13F-HR filed by HighVista Strategies LLC
HighVista Strategies LLC filed this 13F-HR for the quarter ended 2026-03-31, filed 2026-05-15, with 156 holding rows worth $362,159,371.
- Accession
- 0001172661-26-002079
- Filer
- CIK 1335325
- Filed
- 2026-05-15
- Accepted by EDGAR
- acceptance time not in the bulk data set
- Ingested
- Source
- SEC quarterly data set
13F report for Q1 2026
A holdings report, 156 entries on the cover page, a total value of $362,159,371 stated on the cover page (in dollars after the unit check, H1), rows summing to $362,159,371 with VALUE read as dollars as filed, 13F file number 028-14212. The quarter's positions are built on this report. The resolved quarter.
Other managers
- included managerHighVista Private Capital Management LLC
The information table after summing rows of one CUSIP and put or call (H4), with the CUSIP and issuer name as filed. Values in dollars after the unit check (method).
| Issuer as filed | CUSIP | Class | Amount | Value | Value read as | Type |
|---|---|---|---|---|---|---|
| DB COMMODITY INDEX TRACKING | 46138B103 | ETF | 1,057,238 | $30,607,040 | dollars as filed | |
| ABIVAX SA- | 00370M103 | SPONSORED ADS | 113,254 | $12,610,833 | dollars as filed | |
| PRAXIS PRECISION MEDICINES I | 74006W207 | COM NEW | 26,323 | $8,481,008 | dollars as filed | |
| COGENT BIOSCIENCES INC | 19240Q201 | COM | 197,051 | $7,584,493 | dollars as filed | |
| SPYRE THERAPEUTICS INC | 00773J202 | COM NEW | 146,264 | $7,377,556 | dollars as filed | |
| VAXCYTE INC COM | 92243G108 | Stock | 124,647 | $7,243,237 | dollars as filed | |
| REVOLUTION MEDICINES INC COM | 76155X100 | Stock | 69,309 | $6,740,301 | dollars as filed | |
| TERNS PHARMACEUTICALS INC COM | 880881107 | Stock | 114,307 | $6,026,265 | dollars as filed | |
| STRUCTURE THERAPEUTICS INC COMP | 86366E106 | EQUITY | 123,909 | $5,972,414 | dollars as filed | |
| NUVALENT INC COM | 670703107 | Stock | 56,602 | $5,798,874 | dollars as filed | |
| IMMUNOVANT INC | 45258J102 | COM | 225,139 | $5,592,453 | dollars as filed | |
| SOLENO THERAPEUTICS INC | 834203309 | COM | 165,227 | $5,531,800 | dollars as filed | |
| TYRA BIOSCIENCES INC | 90240B106 | COMMON STOCK | 131,304 | $5,028,943 | dollars as filed | |
| AMYLYX PHARMACEUTICALS INC | 03237H101 | COM | 352,085 | $4,893,981 | dollars as filed | |
| Amazon.com, Inc | 023135106 | COM | 22,397 | $4,664,623 | dollars as filed | |
| LB PHARMACEUTICALS INC | 50180M108 | COMMON STOCK | 173,595 | $4,280,853 | dollars as filed | |
| RELAY THERAPEUTICS INC COM | 75943R102 | Stock | 421,881 | $4,197,716 | dollars as filed | |
| INSMED INC COM PAR $.01 | 457669307 | Stock | 24,316 | $3,976,152 | dollars as filed | |
| NVIDIA Corp | 67066G104 | COM | 22,420 | $3,910,048 | dollars as filed | |
| ORUKA THERAPEUTICS INC COM | 687604108 | Stock | 78,911 | $3,870,585 | dollars as filed | |
| CYTOKINETICS INC | 23282W605 | COM NEW | 58,643 | $3,865,160 | dollars as filed | |
| LIQUIDIA CORPORATION COM NEW | 53635D202 | Stock | 99,744 | $3,764,338 | dollars as filed | |
| OCULAR THERAPEUTIX INC | 67576A100 | COM | 441,573 | $3,740,123 | dollars as filed | |
| TARSUS PHARMACEUTICALS INC | 87650L103 | COMMON STOCK | 52,464 | $3,680,349 | dollars as filed | |
| BRIDGEBIO PHARMA INC | 10806X102 | COM | 49,560 | $3,680,325 | dollars as filed | |
| MOONLAKE IMMUNOTHERAPEUTICS CLASS A ORD | 61559X104 | Stock | 193,955 | $3,615,321 | dollars as filed | |
| ARGENX SE SPONSORED ADR | 04016X101 | ADR | 4,918 | $3,591,370 | dollars as filed | |
| PROTAGONIST THERAPEUTICS | 74366E102 | COM | 33,852 | $3,568,001 | dollars as filed | |
| PALISADE BIO INC | 696389402 | COMMON STOCK | 2,019,326 | $3,533,820 | dollars as filed | |
| DEFINIUM THERAPEUTICS INC | 24477V105 | COM SHS | 185,856 | $3,512,679 | dollars as filed | |
| NURIX THERAPEUTICS INC | 67080M103 | COMMON STOCK | 226,546 | $3,511,464 | dollars as filed | |
| AXSOME THERAPEUTICS INC. COM | 05464T104 | Stock | 20,437 | $3,454,262 | dollars as filed | |
| INVENTIVA SA | 46124U107 | ADS | 615,666 | $3,416,946 | dollars as filed | |
| DYNE THERAPEUTICS INC COM | 26818M108 | Stock | 182,929 | $3,316,503 | dollars as filed | |
| APOGEE THERAPEUTICS INC COM | 03770N101 | Stock | 35,761 | $3,010,003 | dollars as filed | |
| GH RESEARCH PLC ORDINARY SHARES | G3855L106 | Stock | 213,212 | $2,997,761 | dollars as filed | |
| DIANTHUS THERAPEUTICS INC | 252828108 | COM | 35,587 | $2,986,461 | dollars as filed | |
| MAZE THERAPEUTICS INC COM | 578784100 | Stock | 99,850 | $2,980,523 | dollars as filed | |
| ERASCA INC COM | 29479A108 | Stock | 181,069 | $2,929,696 | dollars as filed | |
| EDGEWISE THERAPEUTICS INC | 28036F105 | COM | 91,931 | $2,895,827 | dollars as filed | |
| ENLIVEN THERAPEUTICS INC COM | 29337E102 | Stock | 73,102 | $2,865,598 | dollars as filed | |
| XENON PHARMACEUTICALS INC COM | 98420N105 | Stock | 49,050 | $2,852,257 | dollars as filed | |
| CELLDEX THERAPEUTICS INC NEW | 15117B202 | COM NEW | 89,397 | $2,835,673 | dollars as filed | |
| VERA THERAPEUTICS INC | 92337R101 | COMMON STOCK | 69,241 | $2,785,566 | dollars as filed | |
| PHARVARIS NV | N69605108 | COMMON STOCK | 97,866 | $2,764,715 | dollars as filed | |
| VIRIDIAN THERAPEUTICS INC | 92790C104 | COM | 134,229 | $2,625,519 | dollars as filed | |
| ALKERMES PLC | G01767105 | SHS | 73,189 | $2,587,963 | dollars as filed | |
| ALUMIS INC | 022307102 | COM | 112,929 | $2,487,826 | dollars as filed | |
| Microsoft Corp | 594918104 | COM | 6,457 | $2,390,188 | dollars as filed | |
| EYEPOINT INC COM NEW | 30233G209 | Stock | 183,037 | $2,359,347 | dollars as filed | |
| LUMENTUM HLDGS INC COM | 55024U109 | Stock | 3,117 | $2,190,503 | dollars as filed | |
| TANGO THERAPEUTICS INC | 87583X109 | COM | 104,193 | $2,179,717 | dollars as filed | |
| Visa Inc | 92826C839 | COM | 7,141 | $2,158,295 | dollars as filed | |
| GUARDANT HEALTH INC COM | 40131M109 | Stock | 23,357 | $2,157,486 | dollars as filed | |
| HEWLETT PACKARD ENTERPRISE CO COM | 42824C109 | Stock | 89,981 | $2,142,448 | dollars as filed | |
| ASSEMBLY BIOSCIENCES INC | 045396207 | COMMON STOCK | 74,735 | $2,073,896 | dollars as filed | |
| CIENA CORP COM NEW | 171779309 | Stock | 5,285 | $2,051,796 | dollars as filed | |
| JAZZ PHARMACEUTICALS PLC SHS USD | G50871105 | Stock | 10,838 | $2,048,924 | dollars as filed | |
| STOKE THERAPEUTICS INC | 86150R107 | COM | 62,617 | $2,038,809 | dollars as filed | |
| COMPASS PATHWAYS PLC | 20451W101 | SPONSORED ADS | 364,360 | $2,014,911 | dollars as filed | |
| FLOWSERVE CORP | 34354P105 | COM | 24,958 | $1,834,663 | dollars as filed | |
| IMMUNOCORE HLDGS PLC ADS | 45258D105 | ADR | 58,697 | $1,769,715 | dollars as filed | |
| OLEMA PHARMACEUTICALS INC | 68062P106 | COM | 117,601 | $1,753,431 | dollars as filed | |
| NCR ATLEOS CORPORATION | 63001N106 | COM SHS | 40,100 | $1,747,558 | dollars as filed | |
| XPO INC COM | 983793100 | Stock | 8,923 | $1,735,970 | dollars as filed | |
| ON SEMICONDUCTOR CORP COM | 682189105 | Stock | 28,000 | $1,733,760 | dollars as filed | |
| Broadcom Inc. | 11135F101 | COM | 5,599 | $1,732,946 | dollars as filed | |
| KODIAK SCIENCES INC | 50015M109 | COM | 43,569 | $1,660,851 | dollars as filed | |
| CONSTELLATION ENERGY CORP COM | 21037T109 | Stock | 5,752 | $1,606,247 | dollars as filed | |
| CLEAN HARBORS INC COM | 184496107 | Stock | 5,543 | $1,589,344 | dollars as filed | |
| Alphabet Inc. Reg. Shares C | 02079K107 | COM | 5,477 | $1,571,132 | dollars as filed | |
| Salesforce.com, Inc | 79466L302 | COM | 8,313 | $1,551,787 | dollars as filed | |
| CORE SCIENTIFIC INC NEW | 21874A106 | COM | 103,412 | $1,547,044 | dollars as filed | |
| ENTERGY CORP NEW COM | 29364G103 | Stock | 13,528 | $1,520,006 | dollars as filed | |
| CELCUITY INC | 15102K100 | COM | 13,105 | $1,495,805 | dollars as filed | |
| XOMA ROYALTY CORPORATION | 98419J206 | COMMON STOCK | 46,814 | $1,468,555 | dollars as filed | |
| AVANTOR INC COM | 05352A100 | Stock | 186,500 | $1,462,160 | dollars as filed | |
| MasterCard, Inc | 57636Q104 | COM | 2,924 | $1,461,006 | dollars as filed | |
| RHYTHM PHARMACEUTICALS INC | 76243J105 | COM | 16,796 | $1,460,748 | dollars as filed | |
| KBR INC COM | 48242W106 | Stock | 39,406 | $1,452,505 | dollars as filed | |
| RBC BEARINGS INC COM | 75524B104 | Stock | 2,663 | $1,446,328 | dollars as filed | |
| MIRUM PHARMACEUTICALS INC | 604749101 | COM | 15,563 | $1,437,710 | dollars as filed | |
| UNITY SOFTWARE INC COM | 91332U101 | Stock | 62,763 | $1,377,020 | dollars as filed | |
| SAVARA INC | 805111101 | COM | 250,999 | $1,370,455 | dollars as filed | |
| MADRIGAL PHARMACEUTICALS INC COM | 558868105 | Stock | 2,598 | $1,359,975 | dollars as filed | |
| CYTOMX THERAPEUTICS INC | 23284F105 | COMMON STOCK | 288,057 | $1,353,868 | dollars as filed | |
| CG ONCOLOGY INC | 156944100 | COMMON STOCK | 19,914 | $1,347,779 | dollars as filed | |
| TRANSDIGM GROUP INC COM | 893641100 | Stock | 1,145 | $1,327,009 | dollars as filed | |
| ASCENDIS PHARMA A/S DKK 1.0 AD | 04351P101 | SPONSORED ADR | 5,781 | $1,322,288 | dollars as filed | |
| KNIGHT-SWIFT TRANSN HLDGS IN | 499049104 | CL A | 22,900 | $1,318,582 | dollars as filed | |
| ROCKET COS INC | 77311W101 | COM CL A | 92,430 | $1,317,128 | dollars as filed | |
| Intuit Inc. | 461202103 | COM | 3,003 | $1,298,437 | dollars as filed | |
| Micron Technology,Inc. | 595112103 | COM | 3,800 | $1,283,792 | dollars as filed | |
| BELITE BIO INC | 07782B104 | CMN | 8,033 | $1,280,781 | dollars as filed | |
| MINERALYS THERAPEUTICS INC | 603170101 | COM | 46,778 | $1,267,216 | dollars as filed | |
| JAMES HARDIE INDS PLC ORD SHS | G4253H101 | Stock | 65,598 | $1,242,426 | dollars as filed | |
| AMPHENOL CORP NEW | 032095101 | COM | 9,781 | $1,235,829 | dollars as filed | |
| Booking Holdings Inc. | 09857L108 | COM | 283 | $1,191,521 | dollars as filed | |
| KILROY REALTY CORP COM | 49427F108 | REIT | 41,997 | $1,184,736 | dollars as filed | |
| MASTEC INC COM | 576323109 | Stock | 3,627 | $1,166,951 | dollars as filed | |
| EQT CORP COM | 26884L109 | Stock | 18,290 | $1,163,976 | dollars as filed | |
| SEAGATE TECHNOLOGY HLDNGS | G7997R103 | ORD SHS | 2,900 | $1,136,104 | dollars as filed | |
| PETROLEO BRASILEIRO S A | 71654V101 | SP ADR NON VTG | 59,400 | $1,113,750 | dollars as filed | |
| WESTERN DIGITAL CORP | 958102105 | COM | 4,100 | $1,109,009 | dollars as filed | |
| FERGUSON ENTERPRISES INC COMMON STOCK NEW | 31488V107 | Stock | 4,673 | $1,090,024 | dollars as filed | |
| API GROUP CORP COM STK | 00187Y100 | Stock | 26,658 | $1,080,182 | dollars as filed | |
| TRAVERE THERAPEUTICS INC | 89422G107 | COM | 36,325 | $1,079,216 | dollars as filed | |
| WORKDAY INC CL A | 98138H101 | Stock | 8,286 | $1,076,517 | dollars as filed | |
| PTC INC COM | 69370C100 | Stock | 7,474 | $1,064,970 | dollars as filed | |
| GE Vernova Inc. | 36828A101 | COM | 1,218 | $1,063,192 | dollars as filed | |
| NEKTAR THERAPEUTICS | 640268306 | COMMON STOCK | 14,555 | $1,047,232 | dollars as filed | |
| ARGAN INC | 04010E109 | COM | 1,896 | $1,032,656 | dollars as filed | |
| NextEra Energy,Inc. | 65339F101 | COM | 11,085 | $1,029,575 | dollars as filed | |
| DOORDASH INC CL A | 25809K105 | Stock | 6,710 | $1,007,507 | dollars as filed | |
| XCELENERGY INC | 98389B100 | COM | 12,558 | $997,608 | dollars as filed | |
| META PLATFORMS INC CL A | 30303M102 | COM | 1,742 | $996,651 | dollars as filed | |
| TALEN ENERGY CORP COM | 87422Q109 | Stock | 3,118 | $995,359 | dollars as filed | |
| AMRIZE LTD SHS | H2927K103 | Stock | 17,068 | $956,149 | dollars as filed | |
| REDDIT INC CL A | 75734B100 | Stock | 6,900 | $929,085 | dollars as filed | |
| UNITED THERAPEUTICS CORP DEL COM | 91307C102 | Stock | 1,514 | $897,771 | dollars as filed | |
| 3M CO COM | 88579Y101 | Stock | 6,150 | $893,165 | dollars as filed | |
| Union Pacific Corporation | 907818108 | COM | 3,658 | $887,504 | dollars as filed | |
| AVALO THERAPEUTICS INC | 05338F306 | COMMON STOCK | 58,622 | $875,226 | dollars as filed | |
| COUPANG INC | 22266T109 | CL A | 46,036 | $869,160 | dollars as filed | |
| CLEVELAND-CLIFFS INC NEW COM | 185899101 | Stock | 102,474 | $865,905 | dollars as filed | |
| ZYMEWORKS INC | 98985Y108 | COM | 34,085 | $853,488 | dollars as filed | |
| EVERPURE INC CL A | 74624M102 | Stock | 14,009 | $827,091 | dollars as filed | |
| BANCO BRADESCO S A | 059460303 | SP ADR PFD NEW | 208,264 | $760,164 | dollars as filed | |
| CORPORACION AMER ARPTS S A | L1995B107 | COM | 29,745 | $752,251 | dollars as filed | |
| MERCADOLIBREINC | 58733R102 | STOK | 435 | $752,124 | dollars as filed | |
| PALVELLA THERAPEUTICS INC | 697947109 | COMMON STOCK | 5,903 | $735,809 | dollars as filed | |
| ICICI BANK LIMITED ADR | 45104G104 | ADR | 27,884 | $722,195 | dollars as filed | |
| NU HLDGS LTD | G6683N103 | ORD SHS CL A | 49,570 | $712,321 | dollars as filed | |
| PDD HOLDINGS INC SPONSORED ADS | 722304102 | ADR | 6,900 | $705,042 | dollars as filed | |
| BRIDGEBIO ONCOLOGY THERAPEUT | 107924102 | COM NEW | 78,187 | $699,774 | dollars as filed | |
| NEW ORIENTAL ED & TECHNOLOGY SPON ADR | 647581206 | ADR | 12,317 | $697,512 | dollars as filed | |
| JANUX THERAPEUTICS INC | 47103J105 | COM | 49,383 | $686,424 | dollars as filed | |
| RLX TECHNOLOGY INC | 74969N103 | SPONSORED ADS | 311,700 | $685,740 | dollars as filed | |
| HDFC BANK LTD SPONSORED ADS | 40415F101 | ADR | 26,127 | $650,039 | dollars as filed | |
| NEWAMSTERDAM PHARMA CO NV | N62509109 | COMMON STOCK | 20,067 | $642,344 | dollars as filed | |
| FULL TRUCK ALLIANCE CO LTD SPONSORED ADS | 35969L108 | ADR | 77,191 | $640,685 | dollars as filed | |
| XENCOR INC | 98401F105 | COMMON STOCK | 53,045 | $639,723 | dollars as filed | |
| TREVI THERAPEUTICS INC COM | 89532M101 | Stock | 53,525 | $638,553 | dollars as filed | |
| PENNYMAC FINL SVCS INC NEW | 70932M107 | COM | 7,306 | $638,544 | dollars as filed | |
| RXO, Inc. | 74982T103 | Common Stock, $0.01 par value | 43,038 | $629,216 | dollars as filed | |
| SEA LTD | 81141R100 | SPONSORD ADS | 7,450 | $616,935 | dollars as filed | |
| NOKIA CORP | 654902204 | SPONSORED ADR | 70,824 | $569,425 | dollars as filed | |
| QXO INC COM NEW | 82846H405 | Stock | 26,320 | $511,134 | dollars as filed | |
| UROGEN PHARMA LTD | M96088105 | COMMON STOCK | 26,510 | $476,650 | dollars as filed | |
| KRYSTAL BIOTECH INC COM | 501147102 | Stock | 1,824 | $471,175 | dollars as filed | |
| JD.COM INC SPON ADS CL A | 47215P106 | ADR | 13,463 | $398,101 | dollars as filed | |
| MBX BIOSCIENCES INC COM | 55287L101 | Stock | 11,472 | $342,439 | dollars as filed | |
| KYMERA THERAPEUTICS INC | 501575104 | COM | 3,785 | $315,253 | dollars as filed | |
| KANZHUN LIMITED | 48553T106 | SPONSORED ADS | 21,298 | $285,180 | dollars as filed | |
| TRIP COM GROUP LTD ADS | 89677Q107 | ADR | 5,484 | $273,049 | dollars as filed | |
| CENTESSA PHARMACEUTICALS PLC | 152309100 | SPONSORED ADS | 5,964 | $236,890 | dollars as filed |
Amendment chain
| Filing | Role | Filed | Accepted | Ingested |
|---|---|---|---|---|
| 13F-HR 0001172661-26-002079 | this filing | 2026-05-15 | acceptance time not in the bulk data set |