13F-HR filed by Opaleye Management Inc.
Opaleye Management Inc. filed this 13F-HR for the quarter ended 2024-12-31, filed 2025-02-14, with 39 holding rows worth $571,422,527.
- Accession
- 0001493152-25-006852
- Filer
- CIK 1595855
- Filed
- 2025-02-14
- Accepted by EDGAR
- acceptance time not in the bulk data set
- Ingested
- Source
- SEC quarterly data set
13F report for Q4 2024
A holdings report, 39 entries on the cover page, a total value of $571,422,527 stated on the cover page (in dollars after the unit check, H1), rows summing to $571,422,527 with VALUE read as dollars as filed, 13F file number 028-15896. The quarter's positions are built on this report. The resolved quarter.
The information table after summing rows of one CUSIP and put or call (H4), with the CUSIP and issuer name as filed. Values in dollars after the unit check (method).
| Issuer as filed | CUSIP | Class | Amount | Value | Value read as | Type |
|---|---|---|---|---|---|---|
| HARROW INC | 415858109 | COM | 3,990,000 | $133,864,500 | dollars as filed | |
| TG THERAPEUTICS INC COM | 88322Q108 | Stock | 2,260,000 | $68,026,000 | dollars as filed | |
| CODEXIS INC | 192005106 | COM | 8,840,000 | $42,166,800 | dollars as filed | |
| ETON PHARMACEUTICALS INC | 29772L108 | COMMON STOCK | 2,852,070 | $37,989,572 | dollars as filed | |
| OCULAR THERAPEUTIX INC | 67576A100 | COM | 4,342,500 | $37,084,950 | dollars as filed | |
| ARVINAS INC | 04335A105 | COM | 1,625,000 | $33,643,350 | dollars as filed | |
| RHYTHM PHARMACEUTICALS INC | 76243J105 | COM | 500,000 | $27,990,000 | dollars as filed | |
| IMMUNOME INC | 45257U108 | COM | 2,040,000 | $21,664,800 | dollars as filed | |
| LIQUIDIA CORPORATION COM NEW | 53635D202 | Stock | 1,698,142 | $19,970,150 | dollars as filed | |
| EDGEWISE THERAPEUTICS INC | 28036F105 | COM | 480,000 | $12,816,000 | dollars as filed | |
| GINKGO BIOWORKS HOLDINGS INC | 37611X209 | COMMON STOCK | 1,200,000 | $11,784,000 | dollars as filed | |
| CARGO THERAPEUTICS INC COM | 14179K101 | Stock | 750,000 | $10,815,000 | dollars as filed | |
| PROTARA THERAPEUTICS INC | 74365U107 | COM STK | 1,825,000 | $9,636,000 | dollars as filed | |
| TREVI THERAPEUTICS INC COM | 89532M101 | Stock | 2,317,500 | $9,548,100 | dollars as filed | |
| JASPER THERAPEUTICS INC | 471871202 | COM NEW | 400,000 | $8,552,000 | dollars as filed | |
| NEWAMSTERDAM PHARMA CO NV | N62509109 | COMMON STOCK | 325,000 | $8,352,500 | dollars as filed | |
| ACELYRIN INC | 00445A100 | COM | 2,235,000 | $7,174,900 | dollars as filed | |
| NURIX THERAPEUTICS INC | 67080M103 | COMMON STOCK | 378,500 | $7,130,940 | dollars as filed | |
| XOMA ROYALTY CORPORATION | 98419J206 | COMMON STOCK | 250,000 | $6,570,000 | dollars as filed | |
| VAXCYTE INC COM | 92243G108 | Stock | 75,000 | $6,139,500 | dollars as filed | |
| GOSSAMER BIO INC | 38341PAA0 | NOTE 5.000% 6/0 | 11,500,000 | $6,090,400 | dollars as filed | principal |
| ZENTALIS PHARMACEUTICALS INC | 98943L107 | COMMON STOCK | 1,767,500 | $5,355,525 | dollars as filed | |
| BIODESIX INC | 09075X108 | COM | 3,465,000 | $5,301,450 | dollars as filed | |
| KARYOPHARM THERAPEUTICS INC | 48576UAA4 | BOND | 6,000,000 | $4,669,560 | dollars as filed | principal |
| NUVALENT INC COM | 670703107 | Stock | 58,500 | $4,579,380 | dollars as filed | |
| GOSSAMER BIO INC COM | 38341P102 | Stock | 4,490,000 | $4,061,654 | dollars as filed | |
| PROTAGONIST THERAPEUTICS | 74366E102 | COM | 105,000 | $4,053,000 | dollars as filed | |
| ESSA PHARMA INC | 29668H708 | COM NEW | 2,209,998 | $3,955,896 | dollars as filed | |
| ABCELLERA BIOLOGICS INC COM | 00288U106 | Stock | 965,000 | $2,827,450 | dollars as filed | |
| UROGEN PHARMA LTD | M96088105 | COMMON STOCK | 220,000 | $2,343,000 | dollars as filed | |
| REZOLUTE INC | 76200L309 | COMMON STOCK | 465,000 | $2,278,500 | dollars as filed | |
| IMMATICS N.V | N44445109 | SHS | 165,000 | $1,173,150 | dollars as filed | |
| IBIO INC | 451033708 | CMN | 375,000 | $918,750 | dollars as filed | |
| LEXEO THERAPEUTICS INC | 52886X107 | COMMON STOCK | 130,000 | $855,400 | dollars as filed | |
| REGENXBIO INC | 75901B107 | COM | 80,000 | $618,400 | dollars as filed | |
| Ventyx Biosciences Inc | 92332V107 | Common Stock | 280,000 | $613,200 | dollars as filed | |
| PEPGEN INC COM | 713317105 | Stock | 110,000 | $416,900 | dollars as filed | |
| STOKE THERAPEUTICS INC | 86150R107 | COM | 25,000 | $275,750 | dollars as filed | |
| Adagio Med Hldgs Inc Com | 00534B100 | Common Stock | 110,571 | $116,100 | dollars as filed |
Amendment chain
| Filing | Role | Filed | Accepted | Ingested |
|---|---|---|---|---|
| 13F-HR 0001493152-25-006852 | this filing | 2025-02-14 | acceptance time not in the bulk data set |