TCG Crossover Management, LLC More: the full row for TCG Crossover Management, LLC 1,473,101 $38.2M 0.92% 0 13F-HR Timeline Boxer Capital Management, LLC More: the full row for Boxer Capital Management, LLC 1,105,683 $27M 2.03% +339,365 13F-HR Timeline MILLENNIUM MANAGEMENT LLC in group MILLENNIUM MANAGEMENT LLC More: the full row for MILLENNIUM MANAGEMENT LLC 683,079 $17.7M 0.01% -48,059 13F-HR Timeline Group Point72 Asset Management, L.P. in group Point72 Asset Management, L.P. More: the full row for Point72 Asset Management, L.P. 664,272 $17.2M 0.03% new 13F-HR Timeline Group Venrock Adviser, LLC More: the full row for Venrock Adviser, LLC 632,931 $16.4M 0.5% 0 13F-HR Timeline STEMPOINT CAPITAL LP More: the full row for STEMPOINT CAPITAL LP 602,798 $13.8M 2.39% +77,159 13F-HR Timeline VANGUARD GROUP INC group of 4 filers holding More: the full row for VANGUARD GROUP INC 505,721 $13.1M +298,669 Timeline PERCEPTIVE ADVISORS LLC in group PERCEPTIVE ADVISORS LLC More: the full row for PERCEPTIVE ADVISORS LLC 503,985 $13.1M 0.2% +274,592 13F-HR Timeline Group Spruce Street Capital LP More: the full row for Spruce Street Capital LP 432,040 $11.2M 2.2% 0 13F-HR Timeline BlackRock, Inc. in group BlackRock, Inc. More: the full row for BlackRock, Inc. 394,864 $10.2M <0.01% +367,013 13F-HR Timeline Group BRAIDWELL LP More: the full row for BRAIDWELL LP 390,753 $10.1M 0.38% -5,347 13F-HR Timeline Kalehua Capital Management LLC More: the full row for Kalehua Capital Management LLC 385,178 $10M 5.75% 0 13F-HR/A Timeline Vestal Point Capital, LP More: the full row for Vestal Point Capital, LP 304,669 $7.91M 0.18% -33,942 13F-HR Timeline 5AM Venture Management, LLC More: the full row for 5AM Venture Management, LLC 271,250 $7.04M 2.44% -116,250 13F-HR Timeline Vivo Capital, LLC More: the full row for Vivo Capital, LLC 260,000 $6.75M 0.62% 0 13F-HR Timeline Balyasny Asset Management L.P. in group Balyasny Asset Management More: the full row for Balyasny Asset Management L.P. 205,032 $5.32M 0.01% +1,144 13F-HR Timeline Group GEODE CAPITAL MANAGEMENT, LLC in group GEODE CAPITAL MANAGEMENT, LLC More: the full row for GEODE CAPITAL MANAGEMENT, LLC 201,652 $5.23M <0.01% +135,803 13F-HR Timeline Group ACUTA CAPITAL PARTNERS, LLC More: the full row for ACUTA CAPITAL PARTNERS, LLC 173,395 $4.5M 3.14% +548 13F-HR Timeline REGENTS OF THE UNIVERSITY OF CALIFORNIA More: the full row for REGENTS OF THE UNIVERSITY OF CALIFORNIA 133,207 $3.46M 0.08% 0 13F-HR Timeline STATE STREET CORP in group STATE STREET CORP More: the full row for STATE STREET CORP 133,084 $3.45M <0.01% +105,358 13F-HR Timeline Group GOLDMAN SACHS GROUP INC in group GOLDMAN SACHS GROUP INC More: the full row for GOLDMAN SACHS GROUP INC 113,531 $2.95M <0.01% +87,680 13F-HR Timeline Group ADAGE CAPITAL PARTNERS GP, L.L.C. in group ADAGE CAPITAL PARTNERS GP, L.… More: the full row for ADAGE CAPITAL PARTNERS GP, L.L.C. 88,653 $2.3M <0.01% 0 13F-HR Timeline Group Euclidean Capital LLC More: the full row for Euclidean Capital LLC 87,696 $2.28M 0.52% 0 13F-HR Timeline TWO SIGMA INVESTMENTS, LP in group TWO SIGMA INVESTMENTS, LP More: the full row for TWO SIGMA INVESTMENTS, LP 71,119 $1.85M <0.01% +31,637 13F-HR Timeline Group NORTHERN TRUST CORP in group NORTHERN TRUST CORP More: the full row for NORTHERN TRUST CORP 63,609 $1.65M <0.01% +51,344 13F-HR Timeline Group ArrowMark Colorado Holdings LLC More: the full row for ArrowMark Colorado Holdings LLC 55,123 $1.43M 0.06% 0 13F-HR Timeline Eversept Partners, LP More: the full row for Eversept Partners, LP 47,777 $1.24M 0.07% -10,847 13F-HR Timeline Walleye Capital LLC in group Walleye Capital LLC More: the full row for Walleye Capital LLC 38,832 $1.01M <0.01% new 13F-HR Timeline Group Ellsworth Advisors, LLC More: the full row for Ellsworth Advisors, LLC 39,283 $856K 0.14% new 13F-HR Timeline BANK OF AMERICA CORP /DE/ in group BANK OF AMERICA CORP /DE/ More: the full row for BANK OF AMERICA CORP /DE/ 31,295 $812K <0.01% new 13F-HR Timeline Group UBS Group AG in group UBS Group AG More: the full row for UBS Group AG 29,229 $758K <0.01% +7,982 13F-HR Timeline Group PRICE T ROWE ASSOCIATES INC /MD/ More: the full row for PRICE T ROWE ASSOCIATES INC /MD/ 27,741 $721K <0.01% +6,026 13F-HR Timeline FRED ALGER MANAGEMENT, LLC in group FRED ALGER MANAGEMENT, LLC More: the full row for FRED ALGER MANAGEMENT, LLC 24,004 $623K <0.01% -47,693 13F-HR Timeline Group XTX Topco Ltd in group XTX Topco Ltd More: the full row for XTX Topco Ltd 16,828 $437K 0.01% new 13F-HR Timeline Group CHARLES SCHWAB INVESTMENT MANAGEMENT INC in group Charles Schwab Trust Co More: the full row for CHARLES SCHWAB INVESTMENT MANAGEMENT INC 16,297 $423K <0.01% new 13F-HR Timeline Group Bank of New York Mellon Corp in group Bank of New York Mellon Corp More: the full row for Bank of New York Mellon Corp 15,379 $399K <0.01% new 13F-HR Timeline Group LMR Partners LLP in group LMR Partners LLP More: the full row for LMR Partners LLP 13,557 $352K <0.01% -10,000 13F-HR Timeline Group RENAISSANCE TECHNOLOGIES LLC More: the full row for RENAISSANCE TECHNOLOGIES LLC 12,374 $321K <0.01% -36,752 13F-HR Timeline Alyeska Investment Group, L.P. in group Alyeska Investment Group, L.P. More: the full row for Alyeska Investment Group, L.P. 10,188 $264K <0.01% 0 13F-HR Timeline Group Fisher Asset Management, LLC More: the full row for Fisher Asset Management, LLC 9,840 $255K <0.01% new 13F-HR Timeline Nuveen, LLC in group TIAA More: the full row for Nuveen, LLC 9,780 $254K <0.01% new 13F-HR Timeline Group RHUMBLINE ADVISERS More: the full row for RHUMBLINE ADVISERS 8,130 $211K <0.01% new 13F-HR Timeline BNP PARIBAS FINANCIAL MARKETS in group BNP PARIBAS FINANCIAL MARKETS More: the full row for BNP PARIBAS FINANCIAL MARKETS 8,029 $208K <0.01% +704 13F-HR Timeline Group DEUTSCHE BANK AG\ in group DEUTSCHE BANK AG\ More: the full row for DEUTSCHE BANK AG\ 7,302 $189K <0.01% new 13F-HR Timeline Group MORGAN STANLEY in group MORGAN STANLEY More: the full row for MORGAN STANLEY 7,151 $186K <0.01% -15,295 13F-HR Timeline Group WELLS FARGO & COMPANY/MN in group WELLS FARGO & COMPANY/MN More: the full row for WELLS FARGO & COMPANY/MN 6,698 $174K <0.01% new 13F-HR Timeline Group MetLife Investment Management, LLC in group MetLife Investment Management… More: the full row for MetLife Investment Management, LLC 4,699 $122K <0.01% new 13F-HR Timeline Group NEW YORK STATE COMMON RETIREMENT FUND More: the full row for NEW YORK STATE COMMON RETIREMENT FUND 4,100 $106K <0.01% new 13F-HR Timeline China Universal Asset Management Co., L… More: the full row for China Universal Asset Management Co., Ltd. 3,650 $94.7K 0.01% +1,150 13F-HR Timeline CITIGROUP INC in group CITIGROUP INC More: the full row for CITIGROUP INC 3,455 $89.7K <0.01% new 13F-HR Timeline Group MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. in group Mirae Asset Global Investment… More: the full row for MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 3,381 $87.7K <0.01% new 13F-HR Timeline Group JPMORGAN CHASE & CO in group JPMORGAN CHASE & CO More: the full row for JPMORGAN CHASE & CO 3,044 $78.3K <0.01% +1,925 13F-HR Timeline Group Police & Firemen's Retirement System of… More: the full row for Police & Firemen's Retirement System of New Jersey 2,166 $56.2K <0.01% new 13F-HR Timeline BARCLAYS PLC in group BARCLAYS PLC More: the full row for BARCLAYS PLC 1,767 $45.9K <0.01% -121 13F-HR Timeline Group ACADIAN ASSET MANAGEMENT LLC in group ACADIAN ASSET MANAGEMENT LLC More: the full row for ACADIAN ASSET MANAGEMENT LLC 1,508 $39K <0.01% 0 13F-HR Timeline Group STRS OHIO More: the full row for STRS OHIO 1,400 $36.3K <0.01% new 13F-HR Timeline Legal & General Group Plc in group Legal & General Group Plc More: the full row for Legal & General Group Plc 715 $18.6K <0.01% new 13F-HR Timeline Group Ameritas Investment Partners, Inc. in group Ameritas Investment Partners,… More: the full row for Ameritas Investment Partners, Inc. 666 $17.3K <0.01% new 13F-HR Timeline Group Russell Investments Group, Ltd. in group Russell Investments Group, Lt… More: the full row for Russell Investments Group, Ltd. 587 $15.2K <0.01% new 13F-HR Timeline Group Tower Research Capital LLC (TRC) in group Tower Research Capital LLC (T… More: the full row for Tower Research Capital LLC (TRC) 428 $11.1K <0.01% +427 13F-HR Timeline Group FMR LLC in group FMR LLC More: the full row for FMR LLC 348 $9.03K <0.01% new 13F-HR Timeline Group ROYAL BANK OF CANADA in group ROYAL BANK OF CANADA More: the full row for ROYAL BANK OF CANADA 311 $8K <0.01% -314 13F-HR Timeline Group State of Wyoming More: the full row for State of Wyoming 212 $5.5K <0.01% new 13F-HR Timeline CALIFORNIA STATE TEACHERS RETIREMENT SY… More: the full row for CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 101 $2.62K <0.01% new 13F-HR/A Timeline Sterling Capital Management LLC More: the full row for Sterling Capital Management LLC 26 $675 <0.01% new 13F-HR Timeline Caitong International Asset Management … More: the full row for Caitong International Asset Management Co., Ltd 1 $26 <0.01% new 13F-HR Timeline