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Disclosery

QURE UNIQURE NV

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SHS (common), issuer CIK 1590560

214 managers (219 13F filers) reported a position in QURE shares at 2025-09-30, 55,356,169 shares in all. 96 filers opened a position and 20 filers sold out during the quarter.

Managers
214
13F filers
219
New
96
Added
48
Reduced
62
Sold out
20
Shares held by filers
55,356,169

Shares held by filers adds up every 13F filer's report, so a share reported by a parent and by its subsidiary counts twice (H9). Managers counts each filer group once.

13D and 13G filers

No 13D or 13G on this security in the data. Structured 13D/G data starts 2024-12-18.

Insider trades

No Form 4 transaction on this security in the data.

13F holders, Q3 2025

Filers in the available 13F reports with a share position at 2025-09-30, filer groups collapsed to one row (method), largest first. Options and principal amounts are left out. A group row states no % of portfolio, since each member reports its own portfolio: the members' percents are listed under it. A value about 1,000 times or 1/1,000 of the price other filers imply is shown as filed but neither ranks the row nor enters a sum.

HolderSharesValue% of portfolioChangeSource
FMR LLCin group FMR LLC6,059,574$354M0.02%+4,875,21213F-HRTimelineGroup
Avoro Capital Advisors LLC4,444,444$259M3.36%+819,44413F-HRTimeline
RTW INVESTMENTS, LP4,424,968$258M3.18%-733,26313F-HRTimeline
EcoR1 Capital, LLC3,988,971$233M11.17%013F-HRTimeline
Aberdeen Group plcin group Aberdeen Group plc2,939,743$172M0.27%+189,02913F-HRTimelineGroup
FRANKLIN RESOURCES INCin group Franklin Resources1,988,581$116M0.03%+383,06613F-HRTimelineGroup
BlackRock, Inc.in group BlackRock, Inc.1,446,099$84.4M<0.01%+112,43613F-HRTimelineGroup
STATE STREET CORPin group STATE STREET CORP1,444,010$84.3M<0.01%+301,20013F-HRTimelineGroup
TWO SIGMA INVESTMENTS, LPgroup of 2 filers holding1,307,038$76.3M-293,622Timeline
FRED ALGER MANAGEMENT, LLCin group FRED ALGER MANAGEMENT, LLC1,290,391$75.3M0.29%new13F-HRTimelineGroup
JPMORGAN CHASE & COin group JPMORGAN CHASE & CO1,149,351$67.1M<0.01%-658,33413F-HR/ATimelineGroup
VANGUARD GROUP INCgroup of 2 filers holding1,137,547$66.4M+152,105Timeline
683 Capital Management, LLCin group 683 Capital Management, LLC1,070,000$62.5M5.67%-215,00013F-HRTimelineGroup
Nantahala Capital Management, LLCin group Nantahala Capital Management,…1,007,492$58.8M3.63%-1,044,36013F-HRTimelineGroup
JENNISON ASSOCIATES LLC999,484$58.3M0.03%+859,42413F-HRTimeline
PRICE T ROWE ASSOCIATES INC /MD/913,180$53.3M0.01%new13F-HRTimeline
Eversept Partners, LP877,373$51.2M3.92%new13F-HRTimeline
Boxer Capital Management, LLCin group Boxer Capital Management, LLC800,000$46.7M14.88%-99,50013F-HR/ATimelineGroup
GEODE CAPITAL MANAGEMENT, LLCin group GEODE CAPITAL MANAGEMENT, LLC721,652$42.1M<0.01%+118,44213F-HRTimelineGroup
GOLDMAN SACHS GROUP INCin group GOLDMAN SACHS GROUP INC662,208$38.7M0.01%+305,74513F-HRTimelineGroup
Artia Global Partners LP658,839$38.5M6.77%new13F-HR/ATimeline
Integral Health Asset Management, LLC600,000$35M2.55%-750,00013F-HRTimeline
FARALLON CAPITAL MANAGEMENT, L.L.C.565,000$33M0.19%+551,00013F-HR/ATimeline
STEMPOINT CAPITAL LP522,155$30.5M6.15%-50,46013F-HRTimeline
Nationale-Nederlanden Powszechne Towarz…521,677$30.5M2.35%new13F-HRTimeline
Deep Track Capital, LP483,092$28.2M0.79%new13F-HRTimeline
ORBIMED ADVISORS LLCin group ORBIMED ADVISORS LLC458,500$26.8M0.64%new13F-HRTimelineGroup
Caption Management, LLC458,300$26.8M1.56%+281,38913F-HRTimeline
SILVERARC CAPITAL MANAGEMENT, LLCin group SILVERARC CAPITAL MANAGEMENT,…455,000$26.6M3.84%+252,43513F-HRTimelineGroup
CITADEL ADVISORS LLCin group CITADEL ADVISORS LLC429,710$25.1M0.02%-126,15513F-HRTimelineGroup
Darwin Global Management, Ltd.in group Darwin Global Management, Ltd.400,000$23.8M0.66%new13F-HRTimelineGroup
Privium Fund Management B.V.386,000$22.5M4.05%-61,48613F-HRTimeline
BNP PARIBAS FINANCIAL MARKETSin group BNP PARIBAS FINANCIAL MARKETS385,609$22.5M0.02%-118,06313F-HRTimelineGroup
CHARLES SCHWAB INVESTMENT MANAGEMENT INCin group Charles Schwab Trust Co357,685$20.9M<0.01%+64,75413F-HRTimelineGroup
Parkman Healthcare Partners LLC345,356$20.2M2.21%-98,06613F-HRTimeline
Balyasny Asset Management L.P.in group Balyasny Asset Management333,235$19.5M0.04%-203,73313F-HRTimelineGroup
MORGAN STANLEYin group MORGAN STANLEY321,501$18.8M<0.01%-586,78213F-HR/ATimelineGroup
Affinity Asset Advisors, LLC300,000$17.5M1.63%+165,00013F-HRTimeline
Logos Global Management LP300,000$17.5M1.73%new13F-HRTimeline
BANK OF AMERICA CORP /DE/in group BANK OF AMERICA CORP /DE/295,131$17.2M<0.01%+153,32113F-HR/ATimelineGroup
Catalio Capital Management, LPin group Catalio Capital Management, LP282,940$16.5M3.05%-134,50313F-HRTimelineGroup
Siren, L.L.C.in group Siren, L.L.C.275,200$16.1M0.63%new13F-HRTimelineGroup
MACQUARIE GROUP LTDin group MACQUARIE GROUP LTD258,211$15.1M0.02%-447,95513F-HRTimelineGroup
SUSQUEHANNA INTERNATIONAL GROUP, LLPgroup of 3 filers holding255,088$14.9M+168,271Timeline
Point72 Asset Management, L.P.in group Point72 Asset Management, L.P.254,082$14.8M0.03%+148,14313F-HRTimelineGroup
Vestal Point Capital, LP225,000$13.1M0.6%-3,475,00013F-HRTimeline
ROYAL BANK OF CANADAin group ROYAL BANK OF CANADA211,413$12.3M<0.01%-180,20113F-HRTimelineGroup
UBS Group AGgroup of 2 filers holding204,989$12M-169,255Timeline
RA CAPITAL MANAGEMENT, L.P.in group RA CAPITAL MANAGEMENT, L.P.200,000$11.7M0.14%new13F-HRTimelineGroup
Soleus Capital Management, L.P.200,000$11.7M0.62%new13F-HRTimeline
MILLENNIUM MANAGEMENT LLCin group MILLENNIUM MANAGEMENT LLC191,600$11.2M0.01%+58,93613F-HRTimelineGroup
Schonfeld Strategic Advisors LLC188,197$11M0.08%+53,24913F-HRTimeline
Squarepoint Ops LLCin group Squarepoint Ops LLC181,902$10.6M0.02%+5,90013F-HRTimelineGroup
LORD, ABBETT & CO. LLC176,025$10.3M0.03%new13F-HRTimeline
AMERIPRISE FINANCIAL INCin group AMERIPRISE FINANCIAL INC158,943$9.28M<0.01%-603,00513F-HRTimelineGroup
NORTHERN TRUST CORPin group NORTHERN TRUST CORP152,437$8.9M<0.01%+26,75213F-HRTimelineGroup
Walleye Capital LLCgroup of 2 filers holding150,230$8.77MnewTimeline
Russell Investments Group, Ltd.in group Russell Investments Group, Lt…149,851$8.75M0.01%+43,36113F-HRTimelineGroup
BOONE CAPITAL MANAGEMENT LLC147,317$8.6M2.82%new13F-HRTimeline
GROUP ONE TRADING LLC140,227$8.19M0.24%+76,54613F-HRTimeline
Sofinnova Investments, Inc.136,862$7.99M0.49%-1,421,49413F-HRTimeline
ADAR1 Capital Management, LLCin group ADAR1 Capital Management, LLC133,316$7.78M0.77%new13F-HRTimelineGroup
Woodline Partners LP130,615$7.62M0.04%-45,19113F-HRTimeline
Rosalind Advisors, Inc.125,000$7.3M2.58%new13F-HRTimeline
Voss Capital, LP125,000$7.3M0.42%013F-HR/ATimeline
BARCLAYS PLCin group BARCLAYS PLC115,562$6.75M<0.01%+26,54813F-HR/ATimelineGroup
MARSHALL WACE, LLPin group MARSHALL WACE, LLP108,210$6.32M0.01%-114,76913F-HRTimelineGroup
Quinn Opportunity Partners LLC107,600$6.28M0.46%new13F-HRTimeline
VOYA INVESTMENT MANAGEMENT LLCin group VOYA INVESTMENT MANAGEMENT LLC102,124$5.96M0.01%+34,86413F-HRTimelineGroup
TD Asset Management Inc95,144$5.55M<0.01%new13F-HRTimeline
Jefferies Financial Group Inc.in group Jefferies Financial Group Inc.90,542$5.28M0.05%-2,005,38913F-HRTimelineGroup
Atika Capital Management LLCin group Atika Capital Management LLC90,000$5.25M0.45%new13F-HRTimelineGroup
SANDERS MORRIS HARRIS LLC87,054$5.08M0.67%new13F-HRTimeline
Marex Group Ltdin group Marex Group Ltd86,859$5.07M0.06%new13F-HRTimelineGroup
Rafferty Asset Management, LLC82,856$4.84M0.02%+14,04913F-HRTimeline
Birchview Capital, LP78,728$4.6M3.47%-19,96913F-HRTimeline
Swiss National Bank76,300$4.45M<0.01%-1,20013F-HRTimeline
Patient Square Capital LP75,000$4.38M1.17%new13F-HRTimeline
SIMPLEX TRADING, LLC67,995$3.97M0.09%+3,73613F-HRTimeline
SEI INVESTMENTS COin group SEI INVESTMENTS CO67,273$3.93M<0.01%new13F-HRTimelineGroup
Apis Capital Advisors, LLC63,800$3.72M0.82%new13F-HRTimeline
Cubist Systematic Strategies, LLC62,365$3.64M0.05%new13F-HRTimeline
Ikarian Capital, LLCin group Ikarian Capital, LLC58,610$3.42M0.69%-61,37613F-HRTimelineGroup
STIFEL FINANCIAL CORPin group STIFEL FINANCIAL CORP58,276$3.4M<0.01%-8,70513F-HRTimelineGroup
Verition Fund Management LLC57,968$3.38M0.02%-34,62313F-HRTimeline
Headlands Technologies LLC57,408$3.35M0.27%+14,96413F-HRTimeline
Longaeva Partners L.P.55,000$3.21M0.68%new13F-HRTimeline
Hennion & Walsh Asset Management, Inc.51,613$3.01M0.11%+21,24413F-HRTimeline
Owl Creek Asset Management, L.P.49,389$2.88M0.33%new13F-HRTimeline
MANUFACTURERS LIFE INSURANCE COMPANY, T…in group MANUFACTURERS LIFE INSURANCE …48,762$2.85M<0.01%new13F-HRTimelineGroup
CI INVESTMENTS INC.in group CI INVESTMENTS INC.47,436$2.77M0.01%new13F-HRTimelineGroup
Atom Investors LP47,291$2.76M0.21%new13F-HRTimeline
PFM Health Sciences, LP46,353$2.71M0.23%-127,97813F-HRTimeline
LPL Financial LLC46,114$2.69M<0.01%new13F-HRTimeline
WINTON GROUP Ltdin group WINTON GROUP Ltd40,976$2.39M0.09%new13F-HRTimelineGroup
Alyeska Investment Group, L.P.in group Alyeska Investment Group, L.P.40,000$2.33M0.01%new13F-HRTimelineGroup
Monashee Investment Management LLC40,000$2.33M1.16%new13F-HRTimeline
Monaco Asset Management SAM39,913$2.33M0.87%-30,08713F-HRTimeline
Mirae Asset Global Investments Co., Ltd.group of 2 filers holding39,410$2.3M+82Timeline
BOOTHBAY FUND MANAGEMENT, LLC39,403$2.3M0.06%+5,79113F-HRTimeline
Legal & General Group Plcin group Legal & General Group Plc35,621$2.08M<0.01%013F-HRTimelineGroup
Militia Capital Partners, LPin group Militia Capital Management LLC35,000$2.04M0.95%+12,80013F-HR/ATimelineGroup
Shay Capital LLC34,997$2.04M0.37%-64,38613F-HRTimeline
GILDER GAGNON HOWE & CO LLC34,084$1.99M0.02%new13F-HRTimeline
Diamond Hill Capital Management, LLC (I…33,333$1.95M0.01%-49,32013F-HRTimeline
SUPERSTRING CAPITAL MANAGEMENT LP33,175$1.94M1.91%new13F-HRTimeline
D. E. Shaw & Co., Inc.in group D. E. Shaw & Co., Inc.32,537$1.9M<0.01%+5,00613F-HRTimelineGroup
Velan Capital Investment Management LP32,000$1.87M1.75%new13F-HRTimeline
CALIFORNIA STATE TEACHERS RETIREMENT SY…31,311$1.83M<0.01%-7,39613F-HRTimeline
SECTORAL ASSET MANAGEMENT INC30,740$1.79M1.11%-24,71013F-HRTimeline
Invesco Ltd.in group Invesco Ltd.30,264$1.77M<0.01%-136,53513F-HRTimelineGroup
Scientech Research LLC29,295$1.71M0.6%new13F-HRTimeline
TUDOR INVESTMENT CORP ET AL28,717$1.68M0.01%new13F-HR/ATimeline
Virtu Financial LLCin group Virtu Financial LLC28,201$1.65M0.09%+8,35113F-HRTimelineGroup
SPHERA FUNDS MANAGEMENT LTD.in group SPHERA FUNDS MANAGEMENT LTD.24,900$1.45M0.34%new13F-HRTimelineGroup
ALGERT GLOBAL LLC22,810$1.33M0.02%+3,47013F-HR/ATimeline
Y-Intercept (Hong Kong) Ltd22,704$1.33M0.03%-39,83413F-HRTimeline
Aristides Capital LLC22,500$1.31M0.39%new13F-HRTimeline
Bank of New York Mellon Corpin group Bank of New York Mellon Corp22,211$1.3M<0.01%-326,11713F-HRTimelineGroup
Exome Asset Management LLC22,090$1.29M0.85%new13F-HRTimeline
Palumbo Wealth Management LLC21,778$1.27M0.41%new13F-HRTimeline
WOLVERINE TRADING, LLC20,098$1.19M0.02%+6,30713F-HRTimeline
PERCEPTIVE ADVISORS LLCin group PERCEPTIVE ADVISORS LLC20,000$1.17M0.03%new13F-HRTimelineGroup
Resolute Capital Asset Partners LLC20,000$1.17M0.61%new13F-HRTimeline
Burkehill Global Management, LP20,000$1.17M0.07%new13F-HRTimeline
Massar Capital Management, LP20,000$1.17M0.42%-20,00013F-HRTimeline
Zurcher Kantonalbank (Zurich Cantonalba…19,897$1.16M<0.01%+9313F-HRTimeline
JANUS HENDERSON GROUP PLCin group Janus Henderson19,900$1.16M<0.01%+3,00013F-HRTimelineGroup
Polymer Capital Management (US) LLC17,835$1.04M0.14%new13F-HRTimeline
PROFUND ADVISORS LLC17,084$997K0.03%+3,36813F-HRTimeline
Sassicaia Capital Advisers LLC16,000$934K0.42%new13F-HRTimeline
Mitsubishi UFJ Asset Management Co., Lt…in group Mitsubishi UFJ Trust & Bankin…15,450$902K<0.01%+3013F-HRTimelineGroup
Aquatic Capital Management LLC15,125$883K0.02%-20,13713F-HRTimeline
RAYMOND JAMES FINANCIAL INCin group RAYMOND JAMES FINANCIAL INC14,698$858K<0.01%-25,59113F-HRTimelineGroup
PRELUDE CAPITAL MANAGEMENT, LLC12,160$710K0.06%new13F-HRTimeline
DNB Asset Management ASin group DNB Asset Management AS11,802$689K<0.01%-13,35713F-HRTimelineGroup
CITIGROUP INCin group CITIGROUP INC11,575$676K<0.01%-8,90713F-HRTimelineGroup
ENVESTNET ASSET MANAGEMENT INCin group ENVESTNET ASSET MANAGEMENT INC11,549$674K<0.01%new13F-HRTimelineGroup
WELLS FARGO & COMPANY/MNin group WELLS FARGO & COMPANY/MN10,843$633K<0.01%-9913F-HRTimelineGroup
SG Americas Securities, LLC10,579$617K<0.01%-84,18013F-HRTimeline
Corient Private Wealth LPin group Corient Private Wealth LP10,562$617K<0.01%-6813F-HRTimelineGroup
ARIZONA STATE RETIREMENT SYSTEM10,514$614K<0.01%-1,31013F-HRTimeline
China Universal Asset Management Co., L…9,617$561K0.05%-1,37913F-HRTimeline
Mraz, Amerine & Associates, Inc.9,319$544K0.08%new13F-HRTimeline
TEACHER RETIREMENT SYSTEM OF TEXAS8,646$505K<0.01%-2,16213F-HRTimeline
KLP KAPITALFORVALTNING AS8,400$490K<0.01%013F-HRTimeline
SIG BROKERAGE, LP7,831$457K0.12%new13F-HRTimeline
Campbell & CO Investment Adviser LLC7,771$454K0.03%new13F-HRTimeline
Total Clarity Wealth Management, Inc.7,608$444K0.12%-4,84213F-HRTimeline
Virtus Investment Advisers, LLCin group Virtus Investment Advisers, L…7,116$415K0.12%+1,23513F-HRTimelineGroup
Clear Harbor Asset Management, LLC7,000$409K0.03%-5,25013F-HR/ATimeline
NEOS Investment Management LLC6,250$365K<0.01%new13F-HRTimeline
Tema ETFs LLC6,250$365K0.03%new13F-HRTimeline
SCS Capital Management LLC6,164$360K<0.01%new13F-HRTimeline
Pictet Asset Management Holding SAin group Pictet Asset Management Holdi…5,900$344K<0.01%new13F-HRTimelineGroup
SummitTX Capital, L.P.5,698$333K0.01%-71,79713F-HRTimeline
Lido Advisors, LLCin group Lido Advisors, LLC5,544$324K<0.01%new13F-HRTimelineGroup
Diametric Capital, LP5,383$314K0.12%new13F-HRTimeline
Ballentine Partners, LLC5,153$301K<0.01%new13F-HRTimeline
Activest Wealth Management5,000$292K0.06%013F-HRTimeline
Financial Engines Advisors L.L.C.4,767$278K<0.01%new13F-HRTimeline
Bellevue Group AGin group Bellevue Group AG4,763$278K0.01%-14,84713F-HRTimelineGroup
Creative Planningin group Creative Planning4,735$276K<0.01%new13F-HRTimelineGroup
Sigma Planning Corp4,500$263K0.01%new13F-HRTimeline
Hudson Bay Capital Management LPin group Hudson Bay Capital Management…4,318$252K<0.01%-143,86413F-HR/ATimelineGroup
Requisite Capital Management, LLC4,092$239K0.04%new13F-HRTimeline
Coppell Advisory Solutions LLC4,000$238K0.03%new13F-HRTimeline
IQ EQ FUND MANAGEMENT (SINGAPORE) PRIVA…3,900$228K0.31%new13F-HRTimeline
COMMONWEALTH EQUITY SERVICES, LLC3,880$226K<0.01%new13F-HRTimeline
WESTFIELD CAPITAL MANAGEMENT CO LP3,828$223K<0.01%new13F-HRTimeline
Jump Financial, LLCin group Jump Financial, LLC3,826$223K<0.01%new13F-HR/ATimelineGroup
STATE OF WISCONSIN INVESTMENT BOARD3,568$208K<0.01%new13F-HRTimeline
Ensign Peak Advisors, Inc3,000$175K<0.01%new13F-HR/ATimeline
DEUTSCHE BANK AG\in group DEUTSCHE BANK AG\2,330$136K<0.01%new13F-HRTimelineGroup
Knott David M Jr2,000$117K0.05%new13F-HRTimeline
FNY Investment Advisers, LLC1,654$96K0.03%+71813F-HRTimeline
Point72 Europe (London) LLP1,552$90.6K<0.01%new13F-HRTimeline
GF FUND MANAGEMENT CO. LTD.1,180$68.9K<0.01%-6813F-HRTimeline
SBI Securities Co., Ltd.1,138$66.4K<0.01%-59213F-HRTimeline
Tower Research Capital LLC (TRC)in group Tower Research Capital LLC (T…1,042$60.8K<0.01%-6,04313F-HRTimelineGroup
Rockefeller Capital Management L.P.in group Rockefeller Capital Managemen…1,000$58.4K<0.01%new13F-HRTimelineGroup
T. Rowe Price Investment Management, In…977$58K<0.01%new13F-HRTimeline
CIBC Private Wealth Group LLCin group CIBC Bancorp USA Inc.850$49.6K<0.01%new13F-HRTimelineGroup
US BANCORP \DE\in group US BANCORP \DE\705$41.2K<0.01%-3213F-HRTimelineGroup
JONES FINANCIAL COMPANIES LLLPin group JONES FINANCIAL COMPANIES LLLP609$33.1K<0.01%+50913F-HRTimelineGroup
PRIVATE TRUST CO NA485$28.3K<0.01%new13F-HRTimeline
COMERICA BANK407$23.7K<0.01%+16313F-HRTimeline
FIRST HORIZON CORP386$22.5K<0.01%13F-HRTimeline
SALEM INVESTMENT COUNSELORS INC300$17.5K<0.01%013F-HRTimeline
Global Retirement Partners, LLC300$17.5K<0.01%new13F-HRTimeline
Steward Partners Investment Advisory, L…250$14.6K<0.01%new13F-HRTimeline
SIGNATUREFD, LLC249$14.5K<0.01%013F-HRTimeline
CWM, LLCin group CWM, LLC247$14K<0.01%+1313F-HRTimelineGroup
UMB Bank, n.a.200$11.7K<0.01%new13F-HRTimelineThe filing omitted confidential holdings, a later amendment may add them.
WPG Advisers, LLC196$11.4K0.01%new13F-HRTimeline
QUADRANT CAPITAL GROUP LLC187$10.9K<0.01%new13F-HRTimeline
Allworth Financial LP174$10.2K<0.01%+1013F-HRTimeline
TOTH FINANCIAL ADVISORY CORP165$9.63K<0.01%013F-HRTimeline
Versant Capital Management, Inc165$9.63K<0.01%-8413F-HRTimeline
Daiwa Securities Group Inc.in group Daiwa Securities Group Inc.158$9K<0.01%013F-HRTimelineGroup