13F-HR filed by TANG CAPITAL MANAGEMENT LLC
TANG CAPITAL MANAGEMENT LLC filed this 13F-HR for the quarter ended 2024-12-31, filed 2025-02-14, with 183 holding rows worth $1,511,333,226.
- Accession
- 0001214659-25-002812
- Filer
- CIK 1232621
- Filed
- 2025-02-14
- Accepted by EDGAR
- acceptance time not in the bulk data set
- Ingested
- Source
- SEC quarterly data set
13F report for Q4 2024
A holdings report, 183 entries on the cover page, a total value of $1,511,333,226 stated on the cover page (in dollars after the unit check, H1), rows summing to $1,511,333,226 with VALUE read as dollars as filed, 13F file number 028-14822. The quarter's positions are built on this report. The resolved quarter.
Other managers
- included managerTANG KEVIN028-14818
The information table after summing rows of one CUSIP and put or call (H4), with the CUSIP and issuer name as filed. Values in dollars after the unit check (method).
| Issuer as filed | CUSIP | Class | Amount | Value | Value read as | Type |
|---|---|---|---|---|---|---|
| TARSUS PHARMACEUTICALS INC | 87650L103 | COMMON STOCK | 2,254,797 | $124,848,110 | dollars as filed | |
| AURINIA PHARMACEUTICALS INC COM | 05156V102 | Stock | 8,429,500 | $75,696,910 | dollars as filed | |
| LAKEFRONT BIOTHERAPEUTICS NV | 36315X101 | SPON ADR | 2,161,200 | $59,433,000 | dollars as filed | |
| EVOLUS INC | 30052C107 | COM | 4,997,399 | $55,171,285 | dollars as filed | |
| MIRUM PHARMACEUTICALS INC | 604749101 | COM | 1,237,107 | $51,154,374 | dollars as filed | |
| VIRIDIAN THERAPEUTICS INC | 92790C104 | COM | 2,492,925 | $47,789,372 | dollars as filed | |
| IMMUNOCORE HLDGS PLC ADS | 45258D105 | ADR | 1,555,600 | $45,890,200 | dollars as filed | |
| KALVISTA PHARMACEUTICALS INC | 483497103 | COM | 4,893,847 | $41,450,884 | dollars as filed | |
| RELAY THERAPEUTICS INC COM | 75943R102 | Stock | 8,068,058 | $33,240,399 | dollars as filed | |
| REPLIMUNE GROUP INC | 76029N106 | COMMON STOCK | 2,700,000 | $32,697,000 | dollars as filed | |
| PTC THERAPEUTICS INC | 69366J200 | COM | 700,000 | $31,598,000 | dollars as filed | |
| BIONTECH SE SPONSORED ADS | 09075V102 | ADR | 270,000 | $30,766,500 | dollars as filed | |
| ACADIA PHARMACEUTICALS INC | 004225108 | COM | 1,500,000 | $27,525,000 | dollars as filed | |
| INTRA-CELLULAR THERAPIES INC | 46116X101 | COMMON STOCK | 300,000 | $25,056,000 | dollars as filed | |
| VAXCYTE INC COM | 92243G108 | Stock | 300,000 | $24,558,000 | dollars as filed | |
| DYNAVAX TECHNOLOGIES CORP | 268158201 | COM NEW | 1,850,000 | $23,624,500 | dollars as filed | |
| LENZ THERAPEUTICS INC | 52635N103 | COM | 766,940 | $22,141,558 | dollars as filed | |
| NEUROCRINE BIOSCIENCES INC | 64125C109 | COM | 150,000 | $20,475,000 | dollars as filed | |
| ALTIMMUNE INC | 02155H200 | COM NEW | 2,750,000 | $19,827,500 | dollars as filed | |
| NVIDIA Corp | 67066G104 | COM | 142,569 | $19,145,639 | dollars as filed | |
| ANAPTYSBIO INC | 032724106 | COM | 1,330,879 | $17,620,838 | dollars as filed | |
| ANI PHARMACEUTICALS INC | 00182C103 | COM | 317,500 | $17,551,400 | dollars as filed | |
| JAZZ PHARMACEUTICALS PLC SHS USD | G50871105 | Stock | 140,000 | $17,241,000 | dollars as filed | |
| ZYMEWORKS INC | 98985Y108 | COM | 1,100,000 | $16,104,000 | dollars as filed | |
| ATEA PHARMACEUTICALS INC | 04683R106 | COMMON STOCK | 4,788,912 | $16,042,855 | dollars as filed | |
| AVADEL PHARMACEUTICALS PLC | G29687103 | COM SHS | 1,497,500 | $15,738,725 | dollars as filed | |
| META PLATFORMS INC CL A | 30303M102 | COM | 26,600 | $15,574,453 | dollars as filed | |
| LEGEND BIOTECH CORP | 52490G102 | SPONSORED ADS | 450,000 | $14,643,000 | dollars as filed | |
| GSK PLC SPONSORED ADR | 37733W204 | ADR | 400,000 | $13,528,000 | dollars as filed | |
| SANOFI SA SPONSORED ADR | 80105N105 | ADR | 270,000 | $13,022,100 | dollars as filed | |
| LIQUIDIA CORPORATION COM NEW | 53635D202 | Stock | 1,100,000 | $12,936,000 | dollars as filed | |
| VIKING THERAPEUTICS INC | 92686J106 | COM | 320,000 | $12,876,800 | dollars as filed | |
| TELADOC HEALTH INC | 87918A105 | COM | 1,400,000 | $12,726,000 | dollars as filed | |
| MODERNA INC | 60770K107 | COM | 300,000 | $12,474,000 | dollars as filed | |
| KINIKSA PHARMACEUTICALS INTL P ORD SHS CL A | G52694109 | Stock | 628,609 | $12,433,886 | dollars as filed | |
| CYBIN INC | 23256X407 | COM NEW | 1,330,097 | $11,731,456 | dollars as filed | |
| VANDA PHARMACEUTICALS INC | 921659108 | COM | 2,353,307 | $11,272,341 | dollars as filed | |
| CULLINAN THERAPEUTICS INC | 230031106 | COM | 921,138 | $11,219,461 | dollars as filed | |
| CRISPR THERAPEUTICS AG NAMEN AKT | H17182108 | Stock | 266,500 | $10,489,440 | dollars as filed | |
| NUVATION BIO INC COM CL A | 67080N101 | Stock | 3,900,000 | $10,374,000 | dollars as filed | |
| HILLEVAX INC | 43157M102 | COM | 4,920,000 | $10,184,400 | dollars as filed | |
| ASTRAZENECA PLC SPONSORED ADR | 046353108 | ADR | 150,000 | $9,828,000 | dollars as filed | |
| ELANCO ANIMAL HEALTH INC COM | 28414H103 | Stock | 800,000 | $9,688,000 | dollars as filed | |
| HARMONY BIOSCIENCES HLDGS IN | 413197104 | COM | 281,200 | $9,676,092 | dollars as filed | |
| ADMA BIOLOGICS INC | 000899104 | COM | 550,000 | $9,432,500 | dollars as filed | |
| ROCKET PHARMACEUTICALS INC | 77313F106 | COM | 750,000 | $9,427,500 | dollars as filed | |
| CARGO THERAPEUTICS INC COM | 14179K101 | Stock | 640,000 | $9,228,800 | dollars as filed | |
| DESIGN THERAPEUTICS INC | 25056L103 | COM | 1,480,975 | $9,137,616 | dollars as filed | |
| COMPASS THERAPEUTICS INC | 20454B104 | COM | 5,900,000 | $8,555,000 | dollars as filed | |
| BAUSCH PLUS LOMB CORP | 071705107 | COMMON SHARES | 450,000 | $8,127,000 | dollars as filed | |
| EDGEWISE THERAPEUTICS INC | 28036F105 | COM | 300,000 | $8,010,000 | dollars as filed | |
| ADICET BIO INC | 007002108 | COM | 8,145,988 | $7,836,440 | dollars as filed | |
| ESSA PHARMA INC | 29668H708 | COM NEW | 4,300,000 | $7,697,000 | dollars as filed | |
| BIOAGE LABS INC COM | 09077V100 | Stock | 1,318,361 | $7,633,310 | dollars as filed | |
| ABCELLERA BIOLOGICS INC COM | 00288U106 | Stock | 2,582,816 | $7,567,651 | dollars as filed | |
| CYTOMX THERAPEUTICS INC | 23284F105 | COMMON STOCK | 7,311,760 | $7,531,113 | dollars as filed | |
| SINGULAR GENOMICS SYSTEMS IN | 82933R308 | COM | 372,000 | $7,227,960 | dollars as filed | |
| IMMUNITYBIO INC | 45256X103 | COM | 2,814,192 | $7,204,332 | dollars as filed | |
| INSMED INC COM PAR $.01 | 457669307 | Stock | 100,000 | $6,904,000 | dollars as filed | |
| BEONE MEDICINES LTD SPONSORED ADS | 07725L102 | ADR | 37,000 | $6,834,270 | dollars as filed | |
| Ventyx Biosciences Inc | 92332V107 | Common Stock | 3,100,000 | $6,789,000 | dollars as filed | |
| JOURNEY MED CORP | 48115J109 | COM | 1,725,569 | $6,746,975 | dollars as filed | |
| BIOCRYST PHARMACEUTICALS INC COM | 09058V103 | Stock | 800,000 | $6,016,000 | dollars as filed | |
| DIANTHUS THERAPEUTICS INC | 252828108 | COM | 264,692 | $5,770,286 | dollars as filed | |
| NKARTA INC | 65487U108 | COMMON STOCK | 2,293,719 | $5,711,360 | dollars as filed | |
| ALX ONCOLOGY HOLDINGS INC | 00166B105 | COMMON STOCK | 3,296,883 | $5,505,795 | dollars as filed | |
| BIOGEN INC COM | 09062X103 | Stock | 35,000 | $5,352,200 | dollars as filed | |
| IONIS PHARMACEUTICALS INC COM | 462222100 | Stock | 150,000 | $5,244,000 | dollars as filed | |
| BIOHAVEN LTD | G1110E107 | COM | 140,000 | $5,229,000 | dollars as filed | |
| SEER INC | 81578P106 | COM CL A | 2,194,423 | $5,069,117 | dollars as filed | |
| COHERUS ONCOLOGY INC | 19249H103 | COM | 3,650,000 | $5,037,000 | dollars as filed | |
| KEZAR LIFE SCIENCES INC | 49372L209 | COM NEW | 720,000 | $4,838,400 | dollars as filed | |
| NOVAVAX INC | 670002401 | COM NEW | 600,000 | $4,824,000 | dollars as filed | |
| ALUMIS INC | 022307102 | COM | 600,000 | $4,716,000 | dollars as filed | |
| CYTOKINETICS INC | 23282W605 | COM NEW | 100,000 | $4,704,000 | dollars as filed | |
| APOGEE THERAPEUTICS INC COM | 03770N101 | Stock | 100,000 | $4,530,000 | dollars as filed | |
| LANTHEUS HLDGS INC | 516544103 | COM | 50,000 | $4,473,000 | dollars as filed | |
| BLACK DIAMOND THERAPEUTICS I | 09203E105 | COM | 2,070,209 | $4,430,247 | dollars as filed | |
| REVOLUTION MEDICINES INC COM | 76155X100 | Stock | 100,000 | $4,374,000 | dollars as filed | |
| MERUS N V | N5749R100 | COM | 100,000 | $4,205,000 | dollars as filed | |
| PHATHOM PHARMACEUTICALS INC | 71722W107 | COMMON STOCK | 500,000 | $4,060,000 | dollars as filed | |
| NUVALENT INC COM | 670703107 | Stock | 50,000 | $3,914,000 | dollars as filed | |
| ALEXANDRIA REAL ESTATE EQ INC COM | 015271109 | REIT | 40,000 | $3,902,000 | dollars as filed | |
| COMPASS PATHWAYS PLC | 20451W101 | SPONSORED ADS | 1,000,000 | $3,780,000 | dollars as filed | |
| IOVANCE BIOTHERAPEUTICS INC | 462260100 | COM | 500,000 | $3,700,000 | dollars as filed | |
| TECTONIC THERAPEUTIC INC | 878972108 | COMMON STOCK | 79,166 | $3,655,093 | dollars as filed | |
| GRAIL INC | 384747101 | COM | 200,000 | $3,570,000 | dollars as filed | |
| STOKE THERAPEUTICS INC | 86150R107 | COM | 300,000 | $3,309,000 | dollars as filed | |
| HERON THERAPEUTICS INC | 427746102 | COM | 2,140,271 | $3,274,615 | dollars as filed | |
| C4 THERAPEUTICS INC | 12529R107 | COM STK | 900,000 | $3,240,000 | dollars as filed | |
| FATE THERAPEUTICS INC | 31189P102 | COM | 1,855,954 | $3,062,324 | dollars as filed | |
| TG THERAPEUTICS INC COM | 88322Q108 | Stock | 100,000 | $3,010,000 | dollars as filed | |
| CORBUS PHARMACEUTICALS | 21833P301 | COM NEW | 242,653 | $2,863,305 | dollars as filed | |
| SPRINGWORKS THERAPEUTICS INC | 85205L107 | COM | 74,265 | $2,683,194 | dollars as filed | |
| ELEVATION ONCOLOGY INC COM | 28623U101 | Stock | 4,760,000 | $2,677,976 | dollars as filed | |
| JANUX THERAPEUTICS INC | 47103J105 | COM | 50,000 | $2,677,000 | dollars as filed | |
| PRECISION BIOSCIENCES INC | 74019P207 | COM NEW | 673,332 | $2,565,395 | dollars as filed | |
| ONKURE THERAPEUTICS INC | 68277Q105 | COM CL A | 294,626 | $2,533,784 | dollars as filed | |
| THERAVANCE BIOPHARMA INC | G8807B106 | COM | 262,896 | $2,473,851 | dollars as filed | |
| ATYR PHARMA INC | 002120202 | COM NEW | 671,134 | $2,429,505 | dollars as filed | |
| SOLENO THERAPEUTICS INC | 834203309 | COM | 50,000 | $2,247,500 | dollars as filed | |
| CAREDX INC | 14167L103 | COM | 100,000 | $2,141,000 | dollars as filed | |
| GENMAB A/S | 372303206 | Ordinary Shares, nominal value DKK 1 per share | 100,000 | $2,087,000 | dollars as filed | |
| Applied Therapeutics Inc | 03828A101 | Common Stock | 2,428,169 | $2,078,998 | dollars as filed | |
| IDEXX LABS INC COM | 45168D104 | Stock | 5,000 | $2,067,200 | dollars as filed | |
| BOLT BIOTHERAPEUTICS INC | 097702104 | COM | 3,812,773 | $2,040,215 | dollars as filed | |
| FORTREA HLDGS INC COMMON STOCK | 34965K107 | Stock | 100,000 | $1,865,000 | dollars as filed | |
| ITEOS THERAPEUTICS INC | 46565G104 | COM | 221,716 | $1,702,779 | dollars as filed | |
| JPMorgan Chase & Co | 46625H100 | COM | 6,601 | $1,582,444 | dollars as filed | |
| Walmart Inc. | 931142103 | COM | 17,423 | $1,574,211 | dollars as filed | |
| THIRD HARMONIC BIO INC | 88427A107 | COM | 150,000 | $1,543,500 | dollars as filed | |
| ERASCA INC COM | 29479A108 | Stock | 602,915 | $1,513,317 | dollars as filed | |
| Visa Inc | 92826C839 | COM | 4,718 | $1,490,948 | dollars as filed | |
| Walt Disney Co | 254687106 | COM | 13,095 | $1,458,129 | dollars as filed | |
| Microsoft Corp | 594918104 | COM | 3,413 | $1,438,443 | dollars as filed | |
| REGENERON PHARMACEUTICALS COM | 75886F107 | Stock | 2,000 | $1,424,660 | dollars as filed | |
| VIATRIS INC COM | 92556V106 | Stock | 114,316 | $1,423,240 | dollars as filed | |
| Berkshire Hathaway Inc | 084670702 | COM | 3,099 | $1,404,653 | dollars as filed | |
| VERASTEM INC | 92337C203 | COMMON STOCK | 270,000 | $1,395,900 | dollars as filed | |
| MIND MEDICINE MINDMED INC | 60255C885 | COM NEW | 200,000 | $1,392,000 | dollars as filed | |
| PAYPALHLDGSINC | 70450Y103 | STOK | 15,714 | $1,341,174 | dollars as filed | |
| Procter & Gamble Co | 742718109 | COM | 7,962 | $1,334,837 | dollars as filed | |
| SYNDAX PHARMACEUTICALS INC | 87164F105 | COM | 100,000 | $1,322,000 | dollars as filed | |
| Home Depot, Inc | 437076102 | COM | 3,353 | $1,304,211 | dollars as filed | |
| BEAM THERAPEUTICS INC | 07373V105 | COM | 50,000 | $1,240,000 | dollars as filed | |
| Verizon Communications Inc | 92343V104 | COM | 30,877 | $1,234,778 | dollars as filed | |
| Texas Instruments Incorporated | 882508104 | COM | 6,568 | $1,231,538 | dollars as filed | |
| Coca-Cola Company | 191216100 | COM | 19,714 | $1,227,386 | dollars as filed | |
| UNITED AIRLS HLDGS INC COM | 910047109 | Stock | 12,392 | $1,203,258 | dollars as filed | |
| Netflix, Inc | 64110L106 | COM | 1,344 | $1,197,944 | dollars as filed | |
| NIKE,Inc. Class B | 654106103 | COM | 15,789 | $1,194,731 | dollars as filed | |
| EXXON MOBIL CORP | 30231G102 | COM | 11,053 | $1,188,967 | dollars as filed | |
| ULTA BEAUTY INC COM | 90384S303 | Stock | 2,699 | $1,173,838 | dollars as filed | |
| UnitedHealth Group Inc | 91324P102 | COM | 2,308 | $1,167,741 | dollars as filed | |
| Johnson & Johnson | 478160104 | COM | 7,959 | $1,151,039 | dollars as filed | |
| Pfizer Inc. | 717081103 | COM | 42,908 | $1,138,344 | dollars as filed | |
| American Express Company | 025816109 | COM | 3,799 | $1,127,517 | dollars as filed | |
| Intel Corp | 458140100 | COM | 55,997 | $1,122,739 | dollars as filed | |
| Boeing Company | 097023105 | COM | 6,294 | $1,113,989 | dollars as filed | |
| Amazon.com, Inc | 023135106 | COM | 5,071 | $1,112,593 | dollars as filed | |
| OPTIMIZERX CORP | 68401U204 | COM NEW | 221,200 | $1,075,032 | dollars as filed | |
| OMNIAB INC | 68218J103 | COM | 300,000 | $1,062,000 | dollars as filed | |
| ALLSTATE CORP COM | 020002101 | Stock | 5,319 | $1,025,424 | dollars as filed | |
| ATARA BIOTHERAPEUTICS INC | 046513206 | COM NEW | 75,196 | $1,000,859 | dollars as filed | |
| HORMEL FOODS CORP COM | 440452100 | Stock | 31,741 | $995,706 | dollars as filed | |
| T-Mobile US,Inc. | 872590104 | COM | 4,509 | $995,356 | dollars as filed | |
| HEWLETT PACKARD ENTERPRISE CO COM | 42824C109 | Stock | 46,391 | $990,452 | dollars as filed | |
| General Electric Company | 369604301 | COM | 5,911 | $985,972 | dollars as filed | |
| PAYCHEX INC | 704326107 | COM | 6,973 | $977,802 | dollars as filed | |
| CLOROX CO DEL | 189054109 | COM | 6,014 | $976,676 | dollars as filed | |
| McDonalds Corporation | 580135101 | COM | 3,365 | $975,499 | dollars as filed | |
| WHIRLPOOL CORP COM | 963320106 | Stock | 8,510 | $974,215 | dollars as filed | |
| KRONOS BIO INC | 50107A104 | COM | 1,003,382 | $953,213 | dollars as filed | |
| SEALED AIR CORP NEW | 81211K100 | COM | 28,132 | $951,719 | dollars as filed | |
| FEDEX CORP COM | 31428X106 | Stock | 3,349 | $942,208 | dollars as filed | |
| SHERWIN WILLIAMS CO | 824348106 | COM | 2,765 | $939,753 | dollars as filed | |
| CENTURY THERAPEUTICS INC | 15673T100 | COM | 900,000 | $909,000 | dollars as filed | |
| ASTRIA THERAPEUTICS INC COM | 04635X102 | Stock | 100,000 | $894,000 | dollars as filed | |
| GE Vernova Inc. | 36828A101 | COM | 2,710 | $891,379 | dollars as filed | |
| MARINUS PHARMACEUTICALS INC | 56854Q200 | COM NEW | 1,641,945 | $878,605 | dollars as filed | |
| KURA ONCOLOGY INC COM | 50127T109 | Stock | 100,000 | $871,000 | dollars as filed | |
| Chevron Corporation | 166764100 | COM | 5,978 | $865,854 | dollars as filed | |
| PASSAGE BIO INC | 702712100 | COM | 1,500,000 | $850,650 | dollars as filed | |
| FORD MTR CO COM | 345370860 | Stock | 85,749 | $848,916 | dollars as filed | |
| BIOATLA INC | 09077B104 | COM | 1,374,076 | $812,354 | dollars as filed | |
| ENANTA PHARMACEUTICALS INC | 29251M106 | COM | 126,655 | $728,266 | dollars as filed | |
| STANDARD BIOTOOLS INC | 34385P108 | COM | 407,755 | $713,571 | dollars as filed | |
| MACROGENICS INC | 556099109 | COM | 218,856 | $711,282 | dollars as filed | |
| LEXICON PHARMACEUTICALS INC | 528872302 | COMMON STOCK | 850,268 | $627,923 | dollars as filed | |
| PUMA BIOTECHNOLOGY INC | 74587V107 | COMMON STOCK | 200,000 | $610,000 | dollars as filed | |
| NEXTCURE INC | 65343E108 | COM | 700,000 | $539,700 | dollars as filed | |
| EDITAS MEDICINE INC | 28106W103 | COM | 400,000 | $508,000 | dollars as filed | |
| ALLAKOS INC | 01671P100 | COM | 378,552 | $458,048 | dollars as filed | |
| AMYLYX PHARMACEUTICALS INC | 03237H101 | COM | 100,000 | $378,000 | dollars as filed | |
| Tscan Therapeutics Inc | 89854M101 | COM | 117,847 | $358,255 | dollars as filed | |
| ATHIRA PHARMA INC | 04746L104 | COM | 600,000 | $352,020 | dollars as filed | |
| OUTLOOK THERAPEUTICS INC | 69012T305 | COM | 182,502 | $344,929 | dollars as filed | |
| Reviva Pharmaceuticals Holdings Inc | 76152G100 | Common Stock | 170,000 | $307,700 | dollars as filed | |
| ALLOVIR INC | 019818103 | COM | 552,264 | $231,951 | dollars as filed | |
| AFFIMED N V | N01045207 | COM | 148,315 | $176,495 | dollars as filed | |
| INVIVYD INC | 00534A102 | COMMON STOCK | 330,172 | $146,299 | dollars as filed | |
| RELMADA THERAPEUTICS INC | 75955J402 | COMMON STOCK | 200,825 | $104,429 | dollars as filed | |
| IMMUNEERING CORP | 45254E107 | CLASS A COM | 12,073 | $26,561 | dollars as filed |
Amendment chain
| Filing | Role | Filed | Accepted | Ingested |
|---|---|---|---|---|
| 13F-HR 0001214659-25-002812 | this filing | 2025-02-14 | acceptance time not in the bulk data set |