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Disclosery

13F-HR filed by DIADEMA PARTNERS LP

DIADEMA PARTNERS LP filed this 13F-HR for the quarter ended 2025-12-31, filed 2026-02-17, with 145 holding rows worth $580,539,432.

Accession
0001892688-26-000036
Filer
CIK 2026172
Filed
2026-02-17
Accepted by EDGAR
acceptance time not in the bulk data set
Ingested
Source
SEC quarterly data set

Original filing

13F report for Q4 2025

A holdings report, 145 entries on the cover page, a total value of $580,539,432 stated on the cover page (in dollars after the unit check, H1), rows summing to $580,539,432 with VALUE read as dollars as filed, 13F file number 028-25172. The quarter's positions are built on this report. The resolved quarter.

The information table after summing rows of one CUSIP and put or call (H4), with the CUSIP and issuer name as filed. Values in dollars after the unit check (method).

Issuer as filedCUSIPClassAmountValueValue read asType
Vertex Pharmaceuticals Incorporated92532F100COM88,300$40,031,688dollars as filedcall
SPDR SER TR78464A870S&P BIOTECH250,000$30,482,500dollars as filedput
PRAXIS PRECISION MEDICINES I74006W207COM NEW100,600$29,650,844dollars as filedput
VIKING THERAPEUTICS INC92686J106COM688,900$24,235,502dollars as filedcall
AVIDITY BIOSCIENCES INC COM05370A108Stock328,000$23,658,640dollars as filedcall
INVESCO QQQ TR46090E103COM30,000$18,429,300dollars as filedput
JAZZ PHARMACEUTICALS PLC SHS USDG50871105Stock105,300$17,901,000dollars as filedcall
APOGEE THERAPEUTICS INC COM03770N101Stock211,100$15,933,828dollars as filedcall
BRIDGEBIO PHARMA INC10806X102COM200,000$15,298,000dollars as filedput
TERNS PHARMACEUTICALS INC COM880881107Stock345,880$13,973,552dollars as filed
Johnson & Johnson478160104COM66,444$13,750,586dollars as filed
STRUCTURE THERAPEUTICS INC COMP86366E106EQUITY191,700$13,332,735dollars as filedcall
VIKING THERAPEUTICS INC92686J106COM336,849$11,850,348dollars as filed
VIKING THERAPEUTICS INC92686J106COM316,700$11,141,506dollars as filedput
BRIDGEBIO PHARMA INC10806X102COM139,600$10,678,004dollars as filedcall
Johnson & Johnson478160104COM50,000$10,347,500dollars as filedcall
ABIVAX SA-00370M103SPONSORED ADS75,644$10,200,972dollars as filed
INCYTE CORP COM45337C102Stock100,000$9,877,000dollars as filedput
INSMED INC COM PAR $.01457669307Stock52,800$9,189,312dollars as filedcall
CAPRICOR THERAPEUTICS INC14070B309COMMON STOCK312,300$9,012,978dollars as filedcall
BIOMARIN PHARMACEUTICAL INC09061G101COM146,361$8,698,234dollars as filed
IONIS PHARMACEUTICALS INC COM462222100Stock106,200$8,401,482dollars as filedcall
REGENERON PHARMACEUTICALS COM75886F107Stock10,300$7,950,261dollars as filed
Indivior PLCG4766E116Common Stock220,300$7,904,364dollars as filedcall
UNIQURE NVN90064101SHS301,800$7,222,074dollars as filedput
ROIVANT SCIENCES LTDG76279101SHS318,700$6,915,790dollars as filedput
OCULAR THERAPEUTIX INC67576A100COM545,200$6,618,728dollars as filedcall
ZYMEWORKS INC98985Y108COM240,600$6,334,998dollars as filedcall
CRISPR THERAPEUTICS AG NAMEN AKTH17182108Stock112,700$5,909,988dollars as filedcall
CAPRICOR THERAPEUTICS INC14070B309COMMON STOCK200,000$5,772,000dollars as filedput
BRIDGEBIO PHARMA INC10806X102COM70,000$5,354,300dollars as filed
UNITED THERAPEUTICS CORP DEL COM91307C102Stock10,000$4,872,500dollars as filed
CORCEPT THERAPEUTICS INC218352102COM134,800$4,691,040dollars as filedput
COGENT BIOSCIENCES INC19240Q201COM131,852$4,683,383dollars as filed
CAPRICOR THERAPEUTICS INC14070B309COMMON STOCK158,075$4,562,045dollars as filed
Vertex Pharmaceuticals Incorporated92532F100COM10,000$4,533,600dollars as filed
ANI PHARMACEUTICALS INC00182C103COM53,354$4,211,765dollars as filed
REGENERON PHARMACEUTICALS COM75886F107Stock5,000$3,859,350dollars as filedcall
TG THERAPEUTICS INC COM88322Q108Stock123,283$3,675,066dollars as filed
BIOAGE LABS INC COM09077V100Stock271,164$3,587,500dollars as filed
CORCEPT THERAPEUTICS INC218352102COM97,445$3,391,086dollars as filed
MANNKIND CORP COM NEW56400P706Stock552,300$3,131,541dollars as filedcall
RECURSION PHARMACEUTICALS IN75629V104CL A741,900$3,034,371dollars as filedcall
TG THERAPEUTICS INC COM88322Q108Stock100,000$2,981,000dollars as filedput
TENAX THERAPEUTICS INC88032L605COM NEW243,170$2,964,242dollars as filed
REVOLUTION MEDICINES INC COM76155X100Stock37,020$2,948,643dollars as filed
INTELLIA THERAPEUTICS INC45826J105COM316,900$2,848,931dollars as filedput
GOSSAMER BIO INC COM38341P102Stock877,100$2,719,010dollars as filedcall
NOVO-NORDISK A S ADR670100205ADR53,100$2,701,728dollars as filedput
Arbutus Biopharma Corp03879J100Common Shares, without par value548,600$2,638,766dollars as filedcall
TERNS PHARMACEUTICALS INC COM880881107Stock64,700$2,613,880dollars as filedcall
SOLENO THERAPEUTICS INC834203309COM53,100$2,458,530dollars as filedcall
IMMUNOCORE HLDGS PLC ADS45258D105ADR70,300$2,440,113dollars as filed
OLEMA PHARMACEUTICALS INC68062P106COM96,100$2,402,500dollars as filedcall
IRONWOOD PHARMACEUTICALS INC46333X108COMMON STOCK683,611$2,303,769dollars as filed
ULTRAGENYX PHARMACEUTICAL IN90400D108COM100,000$2,300,000dollars as filedcall
BIOHAVEN LTDG1110E107COM200,000$2,258,000dollars as filedcall
CENTESSA PHARMACEUTICALS PLC152309100SPONSORED ADS90,000$2,250,900dollars as filed
REPLIMUNE GROUP INC76029N106COMMON STOCK230,997$2,245,291dollars as filed
AQUESTIVE THERAPEUTICS INC COM03843E104Stock337,700$2,181,542dollars as filedput
Eli Lilly and Company532457108COM2,000$2,149,360dollars as filed
ALNYLAM PHARMACEUTICALS INC COM02043Q107Stock5,341$2,123,849dollars as filed
TECTONIC THERAPEUTIC INC878972108COMMON STOCK100,600$2,098,516dollars as filedcall
LIPOCINE INC NEW53630X203COM NEW260,939$2,095,340dollars as filed
PROTAGONIST THERAPEUTICS74366E102COM22,700$1,982,618dollars as filed
TRAVERE THERAPEUTICS INC89422G107COM50,300$1,921,963dollars as filedput
INTELLIA THERAPEUTICS INC45826J105COM212,400$1,909,476dollars as filedcall
RELMADA THERAPEUTICS INC75955J402COMMON STOCK389,395$1,880,778dollars as filed
CORMEDIX INC COM21900C308Stock159,000$1,849,170dollars as filedput
Ventyx Biosciences Inc92332V107Common Stock200,000$1,806,000dollars as filed
ALTIMMUNE INC02155H200COM NEW491,800$1,775,398dollars as filedcall
VANDA PHARMACEUTICALS INC921659108COM200,000$1,764,000dollars as filedcall
ANNEXON INC03589W102COM350,000$1,757,000dollars as filed
MANNKIND CORP COM NEW56400P706Stock302,000$1,712,340dollars as filed
SELLAS LIFE SCIENCES GROUP I81642T209COM NEW424,900$1,601,873dollars as filedcall
INVENTIVA SA46124U107ADS334,251$1,554,267dollars as filed
ANNEXON INC03589W102COM309,100$1,551,682dollars as filedcall
LEGEND BIOTECH CORP52490G102SPONSORED ADS69,000$1,500,060dollars as filedcall
BIOCRYST PHARMACEUTICALS INC COM09058V103Stock190,928$1,489,238dollars as filed
ARDELYX INC039697107COM252,198$1,470,314dollars as filed
ASCENDIS PHARMA A/S DKK 1.0 AD04351P101SPONSORED ADR6,840$1,458,562dollars as filed
AQUESTIVE THERAPEUTICS INC COM03843E104Stock211,100$1,363,706dollars as filedcall
XERIS BIOPHARMA HOLDINGS INC98422E103COM170,568$1,338,959dollars as filed
RIGEL PHARMACEUTICALS INC766559702COMMON STOCK30,000$1,284,900dollars as filed
SOLENO THERAPEUTICS INC834203309COM26,892$1,245,100dollars as filed
PACIRA BIOSCIENCES INC COM695127100Stock48,025$1,242,887dollars as filed
TREVI THERAPEUTICS INC COM89532M101Stock97,184$1,216,744dollars as filed
MAPLIGHT THERAPEUTICS INC56565P103COMMON STOCK63,791$1,120,489dollars as filed
UNIQURE NVN90064101SHS45,000$1,076,850dollars as filed
VAXCYTE INC COM92243G108Stock22,972$1,059,928dollars as filed
ENANTA PHARMACEUTICALS INC29251M106COM65,138$1,027,226dollars as filed
PROTHENA CORP PLC SHSG72800108Stock106,539$1,017,447dollars as filed
MONTE ROSA THERAPEUTICS INC61225M102COM62,281$976,566dollars as filed
DESIGN THERAPEUTICS INC25056L103COM100,320$941,002dollars as filed
INOVIO PHARMACEUTICALS I45773H409COMMON STOCK533,682$928,607dollars as filed
MINERALYS THERAPEUTICS INC603170101COM25,000$907,250dollars as filed
MEREO BIOPHARMA GROUP PLC589492107CMN1,999,500$833,192dollars as filedcall
KODIAK SCIENCES INC50015M109COM29,600$827,616dollars as filedcall
AYTU BIOPHARMA INC054754858COM305,788$795,049dollars as filed
EVOLUS INC30052C107COM118,800$790,020dollars as filedcall
PELTHOS THERAPEUTICS INC171126204COM SHS25,000$775,000dollars as filed
LIQUIDIA CORPORATION COM NEW53635D202Stock21,881$754,676dollars as filed
EDGEWISE THERAPEUTICS INC28036F105COM30,000$744,450dollars as filed
VIRIDIAN THERAPEUTICS INC92790C104COM21,114$657,068dollars as filed
EDITAS MEDICINE INC28106W103COM318,700$653,335dollars as filedcall
MOONLAKE IMMUNOTHERAPEUTICS CLASS A ORD61559X104Stock47,200$622,096dollars as filedcall
Indivior PLCG4766E116Common Stock17,320$621,442dollars as filed
VIR BIOTECHNOLOGY INC92764N102COM100,000$603,000dollars as filed
LIGAND PHARMACEUTICALS INC53220K504COM NEW2,987$564,752dollars as filed
ZYMEWORKS INC98985Y108COM21,400$563,462dollars as filedput
UPSTREAM BIO INC91678A107COMMON STOCK20,500$556,575dollars as filed
STOKE THERAPEUTICS INC86150R107COM17,181$545,325dollars as filed
EQUILLIUM INC29446K106COM347,393$538,459dollars as filed
VIR BIOTECHNOLOGY INC92764N102COM89,200$537,876dollars as filedcall
CENTESSA PHARMACEUTICALS PLC152309100SPONSORED ADS21,100$527,711dollars as filedcall
UROGEN PHARMA LTDM96088105COMMON STOCK21,810$510,790dollars as filed
ANAVEX LIFE SCIENCES CORP032797300COM NEW140,600$500,536dollars as filedcall
IMMUNOME INC45257U108COM22,500$483,300dollars as filed
BLACK DIAMOND THERAPEUTICS I09203E105COM190,400$462,672dollars as filedcall
JANUX THERAPEUTICS INC47103J105COM30,000$414,000dollars as filedcall
CORVUS PHARMACEUTICALS INC221015100COM53,100$408,870dollars as filedput
PALISADE BIO INC696389402COMMON STOCK166,049$390,215dollars as filed
PROQR THERAPEUTICS NVN71542109SHS EURO167,532$338,415dollars as filed
BIOAGE LABS INC COM09077V100Stock22,600$298,998dollars as filedcall
HARMONY BIOSCIENCES HLDGS IN413197104COM7,500$280,650dollars as filed
AARDVARK THERAPEUTICS INC002942100COM15,882$208,451dollars as filed
PUMA BIOTECHNOLOGY INC74587V107COMMON STOCK33,800$201,110dollars as filedcall
NEUPHORIA THERAPEUTICS INC64136E102COM50,000$194,000dollars as filed
PLIANT THERAPEUTICS INC729139105COM144,914$176,795dollars as filed
INOVIO PHARMACEUTICALS I45773H409COMMON STOCK100,000$174,000dollars as filedcall
BEONE MEDICINES LTD SPONSORED ADS07725L102ADR7,500$172,784dollars as filed
FOGHORN THERAPEUTICS INC344174107COMMON STOCK30,630$165,402dollars as filed
TALPHERA INC00444T209COM NEW136,923$156,092dollars as filed
Reviva Pharmaceuticals Holdings Inc76152G100Common Stock500,000$139,500dollars as filedcall
PURETECH HEALTH PLC746237106ADS7,442$123,835dollars as filed
LYELL IMMUNOPHARMA INC COM NEW55083R203Stock3,800$116,964dollars as filedput
INHIBRX BIOSCIENCES INC45720N103COM1,299$102,621dollars as filed
EDESA BIOTECH INC27966L306COM NEW54,025$76,716dollars as filed
VISTAGEN THERAPEUTICS INC92840H400COM106,500$70,492dollars as filedcall
VISTAGEN THERAPEUTICS INC92840H400COM100,000$66,190dollars as filed
FILANA THERAPEUTICS INC14817C107CMN10,600$20,988dollars as filedput
ATYR PHARMA INC002120202COM NEW15,500$12,138dollars as filedcall
ATYR PHARMA INC002120202COM NEW11,800$9,241dollars as filedput
JADE BIOSCIENCES INC008064206COM NEW1,046$2,972dollars as filedput
Applied Therapeutics Inc03828A101Common Stock20,200$2,020dollars as filedcall

Amendment chain

FilingRoleFiledAcceptedIngested
13F-HR 0001892688-26-000036this filing2026-02-17acceptance time not in the bulk data set