Flagship Pioneering, LLC in group Flagship Pioneering, LLC More: the full row for Flagship Pioneering, LLC 62,673,117 $1.06B 68.66% 0 13F-HR Timeline Group FMR LLC in group FMR LLC More: the full row for FMR LLC 5,221,599 $88.1M <0.01% +1,004,075 13F-HR Timeline Group Capital World Investors More: the full row for Capital World Investors 4,215,632 $71.1M 0.01% +211,483 13F-HR Timeline BRAIDWELL LP More: the full row for BRAIDWELL LP 3,283,844 $55.4M 2.05% -309,155 13F-HR Timeline PRICE T ROWE ASSOCIATES INC /MD/ More: the full row for PRICE T ROWE ASSOCIATES INC /MD/ 2,156,627 $36.4M <0.01% +46,994 13F-HR Timeline NORGES BANK More: the full row for NORGES BANK 2,094,616 $35.3M <0.01% new 13F-HR Timeline ARCH Venture Management, LLC More: the full row for ARCH Venture Management, LLC 1,944,426 $32.8M 2.98% 0 13F-HR Timeline HarbourVest Partners LLC More: the full row for HarbourVest Partners LLC 1,722,210 $29.1M 17.09% 0 13F-HR Timeline BlackRock, Inc. in group BlackRock, Inc. More: the full row for BlackRock, Inc. 1,659,966 $28M <0.01% new 13F-HR Timeline Group VANGUARD GROUP INC group of 4 filers holding More: the full row for VANGUARD GROUP INC 1,486,479 $25.1M +1,336,479 Timeline BAKER BROS. ADVISORS LP in group BAKER BROS. ADVISORS LP More: the full row for BAKER BROS. ADVISORS LP 1,423,602 $24M 0.12% 0 13F-HR Timeline Group JPMORGAN CHASE & CO in group JPMORGAN CHASE & CO More: the full row for JPMORGAN CHASE & CO 1,409,649 $23.8M <0.01% -1,537,610 13F-HR Timeline Group Deep Track Capital, LP More: the full row for Deep Track Capital, LP 1,333,815 $22.5M 0.33% new 13F-HR Timeline ARK Investment Management LLC More: the full row for ARK Investment Management LLC 1,284,617 $21.7M 0.14% +786,209 13F-HR Timeline HARVARD MANAGEMENT CO INC More: the full row for HARVARD MANAGEMENT CO INC 1,111,100 $18.7M 0.44% 0 13F-HR Timeline NVIDIA CORP More: the full row for NVIDIA CORP 833,325 $14.1M 0.02% 0 13F-HR Timeline Davern Capital Partners, LP More: the full row for Davern Capital Partners, LP 824,679 $13.9M 2.37% +232,879 13F-HR Timeline Siren, L.L.C. in group Siren, L.L.C. More: the full row for Siren, L.L.C. 736,104 $12.4M 0.25% 0 13F-HR Timeline Group GEODE CAPITAL MANAGEMENT, LLC in group GEODE CAPITAL MANAGEMENT, LLC More: the full row for GEODE CAPITAL MANAGEMENT, LLC 735,003 $12.4M <0.01% +616,760 13F-HR Timeline Group STATE STREET CORP in group STATE STREET CORP More: the full row for STATE STREET CORP 526,565 $8.88M <0.01% new 13F-HR Timeline Group Affinity Asset Advisors, LLC More: the full row for Affinity Asset Advisors, LLC 400,000 $6.75M 0.33% +50,000 13F-HR Timeline MORGAN STANLEY in group MORGAN STANLEY More: the full row for MORGAN STANLEY 377,994 $6.38M <0.01% +40,692 13F-HR Timeline Group UBS Group AG in group UBS Group AG More: the full row for UBS Group AG 326,273 $5.5M <0.01% -30,431 13F-HR Timeline Group SPHERA FUNDS MANAGEMENT LTD. in group SPHERA FUNDS MANAGEMENT LTD. More: the full row for SPHERA FUNDS MANAGEMENT LTD. 245,000 $4.13M 0.59% +60,000 13F-HR Timeline Group CHARLES SCHWAB INVESTMENT MANAGEMENT INC in group Charles Schwab Trust Co More: the full row for CHARLES SCHWAB INVESTMENT MANAGEMENT INC 224,602 $3.79M <0.01% new 13F-HR Timeline Group NORTHERN TRUST CORP in group NORTHERN TRUST CORP More: the full row for NORTHERN TRUST CORP 197,543 $3.33M <0.01% new 13F-HR Timeline Group CenterBook Partners LP More: the full row for CenterBook Partners LP 131,560 $2.22M 0.11% -135,253 13F-HR Timeline ALPS ADVISORS INC More: the full row for ALPS ADVISORS INC 129,406 $2.18M 0.01% new 13F-HR Timeline SEVEN GRAND MANAGERS, LLC More: the full row for SEVEN GRAND MANAGERS, LLC 125,000 $2.11M 0.08% 0 13F-HR Timeline BARCLAYS PLC in group BARCLAYS PLC More: the full row for BARCLAYS PLC 116,902 $1.97M <0.01% +46,008 13F-HR Timeline Group LMR Partners LLP in group LMR Partners LLP More: the full row for LMR Partners LLP 100,000 $1.69M 0.01% 0 13F-HR Timeline Group AMERIPRISE FINANCIAL INC in group AMERIPRISE FINANCIAL INC More: the full row for AMERIPRISE FINANCIAL INC 91,100 $1.54M <0.01% +3,765 13F-HR Timeline Group MANUFACTURERS LIFE INSURANCE COMPANY, T… in group MANUFACTURERS LIFE INSURANCE … More: the full row for MANUFACTURERS LIFE INSURANCE COMPANY, THE 84,803 $1.43M <0.01% +10,491 13F-HR Timeline Group Bank of New York Mellon Corp in group Bank of New York Mellon Corp More: the full row for Bank of New York Mellon Corp 57,326 $967K <0.01% new 13F-HR Timeline Group BANK OF AMERICA CORP /DE/ in group BANK OF AMERICA CORP /DE/ More: the full row for BANK OF AMERICA CORP /DE/ 55,430 $935K <0.01% +21,234 13F-HR Timeline Group TD Asset Management Inc More: the full row for TD Asset Management Inc 50,748 $856K <0.01% +7,882 13F-HR Timeline Nuveen, LLC in group TIAA More: the full row for Nuveen, LLC 44,470 $750K <0.01% new 13F-HR Timeline Group RENAISSANCE TECHNOLOGIES LLC More: the full row for RENAISSANCE TECHNOLOGIES LLC 39,685 $669K <0.01% new 13F-HR Timeline Sumitomo Mitsui Trust Group, Inc. in group Sumitomo Mitsui Trust Group, … More: the full row for Sumitomo Mitsui Trust Group, Inc. 38,665 $652K <0.01% -1,679 13F-HR Timeline Group Amova Asset Management Americas, Inc. in group Amova Asset Management Americ… More: the full row for Amova Asset Management Americas, Inc. 38,218 $644K 0.01% -2,126 13F-HR Timeline Group IQ EQ FUND MANAGEMENT (IRELAND) Ltd More: the full row for IQ EQ FUND MANAGEMENT (IRELAND) Ltd 37,226 $628K 0.04% +18,023 13F-HR Timeline Quadrature Capital Ltd in group Quadrature Capital Ltd More: the full row for Quadrature Capital Ltd 31,510 $532K <0.01% new 13F-HR Timeline Group Squarepoint Ops LLC in group Squarepoint Ops LLC More: the full row for Squarepoint Ops LLC 31,406 $530K <0.01% -5,797 13F-HR Timeline Group RHUMBLINE ADVISERS More: the full row for RHUMBLINE ADVISERS 30,648 $517K <0.01% new 13F-HR Timeline CITIGROUP INC in group CITIGROUP INC More: the full row for CITIGROUP INC 30,587 $516K <0.01% +28,343 13F-HR Timeline Group Virtus Investment Advisers, LLC in group Virtus Investment Advisers, L… More: the full row for Virtus Investment Advisers, LLC 26,430 $446K 0.1% new 13F-HR Timeline Group XTX Topco Ltd in group XTX Topco Ltd More: the full row for XTX Topco Ltd 24,956 $421K 0.01% new 13F-HR Timeline Group DEUTSCHE BANK AG\ in group DEUTSCHE BANK AG\ More: the full row for DEUTSCHE BANK AG\ 24,135 $407K <0.01% new 13F-HR Timeline Group WELLS FARGO & COMPANY/MN in group WELLS FARGO & COMPANY/MN More: the full row for WELLS FARGO & COMPANY/MN 23,302 $393K <0.01% +22,102 13F-HR Timeline Group ALLIANCEBERNSTEIN L.P. More: the full row for ALLIANCEBERNSTEIN L.P. 22,650 $382K <0.01% new 13F-HR Timeline MILLENNIUM MANAGEMENT LLC in group MILLENNIUM MANAGEMENT LLC More: the full row for MILLENNIUM MANAGEMENT LLC 21,926 $370K <0.01% -354,967 13F-HR Timeline Group TWO SIGMA INVESTMENTS, LP in group TWO SIGMA INVESTMENTS, LP More: the full row for TWO SIGMA INVESTMENTS, LP 18,374 $310K <0.01% new 13F-HR Timeline Group Magnus Financial Group LLC More: the full row for Magnus Financial Group LLC 15,600 $263K 0.02% new 13F-HR Timeline MetLife Investment Management, LLC in group MetLife Investment Management… More: the full row for MetLife Investment Management, LLC 14,841 $250K <0.01% new 13F-HR Timeline Group Invesco Ltd. in group Invesco Ltd. More: the full row for Invesco Ltd. 13,087 $221K <0.01% new 13F-HR Timeline Group AXQ CAPITAL, LP More: the full row for AXQ CAPITAL, LP 12,946 $218K 0.02% new 13F-HR Timeline SEI INVESTMENTS CO in group SEI INVESTMENTS CO More: the full row for SEI INVESTMENTS CO 12,088 $204K <0.01% new 13F-HR Timeline Group SUSQUEHANNA INTERNATIONAL GROUP, LLP in group SUSQUEHANNA INTERNATIONAL GRO… More: the full row for SUSQUEHANNA INTERNATIONAL GROUP, LLP 11,622 $196K <0.01% new 13F-HR Timeline Group MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. in group Mirae Asset Global Investment… More: the full row for MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 11,193 $189K <0.01% new 13F-HR Timeline Group Parallel Advisors, LLC More: the full row for Parallel Advisors, LLC 11,191 $189K <0.01% +5,641 13F-HR Timeline GOLDMAN SACHS GROUP INC in group GOLDMAN SACHS GROUP INC More: the full row for GOLDMAN SACHS GROUP INC 11,183 $189K <0.01% -159,512 13F-HR Timeline Group SG Americas Securities, LLC More: the full row for SG Americas Securities, LLC 9,277 $157K <0.01% new 13F-HR Timeline NEW YORK STATE COMMON RETIREMENT FUND More: the full row for NEW YORK STATE COMMON RETIREMENT FUND 8,600 $145K <0.01% new 13F-HR Timeline Police & Firemen's Retirement System of… More: the full row for Police & Firemen's Retirement System of New Jersey 7,200 $121K <0.01% new 13F-HR Timeline FEDERATED HERMES, INC. in group FEDERATED HERMES, INC. More: the full row for FEDERATED HERMES, INC. 5,000 $84.3K <0.01% -25,000 13F-HR Timeline Group ALBION FINANCIAL GROUP /UT More: the full row for ALBION FINANCIAL GROUP /UT 4,854 $81.9K <0.01% 0 13F-HR Timeline STRS OHIO More: the full row for STRS OHIO 4,800 $81K <0.01% new 13F-HR Timeline BNP PARIBAS FINANCIAL MARKETS in group BNP PARIBAS FINANCIAL MARKETS More: the full row for BNP PARIBAS FINANCIAL MARKETS 3,800 $64.1K <0.01% new 13F-HR Timeline Group Legal & General Group Plc in group Legal & General Group Plc More: the full row for Legal & General Group Plc 2,374 $40K <0.01% new 13F-HR Timeline Group Ameritas Investment Partners, Inc. in group Ameritas Investment Partners,… More: the full row for Ameritas Investment Partners, Inc. 2,215 $37.4K <0.01% new 13F-HR Timeline Group Russell Investments Group, Ltd. in group Russell Investments Group, Lt… More: the full row for Russell Investments Group, Ltd. 1,952 $32.9K <0.01% new 13F-HR Timeline Group State of Wyoming More: the full row for State of Wyoming 1,407 $23.7K <0.01% new 13F-HR Timeline STANCE CAPITAL LLC More: the full row for STANCE CAPITAL LLC 1,384 $23.3K 0.01% new 13F-HR Timeline ROYAL BANK OF CANADA in group ROYAL BANK OF CANADA More: the full row for ROYAL BANK OF CANADA 1,381 $23K <0.01% +1,150 13F-HR Timeline Group Tower Research Capital LLC (TRC) in group Tower Research Capital LLC (T… More: the full row for Tower Research Capital LLC (TRC) 1,014 $17.1K <0.01% +1,013 13F-HR Timeline Group TD Waterhouse Canada Inc. More: the full row for TD Waterhouse Canada Inc. 573 $9.46K <0.01% new 13F-HR Timeline Benson Wealth Management INC More: the full row for Benson Wealth Management INC 363 $6.12K 0.01% new 13F-HR Timeline CALIFORNIA STATE TEACHERS RETIREMENT SY… More: the full row for CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 336 $5.67K <0.01% new 13F-HR/A Timeline Sterling Capital Management LLC More: the full row for Sterling Capital Management LLC 212 $3.58K <0.01% new 13F-HR Timeline JONES FINANCIAL COMPANIES LLLP in group JONES FINANCIAL COMPANIES LLLP More: the full row for JONES FINANCIAL COMPANIES LLLP 200 $3.29K <0.01% new 13F-HR Timeline Group Avion Wealth More: the full row for Avion Wealth 200 $3K <0.01% +100 13F-HR Timeline HOLLENCREST CAPITAL MANAGEMENT More: the full row for HOLLENCREST CAPITAL MANAGEMENT 5 $84 <0.01% new 13F-HR Timeline Caitong International Asset Management … More: the full row for Caitong International Asset Management Co., Ltd 1 $17 <0.01% new 13F-HR Timeline