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13F-HR filed by SR One Capital Management, LP

SR One Capital Management, LP filed this 13F-HR for the quarter ended 2025-12-31, filed 2026-02-12, with 13 holding rows worth $706,376,583.

Accession
0001193125-26-048808
Filed
2026-02-12
Accepted by EDGAR
acceptance time not in the bulk data set
Ingested
Source
SEC quarterly data set

Original filing

13F report for Q4 2025

A holdings report, 13 entries on the cover page, a total value of $706,376,583 stated on the cover page (in dollars after the unit check, H1), rows summing to $706,376,583 with VALUE read as dollars as filed, 13F file number 028-21964. The quarter's positions are built on this report. The resolved quarter.

The information table after summing rows of one CUSIP and put or call (H4), with the CUSIP and issuer name as filed. Values in dollars after the unit check (method).

Issuer as filedCUSIPClassAmountValueValue read asType
ZENAS BIOPHARMA INC COM98937L105Stock5,037,854$182,924,479dollars as filed
ARCELLX INC COMMON STOCK03940C100Stock2,346,630$153,000,276dollars as filed
CRISPR THERAPEUTICS AG NAMEN AKTH17182108Stock2,038,763$106,912,732dollars as filed
DESIGN THERAPEUTICS INC25056L103COM6,526,476$61,218,345dollars as filed
MINERALYS THERAPEUTICS INC603170101COM1,563,966$56,756,326dollars as filed
ARS PHARMACEUTICALS INC82835W108COM4,012,903$46,750,320dollars as filed
ORIC PHARMACEUTICALS INC68622P109COM4,514,929$37,753,841dollars as filed
ALUMIS INC022307102COM1,959,896$19,128,585dollars as filed
ORUKA THERAPEUTICS INC COM687604108Stock430,330$13,043,302dollars as filed
OCULIS HOLDING AGH5870P102CMN641,022$12,801,209dollars as filed
ENGENE HOLDINGS INC29286M105COM747,750$6,752,183dollars as filed
NKARTA INC65487U108COMMON STOCK3,333,333$6,166,666dollars as filed
ULTRAGENYX PHARMACEUTICAL IN90400D108COM137,753$3,168,319dollars as filed

Amendment chain

FilingRoleFiledAcceptedIngested
13F-HR 0001193125-26-048808this filing2026-02-12acceptance time not in the bulk data set