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Disclosery

QURE UNIQURE NV

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SHS (common), issuer CIK 1590560

219 managers (226 13F filers) reported a position in QURE shares at 2025-12-31, 61,956,259 shares in all. 62 filers opened a position and 63 filers sold out during the quarter.

Managers
219
13F filers
226
New
62
Added
73
Reduced
61
Sold out
63
Shares held by filers
61,956,259

Shares held by filers adds up every 13F filer's report, so a share reported by a parent and by its subsidiary counts twice (H9). Managers counts each filer group once.

13D and 13G filers

No 13D or 13G on this security in the data. Structured 13D/G data starts 2024-12-18.

Insider trades

No Form 4 transaction on this security in the data.

13F holders, Q4 2025

Filers in the available 13F reports with a share position at 2025-12-31, filer groups collapsed to one row (method), largest first. Options and principal amounts are left out. A group row states no % of portfolio, since each member reports its own portfolio: the members' percents are listed under it. A value about 1,000 times or 1/1,000 of the price other filers imply is shown as filed but neither ranks the row nor enters a sum.

HolderSharesValue% of portfolioChangeSource
FMR LLCin group FMR LLC6,240,936$149M0.01%+181,36213F-HRTimelineGroup
Avoro Capital Advisors LLC6,150,000$147M1.45%+1,705,55613F-HR/ATimeline
RTW INVESTMENTS, LP3,711,462$88.8M0.89%-713,50613F-HRTimeline
Aberdeen Group plcin group Aberdeen Group plc3,678,640$88M0.14%+738,89713F-HRTimelineGroup
STATE STREET CORPin group STATE STREET CORP3,231,043$77.3M<0.01%+1,787,03313F-HRTimelineGroup
JPMORGAN CHASE & COin group JPMORGAN CHASE & CO2,934,626$70.2M<0.01%+1,785,27513F-HRTimelineGroup
TWO SIGMA INVESTMENTS, LPgroup of 2 filers holding2,561,684$61.3M+1,254,646Timeline
BlackRock, Inc.in group BlackRock, Inc.1,974,988$47.3M<0.01%+528,88913F-HRTimelineGroup
MPM BIOIMPACT LLC1,381,628$33.1M3.78%new13F-HRTimeline
JENNISON ASSOCIATES LLC1,371,190$32.8M0.02%+371,70613F-HRTimeline
SUSQUEHANNA INTERNATIONAL GROUP, LLPgroup of 2 filers holding1,247,058$29.8M+991,970Timeline
MONTANOVA CAPITAL, LLC1,216,734$29.1M0.73%new13F-HRTimeline
GOLDMAN SACHS GROUP INCin group GOLDMAN SACHS GROUP INC1,167,608$27.9M<0.01%+505,40013F-HR/ATimelineGroup
VANGUARD GROUP INCgroup of 2 filers holding1,063,735$25.5M-73,812Timeline
Artia Global Partners LP1,023,539$24.5M3.94%+364,70013F-HRTimeline
Integral Health Asset Management, LLC900,000$21.5M1.09%+300,00013F-HRTimeline
MILLENNIUM MANAGEMENT LLCin group MILLENNIUM MANAGEMENT LLC803,605$19.2M0.01%+612,00513F-HRTimelineGroup
GEODE CAPITAL MANAGEMENT, LLCin group GEODE CAPITAL MANAGEMENT, LLC776,071$18.6M<0.01%+54,41913F-HRTimelineGroup
Fiera Capital Corpin group Fiera Capital Corp768,510$18.4M0.06%new13F-HRTimelineGroup
FRANKLIN RESOURCES INCin group Franklin Resources746,602$17.9M<0.01%-1,241,97913F-HRTimelineGroup
ORBIMED ADVISORS LLCin group ORBIMED ADVISORS LLC737,400$17.6M0.36%+278,90013F-HRTimelineGroup
MORGAN STANLEYin group MORGAN STANLEY716,927$17.2M<0.01%+395,42613F-HR/ATimelineGroup
Nantahala Capital Management, LLCin group Nantahala Capital Management,…699,298$16.7M1%-308,19413F-HRTimelineGroup
Logos Global Management LP675,000$16.2M1.08%+375,00013F-HRTimeline
Tyro Capital Management LLC663,929$15.9M4.94%new13F-HR/ATimeline
MAVERICK CAPITAL LTD661,820$15.8M0.17%new13F-HRTimeline
Assenagon Asset Management S.A.606,923$14.5M0.02%new13F-HRTimeline
UBS Group AGgroup of 2 filers holding571,703$13.7M+366,714Timeline
Nationale-Nederlanden Powszechne Towarz…521,677$12.5M1.11%013F-HRTimeline
EVENTIDE ASSET MANAGEMENT, LLC498,212$11.9M0.19%new13F-HRTimeline
CITADEL ADVISORS LLCin group CITADEL ADVISORS LLC469,300$11.2M0.01%+39,59013F-HRTimelineGroup
Whitefort Capital Management, LP459,000$11M3.32%new13F-HRTimeline
Privium Fund Management B.V.416,270$9.96M1.83%+30,27013F-HRTimeline
683 Capital Management, LLCin group 683 Capital Management, LLC384,950$9.21M0.77%-685,05013F-HRTimelineGroup
CHARLES SCHWAB INVESTMENT MANAGEMENT INCin group Charles Schwab Trust Co362,878$8.68M<0.01%+5,19313F-HRTimelineGroup
READYSTATE ASSET MANAGEMENT LP361,560$8.65M0.38%new13F-HRTimeline
FRED ALGER MANAGEMENT, LLCin group FRED ALGER MANAGEMENT, LLC344,878$8.25M0.03%-945,51313F-HRTimelineGroup
BANK OF AMERICA CORP /DE/in group BANK OF AMERICA CORP /DE/329,525$7.89M<0.01%+34,39413F-HRTimelineGroup
First Turn Management, LLC321,655$7.7M0.88%new13F-HRTimeline
HRT FINANCIAL LP310,050$7.42M0.02%new13F-HRTimeline
Jump Financial, LLCin group Jump Financial, LLC306,131$7.33M0.09%+302,30513F-HRTimelineGroup
Boxer Capital Management, LLCin group Boxer Capital Management, LLC290,000$6.94M1.52%-510,00013F-HRTimelineGroup
Catalio Capital Management, LPin group Catalio Capital Management, LP288,345$6.9M1.22%+5,40513F-HR/ATimelineGroup
NOMURA ASSET MANAGEMENT CO LTDgroup of 2 filers holding273,795$6.55MnewTimeline
Parkman Healthcare Partners LLC257,382$6.16M0.59%-87,97413F-HRTimeline
ADAR1 Capital Management, LLCin group ADAR1 Capital Management, LLC235,155$5.63M0.42%+101,83913F-HR/ATimelineGroup
Freshford Capital Management, LLCin group Freshford Capital Management,…229,613$5.49M2.2%new13F-HRTimelineGroup
BNP PARIBAS FINANCIAL MARKETSin group BNP PARIBAS FINANCIAL MARKETS221,343$5.3M<0.01%-164,26613F-HRTimelineGroup
Voss Capital, LP210,000$5.03M0.27%+85,00013F-HRTimeline
BARCLAYS PLCin group BARCLAYS PLC209,790$5.02M<0.01%+94,22813F-HRTimelineGroup
PRICE T ROWE ASSOCIATES INC /MD/208,646$4.99M<0.01%-704,53413F-HRTimeline
Eagle Health Investments LP205,247$4.91M1.08%new13F-HRTimeline
CITIGROUP INCin group CITIGROUP INC184,765$4.42M<0.01%+173,19013F-HRTimelineGroup
Caption Management, LLC177,277$4.24M0.19%-281,02313F-HRTimeline
Sofinnova Investments, Inc.176,513$4.22M0.18%+39,65113F-HRTimeline
Squarepoint Ops LLCin group Squarepoint Ops LLC176,000$4.21M0.01%-5,90213F-HRTimelineGroup
NORTHERN TRUST CORPin group NORTHERN TRUST CORP168,820$4.04M<0.01%+16,38313F-HRTimelineGroup
Rafferty Asset Management, LLC164,937$3.95M0.01%+82,08113F-HRTimeline
Alyeska Investment Group, L.P.in group Alyeska Investment Group, L.P.151,058$3.61M0.01%+111,05813F-HRTimelineGroup
NEW YORK STATE COMMON RETIREMENT FUND147,549$3.53M<0.01%new13F-HRTimeline
FLAX POND CAPITAL, LLC146,498$3.51M2.61%13F-HRTimeline
Balyasny Asset Management L.P.in group Balyasny Asset Management135,644$3.25M0.01%-197,59113F-HRTimelineGroup
D. E. Shaw & Co., Inc.in group D. E. Shaw & Co., Inc.131,956$3.16M<0.01%+99,41913F-HRTimelineGroup
SILVERARC CAPITAL MANAGEMENT, LLCin group SILVERARC CAPITAL MANAGEMENT,…126,047$3.02M0.44%-328,95313F-HRTimelineGroup
Hudson Bay Capital Management LPin group Hudson Bay Capital Management…125,500$3M0.02%+121,18213F-HRTimelineGroup
Schonfeld Strategic Advisors LLC122,529$2.93M0.01%-65,66813F-HRTimeline
NAN FUNG TRINITY (HK) LTD115,494$2.76M0.22%new13F-HRTimeline
SIMPLEX TRADING, LLC110,675$2.65M0.07%+42,68013F-HRTimeline
ENVESTNET ASSET MANAGEMENT INCin group ENVESTNET ASSET MANAGEMENT INC99,593$2.38M<0.01%+88,04413F-HRTimelineGroup
Ikarian Capital, LLCin group Ikarian Capital, LLC91,060$2.18M0.28%+32,45013F-HRTimelineGroup
Jefferies Financial Group Inc.in group Jefferies Financial Group Inc.90,542$2.17M0.02%013F-HRTimelineGroup
Deeter Investments LLP89,085$2.13M0.46%13F-HRTimeline
Walleye Capital LLCgroup of 2 filers holding86,653$2.07M-63,577Timeline
Marex Group Ltdin group Marex Group Ltd85,993$2.06M0.02%-86613F-HRTimelineGroup
ROYAL BANK OF CANADAin group ROYAL BANK OF CANADA85,640$2.05M<0.01%-125,77313F-HRTimelineGroup
Clearline Capital LP83,681$2M0.15%new13F-HRTimeline
CAPITAL FUND MANAGEMENT S.A.82,978$1.99M0.02%new13F-HRTimeline
Rhenman & Partners Asset Management AB79,375$1.9M0.18%new13F-HRTimeline
Swiss National Bank79,000$1.89M<0.01%+2,70013F-HRTimeline
Atom Investors LP78,209$1.87M0.15%+30,91813F-HRTimeline
MOORE CAPITAL MANAGEMENT, LP75,000$1.79M0.04%new13F-HRTimeline
TUDOR INVESTMENT CORP ET AL74,036$1.77M0.01%+45,31913F-HRTimeline
ExodusPoint Capital Management, LP73,775$1.77M0.02%new13F-HRTimeline
ALGERT GLOBAL LLC72,150$1.73M0.03%+49,34013F-HR/ATimeline
AMERIPRISE FINANCIAL INCin group AMERIPRISE FINANCIAL INC70,796$1.69M<0.01%-88,14713F-HRTimelineGroup
WELLS FARGO & COMPANY/MNin group WELLS FARGO & COMPANY/MN70,236$1.68M<0.01%+59,39313F-HRTimelineGroup
Hennion & Walsh Asset Management, Inc.67,739$1.62M0.06%+16,12613F-HRTimeline
SG Americas Securities, LLC64,326$1.54M<0.01%+53,74713F-HRTimeline
Eversept Partners, LP62,820$1.5M0.08%-814,55313F-HRTimeline
PROFUND ADVISORS LLC59,463$1.42M0.04%+42,37913F-HRTimeline
SCHRODER INVESTMENT MANAGEMENT GROUP55,015$1.31M<0.01%new13F-HRTimeline
Senvest Management, LLC50,000$1.2M0.04%new13F-HRTimeline
Affinity Asset Advisors, LLC50,000$1.2M0.09%-250,00013F-HRTimeline
WINTON GROUP Ltdin group WINTON GROUP Ltd48,185$1.15M0.04%+7,20913F-HRTimelineGroup
Mirae Asset Global Investments Co., Ltd.group of 2 filers holding47,277$1.13M+7,867Timeline
STIFEL FINANCIAL CORPin group STIFEL FINANCIAL CORP45,987$1.1M<0.01%-12,28913F-HRTimelineGroup
Y-Intercept (Hong Kong) Ltd45,778$1.1M0.02%+23,07413F-HRTimeline
DIADEMA PARTNERS LP45,000$1.08M0.64%new13F-HRTimeline
STEMPOINT CAPITAL LP43,485$1.04M0.18%-478,67013F-HRTimeline
Engineers Gate Manager LP43,356$1.04M0.01%new13F-HRTimeline
Bank of New York Mellon Corpin group Bank of New York Mellon Corp43,309$1.04M<0.01%+21,09813F-HRTimelineGroup
Tejara Capital Ltd42,000$1.01M0.42%new13F-HRTimeline
Shay Capital LLC41,073$983K0.16%+6,07613F-HRTimeline
Massar Capital Management, LP40,529$970K0.19%+20,52913F-HRTimeline
Headlands Technologies LLC39,616$948K0.08%-17,79213F-HRTimeline
PFM Health Sciences, LP39,499$945K0.1%-6,85413F-HRTimeline
CI INVESTMENTS INC.in group CI INVESTMENTS INC.37,841$906K<0.01%-9,59513F-HRTimelineGroup
CALIFORNIA STATE TEACHERS RETIREMENT SY…35,947$860K<0.01%+4,63613F-HRTimeline
MML INVESTORS SERVICES, LLC33,937$812K<0.01%new13F-HRTimeline
Diamond Hill Capital Management, LLC (I…33,333$798K<0.01%013F-HRTimeline
Legal & General Group Plcin group Legal & General Group Plc31,964$765K<0.01%-3,65713F-HRTimelineGroup
BIT Capital GmbH31,614$757K0.03%new13F-HRTimeline
Birchview Capital, LP30,789$737K0.43%-47,93913F-HRTimeline
SECTORAL ASSET MANAGEMENT INC30,585$732K0.59%-15513F-HRTimeline
BOOTHBAY FUND MANAGEMENT, LLC30,448$729K0.02%-8,95513F-HRTimeline
Havemeyer Place LP29,655$710K0.14%13F-HRTimeline
Pekin Hardy Strauss, Inc.29,300$701K0.06%new13F-HRTimeline
VOYA INVESTMENT MANAGEMENT LLCin group VOYA INVESTMENT MANAGEMENT LLC28,850$690K<0.01%-73,27413F-HRTimelineGroup
SummitTX Capital, L.P.27,708$663K0.02%+22,01013F-HRTimeline
DNB Asset Management ASin group DNB Asset Management AS27,342$654K<0.01%+15,54013F-HRTimelineGroup
MONIMUS CAPITAL MANAGEMENT, LP25,878$619K0.41%new13F-HRTimeline
Monaco Asset Management SAM25,000$598K0.18%-14,91313F-HRTimeline
Point72 Asset Management, L.P.in group Point72 Asset Management, L.P.24,439$585K<0.01%-229,64313F-HRTimelineGroup
TD Asset Management Inc23,734$568K<0.01%-71,41013F-HRTimeline
Russell Investments Group, Ltd.in group Russell Investments Group, Lt…23,707$567K<0.01%-126,14413F-HRTimelineGroup
LPL Financial LLC21,969$526K<0.01%-24,14513F-HRTimeline
MARSHALL WACE, LLPin group MARSHALL WACE, LLP21,159$506K<0.01%-87,05113F-HRTimelineGroup
J. Goldman & Co LP20,250$485K0.02%new13F-HRTimeline
Voleon Capital Management LP20,243$484K0.01%new13F-HRTimeline
Burkehill Global Management, LP20,000$479K0.03%013F-HRTimeline
STATE OF WISCONSIN INVESTMENT BOARD19,390$464K<0.01%+15,82213F-HRTimeline
Zurcher Kantonalbank (Zurich Cantonalba…19,007$455K<0.01%-89013F-HRTimeline
ASSETMARK, INCin group ASSETMARK, INC18,613$445K<0.01%new13F-HRTimelineGroup
Clear Harbor Asset Management, LLC16,900$404K0.03%+9,90013F-HRTimeline
JANUS HENDERSON GROUP PLCin group Janus Henderson16,900$404K<0.01%-3,00013F-HRTimelineGroup
MANUFACTURERS LIFE INSURANCE COMPANY, T…in group MANUFACTURERS LIFE INSURANCE …16,462$391K<0.01%-32,30013F-HRTimelineGroup
Qsemble Capital Management, LP15,931$381K0.03%new13F-HRTimeline
PRELUDE CAPITAL MANAGEMENT, LLC15,739$377K0.03%+3,57913F-HRTimeline
Handelsbanken Fonder AB14,900$357K<0.01%new13F-HRTimeline
Lion Point Capital, LP14,700$352K1.82%new13F-HRTimeline
FARALLON CAPITAL MANAGEMENT, L.L.C.14,000$335K<0.01%-551,00013F-HRTimelineThe filing omitted confidential holdings, a later amendment may add them.
SEI INVESTMENTS COin group SEI INVESTMENTS CO13,938$333K<0.01%-53,33513F-HRTimelineGroup
Virtus Investment Advisers, LLCin group Virtus Investment Advisers, L…13,636$326K0.09%+6,52013F-HRTimelineGroup
Lido Advisors, LLCin group Lido Advisors, LLC5,544$324K<0.01%013F-HRTimelineGroup
FORA Capital, LLC13,313$319K0.04%new13F-HRTimeline
Freestone Grove Partners LP12,984$311K<0.01%new13F-HRTimeline
Lighthouse Investment Partners, LLCin group Lighthouse Investment Partner…12,500$299K0.01%new13F-HRTimelineGroup
Vontobel Holding Ltd.in group Vontobel Holding Ltd.11,933$286K<0.01%new13F-HRTimelineGroup
Diametric Capital, LP11,822$283K0.08%+6,43913F-HRTimeline
ARIZONA STATE RETIREMENT SYSTEM11,141$267K<0.01%+62713F-HRTimeline
Persistent Asset Partners Ltd11,014$264K0.13%new13F-HRTimeline
Orion Porfolio Solutions, LLC10,768$258K<0.01%new13F-HRTimeline
Sassicaia Capital Advisers LLC10,400$249K0.55%-5,60013F-HRTimeline
Scientech Research LLC10,203$244K0.15%-19,09213F-HRTimeline
China Universal Asset Management Co., L…10,150$243K0.02%+53313F-HRTimeline
ASHFORD CAPITAL MANAGEMENT INC10,000$239K0.03%new13F-HRTimeline
Quinn Opportunity Partners LLC10,000$239K0.01%-97,60013F-HRTimeline
Pavaki Capital Management LLC9,810$235K0.16%13F-HR/ATimeline
Graham Capital Management, L.P.9,013$216K0.01%new13F-HRTimeline
Seven Fleet Capital Management LP8,742$209K0.14%13F-HR/ATimeline
Rangeley Capital, LLC8,500$203K0.18%new13F-HRTimeline
Militia Capital Partners, LPin group Militia Capital Management LLC8,500$203K0.08%-26,50013F-HR/ATimelineGroup
Mraz, Amerine & Associates, Inc.8,495$203K0.03%-82413F-HRTimeline
KLP KAPITALFORVALTNING AS8,400$201K<0.01%013F-HRTimeline
Cetera Investment Advisers8,366$200K<0.01%new13F-HRTimeline
Mitsubishi UFJ Asset Management Co., Lt…in group Mitsubishi UFJ Trust & Bankin…8,098$189K<0.01%-7,35213F-HRTimelineGroup
US BANCORP \DE\in group US BANCORP \DE\6,171$148K<0.01%+5,46613F-HRTimelineGroup
Quantbot Technologies LP5,444$130K<0.01%new13F-HRTimeline
Activest Wealth Management5,000$120K0.02%013F-HRTimeline
Bellevue Group AGin group Bellevue Group AG4,763$114K<0.01%013F-HRTimelineGroup
DEUTSCHE BANK AG\in group DEUTSCHE BANK AG\4,621$111K<0.01%+2,29113F-HRTimelineGroup
Knott David M Jr4,000$95.7K0.04%+2,00013F-HRTimeline
Ensign Peak Advisors, Inc3,650$87.3K<0.01%+65013F-HR/ATimeline
FNY Investment Advisers, LLC2,080$49K0.01%+42613F-HRTimeline
IFP Advisors, Inc1,989$47.6K<0.01%new13F-HRTimeline
Smartleaf Asset Management LLC2,000$47.6K<0.01%new13F-HRTimeline
GF FUND MANAGEMENT CO. LTD.1,223$29.3K<0.01%+4313F-HRTimeline
Torren Management, LLC1,169$28K0.01%13F-HRTimeline
CIBC Private Wealth Group LLCin group CIBC Bancorp USA Inc.850$20.3K<0.01%013F-HRTimelineGroup
Parallel Advisors, LLC848$20.3K<0.01%new13F-HRTimeline
COMERICA BANK637$15.2K<0.01%+23013F-HRTimeline
OSAIC HOLDINGS, INC.in group OSAIC HOLDINGS, INC.587$14K<0.01%+47613F-HRTimelineGroup
JONES FINANCIAL COMPANIES LLLPin group JONES FINANCIAL COMPANIES LLLP418$10K<0.01%-19113F-HRTimelineGroup
Cygnus Capital Advisors, LLC288$7K0.01%13F-HRTimeline
SBI Securities Co., Ltd.280$6.7K<0.01%-85813F-HRTimeline
CWM, LLCin group CWM, LLC247$6K<0.01%013F-HRTimelineGroup
Steward Partners Investment Advisory, L…250$5.98K<0.01%013F-HRTimeline
SIGNATUREFD, LLC249$5.96K<0.01%013F-HRTimeline
Rockefeller Capital Management L.P.in group Rockefeller Capital Managemen…247$5.91K<0.01%-75313F-HR/ATimelineGroup
UMB Bank, n.a.200$4.79K<0.01%013F-HRTimelineThe filing omitted confidential holdings, a later amendment may add them.
ENTRUST FINANCIAL LLC190$4.55K<0.01%13F-HRTimeline
QUADRANT CAPITAL GROUP LLC187$4.47K<0.01%013F-HRTimeline
Allworth Financial LP174$4.16K<0.01%013F-HRTimeline
Daiwa Securities Group Inc.in group Daiwa Securities Group Inc.158$4K<0.01%013F-HRTimelineGroup
State of Wyoming161$3.85K<0.01%new13F-HRTimeline
Farther Finance Advisors, LLC114$2.73K<0.01%new13F-HRTimeline
ORG Partners LLC114$2.72K<0.01%new13F-HRTimeline
EverSource Wealth Advisors, LLCin group EverSource Wealth Advisors, L…109$2.61K<0.01%013F-HRTimelineGroup
TOTH FINANCIAL ADVISORY CORP100$2.39K<0.01%-6513F-HRTimeline
Basecamp Wealth Advisors LLC91$2.18K<0.01%13F-HRTimeline