Jupiter Topco LLC in group Janus Henderson More: the full row for Jupiter Topco LLC 11,164,803 $77.3M 0.03% 13F-HR Timeline Group BlackRock, Inc. in group BlackRock, Inc. More: the full row for BlackRock, Inc. 7,426,780 $51.4M <0.01% +6,137,230 13F-HR Timeline Group Squadron Capital Management LLC More: the full row for Squadron Capital Management LLC 7,350,000 $50.9M 17.41% -1,124,571 13F-HR Timeline Venrock Adviser, LLC More: the full row for Venrock Adviser, LLC 6,844,305 $47.4M 1.44% +2,000,925 13F-HR Timeline Spruce Street Capital LP More: the full row for Spruce Street Capital LP 6,391,328 $44.2M 8.68% +129,214 13F-HR Timeline VANGUARD GROUP INC group of 4 filers holding More: the full row for VANGUARD GROUP INC 6,136,762 $42.5M +2,581,256 Timeline ADAGE CAPITAL PARTNERS GP, L.L.C. in group ADAGE CAPITAL PARTNERS GP, L.… More: the full row for ADAGE CAPITAL PARTNERS GP, L.L.C. 4,763,158 $33M 0.05% 0 13F-HR Timeline Group Jones Hill Capital LP More: the full row for Jones Hill Capital LP 3,655,075 $25.3M 5.38% +3,312,323 13F-HR Timeline ORBIMED ADVISORS LLC in group ORBIMED ADVISORS LLC More: the full row for ORBIMED ADVISORS LLC 3,631,195 $25.1M 0.48% -1,084,669 13F-HR Timeline Group STATE STREET CORP in group STATE STREET CORP More: the full row for STATE STREET CORP 2,517,550 $17.4M <0.01% +2,160,510 13F-HR Timeline Group GEODE CAPITAL MANAGEMENT, LLC in group GEODE CAPITAL MANAGEMENT, LLC More: the full row for GEODE CAPITAL MANAGEMENT, LLC 2,492,573 $17.3M <0.01% +1,643,890 13F-HR Timeline Group MILLENNIUM MANAGEMENT LLC in group MILLENNIUM MANAGEMENT LLC More: the full row for MILLENNIUM MANAGEMENT LLC 2,361,827 $16.3M 0.01% -1,545,438 13F-HR Timeline Group MARSHALL WACE, LLP in group MARSHALL WACE, LLP More: the full row for MARSHALL WACE, LLP 2,246,839 $15.5M 0.01% -2,234,767 13F-HR Timeline Group Ikarian Capital, LLC More: the full row for Ikarian Capital, LLC 2,148,359 $14.9M 2.43% -540,000 13F-HR Timeline Driehaus Capital Management LLC More: the full row for Driehaus Capital Management LLC 2,132,053 $14.8M 0.09% 0 13F-HR Timeline AMERIPRISE FINANCIAL INC in group AMERIPRISE FINANCIAL INC More: the full row for AMERIPRISE FINANCIAL INC 1,937,972 $13.4M <0.01% +347,026 13F-HR Timeline Group EVENTIDE ASSET MANAGEMENT, LLC More: the full row for EVENTIDE ASSET MANAGEMENT, LLC 1,858,416 $12.9M 0.17% +1,016,310 13F-HR Timeline Balyasny Asset Management L.P. in group Balyasny Asset Management More: the full row for Balyasny Asset Management L.P. 1,520,688 $10.5M 0.02% +1,268,231 13F-HR Timeline Group STEMPOINT CAPITAL LP More: the full row for STEMPOINT CAPITAL LP 1,460,093 $10.1M 1.75% +862,684 13F-HR Timeline Commodore Capital LP in group Commodore Capital LP More: the full row for Commodore Capital LP 1,425,000 $9.86M 0.59% +791,099 13F-HR Timeline Group Polar Capital Holdings Plc in group Polar Capital Holdings Plc More: the full row for Polar Capital Holdings Plc 1,340,428 $9.28M 0.03% -74,193 13F-HR Timeline Group CITADEL ADVISORS LLC in group CITADEL ADVISORS LLC More: the full row for CITADEL ADVISORS LLC 1,061,665 $7.35M <0.01% new 13F-HR Timeline Group Sio Capital Management, LLC More: the full row for Sio Capital Management, LLC 1,003,562 $6.94M 1.19% +38,562 13F-HR Timeline Opaleye Management Inc. More: the full row for Opaleye Management Inc. 935,000 $6.47M 0.59% 0 13F-HR Timeline GREAT POINT PARTNERS LLC More: the full row for GREAT POINT PARTNERS LLC 842,106 $5.83M 1.37% 0 13F-HR Timeline Soleus Capital Management, L.P. More: the full row for Soleus Capital Management, L.P. 842,106 $5.83M 0.2% 0 13F-HR Timeline Boxer Capital Management, LLC More: the full row for Boxer Capital Management, LLC 842,106 $5.83M 0.44% 0 13F-HR Timeline BANK OF AMERICA CORP /DE/ in group BANK OF AMERICA CORP /DE/ More: the full row for BANK OF AMERICA CORP /DE/ 812,059 $5.62M <0.01% +686,118 13F-HR Timeline Group NORTHERN TRUST CORP in group NORTHERN TRUST CORP More: the full row for NORTHERN TRUST CORP 786,257 $5.44M <0.01% +628,523 13F-HR Timeline Group GOLDMAN SACHS GROUP INC in group GOLDMAN SACHS GROUP INC More: the full row for GOLDMAN SACHS GROUP INC 767,624 $5.31M <0.01% +68,585 13F-HR Timeline Group Qube Research & Technologies Ltd More: the full row for Qube Research & Technologies Ltd 691,545 $4.79M 0.01% +38,212 13F-HR Timeline Walleye Capital LLC in group Walleye Capital LLC More: the full row for Walleye Capital LLC 616,238 $4.26M 0.02% new 13F-HR Timeline Group BOOTHBAY FUND MANAGEMENT, LLC More: the full row for BOOTHBAY FUND MANAGEMENT, LLC 564,759 $3.91M 0.07% -164,296 13F-HR Timeline ACADIAN ASSET MANAGEMENT LLC in group ACADIAN ASSET MANAGEMENT LLC More: the full row for ACADIAN ASSET MANAGEMENT LLC 543,394 $3.76M <0.01% -169,146 13F-HR Timeline Group Integral Health Asset Management, LLC More: the full row for Integral Health Asset Management, LLC 500,000 $3.46M 0.14% +50,000 13F-HR Timeline ADAR1 Capital Management, LLC in group ADAR1 Capital Management, LLC More: the full row for ADAR1 Capital Management, LLC 451,918 $3.13M 0.15% 0 13F-HR Timeline Group Knott David M Jr More: the full row for Knott David M Jr 451,000 $3.12M 1.65% +11,700 13F-HR Timeline HighVista Strategies LLC More: the full row for HighVista Strategies LLC 445,799 $3.08M 0.7% new 13F-HR Timeline AdvisorShares Investments LLC More: the full row for AdvisorShares Investments LLC 438,901 $3.04M 0.37% +143,029 13F-HR Timeline Birchview Capital, LP More: the full row for Birchview Capital, LP 408,100 $2.82M 1.32% -1,287 13F-HR Timeline DIADEMA PARTNERS LP More: the full row for DIADEMA PARTNERS LP 361,367 $2.5M 0.88% +160,525 13F-HR Timeline PARSONS CAPITAL MANAGEMENT INC/RI More: the full row for PARSONS CAPITAL MANAGEMENT INC/RI 354,069 $2.45M 0.11% +1,569 13F-HR Timeline Seven Fleet Capital Management LP More: the full row for Seven Fleet Capital Management LP 348,265 $2.41M 0.4% new 13F-HR Timeline Harvest Investment Services, LLC More: the full row for Harvest Investment Services, LLC 340,890 $2.36M 0.36% new 13F-HR Timeline Woodline Partners LP More: the full row for Woodline Partners LP 328,421 $2.27M 0.01% -92,631 13F-HR Timeline DEUTSCHE BANK AG\ in group DEUTSCHE BANK AG\ More: the full row for DEUTSCHE BANK AG\ 318,902 $2.21M <0.01% +94,056 13F-HR Timeline Group SEVEN GRAND MANAGERS, LLC More: the full row for SEVEN GRAND MANAGERS, LLC 315,788 $2.19M 0.09% 0 13F-HR Timeline Bank of New York Mellon Corp in group Bank of New York Mellon Corp More: the full row for Bank of New York Mellon Corp 295,623 $2.05M <0.01% new 13F-HR Timeline Group CHARLES SCHWAB INVESTMENT MANAGEMENT INC in group Charles Schwab Trust Co More: the full row for CHARLES SCHWAB INVESTMENT MANAGEMENT INC 282,717 $1.96M <0.01% +229,636 13F-HR Timeline Group Nuveen, LLC in group TIAA More: the full row for Nuveen, LLC 225,067 $1.56M <0.01% new 13F-HR Timeline Group TWO SIGMA INVESTMENTS, LP in group TWO SIGMA INVESTMENTS, LP More: the full row for TWO SIGMA INVESTMENTS, LP 214,915 $1.49M <0.01% -193,180 13F-HR Timeline Group UBS Group AG in group UBS Group AG More: the full row for UBS Group AG 158,033 $1.09M <0.01% +31,361 13F-HR Timeline Group LOS ANGELES CAPITAL MANAGEMENT LLC More: the full row for LOS ANGELES CAPITAL MANAGEMENT LLC 155,713 $1.08M <0.01% new 13F-HR Timeline GSA CAPITAL PARTNERS LLP More: the full row for GSA CAPITAL PARTNERS LLP 141,443 $979K 0.06% +121,877 13F-HR Timeline RHUMBLINE ADVISERS More: the full row for RHUMBLINE ADVISERS 118,108 $817K <0.01% new 13F-HR Timeline D. E. Shaw & Co., Inc. in group D. E. Shaw & Co., Inc. More: the full row for D. E. Shaw & Co., Inc. 109,474 $758K <0.01% new 13F-HR Timeline Group ALPS ADVISORS INC More: the full row for ALPS ADVISORS INC 106,456 $737K <0.01% new 13F-HR Timeline X-Square Capital, LLC More: the full row for X-Square Capital, LLC 100,000 $692K 0.18% new 13F-HR Timeline MGO ONE SEVEN LLC More: the full row for MGO ONE SEVEN LLC 100,000 $692K 0.01% 0 13F-HR Timeline Eversept Partners, LP More: the full row for Eversept Partners, LP 93,192 $645K 0.04% -184,707 13F-HR Timeline Invesco Ltd. in group Invesco Ltd. More: the full row for Invesco Ltd. 89,671 $621K <0.01% +67,229 13F-HR Timeline Group Informed Momentum Co LLC More: the full row for Informed Momentum Co LLC 88,447 $612K 0.05% -42,488 13F-HR Timeline Verdad Advisers, LP More: the full row for Verdad Advisers, LP 86,994 $602K 0.58% +39,845 13F-HR Timeline Persistent Asset Partners Ltd More: the full row for Persistent Asset Partners Ltd 86,443 $598K 0.19% +35,670 13F-HR Timeline WELLS FARGO & COMPANY/MN in group WELLS FARGO & COMPANY/MN More: the full row for WELLS FARGO & COMPANY/MN 86,263 $597K <0.01% new 13F-HR Timeline Group MORGAN STANLEY in group MORGAN STANLEY More: the full row for MORGAN STANLEY 82,823 $573K <0.01% -115,640 13F-HR Timeline Group PRICE T ROWE ASSOCIATES INC /MD/ More: the full row for PRICE T ROWE ASSOCIATES INC /MD/ 77,668 $538K <0.01% new 13F-HR Timeline CITIGROUP INC in group CITIGROUP INC More: the full row for CITIGROUP INC 71,753 $497K <0.01% +56,339 13F-HR Timeline Group MANGROVE PARTNERS IM, LLC More: the full row for MANGROVE PARTNERS IM, LLC 71,705 $496K 0.03% 0 13F-HR Timeline SEI INVESTMENTS CO in group SEI INVESTMENTS CO More: the full row for SEI INVESTMENTS CO 69,375 $480K <0.01% -97,239 13F-HR Timeline Group AMERICAN CENTURY COMPANIES INC in group AMERICAN CENTURY COMPANIES INC More: the full row for AMERICAN CENTURY COMPANIES INC 67,348 $466K <0.01% new 13F-HR Timeline Group WELLINGTON MANAGEMENT GROUP LLP in group WELLINGTON MANAGEMENT GROUP L… More: the full row for WELLINGTON MANAGEMENT GROUP LLP 63,800 $441K <0.01% new 13F-HR Timeline Group RENAISSANCE TECHNOLOGIES LLC More: the full row for RENAISSANCE TECHNOLOGIES LLC 57,800 $400K <0.01% -109,400 13F-HR Timeline LMR Partners LLP in group LMR Partners LLP More: the full row for LMR Partners LLP 55,600 $385K <0.01% -7,984 13F-HR Timeline Group MetLife Investment Management, LLC in group MetLife Investment Management… More: the full row for MetLife Investment Management, LLC 55,562 $384K <0.01% new 13F-HR Timeline Group BARCLAYS PLC in group BARCLAYS PLC More: the full row for BARCLAYS PLC 51,234 $355K <0.01% -37,719 13F-HR Timeline Group Virtus Investment Advisers, LLC in group Virtus Investment Advisers, L… More: the full row for Virtus Investment Advisers, LLC 49,202 $340K 0.08% new 13F-HR Timeline Group LPL Financial LLC More: the full row for LPL Financial LLC 48,571 $336K <0.01% new 13F-HR Timeline apricus wealth, LLC More: the full row for apricus wealth, LLC 47,462 $328K 0.16% 0 13F-HR Timeline Trexquant Investment LP More: the full row for Trexquant Investment LP 43,746 $303K <0.01% new 13F-HR Timeline MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. in group Mirae Asset Global Investment… More: the full row for MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 43,360 $300K <0.01% new 13F-HR Timeline Group ALLIANCEBERNSTEIN L.P. More: the full row for ALLIANCEBERNSTEIN L.P. 39,600 $276K <0.01% new 13F-HR Timeline JPMORGAN CHASE & CO in group JPMORGAN CHASE & CO More: the full row for JPMORGAN CHASE & CO 39,203 $274K <0.01% new 13F-HR Timeline Group AlTi Global, Inc. in group AlTi Global, Inc. More: the full row for AlTi Global, Inc. 31,975 $221K <0.01% 0 13F-HR Timeline Group Pale Fire Capital SE in group Pale Fire Capital More: the full row for Pale Fire Capital SE 31,650 $219K 0.02% 0 13F-HR Timeline Group SUSQUEHANNA INTERNATIONAL GROUP, LLP in group SUSQUEHANNA INTERNATIONAL GRO… More: the full row for SUSQUEHANNA INTERNATIONAL GROUP, LLP 30,108 $208K <0.01% -981,464 13F-HR Timeline Group Police & Firemen's Retirement System of… More: the full row for Police & Firemen's Retirement System of New Jersey 27,890 $193K <0.01% new 13F-HR Timeline PROFUND ADVISORS LLC More: the full row for PROFUND ADVISORS LLC 27,326 $189K 0.01% new 13F-HR Timeline NEW YORK STATE COMMON RETIREMENT FUND More: the full row for NEW YORK STATE COMMON RETIREMENT FUND 26,000 $180K <0.01% new 13F-HR Timeline MANUFACTURERS LIFE INSURANCE COMPANY, T… in group MANUFACTURERS LIFE INSURANCE … More: the full row for MANUFACTURERS LIFE INSURANCE COMPANY, THE 25,027 $173K <0.01% new 13F-HR Timeline Group Robertson Stephens Wealth Management, L… More: the full row for Robertson Stephens Wealth Management, LLC 25,000 $173K <0.01% 0 13F-HR Timeline State of Wyoming More: the full row for State of Wyoming 20,586 $142K 0.01% +8,005 13F-HR Timeline Rafferty Asset Management, LLC More: the full row for Rafferty Asset Management, LLC 19,903 $138K <0.01% new 13F-HR Timeline INTECH INVESTMENT MANAGEMENT LLC More: the full row for INTECH INVESTMENT MANAGEMENT LLC 19,720 $136K <0.01% new 13F-HR Timeline VOYA INVESTMENT MANAGEMENT LLC in group VOYA INVESTMENT MANAGEMENT LLC More: the full row for VOYA INVESTMENT MANAGEMENT LLC 17,940 $124K <0.01% new 13F-HR Timeline Group PRUDENTIAL FINANCIAL INC in group PRUDENTIAL FINANCIAL INC More: the full row for PRUDENTIAL FINANCIAL INC 16,020 $111K <0.01% new 13F-HR Timeline Group BNP PARIBAS FINANCIAL MARKETS in group BNP PARIBAS FINANCIAL MARKETS More: the full row for BNP PARIBAS FINANCIAL MARKETS 14,429 $99.8K <0.01% +6,109 13F-HR Timeline Group Lido Advisors, LLC in group Lido Advisors, LLC More: the full row for Lido Advisors, LLC 13,905 $96.2K <0.01% 0 13F-HR Timeline Group Keebeck Wealth Management More: the full row for Keebeck Wealth Management 13,000 $90K 0.01% 0 13F-HR Timeline ProShare Advisors LLC More: the full row for ProShare Advisors LLC 12,381 $85.7K <0.01% new 13F-HR Timeline AXQ CAPITAL, LP More: the full row for AXQ CAPITAL, LP 12,093 $83.7K 0.01% new 13F-HR Timeline Scientech Research LLC More: the full row for Scientech Research LLC 11,826 $81.8K 0.07% -2,783 13F-HR Timeline VICTORY CAPITAL MANAGEMENT INC More: the full row for VICTORY CAPITAL MANAGEMENT INC 10,637 $73.6K <0.01% new 13F-HR Timeline World Investment Advisors More: the full row for World Investment Advisors 10,444 $72.7K <0.01% 0 13F-HR Timeline Bedel Financial Consulting, Inc. More: the full row for Bedel Financial Consulting, Inc. 10,000 $69.2K 0.01% 0 13F-HR Timeline Legal & General Group Plc in group Legal & General Group Plc More: the full row for Legal & General Group Plc 9,181 $63.5K <0.01% new 13F-HR Timeline Group Ameritas Investment Partners, Inc. in group Ameritas Investment Partners,… More: the full row for Ameritas Investment Partners, Inc. 8,582 $59.4K <0.01% new 13F-HR Timeline Group Russell Investments Group, Ltd. in group Russell Investments Group, Lt… More: the full row for Russell Investments Group, Ltd. 7,562 $52.3K <0.01% new 13F-HR Timeline Group EverSource Wealth Advisors, LLC in group EverSource Wealth Advisors, L… More: the full row for EverSource Wealth Advisors, LLC 6,816 $47.2K <0.01% new 13F-HR Timeline Group Tower Research Capital LLC (TRC) in group Tower Research Capital LLC (T… More: the full row for Tower Research Capital LLC (TRC) 6,186 $42.8K <0.01% new 13F-HR Timeline Group Caitong International Asset Management … More: the full row for Caitong International Asset Management Co., Ltd 3,250 $22.5K <0.01% +3,214 13F-HR Timeline ROYAL BANK OF CANADA in group ROYAL BANK OF CANADA More: the full row for ROYAL BANK OF CANADA 3,066 $21K <0.01% +2,971 13F-HR Timeline Group ANTIPODES PARTNERS Ltd More: the full row for ANTIPODES PARTNERS Ltd 2,414 $16.7K <0.01% -621 13F-HR Timeline Allworth Financial LP More: the full row for Allworth Financial LP 2,000 $13.8K <0.01% 0 13F-HR Timeline American Capital Advisory, LLC More: the full row for American Capital Advisory, LLC 1,954 $13.5K <0.01% 0 13F-HR Timeline CALIFORNIA STATE TEACHERS RETIREMENT SY… More: the full row for CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 1,302 $9.01K <0.01% new 13F-HR/A Timeline MassMutual Private Wealth & Trust, FSB More: the full row for MassMutual Private Wealth & Trust, FSB 525 $3.63K <0.01% new 13F-HR Timeline Sterling Capital Management LLC More: the full row for Sterling Capital Management LLC 332 $2.3K <0.01% new 13F-HR Timeline FMR LLC in group FMR LLC More: the full row for FMR LLC 160 $1.11K <0.01% new 13F-HR Timeline Group GAMMA Investing LLC More: the full row for GAMMA Investing LLC 41 $284 <0.01% new 13F-HR Timeline SBI Securities Co., Ltd. More: the full row for SBI Securities Co., Ltd. 5 $35 <0.01% -36 13F-HR Timeline OSAIC HOLDINGS, INC. in group OSAIC HOLDINGS, INC. More: the full row for OSAIC HOLDINGS, INC. 5 $34 <0.01% 0 13F-HR Timeline Group Front Row Advisors LLC More: the full row for Front Row Advisors LLC 2 $9 <0.01% new 13F-HR Timeline