GREAT POINT PARTNERS LLC
Follow13F filer, CIK 1281446, Greenwich, CT
GREAT POINT PARTNERS LLC reported $529,120,900 across 42 holdings for the quarter ended 2026-06-30, in a 13F-HR filed 2026-08-14. Its ten largest share positions make up 53.65% of the portfolio.
Filed (acceptance time not in the bulk data set), ingested 13F-HR 0001172661-26-003750
- Period
- 2026-06-30
- Reported value
- $529M
- Holdings
- 42
- Top 10 weight
- 53.65%
- New
- 13
- Sold out
- 13
Largest buys vs the previous quarter
| Security | Shares change | Approx. value |
|---|---|---|
| ABVXnew | +204,314 | $27.2M |
| DFTXnew | +425,000 | $20M |
| VERAadded | +401,488 | $17.2M |
| SGMTnew | +2,029,933 | $15.7M |
| IMMXadded | +927,642 | $9.56M |
Ranked by the share change valued at this quarter's implied price (value over shares in the 13F). A position sold out is valued at the previous quarter's price, its last report.
Largest sells vs the previous quarter
| Security | Shares change | Approx. value |
|---|---|---|
| APGEexited | -374,000 | -$31.5M |
| AMLXreduced | -1,050,000 | -$18.9M |
| KALVexited | -675,000 | -$13.6M |
| IMVTexited | -545,625 | -$13.6M |
| JBIOexited | -964,462 | -$13.6M |
Ranked by the share change valued at this quarter's implied price (value over shares in the 13F). A position sold out is valued at the previous quarter's price, its last report.
Holdings, Q2 2026
Share positions as resolved from 13F-HR 0001172661-26-003750, largest first. % of portfolio is the value over $424,448,729, the sum of the share positions whose value is usable for ratios (method).
| Security | History | Shares | Value | % of portfolio | Change | Latest event | Timeline |
|---|---|---|---|---|---|---|---|
| VORVOR BIOPHARMA INC | 1,700,000 | $31.3M | 7.37% | -50,000 | Timeline | ||
| ABVXABIVAX SA | 204,314 | $27.2M | 6.41% | new | Timeline | ||
| VERAVERA THERAPEUTICS INC | 600,836 | $25.8M | 6.07% | +401,488 | Timeline | ||
| ZURAZURA BIO LTD | 4,215,930 | $24.9M | 5.86% | 0 | Timeline | ||
| ALMSALUMIS INC | 856,061 | $24.1M | 5.68% | 0 | Timeline | ||
| SLGLSOL-GEL TECHNOLOGIES LTD | 274,363 | $20.3M | 4.79% | 0 | Timeline | ||
| DFTXDEFINIUM THERAPEUTICS INC | 425,000 | $20M | 4.71% | new | Timeline | ||
| ANNXANNEXON INC | 3,500,000 | $20M | 4.71% | +1,000,000 | Timeline | ||
| ORKAORUKA THERAPEUTICS INC | 183,330 | $17.4M | 4.11% | 0 | Timeline | ||
| MLTXMOONLAKE IMMUNOTHERAPEUTICS | 855,813 | $16.7M | 3.93% | +355,813 | Timeline | ||
| SGMTSAGIMET BIOSCIENCES INC | 2,029,933 | $15.7M | 3.7% | new | Timeline | ||
| CTNMCONTINEUM THERAPEUTICS INC | 921,481 | $15.1M | 3.56% | +121,283 | Timeline | ||
| IMMXIMMIX BIOPHARMA INC | 1,277,642 | $13.2M | 3.1% | +927,642 | Timeline | ||
| CLYMCLIMB BIO INC | 1,000,000 | $13M | 3.07% | -334,130 | Timeline | ||
| AMLXAMYLYX PHARMACEUTICALS INC | 700,000 | $12.6M | 2.96% | -1,050,000 | Timeline | ||
| NKTRNEKTAR THERAPEUTICS | 175,000 | $12.2M | 2.88% | -141,453 | Timeline | ||
| NGNENEUROGENE INC | 352,180 | $11.1M | 2.61% | -147,820 | Timeline | ||
| LBRXLB PHARMACEUTICALS INC | 317,221 | $10.3M | 2.43% | +17,221 | Timeline | ||
| IRDOPUS GENETICS INC | 1,970,187 | $8.1M | 1.91% | +1,645,847 | Timeline | ||
| EPRXEUPRAXIA PHARMACEUTICALS INC | 1,200,000 | $7.93M | 1.87% | 0 | Timeline | ||
| DRUGBRIGHT MINDS BIOSCIENCES INC | 109,603 | $7.69M | 1.81% | -110,397 | Timeline | ||
| IFRXINFLARX NV | 3,046,557 | $6.82M | 1.61% | new | Timeline | ||
| RLMDRELMADA THERAPEUTICS INC | 842,106 | $5.83M | 1.37% | 0 | Timeline | ||
| JATTJATT II ACQUISITION CORP | 500,000 | $5.68M | 1.34% | new | Timeline | ||
| CGEMCULLINAN THERAPEUTICS INC | 300,000 | $5.46M | 1.29% | 0 | Timeline | ||
| ALTALTIMMUNE INC | 1,741,232 | $5.29M | 1.25% | new | Timeline | ||
| AMANAMANAT ACQUISITION CORP | 500,000 | $5.08M | 1.2% | new | Timeline | ||
| RZLTREZOLUTE INC | 951,809 | $4.95M | 1.17% | 0 | Timeline | ||
| SLNSILENCE THERAPEUTICS PLC | 450,000 | $4.94M | 1.16% | -570,489 | Timeline | ||
| PALIPALISADE BIO INC | 2,284,819 | $4.78M | 1.13% | -1,120,938 | Timeline | ||
| EVMNEVOMMUNE INC | 325,000 | $4.32M | 1.02% | 0 | Timeline | ||
| SCYXSCYNEXIS INC | 944,292 | $3.84M | 0.91% | new | Timeline | ||
| ELVNENLIVEN THERAPEUTICS INC | 70,000 | $3.55M | 0.84% | new | Timeline | ||
| HUMAHUMACYTE INC | 3,750,000 | $2.93M | 0.69% | 0 | Timeline | ||
| RNTXREIN THERAPEUTICS INC | 2,575,000 | $2.68M | 0.63% | new | Timeline | ||
| DBVTDBV TECHNOLOGIES S A | 156,906 | $2.57M | 0.61% | new | Timeline | ||
| PMNPROMIS NEUROSCIENCES INC | 86,150 | $1.13M | 0.27% | -285,252 | Timeline |
Options
Puts and calls, as filed. The amount and value describe the underlying shares, not the option premium, so they stay out of % of portfolio (H5).
Sold out in Q2 2026
Positions in the previous quarter's report that this quarter's report no longer lists.
| Security | Shares before | Value before | Type |
|---|---|---|---|
| APGEAPOGEE THERAPEUTICS INC | 374,000 | $31.5M | shares |
| KALVKALVISTA PHARMACEUTICALS INC | 675,000 | $13.6M | shares |
| IMVTIMMUNOVANT INC | 545,625 | $13.6M | shares |
| JBIOJADE BIOSCIENCES INC | 964,462 | $13.6M | shares |
| ZBIOZENAS BIOPHARMA INC | 524,066 | $10.2M | shares |
| CMPXCOMPASS THERAPEUTICS INC | 1,350,000 | $7.14M | shares |
| SCYXSCYNEXIS INC | 7,554,347 | $6.93M | shares |
| CNTXCONTEXT THERAPEUTICS INC | 2,238,496 | $5.86M | shares |
| UNCYUNICYCIVE THERAPEUTICS INC | 796,558 | $5.24M | shares |
| TENXTENAX THERAPEUTICS INC | 327,307 | $5.23M | shares |
| PHVSPHARVARIS N V | 82,800 | $2.34M | shares |
| AVTXAVALO THERAPEUTICS INC | 124,666 | $1.86M | shares |
| ALKSALKERMES PLC | 50,000 | $1.77M | shares |
How Q2 2026 was built
Available 13F filings of this filer for the quarter and their roles: the base report is the latest original or restatement, NEW HOLDINGS amendments filed after it are added (method).
| Filing | Role | Amendment | Filed | Accepted | Ingested |
|---|---|---|---|---|---|
| 13F-HR 0001172661-26-003750 | base | 2026-08-14 | acceptance time not in the bulk data set |
Filings
Every filing of this filer: 13F reports and notices, the 13D and 13G it filed or is a reporting person of, and Forms 3, 4 and 5 it reported as an owner.
| Filing | Subject | Filed | Accepted | Ingested |
|---|---|---|---|---|
| 13F-HR 0001172661-26-003750 | Quarter ended 2026-06-30 | 2026-08-14 | acceptance time not in the bulk data set | |
| 13F-HR 0001172661-26-002272 | Quarter ended 2026-03-31 | 2026-05-15 | acceptance time not in the bulk data set | |
| 13F-HR 0001172661-26-001093 | Quarter ended 2025-12-31 | 2026-02-17 | acceptance time not in the bulk data set | |
| 13F-HR 0001814554-25-000164 | Quarter ended 2025-09-30 | 2025-11-14 | acceptance time not in the bulk data set | |
| 13F-HR 0001172661-25-003478 | Quarter ended 2025-06-30 | 2025-08-14 | acceptance time not in the bulk data set | |
| 13F-HR 0001172661-25-002331 | Quarter ended 2025-03-31 | 2025-05-15 | acceptance time not in the bulk data set | |
| 13F-HR 0001172661-25-001157 | Quarter ended 2024-12-31 | 2025-02-14 | acceptance time not in the bulk data set | |
| 13F-HR 0001172661-24-004656 | Quarter ended 2024-09-30 | 2024-11-13 | acceptance time not in the bulk data set | |
| 13F-HR 0001172661-24-003577 | Quarter ended 2024-06-30 | 2024-08-14 | acceptance time not in the bulk data set | |
| 13F-HR 0001172661-24-002523 | Quarter ended 2024-03-31 | 2024-05-15 | acceptance time not in the bulk data set | |
| 13F-HR 0001172661-24-001436 | Quarter ended 2023-12-31 | 2024-02-14 | acceptance time not in the bulk data set | |
| 13F-HR 0001172661-23-004025 | Quarter ended 2023-09-30 | 2023-11-14 | acceptance time not in the bulk data set | |
| 13F-HR 0001172661-23-003165 | Quarter ended 2023-06-30 | 2023-08-14 | acceptance time not in the bulk data set | |
| 13F-HR 0001172661-23-002293 | Quarter ended 2023-03-31 | 2023-05-15 | acceptance time not in the bulk data set | |
| 13F-HR 0001172661-23-001300 | Quarter ended 2022-12-31 | 2023-02-14 | acceptance time not in the bulk data set | |
| 13F-HR 0001172661-22-002573 | Quarter ended 2022-09-30 | 2022-11-14 | acceptance time not in the bulk data set | |
| 13F-HR 0001172661-22-001993 | Quarter ended 2022-06-30 | 2022-08-15 | acceptance time not in the bulk data set | |
| 13F-HR 0001172661-22-001465 | Quarter ended 2022-03-31 | 2022-05-16 | acceptance time not in the bulk data set | |
| 13F-HR 0001172661-22-000487 | Quarter ended 2021-12-31 | 2022-02-14 | acceptance time not in the bulk data set | |
| 13F-HR 0001172661-21-002382 | Quarter ended 2021-09-30 | 2021-11-15 | acceptance time not in the bulk data set | |
| 13F-HR 0001172661-21-001868 | Quarter ended 2021-06-30 | 2021-08-16 | acceptance time not in the bulk data set | |
| 13F-HR 0001172661-21-001313 | Quarter ended 2021-03-31 | 2021-05-17 | acceptance time not in the bulk data set | |
| 13F-HR 0001172661-21-000726 | Quarter ended 2020-12-31 | 2021-02-16 | acceptance time not in the bulk data set | |
| 13F-HR 0001172661-20-002326 | Quarter ended 2020-09-30 | 2020-11-16 | acceptance time not in the bulk data set | |
| 13F-HR 0001172661-20-001861 | Quarter ended 2020-06-30 | 2020-08-14 | acceptance time not in the bulk data set | |
| 13F-HR 0001172661-20-001361 | Quarter ended 2020-03-31 | 2020-05-15 | acceptance time not in the bulk data set | |
| 13F-HR 0001172661-20-000830 | Quarter ended 2019-12-31 | 2020-02-14 | acceptance time not in the bulk data set | |
| 13F-HR 0000930413-19-002849 | Quarter ended 2019-09-30 | 2019-11-15 | acceptance time not in the bulk data set | |
| 13F-HR 0000930413-19-002313 | Quarter ended 2019-06-30 | 2019-08-14 | acceptance time not in the bulk data set | |
| 13F-HR 0000930413-19-001676 | Quarter ended 2019-03-31 | 2019-05-14 | acceptance time not in the bulk data set | |
| 13F-HR 0000930413-19-000592 | Quarter ended 2018-12-31 | 2019-02-15 | acceptance time not in the bulk data set | |
| 13F-HR 0000930413-18-003323 | Quarter ended 2018-09-30 | 2018-11-14 | acceptance time not in the bulk data set | |
| 13F-HR 0000930413-18-002592 | Quarter ended 2018-06-30 | 2018-08-14 | acceptance time not in the bulk data set | |
| 13F-HR 0000930413-18-001815 | Quarter ended 2018-03-31 | 2018-05-14 | acceptance time not in the bulk data set | |
| 13F-HR 0000930413-18-000474 | Quarter ended 2017-12-31 | 2018-02-14 | acceptance time not in the bulk data set | |
| 13F-HR 0000930413-17-003778 | Quarter ended 2017-09-30 | 2017-11-14 | acceptance time not in the bulk data set | |
| 13F-HR 0000930413-17-002918 | Quarter ended 2017-06-30 | 2017-08-14 | acceptance time not in the bulk data set | |
| 13F-HR 0000930413-17-002121 | Quarter ended 2017-03-31 | 2017-05-15 | acceptance time not in the bulk data set | |
| 13F-HR 0000930413-17-000546 | Quarter ended 2016-12-31 | 2017-02-14 | acceptance time not in the bulk data set | |
| 13F-HR 0000930413-16-008703 | Quarter ended 2016-09-30 | 2016-11-14 | acceptance time not in the bulk data set | |
| 13F-HR 0000930413-16-007885 | Quarter ended 2016-06-30 | 2016-08-15 | acceptance time not in the bulk data set | |
| 13F-HR 0000930413-16-007144 | Quarter ended 2016-03-31 | 2016-05-16 | acceptance time not in the bulk data set | |
| 13F-HR 0000930413-16-005528 | Quarter ended 2015-12-31 | 2016-02-16 | acceptance time not in the bulk data set | |
| 13F-HR 0000930413-15-004329 | Quarter ended 2015-09-30 | 2015-11-16 | acceptance time not in the bulk data set | |
| 13F-HR 0000930413-15-003355 | Quarter ended 2015-06-30 | 2015-08-14 | acceptance time not in the bulk data set | |
| 13F-HR 0000930413-15-002517 | Quarter ended 2015-03-31 | 2015-05-15 | acceptance time not in the bulk data set | |
| 13F-HR 0000930413-15-000640 | Quarter ended 2014-12-31 | 2015-02-17 | acceptance time not in the bulk data set | |
| 13F-HR 0000930413-14-004572 | Quarter ended 2014-09-30 | 2014-11-14 | acceptance time not in the bulk data set | |
| 13F-HR 0000930413-14-003671 | Quarter ended 2014-06-30 | 2014-08-14 | acceptance time not in the bulk data set | |
| 13F-HR 0000930413-14-002534 | Quarter ended 2014-03-31 | 2014-05-15 | acceptance time not in the bulk data set | |
| 13F-HR 0000930413-14-000601 | Quarter ended 2013-12-31 | 2014-02-14 | acceptance time not in the bulk data set | |
| 13F-HR 0000930413-13-005397 | Quarter ended 2013-09-30 | 2013-11-14 | acceptance time not in the bulk data set | |
| 13F-NT 0000930413-13-004245 | Quarter ended 2013-06-30 | 2013-08-14 | acceptance time not in the bulk data set |