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Disclosery

LYEL LYELL IMMUNOPHARMA INC

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Stock (common), issuer CIK 1806952

82 managers (86 13F filers) reported a position in LYEL shares at 2026-06-30, 11,982,386 shares in all. 23 filers opened a position and 9 filers sold out during the quarter.

Managers
82
13F filers
86
New
23
Added
28
Reduced
19
Sold out
9
Shares held by filers
11,982,386

Shares held by filers adds up every 13F filer's report, so a share reported by a parent and by its subsidiary counts twice (H9). Managers counts each filer group once.

13D and 13G filers

No 13D or 13G on this security in the data. Structured 13D/G data starts 2024-12-18.

Insider trades

No Form 4 transaction on this security in the data.

13F holders, Q2 2026

Filers in the available 13F reports with a share position at 2026-06-30, filer groups collapsed to one row (method), largest first. Options and principal amounts are left out. A group row states no % of portfolio, since each member reports its own portfolio: the members' percents are listed under it. A value about 1,000 times or 1/1,000 of the price other filers imply is shown as filed but neither ranks the row nor enters a sum.

HolderSharesValue% of portfolioChangeSource
ARCH Venture Management, LLC3,247,162$45.5M4.14%013F-HRTimeline
GSK plc1,512,659$21.3M3.53%013F-HRTimeline
VANGUARD GROUP INCgroup of 4 filers holding976,925$13.7M+143,665Timeline
Orland Properties Ltdin group Orland Properties Ltd754,698$10.6M5.25%013F-HRTimelineGroup
BlackRock, Inc.in group BlackRock, Inc.724,342$10.2M<0.01%+532,52213F-HRTimelineGroup
Almitas Capital LLC581,407$8.17M1.96%+3,60013F-HRTimeline
Foresite Capital Management VI LLCgroup of 2 filers holding476,386$6.69M-801,091Timeline
MILLENNIUM MANAGEMENT LLCin group MILLENNIUM MANAGEMENT LLC367,473$5.16M<0.01%-91,43213F-HRTimelineGroup
Opaleye Management Inc.344,025$4.83M0.44%+264,92813F-HRTimeline
venBio Partners LLC337,697$4.74M0.91%013F-HRTimeline
GEODE CAPITAL MANAGEMENT, LLCin group GEODE CAPITAL MANAGEMENT, LLC310,636$4.37M<0.01%+143,65613F-HRTimelineGroup
Alphabet Inc.in group Alphabet Inc.293,256$4.12M<0.01%013F-HRTimelineGroup
STATE STREET CORPin group STATE STREET CORP185,322$2.6M<0.01%+112,80013F-HRTimelineGroup
HSG Holding Ltdin group HSG Holding Ltd152,299$2.14M0.18%013F-HRTimelineGroup
RENAISSANCE TECHNOLOGIES LLC130,190$1.83M<0.01%+13,77913F-HRTimeline
NORTHERN TRUST CORPin group NORTHERN TRUST CORP118,500$1.66M<0.01%+88,22013F-HRTimelineGroup
Qube Research & Technologies Ltd110,531$1.55M<0.01%+55,42113F-HRTimeline
CHARLES SCHWAB INVESTMENT MANAGEMENT INCin group Charles Schwab Trust Co107,570$1.51M<0.01%+21,59913F-HRTimelineGroup
MARSHALL WACE, LLPin group MARSHALL WACE, LLP106,300$1.49M<0.01%-42,21613F-HRTimelineGroup
Velan Capital Investment Management LP105,000$1.48M0.9%+3,00013F-HRTimeline
MIC Capital Management UK LLP87,028$1.22M0.31%013F-HRTimeline
GOLDMAN SACHS GROUP INCin group GOLDMAN SACHS GROUP INC86,779$1.22M<0.01%-27,71213F-HRTimelineGroup
DIMENSIONAL FUND ADVISORS LPin group DIMENSIONAL FUND ADVISORS LP68,315$957K<0.01%+20,42713F-HRTimelineGroup
ACADIAN ASSET MANAGEMENT LLCin group ACADIAN ASSET MANAGEMENT LLC59,748$836K<0.01%new13F-HRTimelineGroup
TWO SIGMA INVESTMENTS, LPin group TWO SIGMA INVESTMENTS, LP52,927$744K<0.01%+41,34213F-HRTimelineGroup
JANE STREET GROUP, LLCin group JANE STREET GROUP, LLC46,011$646K<0.01%-17,88213F-HRTimelineGroup
Squarepoint Ops LLCin group Squarepoint Ops LLC42,322$595K<0.01%+23,02813F-HRTimelineGroup
Ikarian Capital, LLC41,081$577K0.09%013F-HRTimeline
MORGAN STANLEYin group MORGAN STANLEY37,050$521K<0.01%-19,10113F-HRTimelineGroup
HRT FINANCIAL LP36,575$513K<0.01%new13F-HRTimeline
PRICE T ROWE ASSOCIATES INC /MD/30,657$431K<0.01%+17,52913F-HRTimeline
CANADA PENSION PLAN INVESTMENT BOARD29,411$413K<0.01%013F-HRTimeline
GSA CAPITAL PARTNERS LLP26,225$368K0.02%new13F-HRTimeline
Point72 Asset Management, L.P.in group Point72 Asset Management, L.P.26,080$366K<0.01%+4,78813F-HRTimelineGroup
UBS Group AGin group UBS Group AG25,982$365K<0.01%-5,83213F-HRTimelineGroup
Bank of New York Mellon Corpin group Bank of New York Mellon Corp24,673$347K<0.01%new13F-HRTimelineGroup
AMERICAN CENTURY COMPANIES INCin group AMERICAN CENTURY COMPANIES INC24,540$345K<0.01%+8,56913F-HRTimelineGroup
Jump Financial, LLCin group Jump Financial, LLC21,956$308K<0.01%+1,83313F-HRTimelineGroup
Clearstead Advisors, LLC19,958$280K<0.01%-19,95813F-HRTimeline
EntryPoint Capital, LLC19,410$273K0.07%new13F-HRTimeline
CITADEL ADVISORS LLCin group CITADEL ADVISORS LLC18,695$263K<0.01%-362,76713F-HRTimelineGroup
BRIDGEWAY CAPITAL MANAGEMENT, LLC18,000$253K<0.01%013F-HRTimeline
SUSQUEHANNA INTERNATIONAL GROUP, LLPgroup of 2 filers holding17,875$251K-313,123Timeline
Allspring Global Investments Holdings, …in group Allspring Global Investments …16,145$227K<0.01%new13F-HRTimelineGroup
RHUMBLINE ADVISERS15,462$217K<0.01%new13F-HRTimeline
Invesco Ltd.in group Invesco Ltd.13,914$195K<0.01%new13F-HRTimelineGroup
Nuveen, LLCin group TIAA12,595$177K<0.01%new13F-HRTimelineGroup
Graham Capital Management, L.P.11,602$163K<0.01%new13F-HRTimeline
Brevan Howard Capital Management LPin group Brevan Howard Capital Managem…11,557$162K<0.01%-1,87813F-HRTimelineGroup
BANK OF AMERICA CORP /DE/in group BANK OF AMERICA CORP /DE/10,871$153K<0.01%-22,45013F-HRTimelineGroup
Walleye Capital LLCin group Walleye Capital LLC10,451$147K<0.01%-11,75613F-HRTimelineGroup
LOS ANGELES CAPITAL MANAGEMENT LLC9,505$134K<0.01%new13F-HRTimeline
DEUTSCHE BANK AG\in group DEUTSCHE BANK AG\9,188$129K<0.01%new13F-HRTimelineGroup
WELLS FARGO & COMPANY/MNin group WELLS FARGO & COMPANY/MN8,005$112K<0.01%+7,88013F-HRTimelineGroup
BNP PARIBAS FINANCIAL MARKETSin group BNP PARIBAS FINANCIAL MARKETS7,845$110K<0.01%+5,74813F-HRTimelineGroup
Mirae Asset Global Investments Co., Ltd.group of 2 filers holding5,377$75.5K+4,269Timeline
CITIGROUP INCin group CITIGROUP INC5,025$70.6K<0.01%-88713F-HRTimelineGroup
BARCLAYS PLCin group BARCLAYS PLC4,715$66.2K<0.01%+3,04413F-HRTimelineGroup
JPMORGAN CHASE & COin group JPMORGAN CHASE & CO4,796$61.1K<0.01%+3,32813F-HRTimelineGroup
NEW YORK STATE COMMON RETIREMENT FUND4,100$57.6K<0.01%new13F-HRTimeline
China Universal Asset Management Co., L…3,714$52.2K<0.01%-5613F-HRTimeline
Police & Firemen's Retirement System of…3,446$48.4K<0.01%new13F-HRTimeline
FMR LLCin group FMR LLC2,151$30.2K<0.01%+32813F-HRTimelineGroup
Tower Research Capital LLC (TRC)in group Tower Research Capital LLC (T…1,364$19.2K<0.01%+6313F-HRTimelineGroup
Legal & General Group Plcin group Legal & General Group Plc917$12.9K<0.01%new13F-HRTimelineGroup
Zurcher Kantonalbank (Zurich Cantonalba…905$12.7K<0.01%+45813F-HRTimeline
Ameritas Investment Partners, Inc.in group Ameritas Investment Partners,…854$12K<0.01%new13F-HRTimelineGroup
JONES FINANCIAL COMPANIES LLLPin group JONES FINANCIAL COMPANIES LLLP1,025$11.9K<0.01%013F-HRTimelineGroup
Russell Investments Group, Ltd.in group Russell Investments Group, Lt…752$10.6K<0.01%new13F-HRTimelineGroup
ROYAL BANK OF CANADAin group ROYAL BANK OF CANADA742$10K<0.01%+49113F-HRTimelineGroup
GF FUND MANAGEMENT CO. LTD.452$6.35K<0.01%-1813F-HRTimeline
Truvestments Capital LLC300$4.21K<0.01%new13F-HRTimeline
SIMPLEX TRADING, LLC226$3.17K<0.01%-46713F-HRTimeline
Sterling Capital Management LLC190$2.67K<0.01%new13F-HRTimeline
Quarry LP179$2.52K<0.01%new13F-HRTimeline
GROUP ONE TRADING LLC88$1.24K<0.01%-1213F-HRTimeline
Caitong International Asset Management …68$955<0.01%new13F-HRTimeline
US BANCORP \DE\in group US BANCORP \DE\58$815<0.01%013F-HRTimelineGroup
Cornerstone Financial Management LLC46$646<0.01%013F-HR/ATimeline
GAMMA Investing LLC35$492<0.01%013F-HRTimeline
NISA INVESTMENT ADVISORS, LLC25$351<0.01%013F-HRTimeline
Optiver Holding B.V.in group Optiver Holding B.V.20$281<0.01%new13F-HRTimelineGroup