/2018 | 259,000,000 | $310,045,000 | thousands by filing date | principal |
| Incyte Genomics Notes 4.75% 10/1/2015 | 45337CAH5 | CONV BONDS | 40,446,000 | $233,032,000 | thousands by filing date | principal |
| XOMA CORP DEL | 98419J107 | COM | 23,032,372 | $155,008,000 | thousands by filing date | |
| BIOMARIN PHARMACEUTICAL INC | 09061G101 | COM | 1,941,304 | $136,571,000 | thousands by filing date | |
| AUXILIUM PHARMACEUTICALS INC | 05334DAA5 | NOTE 1.500% 7/1 | 87,090,000 | $96,343,000 | thousands by filing date | principal |
| HALOZYME THERAPEUTICS INC COM | 40637H109 | Stock | 6,297,026 | $94,392,000 | thousands by filing date | |
| BIOMARIN PHARMACEUTICAL INC | 09061GAD3 | CNV | 22,898,000 | $79,367,000 | thousands by filing date | principal |
| GILEAD SCIENCES INC | 375558AP8 | CORPORATE OBLIG | 21,500,000 | $70,910,000 | thousands by filing date | principal |
| VANDA PHARMACEUTICALS INC | 921659108 | COM | 4,791,179 | $59,459,000 | thousands by filing date | |
| MEDIVATION INC | 58501NAA9 | NOTE | 39,500,000 | $57,806,000 | thousands by filing date | principal |
| INTERMUNE INC | 45884XAF0 | NOTE 2.500%12/1 | 41,000,000 | $56,157,000 | thousands by filing date | principal |
| CERUS CORP | 157085101 | COM | 8,455,306 | $54,537,000 | thousands by filing date | |
| BIOCRYST PHARMACEUTICALS INC COM | 09058V103 | Stock | 6,699,979 | $50,920,000 | thousands by filing date | |
| REPROS THERAPEUTICS INC | 76028H209 | COM | 2,778,654 | $50,849,000 | thousands by filing date | |
| QUESTCOR PHARMACEUTICALS INC | 74835Y101 | COM | 775,864 | $42,246,000 | thousands by filing date | |
| ANACOR PHARMACEUTICALS INC | 032420101 | COM | 2,500,000 | $41,950,000 | thousands by filing date | |
| Gilead Sciences,Inc. | 375558103 | COM | 556,108 | $41,764,000 | thousands by filing date | |
| MIRATI THERAPEUTICS INC | 60468T105 | COM | 2,380,074 | $39,581,000 | thousands by filing date | |
| AEGERION PHARMACEUTICALS INC | 00767E102 | COM | 500,000 | $35,480,000 | thousands by filing date | |
| ARROWHEAD RESEARCH CORP | 042797209 | COM | 3,090,000 | $33,527,000 | thousands by filing date | |
| CLOVIS ONCOLOGY INC | 189464100 | COM | 530,738 | $31,988,000 | thousands by filing date | |
| DERMA SCIENCES INC | 249827502 | COM PAR $.01 | 2,558,857 | $27,687,000 | thousands by filing date | |
| CHELSEA THERAPEUTICS INTL LT | 163428105 | COM | 5,794,753 | $25,700,000 | thousands by filing date | |
| MEDIVATION INC | 58501N101 | COM | 398,331 | $25,421,000 | thousands by filing date | |
| INTERCEPT PHARMACEUTICALS IN | 45845P108 | COM | 362,847 | $24,775,000 | thousands by filing date | |
| PROGENICS PHARMACEUTICALS IN | 743187106 | COM | 4,200,000 | $22,386,000 | thousands by filing date | |
| SALIX PHARMACEUTICAL 1.500 | 795435AE6 | NOTE 1.500% 3/ | 15,000,000 | $22,369,000 | thousands by filing date | principal |
| Intermune Inc Notes 5% 3/1/15 | 45884XAD5 | CONV BONDS | 16,860,000 | $19,526,000 | thousands by filing date | principal |
| AVANIR PHARMACEUTICALS INC | 05348P401 | CL A NEW | 5,428,591 | $18,240,000 | thousands by filing date | |
| DYAX CORP | 26746E103 | COM | 2,026,537 | $15,270,000 | thousands by filing date | |
| SYNERGY PHARMACEUTICALS DEL | 871639308 | COM NEW | 2,608,271 | $14,685,000 | thousands by filing date | |
| IDERA PHARMACEUTICALS INC | 45168K306 | COM | 3,171,765 | $14,685,000 | thousands by filing date | |
| INSMED INC COM PAR $.01 | 457669307 | Stock | 796,378 | $13,538,000 | thousands by filing date | |
| BIOMARIN PHARMACEUTICAL INC | 09061GAE1 | NOTE 0.750%10/1 | 12,500,000 | $13,262,000 | thousands by filing date | principal |
| STEMLINE THERAPEUTICS INC | 85858C107 | COM | 675,042 | $13,231,000 | thousands by filing date | |
| KYTHERA BIOPHARMACEUTICALS I | 501570105 | COM | 313,191 | $11,698,000 | thousands by filing date | |
| ISIS PHARMACEUTICALS INC | 464330109 | COM | 247,036 | $9,842,000 | thousands by filing date | |
| ZOGENIX INC | 98978L105 | COM | 2,751,000 | $9,463,000 | thousands by filing date | |
| PROTHENA CORP PLC SHS | G72800108 | Stock | 336,918 | $8,935,000 | thousands by filing date | |
| Infinity Pharmaceuticals Inc. | 45665303 | COM | 643,256 | $8,883,000 | thousands by filing date | The CUSIP as filed is malformed. |
| THRESHOLD PHARMACEUTICAL INC | 885807206 | COM NEW | 1,852,399 | $8,651,000 | thousands by filing date | |
| TG THERAPEUTICS INC COM | 88322Q108 | Stock | 2,199,656 | $8,579,000 | thousands by filing date | |
| QLT INC | 746927102 | COMMON STOCK | 1,535,863 | $8,555,000 | thousands by filing date | |
| DISCOVERY LABORATORIES INC N | 254668403 | COM NEW | 3,718,617 | $8,367,000 | thousands by filing date | |
| ARRAY BIOPHARMA INC COM | 04269X105 | Stock | 1,500,000 | $7,515,000 | thousands by filing date | |
| AMBIT BIOSCIENCES CORP | 02318X100 | COM | 747,954 | $7,210,000 | thousands by filing date | |
| OMEROS CORP | 682143102 | COM | 608,404 | $6,869,000 | thousands by filing date | |
| NOVAVAX INC | 670002104 | COMMON STOCK | 1,286,913 | $6,589,000 | thousands by filing date | |
| IRONWOOD PHARMACEUTICALS INC | 46333X108 | COMMON STOCK | 546,160 | $6,341,000 | thousands by filing date | |
| OSIRIS THERAPEUTICS INC NEW | 68827R108 | COM | 375,282 | $6,035,000 | thousands by filing date | |
| XENOPORT INC | 98411C100 | COM | 1,034,112 | $5,946,000 | thousands by filing date | |
| SANGAMO THERAPEUTICS INC | 800677106 | COM | 424,308 | $5,894,000 | thousands by filing date | |
| PORTOLA PHARMACEUTICALS INC COM | 737010108 | Stock | 224,434 | $5,779,000 | thousands by filing date | |
| AERIE PHARMACEUTICALS INC | 00771V108 | COM | 300,000 | $5,388,000 | thousands by filing date | |
| XENCOR INC | 98401F105 | COMMON STOCK | 550,000 | $5,027,000 | thousands by filing date | |
| BIODELIVERY SCIENCES INTL IN | 09060J106 | COM | 846,005 | $4,983,000 | thousands by filing date | |
| AGIOS PHARMACEUTICALS INC | 00847X104 | COM | 205,750 | $4,928,000 | thousands by filing date | |
| BIOTA PHARMACEUTIALS INC | 090694100 | COM | 1,130,113 | $4,735,000 | thousands by filing date | |
| VENTRUS BIOSCIENCES INC | 922822101 | COM | 1,215,840 | $4,645,000 | thousands by filing date | |
| EPIZYME INC | 29428V104 | COM | 220,000 | $4,576,000 | thousands by filing date | |
| TEKMIRA PHARMACEUTICALS COR | 87911B209 | COM NEW | 500,000 | $3,985,000 | thousands by filing date | |
| GW PHARMACEUTICALS PLC | 36197T103 | ADS | 94,172 | $3,912,000 | thousands by filing date | |
| LIGAND PHARMACEUTICALS INC | 53220K207 | COM | 73,400 | $3,861,000 | thousands by filing date | |
| OPHTHOTECH CORP | 683745103 | COM | 103,040 | $3,333,000 | thousands by filing date | |
| ENANTA PHARMACEUTICALS INC | 29251M106 | COM | 109,097 | $2,976,000 | thousands by filing date | |
| RECEPTOS, INC. | 756207106 | COMMON STOCK | 100,000 | $2,899,000 | thousands by filing date | |
| MACROGENICS INC | 556099109 | COM | 100,000 | $2,743,000 | thousands by filing date | |
| Synta Pharmaceuticals Corp. | 87162T206 | COM | 500,000 | $2,620,000 | thousands by filing date | |
| PUMA BIOTECHNOLOGY INC | 74587V107 | COMMON STOCK | 25,000 | $2,588,000 | thousands by filing date | |
| BLUEBIRD BIO INC | 09609G100 | COM | 114,461 | $2,401,000 | thousands by filing date | |
| UNITED THERAPEUTICS CORP DEL COM | 91307C102 | Stock | 20,000 | $2,262,000 | thousands by filing date | |
| INTERMUNE INC | 45884X103 | COM | 150,000 | $2,210,000 | thousands by filing date | |
| GERON CORP | 374163103 | COM | 402,629 | $1,908,000 | thousands by filing date | |
| ORASURE TECHNOLOGIES INC | 68554V108 | COM | 243,467 | $1,531,000 | thousands by filing date | |
| ACHILLION PHARMACEUTICALS IN | 00448Q201 | COM | 455,000 | $1,510,000 | thousands by filing date | |
| RIGEL PHARMACEUTICALS INC | 766559603 | COMMON STOCK | 500,000 | $1,425,000 | thousands by filing date | |
| KARYOPHARM THERAPEUTICS INC | 48576U106 | COM | 61,330 | $1,406,000 | thousands by filing date | |
| AMICUS THERAPEUTICS INC | 03152W109 | COM | 515,072 | $1,210,000 | thousands by filing date | |
| ACCELERON PHARMA INC | 00434H108 | COM | 30,000 | $1,188,000 | thousands by filing date | |
| ZIOPHARM ONCOLOGY INC | 98973P101 | COM | 254,199 | $1,103,000 | thousands by filing date | |
| TESARO INC | 881569107 | COM | 31,218 | $882,000 | thousands by filing date | |
| GALECTIN THERAPEUTICS INC | 363225202 | COMMON STOCK | 100,600 | $813,000 | thousands by filing date | |
| Foundation Medicine Inc | 350465100 | COM | 20,000 | $476,000 | thousands by filing date | |
| FIVE PRIME THERAPEUTICS INC. | 33830X104 | Common Stock | 19,823 | $333,000 | thousands by filing date | |
| SALIX PHARMACEUTICALS INC | 795435106 | COM | 3,621 | $326,000 | thousands by filing date | |
| CHEMOCENTRYX INC | 16383L106 | COM | 50,000 | $290,000 | thousands by filing date | |
| BIO GREEN MED SOL 6pcnt PFDCONV | 23254L207 | COMMON STOCK | 20,979 | $193,000 | thousands by filing date |
Amendment chain
| Filing | Role | Filed | Accepted | Ingested |
|---|---|---|---|---|
| 13F-HR 0001144204-14-009842 | this filing | 2014-02-14 | acceptance time not in the bulk data set |