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Disclosery

KRYS KRYSTAL BIOTECH INC

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Stock (common), issuer CIK 1711279

410 managers (423 13F filers) reported a position in KRYS shares at 2026-06-30, 30,289,519 shares in all. 88 filers opened a position and 36 filers sold out during the quarter.

Managers
410
13F filers
423
New
88
Added
176
Reduced
109
Sold out
36
Shares held by filers
30,289,519

Shares held by filers adds up every 13F filer's report, so a share reported by a parent and by its subsidiary counts twice (H9). Managers counts each filer group once.

13D and 13G filers

No 13D or 13G on this security in the data. Structured 13D/G data starts 2024-12-18.

Insider trades

No Form 4 transaction on this security in the data.

13F holders, Q2 2026

Filers in the available 13F reports with a share position at 2026-06-30, filer groups collapsed to one row (method), largest first. Options and principal amounts are left out. A group row states no % of portfolio, since each member reports its own portfolio: the members' percents are listed under it. A value about 1,000 times or 1/1,000 of the price other filers imply is shown as filed but neither ranks the row nor enters a sum.

HolderSharesValue% of portfolioChangeSource
FMR LLCin group FMR LLC4,418,197$1.64B0.07%+44,21013F-HRTimelineGroup
BlackRock, Inc.in group BlackRock, Inc.4,181,432$1.55B0.02%+240,97613F-HRTimelineGroup
VANGUARD GROUP INCgroup of 7 filers holding3,047,073$1.13B+205,622Timeline
Avoro Capital Advisors LLC2,888,888$1.07B9.64%013F-HRTimeline
STATE STREET CORPin group STATE STREET CORP1,351,158$502M0.01%+36,72413F-HRTimelineGroup
Soleus Capital Management, L.P.939,254$349M12.03%-213,83313F-HRTimeline
Capital World Investors777,843$289M0.03%-46,87713F-HRTimeline
GEODE CAPITAL MANAGEMENT, LLCin group GEODE CAPITAL MANAGEMENT, LLC698,993$260M0.01%+55,01813F-HRTimelineGroup
PRICE T ROWE ASSOCIATES INC /MD/687,400$255M0.03%+202,32613F-HRTimeline
Hood River Capital Management LLC663,375$247M1.79%+43,78913F-HRTimeline
Redmile Group, LLCin group Redmile Group, LLC632,005$235M15.77%-41,50013F-HRTimelineGroup
WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC570,153$212M0.64%+162,97513F-HRTimeline
Frazier Life Sciences Management, L.P.481,307$179M3.9%013F-HRTimeline
DIMENSIONAL FUND ADVISORS LPin group DIMENSIONAL FUND ADVISORS LP476,038$177M0.03%+7,04813F-HRTimelineGroup
FIRST TRUST ADVISORS LPin group FIRST TRUST ADVISORS LP324,900$121M0.07%-25,62113F-HRTimelineGroup
Invesco Ltd.in group Invesco Ltd.324,755$121M0.01%+73,38213F-HRTimelineGroup
GOLDMAN SACHS GROUP INCin group GOLDMAN SACHS GROUP INC298,841$111M0.01%+83,89213F-HRTimelineGroup
NORTHERN TRUST CORPin group NORTHERN TRUST CORP283,784$105M0.01%+31,32113F-HRTimelineGroup
FRANKLIN RESOURCES INCin group Franklin Resources261,917$97.3M0.02%+82,65213F-HRTimelineGroup
NORGES BANK259,030$96.3M0.01%new13F-HRTimeline
Jupiter Topco LLCin group Janus Henderson256,665$95.4M0.04%13F-HRTimelineGroup
BANK OF AMERICA CORP /DE/in group BANK OF AMERICA CORP /DE/256,431$95.3M0.01%-4,21613F-HRTimelineGroup
CHARLES SCHWAB INVESTMENT MANAGEMENT INCin group Charles Schwab Trust Co254,828$94.7M0.01%+12,84213F-HRTimelineGroup
MORGAN STANLEYin group MORGAN STANLEY235,491$87.5M<0.01%+26,40913F-HRTimelineGroup
VESTOR CAPITAL, LLC700,914$78.2M4.92%+700,71413F-HRTimeline
UBS Group AGgroup of 2 filers holding187,013$69.5M+6,551Timeline
PRINCIPAL FINANCIAL GROUP INCin group PRINCIPAL FINANCIAL GROUP INC169,550$63M0.03%+7,48013F-HRTimelineGroup
Bank of New York Mellon Corpin group Bank of New York Mellon Corp163,610$60.8M0.01%+14,30313F-HRTimelineGroup
RAYMOND JAMES FINANCIAL INCin group RAYMOND JAMES FINANCIAL INC158,675$59M0.02%+2,61113F-HRTimelineGroup
Woodline Partners LP150,616$56M0.17%013F-HRTimeline
Nuveen, LLCin group TIAA146,520$54.5M0.01%+3,15213F-HRTimelineGroup
BRAIDWELL LP128,975$47.9M1.77%-53,45013F-HRTimeline
VOYA INVESTMENT MANAGEMENT LLCin group VOYA INVESTMENT MANAGEMENT LLC124,442$46.3M0.04%+16,04513F-HRTimelineGroup
TimesSquare Capital Management, LLC111,545$41.5M0.61%-79713F-HRTimeline
Pictet Asset Management Holding SAin group Pictet Asset Management Holdi…107,798$40.1M0.04%-2,86713F-HRTimelineGroup
Public Sector Pension Investment Board105,515$39.2M0.1%+13,22913F-HR/ATimeline
1832 Asset Management L.P.99,300$36.9M0.05%+56,70013F-HRTimeline
WESTFIELD CAPITAL MANAGEMENT CO LP98,707$36.7M0.12%new13F-HRTimeline
BNP PARIBAS FINANCIAL MARKETSin group BNP PARIBAS FINANCIAL MARKETS92,234$34.3M0.02%-79713F-HRTimelineGroup
Handelsbanken Fonder AB90,407$33.6M0.1%-99313F-HRTimeline
JPMORGAN CHASE & COin group JPMORGAN CHASE & CO87,342$33.5M<0.01%-11,76313F-HRTimelineGroup
ORBIMED ADVISORS LLCin group ORBIMED ADVISORS LLC83,200$30.9M0.59%+14,10013F-HRTimelineGroup
S SQUARED TECHNOLOGY, LLC77,545$28.8M8.94%-8,67013F-HRTimeline
Bellevue Group AGin group Bellevue Group AG77,530$28.8M0.61%-404,25513F-HRTimelineGroup
Biondo Investment Advisors, LLC70,945$26.4M3.23%-1,10013F-HRTimeline
SEGALL BRYANT & HAMILL, LLC65,211$24.2M0.29%-14,28613F-HRTimeline
RHUMBLINE ADVISERS61,236$22.8M0.02%-6,86313F-HRTimeline
RENAISSANCE TECHNOLOGIES LLC59,680$22.2M0.03%+50,08013F-HRTimeline
Legal & General Group Plcin group Legal & General Group Plc58,580$21.8M<0.01%-47013F-HRTimelineGroup
C WorldWide Group Holding A/Sin group C WorldWide Group Holding A/S57,809$21.5M0.52%-10,00013F-HRTimelineGroup
CITIGROUP INCin group CITIGROUP INC56,016$20.8M0.01%+24,84413F-HRTimelineGroup
Bridgewater Associates, LP54,489$20.3M0.08%+8,12213F-HRTimeline
SEI INVESTMENTS COin group SEI INVESTMENTS CO54,040$20.1M0.02%+7,47013F-HRTimelineGroup
Russell Investments Group, Ltd.in group Russell Investments Group, Lt…52,621$19.6M0.02%+26,41113F-HRTimelineGroup
Allspring Global Investments Holdings, …in group Allspring Global Investments …52,407$19.5M0.03%+49,93213F-HRTimelineGroup
NEUBERGER BERMAN GROUP LLCin group NEUBERGER BERMAN GROUP LLC51,876$19.3M0.01%+18,79213F-HRTimelineGroup
AMERIPRISE FINANCIAL INCin group AMERIPRISE FINANCIAL INC48,790$18.1M<0.01%-1,04713F-HRTimelineGroup
Palisades Investment Partners, LLC47,801$17.8M5.05%+2,39613F-HRTimeline
ACT CAPITAL MANAGEMENT, LLC45,000$16.7M10.93%-15,47713F-HRTimeline
VICTORY CAPITAL MANAGEMENT INC44,935$16.7M0.01%+4,22013F-HRTimeline
FEDERATED HERMES, INC.in group FEDERATED HERMES, INC.43,848$16.3M0.02%+8,35313F-HRTimelineGroup
Swiss National Bank41,360$15.4M0.01%-1,64013F-HRTimeline
GILDER GAGNON HOWE & CO LLC40,296$15M0.15%+16813F-HRTimeline
CONGRESS ASSET MANAGEMENT CO40,134$14.9M0.09%new13F-HRTimeline
SEB Asset Management AB37,731$14M0.05%-8,61213F-HRTimeline
WELLINGTON MANAGEMENT GROUP LLPin group WELLINGTON MANAGEMENT GROUP L…36,936$13.7M<0.01%+26,70913F-HRTimelineGroup
Life Cycle Investment Partners Ltd35,124$13.1M0.06%new13F-HRTimeline
WELLS FARGO & COMPANY/MNin group WELLS FARGO & COMPANY/MN34,502$12.8M<0.01%+19,51413F-HRTimelineGroup
NEW YORK STATE COMMON RETIREMENT FUND34,033$12.6M0.02%+2,69113F-HRTimeline
Granite Investment Partners, LLC32,837$12.2M0.63%+8,55313F-HRTimeline
PRUDENTIAL FINANCIAL INCin group PRUDENTIAL FINANCIAL INC32,662$12.1M0.01%+3,02413F-HRTimelineGroup
MUTUAL OF AMERICA CAPITAL MANAGEMENT LLCin group MUTUAL OF AMERICA CAPITAL MAN…31,998$11.9M0.12%-3,86113F-HRTimelineGroup
DEUTSCHE BANK AG\in group DEUTSCHE BANK AG\31,836$11.8M<0.01%+7,00513F-HRTimelineGroup
Corient Private Wealth LPin group Corient Private Wealth LP30,558$11.4M0.02%+27,03513F-HR/ATimelineGroup
Fisher Asset Management, LLC27,676$10.3M<0.01%-10813F-HRTimeline
MANUFACTURERS LIFE INSURANCE COMPANY, T…in group MANUFACTURERS LIFE INSURANCE …25,867$9.61M0.01%-10,20213F-HRTimelineGroup
Aberdeen Group plcin group Aberdeen Group plc25,141$9.34M0.01%-5,01413F-HRTimelineGroup
Atle Fund Management AB24,019$8.93M2.4%-13,56013F-HRTimeline
CALIFORNIA STATE TEACHERS RETIREMENT SY…23,692$8.81M0.01%-2,49413F-HR/ATimeline
ALLIANCEBERNSTEIN L.P.34,039$8.79M<0.01%+2,11013F-HRTimeline
TD Asset Management Inc22,712$8.44M0.01%-20,60613F-HRTimeline
Elmind Capital, LP22,000$8.18M2.05%013F-HRTimeline
CANADA LIFE ASSURANCE Coin group CANADA LIFE ASSURANCE Co21,711$8.06M0.01%+29813F-HRTimelineGroup
Creative Planningin group Creative Planning20,318$7.55M<0.01%+4,38113F-HRTimelineGroup
BESSEMER GROUP INCin group BESSEMER GROUP INC20,285$7.54M0.01%013F-HRTimelineGroup
Pinnacle Financial Partners, Inc.in group Pinnacle Financial Partners, …20,243$7.52M0.05%+6313F-HRTimelineGroup
Tetragon Partners GP Ltdin group Tetragon Partners GP Ltd19,668$7.31M1.19%013F-HRTimelineGroup
Lisanti Capital Growth, LLC19,050$7.08M1.56%+53513F-HRTimeline
GW&K Investment Management, LLC18,295$6.8M0.05%-95013F-HRTimeline
Thrivent Financial for Lutheransin group Thrivent Financial for Luther…17,229$6.4M0.01%+313F-HRTimelineGroup
VAN ECK ASSOCIATES CORPin group VAN ECK ASSOCIATES CORP17,071$6.34M<0.01%new13F-HRTimelineGroup
NEW YORK STATE TEACHERS RETIREMENT SYST…16,801$6.24M0.01%+1,16413F-HRTimeline
Mirae Asset Global Investments Co., Ltd.group of 2 filers holding16,615$6.18M-31Timeline
ADAR1 Capital Management, LLCin group ADAR1 Capital Management, LLC16,420$6.1M0.29%-3,59413F-HRTimelineGroup
Cinctive Capital Management LP16,367$6.08M0.24%+13,49313F-HRTimeline
Rhenman & Partners Asset Management AB16,325$6.07M0.57%-35013F-HRTimeline
Informed Momentum Co LLC16,227$6.03M0.54%-25613F-HRTimeline
Mediolanum International Funds Ltd15,940$6.03M0.05%new13F-HRTimeline
CASTLEARK MANAGEMENT LLC16,150$6M0.16%-15,48013F-HRTimeline
SG Americas Securities, LLC16,147$6M<0.01%+10,24813F-HRTimeline
WCM INVESTMENT MANAGEMENT, LLC15,753$5.96M0.01%new13F-HRTimeline
CIM, LLC15,703$5.84M0.75%+71313F-HRTimeline
EFG International AGin group EFG International AG15,304$5.69M0.1%-4,74513F-HRTimelineGroup
MetLife Investment Management, LLCin group MetLife Investment Management…15,196$5.65M0.03%+1,65413F-HRTimelineGroup
STATE BOARD OF ADMINISTRATION OF FLORID…14,483$5.38M0.01%-1,27313F-HRTimeline
Fiera Capital Corpin group Fiera Capital Corp14,251$5.3M0.02%-9,89513F-HRTimelineGroup
AQR CAPITAL MANAGEMENT LLCin group AQR CAPITAL MANAGEMENT LLC14,002$5.2M<0.01%-11213F-HRTimelineGroup
Natixis Investment Managersgroup of 2 filers holding13,649$5.07M-212Timeline
Illinois Municipal Retirement Fund13,455$5M0.06%-69613F-HRTimeline
State of Alaska, Department of Revenue13,385$4.97M0.05%-4,09913F-HRTimeline
ENVESTNET ASSET MANAGEMENT INCin group ENVESTNET ASSET MANAGEMENT INC13,212$4.91M<0.01%+1,22913F-HRTimelineGroup
KORNITZER CAPITAL MANAGEMENT INC /KS13,126$4.88M0.1%new13F-HRTimeline
STATE OF WISCONSIN INVESTMENT BOARD12,998$4.83M0.01%-7,69313F-HRTimeline
CREDIT AGRICOLE S Ain group CREDIT AGRICOLE S A12,976$4.82M0.01%013F-HRTimelineGroup
NOMURA ASSET MANAGEMENT CO LTDgroup of 2 filers holding12,642$4.7M+2,424Timeline
Torray Investment Partners LLC12,156$4.52M0.61%+12413F-HRTimeline
COMMONWEALTH EQUITY SERVICES, LLC12,116$4.5M0.01%+52513F-HRTimeline
Bridge City Capital, LLC11,816$4.39M1%-22913F-HRTimeline
Louisiana State Employees Retirement Sy…11,500$4.27M0.06%+10013F-HR/ATimeline
Privium Fund Management B.V.11,170$4.15M0.76%013F-HRTimeline
BROWN CAPITAL MANAGEMENT LLC10,968$4.08M0.81%+1,72113F-HRTimeline
INTECH INVESTMENT MANAGEMENT LLC10,525$3.91M0.04%-2,99513F-HRTimeline
OSAIC HOLDINGS, INC.in group OSAIC HOLDINGS, INC.10,498$3.9M<0.01%+10,07513F-HRTimelineGroup
VIRGINIA RETIREMENT SYSTEMS ET Al10,400$3.87M0.02%+90013F-HRTimeline
PALISADE CAPITAL MANAGEMENT, LP10,065$3.74M0.16%new13F-HRTimeline
State of Tennessee, Department of Treas…9,845$3.66M0.01%-40913F-HRTimeline
HSBC HOLDINGS PLCin group HSBC HOLDINGS PLC9,598$3.65M<0.01%new13F-HRTimelineGroup
Odyssean, LLC9,349$3.47M0.57%+4,53013F-HRTimeline
CLOUGH CAPITAL PARTNERS L Pin group CLOUGH CAPITAL PARTNERS L P9,257$3.44M0.28%+75513F-HRTimelineGroup
KENNEDY CAPITAL MANAGEMENT LLC9,034$3.36M0.06%+4,13013F-HRTimeline
Erste Asset Management GmbHin group Erste Asset Management GmbH8,700$3.29M0.03%013F-HRTimelineGroup
Rafferty Asset Management, LLC8,836$3.28M0.01%-8,85113F-HRTimeline
Legato Capital Management LLC8,713$3.24M0.27%+1,74013F-HRTimeline
Cetera Investment Advisers8,361$3.11M<0.01%+2,15513F-HRTimeline
Evolutionary Tree Capital Management, L…8,301$3.09M5.82%-4,01313F-HRTimeline
Police & Firemen's Retirement System of…7,709$2.87M0.02%+96213F-HRTimeline
FIFTH THIRD BANK, NATIONAL ASSOCIATIONgroup of 2 filers holding7,630$2.84M+686Timeline
TEALWOOD ASSET MANAGEMENT INC7,561$2.81M1.08%-10313F-HRTimeline
Zurcher Kantonalbank (Zurich Cantonalba…7,452$2.77M0.01%+2,31313F-HRTimeline
BARCLAYS PLCin group BARCLAYS PLC7,436$2.76M<0.01%+2,46713F-HRTimelineGroup
MARTINGALE ASSET MANAGEMENT L P7,311$2.72M0.06%+10313F-HRTimeline
YOUSIF CAPITAL MANAGEMENT, LLC7,192$2.67M0.03%+6113F-HRTimeline
AMALGAMATED BANK7,045$2.62M0.02%-33413F-HRTimeline
STRS OHIO6,800$2.53M0.01%+40013F-HRTimeline
GUGGENHEIM CAPITAL LLCin group GUGGENHEIM CAPITAL LLC6,720$2.5M0.02%+3,20213F-HRTimelineGroup
State of New Jersey Common Pension Fund…in group State of New Jersey Common Pe…6,662$2.48M0.01%-77113F-HRTimelineGroup
TRANSCEND CAPITAL ADVISORS, LLC6,522$2.42M0.16%+4,01113F-HRTimeline
TEACHERS RETIREMENT SYSTEM OF THE STATE…6,458$2.4M0.02%013F-HRTimeline
COMMONWEALTH OF PENNSYLVANIA PUBLIC SCH…6,222$2.31M0.01%-16013F-HRTimeline
AMERICAN CENTURY COMPANIES INCin group AMERICAN CENTURY COMPANIES INC6,204$2.31M<0.01%+3,48713F-HRTimelineGroup
Quantum Private Wealth, LLC6,119$2.27M0.58%-1,06213F-HRTimeline
TWO SIGMA INVESTMENTS, LPin group TWO SIGMA INVESTMENTS, LP6,084$2.26M<0.01%new13F-HRTimelineGroup
Atika Capital Management LLCin group Atika Capital Management LLC6,000$2.23M0.22%-4,62513F-HRTimelineGroup
OREGON PUBLIC EMPLOYEES RETIREMENT FUND5,998$2.23M0.02%+4913F-HRTimeline
PROFUND ADVISORS LLC5,770$2.14M0.06%-3,02013F-HRTimeline
ARIZONA STATE RETIREMENT SYSTEM5,686$2.11M0.01%-28713F-HRTimeline
Homestead Advisers Corp5,500$2.04M0.05%new13F-HRTimeline
FRED ALGER MANAGEMENT, LLCin group FRED ALGER MANAGEMENT, LLC5,418$2.01M0.01%new13F-HRTimelineGroup
Penserra Capital Management LLCin group Penserra Capital Management L…5,142$1.91M0.01%new13F-HRTimelineGroup
USS Investment Management Ltd4,900$1.82M0.01%new13F-HRTimeline
COOKSON PEIRCE & CO INC4,898$1.82M0.06%+20413F-HRTimeline
Cambridge Investment Research Advisors,…4,805$1.79M<0.01%new13F-HR/ATimeline
KLP KAPITALFORVALTNING AS4,800$1.78M0.01%013F-HRTimeline
State of Wyoming4,767$1.77M0.18%new13F-HRTimeline
ProShare Advisors LLC4,760$1.77M<0.01%-41713F-HRTimeline
China Universal Asset Management Co., L…4,692$1.74M0.1%-49513F-HRTimeline
TOTH FINANCIAL ADVISORY CORP4,511$1.68M0.16%+4,50513F-HRTimeline
SUSQUEHANNA INTERNATIONAL GROUP, LLPgroup of 2 filers holding4,394$1.63M-8,752Timeline
Amundiin group Amundi4,368$1.62M<0.01%-1,33813F-HRTimelineGroup
LPL Financial LLC4,317$1.6M<0.01%+2,55213F-HRTimeline
Knights of Columbus Asset Advisors LLC4,175$1.55M0.08%new13F-HRTimeline
Quantinno Capital Management LP4,018$1.49M<0.01%+84713F-HRTimeline
Regal Investment Advisors LLC3,913$1.45M0.08%-13713F-HRTimeline
OMERS ADMINISTRATION Corp3,880$1.44M0.01%-22013F-HRTimeline
Universal- Beteiligungs- und Serviceges…in group Universal- Beteiligungs- und …3,822$1.42M<0.01%-2,40713F-HRTimelineGroup
Maryland State Retirement & Pension Sys…3,816$1.42M0.02%+5213F-HRTimeline
Confluence Wealth Services, Inc.3,792$1.41M0.04%+87013F-HRTimeline
ASSETMARK, INCin group ASSETMARK, INC3,739$1.39M<0.01%+58213F-HRTimelineGroup
Virtus Investment Advisers, LLCin group Virtus Investment Advisers, L…3,657$1.36M0.32%+20813F-HRTimelineGroup
Resona Asset Management Co.,Ltd.in group Resona Asset Management Co.,L…3,387$1.26M0.01%+19313F-HRTimelineGroup
BANK OF MONTREAL /CAN/in group BANK OF MONTREAL /CAN/3,291$1.22M<0.01%+12913F-HRTimelineGroup
HighVista Strategies LLC3,260$1.21M0.28%+1,43613F-HRTimeline
New York Life Investment Management LLCin group New York Life Investment Mana…3,167$1.18M0.01%new13F-HRTimelineGroup
HANSEATIC MANAGEMENT SERVICES INC3,120$1.16M0.85%+12313F-HRTimeline
Ellsworth Advisors, LLC3,268$1.14M0.19%+2313F-HRTimeline
STIFEL FINANCIAL CORPin group STIFEL FINANCIAL CORP2,800$1.04M<0.01%new13F-HRTimelineGroup
CITADEL ADVISORS LLCin group CITADEL ADVISORS LLC2,725$1.01M<0.01%-113F-HRTimelineGroup
Sanctuary Advisors, LLC2,692$1M<0.01%-3,33813F-HRTimeline
Pathstone Holdings, LLCin group Pathstone Holdings, LLC2,672$993K<0.01%+43113F-HRTimelineGroup
PNC Financial Services Group, Inc.in group PNC Financial Services Group,…2,631$978K<0.01%+64613F-HRTimelineGroup
Diversify Advisory Services, LLCgroup of 2 filers holding2,746$966KnewTimeline
XPONANCE LLC2,522$937K0.01%+18313F-HRTimeline
Cornell Pochily Investment Advisors, In…2,515$935K0.25%new13F-HRTimeline
TEACHER RETIREMENT SYSTEM OF TEXAS2,414$897K<0.01%-40913F-HRTimeline
Curi Capital, LLC2,400$892K0.01%new13F-HRTimeline
PIER 88 INVESTMENT PARTNERS LLC2,400$892K0.21%-1,10013F-HRTimeline
BLAIR WILLIAM & CO/IL2,397$891K<0.01%-5113F-HRTimeline
Ameritas Investment Partners, Inc.group of 2 filers holding2,372$882K+316Timeline
PUBLIC EMPLOYEES RETIREMENT ASSOCIATION…2,363$878K<0.01%013F-HRTimeline
Empowered Funds, LLC2,325$864K<0.01%+4913F-HRTimeline