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Ikarian Capital, LLC

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13F filer, CIK 1778253, DALLAS, TX

Ikarian Capital, LLC reported $1,231,685,555 across 161 holdings for the quarter ended 2026-03-31, in a 13F-HR filed 2026-05-15. Its ten largest share positions make up 41.29% of the portfolio.

Filed (acceptance time not in the bulk data set), ingested 13F-HR 0001420506-26-001165

Period
2026-03-31
Reported value
$1.23B
Holdings
161
Top 10 weight
41.29%
New
41
Sold out
54

Part of the filer group Ikarian Capital, LLC

  • Neil Shahrestani
How groups are built

Largest buys vs the previous quarter

SecurityShares changeApprox. value
ALMSnew+1,213,548$26.7M
KODadded+546,008$20.8M
CLDXnew+461,247$14.6M
HROWadded+359,700$12.7M
BBIOnew+160,120$11.9M

Ranked by the share change valued at this quarter's implied price (value over shares in the 13F). A position sold out is valued at the previous quarter's price, its last report.

Largest sells vs the previous quarter

SecurityShares changeApprox. value
CDTXexited-273,243-$60.4M
JAZZreduced-147,907-$28M
RAPTexited-665,271-$22.5M
ABVXreduced-148,350-$16M
AMGNexited-45,000-$14.7M

Ranked by the share change valued at this quarter's implied price (value over shares in the 13F). A position sold out is valued at the previous quarter's price, its last report.

Holdings, Q1 2026

Share positions as resolved from 13F-HR 0001420506-26-001165, largest first. % of portfolio is the value over $699,010,508, the sum of the share positions whose value is usable for ratios (method).

SecurityHistorySharesValue% of portfolioChangeLatest eventTimeline
TERNTERNS PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: 308,497 shares; 2024Q4: 308,491 shares; 2025Q1: 308,491 shares; 2025Q2: 58,491 shares; 2025Q3: 164,202 shares; 2025Q4: 1,596,378 shares; 2026Q1: 1,456,378 shares 1,456,378$76.8M10.98%-140,000Timeline
KODKODIAK SCIENCES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: 476,586 shares; 2024Q4: 576,166 shares; 2025Q1: 649,534 shares; 2025Q2: 599,534 shares; 2025Q3: 413,841 shares; 2025Q4: 719,787 shares; 2026Q1: 1,265,795 shares 1,265,795$48.3M6.9%+546,008Timeline
ALMSALUMIS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: not reported; 2026Q1: 1,213,548 shares 1,213,548$26.7M3.82%newTimeline
PCVXVAXCYTE INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: 200,000 shares; 2025Q2: 305,000 shares; 2025Q3: 311,682 shares; 2025Q4: 378,682 shares; 2026Q1: 428,682 shares 428,682$24.9M3.56%+50,000Timeline
PRAXPRAXIS PRECISION MEDICINES IQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: 145,502 shares; 2025Q2: 276,950 shares; 2025Q3: 28,571 shares; 2025Q4: 86,581 shares; 2026Q1: 71,581 shares 71,581$23.1M3.3%-15,000Timeline
HROWHARROW INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 183,347 shares; 2026Q1: 543,047 shares 543,047$19.1M2.74%+359,700Timeline
RLMDRELMADA THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: 40,369 shares; 2024Q4: 40,270 shares; 2025Q1: 40,270 shares; 2025Q2: 40,270 shares; 2025Q3: 1,843,060 shares; 2025Q4: 3,068,359 shares; 2026Q1: 2,688,359 shares 2,688,359$18.7M2.68%-380,000Timeline
CYTKCYTOKINETICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: 170,147 shares; 2024Q4: 149,982 shares; 2025Q1: 149,982 shares; 2025Q2: 233,464 shares; 2025Q3: 222,674 shares; 2025Q4: 172,672 shares; 2026Q1: 283,572 shares 283,572$18.7M2.67%+110,900Timeline
TENXTENAX THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 967,600 shares; 2025Q4: 967,600 shares; 2026Q1: 1,017,600 shares 1,017,600$16.3M2.33%+50,000Timeline
CAPRCAPRICOR THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: 300,000 shares; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 264,642 shares; 2025Q4: 578,015 shares; 2026Q1: 528,015 shares 528,015$16.1M2.3%-50,000Timeline
RVMDREVOLUTION MEDICINES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 138,142 shares; 2026Q1: 163,142 shares 163,142$15.9M2.27%+25,000Timeline
CLDXCELLDEX THERAPEUTICS INC NEWQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: not reported; 2026Q1: 461,247 shares 461,247$14.6M2.09%newTimeline
PHVSPHARVARIS N VQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 210,165 shares; 2025Q4: 486,856 shares; 2026Q1: 486,856 shares 486,856$13.8M1.97%0Timeline
CNTBCONNECT BIOPHARMA HLDGS LTDQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 4,788,486 shares; 2026Q1: 5,388,486 shares 5,388,486$13.1M1.88%+600,000Timeline
DRUGBRIGHT MINDS BIOSCIENCES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: 152,211 shares; 2025Q1: 65,431 shares; 2025Q2: 65,431 shares; 2025Q3: 15,431 shares; 2025Q4: 159,421 shares; 2026Q1: 166,647 shares 166,647$12.2M1.74%+7,226Timeline
BBIOBRIDGEBIO PHARMA INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: 285,613 shares; 2024Q4: 215,713 shares; 2025Q1: 90,837 shares; 2025Q2: not reported; 2025Q3: 51,967 shares; 2025Q4: not reported; 2026Q1: 160,120 shares 160,120$11.9M1.7%newTimeline
ORKAORUKA THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: 175,000 shares; 2025Q2: 68,574 shares; 2025Q3: not reported; 2025Q4: not reported; 2026Q1: 242,021 shares 242,021$11.9M1.7%newTimeline
ANROALTO NEUROSCIENCE INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: 350,000 shares; 2025Q1: 175,000 shares; 2025Q2: 110,000 shares; 2025Q3: 110,000 shares; 2025Q4: 515,000 shares; 2026Q1: 515,000 shares 515,000$11.6M1.66%0Timeline
SLNOSOLENO THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: 221,437 shares; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 55,946 shares; 2025Q4: 68,823 shares; 2026Q1: 344,123 shares 344,123$11.5M1.65%+275,300Timeline
MAZEMAZE THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: 322,740 shares; 2025Q2: 262,740 shares; 2025Q3: 740,825 shares; 2025Q4: 644,680 shares; 2026Q1: 378,999 shares 378,999$11.3M1.62%-265,681Timeline
ANIPANI PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: not reported; 2026Q1: 147,085 shares 147,085$11.3M1.62%newTimeline
CTNMCONTINEUM THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 282,874 shares; 2026Q1: 807,874 shares 807,874$10.6M1.51%+525,000Timeline
RAREULTRAGENYX PHARMACEUTICAL INQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: 179,000 shares; 2024Q4: 178,989 shares; 2025Q1: 216,989 shares; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 12,671 shares; 2026Q1: 482,571 shares 482,571$10.1M1.45%+469,900Timeline
IONSIONIS PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 415,163 shares; 2025Q4: 202,038 shares; 2026Q1: 127,038 shares 127,038$9.54M1.36%-75,000Timeline
OLMAOLEMA PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: 92,000 shares; 2024Q4: 91,994 shares; 2025Q1: 191,994 shares; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 758,654 shares; 2026Q1: 598,281 shares 598,281$8.92M1.28%-160,373Timeline
EPRXEUPRAXIA PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 610,000 shares; 2026Q1: 1,214,741 shares 1,214,741$8.79M1.26%+604,741Timeline
DMRADAMORA THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 285,710 shares; 2026Q1: 335,710 shares 335,710$8.69M1.24%+50,000Timeline
PVLAPALVELLA THERAPEUTICS INC NEQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 64,746 shares; 2025Q4: not reported; 2026Q1: 64,626 shares 64,626$8.06M1.15%newTimeline
FULCFULCRUM THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: 75,000 shares; 2024Q4: 200,096 shares; 2025Q1: 200,096 shares; 2025Q2: 428,521 shares; 2025Q3: 1,289,225 shares; 2025Q4: 1,375,472 shares; 2026Q1: 1,049,161 shares 1,049,161$8.05M1.15%-326,311Timeline
VERAVERA THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 14,096 shares; 2025Q3: not reported; 2025Q4: not reported; 2026Q1: 200,000 shares 200,000$8.05M1.15%newTimeline
SPRBSPRUCE BIOSCIENCES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 13,332 shares; 2025Q4: 121,356 shares; 2026Q1: 121,356 shares 121,356$7.93M1.13%0Timeline
IVAINVENTIVA SAQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 502,601 shares; 2026Q1: 1,429,101 shares 1,429,101$7.84M1.12%+926,500Timeline
JBIOJADE BIOSCIENCES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 300,000 shares; 2026Q1: 512,349 shares 512,349$7.2M1.03%+212,349Timeline
OCGNOCUGEN INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: not reported; 2026Q1: 3,962,972 shares 3,962,972$7.17M1.03%newTimeline
ZURAZURA BIO LTDQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 2,132,322 shares; 2025Q4: 802,322 shares; 2026Q1: 1,193,492 shares 1,193,492$7.1M1.02%+391,170Timeline
OVIDOVID THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 1,095,574 shares; 2025Q4: 247,558 shares; 2026Q1: 2,894,704 shares 2,894,704$6.43M0.92%+2,647,146Timeline
ABVXABIVAX SAQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 396,098 shares; 2025Q4: 205,985 shares; 2026Q1: 57,635 shares 57,635$6.23M0.89%-148,350Timeline
LLYELI LILLY & COQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 13,815 shares; 2026Q1: 6,547 shares 6,547$6.02M0.86%-7,268Timeline
ACOGALPHA COGNITION INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: 755,867 shares; 2025Q1: 967,867 shares; 2025Q2: 917,867 shares; 2025Q3: 946,259 shares; 2025Q4: 1,056,259 shares; 2026Q1: 1,056,259 shares 1,056,259$5.8M0.83%0Timeline
PTHSPELTHOS THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 62,451 shares; 2025Q4: 255,758 shares; 2026Q1: 256,598 shares 256,598$5.39M0.77%+840Timeline
SRZNSURROZEN INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 65,788 shares; 2026Q1: 173,107 shares 173,107$5.04M0.72%+107,319Timeline
TECXTECTONIC THERAPEUTIC INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: 267,145 shares; 2024Q4: 142,328 shares; 2025Q1: 269,090 shares; 2025Q2: 163,696 shares; 2025Q3: not reported; 2025Q4: not reported; 2026Q1: 157,537 shares 157,537$4.87M0.7%newTimeline
ALECALECTOR INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: 950,000 shares; 2025Q1: 950,000 shares; 2025Q2: 900,000 shares; 2025Q3: 760,000 shares; 2025Q4: 2,082,606 shares; 2026Q1: 2,082,606 shares 2,082,606$4.48M0.64%0Timeline
LEGNLEGEND BIOTECH CORPQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 226,888 shares; 2026Q1: 226,888 shares 226,888$4.1M0.59%0Timeline
KPTIKARYOPHARM THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: 27,257 shares; 2025Q2: 27,257 shares; 2025Q3: 27,257 shares; 2025Q4: 544,554 shares; 2026Q1: 733,435 shares 733,435$4.09M0.58%+188,881Timeline
LPCNLIPOCINE INC NEWQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 199,542 shares; 2026Q1: 508,556 shares 508,556$4.06M0.58%+309,014Timeline
DCTHDELCATH SYS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: 100,370 shares; 2024Q4: 100,365 shares; 2025Q1: 100,365 shares; 2025Q2: 322,390 shares; 2025Q3: 431,251 shares; 2025Q4: 431,251 shares; 2026Q1: 431,251 shares 431,251$4M0.57%0Timeline
ARVNARVINAS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: 229,900 shares; 2025Q2: 850,000 shares; 2025Q3: 226,257 shares; 2025Q4: 358,257 shares; 2026Q1: 358,257 shares 358,257$3.8M0.54%0Timeline
CMPSCOMPASS PATHWAYS PLCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: 202,908 shares; 2024Q4: 202,894 shares; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 400,000 shares; 2026Q1: 675,000 shares 675,000$3.73M0.53%+275,000Timeline
CRDLCARDIOL THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: not reported; 2026Q1: 2,725,000 shares 2,725,000$3.68M0.53%newTimeline
BHVNBIOHAVEN LTDQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 212,481 shares; 2026Q1: 412,481 shares 412,481$3.49M0.5%+200,000Timeline
IVVDINVIVYD INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 2,078,706 shares; 2025Q4: 2,656,570 shares; 2026Q1: 2,656,570 shares 2,656,570$3.45M0.49%0Timeline
ANNXANNEXON INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 230,244 shares; 2026Q1: 580,244 shares 580,244$3.21M0.46%+350,000Timeline
FBRXFORTE BIOSCIENCES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: 609,225 shares; 2025Q1: 609,225 shares; 2025Q2: 476,443 shares; 2025Q3: 300,000 shares; 2025Q4: 300,000 shares; 2026Q1: 118,972 shares 118,972$3.08M0.44%-181,028Timeline
LXEOLEXEO THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: 257,216 shares; 2024Q4: 499,301 shares; 2025Q1: 550,029 shares; 2025Q2: 550,029 shares; 2025Q3: 567,601 shares; 2025Q4: 513,011 shares; 2026Q1: 513,011 shares 513,011$2.94M0.42%0Timeline
FRNMPERCEPTIVE CAP SOLUTIONS CORQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 240,951 shares; 2026Q1: 240,951 shares 240,951$2.64M0.38%0Timeline
VIRVIR BIOTECHNOLOGY INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: 897,862 shares; 2025Q1: 1,068,062 shares; 2025Q2: 1,068,062 shares; 2025Q3: 593,374 shares; 2025Q4: 575,712 shares; 2026Q1: 293,258 shares 293,258$2.63M0.38%-282,454Timeline
NXTCNEXTCURE INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 238,303 shares; 2026Q1: 238,303 shares 238,303$2.51M0.36%0Timeline
NMRANEUMORA THERAPEUTICS INC.Quarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: 15,457 shares; 2025Q2: 12,498 shares; 2025Q3: 12,498 shares; 2025Q4: 1,278,408 shares; 2026Q1: 1,278,408 shares 1,278,408$2.49M0.36%0Timeline
ABOSACUMEN PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: 266,435 shares; 2024Q4: 265,769 shares; 2025Q1: 265,769 shares; 2025Q2: 265,769 shares; 2025Q3: 265,769 shares; 2025Q4: 254,312 shares; 2026Q1: 1,053,797 shares 1,053,797$2.49M0.36%+799,485Timeline
CABACABALETTA BIO INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 900,000 shares; 2026Q1: 900,000 shares 900,000$2.42M0.35%0Timeline
BBOTBRIDGEBIO ONCOLOGY THERAPEUTQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 245,231 shares; 2025Q4: 220,231 shares; 2026Q1: 270,231 shares 270,231$2.42M0.35%+50,000Timeline
PRQRPROQR THRAPEUTICS N VQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: 483,583 shares; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 868,069 shares; 2025Q3: 892,229 shares; 2025Q4: 1,492,229 shares; 2026Q1: 1,492,229 shares 1,492,229$2.42M0.35%0Timeline
NUVLNUVALENT INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: 52,238 shares; 2024Q4: 52,216 shares; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 59,594 shares; 2026Q1: 23,594 shares 23,594$2.42M0.35%-36,000Timeline
JAZZJAZZ PHARMACEUTICALS PLCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 40,000 shares; 2025Q3: 77,800 shares; 2025Q4: 160,367 shares; 2026Q1: 12,460 shares 12,460$2.36M0.34%-147,907Timeline
DBVTDBV TECHNOLOGIES S AQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 525,000 shares; 2026Q1: 525,000 shares 525,000$2.2M0.31%0Timeline
TARSTARSUS PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: 1,030,277 shares; 2024Q4: 607,689 shares; 2025Q1: 485,021 shares; 2025Q2: 196,536 shares; 2025Q3: 73,619 shares; 2025Q4: 31,166 shares; 2026Q1: 31,166 shares 31,166$2.19M0.31%0Timeline
KLRSKALARIS THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 360,000 shares; 2026Q1: 360,000 shares 360,000$2.08M0.3%0Timeline
AVRANTERIS TECHNOLOGIES GLOBALQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: not reported; 2026Q1: 366,571 shares 366,571$2.03M0.29%newTimeline
SLDBSOLID BIOSCIENCES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: 230,000 shares; 2025Q2: not reported; 2025Q3: 176,690 shares; 2025Q4: 160,409 shares; 2026Q1: 264,409 shares 264,409$1.9M0.27%+104,000Timeline
IBIOIBIO INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: 600,000 shares; 2024Q4: 599,913 shares; 2025Q1: 599,913 shares; 2025Q2: 599,913 shares; 2025Q3: 617,327 shares; 2025Q4: 957,062 shares; 2026Q1: 957,062 shares 957,062$1.82M0.26%0Timeline
CPIXCUMBERLAND PHARMACEUTICALS IQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: 740,000 shares; 2025Q2: 595,932 shares; 2025Q3: 555,932 shares; 2025Q4: 555,932 shares; 2026Q1: 553,153 shares 553,153$1.8M0.26%-2,779Timeline
SLNSILENCE THERAPEUTICS PLCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: 587,343 shares; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 873,568 shares; 2025Q3: 900,784 shares; 2025Q4: 865,784 shares; 2026Q1: 865,784 shares 865,784$1.73M0.25%0Timeline
LABDDIREXION SHARES ETF TRUSTQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 91,959 shares; 2025Q4: 40,822 shares; 2026Q1: 105,822 shares 105,822$1.72M0.25%+65,000Timeline
QUREUNIQURE NVQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 119,986 shares; 2025Q3: 58,610 shares; 2025Q4: 91,060 shares; 2026Q1: 91,060 shares 91,060$1.49M0.21%0Timeline
QNRXQUOIN PHARMACEUTICALS LTDQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 211,538 shares; 2026Q1: 211,538 shares 211,538$1.4M0.2%02026-09-30, 13G/A: 211,538 shares, 4.4% of the class, 13G/A filed 2026-10-07 Timeline
TRAWTRAWS PHARMA INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: 98,493 shares; 2025Q1: 28,493 shares; 2025Q2: 28,493 shares; 2025Q3: 28,493 shares; 2025Q4: 678,142 shares; 2026Q1: 678,142 shares 678,142$1.24M0.18%0Timeline
DERMJOURNEY MED CORPQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 251,436 shares; 2026Q1: 251,436 shares 251,436$1.18M0.17%0Timeline
VSTMVERASTEM INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 213,865 shares; 2026Q1: 213,865 shares 213,865$1.13M0.16%0Timeline
DFTXDEFINIUM THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: not reported; 2026Q1: 58,803 shares 58,803$1.11M0.16%newTimeline
STIMNEURONETICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: 1,100,000 shares; 2025Q2: 1,099,700 shares; 2025Q3: 905,716 shares; 2025Q4: 701,182 shares; 2026Q1: 701,182 shares 701,182$1.02M0.15%0Timeline
LYELLYELL IMMUNOPHARMA INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 43,799 shares; 2025Q3: 43,799 shares; 2025Q4: 41,081 shares; 2026Q1: 41,081 shares 41,081$824K0.12%0Timeline
PEPGPEPGEN INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: 150,000 shares; 2025Q2: 150,000 shares; 2025Q3: 535,967 shares; 2025Q4: 447,165 shares; 2026Q1: 447,165 shares 447,165$791K0.11%0Timeline
KZRKEZAR LIFE SCIENCES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: 106,901 shares; 2025Q1: 106,901 shares; 2025Q2: 106,901 shares; 2025Q3: 106,901 shares; 2025Q4: 102,211 shares; 2026Q1: 102,211 shares 102,211$758K0.11%0Timeline
IMUXIMMUNIC INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: 493,496 shares; 2024Q4: 1,614,170 shares; 2025Q1: 914,170 shares; 2025Q2: 914,170 shares; 2025Q3: 914,170 shares; 2025Q4: 674,662 shares; 2026Q1: 674,662 shares 674,662$749K0.11%0Timeline
CNTACENTESSA PHARMACEUTICALS PLCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: not reported; 2026Q1: 18,113 shares 18,113$719K0.1%newTimeline
KALVKALVISTA PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 198,528 shares; 2025Q3: not reported; 2025Q4: 35,119 shares; 2026Q1: 35,119 shares 35,119$707K0.1%0Timeline
PMNPROMIS NEUROSCIENCES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: not reported; 2026Q1: 55,000 shares 55,000$698K0.1%newTimeline
INSMINSMED INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: 154,835 shares; 2024Q4: 119,800 shares; 2025Q1: 84,800 shares; 2025Q2: 163,751 shares; 2025Q3: 13,751 shares; 2025Q4: 9,337 shares; 2026Q1: 4,214 shares 4,214$689K0.1%-5,123Timeline
HELPCYBIN INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: 367,195 shares; 2024Q4: 397,175 shares; 2025Q1: 397,175 shares; 2025Q2: 140,475 shares; 2025Q3: 140,475 shares; 2025Q4: 132,153 shares; 2026Q1: 132,153 shares 132,153$634K0.09%0Timeline
ACADACADIA PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: not reported; 2026Q1: 28,099 shares 28,099$625K0.09%newTimeline
WVEWAVE LIFE SCIENCES LTDQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: 544,265 shares; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 161,137 shares; 2025Q3: 95,955 shares; 2025Q4: 85,285 shares; 2026Q1: 85,285 shares 85,285$618K0.09%0Timeline
EQEQUILLIUM INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 332,297 shares; 2025Q4: 303,555 shares; 2026Q1: 303,555 shares 303,555$607K0.09%0Timeline
PASGPASSAGE BIO INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: not reported; 2026Q1: 68,124 shares 68,124$535K0.08%newTimeline
GUTSFRACTYL HEALTH INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 1,800,000 shares; 2025Q4: 1,100,000 shares; 2026Q1: 1,100,000 shares 1,100,000$504K0.07%0Timeline
PALIPALISADE BIO INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 274,978 shares; 2026Q1: 274,978 shares 274,978$481K0.07%0Timeline
IMTXIMMATICS N.VQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: 49,415 shares; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 49,396 shares; 2025Q3: 49,396 shares; 2025Q4: 48,569 shares; 2026Q1: 48,569 shares 48,569$478K0.07%0Timeline
VKTXVIKING THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: 50,000 shares; 2025Q2: 100,000 shares; 2025Q3: 10,000 shares; 2025Q4: 9,717 shares; 2026Q1: 9,717 shares 9,717$316K0.05%0Timeline
SGMOQSANGAMO THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: 1,860,179 shares; 2025Q1: 1,860,179 shares; 2025Q2: 1,260,179 shares; 2025Q3: 1,294,652 shares; 2025Q4: 1,218,671 shares; 2026Q1: 1,218,671 shares 1,218,671$301K0.04%0Timeline
VTGNVISTAGEN THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: 77,616 shares; 2025Q1: 601,703 shares; 2025Q2: 601,703 shares; 2025Q3: 620,869 shares; 2025Q4: 519,077 shares; 2026Q1: 519,077 shares 519,077$297K0.04%0Timeline
VERUVERU INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 142,523 shares; 2025Q4: 133,517 shares; 2026Q1: 133,517 shares 133,517$295K0.04%0Timeline
EVAXEVAXION ASQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: 80,000 shares; 2025Q2: 80,000 shares; 2025Q3: 80,000 shares; 2025Q4: 74,698 shares; 2026Q1: 74,698 shares 74,698$278K0.04%0Timeline
LXRXLEXICON PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: 1,550,000 shares; 2025Q1: 1,417,952 shares; 2025Q2: 176,479 shares; 2025Q3: 176,479 shares; 2025Q4: 164,674 shares; 2026Q1: 164,674 shares 164,674$257K0.04%0Timeline
ANLADLAI NORTYE GROUP LTDQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: not reported; 2026Q1: 33,899 shares 33,899$235K0.03%newTimeline
MGNXMACROGENICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: 80,079 shares; 2024Q4: 80,071 shares; 2025Q1: 80,071 shares; 2025Q2: 80,071 shares; 2025Q3: 80,071 shares; 2025Q4: 74,893 shares; 2026Q1: 74,893 shares 74,893$216K0.03%0Timeline
VYGRVOYAGER THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: 55,857 shares; 2024Q4: 55,766 shares; 2025Q1: 55,766 shares; 2025Q2: 55,766 shares; 2025Q3: 55,766 shares; 2025Q4: 53,063 shares; 2026Q1: 53,063 shares 53,063$205K0.03%0Timeline
FTHFAETH THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 22,497 shares; 2025Q3: 22,497 shares; 2025Q4: 21,351 shares; 2026Q1: 6,351 shares 6,351$200K0.03%-15,000Timeline
NEUPNEUPHORIA THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 47,443 shares; 2026Q1: 47,443 shares 47,443$193K0.03%0Timeline
VYNEVYNE THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 290,000 shares; 2025Q3: 290,000 shares; 2025Q4: 264,912 shares; 2026Q1: 264,912 shares 264,912$158K0.02%0Timeline
PURRHYPERLIQUID STRATEGIES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 30,001 shares; 2026Q1: 30,001 shares 30,001$153K0.02%0Timeline
NYXHNYXOAH S AQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: 50,699 shares; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 50,627 shares; 2025Q3: 50,627 shares; 2025Q4: 47,358 shares; 2026Q1: 47,358 shares 47,358$138K0.02%0Timeline
RNACCARTESIAN THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: 52,193 shares; 2024Q4: 52,166 shares; 2025Q1: 22,166 shares; 2025Q2: 22,166 shares; 2025Q3: 22,166 shares; 2025Q4: 20,807 shares; 2026Q1: 20,807 shares 20,807$128K0.02%0Timeline
PMVPPMV PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 97,500 shares; 2025Q4: 89,136 shares; 2026Q1: 89,136 shares 89,136$111K0.02%0Timeline
CNSPCNS PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 45,830 shares; 2026Q1: 45,830 shares 45,830$110K0.02%0Timeline
CMPXCOMPASS THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 800,000 shares; 2026Q1: 18,000 shares 18,000$95.2K0.01%-782,000Timeline
IOBTQIO BIOTECH INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 1,525,893 shares; 2025Q4: 1,386,565 shares; 2026Q1: 1,386,565 shares 1,386,565$81.4K0.01%0Timeline
CMMBCHEMOMAB THERAPEUTICS LTDQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 53,262 shares; 2025Q4: 51,793 shares; 2026Q1: 51,793 shares 51,793$81.3K0.01%0Timeline
PHGEBIOMX INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 19,473 shares; 2026Q1: 19,473 shares 19,473$73.1K0.01%0Timeline
RZLTREZOLUTE INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: 887,230 shares; 2024Q4: 857,230 shares; 2025Q1: 50,058 shares; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 16,479 shares; 2026Q1: 16,479 shares 16,479$50.3K0.01%0Timeline
MGRXMANGOCEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 138,146 shares; 2026Q1: 138,146 shares 138,146$49.7K0.01%0Timeline
SHPHSHUTTLE PHARMACTCLS HLDGS INQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 68,993 shares; 2026Q1: 68,993 shares 68,993$46.8K0.01%0Timeline
AIRSAIRSCULPT TECHNOLOGIES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 17,951 shares; 2025Q3: 17,951 shares; 2025Q4: 16,398 shares; 2026Q1: 16,398 shares 16,398$46.4K0.01%0Timeline
AEMDAETHLON MED INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 14,364 shares; 2026Q1: 14,364 shares 14,364$31.5K<0.01%0Timeline
GCTKGLUCOTRACK INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 45,830 shares; 2026Q1: 45,830 shares 45,830$29.8K<0.01%0Timeline
TOVXTHERIVA BIOLOGICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: 120,031 shares; 2025Q2: 120,031 shares; 2025Q3: 120,031 shares; 2025Q4: 112,076 shares; 2026Q1: 112,076 shares 112,076$21.9K<0.01%0Timeline
JSPRJASPER THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: 55,175 shares; 2024Q4: 55,107 shares; 2025Q1: 25,107 shares; 2025Q2: 25,107 shares; 2025Q3: 25,107 shares; 2025Q4: 24,093 shares; 2026Q1: 24,093 shares 24,093$21.1K<0.01%0Timeline
AMIXAUTONOMIX MED INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: 20,000 shares; 2025Q1: 20,000 shares; 2025Q2: 20,000 shares; 2025Q3: 20,000 shares; 2025Q4: 18,688 shares; 2026Q1: 18,688 shares 18,688$7.29K<0.01%0Timeline

Options

Puts and calls, as filed. The amount and value describe the underlying shares, not the option premium, so they stay out of % of portfolio (H5).

SecurityTypeAmountValueChange
XBISPDR SERIES TRUST S&P BIOTECHput800,000$102M-50,000
TERNTERNS PHARMACEUTICALS INC Stockput1,200,000$63.3Mnew
QQQINVESCO QQQ TR COMput100,000$57.7Mnew
IWMISHARES TR SHSput200,000$49.6Mnew
CYTKCYTOKINETICS INC COM NEWput550,500$36.3Mnew
ABVXABIVAX SA SPONSORED ADScall293,300$32.7M+168,200
BMYBRISTOL-MYERS SQUIBB CO COMput500,000$30.3Mnew
CYTKCYTOKINETICS INC COM NEWcall408,400$26.9M+117,500
NVONOVO-NORDISK A S ADRcall400,000$14.7Mnew
ANIPANI PHARMACEUTICALS INC COMcall150,000$11.5M+67,200
CAPRCAPRICOR THERAPEUTICS INC COMMON STOCKcall350,000$10.6Mnew
RVMDREVOLUTION MEDICINES INC Stockput95,000$9.24Mnew
IONSIONIS PHARMACEUTICALS INC Stockcall112,100$8.42M+17,500
OLMAOLEMA PHARMACEUTICALS INC COMcall549,800$8.2M+349,800
AVTXAVALO THERAPEUTICS INC COMMON STOCKcall401,500$5.99M+343,400
ALMSALUMIS INC COMcall264,600$5.83Mnew
UNIQURE NVUNIQURE NV CALLcall355,000$5.8M+249,600
KPTIKARYOPHARM THERAPEUTICS INC COMMON STOCKput920,000$5.12Mnew
KPTIKARYOPHARM THERAPEUTICS INC COMMON STOCKcall920,000$5.12Mnew
EYPTEYEPOINT INC Stockput370,400$4.77Mnew
EYPTEYEPOINT INC Stockcall370,400$4.77Mnew
BBIOBRIDGEBIO PHARMA INC COMcall58,500$4.34Mnew
KYMRKYMERA THERAPEUTICS INC COMput50,400$4.2Mnew
KODKODIAK SCIENCES INC COMcall100,000$3.81Mnew
CLDXCELLDEX THERAPEUTICS INC NEW COM NEWput114,000$3.62Mnew
ARWRARROWHEAD PHARMACEUTICALS IN COMput57,500$3.61Mnew
ELVNENLIVEN THERAPEUTICS INC Stockput83,700$3.28Mnew
VERAVERA THERAPEUTICS INC COMMON STOCKcall71,700$2.88Mnew
AVTXAVALO THERAPEUTICS INC COMMON STOCKput158,500$2.37Mnew
REPLREPLIMUNE GROUP INC COMMON STOCKput300,000$2.29Mnew
TENXTENAX THERAPEUTICS INC COM NEWcall114,300$1.83Mnew
PEPGPEPGEN INC Stockcall300,000$531K0
MAZEMAZE THERAPEUTICS INC Stockput14,400$430Knew
CNTBCONNECT BIOPHARMA HLDGS LTD SHScall144,600$379K0

Sold out in Q1 2026

Positions in the previous quarter's report that this quarter's report no longer lists.

SecurityShares beforeValue beforeType
CDTXCIDARA THERAPEUTICS INC300,000$66.3Mput
AMGNAMGEN INC200,000$65.5Mput
CDTXCIDARA THERAPEUTICS INC273,243$60.4Mshares
JAZZ PHARMACEUTICALS PLCJAZZ PHARMACEUTICALS PLC170,000$28.9Mcall
HROWHARROW INC509,700$25Mcall
SLNOSOLENO THERAPEUTICS INC528,900$24.5Mcall
RAPTRAPT THERAPEUTICS INC665,271$22.5Mshares
CRNXCRINETICS PHARMACEUTICALS IN368,500$17.2Mput
OMEROMEROS CORP950,000$16.3Mput
AMGNAMGEN INC45,000$14.7Mshares
CTMXCYTOMX THERAPEUTICS INC.3,172,616$13.5Mshares
CELCCELCUITY INC105,545$10.5Mshares
RAPTRAPT THERAPEUTICS INC290,000$9.82Mcall
OMEROMEROS CORP550,000$9.45Mcall
DXCMDEXCOM INC137,500$9.13Mcall
PTCTPTC THERAPEUTICS INC118,657$9.01Mshares
VTYXVENTYX BIOSCIENCES INC958,704$8.66Mshares
CGONCG ONCOLOGY INC199,473$8.28Mshares
CORTCORCEPT THERAPEUTICS INC236,700$8.24Mput
APLSAPELLIS PHARMACEUTICALS INC325,600$8.18Mcall
NBIXNEUROCRINE BIOSCIENCES INC54,062$7.67Mshares
RVMDREVOLUTION MEDICINES INC95,000$7.57Mcall
MLYSMINERALYS THERAPEUTICS INC200,000$7.26Mshares
NBIXNEUROCRINE BIOSCIENCES INC51,000$7.23Mcall
CORTCORCEPT THERAPEUTICS INC185,593$6.46Mshares
RAREULTRAGENYX PHARMACEUTICAL IN255,100$5.87Mput
RAREULTRAGENYX PHARMACEUTICAL IN250,000$5.75Mcall
CORTCORCEPT THERAPEUTICS INC163,800$5.7Mcall
ADMAADMA BIOLOGICS INC234,854$4.28Mshares
AGIOAGIOS PHARMACEUTICALS INC137,200$3.73Mcall
KRYSKRYSTAL BIOTECH INC14,814$3.65Mshares
TGTXTG THERAPEUTICS INC117,903$3.51Mshares
AQSTAQUESTIVE THERAPEUTICS INC500,000$3.23Mput
AGIOAGIOS PHARMACEUTICALS INC115,489$3.14Mshares
ERASERASCA INC735,396$2.74Mshares
SLDBSOLID BIOSCIENCES INC424,000$2.39Mcall
ALMSALUMIS INC211,100$2.06Mput
APLSAPELLIS PHARMACEUTICALS INC71,747$1.8Mshares
ZBIOZENAS BIOPHARMA INC46,800$1.7Mput
ZBIOZENAS BIOPHARMA INC46,800$1.7Mcall
NAMSNEWAMSTERDAM PHARMA COMPANY45,830$1.61Mshares
GOSSGOSSAMER BIO INC500,000$1.55Mput
GOSSGOSSAMER BIO INC500,000$1.55Mcall
NKTRNEKTAR THERAPEUTICS36,300$1.53Mput
NKTRNEKTAR THERAPEUTICS36,300$1.53Mcall
INSMINSMED INC8,600$1.5Mcall
TVTXTRAVERE THERAPEUTICS INC36,600$1.4Mcall
CPRXCATALYST PHARMACEUTICALS INC57,388$1.34Mshares
MIND MEDICINE MINDMED INCMIND MEDICINE MINDMED INC58,803$787Kshares
AVTXAVALO THERAPEUTICS INC31,106$565Kshares
GPCRSTRUCTURE THERAPEUTICS INC4,824$336Kshares
LYRALYRA THERAPEUTICS INC COM NEW21,161$65.2Kshares
SYBXSYNLOGIC INC COM NEW19,966$22.4Kshares
ANEBANEBULO PHARMACEUTICALS INC17,736$17.9Kshares

How Q1 2026 was built

Available 13F filings of this filer for the quarter and their roles: the base report is the latest original or restatement, NEW HOLDINGS amendments filed after it are added (method).

FilingRoleAmendmentFiledAcceptedIngested
13F-HR 0001420506-26-001165 base2026-05-15acceptance time not in the bulk data set