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ORBIMED ADVISORS LLC

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13F filer, CIK 1055951, New York, NY

ORBIMED ADVISORS LLC reported $4,899,391,958 across 107 holdings for the quarter ended 2025-12-31, in a 13F-HR filed 2026-02-17. Its ten largest share positions make up 40.48% of the portfolio.

Filed (acceptance time not in the bulk data set), ingested 13F-HR 0001172661-26-001119

Period
2025-12-31
Reported value
$4.9B
Holdings
107
Top 10 weight
40.48%
New
25
Sold out
27

Part of the filer group ORBIMED ADVISORS LLC

How groups are built

Stakes and trades reported after 2025-12-31

13D, 13G and Form 4 filings by this filer's group, dated after the 13F period, on securities the quarter does not hold as shares.

  • ADARX PHARMACEUTICALS INC: 13D 14,913,764 shares, 14% of the class, 13D filed 2026-10-02, 0000947871-26-000917
    Accepted , ingested
  • ELECTRA THERAPEUTICS INC: 13D 6,885,170 shares, 11% of the class, 13D filed 2026-09-25, 0000947871-26-000898
    Accepted , ingested

Largest buys vs the previous quarter

SecurityShares changeApprox. value
BMYnew+775,000$41.8M
PFEnew+1,652,900$41.2M
ELVnew+99,100$34.7M
HELPnew+3,840,500$31.4M
PRAXnew+94,500$27.9M

Ranked by the share change valued at this quarter's implied price (value over shares in the 13F). A position sold out is valued at the previous quarter's price, its last report.

Largest sells vs the previous quarter

SecurityShares changeApprox. value
TERNreduced-5,409,671-$219M
RNAMreduced-1,019,356-$73.5M
EXASreduced-642,900-$65.3M
AXSMreduced-278,679-$50.9M
SIBNexited-2,578,979-$38M

Ranked by the share change valued at this quarter's implied price (value over shares in the 13F). A position sold out is valued at the previous quarter's price, its last report.

Holdings, Q4 2025

Share positions as resolved from 13F-HR 0001172661-26-001119, largest first. % of portfolio is the value over $4,886,574,540, the sum of the share positions whose value is usable for ratios (method).

SecurityHistorySharesValue% of portfolioChangeLatest eventTimeline
EWTXEDGEWISE THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 15,021,721 shares; 2024Q4: 15,021,721 shares; 2025Q1: 15,021,721 shares; 2025Q2: 15,518,492 shares; 2025Q3: 15,518,492 shares; 2025Q4: 15,518,492 shares 15,518,492$385M7.88%0Timeline
LLYELI LILLY & COQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 337,600 shares; 2024Q4: 337,600 shares; 2025Q1: 337,600 shares; 2025Q2: 337,600 shares; 2025Q3: 301,200 shares; 2025Q4: 301,200 shares 301,200$324M6.62%0Timeline
BSXBOSTON SCIENTIFIC CORPQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 3,273,000 shares; 2024Q4: 3,160,300 shares; 2025Q1: 2,813,200 shares; 2025Q2: 2,813,200 shares; 2025Q3: 2,429,300 shares; 2025Q4: 2,419,300 shares 2,419,300$231M4.72%-10,000Timeline
SVASINOVAC BIOTECH LTDQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 2,718,735 shares; 2024Q4: 2,718,735 shares; 2025Q1: 2,718,735 shares; 2025Q2: 2,718,735 shares; 2025Q3: 2,718,735 shares; 2025Q4: 2,718,735 shares 2,718,735$184M3.77%0Timeline
EWEDWARDS LIFESCIENCES CORPQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: 1,145,302 shares; 2025Q1: 1,532,000 shares; 2025Q2: 1,708,000 shares; 2025Q3: 1,684,000 shares; 2025Q4: 1,842,900 shares 1,842,900$157M3.22%+158,900Timeline
UPBUPSTREAM BIO INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: 5,693,589 shares; 2025Q1: 5,693,589 shares; 2025Q2: 5,693,589 shares; 2025Q3: 5,693,589 shares; 2025Q4: 5,693,589 shares 5,693,589$155M3.16%0Timeline
ISRGINTUITIVE SURGICAL INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 433,800 shares; 2024Q4: 401,700 shares; 2025Q1: 291,000 shares; 2025Q2: 291,000 shares; 2025Q3: 287,200 shares; 2025Q4: 263,400 shares 263,400$149M3.05%-23,800Timeline
SIONSIONNA THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: 3,704,959 shares; 2025Q2: 3,704,959 shares; 2025Q3: 3,704,959 shares; 2025Q4: 3,561,655 shares 3,561,655$147M3%-143,304Timeline
MBXMBX BIOSCIENCES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 3,812,215 shares; 2024Q4: 3,812,215 shares; 2025Q1: 4,002,887 shares; 2025Q2: 4,002,887 shares; 2025Q3: 4,002,887 shares; 2025Q4: 3,935,203 shares 3,935,203$124M2.54%-67,684Timeline
ARGXARGENX SEQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 204,500 shares; 2024Q4: 189,700 shares; 2025Q1: 206,700 shares; 2025Q2: 208,000 shares; 2025Q3: 172,300 shares; 2025Q4: 146,000 shares 146,000$123M2.51%-26,300Timeline
ELVNENLIVEN THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 7,959,538 shares; 2024Q4: 7,959,538 shares; 2025Q1: 7,959,538 shares; 2025Q2: 7,959,538 shares; 2025Q3: 7,959,538 shares; 2025Q4: 7,959,538 shares 7,959,538$123M2.51%0Timeline
ALNYALNYLAM PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 250,300 shares; 2024Q4: 415,600 shares; 2025Q1: 346,100 shares; 2025Q2: 341,900 shares; 2025Q3: 301,600 shares; 2025Q4: 288,800 shares 288,800$115M2.35%-12,800Timeline
SYKSTRYKER CORPORATIONQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 344,400 shares; 2024Q4: 344,400 shares; 2025Q1: 359,200 shares; 2025Q2: 359,200 shares; 2025Q3: 359,200 shares; 2025Q4: 325,000 shares 325,000$114M2.34%-34,200Timeline
SPRYARS PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 8,288,510 shares; 2024Q4: 8,288,510 shares; 2025Q1: 8,288,510 shares; 2025Q2: 8,288,510 shares; 2025Q3: 8,288,510 shares; 2025Q4: 8,288,510 shares 8,288,510$96.6M1.98%0Timeline
TERNTERNS PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 7,562,971 shares; 2024Q4: 7,562,971 shares; 2025Q1: 7,562,971 shares; 2025Q2: 7,562,971 shares; 2025Q3: 7,562,971 shares; 2025Q4: 2,153,300 shares 2,153,300$87M1.78%-5,409,671Timeline
IRONDISC MEDICINE INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 1,785,571 shares; 2024Q4: 1,785,571 shares; 2025Q1: 1,415,020 shares; 2025Q2: 1,415,020 shares; 2025Q3: 1,415,020 shares; 2025Q4: 1,067,550 shares 1,067,550$84.8M1.73%-347,470Timeline
CAICARIS LIFE SCIENCES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 3,034,858 shares; 2025Q3: 3,034,858 shares; 2025Q4: 3,116,011 shares 3,116,011$84.1M1.72%+81,153Timeline
NTRANATERA INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 687,500 shares; 2024Q4: 413,000 shares; 2025Q1: 547,000 shares; 2025Q2: 593,434 shares; 2025Q3: 429,300 shares; 2025Q4: 365,800 shares 365,800$83.8M1.71%-63,500Timeline
CMPXCOMPASS THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 22,362,850 shares; 2024Q4: 22,362,850 shares; 2025Q1: 22,362,850 shares; 2025Q2: 15,219,994 shares; 2025Q3: 15,219,994 shares; 2025Q4: 15,219,994 shares 15,219,994$81.7M1.67%0Timeline
GPCRSTRUCTURE THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 383,705 shares; 2024Q4: 652,028 shares; 2025Q1: 652,028 shares; 2025Q2: 1,199,300 shares; 2025Q3: 1,139,300 shares; 2025Q4: 1,161,803 shares 1,161,803$80.8M1.65%+22,503Timeline
DHRDANAHER CORP DELQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 263,100 shares; 2025Q4: 299,800 shares 299,800$68.6M1.4%+36,700Timeline
CGONCG ONCOLOGY INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 691,114 shares; 2024Q4: 1,431,114 shares; 2025Q1: 2,471,994 shares; 2025Q2: 1,877,850 shares; 2025Q3: 1,726,850 shares; 2025Q4: 1,516,550 shares 1,516,550$63M1.29%-210,300Timeline
APLSAPELLIS PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 1,270,400 shares; 2024Q4: not reported; 2025Q1: 1,432,300 shares; 2025Q2: 1,482,300 shares; 2025Q3: 2,323,368 shares; 2025Q4: 2,429,868 shares 2,429,868$61M1.25%+106,500Timeline
AVBPARRIVENT BIOPHARMA INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 3,027,328 shares; 2024Q4: 3,027,328 shares; 2025Q1: 3,027,328 shares; 2025Q2: 3,027,328 shares; 2025Q3: 3,027,328 shares; 2025Q4: 3,027,328 shares 3,027,328$60.9M1.25%02026-10-06, 13D/A: 2,875,962 shares, 5.8% of the class, 13D/A filed 2026-10-08 Timeline
CITHE CIGNA GROUPQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 162,800 shares; 2025Q4: 205,000 shares 205,000$56.4M1.15%+42,200Timeline
RAPTRAPT THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 1,641,906 shares; 2025Q3: 1,086,618 shares; 2025Q4: 1,642,891 shares 1,642,891$55.6M1.14%+556,273Timeline
CRVSCORVUS PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 6,943,654 shares; 2024Q4: 6,943,654 shares; 2025Q1: 6,943,654 shares; 2025Q2: 7,165,006 shares; 2025Q3: 7,165,006 shares; 2025Q4: 7,165,006 shares 7,165,006$55.2M1.13%0Timeline
UTHRUNITED THERAPEUTICS CORP DELQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 114,900 shares; 2025Q4: 105,200 shares 105,200$51.3M1.05%-9,700Timeline
ABVXABIVAX SAQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 380,000 shares; 2025Q4: 367,900 shares 367,900$49.6M1.02%-12,100Timeline
ROIVROIVANT SCIENCES LTDQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 2,779,427 shares; 2025Q3: 2,714,798 shares; 2025Q4: 2,190,907 shares 2,190,907$47.5M0.97%-523,891Timeline
CRNXCRINETICS PHARMACEUTICALS INQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 1,050,055 shares; 2024Q4: 999,000 shares; 2025Q1: 999,000 shares; 2025Q2: 1,149,000 shares; 2025Q3: 1,099,000 shares; 2025Q4: 999,000 shares 999,000$46.5M0.95%-100,000Timeline
AXSMAXSOME THERAPEUTICS INC.Quarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: 386,700 shares; 2025Q2: 427,900 shares; 2025Q3: 531,800 shares; 2025Q4: 253,121 shares 253,121$46.2M0.95%-278,679Timeline
EYPTEYEPOINT INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 1,796,000 shares; 2025Q4: 2,468,314 shares 2,468,314$45.1M0.92%+672,314Timeline
RNAMAVIDITY BIOSCIENCES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 1,044,805 shares; 2024Q4: 1,112,886 shares; 2025Q1: 1,812,886 shares; 2025Q2: 1,812,886 shares; 2025Q3: 1,638,886 shares; 2025Q4: 619,530 shares 619,530$44.7M0.91%-1,019,356Timeline
NBIXNEUROCRINE BIOSCIENCES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 302,220 shares; 2024Q4: 938,120 shares; 2025Q1: 934,640 shares; 2025Q2: 438,540 shares; 2025Q3: 353,640 shares; 2025Q4: 314,240 shares 314,240$44.6M0.91%-39,400Timeline
DYNDYNE THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 708,400 shares; 2024Q4: 1,227,080 shares; 2025Q1: 1,014,611 shares; 2025Q2: 1,031,400 shares; 2025Q3: 2,314,184 shares; 2025Q4: 2,202,184 shares 2,202,184$43.1M0.88%-112,000Timeline
BMYBRISTOL-MYERS SQUIBB COQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 775,000 shares 775,000$41.8M0.86%newTimeline
PFEPFIZER INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: 3,850,200 shares; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 1,652,900 shares 1,652,900$41.2M0.84%newTimeline
TRVITREVI THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: 1,120,000 shares; 2025Q2: 3,308,400 shares; 2025Q3: 3,308,400 shares; 2025Q4: 3,190,700 shares 3,190,700$39.9M0.82%-117,700Timeline
NPCENEUROPACE INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 3,406,335 shares; 2024Q4: 3,406,335 shares; 2025Q1: 3,406,335 shares; 2025Q2: 2,614,184 shares; 2025Q3: 2,614,184 shares; 2025Q4: 2,406,335 shares 2,406,335$37.2M0.76%-207,849Timeline
ASNDASCENDIS PHARMA A/SQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 34,400 shares; 2025Q3: 191,905 shares; 2025Q4: 171,977 shares 171,977$36.7M0.75%-19,928Timeline
EXASEXACT SCIENCES CORPQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 679,816 shares; 2024Q4: 679,816 shares; 2025Q1: 679,816 shares; 2025Q2: 607,316 shares; 2025Q3: 994,616 shares; 2025Q4: 351,716 shares 351,716$35.7M0.73%-642,900Timeline
MLYSMINERALYS THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 2,002,939 shares; 2024Q4: 1,611,637 shares; 2025Q1: not reported; 2025Q2: 760,351 shares; 2025Q3: 1,469,494 shares; 2025Q4: 980,400 shares 980,400$35.6M0.73%-489,094Timeline
ELVELEVANCE HEALTH INC FORMERLYQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 106,200 shares; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 99,100 shares 99,100$34.7M0.71%newTimeline
FBRXFORTE BIOSCIENCES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: 600,000 shares; 2025Q1: 593,088 shares; 2025Q2: 1,196,955 shares; 2025Q3: 1,196,955 shares; 2025Q4: 1,196,955 shares 1,196,955$32.6M0.67%0Timeline
PRLDPRELUDE THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 10,909,256 shares; 2024Q4: 10,909,256 shares; 2025Q1: 10,909,256 shares; 2025Q2: 10,909,256 shares; 2025Q3: 10,909,256 shares; 2025Q4: 10,909,256 shares 10,909,256$31.6M0.65%0Timeline
HELPCYBIN INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 3,840,500 shares 3,840,500$31.4M0.64%newTimeline
ORICORIC PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: 700,000 shares; 2025Q2: 899,281 shares; 2025Q3: 3,641,756 shares; 2025Q4: 3,641,756 shares 3,641,756$29.8M0.61%0Timeline
KRYSKRYSTAL BIOTECH INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 23,500 shares; 2024Q4: 23,500 shares; 2025Q1: 23,500 shares; 2025Q2: 9,200 shares; 2025Q3: 102,745 shares; 2025Q4: 119,800 shares 119,800$29.5M0.6%+17,055Timeline
PRAXPRAXIS PRECISION MEDICINES IQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 94,500 shares 94,500$27.9M0.57%newTimeline
JANXJANUX THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 1,258,566 shares; 2024Q4: 758,566 shares; 2025Q1: 758,566 shares; 2025Q2: 1,210,300 shares; 2025Q3: 1,766,100 shares; 2025Q4: 1,954,426 shares 1,954,426$27M0.55%+188,326Timeline
TMOTHERMO FISHER SCIENTIFIC INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 84,400 shares; 2024Q4: 84,400 shares; 2025Q1: 129,000 shares; 2025Q2: 46,500 shares; 2025Q3: 46,500 shares; 2025Q4: 46,500 shares 46,500$26.9M0.55%0Timeline
BRKRBRUKER CORPQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 555,789 shares 555,789$26.2M0.54%newTimeline
RYTMRHYTHM PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 435,900 shares; 2024Q4: 400,000 shares; 2025Q1: 380,000 shares; 2025Q2: 248,512 shares; 2025Q3: 215,152 shares; 2025Q4: 239,800 shares 239,800$25.7M0.53%+24,648Timeline
STTKSHATTUCK LABS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 6,306,127 shares; 2025Q4: 6,306,127 shares 6,306,127$23M0.47%0Timeline
ESPRESPERION THERAPEUTICS INC NEQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 5,965,498 shares 5,965,498$22.1M0.45%newTimeline
AVTXAVALO THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 967,000 shares; 2024Q4: 967,000 shares; 2025Q1: 967,000 shares; 2025Q2: 967,000 shares; 2025Q3: 1,349,300 shares; 2025Q4: 1,187,300 shares 1,187,300$21.6M0.44%-162,000Timeline
LXEOLEXEO THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 2,125,000 shares 2,125,000$21.1M0.43%newTimeline
ADCTADC THERAPEUTICS SAQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 4,533,801 shares; 2024Q4: 5,968,451 shares; 2025Q1: 5,968,451 shares; 2025Q2: 5,907,351 shares; 2025Q3: 5,907,351 shares; 2025Q4: 5,822,854 shares 5,822,854$20.6M0.42%-84,497Timeline
URGNUROGEN PHARMA LTDQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 478,400 shares; 2025Q3: 689,000 shares; 2025Q4: 875,487 shares 875,487$20.5M0.42%+186,487Timeline
00Quarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 12,048,773 shares; 2024Q4: 12,048,773 shares; 2025Q1: 12,048,773 shares; 2025Q2: 12,048,773 shares; 2025Q3: 6,210,899 shares; 2025Q4: 6,210,899 shares 6,210,899$20.1M0.41%0
XENEXENON PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 911,420 shares; 2024Q4: 947,877 shares; 2025Q1: 947,877 shares; 2025Q2: 947,877 shares; 2025Q3: 419,600 shares; 2025Q4: 447,200 shares 447,200$20M0.41%+27,600Timeline
BTSGBRIGHTSPRING HEALTH SVCS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 263,800 shares; 2025Q4: 488,500 shares 488,500$18.3M0.37%+224,700Timeline
VERAVERA THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 675,872 shares; 2024Q4: 742,572 shares; 2025Q1: 481,065 shares; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 353,500 shares 353,500$17.9M0.37%newTimeline
QUREUNIQURE NVQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 458,500 shares; 2025Q4: 737,400 shares 737,400$17.6M0.36%+278,900Timeline
MIND MEDICINE MINDMED INCMIND MEDICINE MINDMED INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 367,824 shares; 2025Q4: 1,226,700 shares 1,226,700$16.4M0.34%+858,876
KROSKEROS THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 1,018,734 shares; 2024Q4: 1,018,734 shares; 2025Q1: 1,018,734 shares; 2025Q2: 1,018,734 shares; 2025Q3: 1,018,734 shares; 2025Q4: 804,212 shares 804,212$16.4M0.34%-214,522Timeline
CARLCARLSMED INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 1,252,600 shares; 2025Q4: 1,252,600 shares 1,252,600$15.5M0.32%0Timeline
CTMXCYTOMX THERAPEUTICS INC.Quarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 8,461,500 shares; 2025Q3: 8,461,500 shares; 2025Q4: 3,525,650 shares 3,525,650$15M0.31%-4,935,850Timeline
VIRVIR BIOTECHNOLOGY INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 3,573,000 shares; 2024Q4: 3,218,617 shares; 2025Q1: 2,248,249 shares; 2025Q2: 2,380,715 shares; 2025Q3: 2,380,715 shares; 2025Q4: 2,380,715 shares 2,380,715$14.4M0.29%0Timeline
BCRXBIOCRYST PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 901,500 shares; 2025Q4: 1,741,800 shares 1,741,800$13.6M0.28%+840,300Timeline
COGTCOGENT BIOSCIENCES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 371,000 shares 371,000$13.2M0.27%newTimeline
CRBPCORBUS PHARMACEUTICALS HLDGSQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 912,552 shares; 2024Q4: 1,172,287 shares; 2025Q1: 1,172,287 shares; 2025Q2: 1,172,287 shares; 2025Q3: 1,172,287 shares; 2025Q4: 1,597,287 shares 1,597,287$13M0.27%+425,000Timeline
TARSTARSUS PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: 653,743 shares; 2025Q2: 197,900 shares; 2025Q3: 197,900 shares; 2025Q4: 154,400 shares 154,400$12.6M0.26%-43,500Timeline
RLMDRELMADA THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 2,610,600 shares 2,610,600$12.6M0.26%newTimeline
TECXTECTONIC THERAPEUTIC INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 574,600 shares 574,600$12M0.25%newTimeline
ALMSALUMIS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 1,926,423 shares; 2025Q3: 1,926,423 shares; 2025Q4: 1,102,730 shares 1,102,730$10.8M0.22%-823,693Timeline
BIOABIOAGE LABS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 1,423,470 shares; 2024Q4: 921,959 shares; 2025Q1: 921,959 shares; 2025Q2: 921,959 shares; 2025Q3: 790,901 shares; 2025Q4: 790,901 shares 790,901$10.5M0.21%0Timeline
FOLDAMICUS THERAPEUTICQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 570,300 shares; 2024Q4: 2,285,400 shares; 2025Q1: 2,285,400 shares; 2025Q2: 2,285,400 shares; 2025Q3: 1,645,400 shares; 2025Q4: 729,900 shares 729,900$10.4M0.21%-915,500Timeline
WHWKWHITEHAWK THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: 4,166,000 shares; 2025Q2: 4,166,000 shares; 2025Q3: 4,166,000 shares; 2025Q4: 4,166,000 shares 4,166,000$10.1M0.21%0Timeline
ACETADICET BIO INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 1,027,944 shares 1,027,944$8.66M0.18%newTimeline
REPARE THERAPEUTICS INCREPARE THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 3,322,488 shares; 2024Q4: 3,322,488 shares; 2025Q1: 3,322,488 shares; 2025Q2: 3,322,488 shares; 2025Q3: 3,322,488 shares; 2025Q4: 3,322,488 shares 3,322,488$8.64M0.18%0
CELCCELCUITY INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 84,020 shares; 2025Q4: 85,664 shares 85,664$8.54M0.17%+1,644Timeline
JBIOJADE BIOSCIENCES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 531,163 shares; 2025Q3: 531,163 shares; 2025Q4: 531,163 shares 531,163$8.2M0.17%0Timeline
KNSAKINIKSA PHARMACEUTICALS INTLQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 187,199 shares 187,199$7.72M0.16%newTimeline
QTTBQ32 BIO INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 2,252,987 shares; 2024Q4: 2,252,987 shares; 2025Q1: 2,252,987 shares; 2025Q2: 2,252,987 shares; 2025Q3: 2,252,987 shares; 2025Q4: 2,252,987 shares 2,252,987$7.48M0.15%0Timeline
PMVPPMV PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 6,475,291 shares; 2024Q4: 6,475,291 shares; 2025Q1: 6,475,291 shares; 2025Q2: 6,475,291 shares; 2025Q3: 5,975,291 shares; 2025Q4: 4,975,291 shares 4,975,291$6.22M0.13%-1,000,000Timeline
KALVKALVISTA PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 382,400 shares 382,400$6.18M0.13%newTimeline
PHVSPHARVARIS N VQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 205,400 shares 205,400$5.7M0.12%newTimeline
NSPRINSPIREMD INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 2,133,405 shares; 2024Q4: 2,133,405 shares; 2025Q1: 2,133,405 shares; 2025Q2: 2,133,405 shares; 2025Q3: 2,133,405 shares; 2025Q4: 3,133,405 shares 3,133,405$5.58M0.11%+1,000,000Timeline
INSMINSMED INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: 94,559 shares; 2025Q1: 28,659 shares; 2025Q2: 13,459 shares; 2025Q3: 13,459 shares; 2025Q4: 25,400 shares 25,400$4.42M0.09%+11,941Timeline
PALIPALISADE BIO INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 1,871,420 shares 1,871,420$4.4M0.09%newTimeline
BCAXBICARA THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 271,910 shares; 2024Q4: 298,301 shares; 2025Q1: 298,301 shares; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 209,100 shares 209,100$3.52M0.07%newTimeline
CGEMCULLINAN THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 1,070,055 shares; 2024Q4: 1,942,555 shares; 2025Q1: 1,923,855 shares; 2025Q2: 1,923,855 shares; 2025Q3: 1,923,855 shares; 2025Q4: 270,006 shares 270,006$2.79M0.06%-1,653,849Timeline
CCCCC4 THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 4,377,900 shares; 2024Q4: 4,377,900 shares; 2025Q1: 6,830,300 shares; 2025Q2: 6,830,300 shares; 2025Q3: 5,235,146 shares; 2025Q4: 1,404,902 shares 1,404,902$2.68M0.05%-3,830,244Timeline
IMAIMAGENEBIO INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 378,556 shares; 2025Q4: 378,556 shares 378,556$2.61M0.05%0Timeline
ANROALTO NEUROSCIENCE INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: 250,000 shares; 2025Q1: 250,000 shares; 2025Q2: 250,000 shares; 2025Q3: 250,000 shares; 2025Q4: 125,000 shares 125,000$2.23M0.05%-125,000Timeline
RVMDREVOLUTION MEDICINES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 25,900 shares 25,900$2.06M0.04%newTimeline
VTGNVISTAGEN THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 3,060,000 shares; 2025Q4: 3,060,000 shares 3,060,000$2.03M0.04%0Timeline
OCULOCULAR THERAPEUTIX INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 157,300 shares 157,300$1.91M0.04%newTimeline
PTGXPROTAGONIST THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 21,700 shares 21,700$1.9M0.04%newTimeline
PTCTPTC THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 23,200 shares 23,200$1.76M0.04%newTimeline
MPLTMAPLIGHT THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 56,000 shares 56,000$952K0.02%newTimeline
TRAWTRAWS PHARMA INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 605,531 shares; 2024Q4: 605,531 shares; 2025Q1: 605,531 shares; 2025Q2: 605,531 shares; 2025Q3: 605,531 shares; 2025Q4: 605,531 shares 605,531$684K0.01%0Timeline

Options

Puts and calls, as filed. The amount and value describe the underlying shares, not the option premium, so they stay out of % of portfolio (H5).

SecurityTypeAmountValueChange
EWEDWARDS LIFESCIENCES CORP Stockcall150,000$12.8Mnew
VTGNVISTAGEN THERAPEUTICS INC COMcall45,200$29.9K0

Principal amounts

Notes and convertibles filed as a face amount (PRN). A face amount is never added to a share count (H6).

SecurityTypeAmountValueChange
COGENT BIOSCIENCES INCCOGENT BIOSCIENCES INC NOTE 1.625%11/1principal1,000,000$1.17Mnew

Sold out in Q4 2025

Positions in the previous quarter's report that this quarter's report no longer lists.

SecurityShares beforeValue beforeType
SIBNSI BONE INC2,578,979$38Mshares
SCPHARMACEUTICALS INCSCPHARMACEUTICALS INC6,059,528$34.4Mshares
ITGRINTEGER HLDGS CORP290,000$30Mshares
AKROAKERO THERAPEUTICS INC526,200$25Mshares
ABTABBOTT LABORATORIES150,000$20.1Mcall
BSXBOSTON SCIENTIFIC CORP200,000$19.5Mcall
PFEPFIZER INC500,000$12.7Mcall
AZNASTRAZENECA PLC-SPONS ADR150,000$11.5Mcall
AMLXAMYLYX PHARMACEUTICALS INC750,600$10.2Mshares
ADICET BIO INCADICET BIO INC11,447,140$9.27Mshares
VSTMVERASTEM INC887,561$7.84Mshares
MISTMILESTONE PHARMACEUTICALS IN3,221,828$6.44Mshares
APLSAPELLIS PHARMACEUTICALS INC250,000$5.66Mcall
BTSGBRIGHTSPRING HEALTH SVCS INC150,000$4.43Mcall
CRNXCRINETICS PHARMACEUTICALS IN100,000$4.17Mput
IMTXIMMATICS N.V466,601$3.98Mshares
SRRKSCHOLAR ROCK HLDG CORP100,000$3.72Mcall
TGTXTG THERAPEUTICS INC100,000$3.61Mcall
CELCUITY INCCELCUITY INC2,000,000$2.68Mprincipal
ATAIBECKLEY INCATAIBECKLEY INC347,000$1.84Mshares
KRROKORRO BIO INC32,400$1.55Mshares
MURAL ONCOLOGY PUB LTD COMURAL ONCOLOGY PUB LTD CO588,800$1.22Mshares
LYELLYELL IMMUNOPHARMA INC51,727$840Kshares
KZRKEZAR LIFE SCIENCES INC192,700$752Kshares
XERSXERIS BIOPHARMA HOLDINGS INC80,420$655Kshares
PASGPASSAGE BIO INC59,046$474Kshares
DIH HLDG US INCDIH HLDG US INC1,915,000$358Kshares

How Q4 2025 was built

Available 13F filings of this filer for the quarter and their roles: the base report is the latest original or restatement, NEW HOLDINGS amendments filed after it are added (method).

FilingRoleAmendmentFiledAcceptedIngested
13F-HR 0001172661-26-001119 base2026-02-17acceptance time not in the bulk data set