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Disclosery

LXRX LEXICON PHARMACEUTICALS INC

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COMMON STOCK (common), issuer CIK 1062822

144 managers (149 13F filers) reported a position in LXRX shares at 2026-06-30, 364,595,242 shares in all. 43 filers opened a position and 30 filers sold out during the quarter.

Managers
144
13F filers
149
New
43
Added
37
Reduced
36
Sold out
30
Shares held by filers
364,595,242

Shares held by filers adds up every 13F filer's report, so a share reported by a parent and by its subsidiary counts twice (H9). Managers counts each filer group once.

13D and 13G filers

No 13D or 13G on this security in the data. Structured 13D/G data starts 2024-12-18.

Insider trades

No Form 4 transaction on this security in the data.

13F holders, Q2 2026

Filers in the available 13F reports with a share position at 2026-06-30, filer groups collapsed to one row (method), largest first. Options and principal amounts are left out. A group row states no % of portfolio, since each member reports its own portfolio: the members' percents are listed under it. A value about 1,000 times or 1/1,000 of the price other filers imply is shown as filed but neither ranks the row nor enters a sum.

HolderSharesValue% of portfolioChangeSource
Artal Group S.A.in group Artal Group S.A.175,156,062$420M45.15%+20,421,73513F-HRTimelineGroup
FMR LLCin group FMR LLC51,782,045$124M0.01%+6,725,70713F-HRTimelineGroup
Siren, L.L.C.in group Siren, L.L.C.44,303,518$106M2.16%013F-HRTimelineGroup
Sessa Capital IM, L.P.18,960,836$45.5M0.79%+1,047,87513F-HRTimeline
BlackRock, Inc.in group BlackRock, Inc.17,348,741$41.6M<0.01%+14,026,52213F-HRTimelineGroup
VANGUARD GROUP INCgroup of 5 filers holding14,025,808$33.7M+2,479,151Timeline
Point72 Asset Management, L.P.in group Point72 Asset Management, L.P.8,251,325$19.8M0.03%+436,71913F-HRTimelineGroup
GEODE CAPITAL MANAGEMENT, LLCin group GEODE CAPITAL MANAGEMENT, LLC6,244,372$15M<0.01%+3,075,26113F-HRTimelineGroup
STATE STREET CORPin group STATE STREET CORP4,917,769$11.8M<0.01%+3,953,73113F-HRTimelineGroup
NORTHERN TRUST CORPin group NORTHERN TRUST CORP1,968,619$4.72M<0.01%+1,473,95313F-HRTimelineGroup
CHARLES SCHWAB INVESTMENT MANAGEMENT INCin group Charles Schwab Trust Co1,956,775$4.7M<0.01%+645,47713F-HRTimelineGroup
CITADEL ADVISORS LLCin group CITADEL ADVISORS LLC1,601,182$3.84M<0.01%+506,28113F-HRTimelineGroup
Ishara Investments LP1,271,000$3.05M2.24%+369,00013F-HRTimeline
MILLENNIUM MANAGEMENT LLCin group MILLENNIUM MANAGEMENT LLC1,134,229$2.72M<0.01%-3,810,50213F-HRTimelineGroup
RENAISSANCE TECHNOLOGIES LLC1,127,000$2.7M<0.01%-473,50013F-HRTimeline
MACKENZIE FINANCIAL CORP963,354$2.31M<0.01%+190,67713F-HRTimeline
ADAR1 Capital Management, LLCin group ADAR1 Capital Management, LLC750,000$1.8M0.08%013F-HRTimelineGroup
SUSQUEHANNA INTERNATIONAL GROUP, LLPin group SUSQUEHANNA INTERNATIONAL GRO…696,776$1.67M<0.01%-1,424,38813F-HRTimelineGroup
ACADIAN ASSET MANAGEMENT LLCin group ACADIAN ASSET MANAGEMENT LLC696,617$1.67M<0.01%+251,32913F-HRTimelineGroup
UBS Group AGin group UBS Group AG684,713$1.64M<0.01%-1,798,46913F-HRTimelineGroup
TWO SIGMA INVESTMENTS, LPin group TWO SIGMA INVESTMENTS, LP643,444$1.54M<0.01%-556,18813F-HRTimelineGroup
TIAAgroup of 2 filers holding606,664$1.46M+586,664Timeline
Bank of New York Mellon Corpin group Bank of New York Mellon Corp568,706$1.36M<0.01%+541,24713F-HRTimelineGroup
Invesco Ltd.in group Invesco Ltd.508,071$1.22M<0.01%-4,35513F-HRTimelineGroup
GOLDMAN SACHS GROUP INCin group GOLDMAN SACHS GROUP INC485,546$1.17M<0.01%-584,97113F-HRTimelineGroup
Compagnie Lombard Odier SCmA480,000$1.15M0.01%-30,00013F-HRTimeline
BANK OF AMERICA CORP /DE/in group BANK OF AMERICA CORP /DE/421,299$1.01M<0.01%-104,80413F-HRTimelineGroup
GSA CAPITAL PARTNERS LLP397,219$953K0.06%-532,87013F-HRTimeline
BARCLAYS PLCin group BARCLAYS PLC387,483$930K<0.01%+281,99613F-HRTimelineGroup
XTX Topco Ltdin group XTX Topco Ltd357,877$859K0.01%+43,26313F-HRTimelineGroup
Janney Montgomery Scott LLC295,548$709K<0.01%new13F-HRTimeline
CANADA PENSION PLAN INVESTMENT BOARD257,900$619K<0.01%new13F-HRTimeline
RHUMBLINE ADVISERS256,885$617K<0.01%+256,88513F-HRTimeline
DEUTSCHE BANK AG\in group DEUTSCHE BANK AG\247,528$594K<0.01%new13F-HRTimelineGroup
WELLS FARGO & COMPANY/MNin group WELLS FARGO & COMPANY/MN230,470$553K<0.01%+222,71013F-HRTimelineGroup
PRICE T ROWE ASSOCIATES INC /MD/204,391$491K<0.01%new13F-HRTimeline
WELLINGTON MANAGEMENT GROUP LLPin group WELLINGTON MANAGEMENT GROUP L…179,700$431K<0.01%new13F-HRTimelineGroup
CITIGROUP INCin group CITIGROUP INC175,205$420K<0.01%+8,80713F-HRTimelineGroup
GROUP ONE TRADING LLC175,013$420K0.01%-9,99313F-HRTimeline
Virtus Investment Advisers, LLCin group Virtus Investment Advisers, L…170,415$409K0.1%new13F-HRTimelineGroup
Headlands Technologies LLC167,198$401K0.04%-24,12413F-HRTimeline
Ikarian Capital, LLC164,674$395K0.06%013F-HRTimeline
Quarry LP156,186$375K0.06%+46,18613F-HRTimeline
MetLife Investment Management, LLCin group MetLife Investment Management…146,410$351K<0.01%new13F-HRTimelineGroup
MORGAN STANLEYin group MORGAN STANLEY132,902$319K<0.01%-86,96013F-HRTimelineGroup
PANAGORA ASSET MANAGEMENT INC132,042$317K<0.01%new13F-HRTimeline
JPMORGAN CHASE & COin group JPMORGAN CHASE & CO109,839$290K<0.01%new13F-HRTimelineGroup
State of Wyoming119,090$286K0.03%+108,31113F-HRTimeline
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.in group Mirae Asset Global Investment…114,114$274K<0.01%new13F-HRTimelineGroup
Cornerstone Investment Partners, LLC113,739$273K0.01%new13F-HRTimeline
Cerity Partners LLCin group Cerity Partners LLC98,400$236K<0.01%-12,05813F-HRTimelineGroup
ALGERT GLOBAL LLC92,150$221K<0.01%new13F-HRTimeline
BANK OF NOVA SCOTIAin group BANK OF NOVA SCOTIA86,607$208K<0.01%+12,90013F-HRTimelineGroup
LPL Financial LLC84,916$204K<0.01%+15,13313F-HRTimeline
AQR CAPITAL MANAGEMENT LLCin group AQR CAPITAL MANAGEMENT LLC75,230$181K<0.01%-21,00413F-HRTimelineGroup
Police & Firemen's Retirement System of…73,402$176K<0.01%new13F-HRTimeline
UNIVERSITY OF TEXAS/TEXAS AM INVESTMENT…71,427$171K0.02%+35,71313F-HRTimeline
PRUDENTIAL FINANCIAL INCin group PRUDENTIAL FINANCIAL INC71,345$171K<0.01%+37,54513F-HRTimelineGroup
MANUFACTURERS LIFE INSURANCE COMPANY, T…in group MANUFACTURERS LIFE INSURANCE …69,747$167K<0.01%new13F-HRTimelineGroup
NEW YORK STATE COMMON RETIREMENT FUND68,400$164K<0.01%new13F-HRTimeline
TWO SIGMA SECURITIES, LLC66,375$159K0.01%new13F-HRTimeline
SEI INVESTMENTS COin group SEI INVESTMENTS CO63,937$153K<0.01%new13F-HRTimelineGroup
Straight Path Wealth Management62,666$150K0.04%013F-HRTimeline
R Squared Ltd54,985$132K0.07%-12,54113F-HRTimeline
Fortis Group Advisors, LLC50,000$120K0.02%013F-HRTimeline
Schonfeld Strategic Advisors LLC49,435$119K<0.01%-25,67513F-HRTimeline
SCOTIA CAPITAL INC.48,871$117K<0.01%-110,96013F-HRTimeline
PROFUND ADVISORS LLC48,586$117K<0.01%new13F-HRTimeline
VOYA INVESTMENT MANAGEMENT LLCin group VOYA INVESTMENT MANAGEMENT LLC47,771$115K<0.01%new13F-HRTimelineGroup
AXQ CAPITAL, LP45,727$110K0.01%+25,57713F-HRTimeline
BOOTHBAY FUND MANAGEMENT, LLC44,315$106K<0.01%013F-HRTimeline
ALLIANCEBERNSTEIN L.P.67,800$106K<0.01%new13F-HRTimeline
WINTON GROUP Ltdin group WINTON GROUP Ltd43,200$104K<0.01%+17,70013F-HRTimelineGroup
INTECH INVESTMENT MANAGEMENT LLC42,491$102K<0.01%new13F-HRTimeline
LMR Partners LLPin group LMR Partners LLP41,091$98.6K<0.01%+17,78613F-HRTimelineGroup
BANK OF MONTREAL /CAN/in group BANK OF MONTREAL /CAN/40,000$96K<0.01%-30,00013F-HRTimelineGroup
BNP PARIBAS FINANCIAL MARKETSin group BNP PARIBAS FINANCIAL MARKETS37,780$90.7K<0.01%+20,23013F-HRTimelineGroup
Rafferty Asset Management, LLC34,090$81.8K<0.01%new13F-HRTimeline
ProShare Advisors LLC32,588$78.2K<0.01%new13F-HRTimeline
Leonteq Securities AG30,000$72K<0.01%013F-HRTimeline
Pathstone Holdings, LLCin group Pathstone Holdings, LLC29,969$71.9K<0.01%+19513F-HRTimelineGroup
PINNACLE ASSOCIATES LTD29,015$69.6K<0.01%013F-HRTimeline
VICTORY CAPITAL MANAGEMENT INC24,223$58.1K<0.01%+1,54413F-HRTimeline
Legal & General Group Plcin group Legal & General Group Plc24,185$58K<0.01%new13F-HRTimelineGroup
XPONANCE LLC23,763$57K<0.01%new13F-HRTimeline
Graham Capital Management, L.P.23,541$56.5K<0.01%-10,48613F-HRTimeline
Ameritas Investment Partners, Inc.in group Ameritas Investment Partners,…22,986$55.2K<0.01%new13F-HRTimelineGroup
D. E. Shaw & Co., Inc.in group D. E. Shaw & Co., Inc.22,200$53.3K<0.01%new13F-HRTimelineGroup
Quadrature Capital Ltdin group Quadrature Capital Ltd21,998$52.8K<0.01%-88,38113F-HRTimelineGroup
WEDBUSH SECURITIES INC20,000$48K<0.01%-20,85013F-HRTimeline
DIKER MANAGEMENT LLCin group DIKER MANAGEMENT LLC20,000$48K0.04%013F-HRTimelineGroup
Invera Wealth Advisors, LLC20,000$48K0.03%013F-HRTimeline
Russell Investments Group, Ltd.in group Russell Investments Group, Lt…19,902$47.8K<0.01%new13F-HRTimelineGroup
Tower Research Capital LLC (TRC)in group Tower Research Capital LLC (T…19,486$46.8K<0.01%new13F-HRTimelineGroup
SBI Securities Co., Ltd.19,205$46.1K<0.01%+15,12413F-HRTimeline
PRINCIPAL FINANCIAL GROUP INCin group PRINCIPAL FINANCIAL GROUP INC19,034$45.7K<0.01%new13F-HRTimelineGroup
CREDIT AGRICOLE S Ain group CREDIT AGRICOLE S A18,975$45.5K<0.01%013F-HRTimelineGroup
CAPTRUST FINANCIAL ADVISORS15,321$36.8K<0.01%-12913F-HRTimeline
Callan Family Office, LLCin group Callan Family Office, LLC14,090$33.8K<0.01%013F-HRTimelineGroup
TRUIST FINANCIAL CORPin group TRUIST FINANCIAL CORP14,000$33.6K<0.01%013F-HRTimelineGroup
CIBC Bancorp USA Inc.in group CIBC Bancorp USA Inc.13,740$33K<0.01%-1,786,26013F-HRTimelineGroup
Gotham Asset Management, LLC13,627$32.7K<0.01%new13F-HRTimeline
CIBC Asset Management Inc13,102$31.4K<0.01%-26,41813F-HRTimeline
ROYAL BANK OF CANADAin group ROYAL BANK OF CANADA12,650$30K<0.01%+11,09913F-HRTimelineGroup
HBK Sorce Advisory LLC11,786$28.9K<0.01%013F-HRTimeline
Squarepoint Ops LLCin group Squarepoint Ops LLC11,741$28.2K<0.01%new13F-HRTimelineGroup
Apollon Wealth Management, LLCin group Apollon Wealth Management, LLC11,378$27.3K<0.01%new13F-HRTimelineGroup
Mariner, LLCin group Mariner, LLC11,239$27K<0.01%+16713F-HRTimelineGroup
WEALTH ENHANCEMENT ADVISORY SERVICES, L…12,139$26.9K<0.01%-24913F-HRTimeline
Perennial Investment Advisors, LLC10,990$26.4K<0.01%013F-HRTimeline
Cetera Investment Advisers10,524$25.3K<0.01%-2,10913F-HRTimeline
NBT BANK, N.A.in group NBT BANK, N.A.10,000$24K<0.01%013F-HRTimelineGroup
Berger Financial Group, Inc10,000$24K<0.01%013F-HRTimeline
SIMPLEX TRADING, LLC8,540$20.5K<0.01%new13F-HRTimeline
CALIFORNIA STATE TEACHERS RETIREMENT SY…3,427$8.22K<0.01%new13F-HR/ATimeline
NISA INVESTMENT ADVISORS, LLC2,592$6.22K<0.01%013F-HRTimeline
Integrated Wealth Concepts LLC2,077$4.99K<0.01%new13F-HRTimeline
PNC Financial Services Group, Inc.in group PNC Financial Services Group,…1,461$3.51K<0.01%013F-HRTimelineGroup
Physician Wealth Advisors, Inc.1,412$3.39K<0.01%013F-HRTimeline
Rialto Wealth Management, LLC1,313$3.15K<0.01%013F-HRTimeline
Global Retirement Partners, LLC1,000$2.4K<0.01%13F-HRTimeline
Cassaday & Co Wealth Management LLC1,000$2.4K<0.01%013F-HRTimeline
MassMutual Private Wealth & Trust, FSB957$2.3K<0.01%new13F-HRTimeline
Sterling Capital Management LLC874$2.1K<0.01%new13F-HRTimeline
Avion Wealth1,115$2K<0.01%-21813F-HRTimeline
Aster Capital Management (DIFC) Ltd743$1.78K<0.01%new13F-HR/ATimeline
Fortitude Family Office, LLC706$1.69K<0.01%013F-HRTimeline
Basecamp Wealth Advisors LLC691$1.66K<0.01%013F-HRTimeline
NORTHWESTERN MUTUAL WEALTH MANAGEMENT COin group NORTHWESTERN MUTUAL INVESTMEN…500$1.2K<0.01%-313F-HRTimelineGroup
Steward Partners Investment Advisory, L…400$960<0.01%-10013F-HRTimeline
JONES FINANCIAL COMPANIES LLLPin group JONES FINANCIAL COMPANIES LLLP356$908<0.01%013F-HRTimelineGroup
Rockefeller Capital Management L.P.in group Rockefeller Capital Managemen…300$720<0.01%-3513F-HRTimelineGroup
Allworth Financial LP263$632<0.01%new13F-HRTimeline
Parallel Advisors, LLC247$593<0.01%013F-HRTimeline
OSAIC HOLDINGS, INC.in group OSAIC HOLDINGS, INC.163$390<0.01%-50013F-HRTimelineGroup
Caitong International Asset Management …157$377<0.01%-19613F-HRTimeline
SYNTAX RESEARCH, INC.142$341<0.01%013F-HRTimeline
Clearstead Advisors, LLC100$240<0.01%new13F-HRTimeline
Larson Financial Group LLC100$240<0.01%013F-HRTimeline
Arax Advisory Partners41$98<0.01%013F-HRTimeline
HM PAYSON & CO37$89<0.01%013F-HRTimeline
Blume Capital Management, Inc.5$12<0.01%new13F-HRTimeline
Farther Finance Advisors, LLC2$5<0.01%-25313F-HRTimeline
Covestor Ltd81$00%013F-HRTimelineValue filed as zero, left out of ratios.