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Disclosery

MLYS MINERALYS THERAPEUTICS INC

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COM (common), issuer CIK 1933414

220 managers (224 13F filers) reported a position in MLYS shares at 2025-12-31, 88,386,859 shares in all. 46 filers opened a position and 20 filers sold out during the quarter.

Managers
220
13F filers
224
New
46
Added
82
Reduced
72
Sold out
20
Shares held by filers
88,386,859

Shares held by filers adds up every 13F filer's report, so a share reported by a parent and by its subsidiary counts twice (H9). Managers counts each filer group once.

13D and 13G filers

No 13D or 13G on this security in the data. Structured 13D/G data starts 2024-12-18.

Insider trades

No Form 4 transaction on this security in the data.

13F holders, Q4 2025

Filers in the available 13F reports with a share position at 2025-12-31, filer groups collapsed to one row (method), largest first. Options and principal amounts are left out. A group row states no % of portfolio, since each member reports its own portfolio: the members' percents are listed under it. A value about 1,000 times or 1/1,000 of the price other filers imply is shown as filed but neither ranks the row nor enters a sum.

HolderSharesValue% of portfolioChangeSource
Catalys Pacific, LLC7,903,838$287M92.37%-1,000,00013F-HRTimeline
RA CAPITAL MANAGEMENT, L.P.in group RA CAPITAL MANAGEMENT, L.P.7,323,750$266M2.72%013F-HRTimelineGroup
SAMSARA BIOCAPITAL, LLC5,871,018$213M21.98%-392,13313F-HRTimeline
FMR LLCin group FMR LLC5,057,509$184M0.01%+2,986,25413F-HRTimelineGroup
BlackRock, Inc.in group BlackRock, Inc.4,327,678$157M<0.01%+656,06413F-HRTimelineGroup
VANGUARD GROUP INCin group VANGUARD GROUP INC3,352,880$122M<0.01%+333,88113F-HRTimelineGroup
STATE STREET CORPin group STATE STREET CORP3,184,999$116M<0.01%+1,881,97613F-HRTimelineGroup
Caligan Partners LP2,772,654$101M9.21%013F-HRTimeline
FRANKLIN RESOURCES INCin group Franklin Resources1,788,747$64.9M0.02%-21,02113F-HRTimelineGroup
Laurion Capital Management LP1,713,485$62.2M4.24%-6,96013F-HR/ATimeline
Holocene Advisors, LP1,602,035$58.1M0.12%+396,65813F-HRTimeline
ANDERA PARTNERS1,591,917$57.8M32.71%13F-HRTimeline
SR One Capital Management, LP1,563,966$56.8M8.03%-549,96713F-HRTimeline
MONTANOVA CAPITAL, LLC1,538,662$55.8M1.39%-593,47113F-HRTimeline
GOLDMAN SACHS GROUP INCin group GOLDMAN SACHS GROUP INC1,450,933$52.7M0.01%+739,27213F-HR/ATimelineGroup
Polar Capital Holdings Plcin group Polar Capital Holdings Plc1,401,141$50.8M0.23%+342,36513F-HRTimelineGroup
PRICE T ROWE ASSOCIATES INC /MD/1,325,120$48.1M0.01%+1,303,73713F-HRTimeline
SAMLYN CAPITAL, LLCin group SAMLYN CAPITAL, LLC1,304,932$47.4M0.76%new13F-HRTimelineGroup
JENNISON ASSOCIATES LLC1,258,653$45.7M0.03%+882,30713F-HRTimeline
GEODE CAPITAL MANAGEMENT, LLCin group GEODE CAPITAL MANAGEMENT, LLC1,257,582$45.6M<0.01%+134,17113F-HRTimelineGroup
JANUS HENDERSON GROUP PLCin group Janus Henderson1,213,265$44M0.02%+1,193,41713F-HRTimelineGroup
Point72 Asset Management, L.P.in group Point72 Asset Management, L.P.1,207,220$43.8M0.07%-592,40813F-HRTimelineGroup
Capital International Investorsin group Capital International Investo…1,163,290$42.2M0.01%-1,230,10613F-HRTimelineGroup
D. E. Shaw & Co., Inc.in group D. E. Shaw & Co., Inc.1,150,670$41.8M0.03%+539,74713F-HRTimelineGroup
BOOTHBAY FUND MANAGEMENT, LLC992,082$36M0.92%+49,45613F-HRTimeline
BANK OF AMERICA CORP /DE/in group BANK OF AMERICA CORP /DE/987,280$35.8M<0.01%+219,01513F-HRTimelineGroup
ORBIMED ADVISORS LLCin group ORBIMED ADVISORS LLC980,400$35.6M0.73%-489,09413F-HRTimelineGroup
TWO SIGMA INVESTMENTS, LPgroup of 2 filers holding964,103$35MnewTimeline
ALLIANCEBERNSTEIN L.P.922,516$33.5M0.01%+40,10113F-HRTimeline
AMERICAN CENTURY COMPANIES INCin group AMERICAN CENTURY COMPANIES INC908,093$33M0.02%+28,41113F-HRTimelineGroup
Pictet Asset Management Holding SAin group Pictet Asset Management Holdi…852,883$31M0.03%-76,28613F-HRTimelineGroup
FARALLON CAPITAL MANAGEMENT, L.L.C.823,296$29.9M0.16%-849,75713F-HRTimelineThe filing omitted confidential holdings, a later amendment may add them.
WELLINGTON MANAGEMENT GROUP LLPin group WELLINGTON MANAGEMENT GROUP L…784,267$28.5M<0.01%+82213F-HRTimelineGroup
Integral Health Asset Management, LLC750,000$27.2M1.38%-750,00013F-HRTimeline
Affinity Asset Advisors, LLC730,000$26.5M1.9%-20,00013F-HRTimeline
Siren, L.L.C.in group Siren, L.L.C.699,999$25.4M0.76%new13F-HRTimelineGroup
Candriam S.C.A.678,387$24.6M0.12%+110,60613F-HR/ATimeline
ARMISTICE CAPITAL, LLC676,035$24.5M0.6%+168,38513F-HRTimeline
Nationale-Nederlanden Powszechne Towarz…659,076$23.9M2.12%new13F-HRTimeline
MORGAN STANLEYin group MORGAN STANLEY639,507$23.2M<0.01%-737,49113F-HR/ATimelineGroup
Qube Research & Technologies Ltd496,549$18M0.03%+316,12313F-HRTimeline
CHARLES SCHWAB INVESTMENT MANAGEMENT INCin group Charles Schwab Trust Co461,300$16.7M<0.01%+52,11313F-HRTimelineGroup
SPHERA FUNDS MANAGEMENT LTD.in group SPHERA FUNDS MANAGEMENT LTD.449,003$16.3M3.41%+229,09313F-HRTimelineGroup
Rock Springs Capital Management LP427,596$15.5M0.8%+19,28313F-HRTimeline
Parkman Healthcare Partners LLC410,249$14.9M1.42%-45,27413F-HRTimeline
CITADEL ADVISORS LLCin group CITADEL ADVISORS LLC399,919$14.5M0.01%-1,667,30813F-HRTimelineGroup
TimesSquare Capital Management, LLC380,100$13.8M0.21%new13F-HRTimeline
22NW, LP358,325$13M6.06%013F-HRTimeline
Catalio Capital Management, LP331,849$12M2.13%new13F-HR/ATimeline
RENAISSANCE TECHNOLOGIES LLC322,100$11.7M0.02%+274,70013F-HRTimeline
LORD, ABBETT & CO. LLC312,396$11.3M0.03%new13F-HRTimeline
NORTHERN TRUST CORPin group NORTHERN TRUST CORP299,863$10.9M<0.01%-90,94413F-HRTimelineGroup
STEMPOINT CAPITAL LP290,049$10.5M1.81%+131,93713F-HRTimeline
UBS Group AGgroup of 2 filers holding277,177$10.1M+128,631Timeline
Iron Triangle Partners LP257,085$9.33M1.07%new13F-HRTimeline
MARSHALL WACE, LLPin group MARSHALL WACE, LLP249,130$9.04M0.01%new13F-HRTimelineGroup
Squarepoint Ops LLCin group Squarepoint Ops LLC246,804$8.96M0.02%+203,79113F-HRTimelineGroup
SG Americas Securities, LLC230,795$8.38M0.01%+130,75813F-HRTimeline
BARCLAYS PLCin group BARCLAYS PLC223,283$8.1M<0.01%-430,54713F-HRTimelineGroup
Swedbank ABin group Swedbank AB221,400$8.03M0.01%-77,90013F-HR/ATimelineGroup
SUSQUEHANNA INTERNATIONAL GROUP, LLPgroup of 2 filers holding221,300$8.03M+85,985Timeline
Davern Capital Partners, LP210,648$7.64M2.47%13F-HRTimeline
Ikarian Capital, LLCin group Ikarian Capital, LLC200,000$7.26M0.94%new13F-HRTimelineGroup
Russell Investments Group, Ltd.in group Russell Investments Group, Lt…175,361$6.36M0.01%+172,09713F-HRTimelineGroup
Buckley Capital Advisors, LLC174,300$6.33M5.5%13F-HRTimeline
BNP PARIBAS FINANCIAL MARKETSin group BNP PARIBAS FINANCIAL MARKETS172,929$6.28M<0.01%-453,21913F-HRTimelineGroup
Velan Capital Investment Management LP151,000$5.48M3.19%-24,60013F-HRTimeline
Burkehill Global Management, LP150,000$5.44M0.36%013F-HRTimeline
Rhenman & Partners Asset Management AB142,571$5.17M0.48%-22,42913F-HRTimeline
Artia Global Partners LP137,800$5M0.8%+81,20013F-HRTimeline
DIMENSIONAL FUND ADVISORS LPin group DIMENSIONAL FUND ADVISORS LP137,636$4.99M<0.01%-9,14213F-HRTimelineGroup
Brevan Howard Capital Management LPin group Brevan Howard Capital Managem…139,293$4.98M0.1%new13F-HRTimelineGroup
ADAR1 Capital Management, LLCin group ADAR1 Capital Management, LLC136,231$4.94M0.37%+57,99313F-HR/ATimelineGroup
Bank of New York Mellon Corpin group Bank of New York Mellon Corp131,839$4.78M<0.01%+18,04213F-HRTimelineGroup
Rafferty Asset Management, LLC127,917$4.64M0.02%+96,23213F-HRTimeline
SCHRODER INVESTMENT MANAGEMENT GROUP130,592$4.64M<0.01%new13F-HRTimeline
HighVista Strategies LLC124,544$4.52M1.16%-85,28513F-HRTimeline
Nuveen, LLCin group TIAA122,947$4.46M<0.01%+36,03113F-HRTimelineGroup
Simplify Asset Management Inc.114,182$4.14M0.07%-104,54413F-HRTimeline
Nantahala Capital Management, LLCin group Nantahala Capital Management,…113,285$4.11M0.25%-45,42813F-HRTimelineGroup
Trexquant Investment LP112,788$4.09M0.04%+68,81513F-HRTimeline
VOYA INVESTMENT MANAGEMENT LLCin group VOYA INVESTMENT MANAGEMENT LLC112,672$4.09M<0.01%-25,85413F-HRTimelineGroup
Ensign Peak Advisors, Inc112,190$4.07M0.01%+4,55013F-HR/ATimeline
DZ BANK AG Deutsche Zentral Genossensch…in group DZ BANK AG Deutsche Zentral G…111,753$4.06M<0.01%new13F-HRTimelineGroup
Informed Momentum Co LLC96,135$3.49M0.39%-31,41213F-HRTimeline
SILVERARC CAPITAL MANAGEMENT, LLCin group SILVERARC CAPITAL MANAGEMENT,…94,983$3.45M0.5%+14,98313F-HRTimelineGroup
Swiss National Bank90,100$3.27M<0.01%+1,60013F-HRTimeline
PRUDENTIAL FINANCIAL INCin group PRUDENTIAL FINANCIAL INC89,065$3.23M<0.01%+38,64013F-HRTimelineGroup
Verition Fund Management LLC83,840$3.04M0.02%+65,37713F-HRTimeline
MILLENNIUM MANAGEMENT LLCin group MILLENNIUM MANAGEMENT LLC78,625$2.85M<0.01%-325,96413F-HRTimelineGroup
XTX Topco Ltdin group XTX Topco Ltd73,678$2.67M0.07%+54,83813F-HRTimelineGroup
Hennion & Walsh Asset Management, Inc.69,362$2.52M0.09%+16,51413F-HRTimeline
Greenland Capital Management LP69,000$2.5M0.36%-36,85313F-HRTimeline
Blue Owl Capital Holdings LP65,944$2.39M0.74%-35,00013F-HR/ATimeline
ALPS ADVISORS INCin group ALPS ADVISORS INC64,987$2.36M0.01%new13F-HRTimelineGroup
WINTON GROUP Ltdin group WINTON GROUP Ltd64,806$2.35M0.08%new13F-HRTimelineGroup
AQR CAPITAL MANAGEMENT LLCin group AQR CAPITAL MANAGEMENT LLC62,300$2.26M<0.01%+44,17813F-HRTimelineGroup
MOORE CAPITAL MANAGEMENT, LP60,000$2.18M0.04%-105,00013F-HRTimeline
Zimmer Partners, LP57,500$2.09M0.05%-42,50013F-HRTimeline
WELLS FARGO & COMPANY/MNin group WELLS FARGO & COMPANY/MN56,756$2.06M<0.01%+26,70213F-HRTimelineGroup
RHUMBLINE ADVISERS54,284$1.97M<0.01%-1,00713F-HRTimeline
FINDELL CAPITAL MANAGEMENT LLC50,000$1.81M0.6%-200,00013F-HRTimeline
STATE OF WISCONSIN INVESTMENT BOARD49,941$1.81M<0.01%+23,01513F-HRTimeline
Schonfeld Strategic Advisors LLC49,821$1.81M0.01%+35,20313F-HRTimeline
PFM Health Sciences, LP47,637$1.73M0.18%new13F-HRTimeline
ALGERT GLOBAL LLC47,500$1.72M0.03%013F-HR/ATimeline
J. Goldman & Co LP47,288$1.72M0.07%+3,42013F-HRTimeline
PROFUND ADVISORS LLC47,024$1.71M0.05%+39,76813F-HRTimeline
JPMORGAN CHASE & COin group JPMORGAN CHASE & CO46,683$1.69M<0.01%-136,99713F-HRTimelineGroup
AMERIPRISE FINANCIAL INCin group AMERIPRISE FINANCIAL INC46,246$1.68M<0.01%-50,90113F-HRTimelineGroup
Erste Asset Management GmbHin group Erste Asset Management GmbH45,000$1.66M0.01%013F-HRTimelineGroup
Legal & General Group Plcin group Legal & General Group Plc43,938$1.59M<0.01%-1,49113F-HRTimelineGroup
CALIFORNIA STATE TEACHERS RETIREMENT SY…43,348$1.57M<0.01%+6,74913F-HRTimeline
Seven Fleet Capital Management LP42,025$1.53M1.03%13F-HR/ATimeline
TUDOR INVESTMENT CORP ET AL39,046$1.42M0.01%new13F-HRTimeline
DAFNA Capital Management LLC38,490$1.4M0.32%-45,00013F-HRTimeline
DEUTSCHE BANK AG\in group DEUTSCHE BANK AG\37,245$1.35M<0.01%+6,31513F-HRTimelineGroup
HRT FINANCIAL LP37,236$1.35M<0.01%-96,80213F-HRTimeline
VICTORY CAPITAL MANAGEMENT INC32,881$1.19M<0.01%+27,17413F-HRTimeline
Mirae Asset Global Investments Co., Ltd.group of 2 filers holding33,028$1.19M+10,749Timeline
SECTORAL ASSET MANAGEMENT INC31,625$1.15M0.92%-2,26013F-HRTimeline
Y-Intercept (Hong Kong) Ltd31,359$1.14M0.03%-5,01413F-HRTimeline
Allianz Asset Management GmbHin group Allianz SE30,200$1.1M<0.01%-3,50013F-HRTimelineGroup
CANADA PENSION PLAN INVESTMENT BOARD29,600$1.07M<0.01%new13F-HRTimeline
Invesco Ltd.in group Invesco Ltd.29,141$1.06M<0.01%-158,84513F-HRTimelineGroup
MetLife Investment Management, LLCin group MetLife Investment Management…26,005$944K<0.01%+3,29613F-HRTimelineGroup
CenterBook Partners LP26,000$944K0.05%new13F-HRTimeline
DIADEMA PARTNERS LP25,000$907K0.54%new13F-HRTimeline
RAYMOND JAMES FINANCIAL INCin group RAYMOND JAMES FINANCIAL INC24,974$906K<0.01%new13F-HRTimelineGroup
Sigma Planning Corp24,000$871K0.02%new13F-HRTimeline
Atom Investors LP22,330$810K0.06%new13F-HRTimeline
Creative Planningin group Creative Planning21,103$766K<0.01%-1,19213F-HRTimelineGroup
Maven Securities LTDin group Maven Securities LTD20,000$726K0.09%new13F-HRTimelineGroup
Bellevue Group AGin group Bellevue Group AG19,826$719K0.01%-6,77913F-HRTimelineGroup
CITIGROUP INCin group CITIGROUP INC18,315$665K<0.01%-144,85313F-HRTimelineGroup
Quantinno Capital Management LP18,243$662K<0.01%-38413F-HRTimeline
Zurcher Kantonalbank (Zurich Cantonalba…17,348$630K<0.01%-4,97013F-HRTimeline
Twin Securities, Inc.16,737$607K0.23%new13F-HRTimeline
INTECH INVESTMENT MANAGEMENT LLC16,723$607K0.01%new13F-HRTimeline
MANUFACTURERS LIFE INSURANCE COMPANY, T…in group MANUFACTURERS LIFE INSURANCE …16,181$587K<0.01%+1,41513F-HRTimelineGroup
Entropy Technologies, LP16,175$587K0.03%new13F-HRTimeline
State of New Jersey Common Pension Fund…in group State of New Jersey Common Pe…15,584$566K<0.01%new13F-HRTimelineGroup
PSP Research LLC14,818$538K0.47%13F-HRTimeline
FOX RUN MANAGEMENT, L.L.C.14,526$527K0.08%new13F-HRTimeline
Campbell & CO Investment Adviser LLC14,404$523K0.03%new13F-HRTimeline
Handelsbanken Fonder AB14,100$512K<0.01%new13F-HRTimeline
ARIZONA STATE RETIREMENT SYSTEM13,000$472K<0.01%+2,39313F-HRTimeline
China Universal Asset Management Co., L…12,896$468K0.04%+1,27513F-HRTimeline
Police & Firemen's Retirement System of…12,683$460K<0.01%+1,71713F-HRTimeline
NEW YORK STATE COMMON RETIREMENT FUND12,564$456K<0.01%013F-HRTimeline
OPTIMIZE FINANCIAL INC.12,383$449K0.23%+17613F-HRTimeline
ProShare Advisors LLC12,040$437K<0.01%+2,98513F-HRTimeline
Universal- Beteiligungs- und Serviceges…in group Universal- Beteiligungs- und …11,997$435K<0.01%new13F-HRTimelineGroup
AlphaQuest LLC11,328$411K0.02%-1,27713F-HRTimeline
FORA Capital, LLC11,050$401K0.05%+4,72513F-HRTimeline
CreativeOne Wealth, LLCin group CreativeOne Wealth, LLC10,750$390K0.01%013F-HRTimelineGroup
Lion Point Capital, LP10,500$381K1.97%-28,50013F-HRTimeline
Pale Fire Capital SEin group Pale Fire Capital10,354$376K0.05%-522,05313F-HRTimelineGroup
Mariner, LLCin group Mariner, LLC10,230$371K<0.01%-6,17913F-HRTimelineGroup
KLP KAPITALFORVALTNING AS9,600$348K<0.01%+2,90013F-HRTimeline
VIRGINIA RETIREMENT SYSTEMS ET Al9,350$339K<0.01%new13F-HRTimeline
SEI INVESTMENTS COin group SEI INVESTMENTS CO8,780$319K<0.01%-1,08513F-HRTimelineGroup
STATE BOARD OF ADMINISTRATION OF FLORID…7,561$274K<0.01%013F-HRTimeline
BANQUE PICTET & CIE SA7,486$272K<0.01%new13F-HRTimeline
Persistent Asset Partners Ltd7,416$269K0.13%new13F-HRTimeline
Virtus Investment Advisers, LLCin group Virtus Investment Advisers, L…7,209$262K0.07%-41713F-HRTimelineGroup
KINGSWOOD WEALTH ADVISORS, LLC7,074$257K0.01%-9,06913F-HRTimeline
Cinctive Capital Management LP7,037$255K0.01%-64,67613F-HRTimeline
Connor, Clark & Lunn Investment Managem…6,860$249K<0.01%-7,38913F-HRTimeline
TEACHER RETIREMENT SYSTEM OF TEXAS6,781$246K<0.01%-2,90513F-HRTimeline
NEOS Investment Management LLC6,463$235K<0.01%new13F-HRTimeline
Tema ETFs LLC6,463$235K0.02%new13F-HRTimeline
Arrowpoint Investment Partners (Singapo…in group Arrowpoint Investment Partner…6,384$232K0.03%new13F-HRTimelineGroup
CWM, LLCin group CWM, LLC5,098$185K<0.01%-49913F-HRTimelineGroup
SIMPLEX TRADING, LLC4,802$174K<0.01%+37913F-HRTimeline
Caitong International Asset Management …3,823$139K0.03%+3,71513F-HR/ATimeline
Ameritas Investment Partners, Inc.in group Ameritas Investment Partners,…3,798$138K<0.01%+52913F-HRTimelineGroup
ACADIAN ASSET MANAGEMENT LLCin group ACADIAN ASSET MANAGEMENT LLC2,908$104K<0.01%new13F-HRTimelineGroup
PNC Financial Services Group, Inc.in group PNC Financial Services Group,…2,234$81.1K<0.01%013F-HRTimelineGroup
NISA INVESTMENT ADVISORS, LLC1,949$70.7K<0.01%-11613F-HRTimeline
GF FUND MANAGEMENT CO. LTD.1,555$56.4K<0.01%+12913F-HRTimeline
ROYAL BANK OF CANADAin group ROYAL BANK OF CANADA1,529$56K<0.01%+1,10713F-HRTimelineGroup
AMALGAMATED BANK1,470$53K<0.01%+48513F-HRTimeline
OSAIC HOLDINGS, INC.in group OSAIC HOLDINGS, INC.1,155$41.9K<0.01%-27,36913F-HRTimelineGroup
Smartleaf Asset Management LLC1,003$35.6K<0.01%-1413F-HRTimeline
Navalign, LLC900$32.7K0.01%new13F-HRTimeline
COMERICA BANK781$28.3K<0.01%+113F-HRTimeline
Tower Research Capital LLC (TRC)in group Tower Research Capital LLC (T…520$18.9K<0.01%-2,85113F-HRTimelineGroup
Versant Capital Management, Inc513$18.6K<0.01%013F-HRTimeline
Covestor Ltd473$17K0.01%-9413F-HRTimeline
GAMMA Investing LLC451$16.4K<0.01%+1513F-HRTimeline
Pinnacle Wealth Planning Services, Inc.355$12.9K<0.01%new13F-HRTimeline
MassMutual Private Wealth & Trust, FSB319$11.6K<0.01%013F-HRTimeline
LOS ANGELES CAPITAL MANAGEMENT LLC275$11.3K<0.01%new13F-HRTimeline
Sterling Capital Management LLC306$11.1K<0.01%+21113F-HRTimeline
Daiwa Securities Group Inc.in group Daiwa Securities Group Inc.235$9K<0.01%+3613F-HRTimelineGroup
Allworth Financial LP219$7.95K<0.01%+17513F-HRTimeline
Larson Financial Group LLC154$5.59K<0.01%+12413F-HRTimeline
EverSource Wealth Advisors, LLCin group EverSource Wealth Advisors, L…154$5.59K<0.01%+213F-HRTimelineGroup
Rockefeller Capital Management L.P.in group Rockefeller Capital Managemen…134$4.86K<0.01%+10313F-HR/ATimelineGroup