13F-HR filed by Rock Springs Capital Management LP
Rock Springs Capital Management LP filed this 13F-HR for the quarter ended 2026-06-30, filed 2026-08-14, with 104 holding rows worth $2,048,808,191.
- Accession
- 0001172661-26-003527
- Filer
- CIK 1595725
- Filed
- 2026-08-14
- Accepted by EDGAR
- acceptance time not in the bulk data set
- Ingested
- Source
- SEC quarterly data set
13F report for Q2 2026
A holdings report, 104 entries on the cover page, a total value of $2,048,808,191 stated on the cover page (in dollars after the unit check, H1), rows summing to $2,048,808,191 with VALUE read as dollars as filed, 13F file number 028-16048. The quarter's positions are built on this report. The resolved quarter.
The information table after summing rows of one CUSIP and put or call (H4), with the CUSIP and issuer name as filed. Values in dollars after the unit check (method).
| Issuer as filed | CUSIP | Class | Amount | Value | Value read as | Type |
|---|---|---|---|---|---|---|
| REVOLUTION MEDICINES INC COM | 76155X100 | Stock | 1,105,210 | $206,983,729 | dollars as filed | |
| TRAVERE THERAPEUTICS INC | 89422G107 | COM | 2,179,069 | $123,792,910 | dollars as filed | |
| Eli Lilly and Company | 532457108 | COM | 98,700 | $118,383,741 | dollars as filed | |
| MADRIGAL PHARMACEUTICALS INC COM | 558868105 | Stock | 174,999 | $93,965,713 | dollars as filed | |
| MIRUM PHARMACEUTICALS INC | 604749101 | COM | 798,145 | $93,438,835 | dollars as filed | |
| RHYTHM PHARMACEUTICALS INC | 76243J105 | COM | 692,598 | $76,899,156 | dollars as filed | |
| KYMERA THERAPEUTICS INC | 501575104 | COM | 453,156 | $51,963,399 | dollars as filed | |
| ARGENX SE SPONSORED ADR | 04016X101 | ADR | 52,750 | $48,939,868 | dollars as filed | |
| ASCENDIS PHARMA A/S | K08588103 | ORD SHS *A* | 168,750 | $45,009,000 | dollars as filed | |
| XENON PHARMACEUTICALS INC COM | 98420N105 | Stock | 683,907 | $41,280,627 | dollars as filed | |
| SCHOLAR ROCK HLDG CORP | 80706P103 | COM | 715,452 | $39,349,860 | dollars as filed | |
| INSMED INC COM PAR $.01 | 457669307 | Stock | 362,150 | $38,612,433 | dollars as filed | |
| PENUMBRA INC COM | 70975L107 | Stock | 115,750 | $36,548,063 | dollars as filed | |
| STRUCTURE THERAPEUTICS INC COMP | 86366E106 | EQUITY | 640,317 | $34,365,813 | dollars as filed | |
| ULTRAGENYX PHARMACEUTICAL IN | 90400D108 | COM | 967,855 | $32,316,678 | dollars as filed | |
| IRHYTHM HOLDINGS INC COM | 450056106 | Stock | 269,650 | $32,074,868 | dollars as filed | |
| Intuitive Surgical,Inc. | 46120E602 | COM | 76,460 | $30,406,613 | dollars as filed | |
| AGILON HEALTH INC | 00857U206 | COMMON STOCK | 262,600 | $28,145,468 | dollars as filed | |
| UnitedHealth Group Inc | 91324P102 | COM | 63,750 | $26,496,413 | dollars as filed | |
| CELLDEX THERAPEUTICS INC NEW | 15117B202 | COM NEW | 699,146 | $26,015,223 | dollars as filed | |
| ERASCA INC COM | 29479A108 | Stock | 1,402,150 | $25,687,388 | dollars as filed | |
| NEUROCRINE BIOSCIENCES INC | 64125C109 | COM | 144,750 | $24,395,441 | dollars as filed | |
| ENLIVEN THERAPEUTICS INC COM | 29337E102 | Stock | 464,625 | $23,579,719 | dollars as filed | |
| TENET HEALTHCARE CORP COM NEW | 88033G407 | Stock | 125,000 | $23,385,000 | dollars as filed | |
| DEXCOM INC COM | 252131107 | Stock | 343,000 | $23,101,050 | dollars as filed | |
| ACLARIS THERAPEUTICS INC COM | 00461U105 | Stock | 4,330,532 | $22,908,514 | dollars as filed | |
| MINIMED GROUP INC | 60365F109 | COMMON STOCK | 1,520,000 | $22,724,000 | dollars as filed | |
| Boston Scientific Corporation | 101137107 | COM | 528,500 | $22,556,380 | dollars as filed | |
| PHARVARIS NV | N69605108 | COMMON STOCK | 648,333 | $22,419,355 | dollars as filed | |
| AVALYN PHARMA INC | 05348Y105 | COMMON STOCK | 662,918 | $21,823,261 | dollars as filed | |
| HEMAB THERAPEUTICS HLDGS INC | 423494103 | COM SHS | 575,432 | $21,135,617 | dollars as filed | |
| DYNE THERAPEUTICS INC COM | 26818M108 | Stock | 942,154 | $20,925,240 | dollars as filed | |
| ALNYLAM PHARMACEUTICALS INC COM | 02043Q107 | Stock | 66,750 | $20,093,753 | dollars as filed | |
| COGENT BIOSCIENCES INC | 19240Q201 | COM | 515,917 | $19,965,988 | dollars as filed | |
| AGIOS PHARMACEUTICALS INC | 00847X104 | COM | 532,563 | $19,763,413 | dollars as filed | |
| NEWAMSTERDAM PHARMA CO NV | N62509109 | COMMON STOCK | 582,744 | $19,749,194 | dollars as filed | |
| VERA THERAPEUTICS INC | 92337R101 | COMMON STOCK | 427,584 | $18,347,629 | dollars as filed | |
| TARSUS PHARMACEUTICALS INC | 87650L103 | COMMON STOCK | 277,087 | $17,439,856 | dollars as filed | |
| HEARTFLOW INC | 42238D107 | COM | 573,500 | $16,826,490 | dollars as filed | |
| MBX BIOSCIENCES INC COM | 55287L101 | Stock | 298,218 | $16,461,634 | dollars as filed | |
| CYTOKINETICS INC | 23282W605 | COM NEW | 187,980 | $16,014,016 | dollars as filed | |
| BICARA THERAPEUTICS INC | 055477103 | COM | 535,286 | $15,892,641 | dollars as filed | |
| PARABILIS MEDICINES INC COM | 698955101 | Stock | 578,028 | $15,820,626 | dollars as filed | |
| ZAI LAB LTD ADR | 98887Q104 | ADR | 814,707 | $15,479,433 | dollars as filed | |
| Danaher Corporation | 235851102 | COM | 76,300 | $14,533,624 | dollars as filed | |
| TANGO THERAPEUTICS INC | 87583X109 | COM | 456,551 | $14,271,784 | dollars as filed | |
| EVOLENT HEALTH INC CL A | 30050B101 | Stock | 2,500,000 | $13,550,000 | dollars as filed | |
| PTC THERAPEUTICS INC | 69366J200 | COM | 162,298 | $13,238,648 | dollars as filed | |
| MINERALYS THERAPEUTICS INC | 603170101 | COM | 484,951 | $13,083,978 | dollars as filed | |
| ZENAS BIOPHARMA INC COM | 98937L105 | Stock | 502,077 | $12,742,714 | dollars as filed | |
| ARDELYX INC | 039697107 | COM | 2,241,769 | $11,433,022 | dollars as filed | |
| INSPIRE MED SYS INC COM | 457730109 | Stock | 244,000 | $10,884,840 | dollars as filed | |
| BRIDGEBIO PHARMA INC | 10806X102 | COM | 144,750 | $10,780,980 | dollars as filed | |
| ALKERMES PLC | G01767105 | SHS | 199,811 | $10,469,097 | dollars as filed | |
| SUMMIT THERAPEUTICS INC | 86627T108 | COM | 715,000 | $10,417,550 | dollars as filed | |
| AZENTA INC | 114340102 | COM | 403,000 | $10,284,560 | dollars as filed | |
| INDIVIOR PHARMACEUTICALS INC | 45579U109 | COM | 245,500 | $10,072,865 | dollars as filed | |
| Stryker Corporation | 863667101 | COM | 29,000 | $9,130,360 | dollars as filed | |
| AMYLYX PHARMACEUTICALS INC | 03237H101 | COM | 499,764 | $8,975,761 | dollars as filed | |
| CARIS LIFE SCIENCES INC | 142152107 | COMMON STOCK | 487,500 | $8,687,250 | dollars as filed | |
| OMADA HEALTH INC | 68170A108 | COM | 373,000 | $8,187,350 | dollars as filed | |
| COMPASS THERAPEUTICS INC | 20454B104 | COM | 3,524,929 | $7,719,595 | dollars as filed | |
| IMMUNOME INC | 45257U108 | COM | 347,666 | $7,367,043 | dollars as filed | |
| EDAP TMS S A | 268311107 | SPONSORED ADR | 1,386,000 | $7,179,480 | dollars as filed | |
| PHREESIA INC | 71944F106 | COM | 696,900 | $7,171,101 | dollars as filed | |
| OMEROS CORP | 682143102 | COM | 718,499 | $6,832,925 | dollars as filed | |
| DEFINIUM THERAPEUTICS INC | 24477V105 | COM SHS | 143,187 | $6,735,516 | dollars as filed | |
| CORCEPT THERAPEUTICS INC | 218352102 | COM | 72,000 | $6,260,400 | dollars as filed | |
| JANUX THERAPEUTICS INC | 47103J105 | COM | 367,009 | $5,637,258 | dollars as filed | |
| MOBIA MED INC | 60705V103 | COMMON STOCK | 418,200 | $5,603,880 | dollars as filed | |
| ARCUS BIOSCIENCES INC | 03969F109 | COM | 180,000 | $5,549,400 | dollars as filed | |
| Thermo Fisher Scientific Inc. | 883556102 | COM | 10,000 | $5,013,600 | dollars as filed | |
| TREVI THERAPEUTICS INC COM | 89532M101 | Stock | 260,000 | $4,849,000 | dollars as filed | |
| SIONNA THERAPEUTICS INC | 829401108 | COMMON STOCK | 99,429 | $4,373,882 | dollars as filed | |
| CVS Health Corporation | 126650100 | COM | 40,000 | $4,138,000 | dollars as filed | |
| EYEPOINT INC COM NEW | 30233G209 | Stock | 268,519 | $3,839,822 | dollars as filed | |
| OCULAR THERAPEUTIX INC | 67576A100 | COM | 383,716 | $3,768,091 | dollars as filed | |
| SPYRE THERAPEUTICS INC | 00773J202 | COM NEW | 42,254 | $3,751,310 | dollars as filed | |
| TALPHERA INC | 00444T209 | COM NEW | 3,589,186 | $3,696,862 | dollars as filed | |
| ROIVANT SCIENCES LTD | G76279101 | SHS | 101,000 | $3,574,390 | dollars as filed | |
| VAXCYTE INC COM | 92243G108 | Stock | 60,250 | $3,502,333 | dollars as filed | |
| NEUROGENE INC | 64135M105 | COMMON STOCK | 106,750 | $3,357,288 | dollars as filed | |
| CENTURY THERAPEUTICS INC | 15673T100 | COM | 1,304,347 | $3,195,650 | dollars as filed | |
| ALPHATEC HLDGS INC | 02081G201 | COM NEW | 360,000 | $3,114,000 | dollars as filed | |
| NOVO-NORDISK A S ADR | 670100205 | ADR | 63,500 | $3,044,190 | dollars as filed | |
| OLEMA PHARMACEUTICALS INC | 68062P106 | COM | 235,178 | $2,942,077 | dollars as filed | |
| NERVGEN PHARMA CORP | 64082X203 | COM | 1,208,231 | $2,488,956 | dollars as filed | |
| Medtronic Plc | G5960L103 | COM | 30,900 | $2,417,307 | dollars as filed | |
| TEVA PHARMACEUTICAL INDS LTD SPONSORED ADS | 881624209 | ADR | 59,000 | $1,998,920 | dollars as filed | |
| DIANTHUS THERAPEUTICS INC | 252828108 | COM | 20,326 | $1,981,378 | dollars as filed | |
| SAGIMET BIOSCIENCES INC A | 786700104 | COMMON STOCK | 250,000 | $1,932,500 | dollars as filed | |
| CAPRICOR THERAPEUTICS INC | 14070B309 | COMMON STOCK | 74,448 | $1,792,708 | dollars as filed | |
| LENZ THERAPEUTICS INC | 52635N103 | COM | 257,460 | $1,462,373 | dollars as filed | |
| ALTIMMUNE INC | 02155H200 | COM NEW | 471,465 | $1,433,254 | dollars as filed | |
| KAILERA THERAPEUTICS INC | 482931102 | COMMON STOCK | 65,000 | $1,431,950 | dollars as filed | |
| SURGERY PARTNERS INC | 86881A100 | COM | 84,000 | $1,411,200 | dollars as filed | |
| AXSOME THERAPEUTICS INC. COM | 05464T104 | Stock | 5,500 | $1,346,235 | dollars as filed | |
| ORUKA THERAPEUTICS INC COM | 687604108 | Stock | 12,051 | $1,146,894 | dollars as filed | |
| VIKING THERAPEUTICS INC | 92686J106 | COM | 25,500 | $994,755 | dollars as filed | |
| LEGEND BIOTECH CORP | 52490G102 | SPONSORED ADS | 33,500 | $967,480 | dollars as filed | |
| GLAUKOS CORP COM | 377322102 | Stock | 4,750 | $663,860 | dollars as filed | |
| JASPER THERAPEUTICS INC | 471871202 | COM NEW | 1,100,726 | $463,406 | dollars as filed | |
| BIOCRYST PHARMACEUTICALS INC COM | 09058V103 | Stock | 22,124 | $221,240 | dollars as filed | |
| MOONLAKE IMMUNOTHERAPEUTICS CLASS A ORD | 61559X104 | Stock | 10,696 | $208,251 | dollars as filed |
Amendment chain
| Filing | Role | Filed | Accepted | Ingested |
|---|---|---|---|---|
| 13F-HR 0001172661-26-003527 | this filing | 2026-08-14 | acceptance time not in the bulk data set |