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Disclosery

MLYS MINERALYS THERAPEUTICS INC

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COM (common), issuer CIK 1933414

191 managers (194 13F filers) reported a position in MLYS shares at 2025-09-30, 79,335,476 shares in all. 42 filers opened a position and 15 filers sold out during the quarter.

Managers
191
13F filers
194
New
42
Added
69
Reduced
63
Sold out
15
Shares held by filers
79,335,476

Shares held by filers adds up every 13F filer's report, so a share reported by a parent and by its subsidiary counts twice (H9). Managers counts each filer group once.

13D and 13G filers

No 13D or 13G on this security in the data. Structured 13D/G data starts 2024-12-18.

Insider trades

No Form 4 transaction on this security in the data.

13F holders, Q3 2025

Filers in the available 13F reports with a share position at 2025-09-30, filer groups collapsed to one row (method), largest first. Options and principal amounts are left out. A group row states no % of portfolio, since each member reports its own portfolio: the members' percents are listed under it. A value about 1,000 times or 1/1,000 of the price other filers imply is shown as filed but neither ranks the row nor enters a sum.

HolderSharesValue% of portfolioChangeSource
Catalys Pacific, LLC8,903,838$338M96.09%013F-HRTimeline
RA CAPITAL MANAGEMENT, L.P.in group RA CAPITAL MANAGEMENT, L.P.7,323,750$278M3.42%+1,176,47013F-HRTimelineGroup
SAMSARA BIOCAPITAL, LLC6,263,151$237M31.01%+588,23513F-HRTimeline
BlackRock, Inc.in group BlackRock, Inc.3,671,614$139M<0.01%+573,85413F-HRTimelineGroup
VANGUARD GROUP INCin group VANGUARD GROUP INC3,018,999$114M<0.01%+692,55013F-HRTimelineGroup
Caligan Partners LP2,772,654$105M14.59%+755,30213F-HRTimeline
Capital International Investorsin group Capital International Investo…2,393,396$90.8M0.01%-505,62413F-HRTimelineGroup
MONTANOVA CAPITAL, LLC2,132,133$80.9M2.45%+387,64113F-HRTimeline
SR One Capital Management, LP2,113,933$80.2M11.59%-1,014,00013F-HRTimeline
FMR LLCin group FMR LLC2,071,255$78.5M<0.01%+1,766,36913F-HRTimelineGroup
CITADEL ADVISORS LLCin group CITADEL ADVISORS LLC2,067,227$78.4M0.06%+2,052,84513F-HRTimelineGroup
FRANKLIN RESOURCES INCin group Franklin Resources1,809,768$68.6M0.02%+6,17113F-HRTimelineGroup
Point72 Asset Management, L.P.in group Point72 Asset Management, L.P.1,799,628$68.2M0.15%new13F-HRTimelineGroup
Laurion Capital Management LP1,720,445$65.2M8.9%-42,13713F-HRTimeline
FARALLON CAPITAL MANAGEMENT, L.L.C.1,673,053$63.4M0.36%new13F-HR/ATimeline
Integral Health Asset Management, LLC1,500,000$56.9M4.15%-1,200,00013F-HRTimeline
ORBIMED ADVISORS LLCin group ORBIMED ADVISORS LLC1,469,494$55.7M1.34%+709,14313F-HRTimelineGroup
MORGAN STANLEYin group MORGAN STANLEY1,376,998$52.2M<0.01%+789,16813F-HR/ATimelineGroup
STATE STREET CORPin group STATE STREET CORP1,303,023$49.4M<0.01%-140,53613F-HRTimelineGroup
Holocene Advisors, LP1,205,377$45.7M0.11%new13F-HRTimeline
GEODE CAPITAL MANAGEMENT, LLCin group GEODE CAPITAL MANAGEMENT, LLC1,123,411$42.6M<0.01%+168,85113F-HRTimelineGroup
Polar Capital Holdings Plcin group Polar Capital Holdings Plc1,058,776$40.1M0.19%new13F-HRTimelineGroup
BOOTHBAY FUND MANAGEMENT, LLC942,626$35.7M0.9%+125,70013F-HRTimeline
Pictet Asset Management Holding SAin group Pictet Asset Management Holdi…929,169$35.2M0.03%-338,82413F-HRTimelineGroup
ALLIANCEBERNSTEIN L.P.882,415$33.5M0.01%+855,34813F-HRTimeline
AMERICAN CENTURY COMPANIES INCin group AMERICAN CENTURY COMPANIES INC879,682$33.4M0.02%+44,90113F-HRTimelineGroup
WELLINGTON MANAGEMENT GROUP LLPin group WELLINGTON MANAGEMENT GROUP L…783,445$29.7M0.01%+667,99713F-HRTimelineGroup
BANK OF AMERICA CORP /DE/in group BANK OF AMERICA CORP /DE/768,265$29.1M<0.01%+504,90913F-HR/ATimelineGroup
Affinity Asset Advisors, LLC750,000$28.4M2.65%-150,00013F-HRTimeline
GOLDMAN SACHS GROUP INCin group GOLDMAN SACHS GROUP INC711,661$27M<0.01%+84,87413F-HRTimelineGroup
BARCLAYS PLCin group BARCLAYS PLC653,830$24.8M0.01%+509,94613F-HR/ATimelineGroup
BNP PARIBAS FINANCIAL MARKETSin group BNP PARIBAS FINANCIAL MARKETS626,148$23.7M0.02%+622,04013F-HRTimelineGroup
D. E. Shaw & Co., Inc.in group D. E. Shaw & Co., Inc.610,923$23.2M0.02%+36,71613F-HRTimelineGroup
Candriam S.C.A.567,781$21.5M0.11%-256,40613F-HRTimeline
Pale Fire Capital SEin group Pale Fire Capital532,407$20.2M2.21%+85,78113F-HRTimelineGroup
ARMISTICE CAPITAL, LLC507,650$19.3M0.6%+329,65013F-HRTimeline
Parkman Healthcare Partners LLC455,523$17.3M1.9%-8,07813F-HRTimeline
Nearwater Capital Markets, Ltd450,000$17.1M0.23%new13F-HRTimeline
CHARLES SCHWAB INVESTMENT MANAGEMENT INCin group Charles Schwab Trust Co409,187$15.5M<0.01%+84,98213F-HRTimelineGroup
Rock Springs Capital Management LP408,313$15.5M0.91%+83,80013F-HRTimeline
MILLENNIUM MANAGEMENT LLCin group MILLENNIUM MANAGEMENT LLC404,589$15.3M0.01%+161,02013F-HRTimelineGroup
NORTHERN TRUST CORPin group NORTHERN TRUST CORP390,807$14.8M<0.01%+51,78213F-HRTimelineGroup
JENNISON ASSOCIATES LLC376,346$14.3M0.01%-858,97613F-HRTimeline
22NW, LP358,325$13.6M7.07%-201,71713F-HRTimeline
Swedbank ABin group Swedbank AB299,300$11.3M0.01%-84,50013F-HRTimelineGroup
FINDELL CAPITAL MANAGEMENT LLC250,000$9.48M4.33%new13F-HRTimeline
SPHERA FUNDS MANAGEMENT LTD.in group SPHERA FUNDS MANAGEMENT LTD.219,910$8.34M1.98%-261,06413F-HRTimelineGroup
Simplify Asset Management Inc.218,726$8.29M0.17%new13F-HRTimeline
HighVista Strategies LLC209,829$7.96M1.95%+59,69113F-HRTimeline
TANG CAPITAL MANAGEMENT LLCin group TANG CAPITAL MANAGEMENT LLC200,000$7.58M0.29%013F-HRTimelineGroup
Invesco Ltd.in group Invesco Ltd.187,986$7.13M<0.01%+162,24313F-HRTimelineGroup
JPMORGAN CHASE & COin group JPMORGAN CHASE & CO183,680$6.97M<0.01%+158,18013F-HR/ATimelineGroup
Qube Research & Technologies Ltd180,426$6.84M0.01%-170,68713F-HRTimeline
Velan Capital Investment Management LP175,600$6.66M6.25%+1,00013F-HRTimeline
Atika Capital Management LLCin group Atika Capital Management LLC174,000$6.6M0.56%new13F-HRTimelineGroup
MOORE CAPITAL MANAGEMENT, LP165,000$6.26M0.12%new13F-HRTimeline
Rhenman & Partners Asset Management AB165,000$6.26M0.69%new13F-HRTimeline
CITIGROUP INCin group CITIGROUP INC163,168$6.19M<0.01%+136,05013F-HRTimelineGroup
Nantahala Capital Management, LLCin group Nantahala Capital Management,…158,713$6.02M0.37%-195,26913F-HRTimelineGroup
STEMPOINT CAPITAL LP158,112$6M1.21%-473,47413F-HRTimeline
Burkehill Global Management, LP150,000$5.69M0.32%new13F-HRTimeline
UBS Group AGgroup of 2 filers holding148,546$5.63M+9,003Timeline
DIMENSIONAL FUND ADVISORS LPin group DIMENSIONAL FUND ADVISORS LP146,778$5.57M<0.01%-40,60613F-HRTimelineGroup
VOYA INVESTMENT MANAGEMENT LLCin group VOYA INVESTMENT MANAGEMENT LLC138,526$5.25M0.01%+88,05013F-HRTimelineGroup
SUSQUEHANNA INTERNATIONAL GROUP, LLPgroup of 2 filers holding135,315$5.13M-81,905Timeline
HRT FINANCIAL LP134,038$5.08M0.02%+123,96113F-HRTimeline
Informed Momentum Co LLC127,547$4.76M0.55%new13F-HRTimeline
Jain Global LLC120,854$4.58M0.06%new13F-HRTimeline
Bank of New York Mellon Corpin group Bank of New York Mellon Corp113,797$4.32M<0.01%+17,38213F-HRTimelineGroup
Ensign Peak Advisors, Inc107,640$4.08M0.01%013F-HR/ATimeline
Greenland Capital Management LP105,853$4.01M0.59%+95,85313F-HRTimeline
ADAGE CAPITAL PARTNERS GP, L.L.C.in group ADAGE CAPITAL PARTNERS GP, L.…105,000$3.98M0.01%new13F-HRTimelineGroup
Blue Owl Capital Holdings LP100,944$3.83M1.19%-235,00013F-HRTimeline
SG Americas Securities, LLC100,037$3.79M0.01%-23,95013F-HRTimeline
Zimmer Partners, LP100,000$3.79M0.09%-62,73313F-HRTimeline
AMERIPRISE FINANCIAL INCin group AMERIPRISE FINANCIAL INC97,147$3.68M<0.01%+46,29013F-HRTimelineGroup
Swiss National Bank88,500$3.36M<0.01%+26,60013F-HRTimeline
Nuveen, LLCin group TIAA86,916$3.3M<0.01%+9,26913F-HRTimelineGroup
DAFNA Capital Management LLC83,490$3.17M0.78%-288,03313F-HRTimeline
SILVERARC CAPITAL MANAGEMENT, LLCin group SILVERARC CAPITAL MANAGEMENT,…80,000$3.03M0.44%-35,28213F-HRTimelineGroup
ADAR1 Capital Management, LLCin group ADAR1 Capital Management, LLC78,238$2.97M0.29%-223,88713F-HRTimelineGroup
Hudson Bay Capital Management LPin group Hudson Bay Capital Management…75,768$2.87M0.02%new13F-HR/ATimelineGroup
Cinctive Capital Management LP71,713$2.72M0.14%+55,60013F-HRTimeline
Artia Global Partners LP56,600$2.15M0.38%+15,50013F-HR/ATimeline
RHUMBLINE ADVISERS55,291$2.1M<0.01%+1,69513F-HRTimeline
Hennion & Walsh Asset Management, Inc.52,848$2M0.07%+21,75313F-HRTimeline
PRUDENTIAL FINANCIAL INCin group PRUDENTIAL FINANCIAL INC50,425$1.91M<0.01%-301,80013F-HRTimelineGroup
ALGERT GLOBAL LLC47,500$1.8M0.03%new13F-HR/ATimeline
RENAISSANCE TECHNOLOGIES LLC47,400$1.8M<0.01%-129,52613F-HRTimeline
Erste Asset Management GmbHin group Erste Asset Management GmbH45,000$1.77M0.02%013F-HRTimelineGroup
Legal & General Group Plcin group Legal & General Group Plc45,429$1.72M<0.01%+9,38013F-HRTimelineGroup
Trexquant Investment LP43,973$1.67M0.02%-138,69213F-HRTimeline
J. Goldman & Co LP43,868$1.66M0.06%-13,76713F-HRTimeline
Squarepoint Ops LLCin group Squarepoint Ops LLC43,013$1.63M<0.01%+31,49813F-HRTimelineGroup
CAPSTONE INVESTMENT ADVISORS, LLCin group CAPSTONE INVESTMENT ADVISORS,…42,276$1.6M0.01%new13F-HRTimelineGroup
Resolute Capital Asset Partners LLC40,000$1.52M0.79%new13F-HRTimeline
Lion Point Capital, LP39,000$1.48M8.4%-40,00013F-HRTimeline
JANE STREET GROUP, LLCin group JANE STREET GROUP, LLC37,145$1.41M<0.01%new13F-HRTimelineGroup
CALIFORNIA STATE TEACHERS RETIREMENT SY…36,599$1.39M<0.01%+713F-HRTimeline
Y-Intercept (Hong Kong) Ltd36,373$1.38M0.03%+15,09313F-HRTimeline
SECTORAL ASSET MANAGEMENT INC33,885$1.28M0.79%-348,53013F-HRTimeline
Allianz Asset Management GmbHin group Allianz SE33,700$1.28M<0.01%+21,40013F-HRTimelineGroup
Rafferty Asset Management, LLC31,685$1.2M<0.01%-25,69013F-HRTimeline
DEUTSCHE BANK AG\in group DEUTSCHE BANK AG\30,930$1.17M<0.01%-425,98413F-HRTimelineGroup
WELLS FARGO & COMPANY/MNin group WELLS FARGO & COMPANY/MN30,054$1.14M<0.01%-1,70313F-HRTimelineGroup
STATE OF WISCONSIN INVESTMENT BOARD26,926$1.02M<0.01%+2,37513F-HRTimeline
Bellevue Group AGin group Bellevue Group AG26,605$1.01M0.02%+11,04913F-HRTimelineGroup
MetLife Investment Management, LLCin group MetLife Investment Management…22,709$861K<0.01%-1,30513F-HRTimelineGroup
Mirae Asset Global Investments Co., Ltd.group of 2 filers holding22,279$847K-4,476Timeline
Zurcher Kantonalbank (Zurich Cantonalba…22,318$846K<0.01%-55613F-HRTimeline
Creative Planningin group Creative Planning22,295$845K<0.01%-2,56613F-HRTimelineGroup
PRICE T ROWE ASSOCIATES INC /MD/21,383$811K<0.01%+1,81513F-HRTimeline
JANUS HENDERSON GROUP PLCin group Janus Henderson19,848$753K<0.01%+8,24813F-HRTimelineGroup
MARK ASSET MANAGEMENT LP19,465$738K0.08%new13F-HRTimeline
XTX Topco Ltdin group XTX Topco Ltd18,840$714K0.04%new13F-HRTimelineGroup
Quantinno Capital Management LP18,627$706K<0.01%+5,03013F-HRTimeline
Verition Fund Management LLC18,463$700K<0.01%new13F-HRTimeline
AQR CAPITAL MANAGEMENT LLCin group AQR CAPITAL MANAGEMENT LLC18,122$687K<0.01%-9,77913F-HRTimelineGroup
Mariner, LLCin group Mariner, LLC16,409$622K<0.01%-12,29513F-HRTimelineGroup
KINGSWOOD WEALTH ADVISORS, LLC16,143$612K0.04%new13F-HRTimeline
Balyasny Asset Management L.P.in group Balyasny Asset Management15,268$579K<0.01%-190,45513F-HRTimelineGroup
MANUFACTURERS LIFE INSURANCE COMPANY, T…in group MANUFACTURERS LIFE INSURANCE …14,766$560K<0.01%-913F-HRTimelineGroup
Schonfeld Strategic Advisors LLC14,618$554K<0.01%-238,58113F-HRTimeline
Connor, Clark & Lunn Investment Managem…14,249$540K<0.01%new13F-HRTimeline
Caption Management, LLC13,000$493K0.03%-20,00013F-HRTimeline
AlphaQuest LLC12,605$478K0.03%-2,23613F-HRTimeline
NEW YORK STATE COMMON RETIREMENT FUND12,564$476K<0.01%+4,80013F-HRTimeline
OPTIMIZE FINANCIAL INC.12,207$463K0.24%new13F-HRTimeline
OSAIC HOLDINGS, INC.in group OSAIC HOLDINGS, INC.28,524$448K<0.01%+27,19913F-HRTimelineGroup
China Universal Asset Management Co., L…11,621$441K0.04%-1,46913F-HRTimeline
Police & Firemen's Retirement System of…10,966$416K<0.01%+1,73213F-HRTimeline
CreativeOne Wealth, LLCin group CreativeOne Wealth, LLC10,750$408K0.01%013F-HRTimelineGroup
ARIZONA STATE RETIREMENT SYSTEM10,607$402K<0.01%new13F-HRTimeline
SEI INVESTMENTS COin group SEI INVESTMENTS CO9,865$374K<0.01%new13F-HRTimelineGroup
TEACHER RETIREMENT SYSTEM OF TEXAS9,686$367K<0.01%new13F-HRTimeline
OXFORD ASSET MANAGEMENT LLP9,123$346K0.11%new13F-HRTimelineThe filing omitted confidential holdings, a later amendment may add them.
ProShare Advisors LLC9,055$343K<0.01%-1,40213F-HRTimeline
Scientech Research LLC7,964$302K0.11%new13F-HRTimeline
Virtus Investment Advisers, LLCin group Virtus Investment Advisers, L…7,626$289K0.08%+1,32413F-HRTimelineGroup
STATE BOARD OF ADMINISTRATION OF FLORID…7,561$287K<0.01%new13F-HRTimeline
PROFUND ADVISORS LLC7,256$275K0.01%-4,87513F-HRTimeline
KLP KAPITALFORVALTNING AS6,700$254K<0.01%013F-HRTimeline
ExodusPoint Capital Management, LP6,670$253K<0.01%-165,88213F-HRTimeline
Bridgefront Capital, LLC6,338$240K0.07%new13F-HRTimeline
FORA Capital, LLC6,325$240K0.04%new13F-HRTimeline
VICTORY CAPITAL MANAGEMENT INC5,707$216K<0.01%new13F-HRTimeline
CWM, LLCin group CWM, LLC5,597$212K<0.01%-65413F-HRTimelineGroup
LETKO, BROSSEAU & ASSOCIATES INC5,475$208K<0.01%-11,02513F-HRTimeline
SIMPLEX TRADING, LLC4,423$167K<0.01%new13F-HRTimeline
Point72 (DIFC) Ltd4,037$153K0.01%new13F-HRTimeline
Tower Research Capital LLC (TRC)in group Tower Research Capital LLC (T…3,371$128K<0.01%+62213F-HRTimelineGroup
Ameritas Investment Partners, Inc.in group Ameritas Investment Partners,…3,269$124K<0.01%-72613F-HRTimelineGroup
Russell Investments Group, Ltd.in group Russell Investments Group, Lt…3,264$124K<0.01%+3,24113F-HRTimelineGroup
PNC Financial Services Group, Inc.in group PNC Financial Services Group,…2,234$84.7K<0.01%013F-HRTimelineGroup
NISA INVESTMENT ADVISORS, LLC2,065$78.3K<0.01%013F-HRTimeline
GF FUND MANAGEMENT CO. LTD.1,426$54.1K<0.01%+15213F-HRTimeline
SBI Securities Co., Ltd.1,126$42.7K<0.01%-59813F-HRTimeline
Smartleaf Asset Management LLC1,017$40K<0.01%+67613F-HRTimeline
AMALGAMATED BANK985$37K<0.01%013F-HRTimeline
COMERICA BANK780$29.6K<0.01%-2313F-HRTimeline
Covestor Ltd567$21K0.01%-17213F-HRTimeline
Versant Capital Management, Inc513$19.5K<0.01%013F-HRTimeline
GAMMA Investing LLC436$16.5K<0.01%-113F-HRTimeline
ROYAL BANK OF CANADAin group ROYAL BANK OF CANADA422$16K<0.01%-9,14113F-HRTimelineGroup
MassMutual Private Wealth & Trust, FSB319$12.1K<0.01%013F-HRTimeline
Optiver Holding B.V.in group Optiver Holding B.V.286$10.8K<0.01%new13F-HRTimelineGroup
Arax Advisory Partners270$10.2K<0.01%new13F-HRTimeline
Daiwa Securities Group Inc.in group Daiwa Securities Group Inc.199$8K<0.01%-3513F-HRTimelineGroup
US BANCORP \DE\in group US BANCORP \DE\204$7.74K<0.01%+3013F-HRTimelineGroup
EverSource Wealth Advisors, LLCin group EverSource Wealth Advisors, L…152$5.76K<0.01%-20513F-HRTimelineGroup
Caitong International Asset Management …108$4.09K<0.01%-8413F-HRTimeline
FSA Wealth Management LLC100$3.79K<0.01%new13F-HRTimeline
Sterling Capital Management LLC95$3.6K<0.01%013F-HRTimeline
True Wealth Design, LLC76$2.88K<0.01%013F-HRTimeline
Avion Wealth78$2K<0.01%013F-HRTimeline
ROTHSCHILD INVESTMENT LLC50$1.9K<0.01%-2513F-HRTimeline
Private Wealth Management Group, LLC50$1.9K<0.01%013F-HRTimeline
Allworth Financial LP44$1.67K<0.01%+1013F-HRTimeline
Quantbot Technologies LP39$1.48K<0.01%new13F-HRTimeline
Rise Advisors, LLC37$1.4K<0.01%-2513F-HRTimeline
Parkside Financial Bank & Trust35$1.33K<0.01%013F-HRTimeline
Farther Finance Advisors, LLC33$1.25K<0.01%+1613F-HRTimeline
Rockefeller Capital Management L.P.in group Rockefeller Capital Managemen…31$1.18K<0.01%new13F-HRTimelineGroup
Larson Financial Group LLC30$1.14K<0.01%+2413F-HRTimeline
Parallel Advisors, LLC22$834<0.01%013F-HRTimeline
FEDERATED HERMES, INC.in group FEDERATED HERMES, INC.21$796<0.01%-16,50713F-HRTimelineGroup
MAI Capital Management18$683<0.01%013F-HRTimeline
QUADRANT CAPITAL GROUP LLC10$380<0.01%new13F-HRTimeline
IFP Advisors, Inc2$76<0.01%+213F-HR/ATimeline
Essential Partners LLC1$38<0.01%013F-HRTimeline
NOMURA ASSET MANAGEMENT CO LTDin group NOMURA ASSET MANAGEMENT CO LTD0$00%013F-HRTimelineGroupValue filed as zero, left out of ratios. Amount filed as zero, left out of ratios.