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Disclosery

GPCR STRUCTURE THERAPEUTICS INC

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EQUITY (ADR), issuer CIK 1888886

189 managers (192 13F filers) reported a position in GPCR shares at 2026-06-30, 67,559,599 shares in all. 28 filers opened a position and 31 filers sold out during the quarter.

Managers
189
13F filers
192
New
28
Added
75
Reduced
51
Sold out
31
Shares held by filers
67,559,599

Shares held by filers adds up every 13F filer's report, so a share reported by a parent and by its subsidiary counts twice (H9). Managers counts each filer group once.

13D and 13G filers

No 13D or 13G on this security in the data. Structured 13D/G data starts 2024-12-18.

Insider trades

No Form 4 transaction on this security in the data.

13F holders, Q2 2026

Filers in the available 13F reports with a share position at 2026-06-30, filer groups collapsed to one row (method), largest first. Options and principal amounts are left out. A group row states no % of portfolio, since each member reports its own portfolio: the members' percents are listed under it. A value about 1,000 times or 1/1,000 of the price other filers imply is shown as filed but neither ranks the row nor enters a sum.

HolderSharesValue% of portfolioChangeSource
FMR LLCin group FMR LLC7,810,306$419M0.02%-593,14313F-HRTimelineGroup
WELLINGTON MANAGEMENT GROUP LLPin group WELLINGTON MANAGEMENT GROUP L…7,379,433$396M0.07%+119,14613F-HRTimelineGroup
Avoro Capital Advisors LLC6,555,555$352M3.16%013F-HRTimeline
Jupiter Topco LLCin group Janus Henderson5,204,212$279M0.11%13F-HRTimelineGroup
Deep Track Capital, LP4,740,072$254M3.75%+460,22413F-HRTimeline
BVF INC/ILin group BVF INC/IL3,366,823$181M4.62%-92,53513F-HRTimelineGroup
MORGAN STANLEYin group MORGAN STANLEY2,806,640$151M0.01%+501,18313F-HRTimelineGroup
ORBIMED ADVISORS LLCin group ORBIMED ADVISORS LLC2,209,400$119M2.25%+733,99713F-HRTimelineGroup
PRINCIPAL FINANCIAL GROUP INCin group PRINCIPAL FINANCIAL GROUP INC1,752,753$94.1M0.05%-1,01113F-HRTimelineGroup
AMERICAN CENTURY COMPANIES INCin group AMERICAN CENTURY COMPANIES INC1,682,179$90.3M0.04%+244,14813F-HRTimelineGroup
RTW INVESTMENTS, LP1,607,507$86.3M0.74%new13F-HRTimeline
Driehaus Capital Management LLC1,553,219$83.4M0.48%-24,13713F-HRTimeline
BAKER BROS. ADVISORS LPin group BAKER BROS. ADVISORS LP1,432,529$76.9M0.39%013F-HRTimelineGroup
Casdin Capital, LLC1,175,000$63.1M3.16%013F-HRTimeline
DEERFIELD MANAGEMENT COMPANY, L.P.in group DEERFIELD MANAGEMENT COMPANY,…1,086,000$58.3M0.61%+318,00713F-HRTimelineGroup
CAPITOLIS LIQUID GLOBAL MARKETS LLC1,041,100$55.9M0.24%-110,20013F-HRTimeline
Siren, L.L.C.in group Siren, L.L.C.872,967$46.9M0.95%-455,73113F-HRTimelineGroup
PRICE T ROWE ASSOCIATES INC /MD/845,532$45.4M<0.01%-1,155,16413F-HRTimeline
Pacific Heights Asset Management LLC800,000$42.9M1.36%+50,00013F-HRTimeline
Rock Springs Capital Management LP640,317$34.4M1.68%+10013F-HRTimeline
Aberdeen Group plcin group Aberdeen Group plc639,915$34.3M0.05%+248,10613F-HRTimelineGroup
FRANKLIN RESOURCES INCin group Franklin Resources578,839$31.1M0.01%+47,24413F-HRTimelineGroup
BANK OF AMERICA CORP /DE/in group BANK OF AMERICA CORP /DE/563,422$30.2M<0.01%+336,29013F-HRTimelineGroup
ALLIANCEBERNSTEIN L.P.611,708$29.5M0.01%-27,10513F-HRTimeline
BlackRock, Inc.in group BlackRock, Inc.511,149$27.4M<0.01%+69,17413F-HRTimelineGroup
Logos Global Management LP500,000$26.8M1.16%013F-HRTimeline
Parkman Healthcare Partners LLC485,661$26.1M2.68%+253,56813F-HRTimeline
Davern Capital Partners, LP446,059$23.9M4.08%+319,59813F-HRTimeline
HEALTHCARE OF ONTARIO PENSION PLAN TRUS…418,800$22.5M0.03%-49,00013F-HRTimeline
UBS Group AGin group UBS Group AG378,986$20.3M<0.01%+166,06713F-HRTimelineGroup
DEUTSCHE BANK AG\in group DEUTSCHE BANK AG\331,867$17.8M0.01%013F-HRTimelineGroup
NEXTBio Capital Management LP312,496$16.8M7.71%+179,25713F-HRTimeline
Catalio Capital Management, LP276,550$14.8M2.79%+21,17113F-HRTimeline
SUSQUEHANNA INTERNATIONAL GROUP, LLPgroup of 2 filers holding271,292$14.6M+154,933Timeline
MARSHALL WACE, LLPin group MARSHALL WACE, LLP267,592$14.4M0.01%+198,48513F-HRTimelineGroup
HSG Holding Ltdin group HSG Holding Ltd266,062$14.3M1.19%013F-HRTimelineGroup
SEB Asset Management AB245,043$13.2M0.05%013F-HRTimeline
GOLDMAN SACHS GROUP INCin group GOLDMAN SACHS GROUP INC242,790$13M<0.01%-17,75313F-HRTimelineGroup
AMERIPRISE FINANCIAL INCin group AMERIPRISE FINANCIAL INC230,514$12.4M<0.01%+10,99813F-HRTimelineGroup
NATIONAL BANK OF CANADA /FI/in group NATIONAL BANK OF CANADA /FI/215,800$11.6M0.01%-89,60013F-HRTimelineGroup
NOMURA ASSET MANAGEMENT CO LTDgroup of 3 filers holding208,782$11.2M+41,977Timeline
TWO SIGMA INVESTMENTS, LPin group TWO SIGMA INVESTMENTS, LP204,156$11M0.01%+22,74113F-HRTimelineGroup
Eversept Partners, LP196,302$10.5M0.57%+58,26613F-HRTimeline
Schonfeld Strategic Advisors LLC190,685$10.2M0.05%+25,25913F-HRTimeline
Woodline Partners LP153,808$8.25M0.03%-37,00013F-HRTimeline
ArrowMark Colorado Holdings LLC150,579$8.08M0.34%-37,61613F-HRTimeline
CenterBook Partners LP148,030$7.94M0.39%+126,79313F-HRTimeline
Rhenman & Partners Asset Management AB145,100$7.79M0.74%+17,00013F-HRTimeline
B Group, Inc.140,000$7.51M4.26%+12,50013F-HRTimeline
HighVista Strategies LLC130,784$7.02M1.6%+6,87513F-HRTimeline
Universal- Beteiligungs- und Serviceges…in group Universal- Beteiligungs- und …125,689$6.75M0.01%+16,05113F-HRTimelineGroup
Squarepoint Ops LLCin group Squarepoint Ops LLC125,575$6.74M0.01%+102,92913F-HRTimelineGroup
D. E. Shaw & Co., Inc.in group D. E. Shaw & Co., Inc.115,300$6.19M<0.01%-89,49013F-HRTimelineGroup
VOLORIDGE INVESTMENT MANAGEMENT, LLC112,300$6.03M0.03%-142,66913F-HRTimeline
Soleus Capital Management, L.P.107,000$5.74M0.2%+27,00013F-HRTimeline
Avidity Partners Management LP98,000$5.26M0.84%+68,00013F-HRTimeline
GEODE CAPITAL MANAGEMENT, LLCin group GEODE CAPITAL MANAGEMENT, LLC97,183$5.22M<0.01%+29,32113F-HRTimelineGroup
Qube Research & Technologies Ltd93,403$5.01M0.01%+19,80413F-HRTimeline
PEREGRINE CAPITAL MANAGEMENT LLC92,229$4.95M0.16%-4,88813F-HRTimeline
PFM Health Sciences, LP91,550$4.91M0.43%-34,83313F-HRTimeline
PLATINUM INVESTMENT MANAGEMENT LTD90,363$4.85M1.19%+23,49913F-HRTimeline
MILLENNIUM MANAGEMENT LLCin group MILLENNIUM MANAGEMENT LLC89,568$4.81M<0.01%-79,36313F-HRTimelineGroup
ExodusPoint Capital Management, LP78,266$4.2M0.04%new13F-HRTimeline
ADAGE CAPITAL PARTNERS GP, L.L.C.in group ADAGE CAPITAL PARTNERS GP, L.…75,000$4.03M0.01%new13F-HRTimelineGroup
Cormorant Asset Management, LP75,000$4.03M0.21%-100,00013F-HRTimeline
Boxer Capital Management, LLC75,000$4.03M0.3%013F-HRTimeline
ALPS ADVISORS INC71,833$3.86M0.02%+14,16613F-HRTimeline
TD Asset Management Inc68,962$3.7M<0.01%-135,80013F-HRTimeline
Brevan Howard Capital Management LPin group Brevan Howard Capital Managem…60,336$3.26M0.05%+13,07013F-HRTimelineGroup
Burkehill Global Management, LP60,000$3.22M0.12%013F-HRTimeline
RAYMOND JAMES FINANCIAL INCin group RAYMOND JAMES FINANCIAL INC59,357$3.19M<0.01%+14,21813F-HRTimelineGroup
TUDOR INVESTMENT CORP ET AL53,656$2.88M0.01%-21,64513F-HRTimeline
ANTIPODES PARTNERS Ltd51,262$2.75M0.05%+5,90113F-HRTimeline
SEVEN GRAND MANAGERS, LLC50,000$2.68M0.11%013F-HRTimeline
Buckland Partners Management Co LLC50,000$2.68M1.31%013F-HRTimeline
DAFNA Capital Management LLC46,500$2.5M0.48%013F-HRTimeline
Mariner, LLCin group Mariner, LLC46,285$2.48M<0.01%+11,80513F-HRTimelineGroup
OSAIC HOLDINGS, INC.in group OSAIC HOLDINGS, INC.44,786$2.4M<0.01%+37013F-HRTimelineGroup
STATE STREET CORPin group STATE STREET CORP44,629$2.4M<0.01%-2,95213F-HRTimelineGroup
VOYA INVESTMENT MANAGEMENT LLCin group VOYA INVESTMENT MANAGEMENT LLC44,410$2.38M<0.01%013F-HRTimelineGroup
BANQUE PICTET & CIE SA43,332$2.33M0.02%-6,03513F-HRTimeline
Jump Financial, LLCin group Jump Financial, LLC42,658$2.29M0.02%-65,19913F-HRTimelineGroup
BANK OF MONTREAL /CAN/in group BANK OF MONTREAL /CAN/42,570$2.28M<0.01%+2,58613F-HRTimelineGroup
Cinctive Capital Management LP40,877$2.19M0.09%+32,16313F-HRTimeline
Jefferies Financial Group Inc.in group Jefferies Financial Group Inc.40,625$2.18M0.02%-21,96713F-HRTimelineGroup
Jones Hill Capital LP40,567$2.18M0.46%-60,02613F-HRTimeline
STEMPOINT CAPITAL LP38,178$2.05M0.35%-162,08913F-HRTimeline
MANUFACTURERS LIFE INSURANCE COMPANY, T…in group MANUFACTURERS LIFE INSURANCE …38,108$2.05M<0.01%-76,70613F-HRTimelineGroup
CAPITAL FUND MANAGEMENT S.A.37,281$2M0.01%+4,84513F-HRTimeline
PSquared Asset Management AG37,200$2M0.65%+2,20013F-HRTimeline
FLAX POND CAPITAL, LLC36,000$1.93M1.35%013F-HR/ATimeline
TrueMark Investments, LLCin group TrueMark Investments, LLC33,600$1.8M0.23%-77713F-HRTimelineGroup
DCF Advisers, LLC32,100$1.72M0.45%+4,60013F-HRTimeline
EXCHANGE TRADED CONCEPTS, LLC30,773$1.65M0.01%+5,39513F-HR/ATimeline
Private Capital Advisors, Inc.29,760$1.6M0.14%-4,62913F-HRTimeline
GSA CAPITAL PARTNERS LLP28,665$1.54M0.1%+14,85413F-HRTimeline
SPHERA FUNDS MANAGEMENT LTD.in group SPHERA FUNDS MANAGEMENT LTD.28,600$1.53M0.22%-22,20013F-HRTimelineGroup
Verition Fund Management LLC28,519$1.53M0.01%+44513F-HR/ATimeline
Y-Intercept (Hong Kong) Ltd27,573$1.48M0.03%new13F-HRTimeline
Seven Fleet Capital Management LP26,800$1.44M0.24%+17,80013F-HRTimeline
MML INVESTORS SERVICES, LLC25,601$1.37M<0.01%+11,71413F-HRTimeline
Birchview Capital, LP24,000$1.29M0.6%-76,00013F-HRTimeline
BARCLAYS PLCin group BARCLAYS PLC20,231$1.09M<0.01%+1,04313F-HRTimelineGroup
Handelsbanken Fonder AB19,400$1.04M<0.01%new13F-HRTimeline
BNP PARIBAS FINANCIAL MARKETSin group BNP PARIBAS FINANCIAL MARKETS17,781$954K<0.01%+6,90213F-HRTimelineGroup
ADAR1 Capital Management, LLCin group ADAR1 Capital Management, LLC17,500$939K0.04%new13F-HRTimelineGroup
TEACHERS RETIREMENT SYSTEM OF THE STATE…17,297$928K0.01%013F-HRTimeline
STIFEL FINANCIAL CORPin group STIFEL FINANCIAL CORP15,032$807K<0.01%+3,69013F-HRTimelineGroup
LPL Financial LLC14,333$769K<0.01%+5,07313F-HRTimeline
WEXFORD CAPITAL LP13,709$736K0.1%013F-HRTimeline
SEI INVESTMENTS COin group SEI INVESTMENTS CO13,684$734K<0.01%-30613F-HRTimelineGroup
BRANDYWINE MANAGERS, LLCin group BRANDYWINE MANAGERS, LLC13,357$717K0.35%013F-HRTimelineGroup
Gladstone Institutional Advisory LLC13,275$712K0.02%new13F-HRTimeline
Fulcrum Asset Management LLP13,252$685K0.07%new13F-HRTimeline
China Universal Asset Management Co., L…12,409$666K0.04%-1,41513F-HRTimeline
ENVESTNET ASSET MANAGEMENT INCin group ENVESTNET ASSET MANAGEMENT INC11,575$621K<0.01%+19813F-HRTimelineGroup
Verdad Advisers, LP11,335$608K0.58%013F-HRTimeline
DNB Asset Management ASin group DNB Asset Management AS10,779$579K<0.01%+2,59113F-HRTimelineGroup
FOX RUN MANAGEMENT, L.L.C.10,776$578K0.1%new13F-HRTimeline
WELLS FARGO & COMPANY/MNin group WELLS FARGO & COMPANY/MN10,398$558K<0.01%+2,58013F-HRTimelineGroup
HighTower Advisors, LLC10,029$538K<0.01%+40913F-HRTimeline
Quinn Opportunity Partners LLC10,000$537K0.03%013F-HRTimeline
SmartHarvest Portfolios, LLC9,928$533K0.17%+87213F-HRTimeline
CITIGROUP INCin group CITIGROUP INC9,680$520K<0.01%-10,81413F-HRTimelineGroup
Gilbert & Cook, Inc.9,167$492K0.06%-2613F-HRTimeline
IMC-Chicago, LLC8,618$463K<0.01%new13F-HRTimeline
SIMPLEX TRADING, LLC7,871$422K0.01%new13F-HRTimeline
Clearstead Advisors, LLC7,826$420K<0.01%new13F-HRTimeline
Allianz Asset Management GmbHin group Allianz SE8,600$415K<0.01%013F-HRTimelineGroup
Quadcap Wealth Management, LLC7,635$410K0.04%+2,90613F-HRTimeline
Virtus Investment Advisers, LLCin group Virtus Investment Advisers, L…7,622$409K0.1%+3,55713F-HRTimelineGroup
MISSION WEALTH MANAGEMENT, LP7,583$407K0.01%013F-HRTimeline
Vestmark Advisory Solutions, Inc.7,534$404K<0.01%013F-HRTimeline
Parallel Advisors, LLC7,352$395K0.01%013F-HRTimeline
Cetera Investment Advisers6,638$356K<0.01%-1,08213F-HRTimeline
EntryPoint Capital, LLC6,136$329K0.08%new13F-HRTimeline
Janney Montgomery Scott LLC5,364$288K<0.01%-1,45513F-HRTimeline
Mirae Asset Global Investments Co., Ltd.in group Mirae Asset Global Investment…5,107$274K<0.01%-1,30413F-HRTimelineGroup
NORTHERN TRUST CORPin group NORTHERN TRUST CORP5,080$273K<0.01%new13F-HRTimelineGroup
Concurrent Investment Advisors, LLCin group Concurrent Investment Advisor…5,000$268K<0.01%013F-HRTimelineGroup
Bellevue Group AGin group Bellevue Group AG4,762$256K0.01%-2,04113F-HRTimelineGroup
Arrowpoint Investment Partners (Singapo…in group Arrowpoint Investment Partner…4,645$249K0.07%+45513F-HRTimelineGroup
Independent Advisor Alliance4,543$244K0.01%-2,90113F-HRTimeline
SECTORAL ASSET MANAGEMENT INC4,325$232K0.16%-9,77713F-HRTimeline
PEAK6 LLCin group PEAK6 LLC4,155$223K0.01%-1,90013F-HRTimelineGroup
Walleye Capital LLCgroup of 2 filers holding4,113$221K-17,247Timeline
Prospera Financial Services Inc4,100$220K<0.01%new13F-HRTimeline
GABELLI FUNDS LLCin group GAMCO Investors (Gabelli)4,050$217K<0.01%new13F-HRTimelineGroup
Invesco Ltd.in group Invesco Ltd.3,951$212K<0.01%-63013F-HRTimelineGroup
JPMORGAN CHASE & COin group JPMORGAN CHASE & CO3,984$206K<0.01%-208,81913F-HRTimelineGroup
NANO CAP NEW MILLENNIUM GROWTH FUND L P3,500$188K0.14%+2,00013F-HRTimeline
E. Ohman J:or Asset Management AB3,212$172K<0.01%-1,30613F-HRTimeline
State of Wyoming3,101$166K0.02%+2,66813F-HRTimeline
PNC Financial Services Group, Inc.in group PNC Financial Services Group,…2,782$149K<0.01%-7213F-HRTimelineGroup
ASSETMARK, INCin group ASSETMARK, INC2,726$146K<0.01%+18213F-HRTimelineGroup
NATIXISin group Natixis Investment Managers2,482$135K<0.01%new13F-HRTimelineGroup
Rockefeller Capital Management L.P.in group Rockefeller Capital Managemen…2,514$135K<0.01%+29413F-HRTimelineGroup
SG Americas Securities, LLC2,427$130K<0.01%-22213F-HRTimeline
Sterling Capital Management LLC2,045$110K<0.01%+1,45513F-HRTimeline
Farther Finance Advisors, LLC1,656$88.9K<0.01%+72513F-HRTimeline
GF FUND MANAGEMENT CO. LTD.1,651$88.6K<0.01%+15113F-HRTimeline
Federation des caisses Desjardins du Qu…1,500$80.5K<0.01%new13F-HRTimeline
Steward Partners Investment Advisory, L…1,400$75.1K<0.01%013F-HRTimeline
Tower Research Capital LLC (TRC)in group Tower Research Capital LLC (T…897$48.1K<0.01%+25113F-HRTimelineGroup
IFP Advisors, Inc858$46K<0.01%new13F-HRTimeline
GAMMA Investing LLC836$44.9K<0.01%-16313F-HRTimeline
ROYAL BANK OF CANADAin group ROYAL BANK OF CANADA550$30K<0.01%-17213F-HRTimelineGroup
WOLFF WIESE MAGANA LLC400$21.5K0.01%013F-HRTimeline
Zurcher Kantonalbank (Zurich Cantonalba…385$20.7K<0.01%+17313F-HRTimeline
North Star Investment Management Corp.330$17.7K<0.01%013F-HRTimeline
Integrated Wealth Concepts LLC271$14.5K<0.01%new13F-HRTimeline
Quarry LP245$13.1K<0.01%new13F-HRTimeline
Godfrey Financial Associates, Inc.245$13.1K0.01%new13F-HRTimeline
JONES FINANCIAL COMPANIES LLLPin group JONES FINANCIAL COMPANIES LLLP175$8.7K<0.01%-16613F-HRTimelineGroup
Dynamic Wealth Strategies, LLC150$8.05K<0.01%013F-HRTimeline
SIGNATUREFD, LLC100$5.37K<0.01%013F-HRTimeline
Key Financial Inc100$5.37K<0.01%013F-HRTimeline
SHP Wealth Management100$5.37K<0.01%013F-HRTimeline
HUNTINGTON NATIONAL BANKin group HUNTINGTON NATIONAL BANK79$4.24K<0.01%+7713F-HRTimelineGroup
Rakuten Securities, Inc.in group Rakuten Group, Inc.60$3.22K<0.01%013F-HRTimelineGroup
Arax Advisory Partners34$1.82K<0.01%new13F-HRTimeline
Transamerica Financial Advisors, LLCin group Transamerica Financial Adviso…22$1.18K<0.01%013F-HRTimelineGroup
Ares Financial Consulting, LLC20$1.07K<0.01%new13F-HRTimeline
BESSEMER GROUP INCin group BESSEMER GROUP INC22$1K<0.01%new13F-HRTimelineGroup
Capital Analysts, LLCin group Capital Analysts, LLC18$1K<0.01%013F-HRTimelineGroup
Smartleaf Asset Management LLC17$879<0.01%013F-HRTimeline
Caitong International Asset Management …10$537<0.01%new13F-HRTimeline
Cullen/Frost Bankers, Inc.in group Cullen/Frost Bankers, Inc.8$429<0.01%013F-HRTimelineGroup
Larson Financial Group LLC6$322<0.01%+113F-HRTimeline