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Disclosery

EWTX EDGEWISE THERAPEUTICS INC

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COM (common), issuer CIK 1710072

192 managers (195 13F filers) reported a position in EWTX shares at 2025-03-31, 105,337,701 shares in all. 31 filers opened a position and 38 filers sold out during the quarter.

Managers
192
13F filers
195
New
31
Added
68
Reduced
62
Sold out
38
Shares held by filers
105,337,701

Shares held by filers adds up every 13F filer's report, so a share reported by a parent and by its subsidiary counts twice (H9). Managers counts each filer group once.

13D and 13G filers

No 13D or 13G on this security in the data. Structured 13D/G data starts 2024-12-18.

Insider trades

No Form 4 transaction on this security in the data.

13F holders, Q1 2025

Filers in the available 13F reports with a share position at 2025-03-31, filer groups collapsed to one row (method), largest first. Options and principal amounts are left out. A group row states no % of portfolio, since each member reports its own portfolio: the members' percents are listed under it. A value about 1,000 times or 1/1,000 of the price other filers imply is shown as filed but neither ranks the row nor enters a sum.

HolderSharesValue% of portfolioChangeSource
ORBIMED ADVISORS LLCin group ORBIMED ADVISORS LLC15,021,721$330M7.94%013F-HRTimelineGroup
RA CAPITAL MANAGEMENT, L.P.in group RA CAPITAL MANAGEMENT, L.P.8,909,091$196M3.27%013F-HRTimelineGroup
PERCEPTIVE ADVISORS LLCin group PERCEPTIVE ADVISORS LLC6,547,328$144M5.11%+3,861,79113F-HR/ATimelineGroup
BlackRock, Inc.in group BlackRock, Inc.6,485,008$143M<0.01%+5,99313F-HRTimelineGroup
BAKER BROS. ADVISORS LPin group BAKER BROS. ADVISORS LP6,155,940$135M1.5%013F-HRTimelineGroup
JANUS HENDERSON GROUP PLCin group Janus Henderson5,282,154$123M0.07%+298,21413F-HRTimelineGroup
NOVO HOLDINGS A/S5,350,000$118M8.95%+350,00013F-HRTimeline
Paradigm Biocapital Advisors LPin group Paradigm Biocapital Advisors …4,394,556$96.7M4.45%-99,37313F-HRTimelineGroup
VANGUARD GROUP INCin group VANGUARD GROUP INC4,294,404$94.5M<0.01%-172,44513F-HRTimelineGroup
Cormorant Asset Management, LP4,101,992$90.2M6.83%+695,45813F-HRTimeline
BRAIDWELL LP2,458,808$54.1M1.9%+126,61213F-HRTimeline
DEERFIELD MANAGEMENT COMPANY, L.P.in group DEERFIELD MANAGEMENT COMPANY,…2,078,509$45.7M0.91%013F-HRTimelineGroup
First Light Asset Management, LLC1,852,290$40.8M4.65%+1,071,65113F-HRTimeline
STATE STREET CORPin group STATE STREET CORP1,717,724$37.8M<0.01%+2,17913F-HRTimelineGroup
Siren, L.L.C.in group Siren, L.L.C.1,696,444$37.3M2.11%+962,10113F-HR/ATimelineGroup
GEODE CAPITAL MANAGEMENT, LLCin group GEODE CAPITAL MANAGEMENT, LLC1,655,664$36.4M<0.01%+55,09313F-HRTimelineGroup
Bellevue Group AGin group Bellevue Group AG1,428,929$31.4M0.7%013F-HRTimelineGroup
Deep Track Capital, LP1,400,000$30.8M1%+689,57913F-HRTimeline
Driehaus Capital Management LLC1,375,742$30.3M0.29%-118,04913F-HRTimeline
MPM BIOIMPACT LLC1,105,444$24.3M4.18%+26,12813F-HRTimeline
Woodline Partners LP1,096,809$24.1M0.16%+529,59113F-HRTimeline
New Leaf Venture Partners, L.L.C.1,030,161$22.7M50.47%013F-HRTimeline
Artisan Partners Limited Partnership917,222$20.2M0.03%-154,37413F-HRTimeline
AMERICAN CENTURY COMPANIES INCin group AMERICAN CENTURY COMPANIES INC779,766$17.2M0.01%+9,41313F-HRTimelineGroup
BANK OF AMERICA CORP /DE/in group BANK OF AMERICA CORP /DE/695,426$15.3M<0.01%+646,51913F-HRTimelineGroup
Integral Health Asset Management, LLC675,000$14.8M1.65%+125,00013F-HRTimeline
DIMENSIONAL FUND ADVISORS LPin group DIMENSIONAL FUND ADVISORS LP667,499$14.7M<0.01%-62,42413F-HRTimelineGroup
MILLENNIUM MANAGEMENT LLCin group MILLENNIUM MANAGEMENT LLC615,118$13.5M0.01%-273,85013F-HRTimelineGroup
NORTHERN TRUST CORPin group NORTHERN TRUST CORP606,692$13.3M<0.01%-4,61413F-HRTimelineGroup
Foresite Capital Management VI LLCin group Foresite Capital Management V…585,000$12.9M7.05%013F-HRTimelineGroup
EVENTIDE ASSET MANAGEMENT, LLC568,310$12.5M0.25%new13F-HRTimeline
CHARLES SCHWAB INVESTMENT MANAGEMENT INCin group Charles Schwab Trust Co521,261$11.5M<0.01%-16,09813F-HR/ATimelineGroup
UBS Group AGgroup of 2 filers holding516,753$11.4M+145,562Timeline
VIKING GLOBAL INVESTORS LPin group VIKING GLOBAL INVESTORS LP490,035$10.8M0.03%-734,95113F-HRTimelineGroup
Parkman Healthcare Partners LLC425,407$9.36M1.11%+44,23413F-HRTimeline
MORGAN STANLEYin group MORGAN STANLEY408,997$9M<0.01%-27,43313F-HRTimelineGroup
Qube Research & Technologies Ltd397,573$8.75M0.01%+28,13113F-HRTimeline
Opaleye Management Inc.395,000$8.69M1.93%-85,00013F-HRTimeline
ADAGE CAPITAL PARTNERS GP, L.L.C.in group ADAGE CAPITAL PARTNERS GP, L.…390,000$8.58M0.02%+150,00013F-HRTimelineGroup
DEUTSCHE BANK AG\in group DEUTSCHE BANK AG\376,060$8.27M<0.01%+100,22313F-HRTimelineGroup
GOLDMAN SACHS GROUP INCin group GOLDMAN SACHS GROUP INC366,644$8.07M<0.01%+19,75313F-HR/ATimelineGroup
READYSTATE ASSET MANAGEMENT LP361,233$7.95M0.4%+339,87113F-HRTimeline
Sofinnova Investments, Inc.342,218$7.53M0.57%-60,55513F-HRTimeline
Aberdeen Group plcin group Aberdeen Group plc313,025$6.89M0.01%+134,98213F-HRTimelineGroup
Pictet Asset Management Holding SAin group Pictet Asset Management Holdi…302,513$6.66M0.01%+1,27213F-HRTimelineGroup
TANG CAPITAL MANAGEMENT LLCin group TANG CAPITAL MANAGEMENT LLC300,000$6.6M0.37%013F-HRTimelineGroup
PRICE T ROWE ASSOCIATES INC /MD/294,881$6.49M<0.01%+265,83113F-HRTimeline
VOYA INVESTMENT MANAGEMENT LLCin group VOYA INVESTMENT MANAGEMENT LLC280,735$6.18M0.01%-3,41313F-HR/ATimelineGroup
Ikarian Capital, LLCin group Ikarian Capital, LLC280,000$6.16M2.01%new13F-HRTimelineGroup
Schonfeld Strategic Advisors LLC278,973$6.14M0.04%+10,46413F-HRTimeline
Polar Capital Holdings Plcin group Polar Capital Holdings Plc250,000$5.5M0.03%new13F-HRTimelineGroup
Candriam S.C.A.225,796$4.97M0.03%-28,16913F-HRTimeline
KENNEDY CAPITAL MANAGEMENT LLC224,700$4.94M0.12%-11,94213F-HRTimeline
Granahan Investment Management, LLC217,667$4.79M0.24%-82,34613F-HRTimeline
Bank of New York Mellon Corpin group Bank of New York Mellon Corp210,735$4.64M<0.01%-32113F-HRTimelineGroup
Caption Management, LLC204,500$4.5M0.21%new13F-HRTimeline
Nuveen, LLCin group TIAA202,580$4.46M<0.01%13F-HRTimelineGroup
Amundiin group Amundi308,633$4.19M<0.01%-33,05413F-HRTimelineGroup
FMR LLCin group FMR LLC186,023$4.09M<0.01%-62,01313F-HRTimelineGroup
DAFNA Capital Management LLC183,140$4.03M1.14%-4,00013F-HRTimeline
Moody Aldrich Partners LLC182,095$4.01M0.84%-5,83713F-HRTimeline
STEMPOINT CAPITAL LP180,255$3.97M1.27%+47,54913F-HRTimeline
SUSQUEHANNA INTERNATIONAL GROUP, LLPin group SUSQUEHANNA INTERNATIONAL GRO…176,666$3.89M0.01%+144,95313F-HRTimelineGroup
D. E. Shaw & Co., Inc.in group D. E. Shaw & Co., Inc.140,548$3.09M<0.01%-545,82313F-HRTimelineGroup
JENNISON ASSOCIATES LLC128,746$2.83M<0.01%new13F-HRTimeline
Balyasny Asset Management L.P.in group Balyasny Asset Management120,910$2.66M0.01%+97,54613F-HRTimelineGroup
WELLINGTON MANAGEMENT GROUP LLPin group WELLINGTON MANAGEMENT GROUP L…113,303$2.49M<0.01%-89,59013F-HRTimelineGroup
RHUMBLINE ADVISERS108,837$2.39M<0.01%+6,44013F-HR/ATimeline
BARCLAYS PLCin group BARCLAYS PLC108,562$2.39M<0.01%-25,09513F-HR/ATimelineGroup
EFG Asset Management (North America) Co…104,386$2.3M0.38%+63,04813F-HRTimeline
Ally Bridge Group (NY) LLC102,650$2.26M2.04%+19,47413F-HRTimeline
NEUBERGER BERMAN GROUP LLCin group NEUBERGER BERMAN GROUP LLC102,181$2.25M<0.01%new13F-HRTimelineGroup
TWINBEECH CAPITAL LP100,826$2.22M0.04%new13F-HRTimeline
CITADEL ADVISORS LLCin group CITADEL ADVISORS LLC97,278$2.14M<0.01%-372,17313F-HRTimelineGroup
JPMORGAN CHASE & COin group JPMORGAN CHASE & CO91,368$2.01M<0.01%-33,06713F-HRTimelineGroup
HighVista Strategies LLC91,207$2.01M0.77%+8,47513F-HRTimeline
Quantum Private Wealth, LLC90,724$2M0.75%+17,20013F-HRTimeline
Universal- Beteiligungs- und Serviceges…in group Universal- Beteiligungs- und …89,425$1.97M<0.01%-60613F-HRTimelineGroup
ACUTA CAPITAL PARTNERS, LLC85,454$1.88M2.18%-2,20413F-HRTimeline
BOOTHBAY FUND MANAGEMENT, LLC85,214$1.87M0.07%new13F-HRTimeline
SCHRODER INVESTMENT MANAGEMENT GROUP79,151$1.84M<0.01%-13,91013F-HRTimeline
Swiss National Bank82,600$1.82M<0.01%+9,00013F-HRTimeline
ALLIANCEBERNSTEIN L.P.77,260$1.7M<0.01%013F-HRTimeline
BRIDGER MANAGEMENT, LLC74,700$1.64M0.82%013F-HRTimeline
CITIGROUP INCin group CITIGROUP INC74,307$1.63M<0.01%-4,19013F-HRTimelineGroup
Soleus Capital Management, L.P.72,300$1.59M0.12%-111,00013F-HRTimeline
NEW YORK STATE COMMON RETIREMENT FUND71,450$1.57M<0.01%+8413F-HR/ATimeline
Exome Asset Management LLC71,438$1.57M1.41%-10,03513F-HR/ATimeline
STATE OF WISCONSIN INVESTMENT BOARD71,132$1.56M<0.01%+9,61113F-HRTimeline
ALPS ADVISORS INCin group ALPS ADVISORS INC67,975$1.5M0.01%-8,59213F-HRTimelineGroup
DekaBank Deutsche Girozentrale80,000$1.44M<0.01%013F-HRTimeline
MANUFACTURERS LIFE INSURANCE COMPANY, T…in group MANUFACTURERS LIFE INSURANCE …56,988$1.25M<0.01%+16,81813F-HRTimelineGroup
Legal & General Group Plcin group Legal & General Group Plc50,348$1.11M<0.01%+5613F-HRTimelineGroup
PRELUDE CAPITAL MANAGEMENT, LLC49,995$1.1M0.11%+16,83113F-HRTimeline
Invesco Ltd.in group Invesco Ltd.48,130$1.06M<0.01%+4,69513F-HRTimelineGroup
NORGES BANK47,755$1.05M<0.01%013F-HR/ATimeline
Mirae Asset Global Investments Co., Ltd.group of 2 filers holding46,944$1.04M+2,476Timeline
TUDOR INVESTMENT CORP ET AL46,804$1.03M0.01%+2,99513F-HRTimeline
FRANKLIN RESOURCES INCin group Franklin Resources46,287$1.02M<0.01%+14,68013F-HRTimelineGroup
INTECH INVESTMENT MANAGEMENT LLC46,208$1.02M0.01%+11,36413F-HRTimeline
Squarepoint Ops LLCin group Squarepoint Ops LLC45,756$1.01M<0.01%+19,39813F-HR/ATimelineGroup
MetLife Investment Management, LLCin group MetLife Investment Management…43,883$965K0.01%-72913F-HRTimelineGroup
SEI INVESTMENTS COin group SEI INVESTMENTS CO42,962$945K<0.01%-9,21613F-HR/ATimelineGroup
OCONNOR, A Distinct Business Unit of UB…40,014$880K0.02%new13F-HRTimelineThe filing omitted confidential holdings, a later amendment may add them.
Skandinaviska Enskilda Banken AB (publ)37,591$827K<0.01%new13F-HRTimeline
Engineers Gate Manager LP36,358$800K0.01%new13F-HRTimeline
Corebridge Financial, Inc.in group Corebridge Financial, Inc.36,049$793K<0.01%-4113F-HRTimelineGroup
CALIFORNIA STATE TEACHERS RETIREMENT SY…36,028$793K<0.01%-1,61013F-HRTimeline
WELLS FARGO & COMPANY/MNin group WELLS FARGO & COMPANY/MN35,158$773K<0.01%+1,24013F-HRTimelineGroup
TWO SIGMA INVESTMENTS, LPin group TWO SIGMA INVESTMENTS, LP34,999$770K<0.01%-96,66813F-HRTimelineGroup
Verition Fund Management LLC34,719$764K<0.01%-11,67213F-HRTimeline
TD Asset Management Inc33,200$730K<0.01%new13F-HRTimeline
FRED ALGER MANAGEMENT, LLCin group FRED ALGER MANAGEMENT, LLC27,635$608K<0.01%new13F-HRTimelineGroup
Handelsbanken Fonder AB21,800$480K<0.01%013F-HRTimeline
GLENMEDE TRUST CO NAin group GLENMEDE TRUST CO NA21,809$480K<0.01%-11013F-HRTimelineGroup
ProShare Advisors LLC20,203$444K<0.01%-4,72513F-HRTimeline
ADAR1 Capital Management, LLCin group ADAR1 Capital Management, LLC20,000$440K0.08%new13F-HRTimelineGroup
China Universal Asset Management Co., L…18,993$418K0.04%-1,08413F-HRTimeline
Walleye Capital LLCgroup of 2 filers holding17,634$388K-181,028Timeline
Graham Capital Management, L.P.17,047$375K0.01%-1,36813F-HRTimeline
STATE BOARD OF ADMINISTRATION OF FLORID…16,870$371K<0.01%013F-HRTimeline
CIBC WORLD MARKETS CORP16,328$359K<0.01%new13F-HRTimeline
PROFUND ADVISORS LLC15,687$345K0.01%+74213F-HRTimeline
Police & Firemen's Retirement System of…15,453$340K<0.01%013F-HRTimeline
ENVESTNET ASSET MANAGEMENT INCin group ENVESTNET ASSET MANAGEMENT INC15,399$339K<0.01%+72113F-HRTimelineGroup
JANE STREET GROUP, LLCin group JANE STREET GROUP, LLC14,758$325K<0.01%-15,80013F-HR/ATimelineGroup
AMERIPRISE FINANCIAL INCin group AMERIPRISE FINANCIAL INC13,167$290K<0.01%-9,41713F-HRTimelineGroup
Creative Planningin group Creative Planning13,073$288K<0.01%new13F-HRTimelineGroup
SG Americas Securities, LLC12,883$283K<0.01%new13F-HRTimeline
GROUP ONE TRADING LLC12,631$278K0.01%+12,15513F-HRTimeline
Rafferty Asset Management, LLC12,217$269K<0.01%+31113F-HRTimeline
ARIZONA STATE RETIREMENT SYSTEM12,201$268K<0.01%+1,33813F-HRTimeline
Orion Porfolio Solutions, LLC11,633$256K<0.01%-29513F-HRTimeline
Orion Portfolio Solutions, LLC11,633$256K<0.01%-29513F-HR/ATimeline
TEACHER RETIREMENT SYSTEM OF TEXAS11,421$251K<0.01%+27813F-HRTimeline
CONTRAVISORY INVESTMENT MANAGEMENT, INC.10,209$225K0.05%new13F-HRTimeline
SFMG, LLC10,000$220K0.02%013F-HRTimeline
HSBC HOLDINGS PLCin group HSBC HOLDINGS PLC9,874$219K<0.01%-88513F-HRTimelineGroup
SummitTX Capital, L.P.9,664$213K0.01%13F-HRTimeline
AQR CAPITAL MANAGEMENT LLCin group AQR CAPITAL MANAGEMENT LLC9,419$207K<0.01%+5313F-HRTimelineGroup
AlphaQuest LLC9,358$206K0.02%+7,15513F-HRTimeline
Tidal Investments LLCin group Tidal Investments LLC9,220$203K<0.01%new13F-HRTimelineGroup
Tower Research Capital LLC (TRC)in group Tower Research Capital LLC (T…7,960$175K0.01%+4,28413F-HRTimelineGroup
Ameritas Investment Partners, Inc.in group Ameritas Investment Partners,…7,594$167K0.01%013F-HRTimelineGroup
Zurcher Kantonalbank (Zurich Cantonalba…7,073$156K<0.01%-81813F-HRTimeline
KLP KAPITALFORVALTNING AS6,800$150K<0.01%013F-HRTimeline
Virtus Investment Advisers, LLCgroup of 2 filers holding5,829$128K+3,303Timeline
ROYAL BANK OF CANADAin group ROYAL BANK OF CANADA5,729$126K<0.01%+2,40513F-HR/ATimelineGroup
BNP PARIBAS FINANCIAL MARKETSin group BNP PARIBAS FINANCIAL MARKETS5,504$121K<0.01%-27,57813F-HRTimelineGroup
STRS OHIO3,800$83.6K<0.01%-4,40013F-HRTimeline
US BANCORP \DE\in group US BANCORP \DE\3,213$70.7K<0.01%-9613F-HRTimelineGroup
Caitong International Asset Management …3,194$70.3K0.05%+1,14113F-HRTimeline
Allostery Investments LP3,000$66K0.1%new13F-HRTimeline
PUBLIC EMPLOYEES RETIREMENT ASSOCIATION…2,849$63K<0.01%013F-HRTimeline
AMALGAMATED BANK2,521$55K<0.01%+913F-HRTimeline
GF FUND MANAGEMENT CO. LTD.2,424$53.3K<0.01%+43613F-HRTimeline
GAMMA Investing LLC1,407$31K<0.01%+8613F-HR/ATimeline
Quarry LP1,200$26.4K0.01%-80013F-HRTimeline
BI Asset Management Fondsmaeglerselskab…in group BI Asset Management Fondsmaeg…1,163$26K<0.01%-7,69013F-HRTimelineGroup
NISA INVESTMENT ADVISORS, LLC1,056$23.2K<0.01%+713F-HRTimeline
CROWLEY WEALTH MANAGEMENT, INC.560$12.3K0.01%new13F-HRTimeline
SIGNATUREFD, LLC492$10.8K<0.01%+2613F-HRTimeline
Daiwa Securities Group Inc.in group Daiwa Securities Group Inc.344$8K<0.01%013F-HRTimelineGroup
MassMutual Private Wealth & Trust, FSB356$7.83K<0.01%new13F-HRTimeline
Lindbrook Capital, LLC285$6.27K<0.01%-4013F-HRTimeline
COLDSTREAM CAPITAL MANAGEMENT INC282$6.2K<0.01%new13F-HRTimeline
SBI Securities Co., Ltd.243$5.35K<0.01%013F-HRTimeline
SUMMIT SECURITIES GROUP LLC198$4.36K<0.01%new13F-HRTimeline
HighMark Wealth Management LLC165$3.63K<0.01%013F-HRTimeline
Fortitude Family Office, LLC160$3.52K<0.01%013F-HRTimeline
Parallel Advisors, LLC133$2.93K<0.01%-313F-HRTimeline
COMERICA BANK121$2.67K<0.01%+1313F-HRTimeline
OSAIC HOLDINGS, INC.in group OSAIC HOLDINGS, INC.121$2.66K<0.01%-94313F-HRTimelineGroup
ROTHSCHILD INVESTMENT LLC120$2.64K<0.01%+3013F-HRTimeline
BFSG, LLC100$2.2K<0.01%-20013F-HRTimeline
FEDERATED HERMES, INC.in group FEDERATED HERMES, INC.80$1.76K<0.01%-2713F-HRTimelineGroup
Sterling Capital Management LLC75$1.65K<0.01%013F-HRTimeline
TD PRIVATE CLIENT WEALTH LLC60$1.32K<0.01%new13F-HRTimeline
CWM, LLCin group CWM, LLC61$1K<0.01%+3513F-HRTimelineGroup
Parkside Financial Bank & Trust40$880<0.01%new13F-HRTimeline
Versant Capital Management, Inc40$880<0.01%013F-HRTimeline
JONES FINANCIAL COMPANIES LLLPin group JONES FINANCIAL COMPANIES LLLP32$745<0.01%new13F-HR/ATimelineGroup
PRINCIPAL SECURITIES, INC.in group PRINCIPAL FINANCIAL GROUP INC27$721<0.01%013F-HRTimelineGroup
CREATIVE FINANCIAL DESIGNS INC /ADV31$682<0.01%new13F-HRTimeline
Stephens Consulting, LLC30$660<0.01%new13F-HRTimeline
Smartleaf Asset Management LLC21$488<0.01%013F-HRTimeline
Russell Investments Group, Ltd.in group Russell Investments Group, Lt…19$418<0.01%-33,06013F-HRTimelineGroup
Farther Finance Advisors, LLC8$161<0.01%013F-HRTimeline
IFP Advisors, Inc0$66<0.01%013F-HRTimelineAmount filed as zero, left out of ratios.
Covestor Ltd5$00%013F-HRTimelineValue filed as zero, left out of ratios.
CONCOURSE FINANCIAL GROUP SECURITIES, I…0$0013F-HRTimelineValue filed as zero, left out of ratios. Amount filed as zero, left out of ratios.
NOMURA ASSET MANAGEMENT CO LTDin group NOMURA ASSET MANAGEMENT CO LTD0$00%013F-HRTimelineGroupValue filed as zero, left out of ratios. Amount filed as zero, left out of ratios.