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Disclosery

ORBIMED ADVISORS LLC: APLS position timeline

Available 13F reports, 13D and 13G stakes and each Form 3, 4 and 5 line of ORBIMED ADVISORS LLC on APLS, newest first. How the timeline and the estimate are built.

ORBIMED ADVISORS LLC held 0 APLS shares at 2026-03-31 per its 13F-HR filed 2026-05-15.

the latest 13F is the newest step

  1. period ended2026-03-31
    13F 0 shares
    Change vs previous 13F -2,429,868 shares

    13F-HR 0001172661-26-002369 filed by ORBIMED ADVISORS LLC
    Filed (acceptance time not in the bulk data set), ingested

    Acceptance time not in the bulk data set (spec §4.2).

    Exited: the 13F for this period no longer lists the position.

  2. period ended2025-12-31
    13F 2,429,868 shares
    Change vs previous 13F +106,500 shares

    1.25% of the 13F portfolio, value $61,038,284.

    13F-HR 0001172661-26-001119 filed by ORBIMED ADVISORS LLC
    Filed (acceptance time not in the bulk data set), ingested

    Acceptance time not in the bulk data set (spec §4.2).

  3. period ended2025-09-30
    13F 2,323,368 shares
    Change vs previous 13F +841,068 shares

    1.26% of the 13F portfolio, value $52,577,818.

    13F-HR 0001172661-25-005047 filed by ORBIMED ADVISORS LLC
    Filed (acceptance time not in the bulk data set), ingested

    Acceptance time not in the bulk data set (spec §4.2).

  4. period ended2025-06-30
    13F 1,482,300 shares
    Change vs previous 13F +50,000 shares

    0.65% of the 13F portfolio, value $25,658,613.

    13F-HR 0001172661-25-003514 filed by ORBIMED ADVISORS LLC
    Filed (acceptance time not in the bulk data set), ingested

    Acceptance time not in the bulk data set (spec §4.2).

  5. period ended2025-03-31
    13F 1,432,300 shares
    Change vs previous 13F +1,432,300 shares

    0.75% of the 13F portfolio, value $31,324,401.

    13F-HR 0001172661-25-002355 filed by ORBIMED ADVISORS LLC
    Filed (acceptance time not in the bulk data set), ingested

    Acceptance time not in the bulk data set (spec §4.2).

  6. period ended2024-12-31
    13F 0 shares
    Change vs previous 13F -1,270,400 shares

    13F-HR 0001172661-25-001136 filed by ORBIMED ADVISORS LLC
    Filed (acceptance time not in the bulk data set), ingested

    Acceptance time not in the bulk data set (spec §4.2).

    Exited: the 13F for this period no longer lists the position.

  7. period ended2024-09-30
    13F 1,270,400 shares
    Change vs previous 13F not available

    0.67% of the 13F portfolio, value $36,638,336.

    13F-HR 0001172661-24-005167 filed by ORBIMED ADVISORS LLC
    Filed (acceptance time not in the bulk data set), ingested

    Acceptance time not in the bulk data set (spec §4.2).