13F-HR filed by Ikarian Capital, LLC
Ikarian Capital, LLC filed this 13F-HR for the quarter ended 2026-06-30, filed 2026-08-14, with 156 holding rows worth $928,174,362.
- Accession
- 0001420506-26-001820
- Filer
- CIK 1778253
- Filed
- 2026-08-14
- Accepted by EDGAR
- acceptance time not in the bulk data set
- Ingested
- Source
- SEC quarterly data set
13F report for Q2 2026
A holdings report, 156 entries on the cover page, a total value of $928,174,362 stated on the cover page (in dollars after the unit check, H1), rows summing to $928,174,362 with VALUE read as dollars as filed, 13F file number 028-19721. The quarter's positions are built on this report. The resolved quarter.
The information table after summing rows of one CUSIP and put or call (H4), with the CUSIP and issuer name as filed. Values in dollars after the unit check (method).
| Issuer as filed | CUSIP | Class | Amount | Value | Value read as | Type |
|---|---|---|---|---|---|---|
| SPDR SER TR | 78464A870 | S&P BIOTECH | 300,000 | $47,475,000 | dollars as filed | put |
| ABIVAX SA- | 00370M103 | SPONSORED ADS | 341,100 | $45,454,986 | dollars as filed | call |
| ABIVAX SA- | 00370M103 | SPONSORED ADS | 328,635 | $43,352,978 | dollars as filed | |
| KODIAK SCIENCES INC | 50015M109 | COM | 1,059,730 | $41,287,080 | dollars as filed | |
| ABIVAX SA- | 00370M103 | SPONSORED ADS | 250,000 | $33,315,000 | dollars as filed | put |
| IONIS PHARMACEUTICALS INC COM | 462222100 | Stock | 400,000 | $31,716,000 | dollars as filed | call |
| MODERNA INC | 60770K107 | COM | 400,000 | $28,012,000 | dollars as filed | put |
| ALUMIS INC | 022307102 | COM | 870,548 | $24,497,220 | dollars as filed | |
| PRAXIS PRECISION MEDICINES I | 74006W207 | COM NEW | 72,842 | $24,386,773 | dollars as filed | |
| IONIS PHARMACEUTICALS INC COM | 462222100 | Stock | 300,000 | $23,787,000 | dollars as filed | put |
| VAXCYTE INC COM | 92243G108 | Stock | 388,682 | $22,594,085 | dollars as filed | |
| ANI PHARMACEUTICALS INC | 00182C103 | COM | 272,085 | $22,523,196 | dollars as filed | |
| CELLDEX THERAPEUTICS INC NEW | 15117B202 | COM NEW | 478,500 | $17,804,985 | dollars as filed | |
| ARCUS BIOSCIENCES INC | 03969F109 | COM | 504,559 | $15,555,555 | dollars as filed | |
| RELMADA THERAPEUTICS INC | 75955J402 | COMMON STOCK | 2,148,359 | $14,866,644 | dollars as filed | |
| CAPRICOR THERAPEUTICS INC | 14070B309 | COMMON STOCK | 604,215 | $14,549,497 | dollars as filed | |
| COGENT BIOSCIENCES INC | 19240Q201 | COM | 370,084 | $14,322,251 | dollars as filed | |
| NEWAMSTERDAM PHARMA COMPANY | N62509959 | PUT | 400,000 | $13,556,000 | dollars as filed | put |
| VERA THERAPEUTICS INC | 92337R101 | COMMON STOCK | 310,000 | $13,302,100 | dollars as filed | |
| CONTINEUM THERAPEUTICS INC CL A | 21217B100 | Stock | 807,874 | $13,241,056 | dollars as filed | |
| TENAX THERAPEUTICS INC | 88032L605 | COM NEW | 787,600 | $11,459,580 | dollars as filed | |
| C4 THERAPEUTICS INC | 12529R107 | COM STK | 2,433,000 | $11,362,110 | dollars as filed | |
| MAZE THERAPEUTICS INC COM | 578784100 | Stock | 378,999 | $11,309,331 | dollars as filed | |
| BIOHAVEN LTD | G1110E107 | COM | 748,181 | $11,132,933 | dollars as filed | |
| CONNECT BIOPHARMA HLDGS LTD | G23549101 | SHS | 4,538,534 | $10,801,710 | dollars as filed | |
| ALTO NEUROSCIENCE INC COM SHS | 02157Q109 | Stock | 407,338 | $10,749,651 | dollars as filed | |
| PHARVARIS NV | N69605108 | COMMON STOCK | 308,856 | $10,680,241 | dollars as filed | |
| ALUMIS INC | 022307102 | COM | 356,300 | $10,026,282 | dollars as filed | call |
| JADE BIOSCIENCES INC | 008064206 | COM NEW | 427,349 | $9,495,694 | dollars as filed | |
| DAMORA THERAPEUTICS INC | 36322Q206 | COMMON STOCK | 335,710 | $8,731,816 | dollars as filed | |
| KODIAK SCIENCES INC | 50015M109 | COM | 217,700 | $8,481,592 | dollars as filed | call |
| CAPRICOR THERAPEUTICS INC | 14070B309 | COMMON STOCK | 350,000 | $8,428,000 | dollars as filed | call |
| ARROWHEAD PHARMACEUTICALS IN | 04280A100 | COM | 100,000 | $8,151,000 | dollars as filed | put |
| VIRIDIAN THERAPEUTICS INC | 92790C104 | COM | 425,000 | $7,807,251 | dollars as filed | |
| PELTHOS THERAPEUTICS INC | 171126204 | COM SHS | 256,598 | $7,251,459 | dollars as filed | |
| ZURA BIO LTD | G9TY5A101 | COMMON STOCK | 1,218,492 | $7,189,102 | dollars as filed | |
| TECTONIC THERAPEUTIC INC | 878972108 | COMMON STOCK | 205,837 | $7,075,647 | dollars as filed | |
| PRAXIS PRECISION MEDICINES I | 74006W207 | COM NEW | 20,000 | $6,695,800 | dollars as filed | call |
| SPRUCE BIOSCIENCES INC | 85209E208 | COM NEW | 121,356 | $6,553,224 | dollars as filed | |
| HIMS & HERS HEALTH INC | 433000106 | COM CL A | 188,381 | $6,531,170 | dollars as filed | |
| ENLIVEN THERAPEUTICS INC COM | 29337E102 | Stock | 126,541 | $6,421,957 | dollars as filed | |
| PROQR THERAPEUTICS NV | N71542109 | SHS EURO | 3,425,930 | $6,372,230 | dollars as filed | |
| BRIGHT MINDS BIOSCIENCES INC | 10919W405 | COMMON STOCK | 88,951 | $6,244,361 | dollars as filed | |
| OVID THERAPEUTICS INC | 690469101 | COMMON STOCK | 2,269,704 | $6,105,503 | dollars as filed | |
| OCUGEN INC | 67577C105 | COMMON STOCK | 3,962,972 | $6,063,348 | dollars as filed | |
| ALPHA COGNITION INC | 02074J501 | COM NEW | 836,259 | $6,037,790 | dollars as filed | |
| KYMERA THERAPEUTICS INC | 501575104 | COM | 50,400 | $5,779,368 | dollars as filed | put |
| HARROW INC | 415858109 | COM | 135,775 | $5,766,364 | dollars as filed | |
| KAZIA THERAPEUTICS LTD | 48669G303 | SPONSORED ADS | 396,201 | $5,578,510 | dollars as filed | |
| ULTRAGENYX PHARMACEUTICAL IN | 90400D108 | COM | 165,617 | $5,529,952 | dollars as filed | |
| Q32 BIO INC | 746964105 | Common Stock | 430,000 | $5,478,200 | dollars as filed | |
| TENAX THERAPEUTICS INC | 88032L605 | COM NEW | 373,100 | $5,428,605 | dollars as filed | call |
| EUPRAXIA PHARMACEUTICALS INC | 29842P105 | COM 298736 AL 3 EURONET WORLDWIDE INC NOTE 0.750% 3/1 | 809,741 | $5,352,388 | dollars as filed | |
| EYEPOINT INC COM NEW | 30233G209 | Stock | 370,400 | $5,296,720 | dollars as filed | put |
| EYEPOINT INC COM NEW | 30233G209 | Stock | 370,400 | $5,296,720 | dollars as filed | call |
| SELLAS LIFE SCIENCES GROUP I | 81642T209 | COM NEW | 354,700 | $5,235,372 | dollars as filed | put |
| BIOAGE LABS INC COM | 09077V100 | Stock | 200,000 | $4,901,999 | dollars as filed | |
| REZOLUTE INC | 76200L309 | COMMON STOCK | 935,012 | $4,862,062 | dollars as filed | |
| OLEMA PHARMACEUTICALS INC | 68062P106 | COM | 383,281 | $4,794,845 | dollars as filed | |
| SIONNA THERAPEUTICS INC | 829401108 | COMMON STOCK | 107,500 | $4,728,925 | dollars as filed | put |
| MONOPAR THERAPEUTICS INC | 61023L207 | COMMON STOCK | 47,861 | $4,431,450 | dollars as filed | |
| BRIDGEBIO PHARMA INC | 10806X102 | COM | 57,417 | $4,276,418 | dollars as filed | |
| CELLDEX THERAPEUTICS INC NEW | 15117B202 | COM NEW | 114,000 | $4,241,940 | dollars as filed | put |
| INVENTIVA SA | 46124U107 | ADS | 1,129,101 | $4,152,521 | dollars as filed | |
| ABSCI CORPORATION | 00091E109 | COM | 353,772 | $4,100,217 | dollars as filed | |
| ALECTOR INC | 014442107 | COMMON STOCK | 1,982,606 | $3,985,038 | dollars as filed | |
| CLIMB BIO INC | 28658R106 | COMMON STOCK | 300,000 | $3,912,000 | dollars as filed | |
| FULCRUM THERAPEUTICS INC | 359616109 | COMMON STOCK | 1,049,161 | $3,839,929 | dollars as filed | |
| CARDIOL THERAPEUTICS INC | 14161Y200 | COM CL A | 3,325,000 | $3,524,500 | dollars as filed | |
| CUE BIOPHARMA INC | 22978P205 | COM | 104,364 | $3,293,728 | dollars as filed | |
| CUMBERLAND PHARMACEUTICALS I | 230770109 | COM | 503,153 | $3,260,431 | dollars as filed | |
| ARROWHEAD PHARMACEUTICALS IN | 04280A100 | COM | 38,278 | $3,120,040 | dollars as filed | |
| VERA THERAPEUTICS INC | 92337R101 | COMMON STOCK | 71,700 | $3,076,647 | dollars as filed | call |
| REIN THERAPEUTICS INC | 00887A204 | COM NEW | 2,950,000 | $3,068,000 | dollars as filed | |
| ARVINAS INC | 04335A105 | COM | 358,257 | $2,977,115 | dollars as filed | |
| ACUMEN PHARMACEUTICALS INC | 00509G209 | CMN | 1,053,797 | $2,813,638 | dollars as filed | |
| PROMIS NEUROSCIENCES INC | 74346M505 | COM SHS | 205,000 | $2,697,801 | dollars as filed | |
| Q32 BIO INC | 746964105 | Common Stock | 200,000 | $2,548,000 | dollars as filed | put |
| OLEMA PHARMACEUTICALS INC | 68062P106 | COM | 200,000 | $2,502,000 | dollars as filed | call |
| ANNEXON INC | 03589W102 | COM | 430,244 | $2,456,693 | dollars as filed | |
| Bristol-Myers Squibb Company | 110122108 | COM | 42,500 | $2,448,850 | dollars as filed | put |
| LEXEO THERAPEUTICS INC | 52886X107 | COMMON STOCK | 513,011 | $2,388,066 | dollars as filed | |
| DELCATH SYSTEMS INC | 24661P807 | COMMON STOCK | 185,667 | $2,337,548 | dollars as filed | |
| INVIVYD INC | 00534A102 | COMMON STOCK | 2,656,570 | $2,317,592 | dollars as filed | |
| UNIQURE NV | N90064901 | CALL | 49,800 | $2,293,788 | dollars as filed | call |
| CABALETTA BIO INC | 12674W109 | COMMON STOCK | 700,000 | $2,177,000 | dollars as filed | |
| NEUMORA THERAPEUTICS INC. | 640979100 | COM | 1,278,408 | $2,173,294 | dollars as filed | |
| AMYLYX PHARMACEUTICALS INC | 03237H101 | COM | 117,500 | $2,110,301 | dollars as filed | |
| TARSUS PHARMACEUTICALS INC | 87650L103 | COMMON STOCK | 31,166 | $1,961,588 | dollars as filed | |
| SILENCE THERAPEUTICS PLC | 82686Q101 | ADS | 830,784 | $1,827,725 | dollars as filed | |
| JOURNEY MED CORP | 48115J109 | COM | 251,436 | $1,780,168 | dollars as filed | |
| DBV TECHNOLOGIES S A | 23306J309 | SPONSORED ADS | 525,000 | $1,690,953 | dollars as filed | |
| IBIO INC | 451033708 | CMN | 957,062 | $1,674,859 | dollars as filed | |
| AVALO THERAPEUTICS INC | 05338F306 | COMMON STOCK | 90,183 | $1,666,581 | dollars as filed | |
| ANTERIS TECHNOLOGIES GLOBAL | 03675P102 | COMMON STOCK | 166,571 | $1,640,724 | dollars as filed | |
| PALISADE BIO INC | 696389402 | COMMON STOCK | 750,000 | $1,567,500 | dollars as filed | |
| AMANAT ACQUISITION CORP | G0375M101 | CL A ORD | 150,000 | $1,524,000 | dollars as filed | |
| KALARIS THERAPEUTICS INC | 482929106 | COM | 360,000 | $1,465,201 | dollars as filed | |
| QUINCE THERAPEUTICS INC COM | 22053A305 | Stock | 72,251 | $1,314,245 | dollars as filed | |
| LIPOCINE INC NEW | 53630X203 | COM NEW | 508,556 | $1,301,902 | dollars as filed | |
| IMMUNOME INC | 45257U108 | COM | 60,000 | $1,271,401 | dollars as filed | |
| PLIANT THERAPEUTICS INC | 729139105 | COM | 1,000,000 | $1,140,000 | dollars as filed | |
| IMMUNIC INC | 4525EP200 | COM NEW | 67,464 | $1,036,922 | dollars as filed | |
| QUOIN PHARMACEUTICALS LTD | 74907L409 | SPONSORED ADS | 211,538 | $1,023,844 | dollars as filed | |
| DISC MEDICINE INC COM | 254604101 | Stock | 13,300 | $972,762 | dollars as filed | put |
| DISC MEDICINE INC COM | 254604101 | Stock | 13,300 | $972,762 | dollars as filed | call |
| EQUILLIUM INC | 29446K106 | COM | 303,555 | $971,376 | dollars as filed | |
| NEURONETICS INC | 64131A105 | COM | 701,182 | $911,537 | dollars as filed | |
| FAETH THERAPEUTICS INC | 81728A207 | COM NEW | 35,386 | $884,650 | dollars as filed | |
| FRACTYL HEALTH INC | 35168W103 | COM | 1,100,000 | $873,840 | dollars as filed | |
| CYBIN INC | 23256X407 | COM NEW | 132,153 | $873,532 | dollars as filed | |
| FIRST TRACKS BIOTHERAPEUTICS | 337185102 | ORD SHS *A* | 42,775 | $860,633 | dollars as filed | |
| VERASTEM INC | 92337C203 | COMMON STOCK | 213,865 | $816,965 | dollars as filed | |
| DIREXION SHARES ETF TRUST | 25461H853 | CMN | 105,822 | $815,887 | dollars as filed | |
| PEPGEN INC COM | 713317105 | Stock | 447,165 | $804,897 | dollars as filed | |
| ACADIA PHARMACEUTICALS INC | 004225108 | COM | 28,099 | $710,905 | dollars as filed | |
| CNS PHARMACEUTICALS INC | 18978H508 | COM | 135,830 | $649,267 | dollars as filed | |
| LYELL IMMUNOPHARMA INC COM NEW | 55083R203 | Stock | 41,081 | $577,188 | dollars as filed | |
| WAVE LIFE SCIENCES LTD SHS | Y95308105 | Stock | 85,285 | $495,507 | dollars as filed | |
| IMMATICS N.V | N44445109 | SHS | 48,569 | $492,003 | dollars as filed | |
| PASSAGE BIO INC | 702712209 | COM NEW | 99,517 | $485,643 | dollars as filed | |
| NEXTCURE INC | 65343E207 | COM NEW | 288,303 | $461,284 | dollars as filed | |
| FORTE BIOSCIENCES INC | 34962G208 | COMMON STOCK | 20,972 | $445,655 | dollars as filed | |
| SOLID BIOSCIENCES INC | 83422E204 | COMMON STOCK | 42,956 | $429,130 | dollars as filed | |
| Elicio Therapeutics Inc Com | 28657F103 | LST Equity Option | 107,100 | $418,761 | dollars as filed | put |
| Elicio Therapeutics Inc Com | 28657F103 | LST Equity Option | 107,100 | $418,761 | dollars as filed | call |
| TRAWS PHARMA INC | 68232V884 | COM NEW | 478,142 | $403,217 | dollars as filed | |
| LEXICON PHARMACEUTICALS INC | 528872302 | COMMON STOCK | 164,674 | $395,218 | dollars as filed | |
| Elicio Therapeutics Inc Com | 28657F103 | LST Equity Option | 100,000 | $391,000 | dollars as filed | |
| Adlai Nortye | 00704R109 | SPONSORED ADS | 33,899 | $389,839 | dollars as filed | |
| INMED PHARMACEUTICALS INC | 457637700 | COM NEW | 245,025 | $379,788 | dollars as filed | |
| VIKING THERAPEUTICS INC | 92686J106 | COM | 9,717 | $379,061 | dollars as filed | |
| MACROGENICS INC | 556099109 | COM | 74,893 | $346,006 | dollars as filed | |
| PRAXIS PRECISION MEDICINES I | 74006W207 | COM NEW | 900 | $301,311 | dollars as filed | put |
| TENAX THERAPEUTICS INC | 88032L605 | COM NEW | 16,500 | $240,075 | dollars as filed | put |
| HYPERLIQUID STRATEGIES | 44916Y106 | COMMON STOCK | 30,001 | $236,108 | dollars as filed | |
| EVAXION AS | 29970R303 | SPONSORED ADS | 74,698 | $231,564 | dollars as filed | |
| CARTESIAN THERAPEUTICS INC | 816212302 | COMMON STOCK | 20,807 | $216,809 | dollars as filed | |
| COMPASS PATHWAYS PLC | 20451W101 | SPONSORED ADS | 15,000 | $212,250 | dollars as filed | |
| NEUPHORIA THERAPEUTICS INC | 64136E102 | COM | 47,443 | $207,326 | dollars as filed | |
| VOYAGER THERAPEUTICS INC | 92915B106 | COMMON STOCK | 53,063 | $185,722 | dollars as filed | |
| VYNE THERAPEUTICS INC | 92941V308 | COM | 264,912 | $172,379 | dollars as filed | |
| BIOCRYST PHARMACEUTICALS INC COM | 09058V103 | Stock | 16,756 | $167,560 | dollars as filed | |
| ENVERIC BIOSCIENCES INC | 29405E505 | COM SHS | 100,002 | $138,003 | dollars as filed | |
| PMV PHARMACEUTICALS INC | 69353Y103 | COM | 89,136 | $119,442 | dollars as filed | |
| VISTAGEN THERAPEUTICS INC | 92840H400 | COM | 519,077 | $117,311 | dollars as filed | |
| CHEMOMAB THERAPEUTICS LTD | 16385C203 | SPONSORED ADS | 51,793 | $83,904 | dollars as filed | |
| NYXOAH S A | B6S7WD106 | SHS | 47,358 | $80,035 | dollars as filed | |
| AIRSCULPT TECHNOLOGIES INC | 009496100 | COMMON STOCK | 16,398 | $73,792 | dollars as filed | |
| MANGOCEUTICALS INC | 56270V205 | CMN | 138,146 | $52,496 | dollars as filed | |
| COMPASS THERAPEUTICS INC | 20454B104 | COM | 18,000 | $39,419 | dollars as filed | |
| THERIVA BIOLOGICS INC | 87164U508 | COM NEW | 112,076 | $28,041 | dollars as filed | |
| GLUCOTRACK INC | 45824Q804 | COM NEW | 45,830 | $14,621 | dollars as filed | |
| AETHLON MED INC | 00808Y604 | COM NEW | 14,364 | $11,827 | dollars as filed | |
| JASPER THERAPEUTICS INC | 471871202 | COM NEW | 24,093 | $10,144 | dollars as filed | |
| BIOMX INC | 09090D509 | COM NEW | 19,473 | $6,773 | dollars as filed |
Amendment chain
| Filing | Role | Filed | Accepted | Ingested |
|---|---|---|---|---|
| 13F-HR 0001420506-26-001820 | this filing | 2026-08-14 | acceptance time not in the bulk data set |