13F-HR filed by DAFNA Capital Management LLC
DAFNA Capital Management LLC filed this 13F-HR for the quarter ended 2026-03-31, filed 2026-05-15, with 83 holding rows worth $439,591,894.
- Accession
- 0001389933-26-000004
- Filer
- CIK 1389933
- Filed
- 2026-05-15
- Accepted by EDGAR
- acceptance time not in the bulk data set
- Ingested
- Source
- SEC quarterly data set
13F report for Q1 2026
A holdings report, 83 entries on the cover page, a total value of $439,591,894 stated on the cover page (in dollars after the unit check, H1), rows summing to $439,591,894 with VALUE read as dollars as filed, 13F file number 028-12327. The quarter's positions are built on this report. The resolved quarter.
Other managers
- included managerFischel Nathan028-12328
The information table after summing rows of one CUSIP and put or call (H4), with the CUSIP and issuer name as filed. Values in dollars after the unit check (method).
| Issuer as filed | CUSIP | Class | Amount | Value | Value read as | Type |
|---|---|---|---|---|---|---|
| REVOLUTION MEDICINES INC COM | 76155X100 | Stock | 580,678 | $56,470,936 | dollars as filed | |
| SPDR SER TR | 78464A870 | S&P BIOTECH | 318,505 | $40,682,644 | dollars as filed | |
| STEREOTAXIS INC | 85916J409 | COMMON STOCK | 13,680,554 | $25,172,219 | dollars as filed | |
| Day One Biopharmaceuticals Inc | 23954D109 | Common Stock | 978,463 | $20,978,247 | dollars as filed | |
| ATRICURE INC | 04963C209 | COM | 597,431 | $17,044,706 | dollars as filed | |
| IDEAYA BIOSCIENCES INC COM | 45166A102 | Stock | 476,740 | $15,884,977 | dollars as filed | |
| XENON PHARMACEUTICALS INC COM | 98420N105 | Stock | 250,772 | $14,582,392 | dollars as filed | |
| CYTOKINETICS INC | 23282W605 | COM NEW | 217,497 | $14,335,227 | dollars as filed | |
| COMPASS PATHWAYS PLC | 20451W101 | SPONSORED ADS | 2,418,882 | $13,376,417 | dollars as filed | |
| NEKTAR THERAPEUTICS | 640268306 | COMMON STOCK | 165,178 | $11,884,557 | dollars as filed | |
| ISHARES TR | 464287556 | ISHARES BIOTECH | 62,095 | $10,484,741 | dollars as filed | |
| ARCUS BIOSCIENCES INC | 03969F109 | COM | 443,829 | $9,586,706 | dollars as filed | |
| NEUROCRINE BIOSCIENCES INC | 64125C109 | COM | 70,615 | $9,302,820 | dollars as filed | |
| LARIMAR THERAPEUTICS INC | 517125100 | COM | 2,029,164 | $9,131,238 | dollars as filed | |
| BICARA THERAPEUTICS INC | 055477103 | COM | 421,733 | $8,388,269 | dollars as filed | |
| AXOGEN INC | 05463X106 | COM | 249,960 | $8,281,175 | dollars as filed | |
| BIOHAVEN LTD | G1110E107 | COM | 845,735 | $7,154,918 | dollars as filed | |
| TANDEM DIABETES CARE INC | 875372203 | COM NEW | 355,208 | $6,809,337 | dollars as filed | |
| DENALI THERAPEUTICS INC COM | 24823R105 | Stock | 318,500 | $6,115,200 | dollars as filed | |
| Ascendis Pharma A/S | 04351PAD3 | Convertible bond | 4,000,000 | $5,916,500 | dollars as filed | principal |
| CENTURY THERAPEUTICS INC | 15673T100 | COM | 2,434,353 | $5,501,638 | dollars as filed | |
| DEXCOM INC COM | 252131107 | Stock | 86,279 | $5,418,321 | dollars as filed | |
| KALVISTA PHARMACEUTICALS INC | 483497103 | COM | 267,402 | $5,382,802 | dollars as filed | |
| ASCENDIS PHARMA A/S DKK 1.0 AD | 04351P101 | SPONSORED ADR | 23,177 | $5,301,275 | dollars as filed | |
| MBX BIOSCIENCES INC COM | 55287L101 | Stock | 175,465 | $5,237,630 | dollars as filed | |
| INOGEN INC | 45780L104 | COM | 845,179 | $5,223,206 | dollars as filed | |
| SYNDAX PHARMACEUTICALS INC | 87164F105 | COM | 217,355 | $5,077,413 | dollars as filed | |
| ALKERMES PLC | G01767105 | SHS | 139,482 | $4,932,084 | dollars as filed | |
| STOKE THERAPEUTICS INC | 86150R107 | COM | 130,875 | $4,261,290 | dollars as filed | |
| BIOCRYST PHARMACEUTICALS INC COM | 09058V103 | Stock | 430,248 | $4,095,961 | dollars as filed | |
| LAKEFRONT BIOTHERAPEUTICS NV | 36315X101 | SPON ADR | 130,175 | $3,905,250 | dollars as filed | |
| IMMUNOVANT INC | 45258J102 | COM | 150,524 | $3,739,016 | dollars as filed | |
| EDGEWISE THERAPEUTICS INC | 28036F105 | COM | 112,236 | $3,535,434 | dollars as filed | |
| MAPLIGHT THERAPEUTICS INC | 56565P103 | COMMON STOCK | 171,006 | $3,476,552 | dollars as filed | |
| ALLOGENE THERAPEUTICS INC | 019770106 | COM | 1,370,118 | $3,343,088 | dollars as filed | |
| PROCEPT BIOROBOTICS CORP COM | 74276L105 | Stock | 120,000 | $3,001,200 | dollars as filed | |
| ALIGN TECHNOLOGY INC COM | 016255101 | Stock | 15,000 | $2,571,450 | dollars as filed | |
| PROQR THERAPEUTICS NV | N71542109 | SHS EURO | 1,567,561 | $2,539,449 | dollars as filed | |
| CYBIN INC | 23256X407 | COM NEW | 498,361 | $2,392,133 | dollars as filed | |
| RAPPORT THERAPEUTICS INC COM | 75383L102 | Stock | 75,000 | $2,346,750 | dollars as filed | |
| INSULET CORP COM | 45784P101 | Stock | 10,870 | $2,280,961 | dollars as filed | |
| STRUCTURE THERAPEUTICS INC COMP | 86366E106 | EQUITY | 46,500 | $2,241,300 | dollars as filed | |
| IMMATICS N.V | N44445109 | SHS | 225,860 | $2,222,462 | dollars as filed | |
| CELLDEX THERAPEUTICS INC NEW | 15117B202 | COM NEW | 68,518 | $2,173,391 | dollars as filed | |
| LEXEO THERAPEUTICS INC | 52886X107 | COMMON STOCK | 377,059 | $2,164,319 | dollars as filed | |
| ALECTOR INC | 014442107 | COMMON STOCK | 908,351 | $1,952,955 | dollars as filed | |
| VIKING THERAPEUTICS INC | 92686J106 | COM | 59,516 | $1,936,651 | dollars as filed | |
| KURA ONCOLOGY INC COM | 50127T109 | Stock | 235,868 | $1,917,607 | dollars as filed | |
| PROFOUND MED CORP | 74319B502 | COM NEW | 263,005 | $1,704,272 | dollars as filed | |
| FULCRUM THERAPEUTICS INC | 359616109 | COMMON STOCK | 205,000 | $1,572,350 | dollars as filed | |
| AQUESTIVE THERAPEUTICS INC COM | 03843E104 | Stock | 368,415 | $1,528,922 | dollars as filed | |
| MEDIWOUND LTD | M68830112 | COMMON STOCK | 94,405 | $1,520,865 | dollars as filed | |
| ORTHOPEDIATRICS CORP | 68752L100 | COMMON STOCK | 95,659 | $1,518,108 | dollars as filed | |
| ULTRAGENYX PHARMACEUTICAL IN | 90400D108 | COM | 61,100 | $1,280,045 | dollars as filed | |
| ENGENE HOLDINGS INC | 29286M105 | COM | 187,353 | $1,275,874 | dollars as filed | |
| NEUROGENE INC | 64135M105 | COMMON STOCK | 56,635 | $1,141,762 | dollars as filed | |
| ARS PHARMACEUTICALS INC | 82835W108 | COM | 139,285 | $1,118,459 | dollars as filed | |
| CYTOMX THERAPEUTICS INC | 23284F105 | COMMON STOCK | 230,000 | $1,081,000 | dollars as filed | |
| MAZE THERAPEUTICS INC COM | 578784100 | Stock | 35,000 | $1,044,750 | dollars as filed | |
| MINERALYS THERAPEUTICS INC | 603170101 | COM | 38,490 | $1,042,694 | dollars as filed | |
| SCYNEXIS INC | 811292200 | COM NEW | 1,086,956 | $996,630 | dollars as filed | |
| ORIC PHARMACEUTICALS INC | 68622P109 | COM | 98,724 | $945,460 | dollars as filed | |
| INSPIRE MED SYS INC COM | 457730109 | Stock | 18,200 | $938,756 | dollars as filed | |
| POLYPID LTD | M8001Q126 | COM | 207,900 | $910,602 | dollars as filed | |
| TELA BIO INC | 872381108 | COM | 1,441,029 | $893,438 | dollars as filed | |
| ZENAS BIOPHARMA INC COM | 98937L105 | Stock | 42,500 | $830,875 | dollars as filed | |
| VERRICA PHARMACEUTICALS INC | 92511W207 | COM SHS | 153,712 | $813,136 | dollars as filed | |
| FATE THERAPEUTICS INC | 31189P102 | COM | 550,000 | $660,000 | dollars as filed | |
| ANNEXON INC | 03589W102 | COM | 117,812 | $652,678 | dollars as filed | |
| ACCURAY INC DEL | 004397105 | COM | 1,680,508 | $652,205 | dollars as filed | |
| NEWAMSTERDAM PHARMA CO NV | N62509109 | COMMON STOCK | 20,000 | $640,200 | dollars as filed | |
| ADICET BIO INC | 007002207 | COM NEW | 93,812 | $638,860 | dollars as filed | |
| BIONTECH SE SPONSORED ADS | 09075V102 | ADR | 7,000 | $622,160 | dollars as filed | |
| PLIANT THERAPEUTICS INC | 729139105 | COM | 487,000 | $613,620 | dollars as filed | |
| COMPUGEN LTD | M25722105 | ORD | 257,783 | $549,078 | dollars as filed | |
| ORCHESTRA BIOMED HOLDINGS IN | 68572M106 | COMMON STOCK | 126,841 | $539,074 | dollars as filed | |
| FOGHORN THERAPEUTICS INC | 344174107 | COMMON STOCK | 111,859 | $534,686 | dollars as filed | |
| IBIO INC | 451033708 | CMN | 193,638 | $367,912 | dollars as filed | |
| BICYCLE THERAPEUTICS PLC-ADR | 088786108 | SPONSORED ADS | 64,492 | $299,243 | dollars as filed | |
| ADC THERAPEUTICS SA | H0036K147 | COMMON STOCK | 72,081 | $270,304 | dollars as filed | |
| KARYOPHARM THERAPEUTICS INC | 48576U205 | COMMON STOCK | 45,800 | $255,106 | dollars as filed | |
| AUTOLUS THERAPEUTICS PLC SPON | 05280R100 | COM | 179,316 | $247,456 | dollars as filed | |
| NEUMORA THERAPEUTICS INC. | 640979100 | COM | 70,000 | $136,500 | dollars as filed |
Amendment chain
| Filing | Role | Filed | Accepted | Ingested |
|---|---|---|---|---|
| 13F-HR 0001389933-26-000004 | this filing | 2026-05-15 | acceptance time not in the bulk data set |