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Disclosery

QURE UNIQURE NV

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SHS (common), issuer CIK 1590560

139 managers (144 13F filers) reported a position in QURE shares at 2025-06-30, 52,961,222 shares in all. 32 filers opened a position and 30 filers sold out during the quarter.

Managers
139
13F filers
144
New
32
Added
43
Reduced
48
Sold out
30
Shares held by filers
52,961,222

Shares held by filers adds up every 13F filer's report, so a share reported by a parent and by its subsidiary counts twice (H9). Managers counts each filer group once.

13D and 13G filers

No 13D or 13G on this security in the data. Structured 13D/G data starts 2024-12-18.

Insider trades

No Form 4 transaction on this security in the data.

13F holders, Q2 2025

Filers in the available 13F reports with a share position at 2025-06-30, filer groups collapsed to one row (method), largest first. Options and principal amounts are left out. A group row states no % of portfolio, since each member reports its own portfolio: the members' percents are listed under it. A value about 1,000 times or 1/1,000 of the price other filers imply is shown as filed but neither ranks the row nor enters a sum.

HolderSharesValue% of portfolioChangeSource
RTW INVESTMENTS, LP5,158,231$71.9M1.02%+892,80313F-HRTimeline
EcoR1 Capital, LLC3,988,971$55.6M3.3%013F-HRTimeline
Vestal Point Capital, LP3,700,000$51.6M2.72%-1,092,57213F-HRTimeline
Avoro Capital Advisors LLC3,625,000$50.5M0.88%+1,450,00013F-HRTimeline
Aberdeen Group plcin group Aberdeen Group plc2,750,714$38.3M0.07%+535,16313F-HRTimelineGroup
Jefferies Financial Group Inc.in group Jefferies Financial Group Inc.2,095,931$29.2M0.48%new13F-HRTimelineGroup
Nantahala Capital Management, LLCin group Nantahala Capital Management,…2,051,852$28.6M2.02%-704,11013F-HRTimelineGroup
JPMORGAN CHASE & COin group JPMORGAN CHASE & CO1,807,685$25.2M<0.01%+1,491,48613F-HRTimelineGroup
FRANKLIN RESOURCES INCin group Franklin Resources1,605,515$22.4M0.01%-382,17313F-HRTimelineGroup
TWO SIGMA INVESTMENTS, LPgroup of 2 filers holding1,600,660$22.3M+15,667Timeline
Sofinnova Investments, Inc.1,558,356$21.7M1.48%+1,012,58513F-HRTimeline
Integral Health Asset Management, LLC1,350,000$18.8M1.76%+100,00013F-HRTimeline
BlackRock, Inc.in group BlackRock, Inc.1,333,663$18.6M<0.01%-103,31813F-HRTimelineGroup
683 Capital Management, LLCin group 683 Capital Management, LLC1,285,000$17.9M1.82%-265,00013F-HRTimelineGroup
FMR LLCin group FMR LLC1,184,362$16.5M<0.01%-16,58213F-HRTimelineGroup
STATE STREET CORPin group STATE STREET CORP1,142,810$15.9M<0.01%-86,77913F-HRTimelineGroup
VANGUARD GROUP INCgroup of 2 filers holding985,442$13.7M+26,330Timeline
MORGAN STANLEYin group MORGAN STANLEY908,283$12.7M<0.01%+304,76713F-HRTimelineGroup
Boxer Capital Management, LLCin group Boxer Capital Management, LLC899,500$12.5M6.31%+149,50013F-HR/ATimelineGroup
AMERIPRISE FINANCIAL INCin group AMERIPRISE FINANCIAL INC761,948$10.6M<0.01%+212,21813F-HRTimelineGroup
MACQUARIE GROUP LTDin group MACQUARIE GROUP LTD706,166$9.84M0.01%013F-HRTimelineGroup
SCHRODER INVESTMENT MANAGEMENT GROUP693,283$9.66M0.01%-496,83813F-HRTimeline
GEODE CAPITAL MANAGEMENT, LLCin group GEODE CAPITAL MANAGEMENT, LLC603,210$8.41M<0.01%-7,76113F-HRTimelineGroup
STEMPOINT CAPITAL LP572,615$7.98M2.57%-158,42413F-HRTimeline
CITADEL ADVISORS LLCin group CITADEL ADVISORS LLC555,865$7.75M0.01%-229,45513F-HRTimelineGroup
Balyasny Asset Management L.P.in group Balyasny Asset Management536,968$7.49M0.02%+512,04013F-HRTimelineGroup
Pale Fire Capital SEin group Pale Fire Capital529,798$7.39M0.77%+67,43913F-HRTimelineGroup
BNP PARIBAS FINANCIAL MARKETSin group BNP PARIBAS FINANCIAL MARKETS503,672$7.02M0.01%+22,22213F-HRTimelineGroup
Privium Fund Management B.V.447,486$6.26M1.35%-131,65313F-HRTimeline
Parkman Healthcare Partners LLC443,422$6.18M0.72%+239,58913F-HRTimeline
Catalio Capital Management, LPin group Catalio Capital Management, LP417,443$5.82M1.22%-412,88213F-HRTimelineGroup
ROYAL BANK OF CANADAin group ROYAL BANK OF CANADA391,614$5.46M<0.01%+342,28313F-HR/ATimelineGroup
UBS Group AGgroup of 2 filers holding374,244$5.22M+147,348Timeline
GOLDMAN SACHS GROUP INCin group GOLDMAN SACHS GROUP INC356,463$4.97M<0.01%+96,82613F-HRTimelineGroup
Bank of New York Mellon Corpin group Bank of New York Mellon Corp348,328$4.86M<0.01%new13F-HRTimelineGroup
CHARLES SCHWAB INVESTMENT MANAGEMENT INCin group Charles Schwab Trust Co292,931$4.08M<0.01%+12,93213F-HRTimelineGroup
MARSHALL WACE, LLPin group MARSHALL WACE, LLP222,979$3.11M<0.01%+163,74913F-HRTimelineGroup
Avidity Partners Management LP207,000$2.89M0.58%-129,20013F-HRTimeline
SILVERARC CAPITAL MANAGEMENT, LLCin group SILVERARC CAPITAL MANAGEMENT,…202,565$2.82M0.58%-83513F-HRTimelineGroup
Caption Management, LLC176,911$2.47M0.23%+156,55213F-HRTimeline
Squarepoint Ops LLCin group Squarepoint Ops LLC176,002$2.45M0.01%-2,33013F-HR/ATimelineGroup
Woodline Partners LP175,806$2.45M0.01%013F-HRTimeline
MOORE CAPITAL MANAGEMENT, LP175,000$2.44M0.05%+25,00013F-HRTimeline
PFM Health Sciences, LP174,331$2.43M0.21%-425,63613F-HRTimeline
Invesco Ltd.in group Invesco Ltd.166,799$2.33M<0.01%-318,50613F-HRTimelineGroup
Hudson Bay Capital Management LPin group Hudson Bay Capital Management…148,182$2.07M0.01%-3,51813F-HR/ATimelineGroup
BANK OF AMERICA CORP /DE/in group BANK OF AMERICA CORP /DE/141,810$1.98M<0.01%-239,04213F-HRTimelineGroup
JENNISON ASSOCIATES LLC140,060$1.95M<0.01%new13F-HRTimeline
Affinity Asset Advisors, LLC135,000$1.88M0.28%-265,00013F-HRTimeline
Schonfeld Strategic Advisors LLC134,948$1.88M0.01%+92,80113F-HRTimeline
MILLENNIUM MANAGEMENT LLCin group MILLENNIUM MANAGEMENT LLC132,664$1.85M<0.01%-133,00213F-HRTimelineGroup
NORTHERN TRUST CORPin group NORTHERN TRUST CORP125,685$1.75M<0.01%+26,78913F-HRTimelineGroup
Voss Capital, LP125,000$1.74M0.12%new13F-HRTimeline
Ikarian Capital, LLCin group Ikarian Capital, LLC119,986$1.67M0.55%new13F-HRTimelineGroup
Russell Investments Group, Ltd.in group Russell Investments Group, Lt…106,490$1.48M<0.01%-197,14213F-HRTimelineGroup
Point72 Asset Management, L.P.in group Point72 Asset Management, L.P.105,939$1.48M<0.01%-24,13613F-HRTimelineGroup
Shay Capital LLC99,383$1.39M0.32%+17,53413F-HRTimeline
Birchview Capital, LP98,697$1.38M1.37%+10,00013F-HRTimeline
SG Americas Securities, LLC94,759$1.32M0.01%new13F-HRTimeline
Verition Fund Management LLC92,591$1.29M0.01%-3,94313F-HRTimeline
BARCLAYS PLCin group BARCLAYS PLC89,014$1.24M<0.01%+21,27013F-HR/ATimelineGroup
SUSQUEHANNA INTERNATIONAL GROUP, LLPgroup of 2 filers holding86,817$1.21M+6,936Timeline
Diamond Hill Capital Management, LLC (I…82,653$1.15M0.01%013F-HRTimeline
Swiss National Bank77,500$1.08M<0.01%new13F-HRTimeline
SummitTX Capital, L.P.77,495$1.08M0.05%new13F-HRTimeline
Monaco Asset Management SAM70,000$976K0.37%-5,00013F-HRTimeline
Rafferty Asset Management, LLC68,807$959K<0.01%-13,78213F-HRTimeline
VOYA INVESTMENT MANAGEMENT LLCin group VOYA INVESTMENT MANAGEMENT LLC67,260$938K<0.01%+18,20513F-HRTimelineGroup
STIFEL FINANCIAL CORPin group STIFEL FINANCIAL CORP66,981$934K<0.01%+11,21313F-HRTimelineGroup
SIMPLEX TRADING, LLC64,259$895K0.02%+16,73513F-HRTimeline
GROUP ONE TRADING LLC63,681$888K0.03%+60,13613F-HRTimeline
OCONNOR, A Distinct Business Unit of UB…63,475$885K0.02%-51,41413F-HRTimelineThe filing omitted confidential holdings, a later amendment may add them.
Y-Intercept (Hong Kong) Ltd62,538$872K0.02%new13F-HRTimeline
Main Management ETF Advisors, LLCin group Main Management ETF Advisors,…56,420$786K0.03%+91213F-HRTimelineGroup
SECTORAL ASSET MANAGEMENT INC55,450$773K0.51%-2,10013F-HRTimeline
JANE STREET GROUP, LLCin group JANE STREET GROUP, LLC50,430$703K<0.01%+13,03413F-HRTimelineGroup
Centiva Capital, LP50,000$697K0.05%new13F-HRTimeline
Headlands Technologies LLC42,444$592K0.07%+31,94813F-HRTimeline
RAYMOND JAMES FINANCIAL INCin group RAYMOND JAMES FINANCIAL INC40,289$562K<0.01%-1,89713F-HRTimelineGroup
Massar Capital Management, LP40,000$558K0.42%013F-HR/ATimeline
Mirae Asset Global Investments Co., Ltd.group of 2 filers holding39,328$548K-33,508Timeline
CALIFORNIA STATE TEACHERS RETIREMENT SY…38,707$540K<0.01%new13F-HRTimeline
Legal & General Group Plcin group Legal & General Group Plc35,621$497K<0.01%new13F-HRTimelineGroup
Aquatic Capital Management LLC35,262$492K0.01%+24,67213F-HRTimeline
BOOTHBAY FUND MANAGEMENT, LLC33,612$469K0.01%-4,16013F-HRTimeline
Hennion & Walsh Asset Management, Inc.30,369$423K0.02%new13F-HRTimeline
HRT FINANCIAL LP28,420$396K<0.01%new13F-HRTimeline
Engineers Gate Manager LP27,904$389K<0.01%new13F-HRTimeline
D. E. Shaw & Co., Inc.in group D. E. Shaw & Co., Inc.27,531$384K<0.01%new13F-HRTimelineGroup
DNB Asset Management ASin group DNB Asset Management AS25,159$351K<0.01%-16113F-HRTimelineGroup
Militia Capital Partners, LPin group Militia Capital Management LLC22,200$309K0.15%new13F-HR/ATimelineGroup
CITIGROUP INCin group CITIGROUP INC20,482$286K<0.01%-73,71513F-HRTimelineGroup
Virtu Financial LLCin group Virtu Financial LLC19,850$277K0.01%new13F-HRTimelineGroup
Zurcher Kantonalbank (Zurich Cantonalba…19,804$276K<0.01%+17,34813F-HRTimeline
Bellevue Group AGin group Bellevue Group AG19,610$273K0.01%-2,89013F-HRTimelineGroup
ALGERT GLOBAL LLC19,340$270K0.01%new13F-HR/ATimeline
JANUS HENDERSON GROUP PLCin group Janus Henderson16,900$236K<0.01%new13F-HRTimelineGroup
Mitsubishi UFJ Asset Management Co., Lt…in group Mitsubishi UFJ Trust & Bankin…15,420$215K<0.01%new13F-HRTimelineGroup
FARALLON CAPITAL MANAGEMENT, L.L.C.14,000$195K<0.01%013F-HRTimelineThe filing omitted confidential holdings, a later amendment may add them.
PROFUND ADVISORS LLC13,716$191K0.01%-2,63213F-HRTimeline
WOLVERINE TRADING, LLC13,791$191K<0.01%+2,95613F-HRTimeline
Total Clarity Wealth Management, Inc.12,450$174K0.05%-2,90013F-HRTimeline
Clear Harbor Asset Management, LLC12,250$171K0.01%-1,25013F-HRTimeline
ARIZONA STATE RETIREMENT SYSTEM11,824$165K<0.01%new13F-HRTimeline
China Universal Asset Management Co., L…10,996$153K0.01%-57813F-HRTimeline
WELLS FARGO & COMPANY/MNin group WELLS FARGO & COMPANY/MN10,942$153K<0.01%-1,38813F-HRTimelineGroup
TEACHER RETIREMENT SYSTEM OF TEXAS10,808$151K<0.01%new13F-HRTimeline
Corient Private Wealth LPin group Corient Private Wealth LP10,630$148K<0.01%013F-HR/ATimelineGroup
KLP KAPITALFORVALTNING AS8,400$117K<0.01%new13F-HRTimeline
Tower Research Capital LLC (TRC)in group Tower Research Capital LLC (T…7,085$98.8K<0.01%+5,53813F-HRTimelineGroup
Virtus Investment Advisers, LLCin group Virtus Investment Advisers, L…5,881$82K0.03%-5,02513F-HRTimelineGroup
Activest Wealth Management5,000$69.7K0.02%013F-HRTimeline
Future Financial Wealth Managment LLC4,000$55.8K0.04%013F-HRTimeline
SBI Securities Co., Ltd.1,730$24.1K<0.01%+1,00313F-HRTimeline
Point72 Hong Kong Ltd1,465$20.4K<0.01%new13F-HRTimeline
GF FUND MANAGEMENT CO. LTD.1,248$17.4K<0.01%013F-HRTimeline
TORONTO DOMINION BANKin group TORONTO DOMINION BANK1,200$16.7K<0.01%new13F-HRTimelineGroup
Covestor Ltd1,183$16K0.01%new13F-HRTimeline
FNY Investment Advisers, LLC936$13K0.01%new13F-HRTimeline
NATIONAL BANK OF CANADA /FI/in group NATIONAL BANK OF CANADA /FI/779$10.8K<0.01%-18813F-HR/ATimelineGroup
US BANCORP \DE\in group US BANCORP \DE\737$10.3K<0.01%+6113F-HRTimelineGroup
Brooklyn Investment Group447$6.23K<0.01%new13F-HR/ATimeline
Wilmington Savings Fund Society, FSB352$4.91K<0.01%013F-HRTimeline
SALEM INVESTMENT COUNSELORS INC300$4.18K<0.01%013F-HR/ATimeline
SIGNATUREFD, LLC249$3.47K<0.01%-27513F-HRTimeline
Versant Capital Management, Inc249$3.47K<0.01%-7913F-HRTimeline
COMERICA BANK244$3.4K<0.01%new13F-HRTimeline
Caitong International Asset Management …231$3.22K<0.01%+13513F-HRTimeline
CWM, LLCin group CWM, LLC234$3K<0.01%013F-HRTimelineGroup
TOTH FINANCIAL ADVISORY CORP165$2.3K<0.01%013F-HRTimeline
Allworth Financial LP164$2.29K<0.01%013F-HRTimeline
Daiwa Securities Group Inc.in group Daiwa Securities Group Inc.158$2K<0.01%013F-HRTimelineGroup
OSAIC HOLDINGS, INC.in group OSAIC HOLDINGS, INC.111$1.55K<0.01%-7013F-HR/ATimelineGroup
EverSource Wealth Advisors, LLCin group EverSource Wealth Advisors, L…109$1.52K<0.01%013F-HRTimelineGroup
JONES FINANCIAL COMPANIES LLLPin group JONES FINANCIAL COMPANIES LLLP100$1.39K<0.01%013F-HRTimelineGroup
LANARK FINANCIAL, INC.3$1K<0.01%new13F-HRTimeline
First Horizon Advisors, Inc.3$42<0.01%-813F-HRTimeline
HUNTINGTON NATIONAL BANKin group HUNTINGTON NATIONAL BANK2$28<0.01%013F-HRTimelineGroup
CONCOURSE FINANCIAL GROUP SECURITIES, I…0$0013F-HRTimelineValue filed as zero, left out of ratios. Amount filed as zero, left out of ratios.