Affinity Asset Advisors, LLC More: the full row for Affinity Asset Advisors, LLC 4,007,881 $7.01M 0.34% +900,681 13F-HR Timeline Cormorant Asset Management, LP More: the full row for Cormorant Asset Management, LP 3,570,000 $6.25M 0.32% new 13F-HR Timeline SILVERARC CAPITAL MANAGEMENT, LLC in group SILVERARC CAPITAL MANAGEMENT,… More: the full row for SILVERARC CAPITAL MANAGEMENT, LLC 3,520,490 $6.16M 0.69% +3,294,490 13F-HR Timeline Group Vestal Point Capital, LP More: the full row for Vestal Point Capital, LP 2,600,000 $4.55M 0.11% new 13F-HR Timeline VANGUARD GROUP INC group of 4 filers holding More: the full row for VANGUARD GROUP INC 2,390,486 $4.18M +1,079,532 Timeline Frazier Life Sciences Management, L.P. More: the full row for Frazier Life Sciences Management, L.P. 1,953,467 $3.42M 0.07% 0 13F-HR Timeline Ensign Peak Advisors, Inc More: the full row for Ensign Peak Advisors, Inc 1,832,457 $3.21M 0.01% new 13F-HR Timeline Woodline Partners LP More: the full row for Woodline Partners LP 1,776,547 $3.11M 0.01% new 13F-HR Timeline MILLENNIUM MANAGEMENT LLC in group MILLENNIUM MANAGEMENT LLC More: the full row for MILLENNIUM MANAGEMENT LLC 1,651,473 $2.89M <0.01% +101,623 13F-HR Timeline Group CITADEL ADVISORS LLC in group CITADEL ADVISORS LLC More: the full row for CITADEL ADVISORS LLC 1,384,029 $2.42M <0.01% +427,600 13F-HR Timeline Group Balyasny Asset Management L.P. in group Balyasny Asset Management More: the full row for Balyasny Asset Management L.P. 1,170,893 $2.05M <0.01% +159,938 13F-HR Timeline Group BANK OF AMERICA CORP /DE/ in group BANK OF AMERICA CORP /DE/ More: the full row for BANK OF AMERICA CORP /DE/ 1,121,492 $1.96M <0.01% +831,079 13F-HR Timeline Group Ikarian Capital, LLC More: the full row for Ikarian Capital, LLC 957,062 $1.67M 0.27% 0 13F-HR Timeline Sio Capital Management, LLC More: the full row for Sio Capital Management, LLC 904,268 $1.58M 0.27% 0 13F-HR Timeline MARSHALL WACE, LLP in group MARSHALL WACE, LLP More: the full row for MARSHALL WACE, LLP 904,132 $1.58M <0.01% +283,530 13F-HR Timeline Group GEODE CAPITAL MANAGEMENT, LLC in group GEODE CAPITAL MANAGEMENT, LLC More: the full row for GEODE CAPITAL MANAGEMENT, LLC 500,816 $877K <0.01% +113,249 13F-HR Timeline Group Walleye Capital LLC in group Walleye Capital LLC More: the full row for Walleye Capital LLC 500,375 $876K <0.01% +111,821 13F-HR Timeline Group Squarepoint Ops LLC in group Squarepoint Ops LLC More: the full row for Squarepoint Ops LLC 498,872 $873K <0.01% new 13F-HR Timeline Group NOESIS CAPITAL MANGEMENT CORP More: the full row for NOESIS CAPITAL MANGEMENT CORP 405,000 $709K 0.09% +93,500 13F-HR Timeline TWO SIGMA INVESTMENTS, LP in group TWO SIGMA INVESTMENTS, LP More: the full row for TWO SIGMA INVESTMENTS, LP 400,667 $701K <0.01% -8,191 13F-HR Timeline Group Ally Bridge Group (NY) LLC More: the full row for Ally Bridge Group (NY) LLC 390,147 $683K 0.88% new 13F-HR Timeline ADAR1 Capital Management, LLC in group ADAR1 Capital Management, LLC More: the full row for ADAR1 Capital Management, LLC 375,531 $657K 0.03% -94,347 13F-HR Timeline Group Verdad Advisers, LP More: the full row for Verdad Advisers, LP 298,927 $523K 0.5% +242,609 13F-HR Timeline BOOTHBAY FUND MANAGEMENT, LLC More: the full row for BOOTHBAY FUND MANAGEMENT, LLC 254,412 $445K 0.01% 0 13F-HR Timeline BlackRock, Inc. in group BlackRock, Inc. More: the full row for BlackRock, Inc. 242,016 $424K <0.01% +110,801 13F-HR Timeline Group RENAISSANCE TECHNOLOGIES LLC More: the full row for RENAISSANCE TECHNOLOGIES LLC 202,847 $355K <0.01% new 13F-HR Timeline GOLDMAN SACHS GROUP INC in group GOLDMAN SACHS GROUP INC More: the full row for GOLDMAN SACHS GROUP INC 200,455 $351K <0.01% +243 13F-HR Timeline Group STATE STREET CORP in group STATE STREET CORP More: the full row for STATE STREET CORP 170,799 $299K <0.01% +29,600 13F-HR Timeline Group DAFNA Capital Management LLC More: the full row for DAFNA Capital Management LLC 170,053 $298K 0.06% -23,585 13F-HR Timeline NORTHERN TRUST CORP in group NORTHERN TRUST CORP More: the full row for NORTHERN TRUST CORP 111,319 $195K <0.01% +33,995 13F-HR Timeline Group Atom Investors LP More: the full row for Atom Investors LP 101,557 $178K 0.02% new 13F-HR Timeline XTX Topco Ltd in group XTX Topco Ltd More: the full row for XTX Topco Ltd 57,842 $101K <0.01% -4,609 13F-HR Timeline Group Headlands Technologies LLC More: the full row for Headlands Technologies LLC 47,413 $83K 0.01% +36,463 13F-HR Timeline TWO SIGMA SECURITIES, LLC More: the full row for TWO SIGMA SECURITIES, LLC 16,151 $28.3K <0.01% new 13F-HR Timeline Innovative Asset Advisors Group, LLC More: the full row for Innovative Asset Advisors Group, LLC 15,000 $26.2K 0.01% new 13F-HR Timeline Spark Investment Management LLC More: the full row for Spark Investment Management LLC 13,500 $23.6K 0.05% new 13F-HR Timeline Bank of New York Mellon Corp in group Bank of New York Mellon Corp More: the full row for Bank of New York Mellon Corp 10,637 $18.6K <0.01% new 13F-HR Timeline Group JPMORGAN CHASE & CO in group JPMORGAN CHASE & CO More: the full row for JPMORGAN CHASE & CO 5,897 $10.2K <0.01% +5,895 13F-HR Timeline Group BARCLAYS PLC in group BARCLAYS PLC More: the full row for BARCLAYS PLC 3,255 $5.7K <0.01% new 13F-HR Timeline Group UBS Group AG in group UBS Group AG More: the full row for UBS Group AG 501 $877 <0.01% -1,672 13F-HR Timeline Group FMR LLC in group FMR LLC More: the full row for FMR LLC 433 $757 <0.01% new 13F-HR Timeline Group Fortitude Family Office, LLC More: the full row for Fortitude Family Office, LLC 431 $754 <0.01% -207 13F-HR Timeline OSAIC HOLDINGS, INC. in group OSAIC HOLDINGS, INC. More: the full row for OSAIC HOLDINGS, INC. 380 $665 <0.01% -204 13F-HR Timeline Group WELLS FARGO & COMPANY/MN in group WELLS FARGO & COMPANY/MN More: the full row for WELLS FARGO & COMPANY/MN 101 $177 <0.01% +100 13F-HR Timeline Group SHP Wealth Management More: the full row for SHP Wealth Management 60 $105 <0.01% 0 13F-HR Timeline SBI Securities Co., Ltd. More: the full row for SBI Securities Co., Ltd. 42 $74 <0.01% +20 13F-HR Timeline SOA Wealth Advisors, LLC. More: the full row for SOA Wealth Advisors, LLC. 13 $23 <0.01% 0 13F-HR Timeline MORGAN STANLEY in group MORGAN STANLEY More: the full row for MORGAN STANLEY 10 $18 <0.01% -30,927 13F-HR Timeline Group Caitong International Asset Management … More: the full row for Caitong International Asset Management Co., Ltd 9 $16 <0.01% +7 13F-HR Timeline Activest Wealth Management More: the full row for Activest Wealth Management 4 $7 <0.01% 0 13F-HR Timeline BNP PARIBAS FINANCIAL MARKETS in group BNP PARIBAS FINANCIAL MARKETS More: the full row for BNP PARIBAS FINANCIAL MARKETS 2 $4 <0.01% -3 13F-HR Timeline Group Financial Gravity Companies, Inc. in group Financial Gravity Companies, … More: the full row for Financial Gravity Companies, Inc. 2 $4 <0.01% 13F-HR Timeline Group Rockefeller Capital Management L.P. in group Rockefeller Capital Managemen… More: the full row for Rockefeller Capital Management L.P. 1 $2 <0.01% new 13F-HR Timeline Group