13F-HR filed by Affinity Asset Advisors, LLC
Affinity Asset Advisors, LLC filed this 13F-HR for the quarter ended 2025-09-30, filed 2025-11-13, with 96 holding rows worth $1,147,980,949.
- Accession
- 0001999371-25-017685
- Filer
- CIK 1773195
- Filed
- 2025-11-13
- Accepted by EDGAR
- acceptance time not in the bulk data set
- Ingested
- Source
- SEC quarterly data set
13F report for Q3 2025
A holdings report, 96 entries on the cover page, a total value of $1,147,980,949 stated on the cover page (in dollars after the unit check, H1), rows summing to $1,147,980,949 with VALUE read as dollars as filed, 13F file number 028-20754. The quarter's positions are built on this report. The resolved quarter.
The information table after summing rows of one CUSIP and put or call (H4), with the CUSIP and issuer name as filed. Values in dollars after the unit check (method).
| Issuer as filed | CUSIP | Class | Amount | Value | Value read as | Type |
|---|---|---|---|---|---|---|
| VERONA PHARMA PLC | 925050106 | SPONSORED ADS | 625,000 | $66,693,750 | dollars as filed | |
| INSMED INC COM PAR $.01 | 457669307 | Stock | 450,000 | $64,804,500 | dollars as filed | |
| SPY | 78462F103 | SHS | 84,490 | $56,285,548 | dollars as filed | |
| XENON PHARMACEUTICALS INC COM | 98420N105 | Stock | 1,400,000 | $56,210,000 | dollars as filed | |
| MADRIGAL PHARMACEUTICALS INC COM | 558868105 | Stock | 115,000 | $52,745,900 | dollars as filed | |
| APOGEE THERAPEUTICS INC COM | 03770N101 | Stock | 1,173,426 | $46,620,215 | dollars as filed | |
| ARCELLX INC COMMON STOCK | 03940C100 | Stock | 500,000 | $41,050,000 | dollars as filed | |
| ALKERMES PLC | G01767105 | SHS | 1,250,000 | $37,500,000 | dollars as filed | |
| NUVALENT INC COM | 670703107 | Stock | 384,417 | $33,244,382 | dollars as filed | |
| ABIVAX SA- | 00370M103 | SPONSORED ADS | 360,000 | $30,564,000 | dollars as filed | |
| INSMED INC COM PAR $.01 | 457669307 | Stock | 205,000 | $29,522,050 | dollars as filed | call |
| MINERALYS THERAPEUTICS INC | 603170101 | COM | 750,000 | $28,440,000 | dollars as filed | |
| TEVA PHARMACEUTICAL INDS LTD SPONSORED ADS | 881624209 | ADR | 1,400,000 | $28,280,000 | dollars as filed | |
| MERUS N V | N5749R100 | COM | 285,769 | $26,905,151 | dollars as filed | |
| CENTESSA PHARMACEUTICALS PLC | 152309100 | SPONSORED ADS | 1,107,162 | $26,848,679 | dollars as filed | |
| LEXEO THERAPEUTICS INC | 52886X107 | COMMON STOCK | 3,870,527 | $25,700,299 | dollars as filed | |
| TREVI THERAPEUTICS INC COM | 89532M101 | Stock | 2,800,000 | $25,620,000 | dollars as filed | |
| SPYRE THERAPEUTICS INC | 00773J202 | COM NEW | 1,419,299 | $23,787,451 | dollars as filed | |
| REZOLUTE INC | 76200L309 | COMMON STOCK | 2,100,000 | $19,740,000 | dollars as filed | |
| CYTOKINETICS INC | 23282W605 | COM NEW | 350,000 | $19,236,000 | dollars as filed | |
| ORUKA THERAPEUTICS INC COM | 687604108 | Stock | 959,180 | $18,445,031 | dollars as filed | |
| UNIQURE NV | N90064101 | SHS | 300,000 | $17,511,000 | dollars as filed | |
| WAVE LIFE SCIENCES LTD SHS | Y95308105 | Stock | 2,100,000 | $15,372,000 | dollars as filed | |
| PROTAGONIST THERAPEUTICS | 74366E102 | COM | 220,600 | $14,654,458 | dollars as filed | |
| EXELIXIS INC COM | 30161Q104 | Stock | 350,000 | $14,455,000 | dollars as filed | put |
| SOLENO THERAPEUTICS INC | 834203309 | COM | 200,000 | $13,520,000 | dollars as filed | |
| AVALO THERAPEUTICS INC | 05338F306 | COMMON STOCK | 1,006,217 | $12,789,018 | dollars as filed | |
| ESTABLISHMENT LABS HOLDINGS | G31249108 | COMMON STOCK | 310,000 | $12,706,900 | dollars as filed | |
| KARYOPHARM THERAPEUTICS INC | 48576UAA4 | BOND | 15,250,000 | $12,456,200 | dollars as filed | principal |
| Ventyx Biosciences Inc | 92332V107 | Common Stock | 3,924,415 | $12,204,931 | dollars as filed | |
| ROIVANT SCIENCES LTD | G76279101 | SHS | 800,000 | $12,104,000 | dollars as filed | |
| TRAVERE THERAPEUTICS INC | 89422G107 | COM | 500,000 | $11,950,000 | dollars as filed | |
| DIANTHUS THERAPEUTICS INC | 252828108 | COM | 262,100 | $10,313,635 | dollars as filed | |
| TAYSHA GENE THERAPIES INC | 877619106 | COMMON STOCK | 3,000,000 | $9,810,000 | dollars as filed | |
| ERASCA INC COM | 29479A108 | Stock | 4,285,787 | $9,343,016 | dollars as filed | |
| NURIX THERAPEUTICS INC | 67080M103 | COMMON STOCK | 967,620 | $8,940,809 | dollars as filed | |
| VERA THERAPEUTICS INC | 92337R101 | COMMON STOCK | 303,330 | $8,814,770 | dollars as filed | |
| ENLIVEN THERAPEUTICS INC COM | 29337E102 | Stock | 400,000 | $8,188,000 | dollars as filed | |
| TRAVERE THERAPEUTICS INC | 89422GAA5 | CNV | 7,000,000 | $7,926,941 | dollars as filed | principal |
| NEWAMSTERDAM PHARMA CO NV | N62509109 | COMMON STOCK | 275,000 | $7,821,000 | dollars as filed | |
| CELLDEX THERAPEUTICS INC NEW | 15117B202 | COM NEW | 300,000 | $7,761,000 | dollars as filed | |
| PROQR THERAPEUTICS NV | N71542109 | SHS EURO | 3,600,000 | $7,668,000 | dollars as filed | |
| TARSUS PHARMACEUTICALS INC | 87650L103 | COMMON STOCK | 125,000 | $7,428,750 | dollars as filed | |
| SUMMIT THERAPEUTICS INC | 86627T108 | COM | 350,000 | $7,231,000 | dollars as filed | put |
| AKEBIA THERAPEUTICS INC | 00972D105 | COMMON STOCK | 2,450,000 | $6,688,500 | dollars as filed | |
| MONOPAR THERAPEUTICS INC | 61023L207 | COMMON STOCK | 79,483 | $6,491,377 | dollars as filed | |
| EXELIXIS INC COM | 30161Q104 | Stock | 150,000 | $6,195,000 | dollars as filed | call |
| ZURA BIO LTD | G9TY5A101 | COMMON STOCK | 1,274,351 | $5,517,940 | dollars as filed | |
| VIRIDIAN THERAPEUTICS INC | 92790C104 | COM | 250,000 | $5,395,000 | dollars as filed | |
| SAVARA INC | 805111101 | COM | 1,500,000 | $5,355,000 | dollars as filed | |
| INTELLIA THERAPEUTICS INC | 45826J105 | COM | 300,000 | $5,181,000 | dollars as filed | call |
| IMMUNOVANT INC | 45258J102 | COM | 300,000 | $4,836,000 | dollars as filed | |
| OMEROS CORP | 682143AK8 | NOTE 9.500% 6/1 | 5,525,000 | $4,713,378 | dollars as filed | principal |
| REVOLUTION MEDICINES INC COM | 76155X100 | Stock | 100,000 | $4,670,000 | dollars as filed | |
| OMEROS CORP | 682143102 | COM | 1,133,900 | $4,648,990 | dollars as filed | put |
| VAXCYTE INC COM | 92243G108 | Stock | 125,000 | $4,502,500 | dollars as filed | |
| NEWAMSTERDAM PHARMA CO NV-27 | N62509117 | WTS | 245,000 | $4,191,950 | dollars as filed | |
| CELCUITY INC | 15102KAA8 | NOTE 2.750% 8/0 | 3,000,000 | $3,998,273 | dollars as filed | principal |
| PERCEPTIVE CAPITAL SOLUTIONS | G70077105 | CL A ORD SHS | 350,000 | $3,755,500 | dollars as filed | |
| INSPIRE MED SYS INC COM | 457730109 | Stock | 50,000 | $3,710,000 | dollars as filed | |
| OVID THERAPEUTICS INC | 690469101 | COMMON STOCK | 2,650,000 | $3,445,000 | dollars as filed | |
| BRIDGEBIO PHARMA INC | 10806X102 | COM | 65,000 | $3,376,100 | dollars as filed | |
| JAZZ PHARMACEUTICALS PLC SHS USD | G50871105 | Stock | 25,000 | $3,295,000 | dollars as filed | |
| CRINETICS PHARMACEUTICALS INC COM | 22663K107 | Stock | 75,000 | $3,123,750 | dollars as filed | |
| MBX BIOSCIENCES INC COM | 55287L101 | Stock | 165,000 | $2,887,500 | dollars as filed | |
| AUTOLUS THERAPEUTICS PLC SPON | 05280R100 | COM | 1,750,000 | $2,852,500 | dollars as filed | |
| OCULAR THERAPEUTIX INC | 67576A100 | COM | 239,000 | $2,793,910 | dollars as filed | |
| OAKTREE ACQUISITION CORP III | G6717R120 | UNIT 10/04/2029 | 250,000 | $2,660,000 | dollars as filed | |
| CLIMB BIO INC | 28658R106 | COMMON STOCK | 1,300,000 | $2,613,000 | dollars as filed | |
| OLEMA PHARMACEUTICALS INC | 68062P106 | COM | 250,000 | $2,447,500 | dollars as filed | |
| OLEMA PHARMACEUTICALS INC | 68062P106 | COM | 250,000 | $2,447,500 | dollars as filed | call |
| SAGIMET BIOSCIENCES INC A | 786700104 | COMMON STOCK | 350,000 | $2,401,000 | dollars as filed | |
| ASTRIA THERAPEUTICS INC COM | 04635X102 | Stock | 300,000 | $2,184,000 | dollars as filed | |
| UNITED THERAPEUTICS CORP DEL COM | 91307C102 | Stock | 5,000 | $2,096,050 | dollars as filed | |
| GERON CORP | 374163103 | COM | 1,500,000 | $2,055,000 | dollars as filed | |
| ANTERIS TECHNOLOGIES GLOBAL | 03675P102 | COMMON STOCK | 450,000 | $2,025,000 | dollars as filed | |
| ORCHESTRA BIOMED HOLDINGS IN | 68572M106 | COMMON STOCK | 727,272 | $1,803,635 | dollars as filed | |
| EUPRAXIA PHARMACEUTICALS INC | 29842P105 | COM 298736 AL 3 EURONET WORLDWIDE INC NOTE 0.750% 3/1 | 300,000 | $1,770,000 | dollars as filed | |
| CULLINAN THERAPEUTICS INC | 230031106 | COM | 263,817 | $1,564,435 | dollars as filed | |
| ATYR PHARMA INC | 002120202 | COM NEW | 2,100,000 | $1,514,940 | dollars as filed | put |
| Milestone Pharmaceuticals Inc | 59935V107 | COM | 666,666 | $1,333,332 | dollars as filed | |
| COMPASS PATHWAYS PLC | 20451W101 | SPONSORED ADS | 200,000 | $1,146,000 | dollars as filed | |
| NEXTCURE INC | 65343E207 | COM NEW | 191,882 | $1,124,429 | dollars as filed | |
| KARYOPHARM THERAPEUTICS INC | 48576U205 | COMMON STOCK | 157,600 | $1,030,704 | dollars as filed | call |
| PERSPECTIVE THERAPEUTICS INC | 46489V302 | COMMON STOCK | 300,000 | $1,029,000 | dollars as filed | |
| Arbutus Biopharma Corp | 03879J100 | Common Shares, without par value | 211,500 | $960,210 | dollars as filed | call |
| SUTRO BIOPHARMA INC | 869367102 | COM | 752,722 | $653,664 | dollars as filed | |
| JADE BIOSCIENCES INC | 008064206 | COM NEW | 65,317 | $563,686 | dollars as filed | |
| ENGENE HOLDINGS INC | 29286M105 | COM | 77,000 | $525,910 | dollars as filed | |
| CONTEXT THERAPEUTICS INC | 21077P108 | COM | 402,653 | $390,090 | dollars as filed | |
| REPARE THERAPEUTICS INC | 760273102 | COM | 200,000 | $352,000 | dollars as filed | |
| CRESCENT BIOPHARMA INC | G2545C104 | COMMON STOCK | 17,998 | $213,996 | dollars as filed | |
| Adagio Med Hldgs Inc Com | 00534B100 | Common Stock | 80,000 | $155,200 | dollars as filed | |
| Q32 BIO INC | 746964105 | Common Stock | 27,777 | $54,998 | dollars as filed | |
| ARS PHARMACEUTICALS INC | 82835W108 | COM | 2,500 | $25,125 | dollars as filed | |
| Rocket Pharmaceuticals Inc W Exp 09/02/202 | 77313F114 | Warrant | 75,000 | $2,993 | dollars as filed |
Amendment chain
| Filing | Role | Filed | Accepted | Ingested |
|---|---|---|---|---|
| 13F-HR 0001999371-25-017685 | this filing | 2025-11-13 | acceptance time not in the bulk data set |