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Disclosery

EWTX EDGEWISE THERAPEUTICS INC

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COM (common), issuer CIK 1710072

201 managers (203 13F filers) reported a position in EWTX shares at 2024-12-31, 98,998,467 shares in all. 35 filers opened a position and 20 filers sold out during the quarter.

Managers
201
13F filers
203
New
35
Added
71
Reduced
63
Sold out
20
Shares held by filers
98,998,467

Shares held by filers adds up every 13F filer's report, so a share reported by a parent and by its subsidiary counts twice (H9). Managers counts each filer group once.

13D and 13G filers

No 13D or 13G on this security in the data. Structured 13D/G data starts 2024-12-18.

Insider trades

No Form 4 transaction on this security in the data.

13F holders, Q4 2024

Filers in the available 13F reports with a share position at 2024-12-31, filer groups collapsed to one row (method), largest first. Options and principal amounts are left out. A group row states no % of portfolio, since each member reports its own portfolio: the members' percents are listed under it. A value about 1,000 times or 1/1,000 of the price other filers imply is shown as filed but neither ranks the row nor enters a sum.

HolderSharesValue% of portfolioChangeSource
ORBIMED ADVISORS LLCin group ORBIMED ADVISORS LLC15,021,721$401M8.33%013F-HRTimelineGroup
RA CAPITAL MANAGEMENT, L.P.in group RA CAPITAL MANAGEMENT, L.P.8,909,091$238M3.17%013F-HRTimelineGroup
BlackRock, Inc.in group BlackRock, Inc.6,479,015$173M<0.01%+85,44813F-HRTimelineGroup
BAKER BROS. ADVISORS LPin group BAKER BROS. ADVISORS LP6,155,940$164M1.76%+315,88113F-HRTimelineGroup
NOVO HOLDINGS A/S5,000,000$134M8.08%-549,90013F-HRTimeline
JANUS HENDERSON GROUP PLCin group Janus Henderson4,983,940$133M0.07%+425,42113F-HRTimelineGroup
Paradigm Biocapital Advisors LPin group Paradigm Biocapital Advisors …4,493,929$120M4.17%+1,704,75713F-HRTimelineGroup
VANGUARD GROUP INCin group VANGUARD GROUP INC4,466,849$119M<0.01%-49,21413F-HRTimelineGroup
Cormorant Asset Management, LP3,406,534$91M5%013F-HRTimeline
PERCEPTIVE ADVISORS LLCin group PERCEPTIVE ADVISORS LLC2,685,537$71.7M2%+355,24313F-HRTimelineGroup
BRAIDWELL LP2,332,196$62.3M1.85%+373,88613F-HRTimeline
DEERFIELD MANAGEMENT COMPANY, L.P.in group DEERFIELD MANAGEMENT COMPANY,…2,078,509$55.5M1.06%+297,50313F-HRTimelineGroup
STATE STREET CORPin group STATE STREET CORP1,715,545$45.8M<0.01%+30,43013F-HRTimelineGroup
GEODE CAPITAL MANAGEMENT, LLCin group GEODE CAPITAL MANAGEMENT, LLC1,600,571$42.7M<0.01%+1,03613F-HRTimelineGroup
Driehaus Capital Management LLC1,493,791$39.9M0.33%-459,63313F-HRTimeline
Bellevue Group AGin group Bellevue Group AG1,428,929$38.2M0.73%013F-HRTimelineGroup
Frazier Life Sciences Management, L.P.1,271,245$33.9M1.41%-1,561,62213F-HRTimeline
VIKING GLOBAL INVESTORS LPin group VIKING GLOBAL INVESTORS LP1,224,986$32.7M0.11%-256,16013F-HRTimelineGroup
MPM BIOIMPACT LLC1,079,316$28.8M4.09%+162,15013F-HRTimeline
Artisan Partners Limited Partnership1,071,596$28.6M0.04%+70,96413F-HRTimeline
New Leaf Venture Partners, L.L.C.1,030,161$27.5M36.77%-523,50013F-HRTimeline
MILLENNIUM MANAGEMENT LLCin group MILLENNIUM MANAGEMENT LLC888,968$23.7M0.02%-98,06213F-HRTimelineGroup
First Light Asset Management, LLC780,639$20.8M1.99%new13F-HRTimeline
AMERICAN CENTURY COMPANIES INCin group AMERICAN CENTURY COMPANIES INC770,353$20.6M0.01%-164,03413F-HRTimelineGroup
Siren, L.L.C.in group Siren, L.L.C.734,343$19.6M0.87%+330,23013F-HRTimelineGroup
DIMENSIONAL FUND ADVISORS LPin group DIMENSIONAL FUND ADVISORS LP729,923$19.5M<0.01%+3,05213F-HRTimelineGroup
Deep Track Capital, LP710,421$19M0.71%-390,11513F-HRTimeline
D. E. Shaw & Co., Inc.in group D. E. Shaw & Co., Inc.686,371$18.3M0.02%+231,02313F-HRTimelineGroup
NORTHERN TRUST CORPin group NORTHERN TRUST CORP611,306$16.3M<0.01%+35,42613F-HRTimelineGroup
Foresite Capital Management VI LLCin group Foresite Capital Management V…585,000$15.6M6.96%13F-HRTimelineGroup
Woodline Partners LP567,218$15.1M0.1%+39,37913F-HRTimeline
Integral Health Asset Management, LLC550,000$14.7M1.3%new13F-HRTimeline
CHARLES SCHWAB INVESTMENT MANAGEMENT INCin group Charles Schwab Trust Co537,359$14.3M<0.01%+15,27313F-HRTimelineGroup
Opaleye Management Inc.480,000$12.8M2.24%-42,50013F-HRTimeline
CITADEL ADVISORS LLCin group CITADEL ADVISORS LLC469,451$12.5M0.01%-68,79813F-HRTimelineGroup
MORGAN STANLEYin group MORGAN STANLEY436,430$11.7M<0.01%+18,29913F-HR/ATimelineGroup
Nuveen Asset Management, LLCin group TIAA428,858$11.5M<0.01%+158,45213F-HRTimelineGroup
Sofinnova Investments, Inc.402,773$10.8M0.79%+18,00613F-HRTimeline
Logos Global Management LP400,000$10.7M1.25%-50,00013F-HRTimeline
Parkman Healthcare Partners LLC381,173$10.2M1.36%-275,89713F-HRTimeline
UBS Group AGgroup of 2 filers holding371,191$9.91M+211,592Timeline
Qube Research & Technologies Ltd369,442$9.86M0.02%+237,55013F-HRTimeline
GOLDMAN SACHS GROUP INCin group GOLDMAN SACHS GROUP INC346,891$9.26M<0.01%-135,33413F-HRTimelineGroup
Amundiin group Amundi341,687$8.69M<0.01%+191,26713F-HRTimelineGroup
Pictet Asset Management Holding SAin group Pictet Asset Management Holdi…301,241$8.04M0.01%new13F-HRTimelineGroup
Granahan Investment Management, LLC300,013$8.01M0.33%-211,89213F-HRTimeline
TANG CAPITAL MANAGEMENT LLCin group TANG CAPITAL MANAGEMENT LLC300,000$8.01M0.53%new13F-HRTimelineGroup
VOYA INVESTMENT MANAGEMENT LLCin group VOYA INVESTMENT MANAGEMENT LLC284,148$7.59M0.01%-23,69413F-HR/ATimelineGroup
DEUTSCHE BANK AG\in group DEUTSCHE BANK AG\275,837$7.36M<0.01%+57,95513F-HR/ATimelineGroup
Schonfeld Strategic Advisors LLC268,509$7.17M0.05%-277,03713F-HRTimeline
Candriam S.C.A.253,965$6.78M0.04%-40,65913F-HRTimeline
FMR LLCin group FMR LLC248,036$6.62M<0.01%-405,17213F-HRTimelineGroup
ADAGE CAPITAL PARTNERS GP, L.L.C.in group ADAGE CAPITAL PARTNERS GP, L.…240,000$6.41M0.01%+218,49113F-HRTimelineGroup
KENNEDY CAPITAL MANAGEMENT LLC236,642$6.32M0.14%+9,61913F-HRTimeline
Cubist Systematic Strategies, LLC219,549$5.86M0.1%new13F-HRTimeline
Bank of New York Mellon Corpin group Bank of New York Mellon Corp211,056$5.64M<0.01%+28413F-HRTimelineGroup
WELLINGTON MANAGEMENT GROUP LLPin group WELLINGTON MANAGEMENT GROUP L…202,893$5.42M<0.01%-2,42813F-HRTimelineGroup
Walleye Capital LLCin group Walleye Capital LLC198,662$5.3M0.05%-43,58913F-HRTimelineGroup
Moody Aldrich Partners LLC187,932$5.02M0.93%+36,77513F-HRTimeline
DAFNA Capital Management LLC187,140$5M1.27%-40,76613F-HRTimeline
Soleus Capital Management, L.P.183,300$4.89M0.37%new13F-HRTimeline
Aberdeen Group plcin group Aberdeen Group plc178,043$4.75M0.01%-78,60213F-HRTimelineGroup
BARCLAYS PLCin group BARCLAYS PLC133,657$3.57M<0.01%+14,30713F-HR/ATimelineGroup
STEMPOINT CAPITAL LP132,706$3.54M0.89%+112,80613F-HRTimeline
TWO SIGMA INVESTMENTS, LPgroup of 2 filers holding131,667$3.52M-175,191Timeline
JPMORGAN CHASE & COin group JPMORGAN CHASE & CO124,435$3.32M<0.01%-34,07113F-HRTimelineGroup
ALGERT GLOBAL LLC110,259$2.94M0.07%+100,85913F-HR/ATimeline
J. Goldman & Co LP107,278$2.86M0.1%+95,81213F-HRTimeline
Point72 Asset Management, L.P.in group Point72 Asset Management, L.P.106,562$2.85M0.01%new13F-HRTimelineGroup
RHUMBLINE ADVISERS102,397$2.73M<0.01%+1,52513F-HR/ATimeline
SCHRODER INVESTMENT MANAGEMENT GROUP93,061$2.52M<0.01%new13F-HRTimeline
Informed Momentum Co LLC91,333$2.44M0.35%-33,85113F-HRTimeline
Universal- Beteiligungs- und Serviceges…in group Universal- Beteiligungs- und …90,031$2.4M<0.01%13F-HRTimelineGroup
ACUTA CAPITAL PARTNERS, LLC87,658$2.34M2.35%+24,65813F-HRTimeline
Ally Bridge Group (NY) LLC83,176$2.22M1.9%-104,51913F-HRTimeline
HighVista Strategies LLC82,732$2.21M0.82%-6,10613F-HRTimeline
Exome Asset Management LLC81,473$2.18M1.64%+21,57313F-HRTimeline
Ensign Peak Advisors, Inc80,509$2.15M<0.01%new13F-HRTimeline
Harvest Investment Services, LLC79,381$2.12M0.52%new13F-HRTimeline
CITIGROUP INCin group CITIGROUP INC78,497$2.1M<0.01%+2,65613F-HRTimelineGroup
ALLIANCEBERNSTEIN L.P.77,260$2.06M<0.01%+1,30013F-HRTimeline
ALPS ADVISORS INCin group ALPS ADVISORS INC76,567$2.04M0.01%+7,66113F-HRTimelineGroup
Trexquant Investment LP74,781$2M0.02%new13F-HRTimeline
BRIDGER MANAGEMENT, LLC74,700$1.99M1.07%013F-HRTimeline
Swiss National Bank73,600$1.97M<0.01%013F-HRTimeline
Quantum Private Wealth, LLC73,524$1.96M0.63%+10013F-HRTimeline
NEW YORK STATE COMMON RETIREMENT FUND71,366$1.91M<0.01%+4,28413F-HR/ATimeline
Polar Asset Management Partners Inc.64,279$1.72M0.03%-93,30013F-HR/ATimeline
STATE OF WISCONSIN INVESTMENT BOARD61,521$1.64M<0.01%-10,26313F-HRTimeline
BAMCO INC /NY/in group Baron Capital60,000$1.6M<0.01%new13F-HRTimelineGroup
Jump Financial, LLCin group Jump Financial, LLC55,178$1.47M0.03%-76,62813F-HRTimelineGroup
SEI INVESTMENTS COin group SEI INVESTMENTS CO52,178$1.39M<0.01%-43213F-HRTimelineGroup
DekaBank Deutsche Girozentrale80,000$1.36M<0.01%013F-HRTimeline
Legal & General Group Plcin group Legal & General Group Plc50,292$1.34M<0.01%+6,63513F-HRTimelineGroup
SIMPLEX TRADING, LLC50,130$1.34M0.04%-23,90013F-HRTimeline
BANK OF AMERICA CORP /DE/in group BANK OF AMERICA CORP /DE/48,907$1.31M<0.01%-259,14413F-HRTimelineGroup
NORGES BANK47,755$1.28M<0.01%013F-HRTimeline
Verition Fund Management LLC46,391$1.24M0.01%new13F-HRTimeline
Mirae Asset Global Investments Co., Ltd.group of 2 filers holding44,468$1.19M+1,358Timeline
MetLife Investment Management, LLCin group MetLife Investment Management…44,612$1.19M0.01%+2,34113F-HRTimelineGroup
TUDOR INVESTMENT CORP ET AL43,809$1.17M0.01%+8,19613F-HRTimeline
Invesco Ltd.in group Invesco Ltd.43,435$1.16M<0.01%-21,34113F-HRTimelineGroup
EFG Asset Management (North America) Co…41,338$1.1M0.15%new13F-HRTimeline
MANUFACTURERS LIFE INSURANCE COMPANY, T…in group MANUFACTURERS LIFE INSURANCE …40,170$1.07M<0.01%+1,76013F-HRTimelineGroup
CALIFORNIA STATE TEACHERS RETIREMENT SY…37,638$1M<0.01%-28913F-HR/ATimeline
Corebridge Financial, Inc.in group Corebridge Financial, Inc.36,090$964K0.01%-2,72413F-HRTimelineGroup
INTECH INVESTMENT MANAGEMENT LLC34,844$930K0.01%+14,94413F-HRTimeline
WELLS FARGO & COMPANY/MNin group WELLS FARGO & COMPANY/MN33,918$906K<0.01%+11,56113F-HRTimelineGroup
PRELUDE CAPITAL MANAGEMENT, LLC33,164$885K0.07%+3,87113F-HRTimeline
BNP PARIBAS FINANCIAL MARKETSin group BNP PARIBAS FINANCIAL MARKETS33,082$883K<0.01%new13F-HRTimelineGroup
Russell Investments Group, Ltd.in group Russell Investments Group, Lt…33,079$883K<0.01%new13F-HRTimelineGroup
SUSQUEHANNA INTERNATIONAL GROUP, LLPin group SUSQUEHANNA INTERNATIONAL GRO…31,713$847K<0.01%-168,78713F-HRTimelineGroup
FRANKLIN RESOURCES INCin group Franklin Resources31,607$844K<0.01%-13,61613F-HRTimelineGroup
JANE STREET GROUP, LLCin group JANE STREET GROUP, LLC30,558$816K<0.01%-19,81213F-HRTimelineGroup
MARSHALL WACE, LLPin group MARSHALL WACE, LLP29,893$798K<0.01%-547,67213F-HRTimelineGroup
PRICE T ROWE ASSOCIATES INC /MD/29,050$776K<0.01%+5,24213F-HRTimeline
Squarepoint Ops LLCin group Squarepoint Ops LLC26,358$704K<0.01%+9,72913F-HRTimelineGroup
Brevan Howard Capital Management LPin group Brevan Howard Capital Managem…25,346$677K0.02%+14,09513F-HRTimelineGroup
ProShare Advisors LLC24,928$666K<0.01%+5,66913F-HRTimeline
Balyasny Asset Management L.P.in group Balyasny Asset Management23,364$624K<0.01%new13F-HRTimelineGroup
AMERIPRISE FINANCIAL INCin group AMERIPRISE FINANCIAL INC22,584$603K<0.01%new13F-HRTimelineGroup
GLENMEDE TRUST CO NAin group GLENMEDE TRUST CO NA21,919$585K<0.01%+3,83413F-HRTimelineGroup
Handelsbanken Fonder AB21,800$582K<0.01%new13F-HRTimeline
VICTORY CAPITAL MANAGEMENT INC21,568$576K<0.01%new13F-HRTimeline
READYSTATE ASSET MANAGEMENT LP21,362$570K0.02%new13F-HRTimeline
China Universal Asset Management Co., L…20,077$536K0.05%+2,04213F-HRTimeline
Graham Capital Management, L.P.18,415$492K0.02%+2,51613F-HRTimeline
Persistent Asset Partners Ltd16,593$465K0.4%13F-HRTimeline
HRT FINANCIAL LP17,113$456K<0.01%-79,29613F-HRTimeline
STATE BOARD OF ADMINISTRATION OF FLORID…16,870$450K<0.01%013F-HRTimeline
Police & Firemen's Retirement System of…15,453$413K<0.01%13F-HRTimeline
PROFUND ADVISORS LLC14,945$399K0.01%-30013F-HRTimeline
ENVESTNET ASSET MANAGEMENT INCin group ENVESTNET ASSET MANAGEMENT INC14,678$392K<0.01%+3,56113F-HRTimelineGroup
Cinctive Capital Management LP14,093$376K0.02%-32,15613F-HRTimeline
Nantahala Capital Management, LLCin group Nantahala Capital Management,…13,371$357K0.02%013F-HRTimelineGroup
Crestline Management, L.P.13,268$354K0.01%-13,71313F-HRTimeline
OPTIMIZE FINANCIAL INC.12,062$322K0.24%13F-HRTimeline
Orion Porfolio Solutions, LLC11,928$318K<0.01%-1,08313F-HRTimeline
Orion Portfolio Solutions, LLC11,928$318K<0.01%-1,08313F-HRTimeline
Rafferty Asset Management, LLC11,906$318K<0.01%-1,33813F-HRTimeline
GSA CAPITAL PARTNERS LLP11,593$310K0.02%new13F-HRTimeline
TEACHER RETIREMENT SYSTEM OF TEXAS11,143$298K<0.01%+1,77213F-HRTimeline
ARIZONA STATE RETIREMENT SYSTEM10,863$290K<0.01%+10513F-HRTimeline
HSBC HOLDINGS PLCin group HSBC HOLDINGS PLC10,759$283K<0.01%+2,03113F-HRTimelineGroup
AlphaCentric Advisors LLC10,316$275K0.27%new13F-HRTimeline
Bleakley Financial Group, LLC10,080$269K0.01%+18113F-HRTimeline
SFMG, LLC10,000$267K0.02%013F-HRTimeline
Neo Ivy Capital Management9,720$259K0.05%new13F-HRTimeline
AQR CAPITAL MANAGEMENT LLCin group AQR CAPITAL MANAGEMENT LLC9,366$250K<0.01%+42013F-HRTimelineGroup
BI Asset Management Fondsmaeglerselskab…in group BI Asset Management Fondsmaeg…8,853$236K<0.01%new13F-HRTimelineGroup
STRS OHIO8,200$219K<0.01%-1,20013F-HRTimeline
Zurcher Kantonalbank (Zurich Cantonalba…7,891$211K<0.01%-27013F-HRTimeline
Jain Global LLC7,850$210K0.01%13F-HRTimeline
Ameritas Investment Partners, Inc.in group Ameritas Investment Partners,…7,594$203K0.01%+48213F-HRTimelineGroup
Point72 (DIFC) Ltd6,889$184K0.02%new13F-HRTimeline
KLP KAPITALFORVALTNING AS6,800$182K<0.01%13F-HRTimeline
Quantbot Technologies LP3,855$103K<0.01%new13F-HRTimeline
Tower Research Capital LLC (TRC)in group Tower Research Capital LLC (T…3,676$98.1K<0.01%+3,36913F-HRTimelineGroup
ROYAL BANK OF CANADAin group ROYAL BANK OF CANADA3,324$89K<0.01%-5,59013F-HRTimelineGroup
US BANCORP \DE\in group US BANCORP \DE\3,309$88.3K<0.01%-5,22713F-HRTimelineGroup
MEEDER ASSET MANAGEMENT INCin group Meeder Advisory Services, Inc.3,307$88.3K0.01%013F-HRTimelineGroup
Aquatic Capital Management LLC2,894$77.3K<0.01%new13F-HRTimeline
PUBLIC EMPLOYEES RETIREMENT ASSOCIATION…2,849$76K<0.01%013F-HRTimeline
VIRTUS ADVISERS, LLCin group Virtus Investment Advisers, L…2,526$67.4K0.03%-2,61913F-HRTimelineGroup
AMALGAMATED BANK2,512$67K<0.01%013F-HRTimeline
AlphaQuest LLC2,203$58.8K0.01%-6,83213F-HRTimeline
Caitong International Asset Management …2,053$54.8K0.05%13F-HR/ATimeline
Quarry LP2,000$53.4K0.01%-1,50013F-HRTimeline
GF FUND MANAGEMENT CO. LTD.1,988$53.1K<0.01%13F-HRTimeline
DIADEMA PARTNERS LP1,359$36.3K0.04%13F-HRTimeline
GAMMA Investing LLC1,321$35.3K<0.01%+3313F-HRTimeline
OSAIC HOLDINGS, INC.in group OSAIC HOLDINGS, INC.1,064$28.4K<0.01%+16613F-HR/ATimelineGroup
NISA INVESTMENT ADVISORS, LLC1,049$28K<0.01%+6713F-HRTimeline
GROUP ONE TRADING LLC476$12.7K<0.01%new13F-HR/ATimeline
SIGNATUREFD, LLC466$12.4K<0.01%-7113F-HRTimeline
Daiwa Securities Group Inc.in group Daiwa Securities Group Inc.344$9K<0.01%013F-HRTimelineGroup
Lindbrook Capital, LLC325$8.68K<0.01%013F-HRTimeline
BFSG, LLC300$8.01K<0.01%-30013F-HRTimeline
SBI Securities Co., Ltd.243$6.49K<0.01%13F-HRTimeline
Aster Capital Management (DIFC) Ltd229$6.11K<0.01%new13F-HRTimeline
HighMark Wealth Management LLC165$4.41K<0.01%new13F-HRTimeline
Fortitude Family Office, LLC160$4.27K<0.01%013F-HRTimeline
Parallel Advisors, LLC136$3.63K<0.01%+313F-HRTimeline
COMERICA BANK108$2.88K<0.01%new13F-HR/ATimeline
FEDERATED HERMES, INC.in group FEDERATED HERMES, INC.107$2.86K<0.01%-213F-HRTimelineGroup
ROTHSCHILD INVESTMENT LLC90$2.4K<0.01%+2013F-HRTimeline
Sterling Capital Management LLC75$2K<0.01%013F-HRTimeline
Arax Advisory Partners75$2K<0.01%-2313F-HRTimeline
Versant Capital Management, Inc40$1.07K<0.01%013F-HRTimeline
CWM, LLCin group CWM, LLC26$1K<0.01%+613F-HRTimelineGroup
PRINCIPAL SECURITIES, INC.in group PRINCIPAL FINANCIAL GROUP INC27$721<0.01%013F-HRTimelineGroup
Smartleaf Asset Management LLC21$568<0.01%-5513F-HRTimeline
EverSource Wealth Advisors, LLCin group EverSource Wealth Advisors, L…18$480<0.01%new13F-HRTimelineGroup
NewEdge Advisors, LLC9$240<0.01%013F-HRTimeline
Farther Finance Advisors, LLC8$214<0.01%013F-HRTimeline
NATIONAL BANK OF CANADA /FI/in group NATIONAL BANK OF CANADA /FI/3$80<0.01%+213F-HRTimelineGroup
Global Retirement Partners, LLC3$80<0.01%-4413F-HRTimeline
IFP Advisors, Inc0$80<0.01%new13F-HRTimelineAmount filed as zero, left out of ratios.
Covestor Ltd5$00%-213F-HRTimelineValue filed as zero, left out of ratios.
CONCOURSE FINANCIAL GROUP SECURITIES, I…0$00%013F-HRTimelineValue filed as zero, left out of ratios. Amount filed as zero, left out of ratios.