13F-HR filed by Frazier Life Sciences Management, L.P.
Frazier Life Sciences Management, L.P. filed this 13F-HR for the quarter ended 2026-03-31, filed 2026-05-15, with 38 holding rows worth $3,886,526,658.
- Accession
- 0001892134-26-000002
- Filer
- CIK 1892134
- Filed
- 2026-05-15
- Accepted by EDGAR
- acceptance time not in the bulk data set
- Ingested
- Source
- SEC quarterly data set
13F report for Q1 2026
A holdings report, 38 entries on the cover page, a total value of $3,886,526,658 stated on the cover page (in dollars after the unit check, H1), rows summing to $3,886,526,658 with VALUE read as dollars as filed, 13F file number 028-22504. The quarter's positions are built on this report. The resolved quarter.
The information table after summing rows of one CUSIP and put or call (H4), with the CUSIP and issuer name as filed. Values in dollars after the unit check (method).
| Issuer as filed | CUSIP | Class | Amount | Value | Value read as | Type |
|---|---|---|---|---|---|---|
| MIRUM PHARMACEUTICALS INC | 604749101 | COM | 7,679,684 | $709,449,208 | dollars as filed | |
| NEWAMSTERDAM PHARMA CO NV | N62509109 | COMMON STOCK | 16,943,774 | $542,370,206 | dollars as filed | |
| ERASCA INC COM | 29479A108 | Stock | 24,675,188 | $399,244,542 | dollars as filed | |
| BRIDGEBIO PHARMA INC | 10806X102 | COM | 3,448,139 | $256,058,802 | dollars as filed | |
| ARCUTIS BIOTHERAPEUTICS INC | 03969K108 | COM | 9,874,511 | $232,643,479 | dollars as filed | |
| MBX BIOSCIENCES INC COM | 55287L101 | Stock | 6,652,013 | $198,562,588 | dollars as filed | |
| PHATHOM PHARMACEUTICALS INC | 71722W107 | COMMON STOCK | 12,466,489 | $138,502,693 | dollars as filed | |
| MAZE THERAPEUTICS INC COM | 578784100 | Stock | 4,567,274 | $136,333,129 | dollars as filed | |
| KRYSTAL BIOTECH INC COM | 501147102 | Stock | 481,307 | $124,331,224 | dollars as filed | |
| TREVI THERAPEUTICS INC COM | 89532M101 | Stock | 9,939,547 | $118,578,796 | dollars as filed | |
| PALVELLA THERAPEUTICS INC | 697947109 | COMMON STOCK | 882,400 | $109,991,160 | dollars as filed | |
| KALVISTA PHARMACEUTICALS INC | 483497103 | COM | 4,961,108 | $99,867,104 | dollars as filed | |
| DISC MEDICINE INC COM | 254604101 | Stock | 1,354,852 | $86,629,237 | dollars as filed | |
| CYTOKINETICS INC | 23282W605 | COM NEW | 1,159,879 | $76,447,625 | dollars as filed | |
| REVOLUTION MEDICINES INC COM | 76155X100 | Stock | 675,686 | $65,710,464 | dollars as filed | |
| DYNE THERAPEUTICS INC COM | 26818M108 | Stock | 3,153,082 | $57,165,377 | dollars as filed | |
| SAVARA INC | 805111101 | COM | 9,720,852 | $53,075,852 | dollars as filed | |
| TARSUS PHARMACEUTICALS INC | 87650L103 | COMMON STOCK | 728,644 | $51,114,377 | dollars as filed | |
| VOR BIOPHARMA INC | 929033207 | COMMON STOCK | 2,543,939 | $45,383,872 | dollars as filed | |
| AGIOS PHARMACEUTICALS INC | 00847X104 | COM | 1,256,080 | $42,493,186 | dollars as filed | |
| BIOCRYST PHARMACEUTICALS INC COM | 09058V103 | Stock | 4,009,240 | $38,167,965 | dollars as filed | |
| ZAI LAB LTD ADR | 98887Q104 | ADR | 1,902,320 | $35,782,639 | dollars as filed | |
| AURA BIOSCIENCES INC | 05153U107 | COMMON STOCK | 5,100,000 | $34,119,000 | dollars as filed | |
| ACADIA PHARMACEUTICALS INC | 004225108 | COM | 1,438,198 | $32,014,287 | dollars as filed | |
| ASCENDIS PHARMA A/S DKK 1.0 AD | 04351P101 | SPONSORED ADR | 133,333 | $30,497,257 | dollars as filed | |
| LEXEO THERAPEUTICS INC | 52886X107 | COMMON STOCK | 4,424,725 | $25,397,922 | dollars as filed | |
| ALKERMES PLC | G01767105 | SHS | 700,647 | $24,774,878 | dollars as filed | |
| ACLARIS THERAPEUTICS INC COM | 00461U105 | Stock | 4,925,374 | $18,470,153 | dollars as filed | |
| MONTE ROSA THERAPEUTICS INC | 61225M102 | COM | 1,000,000 | $16,450,000 | dollars as filed | |
| IMMUNOCORE HLDGS PLC ADS | 45258D105 | ADR | 484,782 | $14,616,177 | dollars as filed | |
| MANNKIND CORP COM NEW | 56400P706 | Stock | 5,900,000 | $14,455,000 | dollars as filed | |
| Valneva SE ADR | 92025Y103 | COM | 2,291,666 | $14,322,913 | dollars as filed | |
| EVOLUS INC | 30052C107 | COM | 2,630,665 | $10,812,033 | dollars as filed | |
| NEWAMSTERDAM PHARMA CO NV-27 | N62509117 | WTS | 500,333 | $10,026,673 | dollars as filed | |
| ALLOGENE THERAPEUTICS INC | 019770106 | COM | 3,796,668 | $9,263,870 | dollars as filed | |
| AUTOLUS THERAPEUTICS PLC SPON | 05280R100 | COM | 4,447,910 | $6,138,116 | dollars as filed | |
| IBIO INC | 451033708 | CMN | 1,953,467 | $3,711,587 | dollars as filed | |
| XILIO THERAPEUTICS INC | 98422T209 | COM | 422,505 | $3,553,267 | dollars as filed |
Amendment chain
| Filing | Role | Filed | Accepted | Ingested |
|---|---|---|---|---|
| 13F-HR 0001892134-26-000002 | this filing | 2026-05-15 | acceptance time not in the bulk data set |