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Disclosery

13F-HR filed by DAFNA Capital Management LLC

DAFNA Capital Management LLC filed this 13F-HR for the quarter ended 2024-12-31, filed 2025-02-14, with 82 holding rows worth $393,410,219.

Accession
0001389932-25-000004
Filer
CIK 1389933
Filed
2025-02-14
Accepted by EDGAR
acceptance time not in the bulk data set
Ingested
Source
SEC quarterly data set

Original filing

13F report for Q4 2024

A holdings report, 82 entries on the cover page, a total value of $393,410,219 stated on the cover page (in dollars after the unit check, H1), rows summing to $393,410,219 with VALUE read as dollars as filed, 13F file number 028-12327. The quarter's positions are built on this report. The resolved quarter.

Other managers

The information table after summing rows of one CUSIP and put or call (H4), with the CUSIP and issuer name as filed. Values in dollars after the unit check (method).

Issuer as filedCUSIPClassAmountValueValue read asType
SPDR SER TR78464A870S&P BIOTECH397,505$35,799,300dollars as filed
STEREOTAXIS INC85916J409COMMON STOCK13,680,554$31,191,663dollars as filed
REVOLUTION MEDICINES INC COM76155X100Stock631,176$27,607,638dollars as filed
ATRICURE INC04963C209COM641,673$19,609,527dollars as filed
MERUS N VN5749R100COM451,804$18,998,358dollars as filed
CYTOKINETICS INC23282W605COM NEW398,100$18,726,624dollars as filed
ASCENDIS PHARMA A/S DKK 1.0 AD04351P101SPONSORED ADR103,355$14,228,883dollars as filed
AXOGEN INC05463X106COM846,882$13,956,615dollars as filed
ISHARES TR464287556ISHARES BIOTECH102,500$13,551,525dollars as filed
BLUEPRINT MEDICINES CORP09627Y109COM149,763$13,062,329dollars as filed
IDEAYA BIOSCIENCES INC COM45166A102Stock498,827$12,819,854dollars as filed
XENON PHARMACEUTICALS INC COM98420N105Stock273,739$10,730,569dollars as filed
NEUROCRINE BIOSCIENCES INC64125C109COM71,615$9,775,448dollars as filed
Day One Biopharmaceuticals Inc23954D109Common Stock731,363$9,266,369dollars as filed
BIOHAVEN LTDG1110E107COM220,235$8,225,777dollars as filed
TANDEM DIABETES CARE INC875372203COM NEW223,208$8,039,952dollars as filed
SYNDAX PHARMACEUTICALS INC87164F105COM542,002$7,165,266dollars as filed
KALVISTA PHARMACEUTICALS INC483497103COM811,678$6,874,913dollars as filed
UROGEN PHARMA LTDM96088105COMMON STOCK492,515$5,245,285dollars as filed
DEXCOM INC COM252131107Stock65,552$5,097,979dollars as filed
BIOCRYST PHARMACEUTICALS INC COM09058V103Stock667,000$5,015,840dollars as filed
EDGEWISE THERAPEUTICS INC28036F105COM187,140$4,996,638dollars as filed
Ascendis Pharma A/S04351PAD3Convertible bond4,000,000$4,412,500dollars as filedprincipal
TELA BIO INC872381108COM1,441,029$4,351,908dollars as filed
PROQR THERAPEUTICS NVN71542109SHS EURO1,567,561$4,154,037dollars as filed
KURA ONCOLOGY INC COM50127T109Stock448,368$3,905,285dollars as filed
ARCUS BIOSCIENCES INC03969F109COM254,217$3,785,291dollars as filed
LAKEFRONT BIOTHERAPEUTICS NV36315X101SPON ADR130,175$3,579,813dollars as filed
ALKERMES PLCG01767105SHS120,700$3,471,332dollars as filed
INSULET CORP COM45784P101Stock12,400$3,237,268dollars as filed
ASTRIA THERAPEUTICS INC COM04635X102Stock299,775$2,679,989dollars as filed
IMMUNOVANT INC45258J102COM107,996$2,675,061dollars as filed
ALLOGENE THERAPEUTICS INC019770106COM1,240,118$2,641,451dollars as filed
VIKING THERAPEUTICS INC92686J106COM64,516$2,596,124dollars as filed
LEXEO THERAPEUTICS INC52886X107COMMON STOCK393,083$2,586,486dollars as filed
ACCURAY INC DEL004397105COM1,222,358$2,420,269dollars as filed
KEROS THERAPEUTICS INC COM492327101Stock130,316$2,062,902dollars as filed
INOGEN INC45780L104COM208,790$1,914,604dollars as filed
STOKE THERAPEUTICS INC86150R107COM171,097$1,887,200dollars as filed
BICARA THERAPEUTICS INC055477103COM105,500$1,837,810dollars as filed
BRAINSWAY LTD10501L106CMN193,208$1,821,951dollars as filed
MINERALYS THERAPEUTICS INC603170101COM146,500$1,803,415dollars as filed
IMMATICS N.VN44445109SHS245,000$1,741,950dollars as filed
ALECTOR INC014442107COMMON STOCK912,928$1,725,434dollars as filed
CENTURY THERAPEUTICS INC15673T100COM1,704,232$1,721,274dollars as filed
BICYCLE THERAPEUTICS PLC-ADR088786108SPONSORED ADS120,799$1,691,186dollars as filed
ITEOS THERAPEUTICS INC46565G104COM188,347$1,446,505dollars as filed
LARIMAR THERAPEUTICS INC517125100COM371,434$1,437,450dollars as filed
REGULUS THERAPEUTICS INC75915K309COM875,200$1,382,816dollars as filed
AUTOLUS THERAPEUTICS PLC SPON05280R100COM586,667$1,378,667dollars as filed
GOSSAMER BIO INC COM38341P102Stock1,409,262$1,274,818dollars as filed
2SEVENTY BIO INC COMMON STOCK901384107Stock429,252$1,262,001dollars as filed
LINEAGE CELL THERAPEUTICS IN53566P109COMMON STOCK2,511,374$1,261,965dollars as filed
NEUROGENE INC64135M105COMMON STOCK51,500$1,177,290dollars as filed
MEDIWOUND LTDM68830112COMMON STOCK64,479$1,147,726dollars as filed
ALIGN TECHNOLOGY INC COM016255101Stock5,500$1,146,805dollars as filed
BIONTECH SE SPONSORED ADS09075V102ADR8,500$968,575dollars as filed
STRUCTURE THERAPEUTICS INC COMP86366E106EQUITY35,500$962,760dollars as filed
ARS PHARMACEUTICALS INC82835W108COM88,790$936,735dollars as filed
COMPASS PATHWAYS PLC20451W101SPONSORED ADS243,210$919,334dollars as filed
TAYSHA GENE THERAPIES INC877619106COMMON STOCK522,500$903,925dollars as filed
POLYPID LTDM8001Q126COM291,273$885,470dollars as filed
FOGHORN THERAPEUTICS INC344174107COMMON STOCK186,717$881,304dollars as filed
PALVELLA THERAPEUTICS INC697947109COMMON STOCK71,452$857,424dollars as filed
SUTRO BIOPHARMA INC869367102COM437,079$804,225dollars as filed
CENTESSA PHARMACEUTICALS PLC152309100SPONSORED ADS47,453$794,838dollars as filed
VIR BIOTECHNOLOGY INC92764N102COM100,000$734,000dollars as filed
COMPUGEN LTDM25722105ORD447,202$684,219dollars as filed
ACRIVON THERAPEUTICS INC004890109CMN112,414$676,732dollars as filed
SAGE THERAPEUTICS INC78667J108COM108,200$587,526dollars as filed
ADICET BIO INC007002108COM600,000$577,200dollars as filed
MASIMO CORP COM574795100Stock3,000$495,900dollars as filed
AQUESTIVE THERAPEUTICS INC COM03843E104Stock127,000$452,120dollars as filed
APREA THERAPEUTICS INC03836J201COM NEW137,174$451,302dollars as filed
ADC THERAPEUTICS SAH0036K147COMMON STOCK224,081$445,921dollars as filed
PERSPECTIVE THERAPEUTICS INC46489V302COMMON STOCK130,169$415,239dollars as filed
BLACK DIAMOND THERAPEUTICS I09203E105COM140,000$299,600dollars as filed
BIOMX INC09090D301COM401,136$292,869dollars as filed
ACELYRIN INC00445A100COM87,989$276,285dollars as filed
COMPASS THERAPEUTICS INC20454B104COM158,394$229,671dollars as filed
NEVRO CORP64157F103COM38,000$141,360dollars as filed
SPERO THERAPEUTICS INC84833T103COM125,000$128,750dollars as filed

Amendment chain

FilingRoleFiledAcceptedIngested
13F-HR 0001389932-25-000004this filing2025-02-14acceptance time not in the bulk data set