FMR LLC in group FMR LLC More: the full row for FMR LLC 10,025,017 $509M 0.02% +3,195,771 13F-HR Timeline Group ORBIMED ADVISORS LLC in group ORBIMED ADVISORS LLC More: the full row for ORBIMED ADVISORS LLC 6,776,632 $344M 6.51% -1,182,906 13F-HR Timeline Group Polar Capital Holdings Plc in group Polar Capital Holdings Plc More: the full row for Polar Capital Holdings Plc 6,430,636 $326M 0.92% +1,364,703 13F-HR Timeline Group BlackRock, Inc. in group BlackRock, Inc. More: the full row for BlackRock, Inc. 4,359,704 $221M <0.01% +674,997 13F-HR Timeline Group Vestal Point Capital, LP More: the full row for Vestal Point Capital, LP 4,000,000 $203M 4.74% +750,000 13F-HR Timeline VANGUARD GROUP INC group of 6 filers holding More: the full row for VANGUARD GROUP INC 3,588,112 $182M +728,269 Timeline VANGUARD CAPITAL MANAGEMENT LLC : 2,569,002 (<0.01%) 13F-HR VANGUARD PORTFOLIO MANAGEMENT LLC : 562,763 (<0.01%) 13F-HR VANGUARD FIDUCIARY TRUST CO : 383,490 (<0.01%) 13F-HR VANGUARD ASSET MANAGEMENT, Ltd : 33,432 (<0.01%) 13F-HR Vanguard Global Advisers, LLC : 26,833 (<0.01%) 13F-HR Vanguard Investments Australia, L… : 12,592 (<0.01%) 13F-HR Commodore Capital LP in group Commodore Capital LP More: the full row for Commodore Capital LP 3,275,000 $166M 9.9% 0 13F-HR Timeline Group PRICE T ROWE ASSOCIATES INC /MD/ More: the full row for PRICE T ROWE ASSOCIATES INC /MD/ 2,903,907 $147M 0.01% +2,806,160 13F-HR Timeline CITADEL ADVISORS LLC in group CITADEL ADVISORS LLC More: the full row for CITADEL ADVISORS LLC 2,068,992 $105M 0.06% +325,077 13F-HR Timeline Group Fairmount Funds Management LLC More: the full row for Fairmount Funds Management LLC 1,855,644 $94.2M 6.22% 0 13F-HR Timeline Siren, L.L.C. in group Siren, L.L.C. More: the full row for Siren, L.L.C. 1,774,411 $90.1M 1.83% +1,028,185 13F-HR Timeline Group Bellevue Group AG in group Bellevue Group AG More: the full row for Bellevue Group AG 1,490,000 $75.6M 1.59% -830,867 13F-HR Timeline Group GEODE CAPITAL MANAGEMENT, LLC in group GEODE CAPITAL MANAGEMENT, LLC More: the full row for GEODE CAPITAL MANAGEMENT, LLC 1,407,202 $71.4M <0.01% +340,782 13F-HR Timeline Group First Light Asset Management, LLC More: the full row for First Light Asset Management, LLC 1,360,750 $69.1M 4.2% +1,158,883 13F-HR Timeline STATE STREET CORP in group STATE STREET CORP More: the full row for STATE STREET CORP 1,213,616 $61.6M <0.01% +122,510 13F-HR Timeline Group Pictet Asset Management Holding SA in group Pictet Asset Management Holdi… More: the full row for Pictet Asset Management Holding SA 1,161,784 $59M 0.06% +232,240 13F-HR Timeline Group ADAGE CAPITAL PARTNERS GP, L.L.C. in group ADAGE CAPITAL PARTNERS GP, L.… More: the full row for ADAGE CAPITAL PARTNERS GP, L.L.C. 1,083,313 $55M 0.08% new 13F-HR Timeline Group NOVO HOLDINGS A/S More: the full row for NOVO HOLDINGS A/S 1,000,000 $50.8M 2.95% -280,000 13F-HR Timeline First Turn Management, LLC More: the full row for First Turn Management, LLC 954,360 $48.4M 5.18% +330,521 13F-HR Timeline SAMLYN CAPITAL, LLC in group SAMLYN CAPITAL, LLC More: the full row for SAMLYN CAPITAL, LLC 912,637 $46.3M 0.77% new 13F-HR Timeline Group BAKER BROS. ADVISORS LP in group BAKER BROS. ADVISORS LP More: the full row for BAKER BROS. ADVISORS LP 905,191 $45.9M 0.23% 0 13F-HR Timeline Group Candriam S.C.A. More: the full row for Candriam S.C.A. 905,674 $45.9M 0.21% +311,595 13F-HR Timeline Tri Locum Partners LP More: the full row for Tri Locum Partners LP 866,716 $44M 5.41% new 13F-HR Timeline ALLIANCEBERNSTEIN L.P. More: the full row for ALLIANCEBERNSTEIN L.P. 896,161 $35.1M 0.01% +124,276 13F-HR Timeline DIMENSIONAL FUND ADVISORS LP in group DIMENSIONAL FUND ADVISORS LP More: the full row for DIMENSIONAL FUND ADVISORS LP 671,412 $34.1M 0.01% -10,303 13F-HR Timeline Group Balyasny Asset Management L.P. in group Balyasny Asset Management More: the full row for Balyasny Asset Management L.P. 607,189 $30.8M 0.06% +297,164 13F-HR Timeline Group Jupiter Topco LLC in group Janus Henderson More: the full row for Jupiter Topco LLC 604,122 $30.6M 0.01% 13F-HR Timeline Group AMERICAN CENTURY COMPANIES INC in group AMERICAN CENTURY COMPANIES INC More: the full row for AMERICAN CENTURY COMPANIES INC 566,165 $28.7M 0.01% +504,049 13F-HR Timeline Group Avidity Partners Management LP More: the full row for Avidity Partners Management LP 550,000 $27.9M 4.47% +150,000 13F-HR Timeline MARSHALL WACE, LLP in group MARSHALL WACE, LLP More: the full row for MARSHALL WACE, LLP 532,269 $27M 0.02% new 13F-HR Timeline Group Venrock Adviser, LLC More: the full row for Venrock Adviser, LLC 526,331 $26.7M 0.81% -1,200,000 13F-HR Timeline MORGAN STANLEY in group MORGAN STANLEY More: the full row for MORGAN STANLEY 509,928 $25.9M <0.01% -8,644 13F-HR Timeline Group Affinity Asset Advisors, LLC More: the full row for Affinity Asset Advisors, LLC 500,000 $25.4M 1.24% -86,904 13F-HR Timeline SILVERARC CAPITAL MANAGEMENT, LLC in group SILVERARC CAPITAL MANAGEMENT,… More: the full row for SILVERARC CAPITAL MANAGEMENT, LLC 489,382 $24.8M 2.76% new 13F-HR Timeline Group Logos Global Management LP More: the full row for Logos Global Management LP 465,000 $23.6M 1.02% -75,000 13F-HR Timeline Rock Springs Capital Management LP More: the full row for Rock Springs Capital Management LP 464,625 $23.6M 1.15% -361,875 13F-HR Timeline NORTHERN TRUST CORP in group NORTHERN TRUST CORP More: the full row for NORTHERN TRUST CORP 440,938 $22.4M <0.01% +68,622 13F-HR Timeline Group CHARLES SCHWAB INVESTMENT MANAGEMENT INC in group Charles Schwab Trust Co More: the full row for CHARLES SCHWAB INVESTMENT MANAGEMENT INC 424,440 $21.5M <0.01% +63,863 13F-HR Timeline Group UBS Group AG group of 2 filers holding More: the full row for UBS Group AG 422,187 $21.4M +71,168 Timeline MILLENNIUM MANAGEMENT LLC in group MILLENNIUM MANAGEMENT LLC More: the full row for MILLENNIUM MANAGEMENT LLC 411,362 $20.9M 0.01% +66,044 13F-HR Timeline Group Nicholas Investment Partners, LP More: the full row for Nicholas Investment Partners, LP 391,529 $19.9M 1.12% +208,801 13F-HR Timeline ADAR1 Capital Management, LLC in group ADAR1 Capital Management, LLC More: the full row for ADAR1 Capital Management, LLC 387,718 $19.7M 0.92% +58,178 13F-HR Timeline Group Nuveen, LLC in group TIAA More: the full row for Nuveen, LLC 374,217 $19M <0.01% +268,334 13F-HR Timeline Group Seven Fleet Capital Management LP More: the full row for Seven Fleet Capital Management LP 365,386 $18.5M 3.06% +201,356 13F-HR Timeline Woodline Partners LP More: the full row for Woodline Partners LP 347,142 $17.6M 0.05% +45,469 13F-HR Timeline STEMPOINT CAPITAL LP More: the full row for STEMPOINT CAPITAL LP 346,914 $17.6M 3.05% -16,524 13F-HR Timeline LORD, ABBETT & CO. LLC More: the full row for LORD, ABBETT & CO. LLC 330,759 $16.8M 0.05% new 13F-HR Timeline Spruce Street Capital LP More: the full row for Spruce Street Capital LP 329,006 $16.7M 3.28% 0 13F-HR Timeline GOLDMAN SACHS GROUP INC in group GOLDMAN SACHS GROUP INC More: the full row for GOLDMAN SACHS GROUP INC 322,156 $16.3M <0.01% -150,959 13F-HR Timeline Group Longaeva Partners L.P. More: the full row for Longaeva Partners L.P. 312,560 $15.9M 0.46% +199,495 13F-HR Timeline JENNISON ASSOCIATES LLC More: the full row for JENNISON ASSOCIATES LLC 309,219 $15.7M 0.01% +39 13F-HR Timeline Assenagon Asset Management S.A. More: the full row for Assenagon Asset Management S.A. 306,574 $15.6M 0.02% new 13F-HR/A Timeline D. E. Shaw & Co., Inc. in group D. E. Shaw & Co., Inc. More: the full row for D. E. Shaw & Co., Inc. 305,703 $15.5M 0.01% +112,172 13F-HR Timeline Group T. Rowe Price Investment Management, In… More: the full row for T. Rowe Price Investment Management, Inc. 300,891 $15.3M 0.01% new 13F-HR Timeline TimesSquare Capital Management, LLC More: the full row for TimesSquare Capital Management, LLC 261,344 $13.3M 0.2% +216,344 13F-HR Timeline AMERIPRISE FINANCIAL INC in group AMERIPRISE FINANCIAL INC More: the full row for AMERIPRISE FINANCIAL INC 251,192 $12.7M <0.01% +90,615 13F-HR Timeline Group Deep Track Capital, LP More: the full row for Deep Track Capital, LP 225,000 $11.4M 0.17% new 13F-HR Timeline Blackstone Inc. in group Blackstone Inc. More: the full row for Blackstone Inc. 215,744 $10.9M 0.04% new 13F-HR Timeline Group The filing omitted confidential holdings, a later amendment may add them. NEUBERGER BERMAN GROUP LLC in group NEUBERGER BERMAN GROUP LLC More: the full row for NEUBERGER BERMAN GROUP LLC 214,343 $10.9M 0.01% +152,711 13F-HR Timeline Group Patient Square Capital LP More: the full row for Patient Square Capital LP 212,500 $10.8M 1.67% +12,500 13F-HR Timeline Soleus Capital Management, L.P. More: the full row for Soleus Capital Management, L.P. 165,677 $8.41M 0.29% -65,192 13F-HR Timeline Connor, Clark & Lunn Investment Managem… More: the full row for Connor, Clark & Lunn Investment Management Ltd. 160,879 $8.16M 0.02% -30,414 13F-HR Timeline Squadron Capital Management LLC More: the full row for Squadron Capital Management LLC 160,000 $8.12M 2.78% new 13F-HR Timeline Cormorant Asset Management, LP More: the full row for Cormorant Asset Management, LP 150,000 $7.61M 0.39% new 13F-HR Timeline Integral Health Asset Management, LLC More: the full row for Integral Health Asset Management, LLC 150,000 $7.61M 0.31% new 13F-HR Timeline HighVista Strategies LLC More: the full row for HighVista Strategies LLC 137,866 $7M 1.6% +64,764 13F-HR Timeline Eversept Partners, LP More: the full row for Eversept Partners, LP 136,631 $6.93M 0.38% new 13F-HR Timeline WELLINGTON MANAGEMENT GROUP LLP in group WELLINGTON MANAGEMENT GROUP L… More: the full row for WELLINGTON MANAGEMENT GROUP LLP 133,143 $6.76M <0.01% -16,983 13F-HR Timeline Group Ikarian Capital, LLC More: the full row for Ikarian Capital, LLC 126,541 $6.42M 1.05% new 13F-HR Timeline Bank of New York Mellon Corp in group Bank of New York Mellon Corp More: the full row for Bank of New York Mellon Corp 118,853 $6.03M <0.01% -1,204 13F-HR Timeline Group Invesco Ltd. in group Invesco Ltd. More: the full row for Invesco Ltd. 112,972 $5.73M <0.01% +51,220 13F-HR Timeline Group SPHERA FUNDS MANAGEMENT LTD. in group SPHERA FUNDS MANAGEMENT LTD. More: the full row for SPHERA FUNDS MANAGEMENT LTD. 112,765 $5.72M 0.82% -40,500 13F-HR Timeline Group J. Goldman & Co LP More: the full row for J. Goldman & Co LP 112,129 $5.69M 0.2% +83,467 13F-HR Timeline TD Asset Management Inc More: the full row for TD Asset Management Inc 109,738 $5.57M <0.01% +101,138 13F-HR Timeline Cinctive Capital Management LP More: the full row for Cinctive Capital Management LP 107,688 $5.47M 0.22% -5,654 13F-HR Timeline Exome Asset Management LLC More: the full row for Exome Asset Management LLC 100,203 $5.09M 3.14% -119,888 13F-HR Timeline BANK OF AMERICA CORP /DE/ in group BANK OF AMERICA CORP /DE/ More: the full row for BANK OF AMERICA CORP /DE/ 98,023 $4.97M <0.01% +52,861 13F-HR Timeline Group Swiss National Bank More: the full row for Swiss National Bank 94,573 $4.8M <0.01% +30,300 13F-HR Timeline Russell Investments Group, Ltd. in group Russell Investments Group, Lt… More: the full row for Russell Investments Group, Ltd. 91,938 $4.67M <0.01% +88,937 13F-HR Timeline Group DV EQUITIES, LLC More: the full row for DV EQUITIES, LLC 76,250 $3.87M 0.56% 13F-HR Timeline MANUFACTURERS LIFE INSURANCE COMPANY, T… in group MANUFACTURERS LIFE INSURANCE … More: the full row for MANUFACTURERS LIFE INSURANCE COMPANY, THE 75,265 $3.82M <0.01% +51,824 13F-HR Timeline Group VOYA INVESTMENT MANAGEMENT LLC in group VOYA INVESTMENT MANAGEMENT LLC More: the full row for VOYA INVESTMENT MANAGEMENT LLC 74,453 $3.78M <0.01% +59,962 13F-HR Timeline Group Artia Global Partners LP More: the full row for Artia Global Partners LP 72,100 $3.66M 0.7% +51,200 13F-HR Timeline ALGERT GLOBAL LLC More: the full row for ALGERT GLOBAL LLC 72,090 $3.66M 0.04% new 13F-HR Timeline Informed Momentum Co LLC More: the full row for Informed Momentum Co LLC 70,432 $3.57M 0.32% -12,362 13F-HR Timeline GREAT POINT PARTNERS LLC More: the full row for GREAT POINT PARTNERS LLC 70,000 $3.55M 0.84% new 13F-HR Timeline SEVEN GRAND MANAGERS, LLC More: the full row for SEVEN GRAND MANAGERS, LLC 70,000 $3.55M 0.14% new 13F-HR Timeline NEW YORK STATE COMMON RETIREMENT FUND More: the full row for NEW YORK STATE COMMON RETIREMENT FUND 67,151 $3.41M <0.01% +28,503 13F-HR Timeline Legato Capital Management LLC More: the full row for Legato Capital Management LLC 64,769 $3.29M 0.27% +33,595 13F-HR Timeline Tidal Investments LLC in group Tidal Investments LLC More: the full row for Tidal Investments LLC 60,694 $3.08M 0.01% +13,179 13F-HR Timeline Group Tema ETFs LLC More: the full row for Tema ETFs LLC 60,694 $3.08M 0.1% +17,638 13F-HR Timeline RHUMBLINE ADVISERS More: the full row for RHUMBLINE ADVISERS 57,241 $2.9M <0.01% +7,053 13F-HR Timeline Schonfeld Strategic Advisors LLC More: the full row for Schonfeld Strategic Advisors LLC 55,884 $2.84M 0.01% -162,983 13F-HR Timeline CALIFORNIA STATE TEACHERS RETIREMENT SY… More: the full row for CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 53,315 $2.71M <0.01% +21,401 13F-HR/A Timeline Atom Investors LP More: the full row for Atom Investors LP 50,122 $2.54M 0.23% new 13F-HR Timeline Jones Hill Capital LP More: the full row for Jones Hill Capital LP 49,850 $2.53M 0.54% -543,190 13F-HR Timeline BNP PARIBAS FINANCIAL MARKETS in group BNP PARIBAS FINANCIAL MARKETS More: the full row for BNP PARIBAS FINANCIAL MARKETS 45,685 $2.32M <0.01% +36,058 13F-HR Timeline Group DEUTSCHE BANK AG\ in group DEUTSCHE BANK AG\ More: the full row for DEUTSCHE BANK AG\ 45,109 $2.29M <0.01% +9,790 13F-HR Timeline Group JPMORGAN CHASE & CO in group JPMORGAN CHASE & CO More: the full row for JPMORGAN CHASE & CO 37,890 $2.06M <0.01% +17,070 13F-HR Timeline Group TUDOR INVESTMENT CORP ET AL More: the full row for TUDOR INVESTMENT CORP ET AL 40,118 $2.04M 0.01% new 13F-HR Timeline WELLS FARGO & COMPANY/MN in group WELLS FARGO & COMPANY/MN More: the full row for WELLS FARGO & COMPANY/MN 39,079 $1.98M <0.01% +24,788 13F-HR Timeline Group BOOTHBAY FUND MANAGEMENT, LLC More: the full row for BOOTHBAY FUND MANAGEMENT, LLC 39,031 $1.98M 0.04% new 13F-HR Timeline Trexquant Investment LP More: the full row for Trexquant Investment LP 37,491 $1.9M 0.01% -40,757 13F-HR Timeline Legal & General Group Plc in group Legal & General Group Plc More: the full row for Legal & General Group Plc 32,924 $1.67M <0.01% -159 13F-HR Timeline Group Ishara Investments LP More: the full row for Ishara Investments LP 32,800 $1.66M 1.22% new 13F-HR Timeline Brevan Howard Capital Management LP in group Brevan Howard Capital Managem… More: the full row for Brevan Howard Capital Management LP 32,718 $1.66M 0.02% +10,486 13F-HR Timeline Group FRANKLIN RESOURCES INC in group Franklin Resources More: the full row for FRANKLIN RESOURCES INC 31,163 $1.58M <0.01% +10,981 13F-HR Timeline Group CITIGROUP INC in group CITIGROUP INC More: the full row for CITIGROUP INC 30,712 $1.56M <0.01% +16,011 13F-HR Timeline Group Engineers Gate Manager LP More: the full row for Engineers Gate Manager LP 29,152 $1.48M 0.02% new 13F-HR Timeline STATE OF WISCONSIN INVESTMENT BOARD More: the full row for STATE OF WISCONSIN INVESTMENT BOARD 26,110 $1.33M <0.01% -2,305 13F-HR Timeline Erste Asset Management GmbH in group Erste Asset Management GmbH More: the full row for Erste Asset Management GmbH 25,000 $1.27M 0.01% new 13F-HR Timeline Group MetLife Investment Management, LLC in group MetLife Investment Management… More: the full row for MetLife Investment Management, LLC 24,972 $1.27M 0.01% +2,878 13F-HR Timeline Group TWO SIGMA INVESTMENTS, LP in group TWO SIGMA INVESTMENTS, LP More: the full row for TWO SIGMA INVESTMENTS, LP 22,758 $1.15M <0.01% new 13F-HR Timeline Group Mirae Asset Global Investments Co., Ltd. group of 2 filers holding More: the full row for Mirae Asset Global Investments Co., Ltd. 22,453 $1.14M +908 Timeline BARCLAYS PLC in group BARCLAYS PLC More: the full row for BARCLAYS PLC 20,816 $1.06M <0.01% +8,986 13F-HR Timeline Group Lighthouse Investment Partners, LLC in group Lighthouse Investment Partner… More: the full row for Lighthouse Investment Partners, LLC 20,000 $1.01M 0.03% -55,000 13F-HR Timeline Group Creative Planning in group Creative Planning More: the full row for Creative Planning 19,386 $984K <0.01% +5,714 13F-HR Timeline Group Hudson Bay Capital Management LP in group Hudson Bay Capital Management… More: the full row for Hudson Bay Capital Management LP 19,000 $964K <0.01% new 13F-HR Timeline Group SUSQUEHANNA INTERNATIONAL GROUP, LLP group of 2 filers holding More: the full row for SUSQUEHANNA INTERNATIONAL GROUP, LLP 18,455 $937K -55,778 Timeline PRUDENTIAL FINANCIAL INC in group PRUDENTIAL FINANCIAL INC More: the full row for PRUDENTIAL FINANCIAL INC 17,580 $892K <0.01% -49,360 13F-HR Timeline Group Handelsbanken Fonder AB More: the full row for Handelsbanken Fonder AB 17,300 $878K <0.01% new 13F-HR Timeline Verdad Advisers, LP More: the full row for Verdad Advisers, LP 16,957 $861K 0.82% new 13F-HR Timeline Penserra Capital Management LLC in group Penserra Capital Management L… More: the full row for Penserra Capital Management LLC 16,660 $845K 0.01% new 13F-HR Timeline Group CANADA PENSION PLAN INVESTMENT BOARD More: the full row for CANADA PENSION PLAN INVESTMENT BOARD 15,400 $782K <0.01% +100 13F-HR Timeline OPTIMIZE FINANCIAL INC. More: the full row for OPTIMIZE FINANCIAL INC. 15,003 $761K 0.27% -52 13F-HR Timeline Sound Capital Solutions LLC More: the full row for Sound Capital Solutions LLC 15,003 $761K 0.18% 13F-HR Timeline ARIZONA STATE RETIREMENT SYSTEM More: the full row for ARIZONA STATE RETIREMENT SYSTEM 13,007 $660K <0.01% +4,042 13F-HR Timeline Police & Firemen's Retirement System of… More: the full row for Police & Firemen's Retirement System of New Jersey 12,635 $641K <0.01% +1,473 13F-HR Timeline KLP KAPITALFORVALTNING AS More: the full row for KLP KAPITALFORVALTNING AS 12,300 $624K <0.01% +5,500 13F-HR Timeline Bridgefront Capital, LLC More: the full row for Bridgefront Capital, LLC 12,096 $614K 0.16% +6,291 13F-HR Timeline INTECH INVESTMENT MANAGEMENT LLC More: the full row for INTECH INVESTMENT MANAGEMENT LLC 12,090 $614K 0.01% +1,482 13F-HR Timeline Zurcher Kantonalbank (Zurich Cantonalba… More: the full row for Zurcher Kantonalbank (Zurich Cantonalbank) 10,933 $555K <0.01% 0 13F-HR Timeline State of New Jersey Common Pension Fund… in group State of New Jersey Common Pe… More: the full row for State of New Jersey Common Pension Fund D 10,829 $550K <0.01% -326 13F-HR Timeline Group SG Americas Securities, LLC More: the full row for SG Americas Securities, LLC 10,751 $546K <0.01% new 13F-HR Timeline CAPSTONE INVESTMENT ADVISORS, LLC in group CAPSTONE INVESTMENT ADVISORS,… More: the full row for CAPSTONE INVESTMENT ADVISORS, LLC 10,577 $537K <0.01% new 13F-HR Timeline Group STATE BOARD OF ADMINISTRATION OF FLORID… More: the full row for STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM 10,480 $532K <0.01% 0 13F-HR Timeline OSAIC HOLDINGS, INC. in group OSAIC HOLDINGS, INC. More: the full row for OSAIC HOLDINGS, INC. 10,397 $528K <0.01% +365 13F-HR Timeline Group AXQ CAPITAL, LP More: the full row for AXQ CAPITAL, LP 10,095 $512K 0.06% -537 13F-HR Timeline DIADEMA PARTNERS LP More: the full row for DIADEMA PARTNERS LP 10,000 $508K 0.18% +9,755 13F-HR Timeline XTX Topco Ltd in group XTX Topco Ltd More: the full row for XTX Topco Ltd 9,957 $505K 0.01% -28,366 13F-HR Timeline Group China Universal Asset Management Co., L… More: the full row for China Universal Asset Management Co., Ltd. 9,693 $492K 0.03% -839 13F-HR Timeline LETKO, BROSSEAU & ASSOCIATES INC More: the full row for LETKO, BROSSEAU & ASSOCIATES INC 9,600 $487K 0.01% 0 13F-HR Timeline Persistent Asset Partners Ltd More: the full row for Persistent Asset Partners Ltd 9,433 $479K 0.15% +2,827 13F-HR Timeline ROYAL BANK OF CANADA in group ROYAL BANK OF CANADA More: the full row for ROYAL BANK OF CANADA 9,378 $476K <0.01% +3,954 13F-HR Timeline Group Quantinno Capital Management LP More: the full row for Quantinno Capital Management LP 8,636 $438K <0.01% +2,098 13F-HR Timeline Aquatic Capital Management LLC More: the full row for Aquatic Capital Management LLC 8,400 $426K 0.01% new 13F-HR Timeline PROFUND ADVISORS LLC More: the full row for PROFUND ADVISORS LLC 7,726 $392K 0.01% -525 13F-HR Timeline ProShare Advisors LLC More: the full row for ProShare Advisors LLC 7,606 $386K <0.01% -753 13F-HR Timeline BAMCO INC /NY/ in group Baron Capital More: the full row for BAMCO INC /NY/ 7,500 $381K <0.01% new 13F-HR Timeline Group Virtus Investment Advisers, LLC in group Virtus Investment Advisers, L… More: the full row for Virtus Investment Advisers, LLC 7,093 $360K 0.08% -9,080 13F-HR Timeline Group PSP Research LLC More: the full row for PSP Research LLC 7,000 $355K 0.19% 0 13F-HR Timeline FOX RUN MANAGEMENT, L.L.C. More: the full row for FOX RUN MANAGEMENT, L.L.C. 6,709 $340K 0.06% -8,864 13F-HR Timeline Knott David M Jr More: the full row for Knott David M Jr 6,183 $314K 0.17% new 13F-HR Timeline Amundi in group Amundi More: the full row for Amundi 6,041 $307K <0.01% -895 13F-HR Timeline Group CenterBook Partners LP More: the full row for CenterBook Partners LP 5,651 $287K 0.01% new 13F-HR Timeline STRS OHIO More: the full row for STRS OHIO 5,600 $284K <0.01% new 13F-HR Timeline VICTORY CAPITAL MANAGEMENT INC More: the full row for VICTORY CAPITAL MANAGEMENT INC 5,427 $275K <0.01% new 13F-HR Timeline Rafferty Asset Management, LLC More: the full row for Rafferty Asset Management, LLC 5,368 $272K <0.01% new 13F-HR Timeline STIFEL FINANCIAL CORP in group STIFEL FINANCIAL CORP More: the full row for STIFEL FINANCIAL CORP 5,183 $263K <0.01% -2,741 13F-HR Timeline Group SEI INVESTMENTS CO in group SEI INVESTMENTS CO More: the full row for SEI INVESTMENTS CO 5,171 $262K <0.01% new 13F-HR Timeline Group Squarepoint Ops LLC in group Squarepoint Ops LLC More: the full row for Squarepoint Ops LLC 5,099 $259K <0.01% new 13F-HR Timeline Group Arrowpoint Investment Partners (Singapo… in group Arrowpoint Investment Partner… More: the full row for Arrowpoint Investment Partners (Singapore) Pte. Ltd. 4,499 $228K 0.07% new 13F-HR Timeline Group WINTON GROUP Ltd in group WINTON GROUP Ltd More: the full row for WINTON GROUP Ltd 4,495 $228K 0.01% new 13F-HR Timeline Group XPONANCE LLC More: the full row for XPONANCE LLC 4,225 $214K <0.01% new 13F-HR Timeline Quarry LP More: the full row for Quarry LP 4,033 $205K 0.03% new 13F-HR Timeline Ameritas Investment Partners, Inc. in group Ameritas Investment Partners,… More: the full row for Ameritas Investment Partners, Inc. 3,888 $197K 0.01% +439 13F-HR Timeline Group FNY Investment Advisers, LLC More: the full row for FNY Investment Advisers, LLC 2,500 $126K 0.05% new 13F-HR Timeline State of Wyoming More: the full row for State of Wyoming 1,884 $95.6K 0.01% new 13F-HR Timeline KBC Group NV in group KBC Group NV More: the full row for KBC Group NV 1,805 $92K <0.01% +847 13F-HR Timeline Group Versant Capital Management, Inc More: the full row for Versant Capital Management, Inc 1,581 $80.2K 0.01% +6 13F-HR Timeline Tower Research Capital LLC (TRC) in group Tower Research Capital LLC (T… More: the full row for Tower Research Capital LLC (TRC) 1,491 $75.7K <0.01% -1,980 13F-HR Timeline Group GF FUND MANAGEMENT CO. LTD. More: the full row for GF FUND MANAGEMENT CO. LTD. 1,258 $63.8K <0.01% -75 13F-HR Timeline NISA INVESTMENT ADVISORS, LLC More: the full row for NISA INVESTMENT ADVISORS, LLC 1,209 $61.4K <0.01% +165 13F-HR Timeline Caitong International Asset Management … More: the full row for Caitong International Asset Management Co., Ltd 980 $49.7K 0.01% new 13F-HR Timeline Farther Finance Advisors, LLC More: the full row for Farther Finance Advisors, LLC 784 $39.9K <0.01% -26 13F-HR Timeline US BANCORP \DE\ in group US BANCORP \DE\ More: the full row for US BANCORP \DE\ 737 $37.4K <0.01% +570 13F-HR Timeline Group BNP PARIBAS ASSET MANAGEMENT Holding S.… in group BNP PARIBAS ASSET MANAGEMENT … More: the full row for BNP PARIBAS ASSET MANAGEMENT Holding S.A. 626 $31.8K <0.01% -218 13F-HR Timeline Group Kemnay Advisory Services Inc. More: the full row for Kemnay Advisory Services Inc. 566 $28.7K <0.01% new 13F-HR Timeline SIMPLEX TRADING, LLC More: the full row for SIMPLEX TRADING, LLC 456 $23.1K <0.01% -7,427 13F-HR Timeline SIGNATUREFD, LLC More: the full row for SIGNATUREFD, LLC 336 $17.1K <0.01% +100 13F-HR Timeline Arax Advisory Partners More: the full row for Arax Advisory Partners 331 $16.8K <0.01% new 13F-HR Timeline J.Safra Asset Management Corp More: the full row for J.Safra Asset Management Corp 300 $15.2K <0.01% new 13F-HR Timeline Nykredit A/S in group Nykredit A/S More: the full row for Nykredit A/S 259 $13.1K <0.01% 13F-HR Timeline Group GAMMA Investing LLC More: the full row for GAMMA Investing LLC 228 $11.6K <0.01% +6 13F-HR Timeline Optiver Holding B.V. in group Optiver Holding B.V. More: the full row for Optiver Holding B.V. 219 $11.1K <0.01% new 13F-HR Timeline Group MassMutual Private Wealth & Trust, FSB More: the full row for MassMutual Private Wealth & Trust, FSB 208 $10.6K <0.01% 0 13F-HR Timeline SMA Capital LLC More: the full row for SMA Capital LLC 204 $10.4K <0.01% new 13F-HR Timeline Sterling Capital Management LLC More: the full row for Sterling Capital Management LLC 150 $7.61K <0.01% -106 13F-HR Timeline Integrated Wealth Concepts LLC More: the full row for Integrated Wealth Concepts LLC 64 $3.25K <0.01% new 13F-HR Timeline Larson Financial Group LLC More: the full row for Larson Financial Group LLC 61 $3.1K <0.01% 0 13F-HR Timeline Cornerstone Financial Management LLC More: the full row for Cornerstone Financial Management LLC 42 $2.13K <0.01% 0 13F-HR/A Timeline ROTHSCHILD INVESTMENT LLC More: the full row for ROTHSCHILD INVESTMENT LLC 41 $2.08K <0.01% +1 13F-HR Timeline GROUP ONE TRADING LLC More: the full row for GROUP ONE TRADING LLC 35 $1.78K <0.01% new 13F-HR Timeline SBI Securities Co., Ltd. More: the full row for SBI Securities Co., Ltd. 32 $1.62K <0.01% +7 13F-HR Timeline Institute for Wealth Management, LLC. More: the full row for Institute for Wealth Management, LLC. 30 $1.53K <0.01% new 13F-HR Timeline PNC Financial Services Group, Inc. in group PNC Financial Services Group,… More: the full row for PNC Financial Services Group, Inc. 22 $1.12K <0.01% 0 13F-HR Timeline Group Covestor Ltd More: the full row for Covestor Ltd 15 $1K <0.01% +9 13F-HR Timeline Parallel Advisors, LLC More: the full row for Parallel Advisors, LLC 17 $863 <0.01% new 13F-HR Timeline NATIONAL BANK OF CANADA /FI/ in group NATIONAL BANK OF CANADA /FI/ More: the full row for NATIONAL BANK OF CANADA /FI/ 7 $355 <0.01% new 13F-HR Timeline Group FIFTH THIRD BANCORP in group FIFTH THIRD BANK, NATIONAL AS… More: the full row for FIFTH THIRD BANCORP 4 $226 <0.01% new 13F-HR Timeline Group