VANGUARD GROUP INC group of 7 filers holding More: the full row for VANGUARD GROUP INC 17,239,140 $1.68B +17,225,771 Timeline VANGUARD CAPITAL MANAGEMENT LLC : 8,362,284 (0.02%) 13F-HR/A VANGUARD PORTFOLIO MANAGEMENT LLC : 7,502,623 (0.04%) 13F-HR VANGUARD FIDUCIARY TRUST CO : 1,133,319 (0.03%) 13F-HR VANGUARD ASSET MANAGEMENT, Ltd : 80,514 (0.01%) 13F-HR Vanguard Global Advisers, LLC : 78,482 (<0.01%) 13F-HR Vanguard Investments Australia, L… : 67,421 (0.02%) 13F-HR Vanguard Personalized Indexing Ma… : 14,497 (0.01%) 13F-HR FARALLON CAPITAL MANAGEMENT, L.L.C. More: the full row for FARALLON CAPITAL MANAGEMENT, L.L.C. 13,604,796 $1.32B 7.84% -978,000 13F-HR Timeline The filing omitted confidential holdings, a later amendment may add them. BlackRock, Inc. in group BlackRock, Inc. More: the full row for BlackRock, Inc. 11,212,706 $1.09B 0.02% +2,286,050 13F-HR Timeline Group JANUS HENDERSON GROUP PLC in group Janus Henderson More: the full row for JANUS HENDERSON GROUP PLC 9,766,496 $950M 0.45% -2,537,006 13F-HR/A Timeline Group BAKER BROS. ADVISORS LP in group BAKER BROS. ADVISORS LP More: the full row for BAKER BROS. ADVISORS LP 9,555,357 $929M 5.34% +100,000 13F-HR Timeline Group FMR LLC in group FMR LLC More: the full row for FMR LLC 8,464,314 $823M 0.04% -123,667 13F-HR Timeline Group Nextech Invest Ltd. More: the full row for Nextech Invest Ltd. 7,601,087 $739M 52.02% 0 13F-HR Timeline Paradigm Biocapital Advisors LP in group Paradigm Biocapital Advisors … More: the full row for Paradigm Biocapital Advisors LP 6,655,703 $647M 13.23% +11,300 13F-HR Timeline Group WELLINGTON MANAGEMENT GROUP LLP in group WELLINGTON MANAGEMENT GROUP L… More: the full row for WELLINGTON MANAGEMENT GROUP LLP 6,027,819 $586M 0.11% -959,820 13F-HR Timeline Group ADAGE CAPITAL PARTNERS GP, L.L.C. in group ADAGE CAPITAL PARTNERS GP, L.… More: the full row for ADAGE CAPITAL PARTNERS GP, L.L.C. 5,475,611 $533M 0.82% +3,270,056 13F-HR Timeline Group UBS Group AG group of 2 filers holding More: the full row for UBS Group AG 4,887,386 $475M +1,450,037 Timeline STATE STREET CORP in group STATE STREET CORP More: the full row for STATE STREET CORP 4,402,662 $428M 0.01% +293,372 13F-HR Timeline Group GEODE CAPITAL MANAGEMENT, LLC in group GEODE CAPITAL MANAGEMENT, LLC More: the full row for GEODE CAPITAL MANAGEMENT, LLC 3,338,142 $324M 0.02% +176,179 13F-HR Timeline Group Alphabet Inc. in group Alphabet Inc. More: the full row for Alphabet Inc. 3,292,525 $320M 7.97% -52,577 13F-HR Timeline Group PRICE T ROWE ASSOCIATES INC /MD/ More: the full row for PRICE T ROWE ASSOCIATES INC /MD/ 3,232,213 $314M 0.04% -172,504 13F-HR Timeline BVF INC/IL in group BVF INC/IL More: the full row for BVF INC/IL 2,856,782 $278M 8.85% -500,000 13F-HR Timeline Group Casdin Capital, LLC More: the full row for Casdin Capital, LLC 2,577,333 $251M 18.98% 0 13F-HR Timeline Woodline Partners LP More: the full row for Woodline Partners LP 2,506,570 $244M 0.92% +5,675 13F-HR/A Timeline Holocene Advisors, LP More: the full row for Holocene Advisors, LP 2,468,644 $240M 0.58% +560,696 13F-HR Timeline Vestal Point Capital, LP More: the full row for Vestal Point Capital, LP 2,375,000 $231M 6.46% +2,080,000 13F-HR Timeline Avoro Capital Advisors LLC More: the full row for Avoro Capital Advisors LLC 2,344,444 $228M 2.25% +174,444 13F-HR Timeline DEERFIELD MANAGEMENT COMPANY, L.P. in group DEERFIELD MANAGEMENT COMPANY,… More: the full row for DEERFIELD MANAGEMENT COMPANY, L.P. 2,297,000 $223M 2.64% -597,613 13F-HR Timeline Group GOLDMAN SACHS GROUP INC in group GOLDMAN SACHS GROUP INC More: the full row for GOLDMAN SACHS GROUP INC 2,185,500 $213M 0.03% -306,083 13F-HR Timeline Group Darwin Global Management, Ltd. in group Darwin Global Management, Ltd. More: the full row for Darwin Global Management, Ltd. 2,211,018 $205M 5.44% new 13F-HR Timeline Group Logos Global Management LP More: the full row for Logos Global Management LP 2,000,000 $194M 10.02% 0 13F-HR Timeline Alyeska Investment Group, L.P. in group Alyeska Investment Group, L.P. More: the full row for Alyeska Investment Group, L.P. 1,885,821 $183M 0.52% +1,646,724 13F-HR Timeline Group NATIONAL BANK OF CANADA /FI/ in group NATIONAL BANK OF CANADA /FI/ More: the full row for NATIONAL BANK OF CANADA /FI/ 1,749,000 $170M 0.17% new 13F-HR Timeline Group CHARLES SCHWAB INVESTMENT MANAGEMENT INC in group Charles Schwab Trust Co More: the full row for CHARLES SCHWAB INVESTMENT MANAGEMENT INC 1,735,476 $169M 0.03% +51,747 13F-HR Timeline Group Caligan Partners LP More: the full row for Caligan Partners LP 1,652,808 $161M 11.37% +368,908 13F-HR Timeline AMERIPRISE FINANCIAL INC in group AMERIPRISE FINANCIAL INC More: the full row for AMERIPRISE FINANCIAL INC 1,579,793 $154M 0.04% -477,064 13F-HR/A Timeline Group TWO SIGMA INVESTMENTS, LP in group TWO SIGMA INVESTMENTS, LP More: the full row for TWO SIGMA INVESTMENTS, LP 1,558,807 $152M 0.13% +1,137,072 13F-HR Timeline Group WESTFIELD CAPITAL MANAGEMENT CO LP More: the full row for WESTFIELD CAPITAL MANAGEMENT CO LP 1,556,578 $151M 0.64% -1,288,435 13F-HR Timeline Bellevue Group AG in group Bellevue Group AG More: the full row for Bellevue Group AG 1,544,456 $150M 3.57% -3,461,263 13F-HR Timeline Group Integral Health Asset Management, LLC More: the full row for Integral Health Asset Management, LLC 1,500,000 $146M 7.72% +300,000 13F-HR Timeline Rock Springs Capital Management LP More: the full row for Rock Springs Capital Management LP 1,209,465 $118M 6.93% -125,805 13F-HR Timeline Polar Capital Holdings Plc in group Polar Capital Holdings Plc More: the full row for Polar Capital Holdings Plc 1,133,930 $110M 0.48% -879,861 13F-HR Timeline Group FRANKLIN RESOURCES INC in group Franklin Resources More: the full row for FRANKLIN RESOURCES INC 1,133,546 $110M 0.03% +73,375 13F-HR Timeline Group Siren, L.L.C. in group Siren, L.L.C. More: the full row for Siren, L.L.C. 1,110,980 $108M 3% -224,095 13F-HR Timeline Group a16z Capital Management, L.L.C. group of 2 filers holding More: the full row for a16z Capital Management, L.L.C. 1,025,313 $99.7M -78,704 Timeline D. E. Shaw & Co., Inc. in group D. E. Shaw & Co., Inc. More: the full row for D. E. Shaw & Co., Inc. 1,022,298 $99.4M 0.08% -591,432 13F-HR Timeline Group NORTHERN TRUST CORP in group NORTHERN TRUST CORP More: the full row for NORTHERN TRUST CORP 954,256 $92.8M 0.01% +103,933 13F-HR Timeline Group DIMENSIONAL FUND ADVISORS LP in group DIMENSIONAL FUND ADVISORS LP More: the full row for DIMENSIONAL FUND ADVISORS LP 844,614 $82.1M 0.02% -317,032 13F-HR Timeline Group AIHC Capital Management Ltd More: the full row for AIHC Capital Management Ltd 828,974 $80.6M 67.37% -71,418 13F-HR Timeline MIC Capital Management UK LLP More: the full row for MIC Capital Management UK LLP 795,733 $77.4M 21.95% +287,164 13F-HR Timeline GENERAL ATLANTIC, L.P. More: the full row for GENERAL ATLANTIC, L.P. 707,791 $68.8M 3.2% -2,105,137 13F-HR Timeline MORGAN STANLEY in group MORGAN STANLEY More: the full row for MORGAN STANLEY 705,793 $68.6M <0.01% +54,061 13F-HR Timeline Group Nearwater Capital Markets, Ltd More: the full row for Nearwater Capital Markets, Ltd 678,000 $65.9M 1.56% new 13F-HR Timeline Frazier Life Sciences Management, L.P. More: the full row for Frazier Life Sciences Management, L.P. 675,686 $65.7M 1.69% -121,769 13F-HR Timeline T. Rowe Price Investment Management, In… More: the full row for T. Rowe Price Investment Management, Inc. 664,047 $64.6M 0.04% -1,536,329 13F-HR Timeline Bank of New York Mellon Corp in group Bank of New York Mellon Corp More: the full row for Bank of New York Mellon Corp 635,366 $61.8M 0.01% +93,297 13F-HR Timeline Group WORLDQUANT MILLENNIUM ADVISORS LLC More: the full row for WORLDQUANT MILLENNIUM ADVISORS LLC 622,304 $60.5M 0.23% +528,294 13F-HR Timeline BANK OF AMERICA CORP /DE/ in group BANK OF AMERICA CORP /DE/ More: the full row for BANK OF AMERICA CORP /DE/ 614,157 $59.7M <0.01% -265,688 13F-HR Timeline Group DAFNA Capital Management LLC More: the full row for DAFNA Capital Management LLC 580,678 $56.5M 12.85% -23,836 13F-HR Timeline Candriam S.C.A. More: the full row for Candriam S.C.A. 580,677 $56.5M 0.29% -450,315 13F-HR Timeline TCG Crossover Management, LLC More: the full row for TCG Crossover Management, LLC 576,473 $56.1M 1.6% +140,000 13F-HR Timeline Qube Research & Technologies Ltd More: the full row for Qube Research & Technologies Ltd 553,290 $53.8M 0.08% new 13F-HR Timeline Pictet Asset Management Holding SA in group Pictet Asset Management Holdi… More: the full row for Pictet Asset Management Holding SA 557,560 $53.6M 0.06% -579,561 13F-HR Timeline Group Lunate Capital Ltd in group Lunate Capital Ltd More: the full row for Lunate Capital Ltd 549,050 $53.4M 44.36% -1,647,150 13F-HR Timeline Group MPM BIOIMPACT LLC More: the full row for MPM BIOIMPACT LLC 506,776 $49.3M 3.81% +1,104 13F-HR Timeline Boxer Capital Management, LLC in group Boxer Capital Management, LLC More: the full row for Boxer Capital Management, LLC 500,000 $48.6M 6.38% +100,000 13F-HR Timeline Group Nationale-Nederlanden Powszechne Towarz… More: the full row for Nationale-Nederlanden Powszechne Towarzystwo Emerytalne S.A. 479,080 $46.6M 3.95% new 13F-HR Timeline First Turn Management, LLC More: the full row for First Turn Management, LLC 468,376 $45.5M 5.09% -170,009 13F-HR Timeline DEUTSCHE BANK AG\ in group DEUTSCHE BANK AG\ More: the full row for DEUTSCHE BANK AG\ 465,758 $45.3M 0.01% +433,541 13F-HR Timeline Group BOOTHBAY FUND MANAGEMENT, LLC More: the full row for BOOTHBAY FUND MANAGEMENT, LLC 438,595 $42.7M 0.98% +111,443 13F-HR Timeline Swiss National Bank More: the full row for Swiss National Bank 425,431 $41.4M 0.02% +149,100 13F-HR Timeline BNP PARIBAS FINANCIAL MARKETS in group BNP PARIBAS FINANCIAL MARKETS More: the full row for BNP PARIBAS FINANCIAL MARKETS 422,443 $41.1M 0.03% -196,944 13F-HR Timeline Group CITADEL ADVISORS LLC in group CITADEL ADVISORS LLC More: the full row for CITADEL ADVISORS LLC 400,053 $38.9M 0.03% -902,308 13F-HR Timeline Group Invesco Ltd. in group Invesco Ltd. More: the full row for Invesco Ltd. 392,844 $38.2M <0.01% +24,993 13F-HR Timeline Group BARCLAYS PLC in group BARCLAYS PLC More: the full row for BARCLAYS PLC 383,179 $37.3M 0.01% +247,131 13F-HR Timeline Group MILLENNIUM MANAGEMENT LLC in group MILLENNIUM MANAGEMENT LLC More: the full row for MILLENNIUM MANAGEMENT LLC 377,332 $36.7M 0.03% -422,786 13F-HR Timeline Group SAMLYN CAPITAL, LLC in group SAMLYN CAPITAL, LLC More: the full row for SAMLYN CAPITAL, LLC 371,948 $36.2M 0.62% new 13F-HR Timeline Group ROYAL BANK OF CANADA in group ROYAL BANK OF CANADA More: the full row for ROYAL BANK OF CANADA 371,743 $36.2M 0.01% -131,978 13F-HR Timeline Group VOLORIDGE INVESTMENT MANAGEMENT, LLC More: the full row for VOLORIDGE INVESTMENT MANAGEMENT, LLC 368,325 $35.8M 0.14% +46,036 13F-HR Timeline Mass General Brigham, Inc More: the full row for Mass General Brigham, Inc 344,091 $33.5M 7.14% 0 13F-HR Timeline Legal & General Group Plc in group Legal & General Group Plc More: the full row for Legal & General Group Plc 341,148 $33.2M 0.01% +187,768 13F-HR Timeline Group Nuveen, LLC in group TIAA More: the full row for Nuveen, LLC 340,611 $33.1M 0.01% -65,630 13F-HR Timeline Group AMERICAN CENTURY COMPANIES INC in group AMERICAN CENTURY COMPANIES INC More: the full row for AMERICAN CENTURY COMPANIES INC 335,528 $32.6M 0.02% -131,832 13F-HR Timeline Group TD Asset Management Inc More: the full row for TD Asset Management Inc 317,811 $30.9M 0.03% -52,709 13F-HR Timeline Defilade Capital Management, L.P. More: the full row for Defilade Capital Management, L.P. 315,972 $30.7M 4.31% -47,482 13F-HR/A Timeline Duquesne Family Office LLC More: the full row for Duquesne Family Office LLC 315,860 $30.7M 1.05% new 13F-HR Timeline JENNISON ASSOCIATES LLC More: the full row for JENNISON ASSOCIATES LLC 307,377 $29.9M 0.02% +2,117 13F-HR Timeline JPMORGAN CHASE & CO in group JPMORGAN CHASE & CO More: the full row for JPMORGAN CHASE & CO 301,393 $27.9M <0.01% -120,234 13F-HR/A Timeline Group California Public Employees Retirement … More: the full row for California Public Employees Retirement System 281,960 $27.4M 0.02% -9,046 13F-HR Timeline STEMPOINT CAPITAL LP More: the full row for STEMPOINT CAPITAL LP 281,632 $27.4M 5.26% +219,600 13F-HR/A Timeline Man Group plc in group Man Group plc More: the full row for Man Group plc 275,270 $26.8M 0.06% +177,765 13F-HR Timeline Group Mitsubishi UFJ Trust & Banking Corp group of 3 filers holding More: the full row for Mitsubishi UFJ Trust & Banking Corp 272,805 $26.5M +118,291 Timeline Sumitomo Mitsui Trust Group, Inc. in group Sumitomo Mitsui Trust Group, … More: the full row for Sumitomo Mitsui Trust Group, Inc. 270,972 $26.4M 0.02% +265,474 13F-HR Timeline Group Melqart Asset Management (UK) Ltd More: the full row for Melqart Asset Management (UK) Ltd 270,363 $26.3M 2.59% new 13F-HR Timeline Checkpoint Capital L.P. More: the full row for Checkpoint Capital L.P. 262,539 $25.5M 9.16% -107,461 13F-HR Timeline EVENTIDE ASSET MANAGEMENT, LLC More: the full row for EVENTIDE ASSET MANAGEMENT, LLC 261,425 $25.4M 0.42% -116,836 13F-HR Timeline Nicholas Investment Partners, LP More: the full row for Nicholas Investment Partners, LP 261,166 $25.4M 1.83% -56,545 13F-HR Timeline PERCEPTIVE ADVISORS LLC in group PERCEPTIVE ADVISORS LLC More: the full row for PERCEPTIVE ADVISORS LLC 258,600 $25.1M 0.5% new 13F-HR/A Timeline Group Trails Edge Capital Partners, LP More: the full row for Trails Edge Capital Partners, LP 245,000 $23.8M 5.61% new 13F-HR Timeline FRONTIER CAPITAL MANAGEMENT CO LLC More: the full row for FRONTIER CAPITAL MANAGEMENT CO LLC 243,804 $23.7M 0.24% -186,964 13F-HR Timeline Ensign Peak Advisors, Inc More: the full row for Ensign Peak Advisors, Inc 227,940 $22.2M 0.04% -7,868 13F-HR/A Timeline MARSICO CAPITAL MANAGEMENT LLC More: the full row for MARSICO CAPITAL MANAGEMENT LLC 219,460 $21.3M 0.63% 0 13F-HR Timeline MARSHALL WACE, LLP in group MARSHALL WACE, LLP More: the full row for MARSHALL WACE, LLP 216,661 $21.1M 0.02% -169,530 13F-HR Timeline Group Fisher Asset Management, LLC More: the full row for Fisher Asset Management, LLC 215,947 $21M 0.01% -25,110 13F-HR Timeline Abu Dhabi Investment Council Co P.J.S.C in group Abu Dhabi Investment Council … More: the full row for Abu Dhabi Investment Council Co P.J.S.C 1,739,859 $19.1M 1.96% 13F-HR Timeline Group BAILLIE GIFFORD & CO in group BAILLIE GIFFORD & CO More: the full row for BAILLIE GIFFORD & CO 187,072 $18.2M 0.02% -7,887 13F-HR Timeline Group RHUMBLINE ADVISERS More: the full row for RHUMBLINE ADVISERS 179,942 $17.5M 0.01% +19,494 13F-HR Timeline CALIFORNIA STATE TEACHERS RETIREMENT SY… More: the full row for CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 165,277 $16.1M 0.02% +29,887 13F-HR Timeline Ikarian Capital, LLC in group Ikarian Capital, LLC More: the full row for Ikarian Capital, LLC 163,142 $15.9M 2.27% +25,000 13F-HR Timeline Group Birnam Oak Advisors, LP More: the full row for Birnam Oak Advisors, LP 159,413 $15.5M 4.27% new 13F-HR Timeline STATE BOARD OF ADMINISTRATION OF FLORID… More: the full row for STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM 144,882 $14.1M 0.03% +13,946 13F-HR Timeline VICTORY CAPITAL MANAGEMENT INC More: the full row for VICTORY CAPITAL MANAGEMENT INC 142,578 $13.9M 0.01% +3,266 13F-HR Timeline MANUFACTURERS LIFE INSURANCE COMPANY, T… in group MANUFACTURERS LIFE INSURANCE … More: the full row for MANUFACTURERS LIFE INSURANCE COMPANY, THE 141,296 $13.7M 0.01% -30,247 13F-HR Timeline Group PFM Health Sciences, LP More: the full row for PFM Health Sciences, LP 140,770 $13.7M 1.44% -10,683 13F-HR Timeline Amundi in group Amundi More: the full row for Amundi 138,560 $13.5M <0.01% +118,493 13F-HR Timeline Group PSquared Asset Management AG More: the full row for PSquared Asset Management AG 138,290 $13.4M 4.68% new 13F-HR Timeline RAYMOND JAMES FINANCIAL INC in group RAYMOND JAMES FINANCIAL INC More: the full row for RAYMOND JAMES FINANCIAL INC 137,160 $13.3M <0.01% -107,014 13F-HR Timeline Group Tidal Investments LLC in group Tidal Investments LLC More: the full row for Tidal Investments LLC 137,242 $13.2M 0.04% new 13F-HR Timeline Group LORD, ABBETT & CO. LLC More: the full row for LORD, ABBETT & CO. LLC 134,233 $13.1M 0.04% -265,251 13F-HR Timeline ADAR1 Capital Management, LLC in group ADAR1 Capital Management, LLC More: the full row for ADAR1 Capital Management, LLC 133,893 $13M 0.78% -11,186 13F-HR Timeline Group LMR Partners LLP in group LMR Partners LLP More: the full row for LMR Partners LLP 130,000 $12.6M 0.12% new 13F-HR Timeline Group Gotham Asset Management, LLC More: the full row for Gotham Asset Management, LLC 125,901 $12.2M 0.04% +12,072 13F-HR Timeline Artia Global Partners LP More: the full row for Artia Global Partners LP 124,990 $12.2M 2.74% +20,800 13F-HR Timeline NEW YORK STATE COMMON RETIREMENT FUND More: the full row for NEW YORK STATE COMMON RETIREMENT FUND 124,709 $12.1M 0.02% -4,698 13F-HR Timeline Squarepoint Ops LLC in group Squarepoint Ops LLC More: the full row for Squarepoint Ops LLC 120,769 $11.7M 0.03% +97,134 13F-HR Timeline Group Eagle Health Investments LP More: the full row for Eagle Health Investments LP 119,464 $11.6M 2.44% +3,564 13F-HR Timeline AQR CAPITAL MANAGEMENT LLC in group AQR CAPITAL MANAGEMENT LLC More: the full row for AQR CAPITAL MANAGEMENT LLC 116,787 $11.4M 0.01% -10,383 13F-HR Timeline Group Aberdeen Group plc in group Aberdeen Group plc More: the full row for Aberdeen Group plc 114,767 $11.2M 0.02% +1,499 13F-HR Timeline Group Verition Fund Management LLC More: the full row for Verition Fund Management LLC 110,000 $10.7M 0.1% -79,333 13F-HR Timeline VAN ECK ASSOCIATES CORP in group VAN ECK ASSOCIATES CORP More: the full row for VAN ECK ASSOCIATES CORP 109,365 $10.6M 0.01% new 13F-HR Timeline Group BNP PARIBAS ASSET MANAGEMENT Holding S.… in group BNP PARIBAS ASSET MANAGEMENT … More: the full row for BNP PARIBAS ASSET MANAGEMENT Holding S.A. 106,498 $10.4M 0.01% +2,946 13F-HR Timeline Group ING GROEP NV More: the full row for ING GROEP NV 103,000 $10M 0.06% new 13F-HR Timeline Empyrean Capital Partners, LP More: the full row for Empyrean Capital Partners, LP 102,400 $9.96M 0.33% new 13F-HR Timeline WCM INVESTMENT MANAGEMENT, LLC More: the full row for WCM INVESTMENT MANAGEMENT, LLC 104,989 $9.73M 0.02% -12,226 13F-HR Timeline Opaleye Management Inc. More: the full row for Opaleye Management Inc. 100,000 $9.72M 1.28% 0 13F-HR Timeline Affinity Asset Advisors, LLC More: the full row for Affinity Asset Advisors, LLC 100,000 $9.72M 0.57% 0 13F-HR Timeline Russell Investments Group, Ltd. in group Russell Investments Group, Lt… More: the full row for Russell Investments Group, Ltd. 99,117 $9.64M 0.01% +237 13F-HR Timeline Group Tema ETFs LLC More: the full row for Tema ETFs LLC 98,178 $9.55M 0.64% -2,425 13F-HR Timeline Cinctive Capital Management LP More: the full row for Cinctive Capital Management LP 93,857 $9.13M 0.6% +51,222 13F-HR Timeline Decheng Capital LLC More: the full row for Decheng Capital LLC 93,500 $9.09M 1.37% -106,500 13F-HR Timeline Atle Fund Management AB More: the full row for Atle Fund Management AB 617,245 $9.08M 2.93% +527,061 13F-HR Timeline Connor, Clark & Lunn Investment Managem… More: the full row for Connor, Clark & Lunn Investment Management Ltd. 91,720 $8.92M 0.02% new 13F-HR Timeline CITIGROUP INC in group CITIGROUP INC More: the full row for CITIGROUP INC 89,742 $8.73M 0.01% +44,040 13F-HR Timeline Group CANADA PENSION PLAN INVESTMENT BOARD More: the full row for CANADA PENSION PLAN INVESTMENT BOARD 89,000 $8.66M 0.01% -19,675 13F-HR Timeline TUDOR INVESTMENT CORP ET AL More: the full row for TUDOR INVESTMENT CORP ET AL 87,852 $8.54M 0.05% -4,539 13F-HR Timeline BRAIDWELL LP More: the full row for BRAIDWELL LP 84,900 $8.26M 0.28% new 13F-HR Timeline STATE OF WISCONSIN INVESTMENT BOARD More: the full row for STATE OF WISCONSIN INVESTMENT BOARD 83,681 $8.14M 0.02% -14,123 13F-HR Timeline DIADEMA PARTNERS LP More: the full row for DIADEMA PARTNERS LP 80,872 $7.86M 3.25% +43,852 13F-HR Timeline Seven Fleet Capital Management LP More: the full row for Seven Fleet Capital Management LP 80,792 $7.86M 2.47% +14,992 13F-HR/A Timeline ALGERT GLOBAL LLC More: the full row for ALGERT GLOBAL LLC 75,020 $7.3M 0.11% -38,910 13F-HR/A Timeline M&G PLC in group M&G PLC More: the full row for M&G PLC 74,733 $7.25M 0.04% -14,219 13F-HR Timeline Group Police & Firemen's Retirement System of… More: the full row for Police & Firemen's Retirement System of New Jersey 72,830 $7.08M 0.06% -367 13F-HR Timeline Treasurer of the State of North Carolina More: the full row for Treasurer of the State of North Carolina 72,820 $7.08M 0.02% +203 13F-HR Timeline FIRST TRUST ADVISORS LP in group FIRST TRUST ADVISORS LP More: the full row for FIRST TRUST ADVISORS LP 70,970 $6.9M <0.01% +31,605 13F-HR Timeline Group SEB Asset Management AB More: the full row for SEB Asset Management AB 69,630 $6.77M 0.03% 13F-HR Timeline HighVista Strategies LLC More: the full row for HighVista Strategies LLC 69,309 $6.74M 1.86% -50,931 13F-HR Timeline Edgestream Partners, L.P. More: the full row for Edgestream Partners, L.P. 69,262 $6.74M 0.22% new 13F-HR Timeline Trexquant Investment LP More: the full row for Trexquant Investment LP 68,609 $6.67M 0.05% +36,146 13F-HR Timeline Zurcher Kantonalbank (Zurich Cantonalba… More: the full row for Zurcher Kantonalbank (Zurich Cantonalbank) 68,018 $6.61M 0.01% +22,501 13F-HR Timeline Korea Investment CORP More: the full row for Korea Investment CORP 66,461 $6.46M 0.01% new 13F-HR Timeline Catalyst Funds Management Pty Ltd More: the full row for Catalyst Funds Management Pty Ltd 66,261 $6.44M 1.09% -157,308 13F-HR Timeline Quantinno Capital Management LP More: the full row for Quantinno Capital Management LP 63,360 $6.16M 0.01% +31,297 13F-HR Timeline NOMURA ASSET MANAGEMENT CO LTD group of 2 filers holding More: the full row for NOMURA ASSET MANAGEMENT CO LTD 63,279 $6.15M +63,279 Timeline Vestcor Inc More: the full row for Vestcor Inc 63,077 $6.13M 0.17% new 13F-HR Timeline GENERAL AMERICAN INVESTORS CO INC More: the full row for GENERAL AMERICAN INVESTORS CO INC 62,545 $6.08M 0.4% -1,500 13F-HR Timeline Handelsbanken Fonder AB More: the full row for Handelsbanken Fonder AB 61,775 $6.01M 0.02% +7,600 13F-HR Timeline SCHRODER INVESTMENT MANAGEMENT GROUP More: the full row for SCHRODER INVESTMENT MANAGEMENT GROUP 64,583 $5.99M <0.01% new 13F-HR Timeline KLP KAPITALFORVALTNING AS More: the full row for KLP KAPITALFORVALTNING AS 60,500 $5.88M 0.02% +30,496 13F-HR Timeline Mirae Asset Global Investments Co., Ltd. group of 2 filers holding More: the full row for Mirae Asset Global Investments Co., Ltd. 61,732 $5.86M +36,067 Timeline Quarry LP More: the full row for Quarry LP 59,263 $5.76M 1.16% new 13F-HR Timeline Erste Asset Management GmbH in group Erste Asset Management GmbH More: the full row for Erste Asset Management GmbH 59,400 $5.51M 0.05% +20,000 13F-HR Timeline Group Universal- Beteiligungs- und Serviceges… in group Universal- Beteiligungs- und … More: the full row for Universal- Beteiligungs- und Servicegesellschaft mbH 56,602 $5.5M 0.01% -9,025 13F-HR Timeline Group Asset Management One Co., Ltd. More: the full row for Asset Management One Co., Ltd. 55,816 $5.43M 0.02% new 13F-HR Timeline MOORE CAPITAL MANAGEMENT, LP More: the full row for MOORE CAPITAL MANAGEMENT, LP 55,600 $5.41M 0.2% 0 13F-HR Timeline SPHERA FUNDS MANAGEMENT LTD. in group SPHERA FUNDS MANAGEMENT LTD. More: the full row for SPHERA FUNDS MANAGEMENT LTD. 55,110 $5.36M 0.92% +2,610 13F-HR Timeline Group SG Americas Securities, LLC More: the full row for SG Americas Securities, LLC 53,426 $5.2M 0.01% +36,703 13F-HR Timeline STOREBRAND ASSET MANAGEMENT AS More: the full row for STOREBRAND ASSET MANAGEMENT AS 53,365 $5.19M 0.01% new 13F-HR Timeline ALLIANCEBERNSTEIN L.P. More: the full row for ALLIANCEBERNSTEIN L.P. 63,643 $5.07M <0.01% -2,880 13F-HR Timeline ORBIMED ADVISORS LLC in group ORBIMED ADVISORS LLC More: the full row for ORBIMED ADVISORS LLC 52,000 $5.06M 0.11% +26,100 13F-HR Timeline Group SUSQUEHANNA INTERNATIONAL GROUP, LLP in group SUSQUEHANNA INTERNATIONAL GRO… More: the full row for SUSQUEHANNA INTERNATIONAL GROUP, LLP 51,385 $5M 0.01% -131,836 13F-HR Timeline Group Informed Momentum Co LLC More: the full row for Informed Momentum Co LLC 50,122 $4.87M 0.56% -14,114 13F-HR Timeline Nantahala Capital Management, LLC in group Nantahala Capital Management,… More: the full row for Nantahala Capital Management, LLC 50,000 $4.86M 0.3% new 13F-HR Timeline Group State of New Jersey Common Pension Fund… in group State of New Jersey Common Pe… More: the full row for State of New Jersey Common Pension Fund D 49,551 $4.82M 0.02% -534 13F-HR Timeline Group PUBLIC EMPLOYEES RETIREMENT SYSTEM OF O… More: the full row for PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO 49,509 $4.81M 0.02% -2,656 13F-HR Timeline Creative Planning in group Creative Planning More: the full row for Creative Planning 49,392 $4.8M <0.01% +5,248 13F-HR Timeline Group DekaBank Deutsche Girozentrale More: the full row for DekaBank Deutsche Girozentrale 50,000 $4.71M 0.01% 0 13F-HR Timeline BESSEMER GROUP INC in group BESSEMER GROUP INC More: the full row for BESSEMER GROUP INC 48,062 $4.67M 0.01% -69,600 13F-HR Timeline Group VOYA INVESTMENT MANAGEMENT LLC in group VOYA INVESTMENT MANAGEMENT LLC More: the full row for VOYA INVESTMENT MANAGEMENT LLC 47,766 $4.65M <0.01% -12,471 13F-HR Timeline Group FJARDE AP-FONDEN /FOURTH SWEDISH NATION… More: the full row for FJARDE AP-FONDEN /FOURTH SWEDISH NATIONAL PENSION FUND 46,900 $4.56M 0.02% new 13F-HR Timeline Rafferty Asset Management, LLC More: the full row for Rafferty Asset Management, LLC 45,291 $4.4M 0.02% -29,407 13F-HR Timeline DANSKE BANK A/S More: the full row for DANSKE BANK A/S 44,900 $4.37M 0.01% +41,800 13F-HR Timeline Granahan Investment Management, LLC More: the full row for Granahan Investment Management, LLC 42,573 $4.14M 0.2% -56,621 13F-HR Timeline Jump Financial, LLC in group Jump Financial, LLC More: the full row for Jump Financial, LLC 42,330 $4.12M 0.06% new 13F-HR Timeline Group Resona Asset Management Co.,Ltd. in group Resona Asset Management Co.,L… More: the full row for Resona Asset Management Co.,Ltd. 41,680 $4.02M 0.02% new 13F-HR Timeline Group KVP Capital Advisors, LP More: the full row for KVP Capital Advisors, LP 40,200 $3.91M 2.92% +12,700 13F-HR Timeline Wedmont Private Capital More: the full row for Wedmont Private Capital 40,231 $3.89M 0.13% +175 13F-HR Timeline CANADA LIFE ASSURANCE Co in group CANADA LIFE ASSURANCE Co More: the full row for CANADA LIFE ASSURANCE Co 39,419 $3.84M 0.01% +22,870 13F-HR Timeline Group ARIZONA STATE RETIREMENT SYSTEM More: the full row for ARIZONA STATE RETIREMENT SYSTEM 39,396 $3.83M 0.02% +235 13F-HR Timeline Twin Securities, Inc. More: the full row for Twin Securities, Inc. 38,593 $3.75M 1.86% new 13F-HR Timeline Legato Capital Management LLC More: the full row for Legato Capital Management LLC 37,394 $3.64M 0.33% -11,357 13F-HR Timeline Athos Capital Ltd More: the full row for Athos Capital Ltd 36,900 $3.59M 1.11% new 13F-HR Timeline DNB Asset Management AS in group DNB Asset Management AS More: the full row for DNB Asset Management AS 36,187 $3.52M 0.01% new 13F-HR Timeline Group IEQ CAPITAL, LLC More: the full row for IEQ CAPITAL, LLC 36,113 $3.51M 0.02% -11,299 13F-HR Timeline China Universal Asset Management Co., L… More: the full row for China Universal Asset Management Co., Ltd. 35,167 $3.42M 0.26% +1,166 13F-HR Timeline Alberta Investment Management Corp More: the full row for Alberta Investment Management Corp 35,000 $3.4M 0.02% new 13F-HR Timeline WELLS FARGO & COMPANY/MN in group WELLS FARGO & COMPANY/MN More: the full row for WELLS FARGO & COMPANY/MN 34,241 $3.33M <0.01% +21,121 13F-HR/A Timeline Group