13F-HR filed by PERCEPTIVE ADVISORS LLC
PERCEPTIVE ADVISORS LLC filed this 13F-HR for the quarter ended 2024-12-31, filed 2025-02-14, with 99 holding rows worth $3,628,669,681.
- Accession
- 0001012975-25-000090
- Filer
- CIK 1224962
- Filed
- 2025-02-14
- Accepted by EDGAR
- acceptance time not in the bulk data set
- Ingested
- Source
- SEC quarterly data set
13F report for Q4 2024
A holdings report, 99 entries on the cover page, a total value of $3,628,669,681 stated on the cover page (in dollars after the unit check, H1), rows summing to $3,628,669,681 with VALUE read as dollars as filed, 13F file number 028-10438. The quarter's positions are built on this report. The resolved quarter.
The information table after summing rows of one CUSIP and put or call (H4), with the CUSIP and issuer name as filed. Values in dollars after the unit check (method).
| Issuer as filed | CUSIP | Class | Amount | Value | Value read as | Type |
|---|---|---|---|---|---|---|
| VERONA PHARMA PLC | 925050106 | SPONSORED ADS | 6,392,106 | $296,849,403 | dollars as filed | |
| ARCELLX INC COMMON STOCK | 03940C100 | Stock | 3,478,888 | $266,795,921 | dollars as filed | |
| AMICUS THERAPEUTICS INC | 03152W109 | COM | 24,245,952 | $228,396,868 | dollars as filed | |
| RHYTHM PHARMACEUTICALS INC | 76243J105 | COM | 3,680,473 | $206,032,879 | dollars as filed | |
| NUVALENT INC COM | 670703107 | Stock | 2,619,977 | $205,091,800 | dollars as filed | |
| IOVANCE BIOTHERAPEUTICS INC | 462260100 | COM | 22,112,266 | $163,630,768 | dollars as filed | |
| VAXCYTE INC COM | 92243G108 | Stock | 1,718,417 | $140,669,616 | dollars as filed | |
| INTRA-CELLULAR THERAPIES INC | 46116X101 | COMMON STOCK | 1,288,328 | $107,601,155 | dollars as filed | |
| CENTESSA PHARMACEUTICALS PLC | 152309100 | SPONSORED ADS | 6,349,220 | $106,349,435 | dollars as filed | |
| PRAXIS PRECISION MEDICINES I | 74006W207 | COM NEW | 1,329,735 | $102,336,406 | dollars as filed | |
| ARTIVION INC | 228903100 | COM | 2,793,703 | $79,871,969 | dollars as filed | |
| MEIRAGTX HOLDINGS PLC | G59665102 | COMMON STOCK | 12,581,103 | $76,583,589 | dollars as filed | |
| EDGEWISE THERAPEUTICS INC | 28036F105 | COM | 2,685,537 | $71,703,838 | dollars as filed | |
| SOLENO THERAPEUTICS INC | 834203309 | COM | 1,501,040 | $67,471,748 | dollars as filed | |
| IMMATICS N.V | N44445109 | SHS | 9,383,456 | $66,716,372 | dollars as filed | |
| INSULET CORP COM | 45784P101 | Stock | 232,269 | $60,638,468 | dollars as filed | |
| SPYRE THERAPEUTICS INC | 00773J202 | COM NEW | 2,574,723 | $59,939,551 | dollars as filed | |
| ASTRIA THERAPEUTICS INC COM | 04635X102 | Stock | 6,485,420 | $57,979,654 | dollars as filed | |
| EVOLUS INC | 30052C107 | COM | 5,145,846 | $56,810,140 | dollars as filed | |
| AXSOME THERAPEUTICS INC. COM | 05464T104 | Stock | 664,074 | $56,187,301 | dollars as filed | |
| CARGO THERAPEUTICS INC COM | 14179K101 | Stock | 3,683,004 | $53,108,917 | dollars as filed | |
| IMMUNOVANT INC | 45258J102 | COM | 2,139,199 | $52,987,959 | dollars as filed | |
| PROTAGONIST THERAPEUTICS | 74366E102 | COM | 1,271,662 | $49,086,153 | dollars as filed | |
| APOGEE THERAPEUTICS INC COM | 03770N101 | Stock | 1,047,232 | $47,439,610 | dollars as filed | |
| ALDEYRA THERAPEUTICS INC | 01438T106 | COM | 9,275,851 | $46,286,496 | dollars as filed | |
| JANUX THERAPEUTICS INC | 47103J105 | COM | 817,895 | $43,790,098 | dollars as filed | |
| ARGENX SE SPONSORED ADR | 04016X101 | ADR | 67,471 | $41,494,665 | dollars as filed | |
| VIKING THERAPEUTICS INC | 92686J106 | COM | 995,894 | $40,074,775 | dollars as filed | |
| PRAXIS PRECISION MEDICINES I | 74006W207 | COM NEW | 500,000 | $38,480,000 | dollars as filed | call |
| AKERO THERAPEUTICS INC | 00973Y108 | COM | 1,185,592 | $32,983,169 | dollars as filed | |
| Intuitive Surgical,Inc. | 46120E602 | COM | 63,119 | $32,945,593 | dollars as filed | |
| ACRIVON THERAPEUTICS INC | 004890109 | CMN | 5,360,858 | $32,272,365 | dollars as filed | |
| ZYMEWORKS INC | 98985Y108 | COM | 2,130,020 | $31,183,493 | dollars as filed | |
| CELCUITY INC | 15102K100 | COM | 2,362,279 | $30,922,232 | dollars as filed | |
| VIRIDIAN THERAPEUTICS INC | 92790C104 | COM | 1,486,508 | $28,496,358 | dollars as filed | |
| SOLID BIOSCIENCES INC | 83422E204 | COMMON STOCK | 6,906,646 | $27,626,584 | dollars as filed | |
| AMYLYX PHARMACEUTICALS INC | 03237H101 | COM | 6,774,348 | $25,607,035 | dollars as filed | |
| PROCEPT BIOROBOTICS CORP COM | 74276L105 | Stock | 290,659 | $23,403,863 | dollars as filed | |
| NAUTILUS BIOTECHNOLOGY INC | 63909J108 | COM | 12,594,211 | $21,158,274 | dollars as filed | |
| CONTINEUM THERAPEUTICS INC CL A | 21217B100 | Stock | 1,441,249 | $21,114,298 | dollars as filed | |
| NATERA INC COM | 632307104 | Stock | 125,000 | $19,787,500 | dollars as filed | |
| INHIBIKASE THERAPEUTICS INC | 45719W205 | COMMON STOCK | 5,925,000 | $19,256,250 | dollars as filed | |
| ORCHESTRA BIOMED HOLDINGS IN | 68572M106 | COMMON STOCK | 4,592,556 | $18,370,224 | dollars as filed | |
| PENUMBRA INC COM | 70975L107 | Stock | 73,338 | $17,416,308 | dollars as filed | |
| SEPTERNA INC COM | 81734D104 | Stock | 750,000 | $17,175,000 | dollars as filed | |
| ORUKA THERAPEUTICS INC COM | 687604108 | Stock | 845,567 | $16,395,544 | dollars as filed | |
| INHIBRX BIOSCIENCES INC | 45720N103 | COM | 1,064,026 | $16,386,000 | dollars as filed | |
| ADMA BIOLOGICS INC | 000899104 | COM | 890,280 | $15,268,302 | dollars as filed | |
| BRIGHT MINDS BIOSCIENCES INC | 10919W405 | COMMON STOCK | 403,649 | $14,539,437 | dollars as filed | |
| ARVINAS INC | 04335A105 | COM | 740,749 | $14,200,158 | dollars as filed | |
| NEUROCRINE BIOSCIENCES INC | 64125C109 | COM | 100,050 | $13,656,825 | dollars as filed | |
| DYNE THERAPEUTICS INC COM | 26818M108 | Stock | 543,277 | $12,799,606 | dollars as filed | |
| XENON PHARMACEUTICALS INC COM | 98420N105 | Stock | 325,324 | $12,752,701 | dollars as filed | |
| MERUS N V | N5749R100 | COM | 300,000 | $12,615,000 | dollars as filed | |
| CG ONCOLOGY INC | 156944100 | COMMON STOCK | 419,450 | $12,029,826 | dollars as filed | |
| ANTERIS TECHNOLOGIES GLOBAL | 03675P102 | COMMON STOCK | 2,140,000 | $11,941,200 | dollars as filed | |
| EYEPOINT INC COM NEW | 30233G209 | Stock | 1,537,274 | $11,452,691 | dollars as filed | |
| EDWARDS LIFESCIENCES CORP COM | 28176E108 | Stock | 145,000 | $10,734,350 | dollars as filed | |
| TARSUS PHARMACEUTICALS INC | 87650L103 | COMMON STOCK | 186,662 | $10,335,475 | dollars as filed | |
| Adagio Med Hldgs Inc Com | 00534B100 | Common Stock | 9,812,419 | $10,303,039 | dollars as filed | |
| INSMED INC COM PAR $.01 | 457669307 | Stock | 144,000 | $9,941,760 | dollars as filed | |
| CRINETICS PHARMACEUTICALS INC COM | 22663K107 | Stock | 184,525 | $9,434,763 | dollars as filed | |
| RAPT THERAPEUTICS INC | 75382E109 | COM | 5,880,000 | $9,290,400 | dollars as filed | |
| OCULAR THERAPEUTIX INC | 67576A100 | COM | 1,078,495 | $9,210,347 | dollars as filed | |
| INARI MED INC | 45332Y109 | COM | 178,797 | $9,127,587 | dollars as filed | |
| ONKURE THERAPEUTICS INC | 68277Q105 | COM CL A | 1,004,439 | $8,638,175 | dollars as filed | |
| NURIX THERAPEUTICS INC | 67080M103 | COMMON STOCK | 330,614 | $6,228,768 | dollars as filed | |
| ZENAS BIOPHARMA INC COM | 98937L105 | Stock | 744,035 | $6,093,647 | dollars as filed | |
| IRHYTHM HOLDINGS INC COM | 450056106 | Stock | 65,153 | $5,874,846 | dollars as filed | |
| RAPPORT THERAPEUTICS INC COM | 75383L102 | Stock | 311,551 | $5,526,915 | dollars as filed | |
| HELIX ACQUISITION CORP II | G4444H101 | CL A ORD SHS | 500,000 | $5,250,000 | dollars as filed | |
| ROCKET PHARMACEUTICALS INC | 77313F106 | COM | 378,584 | $4,758,801 | dollars as filed | |
| CERIBELL INC | 15678C102 | COMMON STOCK | 180,546 | $4,672,530 | dollars as filed | |
| Veru Inc | 92536C103 | Common Stock | 6,483,157 | $4,217,294 | dollars as filed | |
| MEREO BIOPHARMA GROUP PLC | 589492107 | CMN | 1,085,512 | $3,799,292 | dollars as filed | |
| PERSPECTIVE THERAPEUTICS INC | 46489V302 | COMMON STOCK | 1,190,263 | $3,796,939 | dollars as filed | |
| LINEAGE CELL THERAPEUTICS IN | 53566P109 | COMMON STOCK | 7,236,843 | $3,636,514 | dollars as filed | |
| BIODESIX INC | 09075X108 | COM | 2,173,880 | $3,326,036 | dollars as filed | |
| ATHIRA PHARMA INC | 04746L104 | COM | 5,402,964 | $3,169,919 | dollars as filed | |
| PEPGEN INC COM | 713317105 | Stock | 829,536 | $3,143,941 | dollars as filed | |
| IMMUNITYBIO INC | 45256X103 | COM | 1,221,734 | $3,127,639 | dollars as filed | |
| BICYCLE THERAPEUTICS PLC-ADR | 088786108 | SPONSORED ADS | 197,108 | $2,759,512 | dollars as filed | |
| LYRA THERAPEUTICS INC | 55234L105 | COM | 12,757,562 | $2,628,057 | dollars as filed | |
| VERRICA PHARMACEUTICALS INC | 92511W108 | COM | 3,249,669 | $2,274,768 | dollars as filed | |
| FORTE BIOSCIENCES INC | 34962G208 | COMMON STOCK | 95,742 | $2,174,301 | dollars as filed | |
| SCPHARMACEUTICALS INC | 810648105 | COM | 500,000 | $1,770,000 | dollars as filed | |
| TRINITY BIOTECH INVT LTD | 896438504 | SPONS ADR NEW | 1,790,000 | $1,575,200 | dollars as filed | |
| TRAWS PHARMA INC | 68232V884 | COM NEW | 164,157 | $1,457,714 | dollars as filed | |
| FULCRUM THERAPEUTICS INC | 359616109 | COMMON STOCK | 238,000 | $1,118,600 | dollars as filed | |
| LEXEO THERAPEUTICS INC | 52886X107 | COMMON STOCK | 139,835 | $920,114 | dollars as filed | |
| NOVAVAX INC | 670002401 | COM NEW | 100,000 | $804,000 | dollars as filed | put |
| NANOBIOTIX | 63009J107 | SPONSORED ADS | 266,093 | $763,687 | dollars as filed | |
| Applied Therapeutics Inc | 03828A101 | Common Stock | 860,000 | $736,332 | dollars as filed | |
| ENSYSCE BIOSCIENCES INC | 293602504 | COM NEW | 86,666 | $705,461 | dollars as filed | |
| DELCATH SYSTEMS INC | 24661P807 | COMMON STOCK | 50,000 | $602,000 | dollars as filed | |
| PYXIS ONCOLOGY INC COMMON STOCK | 747324101 | Stock | 188,462 | $294,001 | dollars as filed | |
| APYX MEDICAL CORPORATION | 03837C106 | COM | 150,000 | $237,000 | dollars as filed | |
| REVOLUTION MEDICINES INC | 76155X118 | *W EXP 12/17/202 | 250,000 | $45,000 | dollars as filed | |
| SURROZEN INC | 86889P117 | *W EXP 08/01/203 | 166,666 | $3,567 | dollars as filed |
Amendment chain
| Filing | Role | Filed | Accepted | Ingested |
|---|---|---|---|---|
| 13F-HR 0001012975-25-000090 | this filing | 2025-02-14 | acceptance time not in the bulk data set |