Skip to content
Disclosery

Ikarian Capital, LLC

Follow

13F filer, CIK 1778253, DALLAS, TX

Ikarian Capital, LLC reported $990,387,589 across 169 holdings for the quarter ended 2025-09-30, in a 13F-HR filed 2025-11-14. Its ten largest share positions make up 46.57% of the portfolio.

Filed (acceptance time not in the bulk data set), ingested 13F-HR 0001420506-25-003413

Period
2025-09-30
Reported value
$990M
Holdings
169
Top 10 weight
46.57%
New
72
Sold out
36

Part of the filer group Ikarian Capital, LLC

  • Neil Shahrestani
How groups are built

Stakes and trades reported after 2025-09-30

13D, 13G and Form 4 filings by this filer's group, dated after the 13F period, on securities the quarter does not hold as shares.

  • QNRX QUOIN PHARMACEUTICALS LTD: 13G/A 211,538 shares, 4.4% of the class, 13G/A filed 2026-10-07, 0001778253-26-000004Timeline
    Accepted , ingested

Largest buys vs the previous quarter

SecurityShares changeApprox. value
GMABnew+175,000$53M
ABVXnew+396,098$33.4M
IONSnew+415,163$27.2M
PTCTnew+280,551$17.2M
RAPTnew+615,000$15.9M

Ranked by the share change valued at this quarter's implied price (value over shares in the 13F). A position sold out is valued at the previous quarter's price, its last report.

Largest sells vs the previous quarter

SecurityShares changeApprox. value
INSMreduced-150,000-$21.6M
ALNYexited-56,594-$18.5M
CDTXreduced-186,784-$17.9M
COGTreduced-1,024,248-$14.7M
VERONA PHARMA PLCexited-146,831-$13.9M

Ranked by the share change valued at this quarter's implied price (value over shares in the 13F). A position sold out is valued at the previous quarter's price, its last report.

Holdings, Q3 2025

Share positions as resolved from 13F-HR 0001420506-25-003413, largest first. % of portfolio is the value over $494,311,982, the sum of the share positions whose value is usable for ratios (method).

SecurityHistorySharesValue% of portfolioChangeLatest eventTimeline
GMABGENMAB A/SQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 175,000 shares 175,000$53M10.73%newTimeline
ABVXABIVAX SAQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 396,098 shares 396,098$33.4M6.76%newTimeline
IONSIONIS PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 415,163 shares 415,163$27.2M5.49%newTimeline
CDTXCIDARA THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: 53,940 shares; 2025Q1: 248,940 shares; 2025Q2: 464,488 shares; 2025Q3: 277,704 shares 277,704$26.6M5.38%-186,784Timeline
MAZEMAZE THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: 322,740 shares; 2025Q2: 262,740 shares; 2025Q3: 740,825 shares 740,825$19.2M3.89%+478,085Timeline
PTCTPTC THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 280,551 shares 280,551$17.2M3.48%newTimeline
RAPTRAPT THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 615,000 shares 615,000$15.9M3.21%newTimeline
DNTHDIANTHUS THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 346,001 shares 346,001$13.6M2.75%newTimeline
CYTKCYTOKINETICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 170,147 shares; 2024Q4: 149,982 shares; 2025Q1: 149,982 shares; 2025Q2: 233,464 shares; 2025Q3: 222,674 shares 222,674$12.2M2.48%-10,790Timeline
FULCFULCRUM THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 75,000 shares; 2024Q4: 200,096 shares; 2025Q1: 200,096 shares; 2025Q2: 428,521 shares; 2025Q3: 1,289,225 shares 1,289,225$11.9M2.4%+860,704Timeline
PCVXVAXCYTE INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: 200,000 shares; 2025Q2: 305,000 shares; 2025Q3: 311,682 shares 311,682$11.2M2.27%+6,682Timeline
CTMXCYTOMX THERAPEUTICS INC.Quarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 8,924 shares; 2024Q4: 8,924 shares; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 3,372,616 shares 3,372,616$10.8M2.18%newTimeline
JAZZJAZZ PHARMACEUTICALS PLCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 40,000 shares; 2025Q3: 77,800 shares 77,800$10.3M2.07%+37,800Timeline
APLSAPELLIS PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: 3,594 shares; 2025Q1: 75,000 shares; 2025Q2: 75,000 shares; 2025Q3: 451,902 shares 451,902$10.2M2.07%+376,902Timeline
CGONCG ONCOLOGY INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 155,000 shares; 2025Q3: 249,473 shares 249,473$10M2.03%+94,473Timeline
AKROAKERO THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: 245,000 shares; 2025Q2: 220,000 shares; 2025Q3: 206,854 shares 206,854$9.82M1.99%-13,146Timeline
ZURAZURA BIO LTDQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 2,132,322 shares 2,132,322$9.23M1.87%newTimeline
TENXTENAX THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 967,600 shares 967,600$7.36M1.49%newTimeline
KODKODIAK SCIENCES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 476,586 shares; 2024Q4: 576,166 shares; 2025Q1: 649,534 shares; 2025Q2: 599,534 shares; 2025Q3: 413,841 shares 413,841$6.77M1.37%-185,693Timeline
TGTXTG THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: 291,240 shares; 2025Q1: 210,065 shares; 2025Q2: 209,938 shares; 2025Q3: 174,959 shares 174,959$6.32M1.28%-34,979Timeline
ACOGALPHA COGNITION INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: 755,867 shares; 2025Q1: 967,867 shares; 2025Q2: 917,867 shares; 2025Q3: 946,259 shares 946,259$6.16M1.25%+28,392Timeline
CRNXCRINETICS PHARMACEUTICALS INQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 426,913 shares; 2024Q4: 516,431 shares; 2025Q1: 523,431 shares; 2025Q2: 433,431 shares; 2025Q3: 130,902 shares 130,902$5.45M1.1%-302,529Timeline
VRDNVIRIDIAN THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 499,977 shares; 2024Q4: 469,949 shares; 2025Q1: 494,949 shares; 2025Q2: 469,949 shares; 2025Q3: 245,518 shares 245,518$5.3M1.07%-224,431Timeline
PHVSPHARVARIS N VQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 210,165 shares 210,165$5.24M1.06%newTimeline
SNDXSYNDAX PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 333,733 shares 333,733$5.13M1.04%newTimeline
AGIOAGIOS PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 126,979 shares 126,979$5.1M1.03%newTimeline
DCTHDELCATH SYS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 100,370 shares; 2024Q4: 100,365 shares; 2025Q1: 100,365 shares; 2025Q2: 322,390 shares; 2025Q3: 431,251 shares 431,251$4.64M0.94%+108,861Timeline
GPCRSTRUCTURE THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 115,200 shares; 2024Q4: 284,085 shares; 2025Q1: 264,085 shares; 2025Q2: 183,085 shares; 2025Q3: 163,237 shares 163,237$4.57M0.92%-19,848Timeline
TVTXTRAVERE THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: 22,600 shares; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 190,781 shares 190,781$4.56M0.92%newTimeline
FBRXFORTE BIOSCIENCES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: 609,225 shares; 2025Q1: 609,225 shares; 2025Q2: 476,443 shares; 2025Q3: 300,000 shares 300,000$4.5M0.91%-176,443Timeline
TARSTARSUS PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 1,030,277 shares; 2024Q4: 607,689 shares; 2025Q1: 485,021 shares; 2025Q2: 196,536 shares; 2025Q3: 73,619 shares 73,619$4.38M0.89%-122,917Timeline
KRYSKRYSTAL BIOTECH INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 24,421 shares 24,421$4.31M0.87%newTimeline
ARGXARGENX SEQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 5,942 shares 5,942$4.3M0.87%newTimeline
VTYXVENTYX BIOSCIENCES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 192,647 shares; 2024Q4: 1,092,590 shares; 2025Q1: 1,217,590 shares; 2025Q2: 967,590 shares; 2025Q3: 1,309,604 shares 1,309,604$4.07M0.82%+342,014Timeline
PVLAPALVELLA THERAPEUTICS INC NEQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 64,746 shares 64,746$4.06M0.82%newTimeline
SLNOSOLENO THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 221,437 shares; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 55,946 shares 55,946$3.78M0.77%newTimeline
LXEOLEXEO THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 257,216 shares; 2024Q4: 499,301 shares; 2025Q1: 550,029 shares; 2025Q2: 550,029 shares; 2025Q3: 567,601 shares 567,601$3.77M0.76%+17,572Timeline
LABDDIREXION SHARES ETF TRUSTQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 91,959 shares 91,959$3.72M0.75%newTimeline
RLMDRELMADA THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 40,369 shares; 2024Q4: 40,270 shares; 2025Q1: 40,270 shares; 2025Q2: 40,270 shares; 2025Q3: 1,843,060 shares 1,843,060$3.7M0.75%+1,802,790Timeline
QUREUNIQURE NVQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 119,986 shares; 2025Q3: 58,610 shares 58,610$3.42M0.69%-61,376Timeline
VIRVIR BIOTECHNOLOGY INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: 897,862 shares; 2025Q1: 1,068,062 shares; 2025Q2: 1,068,062 shares; 2025Q3: 593,374 shares 593,374$3.39M0.69%-474,688Timeline
MLTXMOONLAKE IMMUNOTHERAPEUTICSQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 435,839 shares 435,839$3.12M0.63%newTimeline
NAMSNEWAMSTERDAM PHARMA COMPANYQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 206,800 shares; 2025Q3: 106,800 shares 106,800$3.04M0.61%-100,000Timeline
UPBUPSTREAM BIO INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 161,113 shares 161,113$3.03M0.61%newTimeline
GUTSFRACTYL HEALTH INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 1,800,000 shares 1,800,000$2.86M0.58%newTimeline
BBOTBRIDGEBIO ONCOLOGY THERAPEUTQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 245,231 shares 245,231$2.84M0.57%newTimeline
BBIOBRIDGEBIO PHARMA INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 285,613 shares; 2024Q4: 215,713 shares; 2025Q1: 90,837 shares; 2025Q2: not reported; 2025Q3: 51,967 shares 51,967$2.7M0.55%newTimeline
PEPGPEPGEN INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: 150,000 shares; 2025Q2: 150,000 shares; 2025Q3: 535,967 shares 535,967$2.48M0.5%+385,967Timeline
STIMNEURONETICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: 1,100,000 shares; 2025Q2: 1,099,700 shares; 2025Q3: 905,716 shares 905,716$2.47M0.5%-193,984Timeline
RLAYRELAY THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 693,350 shares; 2024Q4: 693,308 shares; 2025Q1: 743,308 shares; 2025Q2: 743,308 shares; 2025Q3: 467,362 shares 467,362$2.44M0.49%-275,946Timeline
ADMAADMA BIOLOGICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 159,854 shares 159,854$2.34M0.47%newTimeline
CPRXCATALYST PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 417,850 shares; 2024Q4: 349,649 shares; 2025Q1: 249,649 shares; 2025Q2: 209,649 shares; 2025Q3: 116,388 shares 116,388$2.29M0.46%-93,261Timeline
IVVDINVIVYD INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 2,078,706 shares 2,078,706$2.29M0.46%newTimeline
ALECALECTOR INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: 950,000 shares; 2025Q1: 950,000 shares; 2025Q2: 900,000 shares; 2025Q3: 760,000 shares 760,000$2.25M0.46%-140,000Timeline
VTGNVISTAGEN THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: 77,616 shares; 2025Q1: 601,703 shares; 2025Q2: 601,703 shares; 2025Q3: 620,869 shares 620,869$2.2M0.45%+19,166Timeline
AVTXAVALO THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 970,359 shares; 2024Q4: 970,259 shares; 2025Q1: 200,000 shares; 2025Q2: 35,300 shares; 2025Q3: 159,777 shares 159,777$2.03M0.41%+124,477Timeline
INSMINSMED INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 154,835 shares; 2024Q4: 119,800 shares; 2025Q1: 84,800 shares; 2025Q2: 163,751 shares; 2025Q3: 13,751 shares 13,751$1.98M0.4%-150,000Timeline
ARVNARVINAS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: 229,900 shares; 2025Q2: 850,000 shares; 2025Q3: 226,257 shares 226,257$1.93M0.39%-623,743Timeline
CAPRCAPRICOR THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 300,000 shares; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 264,642 shares 264,642$1.91M0.39%newTimeline
PRQRPROQR THRAPEUTICS N VQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 483,583 shares; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 868,069 shares; 2025Q3: 892,229 shares 892,229$1.9M0.38%+24,160Timeline
PTHSPELTHOS THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 62,451 shares 62,451$1.75M0.35%newTimeline
CPIXCUMBERLAND PHARMACEUTICALS IQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: 740,000 shares; 2025Q2: 595,932 shares; 2025Q3: 555,932 shares 555,932$1.73M0.35%-40,000Timeline
PRAXPRAXIS PRECISION MEDICINES IQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: 145,502 shares; 2025Q2: 276,950 shares; 2025Q3: 28,571 shares 28,571$1.51M0.31%-248,379Timeline
ANABANAPTYSBIO INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 15,662 shares; 2025Q3: 48,410 shares 48,410$1.48M0.3%+32,748Timeline
DYNDYNE THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: 358,837 shares; 2025Q2: 363,837 shares; 2025Q3: 113,837 shares 113,837$1.44M0.29%-250,000Timeline
OVIDOVID THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 1,095,574 shares 1,095,574$1.42M0.29%newTimeline
JANXJANUX THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: 74,691 shares; 2025Q1: 129,691 shares; 2025Q2: 129,691 shares; 2025Q3: 54,691 shares 54,691$1.34M0.27%-75,000Timeline
SLNSILENCE THERAPEUTICS PLCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 587,343 shares; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 873,568 shares; 2025Q3: 900,784 shares 900,784$1.31M0.26%+27,216Timeline
ZYMEZYMEWORKS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 25,000 shares; 2025Q3: 72,787 shares 72,787$1.24M0.25%+47,787Timeline
TERNTERNS PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 308,497 shares; 2024Q4: 308,491 shares; 2025Q1: 308,491 shares; 2025Q2: 58,491 shares; 2025Q3: 164,202 shares 164,202$1.23M0.25%+105,711Timeline
SLDBSOLID BIOSCIENCES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: 230,000 shares; 2025Q2: not reported; 2025Q3: 176,690 shares 176,690$1.09M0.22%newTimeline
IFRXINFLARX NVQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 704,987 shares; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 705,010 shares; 2025Q3: 722,066 shares 722,066$968K0.2%+17,056Timeline
DRUGBRIGHT MINDS BIOSCIENCES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: 152,211 shares; 2025Q1: 65,431 shares; 2025Q2: 65,431 shares; 2025Q3: 15,431 shares 15,431$936K0.19%-50,000Timeline
SGMOQSANGAMO THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: 1,860,179 shares; 2025Q1: 1,860,179 shares; 2025Q2: 1,260,179 shares; 2025Q3: 1,294,652 shares 1,294,652$872K0.18%+34,473Timeline
MBXMBX BIOSCIENCES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 48,071 shares 48,071$841K0.17%newTimeline
PRMEPRIME MEDICINE INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 150,000 shares 150,000$831K0.17%newTimeline
HELPCYBIN INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 367,195 shares; 2024Q4: 397,175 shares; 2025Q1: 397,175 shares; 2025Q2: 140,475 shares; 2025Q3: 140,475 shares 140,475$827K0.17%0Timeline
IMUXIMMUNIC INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 493,496 shares; 2024Q4: 1,614,170 shares; 2025Q1: 914,170 shares; 2025Q2: 914,170 shares; 2025Q3: 914,170 shares 914,170$806K0.16%0Timeline
MIND MEDICINE MINDMED INCMIND MEDICINE MINDMED INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 62,481 shares; 2024Q4: 62,691 shares; 2025Q1: 62,691 shares; 2025Q2: 62,691 shares; 2025Q3: 62,691 shares 62,691$739K0.15%0
LYELLYELL IMMUNOPHARMA INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 43,799 shares; 2025Q3: 43,799 shares 43,799$711K0.14%0Timeline
WVEWAVE LIFE SCIENCES LTDQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 544,265 shares; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 161,137 shares; 2025Q3: 95,955 shares 95,955$702K0.14%-65,182Timeline
SONNET BIOTHERAPEUTC HLDNG ISONNET BIOTHERAPEUTC HLDNG IQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 150,000 shares 150,000$687K0.14%new
IOBTQIO BIOTECH INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 1,525,893 shares 1,525,893$554K0.11%newTimeline
VERUVERU INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 142,523 shares 142,523$542K0.11%newTimeline
IBIOIBIO INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 600,000 shares; 2024Q4: 599,913 shares; 2025Q1: 599,913 shares; 2025Q2: 599,913 shares; 2025Q3: 617,327 shares 617,327$511K0.1%+17,414Timeline
EQEQUILLIUM INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 332,297 shares 332,297$475K0.1%newTimeline
ABOSACUMEN PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 266,435 shares; 2024Q4: 265,769 shares; 2025Q1: 265,769 shares; 2025Q2: 265,769 shares; 2025Q3: 265,769 shares 265,769$454K0.09%0Timeline
ANROALTO NEUROSCIENCE INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: 350,000 shares; 2025Q1: 175,000 shares; 2025Q2: 110,000 shares; 2025Q3: 110,000 shares 110,000$442K0.09%0Timeline
IMTXIMMATICS N.VQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 49,415 shares; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 49,396 shares; 2025Q3: 49,396 shares 49,396$421K0.09%0Timeline
KZRKEZAR LIFE SCIENCES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: 106,901 shares; 2025Q1: 106,901 shares; 2025Q2: 106,901 shares; 2025Q3: 106,901 shares 106,901$417K0.08%0Timeline
ANEBANEBULO PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 157,862 shares; 2024Q4: 157,720 shares; 2025Q1: 157,720 shares; 2025Q2: 157,720 shares; 2025Q3: 157,720 shares 157,720$394K0.08%0Timeline
EVAXEVAXION ASQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: 80,000 shares; 2025Q2: 80,000 shares; 2025Q3: 80,000 shares 80,000$301K0.06%0Timeline
VKTXVIKING THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: 50,000 shares; 2025Q2: 100,000 shares; 2025Q3: 10,000 shares 10,000$263K0.05%-90,000Timeline
VYGRVOYAGER THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 55,857 shares; 2024Q4: 55,766 shares; 2025Q1: 55,766 shares; 2025Q2: 55,766 shares; 2025Q3: 55,766 shares 55,766$260K0.05%0Timeline
LXRXLEXICON PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: 1,550,000 shares; 2025Q1: 1,417,952 shares; 2025Q2: 176,479 shares; 2025Q3: 176,479 shares 176,479$238K0.05%0Timeline
NYXHNYXOAH S AQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 50,699 shares; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 50,627 shares; 2025Q3: 50,627 shares 50,627$233K0.05%0Timeline
RNACCARTESIAN THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 52,193 shares; 2024Q4: 52,166 shares; 2025Q1: 22,166 shares; 2025Q2: 22,166 shares; 2025Q3: 22,166 shares 22,166$227K0.05%0Timeline
FTHFAETH THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 22,497 shares; 2025Q3: 22,497 shares 22,497$213K0.04%0Timeline
BIOMX INCBIOMX INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 893,000 shares; 2024Q4: 892,976 shares; 2025Q1: 892,976 shares; 2025Q2: 892,976 shares; 2025Q3: 392,976 shares 392,976$206K0.04%-500,000
ARCTARCTURUS THERAPEUTICS HLDGSQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: 200,000 shares; 2025Q1: 175,000 shares; 2025Q2: 175,000 shares; 2025Q3: 10,721 shares 10,721$198K0.04%-164,279Timeline
KPTIKARYOPHARM THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: 27,257 shares; 2025Q2: 27,257 shares; 2025Q3: 27,257 shares 27,257$178K0.04%0Timeline
COGTCOGENT BIOSCIENCES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 1,035,528 shares; 2025Q3: 11,280 shares 11,280$162K0.03%-1,024,248Timeline
AIRSAIRSCULPT TECHNOLOGIES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 17,951 shares; 2025Q3: 17,951 shares 17,951$144K0.03%0Timeline
CMMBCHEMOMAB THERAPEUTICS LTDQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 53,262 shares 53,262$140K0.03%newTimeline
LYRALYRA THERAPEUTICS INC COM NEWQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 21,161 shares; 2025Q3: 21,161 shares 21,161$139K0.03%0Timeline
PMVPPMV PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 97,500 shares 97,500$136K0.03%newTimeline
MGNXMACROGENICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 80,079 shares; 2024Q4: 80,071 shares; 2025Q1: 80,071 shares; 2025Q2: 80,071 shares; 2025Q3: 80,071 shares 80,071$135K0.03%0Timeline
SPRBSPRUCE BIOSCIENCES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 13,332 shares 13,332$119K0.02%newTimeline
AETHLON MED INCAETHLON MED INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 153,659 shares; 2025Q3: 153,659 shares 153,659$115K0.02%0
VYNEVYNE THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 290,000 shares; 2025Q3: 290,000 shares 290,000$97.1K0.02%0Timeline
JSPRJASPER THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 55,175 shares; 2024Q4: 55,107 shares; 2025Q1: 25,107 shares; 2025Q2: 25,107 shares; 2025Q3: 25,107 shares 25,107$59.8K0.01%0Timeline
TRAWTRAWS PHARMA INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: 98,493 shares; 2025Q1: 28,493 shares; 2025Q2: 28,493 shares; 2025Q3: 28,493 shares 28,493$52.7K0.01%0Timeline
TOVXTHERIVA BIOLOGICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: 120,031 shares; 2025Q2: 120,031 shares; 2025Q3: 120,031 shares 120,031$48.6K0.01%0Timeline
SYBXSYNLOGIC INC COM NEWQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 20,448 shares; 2024Q4: 20,422 shares; 2025Q1: 20,422 shares; 2025Q2: 20,422 shares; 2025Q3: 20,422 shares 20,422$34.5K0.01%0Timeline
NMRANEUMORA THERAPEUTICS INC.Quarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: 15,457 shares; 2025Q2: 12,498 shares; 2025Q3: 12,498 shares 12,498$22.7K<0.01%0Timeline
AMIXAUTONOMIX MED INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: 20,000 shares; 2025Q1: 20,000 shares; 2025Q2: 20,000 shares; 2025Q3: 20,000 shares 20,000$21.6K<0.01%0Timeline

Options

Puts and calls, as filed. The amount and value describe the underlying shares, not the option premium, so they stay out of % of portfolio (H5).

SecurityTypeAmountValueChange
UTHRUNITED THERAPEUTICS CORP DEL Stockput209,800$88Mnew
XBISPDR SERIES TRUST S&P BIOTECHput750,000$75.2Mnew
BMYBRISTOL-MYERS SQUIBB CO COMput800,000$36.1Mnew
UNIQURE NVUNIQURE NV CALLcall535,600$31.3M-264,400
SRRKSCHOLAR ROCK HLDG CORP COMcall561,600$20.9M+461,600
INSMINSMED INC Stockput100,000$14.4Mnew
INSMINSMED INC Stockcall100,000$14.4Mnew
HROWHARROW INC COMcall289,700$14Mnew
PTCTPTC THERAPEUTICS INC COMcall213,000$13.1Mnew
BIOHAVEN LTDBIOHAVEN LTD COMcall796,400$12M+496,400
SLNOSOLENO THERAPEUTICS INC COMcall176,100$11.9M-23,900
CRNXCRINETICS PHARMACEUTICALS IN Stockcall257,700$10.7Mnew
JAZZ PHARMACEUTICALS PLCJAZZ PHARMACEUTICALS PLC SHS USDcall70,700$9.32Mnew
NVONOVO-NORDISK A S ADRcall150,000$8.32Mnew
APLSAPELLIS PHARMACEUTICALS INC COMcall358,000$8.1Mnew
CNTACENTESSA PHARMACEUTICALS PLC SPONSORED ADScall307,700$7.46M+107,700
CYTKCYTOKINETICS INC COM NEWcall110,900$6.1M-39,100
AGIOAGIOS PHARMACEUTICALS INC COMcall150,000$6.02Mnew
SPRYARS PHARMACEUTICALS INC COMcall562,400$5.65Mnew
PRAXPRAXIS PRECISION MEDICINES I COM NEWcall100,000$5.3M-142,400
TVTXTRAVERE THERAPEUTICS INC COMcall214,500$5.13Mnew
ANABANAPTYSBIO INC COMput161,100$4.93Mnew
ANABANAPTYSBIO INC COMcall161,100$4.93Mnew
KALVKALVISTA PHARMACEUTICALS INC COMcall400,000$4.87M0
LQDALIQUIDIA CORPORATION Stockcall200,000$4.55Mnew
RAPTRAPT THERAPEUTICS INC COM NEWcall175,000$4.51Mnew
MTSRMETSERA INC COMput86,000$4.5Mnew
MTSRMETSERA INC COMcall86,000$4.5Mnew
RVMDREVOLUTION MEDICINES INC Stockcall95,000$4.44Mnew
MLTXMOONLAKE IMMUNOTHERAPEUTICS Stockcall612,200$4.39M+517,700
ARCTARCTURUS THERAPEUTICS HLDGS COMcall227,200$4.19Mnew
TEVATEVA PHARMACEUTICAL INDS LTD ADRcall200,000$4.04M0
ALTALTIMMUNE INC COM NEWcall1,000,000$3.77M+172,500
SRRKSCHOLAR ROCK HLDG CORP COMput96,200$3.58Mnew
MBXMBX BIOSCIENCES INC Stockput200,000$3.5Mnew
MBXMBX BIOSCIENCES INC Stockcall200,000$3.5Mnew
SLNOSOLENO THERAPEUTICS INC COMput50,000$3.38M-150,000
MLTXMOONLAKE IMMUNOTHERAPEUTICS Stockput450,000$3.23M+255,500
SLDBSOLID BIOSCIENCES INC COMMON STOCKcall468,000$2.89Mnew
RAREULTRAGENYX PHARMACEUTICAL IN COMput92,600$2.79M-207,400
SRPTSAREPTA THERAPEUTICS INC COMcall137,000$2.64M-195,100
CMPSCOMPASS PATHWAYS PLC SPONSORED ADScall400,000$2.29Mnew
AKROAKERO THERAPEUTICS INC COMcall41,600$1.98M-2,800
LRMRLARIMAR THERAPEUTICS INC COMcall548,400$1.77Mnew
PRMEPRIME MEDICINE INC COMput250,000$1.39Mnew
PRMEPRIME MEDICINE INC COMcall250,000$1.39Mnew
UTHRUNITED THERAPEUTICS CORP DEL Stockcall2,300$964Knew
IONSIONIS PHARMACEUTICALS INC Stockcall13,300$870Knew
TVRDTVARDI THERAPEUTICS INC COMcall19,000$740Knew
CAPRCAPRICOR THERAPEUTICS INC COMMON STOCKput100,000$721K-1,260,200
CAPRCAPRICOR THERAPEUTICS INC COMMON STOCKcall100,000$721K-600,000
CRBPCORBUS PHARMACEUTICALS HLDGS COM NEWcall54,800$693Knew
PCVXVAXCYTE INC Stockcall7,000$252K+100

Sold out in Q3 2025

Positions in the previous quarter's report that this quarter's report no longer lists.

SecurityShares beforeValue beforeType
CDTXCIDARA THERAPEUTICS INC501,600$24.4Mput
RAREULTRAGENYX PHARMACEUTICAL IN563,100$20.5Mcall
ALNYALNYLAM PHARMACEUTICALS INC56,594$18.5Mshares
CDTXCIDARA THERAPEUTICS INC321,000$15.6Mcall
VERONA PHARMA PLCVERONA PHARMA PLC146,831$13.9Mshares
APGEAPOGEE THERAPEUTICS INC232,047$10.1Mshares
VKTXVIKING THERAPEUTICS INC350,000$9.28Mcall
SRPTSAREPTA THERAPEUTICS INC449,087$7.68Mshares
FULCFULCRUM THERAPEUTICS INC534,000$3.67Mcall
VERAVERA THERAPEUTICS INC153,200$3.61Mcall
APGEAPOGEE THERAPEUTICS INC79,100$3.44Mput
TECXTECTONIC THERAPEUTIC INC163,696$3.25Mshares
ELDNELEDON PHARMACEUTICALS INC1,000,221$2.71Mshares
BIIBBIOGEN INC21,516$2.7Mshares
GERNGERON CORP1,600,000$2.26Mshares
KALVKALVISTA PHARMACEUTICALS INC198,528$2.24Mshares
MTSRMETSERA INC77,316$2.2Mshares
COGTCOGENT BIOSCIENCES INC262,600$1.89Mcall
SRRKSCHOLAR ROCK HLDG CORP49,179$1.74Mshares
RCUSARCUS BIOSCIENCES INC163,363$1.33Mshares
NUVBNUVATION BIO INC619,258$1.21Mshares
Tourmaline Bio IncTourmaline Bio Inc67,927$1.09Mshares
Veru IncVeru Inc1,425,239$829Kshares
ORKAORUKA THERAPEUTICS INC68,574$769Kshares
IBBISHARES TR5,755$728Kshares
PRTAPROTHENA CORP PLC100,000$607Kcall
INBXINHIBRX BIOSCIENCES INC42,122$601Kshares
KYMRKYMERA THERAPEUTICS INC10,000$436Kput
APGEAPOGEE THERAPEUTICS INC8,400$365Kcall
VERAVERA THERAPEUTICS INC14,096$332Kshares
VIGIL NEUROSCIENCE INCVIGIL NEUROSCIENCE INC31,360$249Kshares
CHEMOMAB THERAPEUTICS LTDCHEMOMAB THERAPEUTICS LTD213,052$247Kshares
SGMTSAGIMET BIOSCIENCES INC11,984$91.3Kshares
SPRUCE BIOSCIENCES INCSPRUCE BIOSCIENCES INC1,000,000$72.5Kshares
TKNOALPHA TEKNOVA INC14,008$68.8Kshares
HOOKHOOKIPA PHARMA INC COM NEW52,996$66.5Kshares

How Q3 2025 was built

Available 13F filings of this filer for the quarter and their roles: the base report is the latest original or restatement, NEW HOLDINGS amendments filed after it are added (method).

FilingRoleAmendmentFiledAcceptedIngested
13F-HR 0001420506-25-003413 base2025-11-14acceptance time not in the bulk data set