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Disclosery

PYXS PYXIS ONCOLOGY INC

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Stock (common), issuer CIK 1782223

74 managers (76 13F filers) reported a position in PYXS shares at 2026-06-30, 34,152,124 shares in all. 9 filers opened a position and 10 filers sold out during the quarter.

Managers
74
13F filers
76
New
9
Added
24
Reduced
24
Sold out
10
Shares held by filers
34,152,124

Shares held by filers adds up every 13F filer's report, so a share reported by a parent and by its subsidiary counts twice (H9). Managers counts each filer group once.

13D and 13G filers

Each filer's latest stake. The shares are the aggregate the reporting persons state, which can include entities that file no 13F.

Insider trades

No Form 4 transaction on this security in the data.

13F holders, Q2 2026

Filers in the available 13F reports with a share position at 2026-06-30, filer groups collapsed to one row (method), largest first. Options and principal amounts are left out. A group row states no % of portfolio, since each member reports its own portfolio: the members' percents are listed under it. A value about 1,000 times or 1/1,000 of the price other filers imply is shown as filed but neither ranks the row nor enters a sum.

HolderSharesValue% of portfolioChangeSource
GordonMD Global Investments LPin group GordonMD Global Investments LP10,024,909$30.2M14.6%+5,903,03913F-HRTimelineGroup
Pfizer Inc7,032,770$19.5M11.43%013F-HRTimeline
Laurion Capital Management LP4,900,888$14.8M1.07%-96,44513F-HRTimeline
VANGUARD GROUP INCgroup of 3 filers holding2,400,225$7.22M+44,576Timeline
Atle Fund Management AB966,459$2.91M0.78%+769,42313F-HRTimeline
BlackRock, Inc.in group BlackRock, Inc.867,934$2.61M<0.01%+79,09513F-HRTimelineGroup
Palo Alto Investors LP864,277$2.6M0.36%-146,23313F-HR/ATimeline
MARSHALL WACE, LLPin group MARSHALL WACE, LLP830,544$2.5M<0.01%+476,12713F-HRTimelineGroup
RENAISSANCE TECHNOLOGIES LLC772,232$2.32M<0.01%-116,44813F-HRTimeline
GEODE CAPITAL MANAGEMENT, LLCin group GEODE CAPITAL MANAGEMENT, LLC591,849$1.78M<0.01%-6,27213F-HRTimelineGroup
Woodline Partners LP523,999$1.58M<0.01%new13F-HRTimeline
683 Capital Management, LLCin group 683 Capital Management, LLC459,367$1.38M0.13%-436,89613F-HRTimelineGroup
JACOBS LEVY EQUITY MANAGEMENT, INC428,606$1.29M<0.01%-32,39113F-HRTimeline
Longaeva Partners L.P.353,582$1.06M0.03%-149,63213F-HRTimeline
Decheng Capital LLC326,810$984K0.13%013F-HRTimeline
JANE STREET GROUP, LLCin group JANE STREET GROUP, LLC290,090$873K<0.01%-14,36913F-HRTimelineGroup
STATE STREET CORPin group STATE STREET CORP248,837$749K<0.01%013F-HRTimelineGroup
MILLENNIUM MANAGEMENT LLCin group MILLENNIUM MANAGEMENT LLC233,004$701K<0.01%-164,62113F-HRTimelineGroup
UBS Group AGin group UBS Group AG155,217$467K<0.01%-98,90713F-HRTimelineGroup
Bank of New York Mellon Corpin group Bank of New York Mellon Corp133,996$403K<0.01%013F-HRTimelineGroup
ACADIAN ASSET MANAGEMENT LLCin group ACADIAN ASSET MANAGEMENT LLC126,793$380K<0.01%-17,46313F-HRTimelineGroup
NORTHERN TRUST CORPin group NORTHERN TRUST CORP123,959$373K<0.01%+22,01113F-HRTimelineGroup
NewEdge Wealth, LLC116,006$349K<0.01%013F-HRTimeline
XTX Topco Ltdin group XTX Topco Ltd110,939$334K<0.01%-89,15713F-HRTimelineGroup
TWO SIGMA INVESTMENTS, LPin group TWO SIGMA INVESTMENTS, LP83,961$253K<0.01%+10,66113F-HRTimelineGroup
BRIDGEWAY CAPITAL MANAGEMENT, LLC81,260$245K<0.01%013F-HRTimeline
BANK OF AMERICA CORP /DE/in group BANK OF AMERICA CORP /DE/80,464$242K<0.01%+63,65713F-HRTimelineGroup
STIFEL FINANCIAL CORPin group STIFEL FINANCIAL CORP70,437$212K<0.01%+19,90013F-HRTimelineGroup
Cable Car Capital, LP61,606$185K<0.01%013F-HRTimeline
MYDA Advisors LLC50,000$150K0.04%new13F-HRTimeline
Qube Research & Technologies Ltd49,932$150K<0.01%+38,64613F-HRTimeline
UNIVERSITY OF CHICAGO48,731$147K0.03%013F-HRTimeline
CITADEL ADVISORS LLCin group CITADEL ADVISORS LLC47,317$142K<0.01%-13,93213F-HRTimelineGroup
Quadrature Capital Ltdin group Quadrature Capital Ltd47,067$142K<0.01%new13F-HRTimelineGroup
GOLDMAN SACHS GROUP INCin group GOLDMAN SACHS GROUP INC45,900$138K<0.01%-1,02013F-HRTimelineGroup
Verdad Advisers, LP44,899$135K0.13%new13F-HRTimeline
LPL Financial LLC43,554$131K<0.01%+10,00013F-HRTimeline
COMMONWEALTH EQUITY SERVICES, LLC42,455$128K<0.01%+7,70013F-HRTimeline
J. Derek Lewis & Associates Inc.42,000$126K0.02%-1,00013F-HRTimeline
CITIGROUP INCin group CITIGROUP INC38,205$115K<0.01%+36,46513F-HRTimelineGroup
SIMPLEX TRADING, LLC37,902$114K<0.01%+37,64913F-HRTimeline
Point72 Asset Management, L.P.in group Point72 Asset Management, L.P.37,092$112K<0.01%+5,08613F-HRTimelineGroup
Walleye Capital LLCin group Walleye Capital LLC36,778$111K<0.01%new13F-HRTimelineGroup
DIMENSIONAL FUND ADVISORS LPin group DIMENSIONAL FUND ADVISORS LP36,175$109K<0.01%+10,26313F-HRTimelineGroup
MORGAN STANLEYin group MORGAN STANLEY33,448$101K<0.01%-36,24013F-HRTimelineGroup
MACKENZIE FINANCIAL CORP26,343$79.3K<0.01%new13F-HRTimeline
Cetera Investment Advisers25,000$75.2K<0.01%-2,26013F-HRTimeline
Graham Capital Management, L.P.22,708$68.4K<0.01%-4013F-HRTimeline
OSAIC HOLDINGS, INC.in group OSAIC HOLDINGS, INC.17,721$53.3K<0.01%+4,00013F-HRTimelineGroup
GROUP ONE TRADING LLC16,480$49.6K<0.01%new13F-HRTimeline
FMR LLCin group FMR LLC12,383$37.3K<0.01%+47113F-HRTimelineGroup
PACES FERRY WEALTH ADVISORS, LLC11,440$34.4K0.01%013F-HRTimeline
NewEdge Advisors, LLC10,250$30.9K<0.01%013F-HRTimeline
China Universal Asset Management Co., L…10,083$30.4K<0.01%-96613F-HRTimeline
Tower Research Capital LLC (TRC)in group Tower Research Capital LLC (T…9,398$28.3K<0.01%-93413F-HRTimelineGroup
PNC Financial Services Group, Inc.in group PNC Financial Services Group,…6,500$19.6K<0.01%013F-HRTimelineGroup
Winthrop Capital Management, LLC6,000$18K<0.01%013F-HRTimeline
JPMORGAN CHASE & COin group JPMORGAN CHASE & CO5,545$15.9K<0.01%+37213F-HRTimelineGroup
HAGER INVESTMENT MANAGEMENT SERVICES, L…5,000$15.1K0.01%013F-HRTimeline
BARCLAYS PLCin group BARCLAYS PLC4,669$14.1K<0.01%-45,15613F-HRTimelineGroup
Federation des caisses Desjardins du Qu…4,500$13.5K<0.01%new13F-HRTimeline
FEDERATED HERMES, INC.in group FEDERATED HERMES, INC.2,962$8.92K<0.01%-21913F-HRTimelineGroup
Mirae Asset Global Investments Co., Ltd.in group Mirae Asset Global Investment…2,833$8.53K<0.01%-41513F-HRTimelineGroup
BNP PARIBAS FINANCIAL MARKETSin group BNP PARIBAS FINANCIAL MARKETS2,689$8.09K<0.01%+1,03513F-HRTimelineGroup
FIRST UNITED BANK & TRUST2,500$7.38K<0.01%new13F-HRTimeline
GF FUND MANAGEMENT CO. LTD.1,226$3.69K<0.01%-9013F-HRTimeline
NISA INVESTMENT ADVISORS, LLC961$2.89K<0.01%013F-HRTimeline
Physician Wealth Advisors, Inc.943$2.84K<0.01%013F-HRTimeline
SBI Securities Co., Ltd.509$1.53K<0.01%+50813F-HRTimeline
JONES FINANCIAL COMPANIES LLLPin group JONES FINANCIAL COMPANIES LLLP500$1.39K<0.01%013F-HRTimelineGroup
WELLS FARGO & COMPANY/MNin group WELLS FARGO & COMPANY/MN285$858<0.01%013F-HRTimelineGroup
Cornerstone Financial Management LLC172$518<0.01%013F-HR/ATimeline
Caitong International Asset Management …35$105<0.01%+3113F-HRTimeline
Arax Advisory Partners14$42<0.01%+1313F-HRTimeline

Events

  • Coastlands Capital LP and 4 other reporting persons reported 6,448,907 PYXS shares, 5.42% of the class, as of 2026-10-01, in a 13G filed 2026-10-05. 0001104659-26-113597

    Accepted , ingested

  • GordonMD Global Investments LP and 3 other reporting persons reported 27,988,714 PYXS shares, 17.5% of the class, as of 2026-10-01, in a 13G/A filed 2026-10-02. 0000919574-26-006608

    Accepted , ingested